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2. Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study

Author

Ortega, Alicia, de la Fuente, Amanda, Almansa, Raquel, Postigo, Tamara, Jorge, Noelia, Tedim, Ana P, González-González, Laura, Sánchez Recio, Lara, Trapiello, Wysali, Berezo, José Ángel, Herrán-Monge, Rubén, Blanco, Jesús, Enríquez, Pedro, Martínez, Isidoro, Martín-Vicente, María, Muñoz-Gómez, María José, Más, Vicente, Vázquez, Mónica, Cano, Olga, Martínez de la Gándara, Amalia, Rodríguez, Covadonga, Andrade, Gloria, Renedo, Gloria, Bustamante-Munguira, Juan, Cicuendez Ávila, Ramón, Salgado-Villén, María, Berruguilla-Pérez, Enrique, Güell, Estel, Casadiego Monachello, Fernando Javier, Recuerda Núñez, María, Sánchez Calvo, Juan Manuel, Peñasco-Martín, Yhivian, García Unzueta, María Teresa, Ceccato, Adrián, Fernández-Barat, Laia, Bouza Vieiro, María Teresa, Moreno-Romero, Ana, Pérez Bastida, Leire, del Río-Carbajo, Lorena, Albalá Martínez, Noelia, Gómez, José Manuel, Blasco, María Luisa, Caballero, Jesús, Barberà, Carme, González, Jessica, Nieto, María Teresa, Nieto-del Olmo, Jorge, Prol-Silva, Estefanía, Canseco-Ribas, Joan, Eiros, Jose María, Bermejo-Martin, Jesús F, García-Mateo, Nadia, Motos, Anna, Resino, Salvador, Tamayo, Luis, Ryan Murua, Pablo, Bustamante-Munguira, Elena, Gallego Curto, Elena, Úbeda-Iglesias, Alejandro, de la Torre, María del Carmen, Estella, Ángel, Campos-Fernández, Sandra, Martínez Varela, Ignacio, Pérez-García, Felipe, Socias, Lorenzo, López Messa, Juan, Vidal-Cortés, Pablo, Sagredo Meneses, Víctor, González-Rivera, Milagros, Carbonell, Nieves, de Gonzalo-Calvo, David, Martín Delgado, María Cruz, Valdivia, Luis Jorge, Martín-López, Caridad, Jorge García, Ruth Noemí, Maseda, Emilio, Loza-Vázquez, Ana, Kelvin, David J, Barbé, Ferrán, and Torres, Antoni

Published
2023
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4. Geysers' Dust Dynamics Inside the Hill Sphere of Enceladus.

Author

Flandes, Alberto, Mirón‐Enríquez, Pedro Elías, and Ramírez‐Cabañas, Alma Karen

Subjects
*GEYSERS, *DUST, *ELECTRIC charge, *LORENTZ force, *SPHERES, *PARTICLE tracks (Nuclear physics)
Abstract

In this work, we study the trajectories of the dust particles ejected in the geysers of the moon Enceladus, inside its Hill sphere, where its gravitational influence dominates. Our goal is to determine the properties of the particles that escape from the moon or of those that eventually impact on its surface. The analysis considers the gravity of Enceladus, the Lorentz force due to Saturn's magnetic field and the gas drag from the geysers. The local magnetic field around Enceladus is derived from an interpolation of Cassini data from six flybys. In general, we obtain that grain sizes and launching speeds define whether grains escape, though the launching angle may also play an important role in some cases. Plain Language Summary: Dust grains expelled from the geysers of the small Saturnian moon Enceladus follow particular trajectories determined by the different forces like the gravity of the moon, the gas drag of the geysers and the magnetic field of Saturn. In this work we study the dynamics of these grains inside a region around the moon, called the Hill sphere, where its gravitational influence dominates, in order to determine the effects of the different forces on the grains, as well as the properties of grains, like their size, mass and electric charge. Key Points: We study the trajectories of dust grains from the geysers of Enceladus inside the Hill sphere of the moonWe implement an interpolated magnetic field background to study the trajectories of dust grainsWe study the dynamic properties of dust grains that are able to escape from Enceladus [ABSTRACT FROM AUTHOR]

Published
2024
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5. Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Micheloud, Dariela, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Ryan Murua, Pablo, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Fernández Natal, Isabel, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, de la Fuente, Amanda, del Campo, Félix, Fernández-Ratero, José Antonio, Trapiello, Wysali, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, García Olivares, Pablo, Cedeño, Jamil Antonio, Ruiz Albi, Tomás, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Abadia, Jesica, Gómez Barquero, Julia, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Fernández Caso, Belén, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Barbé, Ferrán, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Published
2020
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8. Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study

Author

Bermejo-Martin, Jesús F, primary, García-Mateo, Nadia, additional, Motos, Anna, additional, Resino, Salvador, additional, Tamayo, Luis, additional, Ryan Murua, Pablo, additional, Bustamante-Munguira, Elena, additional, Gallego Curto, Elena, additional, Úbeda-Iglesias, Alejandro, additional, de la Torre, María del Carmen, additional, Estella, Ángel, additional, Campos-Fernández, Sandra, additional, Martínez Varela, Ignacio, additional, Pérez-García, Felipe, additional, Socias, Lorenzo, additional, López Messa, Juan, additional, Vidal-Cortés, Pablo, additional, Sagredo Meneses, Víctor, additional, González-Rivera, Milagros, additional, Carbonell, Nieves, additional, de Gonzalo-Calvo, David, additional, Martín Delgado, María Cruz, additional, Valdivia, Luis Jorge, additional, Martín-López, Caridad, additional, Jorge García, Ruth Noemí, additional, Maseda, Emilio, additional, Loza-Vázquez, Ana, additional, Kelvin, David J, additional, Barbé, Ferrán, additional, Torres, Antoni, additional, Ortega, Alicia, additional, de la Fuente, Amanda, additional, Almansa, Raquel, additional, Postigo, Tamara, additional, Jorge, Noelia, additional, Tedim, Ana P, additional, González-González, Laura, additional, Sánchez Recio, Lara, additional, Trapiello, Wysali, additional, Berezo, José Ángel, additional, Herrán-Monge, Rubén, additional, Blanco, Jesús, additional, Enríquez, Pedro, additional, Martínez, Isidoro, additional, Martín-Vicente, María, additional, Muñoz-Gómez, María José, additional, Más, Vicente, additional, Vázquez, Mónica, additional, Cano, Olga, additional, Martínez de la Gándara, Amalia, additional, Rodríguez, Covadonga, additional, Andrade, Gloria, additional, Renedo, Gloria, additional, Bustamante-Munguira, Juan, additional, Cicuendez Ávila, Ramón, additional, Salgado-Villén, María, additional, Berruguilla-Pérez, Enrique, additional, Güell, Estel, additional, Casadiego Monachello, Fernando Javier, additional, Recuerda Núñez, María, additional, Sánchez Calvo, Juan Manuel, additional, Peñasco-Martín, Yhivian, additional, García Unzueta, María Teresa, additional, Ceccato, Adrián, additional, Fernández-Barat, Laia, additional, Bouza Vieiro, María Teresa, additional, Moreno-Romero, Ana, additional, Pérez Bastida, Leire, additional, del Río-Carbajo, Lorena, additional, Albalá Martínez, Noelia, additional, Gómez, José Manuel, additional, Blasco, María Luisa, additional, Caballero, Jesús, additional, Barberà, Carme, additional, González, Jessica, additional, Nieto, María Teresa, additional, Nieto-del Olmo, Jorge, additional, Prol-Silva, Estefanía, additional, Canseco-Ribas, Joan, additional, and Eiros, Jose María, additional

