Search

Your search keyword '"Eom, Ki-Seong"' showing total 1,099 results
Start Over Author "Eom, Ki-Seong"
1,099 results on '"Eom, Ki-Seong"'

3. Reduced toxicity (FluBu3) versus myeloablative (BuCy) conditioning in acute myeloid leukemia patients who received first allogeneic hematopoietic stem cell transplantation in measurable residual disease-negative CR1

Author

Park, Silvia, Bang, Su-Yeon, Kwag, Daehun, Lee, Jong Hyuk, Kim, Tong Yoon, Lee, Joonyeop, Min, Gi June, Park, Sung Soo, Yahng, Seung-Ah, Jeon, Young-Woo, Shin, Seung-Hwan, Yoon, Jae-Ho, Lee, Sung-Eun, Cho, Byung Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Lee, Seok, Min, Chang-Ki, Cho, Seok-Goo, Lee, Jong Wook, and Kim, Hee-Je

Published
2024
Full Text
View/download PDF

8. Hematopoietic stem cell transplantation to improve prognosis in aggressive monomorphic epitheliotropic intestinal T-cell lymphoma.

Author

Min, Gi-June, Oh, Ye Eun, Jeon, Youngwoo, Kim, Tong Yoon, Kim, Byung-Su, Kwag, Daehun, Park, Sung-Soo, Park, Silvia, Yoon, Jae-Ho, Lee, Sung-Eun, Cho, Byung-Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Lee, Seok, Kim, Hee-Je, Min, Chang-Ki, Lee, Jong Wook, and Cho, Seok-Goo

Subjects
HEMATOPOIETIC stem cell transplantation, BOWEL obstructions, T-cell lymphoma, KILLER cells, INTESTINAL perforation, STEM cell transplantation
Abstract

Introduction: Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare, aggressive subtype of primary gastrointestinal T-cell lymphoma. Owing to the absence of symptoms characteristic of MEITL, diagnosis can be challenging, and the low response rate to conventional chemotherapy leads to an abysmal prognosis. This study aimed to define the clinicopathologic characteristics of MEITL in Korea, evaluate the clinical outcomes of intensive chemotherapy with and without hematopoietic stem cell transplantation (HSCT), and explore prognostic factors. Methods: This single-center retrospective study examined the clinical data of 35 patients diagnosed with MEITL at Seoul St. Mary's Hospital from May 2012 to May 2023. Results: We included 22 men and 13 women (median age: 59 years; range: 37–79 years). Many patients exhibited acute abdominal pain (n=23, 65.7%) related to bowel perforation (n=21, 60.0%). Most patients (30/35, 85.7%) underwent surgical intervention to diagnose MEITL, whereas only five were diagnosed via endoscopic evaluation. Of the 32 patients receiving first-line therapy, 4 died before assessment, 10 achieved a complete response (CR), 6 had a relapse, and 18 exhibited progressive disease (PD). Seven of 10 patients received upfront HSCT, either autologous (auto-HSCT, n=4) or allogeneic (allo-HSCT, n=3). All four patients on auto-HSCT died after relapse. All three patients who received allo-HSCT maintained a CR by the final follow-up. Three of 6 patients who relapsed and 13 of 18 exhibiting PD received salvage therapy; one patient on salvage auto-HSCT with cytokine-induced killer cell infusion has survived progression free. Salvage allo-HSCT was performed on 6 of 16 patients; among them, 2 achieved a CR, 2 died after relapse, and 2 died owing to septic shock while maintaining a CR. The remaining patients, who received salvage therapy without HSCT, mostly died owing to PD. The median overall survival was 12.1 months, and the median follow-up was 33.2 months. The 1- and 5-year overall survival was 50.9% and 13.3%, respectively. Discussion: MEITL is an aggressive disease resistant to conventional therapy. Therefore, intensive chemotherapy followed by upfront allo-HSCT should be considered upon diagnosis. These findings underscore the need for novel therapeutic strategies and further investigation into optimizing treatment protocols for MEITL. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

11. Prediction and recommendation by machine learning through repetitive internal validation for hepatic veno-occlusive disease/sinusoidal obstruction syndrome and early death after allogeneic hematopoietic cell transplantation

Author

Lee, Seungjoon, Lee, Eunsaem, Park, Sung-Soo, Park, Min Sue, Jung, Jaewoo, Min, Gi June, Park, Silvia, Lee, Sung-Eun, Cho, Byung-Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Lee, Seok, Kim, Hee-Je, Min, Chang-Ki, Cho, Seok-Goo, Lee, Jong Wook, Hwang, Hyung Ju, and Yoon, Jae-Ho

Published
2022
Full Text
View/download PDF

17. The Impact of Histologic Portal T-Cell Density on the Clinical Outcomes in Hepatic Graft-versus-Host Disease and Autoimmune Liver Diseases.

