Search

Purpose: The aim of this study was to investigate the effect of obesity on various ocular examination parameters in a comparative analysis between normal-weight and obese adults. Methods: Thirty-two normal-weight and 64 obese adults were included in the study. Detailed ophthalmologic examination, including intraocular pressure (IOP), central corneal thickness (CCT), keratometry, anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) by A-mode ocular ultrasonography; and macular and retinal nerve fiber layer thickness (RNFL) by spectral domain optical coherence tomography were compared between normal-weight and obese adults. Obese individuals were further stratified into Class I-II and Class III obesity categories, and the ocular parameters were compared between these three groups. Results: IOP was significantly higher in the obese group than in the healthy controls (16.7±2.4 vs. 15.1±2.2 mmHg, p=0.002), whereas CCT, keratometry values, ACD, LT, AL, and RNFL thicknesses did not differ between the groups. The mean retinal thicknesses in the inner retinal ring (3 mm) at superior (p=010), nasal (p=0.04), and temporal (p=0.002) quadrants were lower in the class III obese group compared to class I obese individuals. ACD was significantly narrower in class III obese group (p=0.01). Body mass index was significantly correlated with IOP (p<0.001). Conclusion: Obesity is associated with elevated IOP and signs of retinopathy. An increase in the severity of obesity was found to be associated with a decrease in macular thickness and a narrowing of the anterior chamber. [ABSTRACT FROM AUTHOR]

Aim: This study aims to assess the influence of a newly developed pupil-optimized multifocal soft contact lens (MFSCL) in comparison to single-vision contact lenses (SVCL) on visual performance among adolescent myopes. Materials and Methods: Myopic adolescents, aged 14 to 18 years, who were habitual SVCL users, were subjected to a trial involving MFSCL with a mid-addition power. Various visual parameters including distance and near visual acuity (VA), maximum reading speed (MRS), reading acuity, contrast sensitivity, and stereoacuity under photopic conditions were measured for MFSCL and compared to SVCL. Results: No statistically significant differences were observed between SVCL and MFSCL in terms of near VA, MRS, contrast sensitivity, and stereoacuity (p>0.05 for all). However, a decrease in distance VA was noted with MFSCL (p = 0.021). Moreover, reading acuity, which denotes the smallest print size comprehensible without significant errors, was found to be smaller when using MFSCL (p<0.001). Conclusion: In adolescent myopic patients, mid-add power in MFSCL did not significantly impact near VA and contrast sensitivity when compared to SVCL, while a decrease in distance VA was observed. Moreover, MFSCL did not affect reading speed but did enable the reading of smaller font sizes. [ABSTRACT FROM AUTHOR]

Aim: Upper eyelid blepharoplasty (ULB) is a prevalent aesthetic and functional surgery. This study aims to compare the post-operative dry eye syndrome (DES) symptoms and related diagnostic tests between the patients who underwent ULB with or without fat excision. Materials and Methods: A total of 44 patients (22 with fat excision, 22 without) were evaluated preoperatively and post-operatively in the 1st and 6th months for DES parameters (Schirmer I, tear break-up time, and corneal staining score) and Ocular Surface Disease Index (OSDI) score. Results: Patients undergoing ULB regardless of fat excision demonstrated favorable outcomes in both objective DES tests and subjective DES scale in the postoperative 6th month. There was no significant difference between the two surgical groups in terms of DES parameters in both the 1st and 6th months. Conclusion: ULB appears to ameliorate both objective and subjective manifestations of DES. The inclusion of fat excision during the procedure does not seem to exert a significant effect on these outcomes. [ABSTRACT FROM AUTHOR]

Copyright of Current Retina Journal / Güncel Retina Dergisi is the property of Anadolu Kitabevi Basim Yayim Medikal Turizm Kirtasiye Tic. Ltd. Sti. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Bacillary layer detachment (BALAD) is a relatively new optical coherence tomography (OCT) finding described by the utilization of OCT and characterized by the separation within the photoreceptor inner segment. The most common ocular diseases associated with BALAD include Vogt-Koyanagi-Harada's disease, neovascular age-related macular degeneration, and central serous chorioretinopathy, and it is frequently observed in inflammatory, infectious, traumatic, and mass lesions of the choroid. It usually has a benign course and can resolve spontaneously or with treatment in a very short time, accompanied by an increase in visual acuity. However, its prognostic significance is still contradictory, as studies with long-term follow-up have shown that BALAD is related with subretinal fibrosis. In this review, the anatomical definition, multimodal imaging findings, course, and prognosis of BALAD in various ocular diseases are discussed. [ABSTRACT FROM AUTHOR]

Background/aim: To investigate the effect of intravitreal golimumab on rabbit retina histopathology. Materials and methods: Sixteen albino New Zealand rabbits were divided into three groups. The right eye of each rabbit in groups I, II, and III received a single intravitreal injection of 5 mg/0.05 mL (6 eyes), 10 mg/0.1 mL (6 eyes), or 20 mg/0.2 mL (4 eyes) golimumab, while left eyes served as controls with the same volume of a balanced salt solution injection. All animals were examined using slit-lamp biomicroscopy and indirect ophthalmoscopy before and after intravitreal injection and at days 1 and 7. Animals were euthanized on day 7 and the eyes were enucleated for immunohistochemistry evaluation and electron microscopic examination of the retinas. Results: For groups I, II, and III, the number of cells in the outer nuclear layer and the inner nuclear layer was decreased compared to those in the control groups. In group I, the percentage of caspase-3 staining of the outer nuclear layer was significantly higher than that in the control. For groups II and III, TUNEL and caspase-3 staining percentages in the outer and inner nuclear layers were found to be significantly higher than those for the control groups. In the ganglion cell layer, for groups I, II, and III, neither TUNEL nor caspase-3 staining percentages showed any significant difference between two groups. No significant dose-dependent relationship was found for increasing doses of golimumab in all layers. Myelin figures and karyorrhexis in the photoreceptor cells were prominent in electron microscopy of the golimumab-injected eyes. Conclusion: Golimumab caused apoptosis in both photoreceptors and bipolar cells of the rabbit retina. Potential retinal toxicity of intravitreal golimumab should be considered if an intravitreal administration is planned. [ABSTRACT FROM AUTHOR]

The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases. [ABSTRACT FROM AUTHOR]