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9. Germline Determinants of Esophageal Adenocarcinoma

Author

Jeon, Alvin, Stratulat, Eugeniu, Zagani, Rachid, Taylor, Martin S., Rickelt, Steffen, Kedrin, Dmitriy, Batra, Anupam, Hashmi, Ardeshir, Nishioka, Norman S., Hur, Chin, Goyal, Lipika, Bazerbachi, Fateh, Zukerberg, Lawrence, Lee, Minyi, Eng, George, Handte-Reinecker, Anna, Deshpande, Vikram S., Yilmaz, Omer H., and Gala, Manish K.

Published
2023
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12. Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment

Author

Hwang, William L., Jagadeesh, Karthik A., Guo, Jimmy A., Hoffman, Hannah I., Yadollahpour, Payman, Reeves, Jason W., Mohan, Rahul, Drokhlyansky, Eugene, Van Wittenberghe, Nicholas, Ashenberg, Orr, Farhi, Samouil L., Schapiro, Denis, Divakar, Prajan, Miller, Eric, Zollinger, Daniel R., Eng, George, Schenkel, Jason M., Su, Jennifer, Shiau, Carina, Yu, Patrick, Freed-Pastor, William A., Abbondanza, Domenic, Mehta, Arnav, Gould, Joshua, Lambden, Conner, Porter, Caroline B. M., Tsankov, Alexander, Dionne, Danielle, Waldman, Julia, Cuoco, Michael S., Nguyen, Lan, Delorey, Toni, Phillips, Devan, Barth, Jaimie L., Kem, Marina, Rodrigues, Clifton, Ciprani, Debora, Roldan, Jorge, Zelga, Piotr, Jorgji, Vjola, Chen, Jonathan H., Ely, Zackery, Zhao, Daniel, Fuhrman, Kit, Fropf, Robin, Beechem, Joseph M., Loeffler, Jay S., Ryan, David P., Weekes, Colin D., Ferrone, Cristina R., Qadan, Motaz, Aryee, Martin J., Jain, Rakesh K., Neuberg, Donna S., Wo, Jennifer Y., Hong, Theodore S., Xavier, Ramnik, Aguirre, Andrew J., Rozenblatt-Rosen, Orit, Mino-Kenudson, Mari, Castillo, Carlos Fernandez-del, Liss, Andrew S., Ting, David T., Jacks, Tyler, and Regev, Aviv

Published
2022
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14. Primary Human Colonic Mucosal Barrier Crosstalk with Super Oxygen-Sensitive Faecalibacterium prausnitzii in Continuous Culture

Author

Zhang, Jianbo, Huang, Yu-Ja, Yoon, Jun Young, Kemmitt, John, Wright, Charles, Schneider, Kirsten, Sphabmixay, Pierre, Hernandez-Gordillo, Victor, Holcomb, Steven J., Bhushan, Brij, Rohatgi, Gar, Benton, Kyle, Carpenter, David, Kester, Jemila C., Eng, George, Breault, David T., Yilmaz, Omer, Taketani, Mao, Voigt, Christopher A., Carrier, Rebecca L., Trumper, David L., and Griffith, Linda G.

Published
2021
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15. Supplementary Figure 6 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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16. Supplementary Figure 24 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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17. Supplementary Figure 5 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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18. Supplementary Figure 17 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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19. Supplementary Tables S1-S12 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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20. Supplementary Figure 9 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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21. Supplementary Figure 7 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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22. Supplementary Data 1 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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23. Data from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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24. Supplementary Figure 4 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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25. Supplementary Data 2 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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26. Supplementary Figure 8 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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27. Supplementary Figure 3 from Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker

Author

Taylor, Martin S., primary, Wu, Connie, primary, Fridy, Peter C., primary, Zhang, Stephanie J., primary, Senussi, Yasmeen, primary, Wolters, Justina C., primary, Cajuso, Tatiana, primary, Cheng, Wen-Chih, primary, Heaps, John D., primary, Miller, Bryant D., primary, Mori, Kei, primary, Cohen, Limor, primary, Jiang, Hua, primary, Molloy, Kelly R., primary, Chait, Brian T., primary, Goggins, Michael G., primary, Bhan, Irun, primary, Franses, Joseph W., primary, Yang, Xiaoyu, primary, Taplin, Mary-Ellen, primary, Wang, Xinan, primary, Christiani, David C., primary, Johnson, Bruce E., primary, Meyerson, Matthew, primary, Uppaluri, Ravindra, primary, Egloff, Ann Marie, primary, Denault, Elyssa N., primary, Spring, Laura M., primary, Wang, Tian-Li, primary, Shih, Ie-Ming, primary, Fairman, Jennifer E., primary, Jung, Euihye, primary, Arora, Kshitij S., primary, Yilmaz, Osman H., primary, Cohen, Sonia, primary, Sharova, Tatyana, primary, Chi, Gary, primary, Norden, Bryanna L., primary, Song, Yuhui, primary, Nieman, Linda T., primary, Pappas, Leontios, primary, Parikh, Aparna R., primary, Strickland, Matthew R., primary, Corcoran, Ryan B., primary, Mustelin, Tomas, primary, Eng, George, primary, Yilmaz, Ömer H., primary, Matulonis, Ursula A., primary, Chan, Andrew T., primary, Skates, Steven J., primary, Rueda, Bo R., primary, Drapkin, Ronny, primary, Klempner, Samuel J., primary, Deshpande, Vikram, primary, Ting, David T., primary, Rout, Michael P., primary, LaCava, John, primary, Walt, David R., primary, and Burns, Kathleen H., primary

Published
2024
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28. Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker

Author

Taylor, Martin S., primary, Wu, Connie, additional, Fridy, Peter C., additional, Zhang, Stephanie J., additional, Senussi, Yasmeen, additional, Wolters, Justina C., additional, Cajuso, Tatiana, additional, Cheng, Wen-Chih, additional, Heaps, John D., additional, Miller, Bryant D., additional, Mori, Kei, additional, Cohen, Limor, additional, Jiang, Hua, additional, Molloy, Kelly R., additional, Chait, Brian T., additional, Goggins, Michael G., additional, Bhan, Irun, additional, Franses, Joseph W., additional, Yang, Xiaoyu, additional, Taplin, Mary-Ellen, additional, Wang, Xinan, additional, Christiani, David C., additional, Johnson, Bruce E., additional, Meyerson, Matthew, additional, Uppaluri, Ravindra, additional, Egloff, Ann Marie, additional, Denault, Elyssa N., additional, Spring, Laura M., additional, Wang, Tian-Li, additional, Shih, Ie-Ming, additional, Fairman, Jennifer E., additional, Jung, Euihye, additional, Arora, Kshitij S., additional, Yilmaz, Osman H., additional, Cohen, Sonia, additional, Sharova, Tatyana, additional, Chi, Gary, additional, Norden, Bryanna L., additional, Song, Yuhui, additional, Nieman, Linda T., additional, Pappas, Leontios, additional, Parikh, Aparna R., additional, Strickland, Matthew R., additional, Corcoran, Ryan B., additional, Mustelin, Tomas, additional, Eng, George, additional, Yilmaz, Omer H., additional, Matulonis, Ursula A., additional, Skates, Steven J., additional, Rueda, Bo R., additional, Drapkin, Ronny, additional, Klempner, Samuel J., additional, Deshpande, Vikram, additional, Ting, David T., additional, Rout, Michael P., additional, LaCava, John, additional, Walt, David R., additional, and Burns, Kathleen H., additional

Published
2023
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29. Cardiac tissue engineering

Author

Zhao, Yimu, primary, Eng, George, additional, Lee, Benjamin W., additional, Radisic, Milica, additional, and Vunjak-Novakovic, Gordana, additional

Published
2020
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30. List of contributors

