7 results on '"Eric O. Stinson"'
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2. VectorBase: a home for invertebrate vectors of human pathogens.
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Daniel Lawson, Peter Arensburger, Peter Atkinson, Nora J. Besansky, Robert V. Bruggner, Ryan Butler, Kathryn S. Campbell, George K. Christophides, Scott Christley, Emmanuel Dialynas, David B. Emmert, Martin Hammond, Catherine A. Hill, Ryan C. Kennedy, Neil F. Lobo, Robert M. MacCallum, Gregory R. Madey, Karine Megy, Seth Redmond, Susan Russo, David W. Severson, Eric O. Stinson, Pantelis Topalis, Evgeni M. Zdobnov, Ewan Birney, William M. Gelbart, Fotis C. Kafatos, Christos Louis, and Frank H. Collins
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- 2007
- Full Text
- View/download PDF
3. Genome sequence of Aedes aegypti, a major arbovirus vector
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Sergio Verjovski-Almeida, James E. Galagan, Ryan C. Kennedy, Zhiyong Xi, Jason R. Miller, Eric Eisenstadt, Kyanne R. Reidenbach, Robert V. Bruggner, Yu-Hui Rogers, Hadi Quesneville, Doreen Werner, Owen White, Alexander S. Raikhel, Mario Stanke, J. Spencer Johnston, Diane D. Lovin, Evgenia V. Kriventseva, Ian T. Paulsen, Kathryn S. Campbell, Norman H. Lee, Ewan Birney, Karyn Megy, Hean Koo, David Kulp, Shelby L. Bidwell, Jingsong Zhu, Philip Montgomery, Paolo Amedeo, Yongmei Zhao, Chinnappa D. Kodira, Javier Costas, Michael C. Schatz, Steven P. Sinkins, Claire M. Fraser-Liggett, Martin Shumway, Kurt LaButti, Akio Mori, Brendan J. Loftus, Manfred Grabherr, Eric O. Stinson, Frank H. Collins, Zhijian Jake Tu, Monique R. Coy, Matt Crawford, Janice P. Vanzee, William M. Gelbart, Joshua Orvis, Peter Arensburger, Chunhong Mao, Evgeny M. Zdobnov, Saul A. Kravitz, Suely Lopes Gomes, David DeCaprio, David G. Hogenkamp, Daniel Lawson, Dennis L. Knudson, David W. Severson, George Dimopoulos, Marcelo B. Soares, Sinéad B. O'Leary, Peter W. Atkinson, David M. Jaffe, Becky deBruyn, Martin Hammond, Ana L. T. O. Nascimento, Jim Biedler, Stefan Wyder, Jose M. C. Tubio, Bruce W. Birren, Catherine A. Hill, Chad Nusbaum, Eduardo Lee, Song Li, Susan E. Brown, Jennifer R. Wortman, James R. Hogan, Hamza El-Dorry, Qi Zhao, Linda Hannick, Carlos Frederico Martins Menck, Vishvanath Nene, Jonathan Crabtree, Steven L. Salzberg, Michael H. Holmes, Maria de Fatima Bonaldo, Quinghu Ren, Mihaela Pertea, Charles Roth, Evan Mauceli, Karin Eiglmeier, Horacio Naveira, Brian J. Haas, Qiandong Zeng, Neil F. Lobo, Jennifer R. Schneider, The Institute for Genomic Research, The Institute for Genomic Research, Rockville, European Bioinformatics Institute [Hinxton] ( EMBL-EBI ), European Molecular Biology Laboratory [Hinxton], Broad Institute of MIT and Harvard ( BROAD INSTITUTE ), Broad Institute of MIT and Harvard, Virginia Polytechnic Institute and State University [Blacksburg], University College Dublin [Dublin] ( UCD ), Bloomberg School of Public Health, Johns Hopkins University ( JHU ) -Bloomberg School of Public Health, University of Geneva Medical School, Swiss Institute of Bioinformatics-University of Geneva Medical School, University of Notre Dame ( UND ), Harvard University [Cambridge], College of Agricultural Sciences Colorado State University, Colorado State University [Fort Collins] ( CSU ) -College of Agricultural Sciences, Northwestern University [Evanston], University of California [Riverside] ( UCR ), Department of Atmospheric, Oceanic and Planetary Physics [Oxford] ( AOPP ), University of Oxford [Oxford], Purdue University [West Lafayette], Centro Nacional de Genotipado Fundación Pública Galega de Medicina Xenómica Hospital Clínico Universitario de Santiago, Centro Nacional de Genotipado-Fundación Pública Galega de Medicina Xenómica-Hospital Clínico Universitario de Santiago, Institut Pasteur [Paris], Universidade de Sao Paulo Instituto de Quimica, Universidade de São Paulo ( USP ) -Instituto de Quimica, Texas A&M University [College Station], Joint Technology Center, University of