Published
2023
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9. Potential energy surfaces for singlet and triplet states of the LiH2+ system and quasi-classical trajectory cross sections for H + LiH+ and H+ + LiH.

Author

Hernández-Rodríguez, Javier, Sanz-Sanz, Cristina, Enríquez, Pedro Alberto, González, Miguel, and Paniagua, Miguel

Abstract

A new set of six accurate ab initio potential energy surfaces (PESs) is presented for the first three singlet and triplet states of LiH2+ (1,21A′, 11A′′, 1,23A′, and 13A′′ states, where four of them are investigated for the first time), which have allowed new detailed studies gaining a global view on this interesting system. These states are relevant for the study of the most important reactions of lithium chemistry in the early universe. More than 45 000 energy points were calculated using the multi-reference configuration interaction level of theory using explicitly correlated methods (ic-MRCI-F12), and the results obtained for each individual electronic state were fitted to an analytical function. Using quasiclassical trajectories and considering the initial diatomic fragment in the ground rovibrational state, we have determined the integral cross sections for the H + LiH+(X2Σ+, C2Π) and H+ + LiH(X1Σ+, B1Π) reactions. In these calculations all available reaction channels were considered: the chemically most important H or H+ transfer/abstraction as well as atom exchange and collision induced dissociation for up to 1.0 eV of collision energy. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients

Author

Martin‐Vicente, María, primary, Almansa, Raquel, additional, Martínez, Isidoro, additional, Tedim, Ana P., additional, Bustamante, Elena, additional, Tamayo, Luis, additional, Aldecoa, César, additional, Gómez, José Manuel, additional, Renedo, Gloria, additional, Berezo, Jose Ángel, additional, Cedeño, Jamil Antonio, additional, Mamolar, Nuria, additional, García Olivares, Pablo, additional, Herrán‐Monge, Rubén, additional, Cicuendez, Ramón, additional, Enríquez, Pedro, additional, Ortega, Alicia, additional, Jorge, Noelia, additional, Doncel, Cristina, additional, de la Fuente, Amanda, additional, Bustamante‐Munguira, Juan, additional, Muñoz‐Gómez, María José, additional, González‐Rivera, Milagros, additional, Puertas, Carolina, additional, Más, Vicente, additional, Vázquez, Mónica, additional, Pérez‐García, Felipe, additional, Rico‐Feijoo, Jesús, additional, Martín, Silvia, additional, Motos, Anna, additional, Fernandez‐Barat, Laia, additional, Eiros, Jose María, additional, Dominguez‐Gil, Marta, additional, Ferrer, Ricard, additional, Barbé, Ferrán, additional, Trapiello, Wysali, additional, Kelvin, David J., additional, Bermejo‐Martin, Jesús F., additional, Resino, Salvador, additional, and Torres, Antoni, additional

Published
2021
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14. The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant

Author

López, Mariana G., Chiner-Oms, Álvaro, García de Viedma, Darío, Ruiz-Rodriguez, Paula, Bracho, Maria Alma, Cancino-Muñoz, Irving, D’Auria, Giuseppe, de Marco, Griselda, García-González, Neris, Goig, Galo Adrian, Gómez-Navarro, Inmaculada, Jiménez-Serrano, Santiago, Martinez-Priego, Llúcia, Ruiz-Hueso, Paula, Ruiz-Roldán, Lidia, Torres-Puente, Manuela, Alberola, Juan, Albert, Eliseo, Aranzamendi Zaldumbide, Maitane, Bea-Escudero, María Pilar, Boga, Jose Antonio, Bordoy, Antoni E., Canut-Blasco, Andrés, Carvajal, Ana, Cilla Eguiluz, Gustavo, Cordón Rodríguez, Maria Luz, Costa-Alcalde, José J., de Toro, María, de Toro Peinado, Inmaculada, del Pozo, Jose Luis, Duchêne, Sebastián, Fernández-Pinero, Jovita, Fuster Escrivá, Begoña, Gimeno Cardona, Concepción, González Galán, Verónica, Gonzalo Jiménez, Nieves, Hernáez Crespo, Silvia, Herranz, Marta, Lepe, José Antonio, López-Causapé, Carla, López-Hontangas, José Luis, Martín, Vicente, Martró, Elisa, Milagro Beamonte, Ana, Montes Ros, Milagrosa, Moreno-Muñoz, Rosario, Navarro, David, Navarro-Marí, José María, Not, Anna, Oliver, Antonio, Palop-Borrás, Begoña, Parra Grande, Mónica, Pedrosa-Corral, Irene, Pérez González, Maria Carmen, Pérez-Lago, Laura, Pérez-Ruiz, Mercedes, Piñeiro Vázquez, Luis, Rabella, Nuria, Rezusta, Antonio, Robles Fonseca, Lorena, Rodríguez-Villodres, Ángel, Sanbonmatsu-Gámez, Sara, Sicilia, Jon, Soriano, Alex, Tirado Balaguer, María Dolores, Torres, Ignacio, Tristancho, Alexander, Marimón, José María, Pérez-Tur, Jordi, Catalán-Alonso, Pilar, Suárez González, Julia, Muñoz, Patricia, Ruiz-Rodríguez, Paula, Bracho, María Alma, Martínez Priego, Llúcia, Galán-Vendrell, Inmaculada, De Marco, Griselda, Ferrús-Abad, María Loreto, Carbó-Ramírez, Sandra, Nogueira, Jose Miguel, Camarena, Juan José, Martínez Expósito, Óscar, Antona Urieta, Nerea, Castelló-Abietar, Cristian, Rojo-Alba, Susana, Álvarez-Argüelles, Marta Elena, Melón, Santiago, Antuori, Adrián, Fernández-Navarro, Anabel, Lecaroz Agara, Maria Concepción, Gómez-González, Carmen, Aguirre-Quiñonero, Amaia, López-Mirones, José Israel, Fernández-Torres, Marina, Almela-Ferrer, Maria Rosario, Fregeneda-Grandes, Juan Miguel, Argüello, Héctor, Sorarrain, Ane, Trastoy, Rocío, Barbeito Castiñeiras, Gema, Coira, Amparo, Pérez del Molino, María Luisa, Aguilera, Antonio, Mediavilla Gradolph, Maria Concepción, Fernández-Alonso, Mirian, González-Recio, Oscar, Gutiérrez-Rivas, Mónica, Jiménez Clavero, Miguel Ángel, Ocete Mochón, María Dolores, Medina-Gonzalez, Rafael, Reina, Jordi, Gómez-Ruiz, Maria Dolores, Gonzalez-Barbera, Eva M., Molina, Antonio J., Fernandez-Villa, Tania, Martínez-Cameo, Nieves Felisa, Gracia-Grataloup, Yolanda, Tirado Balaguer, Maria Dolores, Gómez Alonso, Bárbara, Arjona Zaragozí, Francisco José, Chamizo López, Francisco Javier, Bordes-Benítez, Ana, Rabella, Núria, Navarro, Ferran, Miró, Elisenda, Simarro Córdoba, Encarnación, Lozano-Serra, Julia, Soriano, Álex, Roig Sena, Francisco Javier, Vanaclocha Luna, Hermelinda, Sanmartín, Isabel, García-Souto, Daniel, Pequeño-Valtierra, Ana, Tubio, Jose M. C., Temes, Javier, Rodríguez-Castro, Jorge, Santamarina García, Martín, Rodríguez-Iglesias, Manuel, Galán-Sanchez, Fátima, Rodríguez-Pallares, Salud, Azcona-Gutiérrez, José Manuel, Blasco-Alberdi, Miriam, Mayor, Alfredo, García-Basteiro, Alberto L., Moncunill, Gemma, Dobaño, Carlota, Cisteró, Pau, Mitjà, Oriol, González-Beiras, Camila, Vall-Mayans, Martí, Corbacho-Monné, Marc, Alemany, Andrea, Muñoz-Cuevas, Cristina, Rodríguez-Rodríguez, Guadalupe, Benito, Rafael, Algarate, Sonia, Bueno, Jessica, Vergara-Gómez, Andrea, Martínez, Miguel J., Vila, Jordi, Rubio, Elisa, Peiró-Mestres, Aida, Navero-Castillejos, Jessica, Posada, David, Valverde, Diana, Estévez, Nuria, Fernández-Silva, Iria, de Chiara, Loretta, Gallego-García, Pilar, Varela, Nair, Gómez-Pinedo, Ulises, Gozalo-Margüello, Mónica, Cano García, Maria Eliecer, Méndez-Legaza, José Manuel, Rodríguez-Lozano, Jesus, Siller, María, Pablo-Marcos, Daniel, Ruiz-García, Maria Montserrat, Galiana, Antonio, Sánchez-Almendro, Judith, Gascón Ros, Maria Isabel, Torregrosa-Hetland, Cristina Juana, Pastor Boix, Eva María, Cascales Ramos, Paloma, Garcinuño Enríquez, Pedro Luis, Raga Borja, Salvador, González Cantó, Julia, Martínez Macias, Olalla, de Salazar, Adolfo, Viñuela González, Laura, Chueca, Natalia, García, Federico, Gómez-Camarasa, Cristina, Farga Martí, Amparo, Falcón, Rocío, Domínguez-Márquez, Victoria, Planas, Anna M., Fernández-Cádenas, Israel, Marcos, Maria Ángeles, Ezpeleta, Carmen, Navascués, Ana, Miqueleiz Zapatero, Ana, Segovia, Manuel, Moreno-Docón, Antonio, Viedma, Esther, Recio Martínez, Raúl, Muñoz-Gallego, Irene, Gonzalez-Bodi, Sara, Folgueira, Maria Dolores, Mingorance, Jesús, Dahdouh, Elias, Lázaro-Perona, Fernando, Rodríguez-Tejedor, María, Romero-Gómez, María Pilar, García-Rodríguez, Julio, Galán, Juan Carlos, Rodríguez-Dominguez, Mario, Martínez-García, Laura, Abreu Di Berardino, Melanie, Ponce-Alonso, Manuel, González-Alba, Jose Maria, Sanz-Muñoz, Ivan, Pérez San José, Diana, Gil Fortuño, Maria, Bellido-Blasco, Juan B., Yagüe Muñoz, Alberto, Hernández Pérez, Noelia, Buj Jordá, Helena, Pérez Olaso, Óscar, González Praetorius, Alejandro, Martínez Ramírez, Nora Mariela, Ramírez Marinero, Aida, Padilla León, Eduardo, Vilas Basil, Alba, Canal Aranda, Mireia, Bernet Sánchez, Albert, Bellés Bellés, Alba, López González, Eric, Prats Sánchez, Iván, García-González, Mercè, Martínez-Lirola, Miguel José, Rodríguez Maresca, Manuel Ángel, Cabezas Fernández, Maria Teresa, Carrillo Gil, María Eugenia, Ventero Martín, Maria Paz, Molina Pardines, Carmen, Orta Mira, Nieves, Navarro Cots, María, Vidal Catalá, Inmaculada, García Nava, Isabel, Illescas Fernández-Bermejo, Soledad, Martínez-Alarcón, José, Torres-Narbona, Marta, Colmenarejo, Cristina, García-Agudo, Lidia, Pérez García, Jorge A., Yago López, Martín, Goberna Bravo, María Ángeles, Simón García, Victoria, Llop Furquet, Gonzalo, Iranzo Tatay, Agustín, Moreno-Marro, Sandra, Lozano Rodríguez, Noelia, Broseta Tamarit, Amparo, Badiola Díez, Juan José, Martínez-Ramírez, Amparo, Dopazo, Ana, Callejas, Sergio, Benguría, Alberto, Aguado, Begoña, Alcamí, Antonio, Bermejo Bermejo, Marta, Ramos-Ruíz, Ricardo, Fernández Soria, Víctor Manuel, Simón Soria, Fernando, Roig Cardells, Mercedes, Coscolla, Mireia, González-Candelas, Fernando, Comas, Iñaki, Instituto de Salud Carlos III, Consejo Superior de Investigaciones Científicas (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Research Council, European Commission, Generalitat Valenciana, Chiner-Oms, Álvaro [0000-0002-0463-0101], Ruiz-Rodríguez, Paula [0000-0003-0727-5974], D'Auria, Giuseppe [0000-0003-0672-2541], Gómez-Navarro, Inmaculada [0000-0002-5235-7365], Jiménez Serrano, Santiago [0000-0003-2917-6053], Aranzamendi Zaldumbide, Maitane [0000-0003-2432-7078], Boga, José Antonio [0000-0002-5500-9972], Bordoy, Antoni E. [0000-0002-1165-542X], Costa-Alcalde, José J. [0000-0002-1916-2216], Toro Peinado, Inmaculada de [0000-0002-8151-3275], López-Causapé, Carla [0000-0003-2228-2005], Martín, Vicente [0000-0003-0552-2804], Moreno-Muñoz, Rosario [0000-0002-0185-5612], Parra Grande, Mónica [0000-0002-8330-7467], Balaguer, María Dolores [0000-0003-3808-7300], Coscolla, Mireia [0000-0003-0752-0538], González-Candelas, Fernando [0000-0002-0879-5798], Comas, Iñaki [0000-0001-5504-9408], Ministerio de Ciencia (España), Generalitat Valenciana (España), Chiner-Oms, Álvaro, Ruiz-Rodríguez, Paula, D'Auria, Giuseppe, Gómez-Navarro, Inmaculada, Jiménez Serrano, Santiago, Aranzamendi Zaldumbide, Maitane, Boga, José Antonio, Bordoy, Antoni E., Costa-Alcalde, José J., Toro Peinado, Inmaculada de, López-Causapé, Carla, Martín, Vicente, Moreno-Muñoz, Rosario, Parra Grande, Mónica, Balaguer, María Dolores, Coscolla, Mireia, González-Candelas, Fernando, Comas, Iñaki, and Marimon, Jose Maria

