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495 results on '"Endris, Volker"'

1. BAP1 and PTEN mutations shape the immunological landscape of clear cell renal cell carcinoma and reveal the intertumoral heterogeneity of T cell suppression: a proof-of-concept study

Author

Friedhoff, Jana, Schneider, Felix, Jurcic, Christina, Endris, Volker, Kirchner, Martina, Sun, Angela, Bolnavu, Iulia, Pohl, Laura, Teroerde, Miriam, Kippenberger, Maximilian, Schwab, Constantin, Kaczorowski, Adam, Zschäbitz, Stefanie, Jäger, Dirk, Hohenfellner, Markus, Stenzinger, Albrecht, Duensing, Anette, and Duensing, Stefan

Published
2023
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3. A “Two-in-One Hit” Model of Shortcut Carcinogenesis in MLH1 Lynch Syndrome Carriers

Author

Wittemann, Jan-Niklas, Endris, Volker, Gerling, Leonie, Bertram, Veit, Neumuth, Marie Theres, Witt, Johannes, Graf, Sebastian, Kristiansen, Glen, Hommerding, Oliver, Haupt, Saskia, Zeilmann, Alexander, Heuveline, Vincent, Kazdal, Daniel, Gebert, Johannes, von Knebel Doeberitz, Magnus, Mecklin, Jukka-Pekka, Nattermann, Jacob, Ahadova, Aysel, Stenzinger, Albrecht, Seppälä, Toni, Hüneburg, Robert, Kloor, Matthias, and Bläker, Hendrik

Published
2023
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4. Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing

Author

Neumann, Olaf, Burn, Timothy C., Allgäuer, Michael, Ball, Markus, Kirchner, Martina, Albrecht, Thomas, Volckmar, Anna-Lena, Beck, Susanne, Endris, Volker, Goldschmid, Hannah, Lehmann, Ulrich, Seker-Cin, Huriye, Uhrig, Sebastian, Roessler, Stephanie, Budczies, Jan, Fröhling, Stefan, Longerich, Thomas, Wagner, Alex H., Vogel, Arndt, Schirmacher, Peter, Stenzinger, Albrecht, and Kazdal, Daniel

Published
2022
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5. Status quo of ALK testing in lung cancer: results of an EQA scheme based on in-situ hybridization, immunohistochemistry, and RNA/DNA sequencing

Author

Jurmeister, Philipp, Vollbrecht, Claudia, Jöhrens, Korinna, Aust, Daniela, Behnke, Anke, Stenzinger, Albrecht, Penzel, Roland, Endris, Volker, Schirmacher, Peter, Fisseler-Eckhoff, Annette, Neumann, Jens, Kirchner, Thomas, Büttner, Reinhard, Merkelbach-Bruse, Sabine, Kreipe, Hans, Jonigk, Danny, Jochum, Wolfram, Rodriguez, Regulo, Dietel, Manfred, Horst, David, Hummel, Michael, and von Laffert, Maximilian

Published
2021
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7. Harmonization and Standardization of Panel-Based Tumor Mutational Burden Measurement: Real-World Results and Recommendations of the Quality in Pathology Study

Author

Stenzinger, Albrecht, Endris, Volker, Budczies, Jan, Merkelbach-Bruse, Sabine, Kazdal, Daniel, Dietmaier, Wolfgang, Pfarr, Nicole, Siebolts, Udo, Hummel, Michael, Herold, Sylvia, Andreas, Johanna, Zoche, Martin, Tögel, Lars, Rempel, Eugen, Maas, Jörg, Merino, Diana, Stewart, Mark, Zaoui, Karim, Schlesner, Matthias, Glimm, Hanno, Fröhling, Stefan, Allen, Jeff, Horst, David, Baretton, Gustavo, Wickenhauser, Claudia, Tiemann, Markus, Evert, Matthias, Moch, Holger, Kirchner, Thomas, Büttner, Reinhard, Schirmacher, Peter, Jung, Andreas, Haller, Florian, Weichert, Wilko, and Dietel, Manfred

Published
2020
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8. Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