Author

Lee, Soon Kyu, Park, Sung-Soo, Park, Silvia, Lee, Sung-Eun, Cho, Byung-Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Kim, Hee-Je, Min, Chang-Ki, Cho, Seok-Goo, Lee, Jong Wook, Lee, Seok, Kim, Younghoon, Han, Ji Won, Yang, Hyun, Bae, Si Hyun, Jang, Jeong Won, Choi, Jong Young, Yoon, Seung Kew, and Lee, Dong Yeup

Subjects
AUTOIMMUNE hepatitis, GRAFT versus host disease, HEMATOPOIETIC stem cells, STEM cell transplantation, AUTOIMMUNE diseases, HEPATIC veno-occlusive disease
Abstract

Hepatic graft-versus-host disease (GVHD) significantly impacts morbidity and mortality among allogeneic hematopoietic stem cell transplant recipients. However, the relationship between clinical and immunopathological phenotypes and their influence on clinical outcomes in hepatic GVHD is not well understood. In this study, we aimed to study the implications of portal T-cell infiltration on the clinical outcomes in hepatic GHVD and its similarities to autoimmune liver disease. We analyzed 78 patients with biopsy-confirmed hepatic GVHD (n = 38) or autoimmune liver disease (n = 40) between 2016 and 2021. The cholestatic variant was defined by an R-value < 2.0, based on the ratio of alanine aminotransferase to alkaline phosphatase. The primary outcome was the biochemical response at 4 (early) and 8–12 (late) weeks after corticosteroid treatment. In hepatic GVHD patients, the hepatitic variant (n = 19) showed greater CD3+ T-cell infiltration than the cholestatic variant (n = 19; p < 0.001). No significant differences were observed in the infiltration of CD20+, CD38+, or CD68+ cells. The hepatitic variant had significantly better early and late responses and higher liver-related event-free survival than the cholestatic variants (p < 0.05). Concerning autoimmune liver diseases, the autoimmune hepatitis (AIH) group had significantly more portal T-cell infiltration and better treatment responses than the primary biliary cholangitis (PBC) group. In conclusion, higher portal T-cell infiltration may be associated with better clinical outcomes in patients with hepatic GVHD. Additionally, this study highlights similarities in portal T-cell infiltration and treatment response patterns between AIH and the hepatitic variant, as well as PBC and the cholestatic variant. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

18. Comparison of Myeloablative (CyTBI, BuCy) versus Reduced-Intensity (FluBu2TBI400) Peripheral Blood Stem Cell Transplantation in Acute Myeloid Leukemia Patients with Pretransplant Low WT1 Expression

Author

Park, Silvia, Min, Gi June, Park, Sung Soo, Yahng, Seung-Ah, Jeon, Young-Woo, Shin, Seung-Hwan, Yoon, Jae-Ho, Lee, Sung-Eun, Cho, Byung Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Lee, Seok, Min, Chang-Ki, Cho, Seok-Goo, Kim, Dong-Wook, Lee, Jong Wook, and Kim, Hee-Je

Published
2020
Full Text
View/download PDF

25. WT1 Measurable Residual Disease Assay in Patients With Acute Myeloid Leukemia Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation: Optimal Time Points, Thresholds, and Candidates

Author

Cho, Byung-Sik, Min, Gi-June, Park, Sung-Su, Shin, Seung-Hwan, Yahng, Seung-Ah, Jeon, Young-Woo, Yoon, Jae-Ho, Lee, Sung-Eun, Eom, Ki-Seong, Kim, Yoo-Jin, Lee, Seok, Min, Chang-Ki, Cho, Seok-Goo, Kim, Dong-Wook, Lee, Jong-Wook, Kim, Myungsin, Kim, Younggu, and Kim, Hee-Je

Published
2019
Full Text
View/download PDF

27. Clinical Outcomes of Fludarabine and Melphalan With an 800 cGy Total Body Irradiation Conditioning Regimen in Patients With Refractory or Relapsed Aggressive Non-Hodgkin Lymphoma Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Author

Jeon, Young-Woo, Yoon, Seugyun, Min, Gi June, Park, Sung-Soo, Park, Silvia, Yoon, Jae-Ho, Lee, Sung-Eun, Cho, Byung-Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Kim, Hee-Je, Lee, Seok, Min, Chang-Ki, Lee, Jong Wook, and Cho, Seok-Goo

Published
2019
Full Text
View/download PDF

28. Prognostic Role Of Physical Function in Older Adults with Acute Myeloid Leukemia Treated by Lower-Intensity Therapy: A Prospective Cohort Study

Author

Kwag, Daehun, primary, Cho, Byung-Sik, additional, Min, Gi-June, additional, Park, Sung-Soo, additional, Park, Silvia, additional, Yoon, Jae-Ho, additional, Lee, Sung-Eun, additional, Eom, Ki-Seong, additional, Kim, Yoo-Jin, additional, Lee, Seok, additional, Min, Chang-Ki, additional, Cho, Seok-Goo, additional, Lee, Jong Wook, additional, and Kim, Hee-Je, additional