Author

Abe, Masashi, primary, Ahlstrom, Jon D., additional, Albon, Julie, additional, Allickson, Julie, additional, Almeida-Porada, Graça, additional, Altschuler, Richard A., additional, Anderson, Daniel G., additional, Annabi, Nasim, additional, Arcidiacono, Judith, additional, Ashammakhi, Nureddin, additional, Atala, Anthony, additional, Athanasiou, Kyriacos A., additional, Awad, Hani A., additional, Badylak, Stephen F, additional, Balachander, Gowri, additional, Balkan, Wayne, additional, Bara, Jennifer J., additional, Barry, Michael P., additional, Baskaran, Harihara, additional, Bedell, Matthew L., additional, Belcher, Donald Andrew, additional, Berry, David B., additional, Bhat, Hina, additional, Bhat, Zuhaib F., additional, Bhatia, Sangeeta N., additional, Blackburn, Catherine Clare, additional, Blocki, Anna, additional, Blum, Kevin M., additional, Bochenek, Matthew A., additional, Bonassar, Lawrence J., additional, Bonventre, Joseph V., additional, Borrelli, Mimi R., additional, Bowles, Robby D., additional, Bradshaw, Amy D., additional, Bratt-Leal, Andres M., additional, Breuer, Christopher K., additional, Brewster, Luke, additional, Brey, Eric M., additional, Briquez, Priscilla S., additional, Buckwalter, J.A., additional, Burg, Karen J.L., additional, Burg, Timothy C., additional, Byambaa, Batzaya, additional, Chandra, Prafulla K., additional, Chen, Amanda X., additional, Chen, Fa-Ming, additional, Chen, Shaochen, additional, Chesterman, Julian, additional, Chhabra, Arnav, additional, Chong, Seow Khoon, additional, Clark, Richard A.F., additional, Cleary, Muriel A., additional, Coleman, M., additional, Cotsarelis, George, additional, Crystal, Ronald G., additional, Dagnelie, Gislin, additional, Darabi, Mohammad Ali, additional, Davidson, Jeffrey M., additional, Davidson, Joseph, additional, De Coppi, Paolo, additional, Delcassian, Derfogail, additional, de Vos, Paul, additional, Dominijanni, Anthony, additional, Donahue, Ryan, additional, Drain, Allison P., additional, Duvall, Craig L., additional, Dziki, Jenna L., additional, Elgalad, Abdelmotagaly, additional, Eng, George, additional, Falanga, Vincent, additional, Farhang, Niloofar, additional, Ferreira, Lino, additional, Fink, Donald W., additional, Fleming, Heather E., additional, Fong, Peter, additional, Frey, Mark R., additional, Gay, Denise, additional, Gerecht, Sharon, additional, Gersbach, Charles A., additional, Gibbs, D.M.R., additional, Gidwani, Simran, additional, González Morales, Shaimar R., additional, Goyal, Ritu, additional, Grant, Maria B., additional, Gray, Andrea, additional, Greisler, Howard P., additional, Grikscheit, Tracy C., additional, Grosh, Karl, additional, Guilak, Farshid, additional, Guo, Jason L., additional, Han, Yingli, additional, Hare, Joshua M., additional, Hassanbhai, Ammar Mansoor, additional, Hatzistergos, Konstantinos, additional, Hay, David C., additional, He, Xiao-Tao, additional, Henderson, Timothy, additional, Hickerson, Darren, additional, Hickerson, Darren H.M., additional, Hmadcha, Abdelkrim, additional, Hochman-Mendez, Camila, additional, Huang, Chao, additional, Hubbell, Jeffrey A., additional, Huelsmann, Joern, additional, Huh, Jun Tae, additional, Hunsberger, Joshua G., additional, Iannucci, Leanne E., additional, Inoue, Haruhisa, additional, Jackson, John, additional, Jiang, Yangzi, additional, Kalinichenko, Vladimir V., additional, Kanczler, J.M., additional, Karp, Jeffrey M., additional, Kasper, F. Kurtis, additional, Khademhosseini, Ali, additional, Kim, Ji Hyun, additional, Kimbrel, Erin A., additional, Klimanskaya, Irina, additional, Kohn, Joachim, additional, Kumar, Sunil, additional, Kyriakides, Themis R., additional, Lake, Spencer P., additional, Lam, Johnny, additional, Langer, Robert, additional, Lanza, Robert, additional, Leach, Timothy