Author

Ronellenfitsch, Michael W., Harter, Patrick N., Kirchner, Martina, Heining, Christoph, Hutter, Barbara, Gieldon, Laura, Schittenhelm, Jens, Schuhmann, Martin U., Tatagiba, Marcos, Wagner, Gerhard Marquard Marlies, Endris, Volker, Brandts, Christian H., Mautner, Victor-Felix, Schrock, Evelin, Weicher, Wilko, Brors, Benedikt, von Deimling, Andreas, Mittelbronn, Michel, Steinbach, Joachim P., Reuss, David E., Glimm, Hanno, Stenzinger, Albrecht, and Frohling, Stefan

Subjects
Merck & Company Inc., Thermo Fisher Scientific Inc., Bayer AG, Bristol-Myers Squibb Co., Novartis AG, AstraZeneca PLC, Lapatinib, Cancer -- Care and treatment -- Genetic aspects, Methylation, Tyrosine -- Genetic aspects, Pharmaceutical industry, Genomics -- Genetic aspects, Neratinib, Scientific equipment industry -- Genetic aspects, Criminal investigation, Cancer research, Neurofibromatosis, Phenols (Class of compounds), Tumors, DNA, Scientists, Research funding, Health care industry
Abstract

BACKGROUND. Neurofibroma/schwannoma hybrid nerve sheath tumors (N/S HNSTs) are neoplasms associated with larger nerves that occur sporadically and in the context of schwannomatosis or neurofibromatosis type 2 or 1. Clinical management of N/S HNSTs is challenging, especially for large tumors, and established systemic treatments are lacking. METHODS. We used next-generation sequencing and array-based DNA methylation profiling to determine the clinically actionable genomic and epigenomic landscapes of N/S HNSTs. RESULTS. Whole-exome sequencing within a precision oncology program identified an activating mutation (p.Asp769Tyr) in the catalytic domain of the ERBB2 receptor tyrosine kinase in a patient with schwannomatosis-associated N/S HNST, and targeted treatment with the small-molecule ERBB inhibitor lapatinib led to prolonged clinical benefit and a lasting radiographic and metabolic response. Analysis of a multicenter validation cohort revealed recurrent ERBB2 mutations (p.Leu755Ser, p.Asp769Tyr, p.Val777Leu) in N/S HNSTs occurring in patients who met diagnostic criteria for sporadic schwannomatosis (3 of 7 patients), but not in N/S HNSTs arising in the context of neurofibromatosis (6 patients) or outside a tumor syndrome (1 patient), and showed that ERBB2-mutant N/S HNSTs cluster in a distinct subgroup of peripheral nerve sheath tumors based on genome-wide DNA methylation patterns. CONCLUSION. These findings uncover a key biological feature of N/S HNSTs that may have important diagnostic and therapeutic implications. FUNDING. This work was supported by grant H021 from DKFZ-HIPO, the University Cancer Center Frankfurt, and the Frankfurt Research Funding Clinician Scientist Program., Introduction Neurofibroma/schwannoma hybrid nerve sheath tumors (N/S HNSTs) are peripheral nerve sheath tumors that are recognized as a distinct entity by the 2016 update of the World Health Organization (WHO) [...]

Published
2020
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9. Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts

Author

Kazdal, Daniel, Endris, Volker, Allgäuer, Michael, Kriegsmann, Mark, Leichsenring, Jonas, Volckmar, Anna-Lena, Harms, Alexander, Kirchner, Martina, Kriegsmann, Katharina, Neumann, Olaf, Brandt, Regine, Talla, Suranand B., Rempel, Eugen, Ploeger, Carolin, von Winterfeld, Moritz, Christopoulos, Petros, Merino, Diana M., Stewart, Mark, Allen, Jeff, Bischoff, Helge, Meister, Michael, Muley, Thomas, Herth, Felix, Penzel, Roland, Warth, Arne, Winter, Hauke, Fröhling, Stefan, Peters, Solange, Swanton, Charles, Thomas, Michael, Schirmacher, Peter, Budczies, Jan, and Stenzinger, Albrecht

Published
2019
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13. PICCA study: panitumumab in combination with cisplatin/gemcitabine chemotherapy in KRAS wild-type patients with biliary cancer—a randomised biomarker-driven clinical phase II AIO study

