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14. Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity

Author

Shi, Hao, Munk, Alexander, Nielsen, Thomas S., Daughtry, Morgan R., Larsson, Louise, Li, Shize, Høyer, Kasper F., Geisler, Hannah W., Sulek, Karolina, Kjøbsted, Rasmus, Fisher, Taylor, Andersen, Marianne M., Shen, Zhengxing, Hansen, Ulrik K., England, Eric M., Cheng, Zhiyong, Højlund, Kurt, Wojtaszewski, Jørgen F.P., Yang, Xiaoyong, Hulver, Matthew W., Helm, Richard F., Treebak, Jonas T., and Gerrard, David E.

Published
2018
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24. In-Person Second Look During a Residency Virtual Interview Season: An Important Consideration for Radiology Residency Applicants.

Author

England, Eric, Kanfi, Alisa, and Tobler, Juliana

Abstract

The transition to an all-virtual residency interview process, in response to the COVID-19 pandemic, has seen numerous benefits beyond applicant and program safety. These benefits include improvements in equity, access and even lowering the applicant's carbon footprint. However, a significant portion of applicants have concerns with being unable to visit a program and interact with residents and faculty in person. A second look opportunity for radiology residency applicants was developed to address applicant concerns while maintaining an equitable interview process for all. The second look opportunity took place after our program's final rank list was completed. Second look attendees completed a 10-question online survey after completion of our program's second look to ascertain financial obstacles of attending, the importance of a second look opportunity, and reasons why applicants chose to attend. 24/24 (100%) of attendees completed the survey. The majority of attendees were from >100 miles away (54%). Only 21% felt that the financial burden of the second look was substantial. However, this response was more common among attendees from >100 miles away (p = 0.013). All applicants surveyed chose to attend the second look in order to see the radiology department facilities and to meet the faculty in person. All applicants agreed or strongly agreed that they learned more about the residency program through in-person discussions with residents and faculty than they were able to remotely and that the in-person second look opportunity is a valuable tool to help make an informed rank decision when interviewing virtually. The second look opportunity offers multiple benefits for applicants to help make an informed rank list decision during a virtual interview season. [ABSTRACT FROM AUTHOR]

Published
2023
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26. List of Contributors

Author

Ahn, Dong U., primary, Andueza, Donato, additional, Basu, Lopa, additional, Champomier-Vergès, Marie-Christine, additional, Dasenaki, Marilena E., additional, England, Eric M., additional, Faustman, Cameron, additional, Feng, Xi, additional, Flores, Mónica, additional, Fontanesi, Luca, additional, Gehring, Kerri B., additional, Gerrard, David E., additional, Hocquette, Jean-François, additional, Hopkins, David L., additional, Kerry, Joe P., additional, Lianou, Alexandra, additional, López-Bote, Clemente, additional, Matarneh, Sulaiman K., additional, McGee, Mark, additional, Mendonça, Aubrey F., additional, Miller, Rhonda K., additional, Moloney, Aidan P., additional, Mourot, Benoît-Pierre, additional, Mourot, Jacques, additional, Nychas, George-John E., additional, Ockerman, Herbert W., additional, Panagou, Efstathios Z., additional, Purslow, Peter P., additional, Savell, Jeffrey W., additional, Scheffler, Tracy L., additional, Suman, Surendranath P., additional, Thomaidis, Nikolaos S., additional, Toldrá, Fidel, additional, Tyuftin, Andrey A., additional, Warner, Robyn D., additional, Wood, Jeffrey D., additional, Xiong, Youling L., additional, and Zagorec, Monique, additional

Published
2017
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39. Imaging of scatterers on microwave antenna test ranges

Author

Seville, Andrew, Cook, Gregory G., Bennett, John C., and England, Eric H.

Subjects
Synthetic aperture radar -- Research, Microwave antennas -- Research, Electromagnetic waves -- Scattering, Business, Computers, Electronics, Electronics and electrical industries
Abstract

A circular synthetic aperture imaging technique for evaluating the performance of antenna far-field test ranges is presented. Using multifrequency data, the fields incident on the region occupied by the scanning antenna are used to produce microwave images showing the distribution and level of scattering artifacts on the test site. Results are presented for S- and X-band ranges on a large outdoor antenna measurement facility. Various primary scatterers are identified, together with a source of secondary illumination of scattering objects.

Published
1995

43. The effects of age, sex, and hot carcass weight on cooked lamb flavor and off-flavor in four muscle cuts.

Author

Garza, Horacio, Jaborek, Jerad R, Zerby, Henry N, Moeller, Steven J, Wick, Macdonald P, Fluharty, Francis L, England, Eric M, and Garcia, Lyda G

Subjects
LAMBS, ANIMAL breeding, ERECTOR spinae muscles, LAMB carcasses, ANIMAL carcasses
Abstract