Subjects
DYNAMICS, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Physical Distancing, Biology, Severity of Illness Index, Article, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, Pandemic, Quarantine, Genetics, Humans, Clade, Phylogeny, 030304 developmental biology, 0303 health sciences, Models, Statistical, SARS-CoV-2, Incidence (epidemiology), Incidence, Genetic variants, COVID-19, Genomics, New variant, Dynamics, Virus, 3. Good health, Spain, Communicable Disease Control, VIRUS, 030217 neurology & neurosurgery, Demography
Abstract

SeqCOVID-Spain consortium: Álvaro Chiner-Oms, Irving Cancino-Muñoz, Mariana G. López, Manuela Torres-Puente, Inmaculada Gómez-Navarro, Santiago Jiménez-Serrano, Jordi Pérez-Tur, Darío García de Viedma, Laura Pérez-Lago, Marta Herranz, Jon Sicilia, Pilar Catalán-Alonso, Julia Suárez González, Patricia Muñoz, Mireia Coscolla, Paula Ruiz-Rodríguez, Fernando González-Candelas, Iñaki Comas, Lidia Ruiz-Roldán, María Alma Bracho, Neris García-González, Llúcia Martínez Priego, Inmaculada Galán-Vendrell, Paula Ruiz-Hueso, Griselda De Marco, María Loreto Ferrús-Abad, Sandra Carbó-Ramírez, Giuseppe D’Auria, Galo Adrian Goig, Juan Alberola, Jose Miguel Nogueira, Juan José Camarena, David Navarro, Eliseo Albert, Ignacio Torres, Maitane Aranzamendi Zaldumbide, Óscar Martínez Expósito, Nerea Antona Urieta, María de Toro, María Pilar Bea-Escudero, Jose Antonio Boga, Cristian Castelló-Abietar, Susana Rojo-Alba, Marta Elena Álvarez-Argüelles, Santiago Melón, Elisa Martró, Antoni E. Bordoy, Anna Not, Adrián Antuori, Anabel Fernández-Navarro, Andrés Canut-Blasco, Silvia Hernáez Crespo, Maria Luz Cordón Rodríguez, Maria Concepción Lecaroz Agara, Carmen Gómez-González, Amaia Aguirre-Quiñonero, José Israel López-Mirones, Marina Fernández-Torres, Maria Rosario Almela-Ferrer, Ana Carvajal, Juan Miguel Fregeneda-Grandes, Héctor Argüello, Gustavo Cilla Eguiluz, Milagrosa Montes Ros, Luis Piñeiro Vázquez, Ane Sorarrain, José María Marimón, José J. Costa-Alcalde, Rocío Trastoy, Gema Barbeito Castiñeiras, Amparo Coira, María Luisa Pérez del Molino, Antonio Aguilera, Begoña Palop-Borrás, Inmaculada de Toro Peinado, Maria Concepción Mediavilla Gradolph, Mercedes Pérez-Ruiz, Mirian Fernández-Alonso, Jose Luis del Pozo, Oscar González-Recio, Mónica Gutiérrez-Rivas, Jovita Fernández-Pinero, Miguel Ángel Jiménez Clavero, Begoña Fuster Escrivá, Concepción Gimeno Cardona, María Dolores Ocete Mochón, Rafael Medina-Gonzalez, José Antonio Lepe, Verónica González Galán, Ángel Rodríguez-Villodres, Nieves Gonzalo Jiménez, Jordi Reina, Carla López-Causapé, Maria Dolores Gómez-Ruiz, Eva M. Gonzalez-Barbera, José Luis López-Hontangas, Vicente Martín, Antonio J. Molina, Tania Fernandez-Villa, Ana Milagro Beamonte, Nieves Felisa Martínez-Cameo, Yolanda Gracia-Grataloup, Rosario Moreno-Muñoz, Maria Dolores Tirado Balaguer, José María Navarro-Marí, Irene Pedrosa-Corral, Sara Sanbonmatsu-Gámez, Antonio Oliver, Mónica Parra Grande, Bárbara Gómez Alonso, Francisco José Arjona Zaragozí, Maria Carmen Pérez González, Francisco Javier Chamizo López, Ana Bordes-Benítez, Núria Rabella, Ferran Navarro, Elisenda Miró, Antonio Rezusta, Alexander Tristancho, Encarnación Simarro Córdoba, Julia Lozano-Serra, Lorena Robles Fonseca, Álex Soriano, Francisco Javier Roig Sena, Hermelinda Vanaclocha Luna, Isabel Sanmartín, Daniel García-Souto, Ana Pequeño-Valtierra, Jose M. C. Tubio, Javier Temes, Jorge Rodríguez-Castro, Martín Santamarina García, Manuel Rodríguez-Iglesias, Fátima Galán-Sanchez, Salud Rodríguez-Pallares, José Manuel Azcona-Gutiérrez, Miriam Blasco-Alberdi, Alfredo Mayor, Alberto L. García-Basteiro, Gemma Moncunill, Carlota Dobaño, Pau Cisteró, Oriol Mitjà, Camila González-Beiras, Martí Vall-Mayans, Marc Corbacho-Monné, Andrea Alemany, Cristina Muñoz-Cuevas, Guadalupe Rodríguez-Rodríguez, Rafael Benito, Sonia Algarate, Jessica Bueno, Andrea Vergara-Gómez, Miguel J. Martínez, Jordi Vila, Elisa Rubio, Aida Peiró-Mestres, Jessica Navero-Castillejos, David Posada, Diana Valverde, Nuria Estévez, Iria Fernández-Silva, Loretta de Chiara, Pilar Gallego-García, Nair Varela, Ulises Gómez-Pinedo, Mónica Gozalo-Margüello, Maria Eliecer Cano García, José Manuel Méndez-Legaza, Jesus Rodríguez-Lozano, María Siller, Daniel Pablo-Marcos, Maria Montserrat Ruiz-García, Antonio Galiana, Judith Sánchez-Almendro, Maria Isabel Gascón Ros, Cristina Juana Torregrosa-Hetland, Eva María Pastor Boix, Paloma Cascales Ramos, Pedro Luis Garcinuño Enríquez, Salvador Raga Borja, Julia González Cantó, Olalla Martínez Macias, Adolfo de Salazar, Laura Viñuela González, Natalia Chueca, Federico García, Cristina Gómez-Camarasa, Amparo Farga Martí, Rocío Falcón, Victoria Domínguez-Márquez, Anna M. Planas, Israel Fernández-Cádenas, Maria Ángeles Marcos, Carmen Ezpeleta, Ana Navascués, Ana Miqueleiz Zapatero, Manuel Segovia, Antonio Moreno-Docón, Esther Viedma, Raúl Recio Martínez, Irene Muñoz-Gallego, Sara Gonzalez-Bodi, Maria Dolores Folgueira, Jesús Mingorance, Elias Dahdouh, Fernando Lázaro-Perona, María Rodríguez-Tejedor, María Pilar Romero-Gómez, Julio García-Rodríguez, Juan Carlos Galán, Mario