Author

Vogel, Arndt, Kasper, Stefan, Bitzer, Michael, Block, Andreas, Sinn, Marianne, Schulze-Bergkamen, Henning, Moehler, Markus, Pfarr, Nicole, Endris, Volker, Goeppert, Benjamin, Merx, Kirsten, Schnoy, Elisabeth, Siveke, Jens T., Michl, Patrick, Waldschmidt, Dirk, Kuhlmann, Jan, Geissler, Michael, Kahl, Christoph, Evenkamp, Ralph, Schmidt, Torben, Kuhlmann, Alexander, Weichert, Wilko, and Kubicka, Stefan

Published
2018
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14. The BRCA2 mutation status shapes the immune phenotype of prostate cancer

Author

Jenzer, Maximilian, Keß, Peter, Nientiedt, Cathleen, Endris, Volker, Kippenberger, Maximilian, Leichsenring, Jonas, Stögbauer, Fabian, Haimes, Josh, Mishkin, Skyler, Kudlow, Brian, Kaczorowski, Adam, Zschäbitz, Stefanie, Volckmar, Anna-Lena, Sültmann, Holger, Jäger, Dirk, Duensing, Anette, Schirmacher, Peter, Hohenfellner, Markus, Grüllich, Carsten, Stenzinger, Albrecht, and Duensing, Stefan

Published
2019
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19. Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia

Author

Bochtler, Tilmann, Granzow, Martin, Stölzel, Friedrich, Kunz, Christina, Mohr, Brigitte, Kartal-Kaess, Mutlu, Hinderhofer, Katrin, Heilig, Christoph E., Kramer, Michael, Thiede, Christian, Endris, Volker, Kirchner, Martina, Stenzinger, Albrecht, Benner, Axel, Bornhäuser, Martin, Ehninger, Gerhard, Ho, Anthony D., Jauch, Anna, and Krämer, Alwin

Published
2017
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21. Supplementary Patient Data from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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22. Data from Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

Author

Horak, Peter, primary, Heining, Christoph, primary, Kreutzfeldt, Simon, primary, Hutter, Barbara, primary, Mock, Andreas, primary, Hüllein, Jennifer, primary, Fröhlich, Martina, primary, Uhrig, Sebastian, primary, Jahn, Arne, primary, Rump, Andreas, primary, Gieldon, Laura, primary, Möhrmann, Lino, primary, Hanf, Dorothea, primary, Teleanu, Veronica, primary, Heilig, Christoph E., primary, Lipka, Daniel B., primary, Allgäuer, Michael, primary, Ruhnke, Leo, primary, Laßmann, Andreas, primary, Endris, Volker, primary, Neumann, Olaf, primary, Penzel, Roland, primary, Beck, Katja, primary, Richter, Daniela, primary, Winter, Ulrike, primary, Wolf, Stephan, primary, Pfütze, Katrin, primary, Geörg, Christina, primary, Meißburger, Bettina, primary, Buchhalter, Ivo, primary, Augustin, Marinela, primary, Aulitzky, Walter E., primary, Hohenberger, Peter, primary, Kroiss, Matthias, primary, Schirmacher, Peter, primary, Schlenk, Richard F., primary, Keilholz, Ulrich, primary, Klauschen, Frederick, primary, Folprecht, Gunnar, primary, Bauer, Sebastian, primary, Siveke, Jens Thomas, primary, Brandts, Christian H., primary, Kindler, Thomas, primary, Boerries, Melanie, primary, Illert, Anna L., primary, von Bubnoff, Nikolas, primary, Jost, Philipp J., primary, Spiekermann, Karsten, primary, Bitzer, Michael, primary, Schulze-Osthoff, Klaus, primary, von Kalle, Christof, primary, Klink, Barbara, primary, Brors, Benedikt, primary, Stenzinger, Albrecht, primary, Schröck, Evelin, primary, Hübschmann, Daniel, primary, Weichert, Wilko, primary, Glimm, Hanno, primary, and Fröhling, Stefan, primary

Published
2023
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23. Supplementary Table S1 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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24. Supplementary Tables S1-S7 from Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