The present study used 48 lambs originating from three different locations in the Western United States (16 lambs per location; 8 ewes and 8 wethers per location). Each consisting of similar breed composition (Suffolk cross) that were selected to represent weight by age at harvest treatments: light weight carcasses at 5 mo (LW5 , 31.81 ± 1.88 kg), light weight carcasses at 12 mo (LW12 , 35.09 ± 4.45 kg), heavy weight carcasses at 12 mo (HW12 , 57.89 ± 4.70 kg) with different carcass weight compositions. Older heavy weight lambs (HW12) had greater (P ≤ 0.01) hot carcass weight, ribeye area, backfat and body wall thickness, and yield grade compared with light weight lamb carcasses (LW5 and LW12). The longissimus thoracis longissimus thoracis (LT) from older lamb carcasses (LW12 and HW12) had a greater (P ≤ 0.01) total lipid percentage compared with younger lamb carcasses (LW5). Across harvest weight and age treatments, wether carcasses had greater (P ≤ 0.05) total lipid percentage compared with ewe carcasses. Slice shear force values were greater (P ≤ 0.01) for both the LT and semimembranosus from older lambs (LW12 and HW12) compared with LW5 lambs, with no differences between ewes and wethers. Lamb flavor intensity was greater (P ≤ 0.05) for the LT of LW12 lambs and tended (P = 0.08) to be greater for HW12 lambs, compared with the LT from LW5 lambs. The off-flavor intensity of the LT was greater (P ≤ 0.01) for older lambs (LW12 and HW12) compared with LW5 lambs. Interestingly, the lamb flavor and off-flavor intensity scores of the ground shoulder exhibited a treatment × sex interaction. Lamb flavor intensity of LW12 lamb was greater (P ≤ 0.05) from ewes compared with wethers, whereas wethers had a greater (P ≤ 0.05) lamb flavor intensity compared with ewes for HW12 lambs, and LW12 ewe lambs had a greater (P ≤ 0.05) off-flavor intensity compared with all other treatment × sex treatment combinations. Overall, lambs in the present study possessed a mild lamb flavor, typically with greater lamb flavor and off-flavor intensities for older animals; while slice shear force and LT lipid percentage increased as animal age increased at the time of harvest. [ABSTRACT FROM AUTHOR]

Published
2021
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47. Best Practices From the APDR

Author

Goldman, Daryl T., primary, Peters, Gail L., additional, Fischman, Aaron M., additional, Vatakencherry, George G., additional, Bream, Peter R., additional, Martin, Jonathan G., additional, Newsome, Janice M., additional, Bercu, Zachary L., additional, Schacht, Michael A., additional, Johnson, Karen S., additional, Milburn, James M., additional, Ong, Seng, additional, Kalia, Vivek, additional, England, Eric, additional, and Heitkamp, Darel E., additional

Published
2018
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48. Presence of oxygen and mitochondria in skeletal muscle early postmortem

Author

England, Eric M., primary, Matarneh, Sulaiman K., additional, Mitacek, Rachel M., additional, Abraham, Anupam, additional, Ramanathan, Ranjith, additional, Wicks, Jordan C., additional, Shi, Hao, additional, Scheffler, Tracy L., additional, Oliver, Emily M., additional, Helm, Emma T., additional, and Gerrard, David E., additional

Published
2018
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50. Postmortem metabolism in porcine skeletal muscle

Author

England, Eric M., Animal and Poultry Sciences, Gerrard, David E., Sobrado, Pablo, Rhoads, Robert P., and Puolanne, T. Eero J.

Subjects
mitochondria, pork quality, skeletal muscle, ultimate pH, AMPK γ3R200Q
Abstract

Once an animal is harvested for meat, skeletal muscle attempts to maintain ATP at or near antemortem levels. To maintain ATP levels postmortem, stored glycogen is catabolized to produce ATP through glycolysis and possibly oxidative metabolism. Hydrolysis of the produced ATP acidifies muscle until an ultimate pH is reached. The ultimate pH of meat directly impacts the quality characteristics of color, texture, and water holding capacity. Therefore, our research intends to describe the contributions glycolysis and oxidative metabolism play in determining ultimate pH and fresh meat quality. Traditionally, glycogen content at death was thought to be responsible for dictating ultimate pH. This was especially true in oxidative muscle with limited glycogen stores. Yet, our research indicated that in the presence of excess glycogen, oxidative muscle maintains a high ultimate pH. Rather, pH inactivation of phosphofructokinase is responsible for terminating postmortem glycolysis and brackets ultimate pH between 5.9 – 5.5. Meat with a pH below this range is uncommon. However, AMPK γ3R200Q mutant pigs produce meat with an ultimate pH near 5.3. Due to lower AMP deaminase abundance in their muscle, AMP levels are elevated late postmortem. Because AMP is a potent activator of phosphofructokinase, the aberrant meat quality from AMPK γ3R200Q mutant pigs is caused by extended postmortem glycolysis. Combined, these data further our understanding of the factors that contribute to the formation of fresh meat quality. We also characterized AMPK γ3R200Q muscle by investigating antemortem skeletal muscle lactate transport. Lactate is transported in or out of tissues by proton-linked iii monocarboxylate transporters (MCTs). Previous reports indicated that acute activation of AMPK increased monocarboxylate transporter expression in skeletal muscle of other species. Yet, it was unknown the impact chronic activation of AMPK will have on MCT1, MCT2, and MCT4 expression in pigs. Compared to wild-type pigs, the longissimus lumborum of AMPK γ3R200Q pigs increased both MCT2 and MCT4 protein expression. Our data suggest glycolytic skeletal muscle from the AMPK γ3R200Q pigs has increased capacity for antemortem lactate export from muscle and possibly increased pyruvate transport into the mitochondria. Ph. D.

Published
2015

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