Rodríguez-Dominguez, Laura Martínez-García, Melanie Abreu Di Berardino, Manuel Ponce-Alonso, Jose Maria González-Alba, Ivan Sanz-Muñoz, Diana Pérez San José, Maria Gil Fortuño, Juan B. Bellido-Blasco, Alberto Yagüe Muñoz, Noelia Hernández Pérez, Helena Buj Jordá, Óscar Pérez Olaso, Alejandro González Praetorius, Nora Mariela Martínez Ramírez, Aida Ramírez Marinero, Eduardo Padilla León, Alba Vilas Basil, Mireia Canal Aranda, Albert Bernet Sánchez, Alba Bellés Bellés, Eric López González, Iván Prats Sánchez, Mercè García-González, Miguel José Martínez-Lirola, Manuel Ángel Rodríguez Maresca, Maria Teresa Cabezas Fernández, María Eugenia Carrillo Gil, Maria Paz Ventero Martín, Carmen Molina Pardines, Nieves Orta Mira, María Navarro Cots, Inmaculada Vidal Catalá, Isabel García Nava, Soledad Illescas Fernández-Bermejo, José Martínez-Alarcón, Marta Torres-Narbona, Cristina Colmenarejo, Lidia García-Agudo, Jorge A. Pérez García, Martín Yago López, María Ángeles Goberna Bravo, Victoria Simón García, Gonzalo Llop Furquet, Agustín Iranzo Tatay, Sandra Moreno-Marro, Noelia Lozano Rodríguez, Amparo Broseta Tamarit, Juan José Badiola Díez, Amparo Martínez-Ramírez, Ana Dopazo, Sergio Callejas, Alberto Benguría, Begoña Aguado, Antonio Alcamí, Marta Bermejo Bermejo, Ricardo Ramos-Ruíz, Víctor Manuel Fernández Soria, Fernando Simón Soria & Mercedes Roig Cardells, The coronavirus disease 2019 (COVID-19) pandemic has affected the world radically since 2020. Spain was one of the European countries with the highest incidence during the first wave. As a part of a consortium to monitor and study the evolution of the epidemic, we sequenced 2,170 samples, diagnosed mostly before lockdown measures. Here, we identified at least 500 introductions from multiple international sources and documented the early rise of two dominant Spanish epidemic clades (SECs), probably amplified by superspreading events. Both SECs were related closely to the initial Asian variants of SARS-CoV-2 and spread widely across Spain. We inferred a substantial reduction in the effective reproductive number of both SECs due to public-health interventions (Re, This work was mainly funded by the Instituto de Salud Carlos III project COV20/00140, with additional funding by Spanish National Research Council project CSIC-COV19-021, Ministerio de Ciencia project PID2019-104477RB-100, ERC StG 638553 and ERC CoG 101001038 to I.C., and BFU2017-89594R to F.G.C. M.C. is supported by Ramón y Cajal program from Ministerio de Ciencia and grants RTI2018-094399-A-I00 and Generalitat Valenciana (Regional Government) project SEJI/2019/011. We gratefully acknowledge Hospital Universitari Vall d’Hebron, Instituto de Salud Carlos III, IrsiCaixa AIDS Research Lab and all the international researchers and institutions that submitted sequenced SARS-CoV-2 genomes to the GISAID’s EpiCov Database (Supplementary Table 1), as an important part of our analyses has been made possible by the sharing of their work. We also thank Unidad de Bioinformática y Estadística, Centro de Investigación Príncipe Felipe, for allowing us to use the Computer Cluster to perform some of the bioinformatic analysis.

Published
2021

15. Levels of Polychlorinated Dibenzo-p-Dioxins/Furans (PCDD/Fs) and Dioxin-Like Polychlorinated Biphenyls (DL-PCBs) in Human Breast Milk in Chile: A Pilot Study

Author

Foerster, Claudia, primary, Zúñiga-Venegas, Liliana, additional, Enríquez, Pedro, additional, Rojas, Jacqueline, additional, Zamora, Claudia, additional, Muñoz, Ximena, additional, Pancetti, Floria, additional, Muñoz-Quezada, María Teresa, additional, Lucero, Boris, additional, Saracini, Chiara, additional, Salas, Claudio, additional, and Cortés, Sandra, additional

Published
2021
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16. Absent or insufficient anti-SARS-CoV-2 S antibodies at ICU admission are associated to higher viral loads in plasma, antigenemia and mortality in COVID-19 patients

Author

Martin-Vicente, María, primary, Almansa, Raquel, additional, Martínez, Isidoro, additional, Tedim, Ana P., additional, Bustamante, Elena, additional, Tamayo, Luis, additional, Aldecoa, César, additional, Gómez, José Manuel, additional, Renedo, Gloria, additional, Berezo, Jose Ángel, additional, Cedeño, Jamil Antonio, additional, Mamolar, Nuria, additional, Olivares, Pablo García, additional, Herrán, Rubén, additional, Cicuendez, Ramón, additional, Enríquez, Pedro, additional, Ortega, Alicia, additional, Jorge, Noelia, additional, de la Fuente, Amanda, additional, Bustamante-Munguira, Juan, additional, Muñoz-Gómez, María José, additional, González-Rivera, Milagros, additional, Puertas, Carolina, additional, Más, Vicente, additional, Vázquez, Mónica, additional, Pérez-García, Felipe, additional, Rico-Feijoo, Jesús, additional, Martín, Silvia, additional, Motos, Anna, additional, Fernandez-Barat, Laia, additional, Eiros, Jose María, additional, Dominguez-Gil, Marta, additional, Ferrer, Ricard, additional, Barbé, Ferrán, additional, Kelvin, David J, additional, Bermejo-Martin, Jesús F, additional, Resino, Salvador, additional, and Torres, Antoni, additional