Massachusetts [Amherst] ( UMass Amherst ), Universidade de Sao Paulo, Institute of Biomedical Sciences, Universidade de São Paulo ( USP ) -Institute of Biomedical Sciences, Instituto Butantan [São Paulo], Universidade da Coruña, University of Maryland [College Park], Institut Jacques Monod ( IJM ), Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), University of California [Santa Cruz] ( UCSC ), Complexo Hospitalario Universitario de Santiago, Universität Göttingen, Georg-August-Universität Göttingen, George Washington University Medical Center, George Washington University ( GW ), The Institute for Genomic Research (TIGR), European Bioinformatics Institute [Hinxton] (EMBL-EBI), EMBL Heidelberg, Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], University College Dublin [Dublin] (UCD), Johns Hopkins Bloomberg School of Public Health [Baltimore], Johns Hopkins University (JHU), Swiss Institute of Bioinformatics [Lausanne] (SIB), Université de Lausanne (UNIL)-Université de Lausanne (UNIL)-University of Geneva Medical School, University of Notre Dame [Indiana] (UND), Colorado State University [Fort Collins] (CSU)-College of Agricultural Sciences, University of California [Riverside] (UCR), University of California, Department of Atmospheric, Oceanic and Planetary Physics [Oxford] (AOPP), Universidade de São Paulo (USP)-Instituto de Quimica, University of Massachusetts [Amherst] (UMass Amherst), University of Massachusetts System (UMASS), Universidade de São Paulo (USP)-Institute of Biomedical Sciences (ICB/USP), Universidade de São Paulo (USP), University of Maryland System, Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), University of California [Santa Cruz] (UCSC), Georg-August-University [Göttingen], The George Washington University (GW), George Washington University (GW), Université de Lausanne = University of Lausanne (UNIL)-Université de Lausanne = University of Lausanne (UNIL)-University of Geneva Medical School, Harvard University, University of California [Riverside] (UC Riverside), University of California (UC), University of Oxford, Institut Pasteur [Paris] (IP), Universidade de São Paulo = University of São Paulo (USP)-Instituto de Quimica, Universidade de São Paulo = University of São Paulo (USP)-Institute of Biomedical Sciences (ICB/USP), Universidade de São Paulo = University of São Paulo (USP), University of California [Santa Cruz] (UC Santa Cruz), Georg-August-University = Georg-August-Universität Göttingen, Zdobnov, Evgeny, and Wyder, Stefan
- Subjects
0106 biological sciences ,Male ,Transcription, Genetic ,Genome, Insect ,transposons ,receptors ,Genes, Insect ,Aedes/ genetics/metabolism ,MESH: Genes, Insect ,Yellow Fever/prevention & control/transmission ,MESH: Base Sequence ,01 natural sciences ,Dengue/prevention & control/transmission ,MESH: Protein Structure, Tertiary ,MESH: Arboviruses ,MESH : Insect Vectors ,MESH: Insect Proteins ,MESH : Anopheles gambiae ,MESH: Animals ,MESH : Arboviruses ,insects ,MESH: Yellow Fever ,superfamily ,ddc:616 ,0303 health sciences ,Anopheles ,MESH : Genes, Insect ,3. Good health ,yellow-fever mosquito ,anopheles-gambiae ,drosophila-melanogaster ,expression ,evolution ,organization ,Drosophila melanogaster ,MESH: DNA Transposable Elements ,[ SDV.BBM.GTP ] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN] ,Multigene Family ,Public Health ,MESH : Protein Structure, Tertiary ,MESH: Sex Characteristics ,Molecular Sequence Data ,MESH : Multigene Family ,MESH: Sex Determination (Genetics) ,MESH : Sex Determination (Genetics) ,Arbovirus ,Article ,03 medical and health sciences ,Species Specificity ,[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN] ,MESH: Anopheles gambiae ,Yellow Fever ,MESH: Species Specificity ,Humans ,MESH: Humans ,MESH: Molecular Sequence Data ,fungi ,MESH : Humans ,MESH : Sex Characteristics ,Membrane Transport Proteins ,Sex Determination Processes ,medicine.disease ,Insect Vectors ,Protein Structure, Tertiary ,Sex Determination (Genetics) ,MESH: Multigene Family ,MESH: Female ,MESH : Sequence Analysis, DNA ,MESH: Sequence Analysis, DNA ,Drosophila melanogaster/genetics ,MESH : Molecular Sequence Data ,Odorant binding ,Insect Proteins/genetics ,Anopheles gambiae ,MESH: Dengue ,Genome ,MESH: Membrane Transport Proteins ,Dengue ,MESH : Membrane Transport Proteins ,Aedes ,Insect Vectors/ genetics/metabolism ,MESH : Drosophila melanogaster ,MESH : Female ,Membrane Transport Proteins/genetics ,Genetics ,MESH : Insect Proteins ,Sex Characteristics ,Multidisciplinary ,MESH: Synteny ,MESH: Aedes ,MESH : Genome, Insect ,MESH : DNA Transposable Elements ,Insect Proteins ,Female ,Orthologous Gene ,MESH : Male ,MESH : Dengue ,Aedes aegypti ,MESH: Insect Vectors ,Biology ,010603 evolutionary biology ,Synteny ,MESH: Drosophila melanogaster ,Protein Structure, Tertiary/genetics ,MESH : Yellow Fever ,parasitic diseases ,medicine ,MESH : Species Specificity ,Animals ,030304 developmental biology ,MESH : Aedes ,Base Sequence ,MESH: Genome, Insect ,MESH: Transcription, Genetic ,MESH : Synteny ,MESH : Transcription, Genetic ,Sequence Analysis, DNA ,biology.organism_classification ,MESH: Male ,DNA Transposable Elements ,MESH : Base Sequence ,MESH : Animals ,Arboviruses ,Anopheles gambiae/genetics/metabolism - Abstract
We present a draft sequence of the genome of Aedes aegypti , the primary vector for yellow fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae . Nearly 50% of the Ae. aegypti genome consists of transposable elements. These contribute to a factor of ∼4 to 6 increase in average gene length and in sizes of intergenic regions relative to An. gambiae and Drosophila melanogaster . Nonetheless, chromosomal synteny is generally maintained among all three insects, although conservation of orthologous gene order is higher (by a factor of ∼2) between the mosquito species than between either of them and the fruit fly. An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species.
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- 2016
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4. VectorBase: a data resource for invertebrate vector genomics
- Author
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William M. Gelbart, Fotis C. Kafatos, Robert V. Bruggner, Peter W. Atkinson, Ryan Butler, Nora J. Besansky, Karyn Megy, Scott Christley, Frank H. Collins, Peter Arensburger, Jason M. Meyer, Daniel Lawson, George K. Christophides, Robert M. MacCallum, Nathan Konopinski, Pantelis Topalis, Martin Hammond, Catherine A. Hill, Gregory R. Madey, Emmanuel Dialynas, Kathryn S. Campbell, Eric O. Stinson, David W. Severson, Christos Louis, Neil F. Lobo, Seth Redmond, and Ewan Birney
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Anopheles gambiae ,030231 tropical medicine ,Genome, Insect ,Genomics ,Computational biology ,Pediculus humanus ,03 medical and health sciences ,0302 clinical medicine ,Aedes ,parasitic diseases ,Anopheles ,Databases, Genetic ,Genetics ,Animals ,030304 developmental biology ,0303 health sciences ,biology ,Ixodes ,Ecology ,Gene Expression Profiling ,Arthropod Vectors ,Pediculus ,Articles ,biology.organism_classification ,3. Good health ,Culex ,Culicidae ,Vocabulary, Controlled ,Ixodes scapularis ,Vector (epidemiology) ,Arthropod Vector - Abstract
VectorBase (http://www.vectorbase.org) is an NIAID-funded Bioinformatic Resource Center focused on invertebrate vectors of human pathogens. VectorBase annotates and curates vector genomes providing a web accessible integrated resource for the research community. Currently, VectorBase contains genome information for three mosquito species: Aedes aegypti, Anopheles gambiae and Culex quinquefasciatus, a body louse Pediculus humanus and a tick species Ixodes scapularis. Since our last report VectorBase has initiated a community annotation system, a microarray and gene expression repository and controlled vocabularies for anatomy and insecticide resistance. We have continued to develop both the software infrastructure and tools for interrogating the stored data.