S., additional, Lee, Benjamin W., additional, Lee, Iris, additional, Lee, Sang Jin, additional, Li, David, additional, Li, Linheng, additional, Liu, Qian, additional, Ljubimov, Alexander V., additional, Lo, Chi, additional, Longaker, Michael T., additional, López-Beas, Javier, additional, Loring, Jeanne F., additional, Luo, Ying, additional, MacArthur, Ben D., additional, Madigan, Nicolas N., additional, Madry, Henning, additional, Magalhaes, Renata S., additional, Manley, Nancy Ruth, additional, Mansbridge, Jonathan, additional, Mao, Jeremy J., additional, Marshall, K.M., additional, Martin, J.A., additional, Martins-Green, M., additional, Maselli, Kathryn M., additional, Maxfield, Mark W., additional, McCracken, Kyle W., additional, Melville, James, additional, Mikos, Antonios G., additional, Millán, José del R., additional, Mirotsou, Maria, additional, Montoro, Daniel T., additional, Murphy, Matthew P., additional, Murphy, Sean V., additional, Musillo, Michael, additional, Muthukumaran, Padmalosini, additional, Navara, Adam M., additional, Nelson, Christopher E., additional, Niklason, Laura E., additional, Nowell, Craig Scott, additional, O’Keefe, Regis J., additional, O’Neill, Kathy E., additional, Oreffo, Richard O.C., additional, Ortiz, Ophir, additional, Palmer, Andre Francis, additional, Perdikis, Serafeim, additional, Petreaca, M., additional, Plikus, Maksim V., additional, Porada, Christopher D., additional, Post, Mark, additional, Prokop, Aleš, additional, Puri, Raj K., additional, Qian, Pengxu, additional, Radisic, Milica, additional, Raredon, Micha Sam Brickman, additional, Richie, Ellen Rothman, additional, Rouse, Paul, additional, Sadri-Ardekani, Hooman, additional, Saltzman, W. Mark, additional, Sampaio, Luiz C., additional, Schlieve, Christopher R., additional, Sha, Su-Hua, additional, Sharpe, Paul T., additional, Shastri, V. Prasad, additional, Shi, Yanhong, additional, Shupe, Thomas, additional, Sirabella, Dario, additional, Skardal, Aleksander, additional, Slack, J.M.W., additional, Sloan, Stephen R., additional, Soker, Shay, additional, Soria, Bernat, additional, Soria-Juan, Bárbara, additional, Stockdale, Frank E., additional, Stover, Josh, additional, Stransky, Thomas, additional, Stronks, H. Christiaan, additional, Stumpf, Patrick S., additional, Sung, Kyung Eun, additional, Swarr, Daniel, additional, Szkolnicka, Dagmara, additional, Takahashi, Jun, additional, Tang, D.K.O., additional, Tang, Winson, additional, Taylor, Doris A., additional, Teng, Yao, additional, Teoh, Swee Hin, additional, Smith, Anthony J., additional, Treffeisen, Elsa, additional, Tuan, Rocky S., additional, Vacanti, Joseph P., additional, van der Weele, Cor, additional, Vincent, Matthew, additional, Vunjak-Novakovic, Gordana, additional, Wahlberg, Lars U., additional, Wan, Derrick C., additional, Wang, Anne, additional, Wang, Dan, additional, Wang, Qiwei, additional, Wang, Yanling, additional, Wang, Yu-li, additional, Wang, Zhanwen, additional, Weaver, Valerie M., additional, Wells, J.A., additional, Welter, Jean F., additional, Wen, Feng, additional, Weston, Jake, additional, Whitsett, Jeffrey A., additional, Williams, James K., additional, Windebank, Anthony J., additional, Wong, Mark Eu-Kien, additional, Worgall, Stefan, additional, Wu, Iwen, additional, Wu, Rui-Xin, additional, Xie, Virginia Y., additional, Xing, Malcolm, additional, Yamada, Kenneth M., additional, Yamanaka, Shinya, additional, Yoo, James J., additional, Young, Simon, additional, Yu, Claire, additional, Yu, Hanry, additional, Yuan, Yifan, additional, Zacharias, William, additional, Zakko, Jason, additional, Zhang, Ai, additional, Zhang, Yuanyuan, additional, Zhang, Zheng, additional, Zhao, Chunfeng, additional, Zhao, Yimu, additional, and Zoloth, Laurie, additional