Published
2021
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17. Diseño de una metodología para la modelización acústica 3D mediante elementos finitos de dispositivos con monolito en sistemas de escape de vehículos. Aplicación a filtros de partículas diésel

Author

Juárez Enríquez, Pedro Ángel

Subjects
Elements finits, Diesel particulate filter, INGENIERIA MECANICA, Finite elements, Monolito, Índex de pèrdua de transmissió, ANSYS APDL, Monòlit, Sistema d' escapament, ANSYS Workbench, Acústica, Índice de perdida de transmisión, Exhaust system, Elementos finitos, Atenuación sonora, Ecuación de ondas, Equació d'ones, Acoustics, Atenuació sonora, Sound attenuation, Transmission loss index, Máster Universitario en Ingeniería Industrial-Màster Universitari en Enginyeria Industrial, Filtro de partículas diésel, Wave equation, Filtre de partícules dièsel, Sistema de escape, Monolith
Abstract

[ES] El presente Trabajo Fin de Máster se desarrolla en el campo de la acústica, concretamente en el centrado en la modelización de la propagación de ondas sonoras en el interior de los filtros de partículas, que en los últimos años se han desarrollado en el ámbito automovilístico ante el endurecimiento de las leyes reguladoras de las emisiones contaminantes, especialmente en los motores diésel. Pese a tener este enfoque fundamental en su diseño, estos también tienen una influencia no despreciable en el ruido emitido por los motores de combustión. Inicialmente se presentan los fundamentos acústicos básicos, tanto en conductos como en los monolitos de filtros de partículas. Posteriormente se detalla la modelización mediante elementos finitos, basada en un modelo que admite ondas tridimensionales en los conductos y propagación unidimensional en el monolito, esta última más aproximada a la realidad. Para ello se desarrolla una metodología completa de modelización acústica 3D mediante el método de elementos finitos (MEF) en base al programa comercial Ansys, en sus versiones APDL y Workbench. Ello es posible ya que en las últimas versiones se han incorporado mejoras sustanciales en los módulos correspondientes al análisis acústico, proporcionando resultados satisfactorios. El doble enfoque presentado permite una adecuada validación de la metodología. Para mostrar el potencial y versatilidad de la metodología desarrollada, se consideran diferentes tipos de geometrías como pueden ser rectangular, circular o triangular. También se estudiarán los efectos del descentrado del conducto de salida del filtro así como cuatro tipos distintos de monolito. Durante la vida útil del filtro se produce la deposición de hollín en este, haciendo necesaria su regeneración, analizando por lo tanto el efecto del hollín en el ruido emitido, especialmente en el parámetro conocido como índice de perdida de transmisión (TL). Por tanto, con las herramientas desarrolladas se lleva a cabo un estudio exhaustivo de la influencia en la atenuación acústica de parámetros de diseño y funcionamiento del filtro de partículas diésel., [CA] El present Treball Final de Màster es desenvolupa en el camp de l' acústica, concretament en el centrat en la modelització de la propagació d' ones sonores en l'interior del filtres de partícules, que en els darrers anys s'han desenvolupat en l'ambit automobilístic davant l' enduriment de les lleis reguladores de les emissions contaminants, especialment en els motors dièsel. Malgrat tindre aquest enfocament fonamental en el seu disseny, aquests també tenen una influència no menyspreable en el soroll emés pels motors de combustió. Inicialment es presenten els fonaments acústics bàsics, tant en conductes com en els monòlits de filtres de partícules. Posteriorment es detalla la modelització mitjançant elements finits, basada en un model que admet ones tridimensionals en els conductes i propagació unidimensional en el monòlit, aquesta última més aproximada a la realitat. Per a això es desenvolupa una metodologia completa de modelització acústica 3D mitjançant el mètode d'elements finits (MEF) sobre la base del programa comercial Ansys, en les seues versions APDL i Workbench. Això és possible ja que en les últimes versions s'han incorporat millores substancials en els mòduls corresponents a l'anàlisi acústica, proporcionant resultats satisfactoris. El doble enfocament presentat permet una adequada validació de la metodologia. Per a mostrar el potencial i versatilitat de la metodologia desenvolupada, es consideren diferents tipus de geometries com poden ser rectangular, circular o triangular. També s'estudiaran els efectes del descentrat del conducte d'eixida del filtre així com quatre tipus diferents de monòlit. Durant la vida útil del filtre es produeix la deposició de sutge en aquest, fent necessària la seua regeneració, analitzant per tant l'efecte del sutge en el soroll emés, especialment en el paràmetre conegut com a índex de pèrdua de transmissió (TL). Per tant, amb les eines desenvolupades es du a terme un estudi exhaustiu de la influència en l'atenuació acústica de paràmetres de disseny i funcionament del filtre de partícules dièsel., [EN] The present Master's Final Project is developed in the field of acoustics, specifically in the one centred on the modelling of sound wave propagation inside particulate filters, which in recent years has been developed in the automotive field in the face of the hardening of the laws regulating polluting emissions, especially in diesel engines. Despite this fundamental approach in their design, they also have a significant influence on the noise emitted by combustion engines. Initially the basic acoustic fundamentals are presented, both in ducts and in particulate filter monoliths. Subsequently, finite element modelling is detailed, based on a model that admits three-dimensional waves in the ducts and one-dimensional propagation in the monolith, the latter being closer to reality. For this purpose, a complete 3D acoustic modelling methodology is developed using the finite element method (FEM) based on the commercial program Ansys, in its APDL and Workbench versions. This is possible because in the latest versions substantial improvements have been incorporated in the modules corresponding to the acoustic analysis, providing satisfactory results. The double approach presented allows for an adequate validation of the methodology To show the potential and versatility of the developed methodology, different types of geometries such as rectangular, circular or triangular are considered. The effects of the offset of the filter outlet duct will also be studied, as well as four different types of monolith. During the life of the filter, soot is deposited on it, making its regeneration necessary. Therefore, the effect of soot on the emitted noise will be analyzed, especially on the parameter known as transmission loss index (TL). Therefore, with the tools developed, an exhaustive study of the influence on the acoustic attenuation of design and operating parameters of the diesel particulate filter is carried out.

Published
2020

18. Additional file 3 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Abstract

Additional file 3. Multivariate logistic regression analysis comparing outpatients against wards patients (backward stepwise selection method/Likelihood Ratio). The association between viral RNAemia with hospitalization at the wards was evaluated adjusting by major confounding factors, but it was not selected in the final model.

