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Globally, infant mortality is used as an important indicator for healthcare status hence an important tool for evaluation and planning of public health strategies. Despite of numerous interventions by governments aimed at reducing infant mortality, high rates are still reported in Kenya. A lot of resources are channeled towards its control leading to low productivity hence impacting the household economic welfare and national GD. The specific objective was to establish risk factors and the spatial variation of infant mortality in Kenya by analyzing the 2014 Kenya Demographic Health Survey data. A fully Bayesian paradigm and logistic regression model were used to determine infant mortality risk factors and spatial variation in Kenya. Demographic, socioeconomic and environmental factors were found to have significant effect on infant mortality. Counties from the northern parts of Kenya, Rift Valley, Central, Eastern, Nyanza, Coastal and Western parts of Kenya showed a high level of infant deaths. Infant mortality is high in arid and semi-arid areas and coastal areas due to high prevalence of infectious diseases and inadequate water supply, health facilities and low education levels. Infant mortality varies significantly across regions in Kenya due to cultural activities, and weather patterns hence exists spatial autocorrelation among neighboring regions.