Published
2024
Full Text
View/download PDF

30. Reduced toxicity (FluBu3) versus myeloablative (BuCy) conditioning in acute myeloid leukemia patients who received first allogeneic hematopoietic stem cell transplantation in measurable residual disease-negative CR1

Author

Kim, Hee-Je, primary, Park, Silvia, additional, Bang, Su-Yeon, additional, Kwag, Daehun, additional, Min, Gi June, additional, Park, Sung-Soo, additional, Yoon, Jae-Ho, additional, Lee, Sung-Eun, additional, Cho, Byung-Sik, additional, Eom, Ki-Seong, additional, Kim, Yoo-Jin, additional, Lee, Seok, additional, Min, Chang-Ki, additional, Cho, Seok-Goo, additional, Lee, Jong Wook, additional, Lee, Jong Hyuk, additional, Yahng, Seung-Ah, additional, Kim, Tong Yoon, additional, Jeon, Youngwoo, additional, Lee, Joon yeop, additional, and Shin, Seung-Hwan, additional

Published
2023
Full Text
View/download PDF

31. Dynamic changes in physical function during intensive chemotherapy affect transplant outcomes in older adults with AML

Author

Min, Gi-June, primary, Cho, Byung-Sik, additional, Kwag, Daehun, additional, Park, Sung-Soo, additional, Park, Silvia, additional, Yoon, Jae-Ho, additional, Lee, Sung-Eun, additional, Eom, Ki-Seong, additional, Kim, Yoo-Jin, additional, Lee, Seok, additional, Min, Chang-Ki, additional, Cho, Seok-Goo, additional, Lee, Jong Wook, additional, and Kim, Hee-Je, additional

Published
2023
Full Text
View/download PDF

39. P1167: TREATMENT OF RELAPSED/REFRACTORY HGBCL WITH MYC REARRANGEMENT: A MULTICENTER, OPEN-LABEL, PHASE 2 STUDY OF PC-002(SEPB)，A FIRST-IN-CLASS INHIBITOR OF DEUBIQUITINASES TARGETING MYC DEGRADATION

Author

Yoon, Sung-Soo, primary, LI, Zhiming, additional, Zhou, Keshu, additional, Zhou, Xiaoxi, additional, Guo, Ye, additional, Zhang, Huilai, additional, Eom, Ki-Seong, additional, Jin Kim, Seok, additional, Yong Oh, Sung, additional, Lim, Sungnam, additional, Youssoufian, Hagop, additional, Jiang, Vernon C, additional, Huang, Zanchun, additional, Kilfoil, Georgina, additional, Wang, Xin, additional, Cao, Zhixiang, additional, LI, Xiang, additional, Wu, Alexander, additional, Chen, Yiyou, additional, and Song, Yuqin, additional

Published
2023
Full Text
View/download PDF

41. Beneficial Role of Low-Dose Antithymocyte Globulin in Unrelated Stem Cell Transplantation for Adult Patients with Acquired Severe Aplastic Anemia: Reduction of Graft-versus-Host Disease and Improvement of Graft-versus-Host Disease–Free, Failure-Free Survival Rate

Author

Park, Sung-Soo, Kwak, Dae Hun, Jeon, Young-Woo, Yoon, Jae-Ho, Lee, Sung-Eun, Cho, Byung-Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Kim, Hee-Je, Lee, Seok, Min, Chang-Ki, Cho, Seok-Goo, Kim, Dong-Wook, Min, Woo-Sung, and Lee, Jong Wook

Published
2017
Full Text
View/download PDF

44. Comparable Outcomes After Alternative and Matched Sibling Donor Hematopoietic Stem Cell Transplantation and the Role of Molecular Measurable Residual Disease for Acute Myeloid Leukemia in Elderly Patients

Author

Cho, Byung-Sik, Yahng, Seung-Ah, Min, Gi-June, Park, Silvia, Park, Sung-Soo, Shin, Seung-Hwan, Jeon, Young-Woo, Yoon, Jae-Ho, Lee, Sung-Eun, Eom, Ki-Seong, Kim, Yoo-Jin, Lee, Seok, Min, Chang-Ki, Cho, Seok-Goo, Kim, Dong-Wook, Lee, Jong Wook, Kim, Myungshin, Kim, Yonggoo, and Kim, Hee-Je

Published
2021
Full Text
View/download PDF

48. Negative Impact of Unidirectional Host-versus-Graft Killer Cell Immunoglobulin–like Receptor Ligand Mismatch on Transplantation Outcomes after Unmanipulated Haploidentical Peripheral Blood Stem Cell Transplantation for Acute Myeloid Leukemia

Author

Yahng, Seung-Ah, Jeon, Young-Woo, Yoon, Jae-Ho, Shin, Seung-Hwan, Lee, Sung-Eun, Cho, Byung-Sik, Eom, Ki-Seong, Kim, Yoo-Jin, Lee, Seok, Min, Chang-Ki, Cho, Seok-Goo, Kim, Dong-Wook, Lee, Jong-Wook, Min, Woo-Sung, and Kim, Hee-Je

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results