Published
2020
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19. Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients.

Author

Martin‐Vicente, María, Almansa, Raquel, Martínez, Isidoro, Tedim, Ana P., Bustamante, Elena, Tamayo, Luis, Aldecoa, César, Gómez, José Manuel, Renedo, Gloria, Berezo, Jose Ángel, Cedeño, Jamil Antonio, Mamolar, Nuria, García Olivares, Pablo, Herrán‐Monge, Rubén, Cicuendez, Ramón, Enríquez, Pedro, Ortega, Alicia, Jorge, Noelia, Doncel, Cristina, and de la Fuente, Amanda

Subjects
COVID-19, VIRAL antibodies, IMMUNOGLOBULINS, MORTALITY, VIRAL replication
Abstract

Background: Anti‐SARS‐CoV‐2 S antibodies prevent viral replication. Critically ill COVID‐19 patients show viral material in plasma, associated with a dysregulated host response. If these antibodies influence survival and viral dissemination in ICU‐COVID patients is unknown. Patients/Methods: We studied the impact of anti‐SARS‐CoV‐2 S antibodies levels on survival, viral RNA‐load in plasma, and N‐antigenaemia in 92 COVID‐19 patients over ICU admission. Results: Frequency of N‐antigenaemia was >2.5‐fold higher in absence of antibodies. Antibodies correlated inversely with viral RNA‐load in plasma, representing a protective factor against mortality (adjusted HR [CI 95%], p): (S IgM [AUC ≥ 60]: 0.44 [0.22; 0.88], 0.020); (S IgG [AUC ≥ 237]: 0.31 [0.16; 0.61], <0.001). Viral RNA‐load in plasma and N‐antigenaemia predicted increased mortality: (N1‐viral load [≥2.156 copies/ml]: 2.25 [1.16; 4.36], 0.016); (N‐antigenaemia: 2.45 [1.27; 4.69], 0.007). Conclusions: Low anti‐SARS‐CoV‐2 S antibody levels predict mortality in critical COVID‐19. Our findings support that these antibodies contribute to prevent systemic dissemination of SARS‐CoV‐2. [ABSTRACT FROM AUTHOR]

Published
2022
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20. SARS-CoV-2 RNA viremia is associated with a sepsis-like host response and critical illness in COVID-19

Author

Bermejo-Martin, Jesús F, primary, González-Rivera, Milagros, additional, Almansa, Raquel, additional, Micheloud, Dariela, additional, Domínguez-Gil, Marta, additional, Resino, Salvador, additional, Martín-Fernández, Marta, additional, Murua, Pablo Ryan, additional, Pérez-García, Felipe, additional, Tamayo, Luis, additional, Lopez-Izquierdo, Raúl, additional, Bustamante, Elena, additional, Aldecoa, César, additional, Gómez, José Manuel, additional, Rico-Feijoo, Jesús, additional, Orduña, Antonio, additional, Méndez, Raúl, additional, Natal, Isabel Fernández, additional, Megías, Gregoria, additional, González-Estecha, Montserrat, additional, Carriedo, Demetrio, additional, Doncel, Cristina, additional, Jorge, Noelia, additional, del Campo, Félix, additional, Fernández-Ratero, José Antonio, additional, Trapiello, Wysali, additional, González-Jiménez, Paula, additional, Ruiz, Guadalupe, additional, Kelvin, Alyson A., additional, Ostadgavahi, Ali Toloue, additional, Oneizat, Ruth, additional, Ruiz, Luz María, additional, Miguéns, Iria, additional, Gargallo, Esther, additional, Muñoz, Ioana, additional, Pelegrin, Sara, additional, Martín, Silvia, additional, Olivares, Pablo García, additional, Cedeño, Jamil Antonio, additional, Albi, Tomás Ruiz, additional, Puertas, Carolina, additional, Berezo, Jose Ángel, additional, Renedo, Gloria, additional, Herrán, Rubén, additional, Bustamante-Munguira, Juan, additional, Enríquez, Pedro, additional, Cicuendez, Ramón, additional, Blanco, Jesús, additional, Abadia, Jesica, additional, Barquero, Julia Gómez, additional, Mamolar, Nuria, additional, Blanca-López, Natalia, additional, Valdivia, Luis Jorge, additional, Caso, Belén Fernández, additional, Mantecón, María Ángeles, additional, Motos, Anna, additional, Fernandez-Barat, Laia, additional, Ferrer, Ricard, additional, Barbé, Ferrán, additional, Torres, Antoni, additional, Menéndez, Rosario, additional, Eiros, José María, additional, and Kelvin, David J, additional

Published
2020
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24. Estudio de la influencia de la temperatura en el proceso de medida de tasa de inyección diesel

Author

Juárez Enríquez, Pedro Ángel

Subjects
Injection system, Sistema de inyección, MAQUINAS Y MOTORES TERMICOS, Intercambiador de calor, diesel injector, Heat exchanger, INGENIERIA AEROESPACIAL, Inyector diesel, Grado en Ingeniería en Tecnologías Industriales-Grau en Enginyeria en Tecnologies Industrials
Abstract

[ES] La caracterización hidráulica de un inyector es fundamental para comprender su funcionamiento. Para conocer su comportamiento bajo los regímenes de operación deseados hace falta controlar correctamente las condiciones en las cuales trabaja. El objetivo del presente trabajo es hacer el diseño y montaje de un dispositivo que funciona como un intercambiador de calor, diseñado para mantener las temperaturas, tanto del inyector como del combustible dentro del tasímetro, a los niveles deseados para medir la tasa de inyección de dicho inyector. Se utilizarán herramientas computarizadas y medidas experimentales para comparar el efecto que tiene este sistema sobre el control de la temperatura y sobre la tasa de inyección., [EN] The hydraulic characterization of an injector is fundamental to understand its operation. In order to know its behavior under the desired operating regimes, it is necessary to correctly control the conditions in which it works. The objective of this paper is to design and assemble a device that works as a heat exchanger, designed to maintain the temperatures of both the injector as the fuel inside the tasimeter, at the desired levels to measure the injection rate of said injector. Computerized tools and experimental measures will be used to compare the eect that this system has on the control of temperature and on the rate of injection.