Published
2020
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31. Germline Determinants of Esophageal Adenocarcinoma

Author

Lee, Minyi, primary, Eng, George, additional, Handte-Reinecker, Anna, additional, Deshpande, Vikram S., additional, Yilmaz, Omer H., additional, Gala, Manish K., additional, Jeon, Alvin, additional, Stratulat, Eugeniu, additional, Zagani, Rachid, additional, Taylor, Martin S., additional, Rickelt, Steffen, additional, Kedrin, Dmitriy, additional, Batra, Anupam, additional, Hashmi, Ardeshir, additional, Nishioka, Norman S., additional, Hur, Chin, additional, Goyal, Lipika, additional, Bazerbachi, Fateh, additional, and Zukerberg, Lawrence, additional

Published
2023
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33. An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types

Author

Chen, Jung-Kuei, primary, Merrick, Karl A, additional, Kong, Yi Wen, additional, Izrael-Tomasevic, Anita, additional, Eng, George, additional, Handly, Erika D., additional, Patterson, Jesse C, additional, Suarez-Lopez, Lucia, additional, Hosios, Aaron M, additional, Dinh, Anh, additional, Kirkpatrick, Donald S, additional, Yu, Kebing, additional, Rose, Christopher Michael, additional, Hernandez, Jonathan M., additional, Hwangbo, Haeun, additional, Palmer, Adam C, additional, Vander Heiden, Matthew, additional, Yilmaz, Omer H, additional, and Yaffe, Michael B., additional

Published
2023
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34. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis

Author

Roper, Jatin, Tammela, Tuomas, Cetinbas, Naniye Malli, Akkad, Adam, Roghanian, Ali, Rickelt, Steffen, Almeqdadi, Mohammad, Wu, Katherine, Oberli, Matthias A, Sánchez-Rivera, Francisco J, Park, Yoona K, Liang, Xu, Eng, George, Taylor, Martin S, Azimi, Roxana, Kedrin, Dmitriy, Neupane, Rachit, Beyaz, Semir, Sicinska, Ewa T, Suarez, Yvelisse, Yoo, James, Chen, Lillian, Zukerberg, Lawrence, Katajisto, Pekka, Deshpande, Vikram, Bass, Adam J, Tsichlis, Philip N, Lees, Jacqueline, Langer, Robert, Hynes, Richard O, Chen, Jianzhu, Bhutkar, Arjun, Jacks, Tyler, and Yilmaz, Ömer H

Published
2017
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42. Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

Author

Massachusetts Institute of Technology. Department of Biology, Schenkel, Jason M, Herbst, Rebecca H, Canner, David, Li, Amy, Hillman, Michelle, Shanahan, Sean-Luc, Gibbons, Grace, Smith, Olivia C, Kim, Jonathan Y, Westcott, Peter, Hwang, William L, Freed-Pastor, William A, Eng, George, Cuoco, Michael S, Rogers, Patricia, Park, Jin K, Burger, Megan L, Rozenblatt-Rosen, Orit, Cong, Le, Pauken, Kristen E, Regev, Aviv, Jacks, Tyler, Massachusetts Institute of Technology. Department of Biology, Schenkel, Jason M, Herbst, Rebecca H, Canner, David, Li, Amy, Hillman, Michelle, Shanahan, Sean-Luc, Gibbons, Grace, Smith, Olivia C, Kim, Jonathan Y, Westcott, Peter, Hwang, William L, Freed-Pastor, William A, Eng, George, Cuoco, Michael S, Rogers, Patricia, Park, Jin K, Burger, Megan L, Rozenblatt-Rosen, Orit, Cong, Le, Pauken, Kristen E, Regev, Aviv, and Jacks, Tyler

Abstract

In tumors, a subset of CD8+ T cells expressing the transcription factor TCF-1 drives the response to immune checkpoint blockade. We examined the mechanisms that maintain these cells in an autochthonous model of lung adenocarcinoma. Longitudinal sampling and single-cell sequencing of tumor-antigen specific TCF-1+ CD8+ T cells revealed that while intratumoral TCF-1+ CD8+ T cells acquired dysfunctional features and decreased in number as tumors progressed, TCF-1+ CD8+ T cell frequency in the tumor draining LN (dLN) remained stable. Two discrete intratumoral TCF-1+ CD8+ T cell subsets developed over time-a proliferative SlamF6+ subset and a non-cycling SlamF6- subset. Blocking dLN egress decreased the frequency of intratumoral SlamF6+ TCF-1+ CD8+ T cells. Conventional type I dendritic cell (cDC1) in dLN decreased in number with tumor progression, and Flt3L+anti-CD40 treatment recovered SlamF6+ T cell frequencies and decreased tumor burden. Thus, cDC1s in tumor dLN maintain a reservoir of TCF-1+ CD8+ T cells and their decrease contributes to failed anti-tumor immunity.