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- 2008
5. Anatomical ontologies of mosquitoes and ticks, and their web browsers in VectorBase
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Frank H. Collins, C. Tzavlaki, Daniel E. Sonenshine, Robert V. Bruggner, Pantelis Topalis, Eric O. Stinson, Emmanuel Dialynas, K. Vestaki, Ryan Butler, and Christos Louis
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Biological data ,Relational database ,Genome project ,Biology ,Ontology (information science) ,Bioinformatics ,World Wide Web ,Annotation ,Insect Science ,Controlled vocabulary ,Genetics ,Anatomical terms of location ,Molecular Biology ,Arthropod Vector - Abstract
VectorBase, an integrated, relational database that manages genomic and other genetic/biological data pertaining to arthropod vectors of disease, has recently embarked on the construction of ontologies and controlled vocabularies (CVs). It aims, thus, at providing all necessary tools for the complete annotation of vector genomes and, in particular, the annotation of functional genomic data. This task was initiated with the development of anatomical ontologies of mosquitoes and ticks, both of which were made compliant to CARO, the common anatomy reference ontology. The ontologies are complemented by the development of novel web-based browsers that can show figures for anatomical terms, something that is especially helpful for fully illustrating the controlled vocabularies of anatomy.
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- 2008
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- View/download PDF
6. Implementation of VectorBase Components: EnsEMBL Genome Browser, Search, and Database Tools
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Eric O Stinson
- Published
- 2007
- Full Text
- View/download PDF
7. VectorBase: a home for invertebrate vectors of human pathogens
- Author
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Seth Redmond, Robert V. Bruggner, Evgeni M. Zdobnov, Karyn Megy, Fotis C. Kafatos, Emmanuel Dialynas, David W. Severson, Kathryn S. Campbell, Susan M. Russo, Ryan C. Kennedy, David B. Emmert, Ewan Birney, Scott Christley, Pantelis Topalis, Nora J. Besansky, George K. Christophides, Frank H. Collins, Neil F. Lobo, Peter Arensburger, Ryan Butler, Eric O. Stinson, Peter W. Atkinson, Catherine A. Hill, Gregory R. Madey, Martin Hammond, Christos Louis, William M. Gelbart, Daniel Lawson, and Robert M. MacCallum
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Anopheles gambiae ,030231 tropical medicine ,Genome, Insect ,Aedes aegypti ,Dengue fever ,03 medical and health sciences ,User-Computer Interface ,0302 clinical medicine ,Aedes ,Anopheles ,parasitic diseases ,Databases, Genetic ,Genetics ,medicine ,Animals ,Humans ,Conserved Sequence ,030304 developmental biology ,ddc:616 ,0303 health sciences ,Internet ,biology ,Base Sequence ,Insect Vectors/ genetics ,Yellow fever ,Articles ,Aedes/ genetics ,Genomics ,medicine.disease ,biology.organism_classification ,Virology ,Insect Vectors ,3. Good health ,Vector (epidemiology) ,Anopheles gambiae/ genetics ,Malaria - Abstract
VectorBase (http://www.vectorbase.org/) is a web-accessible data repository for information about invertebrate vectors of human pathogens. VectorBase annotates and maintains vector genomes providing an integrated resource for the research community. Currently, VectorBase contains genome information for two organisms: Anopheles gambiae, a vector for the Plasmodium protozoan agent causing malaria, and Aedes aegypti, a vector for the flaviviral agents causing Yellow fever and Dengue fever.
- Published
- 2007
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