Published
2018

26. PROPUESTA DIDÁCTICA PARA EL ESTUDIO Y ANÁLISIS ENERGÉTICO DEL RECURSO EÓLICO.

Author

Peredia, Oscar Jesús Guevara, López, Jesús Adán Fierro, Páez, Jesús Gonzalo Valenzuela, Ibarra Enríquez, Pedro, Hernández, Néstor Daniel Galán, and Guillén, Eber Enrique Orozco

Abstract

Copyright of Congreso Internacional de Investigacion Academia Journals is the property of PDHTech, LLC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

32. Evaluación de programas y elementos para la mejora del diseño y desarrollo de la formación inicial de los docentes en metodología de la investigación

Author

Enríquez, Pedro Gegorio, Universitat Autònoma de Barcelona. Departament de Pedagogia Aplicada, Edifici B, 08193 Bellaterra (Cerdanyola del Vallès), Teléfono: 93 5811620, Fax: 93 5813052, Correo electrónico: d.ped.aplicada@uab.es, and Tejada Fernández, José

Subjects
metodología, Argentina, Universidad Nacional de San Luis (Argentina), estudio de casos, cuestionario, programa de formación, evaluación, entrevista, formación inicial
Abstract

Valorar tres programas de formación inicial en metodología de la investigación. Discursos escritos obtenidos mediante la recolección de documentos y discursos obtenidos de los sujetos involucrados en los programas de formación. La evaluación de programas emplea el estudio de caso como estrategia. Se pudo advertir que los enfoques sobre la formación docente y la investigación educativa gravitan en los programas de formación. Asimismo, las dificultades detectadas tanto en planes y programas de estudio como en el desarrollo y los resultados de las propuestas formativas plantean la necesidad de efectuar modificaciones que transformen profundamente la enseñanza de la metodología de la investigación. Finalmente se aportan elementos sustantivos que permitirán el diseño y el desarrollo de una propuesta pedagógico-didáctica que mejore los programas de formación inicial en esta disciplina. Cataluña ESP

Published
2003

33. Evaluación de programas y elementos para la mejora del diseño y desarrollo de la formación inicial de los docentes en metodología de investigación

Author

Gregorio Enríquez, Pedro, Tejada Fernández, José, and Universitat Autònoma de Barcelona. Departament de Pedagogia Aplicada

Subjects
Ciències Socials, Metodología de la investigación, Evaluación de programas, Formación docente
Abstract

El presente trabajo es una Evaluación de Programas que emplea al "estudio de caso" como una estrategia para valorar tres Programas de Formación inicial en Metodología de la Investigación desarrollada en la Facultad de Ciencias Humanas (FCH), de la Universidad Nacional de San Luis (UNSL) durante el ciclo lectivo correspondiente a 1999. Para efectuar este estudio, se recopilan informaciones provenientes de dos corpus de naturaleza diferente; por un lado, los discursos escritos obtenidos mediante la recolección de documentos que están relacionados con el problema; por el otro, los discursos obtenidos de los sujetos involucrados en los programas de formación mediante entrevistas y cuestionarios.Como resultado de la evaluación efectuada se pudo advertir que los enfoques sobre la formación docente y la investigación educativa gravitan en los programas de formación. Asimismo, las dificultades detectadas tanto en planes y programas de estudio como en el desarrollo y los resultados de las propuestas formativas plantean la necesidad de efectuar modificaciones que transformen profundamente la enseñanza de la metodología de la investigación.Finalmente se aportan elementos sustantivos que permitirán el diseño y el desarrollo de una propuesta pedagógico-didáctica que mejore los programas de formación inicial en esta disciplina., The present work is a Program Evaluation that applies "case study" as a strategy to evaluate three Teacher Training Programs on Research Methodology. It has been carried out at Facultad de Ciencias Humanas, Universidad Nacional de San Luis, Argentina, during 1999. Information coming from two corpuses, different in nature, has been compiled for this work: the written discourse obtained by gathering documents related to the problem, and the discourse of the subjects involved in the experience obtained through interviews and questionnaires.As a result of the evaluation, it can be seen that the approaches to Teacher Training and Educational Research influence the training programs. The difficulties found in both the curricula and syllabuses, as well as in the development and results of the pedagogical experiences, put into evidence the need to transform the teaching of Research Methodology. Finally, substantial aspects concerning the design and development of a pedagogical and didactical proposal are given here in order to improve the Teacher Training Programs.

Published
2002

43. Dynamics of the O(3P) + CH4→OH + CH3Reaction Is Similar To That of a Triatomic Reaction.

Author

Martínez, Rodrigo, Enríquez, Pedro A., Puyuelo, María P., and González, Miguel

Subjects
*MOLECULAR dynamics, *CHEMICAL reactions, *METHANE, *TRAJECTORIES (Mechanics), *POTENTIAL energy surfaces, *CHEMISTRY experiments, *PHASE transitions
Abstract

The O(3P) + CH4reaction has beeninvestigatedusing the quasi-classical trajectory (QCT) method and an abinitiopseudotriatomic potential energy surface (PES). Thishas been mainly motivated by very recent experiments which supportthe reliability of the triatomic modeling even at high collision energy(⟨Ecol⟩ = 64 kcal mol–1). The QCT results agree rather well with the experiments(translational and angular distributions of products); i.e., the ab initiopseudotriatomic modeling “captures”the essence of the reaction dynamics, although the PES was not optimizedfor high Ecol. Furthermore, similar experimentson the O(3P) + CD4reaction at moderate Ecol(12.49 kcal mol–1) havealso been of a large interest here and, under these softer reactionconditions, the QCT method leads to results which are almost in quantitativeagreement with experiments. The utility of the ab initiopseudotriatomic modeling has also been recognized for other analogoussystems (X + CH4) but with very different PESs. [ABSTRACT FROM AUTHOR]

Published
2012
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45. Influence of collision energy on the dynamics of the reaction O(1D) + CH<SUB>4</SUB>(X1A<SUB>1</SUB>) → OH(X 2Π) + CH<SUB>3</SUB>(X 2A<SUB>2</SUB>")

Author

Sayós, R., Hernando, Jordi, Puyuelo, María P., Enríquez, Pedro A., and González, Miguel

Abstract

We studied the effects of collision energy (ET) on the dynamics of the title reaction using the quasiclassical trajectory method on an analytical triatomic potential energy surface that we had derived for this system. We compared the dependence of the scalar and two-vector properties of the reaction on ET with experimental data and obtained a quite good agreement. The results can be explained in terms of the coexistence of two microscopic reaction mechanisms: insertion and abstraction. The former mechanism is the most important one, although the contribution of the latter increases with ET .

Published
2002

46. Additional file 4 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 4. Multivariate logistic regression analysis comparing wards patients against ICU patients (backward stepwise selection method/Likelihood Ratio). The association between viral RNAemia and viral RNA load with critical illness was evaluated adjusting by major confounding factors.

47. Additional file 1 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 1. Recruited patients in each hospital.

48. Additional file 2 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 2. Multivariate logistic regression analysis comparing outpatients against wards patients (Enter method). The association between viral RNAemia with hospitalization at the wards was evaluated adjusting by major confounding factors.

49. Additional file 1 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 1. Recruited patients in each hospital.

50. Additional file 5 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 5. Laboratory parameters levels across groups.

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