Published
2022

43. The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Author

Massachusetts Institute of Technology. Department of Biology, Freed-Pastor, William A, Lambert, Laurens J, Ely, Zackery A, Pattada, Nimisha B, Bhutkar, Arjun, Eng, George, Mercer, Kim L, Garcia, Ana P, Lin, Lin, Rideout, William M, Hwang, William L, Schenkel, Jason M, Jaeger, Alex M, Bronson, Roderick T, Westcott, Peter MK, Hether, Tyler D, Divakar, Prajan, Reeves, Jason W, Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yilmaz, Omer H, Regev, Aviv, Jacks, Tyler, Massachusetts Institute of Technology. Department of Biology, Freed-Pastor, William A, Lambert, Laurens J, Ely, Zackery A, Pattada, Nimisha B, Bhutkar, Arjun, Eng, George, Mercer, Kim L, Garcia, Ana P, Lin, Lin, Rideout, William M, Hwang, William L, Schenkel, Jason M, Jaeger, Alex M, Bronson, Roderick T, Westcott, Peter MK, Hether, Tyler D, Divakar, Prajan, Reeves, Jason W, Deshpande, Vikram, Delorey, Toni, Phillips, Devan, Yilmaz, Omer H, Regev, Aviv, and Jacks, Tyler

Abstract

The CD155/TIGIT axis can be co-opted during immune evasion in chronic viral infections and cancer. Pancreatic adenocarcinoma (PDAC) is a highly lethal malignancy, and immune-based strategies to combat this disease have been largely unsuccessful to date. We corroborate prior reports that a substantial portion of PDAC harbors predicted high-affinity MHC class I-restricted neoepitopes and extend these findings to advanced/metastatic disease. Using multiple preclinical models of neoantigen-expressing PDAC, we demonstrate that intratumoral neoantigen-specific CD8+ T cells adopt multiple states of dysfunction, resembling those in tumor-infiltrating lymphocytes of PDAC patients. Mechanistically, genetic and/or pharmacologic modulation of the CD155/TIGIT axis was sufficient to promote immune evasion in autochthonous neoantigen-expressing PDAC. Finally, we demonstrate that the CD155/TIGIT axis is critical in maintaining immune evasion in PDAC and uncover a combination immunotherapy (TIGIT/PD-1 co-blockade plus CD40 agonism) that elicits profound anti-tumor responses in preclinical models, now poised for clinical evaluation.

Published
2022

47. Bowel Ischemia in COVID-19 Infection: One-Year Surgical Experience

Author

Hwabejire, John O., primary, Kaafarani, Haytham M. A., additional, Mashbari, Hassan, additional, Misdraji, Joseph, additional, Fagenholz, Peter J., additional, Gartland, Rajshri M., additional, Abraczinskas, Diane R., additional, Mehta, Raaj S., additional, Paranjape, Charudutt N., additional, Eng, George, additional, Saillant, Noelle N., additional, Parks, Jonathan, additional, Fawley, Jason A., additional, Lee, Jarone, additional, King, David R., additional, Mendoza, April E., additional, and Velmahos, George C., additional

Published
2021
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50. Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

Author

Schenkel, Jason M., primary, Herbst, Rebecca H., additional, Canner, David, additional, Li, Amy, additional, Hillman, Michelle, additional, Shanahan, Sean-Luc, additional, Gibbons, Grace, additional, Smith, Olivia C., additional, Kim, Jonathan Y., additional, Westcott, Peter, additional, Hwang, William L., additional, Freed-Pastor, William A., additional, Eng, George, additional, Cuoco, Michael S., additional, Rogers, Patricia, additional, Park, Jin K., additional, Burger, Megan L., additional, Rozenblatt-Rosen, Orit, additional, Cong, Le, additional, Pauken, Kristen E., additional, Regev, Aviv, additional, and Jacks, Tyler, additional

Published
2021
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