Author

Horak, Peter, primary, Heining, Christoph, primary, Kreutzfeldt, Simon, primary, Hutter, Barbara, primary, Mock, Andreas, primary, Hüllein, Jennifer, primary, Fröhlich, Martina, primary, Uhrig, Sebastian, primary, Jahn, Arne, primary, Rump, Andreas, primary, Gieldon, Laura, primary, Möhrmann, Lino, primary, Hanf, Dorothea, primary, Teleanu, Veronica, primary, Heilig, Christoph E., primary, Lipka, Daniel B., primary, Allgäuer, Michael, primary, Ruhnke, Leo, primary, Laßmann, Andreas, primary, Endris, Volker, primary, Neumann, Olaf, primary, Penzel, Roland, primary, Beck, Katja, primary, Richter, Daniela, primary, Winter, Ulrike, primary, Wolf, Stephan, primary, Pfütze, Katrin, primary, Geörg, Christina, primary, Meißburger, Bettina, primary, Buchhalter, Ivo, primary, Augustin, Marinela, primary, Aulitzky, Walter E., primary, Hohenberger, Peter, primary, Kroiss, Matthias, primary, Schirmacher, Peter, primary, Schlenk, Richard F., primary, Keilholz, Ulrich, primary, Klauschen, Frederick, primary, Folprecht, Gunnar, primary, Bauer, Sebastian, primary, Siveke, Jens Thomas, primary, Brandts, Christian H., primary, Kindler, Thomas, primary, Boerries, Melanie, primary, Illert, Anna L., primary, von Bubnoff, Nikolas, primary, Jost, Philipp J., primary, Spiekermann, Karsten, primary, Bitzer, Michael, primary, Schulze-Osthoff, Klaus, primary, von Kalle, Christof, primary, Klink, Barbara, primary, Brors, Benedikt, primary, Stenzinger, Albrecht, primary, Schröck, Evelin, primary, Hübschmann, Daniel, primary, Weichert, Wilko, primary, Glimm, Hanno, primary, and Fröhling, Stefan, primary

Published
2023
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25. Data from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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26. Supplementary Figure S2 from NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer

Author

Heining, Christoph, primary, Horak, Peter, primary, Uhrig, Sebastian, primary, Codo, Paula L., primary, Klink, Barbara, primary, Hutter, Barbara, primary, Fröhlich, Martina, primary, Bonekamp, David, primary, Richter, Daniela, primary, Steiger, Katja, primary, Penzel, Roland, primary, Endris, Volker, primary, Ehrenberg, Karl Roland, primary, Frank, Stephanie, primary, Kleinheinz, Kortine, primary, Toprak, Umut H., primary, Schlesner, Matthias, primary, Mandal, Ranadip, primary, Schulz, Lothar, primary, Lambertz, Helmut, primary, Fetscher, Sebastian, primary, Bitzer, Michael, primary, Malek, Nisar P., primary, Horger, Marius, primary, Giese, Nathalia A., primary, Strobel, Oliver, primary, Hackert, Thilo, primary, Springfeld, Christoph, primary, Feuerbach, Lars, primary, Bergmann, Frank, primary, Schröck, Evelin, primary, von Kalle, Christof, primary, Weichert, Wilko, primary, Scholl, Claudia, primary, Ball, Claudia R., primary, Stenzinger, Albrecht, primary, Brors, Benedikt, primary, Fröhling, Stefan, primary, and Glimm, Hanno, primary

Published
2023
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27. Supplementary Figures S1-S10 from Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

Author

Horak, Peter, primary, Heining, Christoph, primary, Kreutzfeldt, Simon, primary, Hutter, Barbara, primary, Mock, Andreas, primary, Hüllein, Jennifer, primary, Fröhlich, Martina, primary, Uhrig, Sebastian, primary, Jahn, Arne, primary, Rump, Andreas, primary, Gieldon, Laura, primary, Möhrmann, Lino, primary, Hanf, Dorothea, primary, Teleanu, Veronica, primary, Heilig, Christoph E., primary, Lipka, Daniel B., primary, Allgäuer, Michael, primary, Ruhnke, Leo, primary, Laßmann, Andreas, primary, Endris, Volker, primary, Neumann, Olaf, primary, Penzel, Roland, primary, Beck, Katja, primary, Richter, Daniela, primary, Winter, Ulrike, primary, Wolf, Stephan, primary, Pfütze, Katrin, primary, Geörg, Christina, primary, Meißburger, Bettina, primary, Buchhalter, Ivo, primary, Augustin, Marinela, primary, Aulitzky, Walter E., primary, Hohenberger, Peter, primary, Kroiss, Matthias, primary, Schirmacher, Peter, primary, Schlenk, Richard F., primary, Keilholz, Ulrich, primary, Klauschen, Frederick, primary, Folprecht, Gunnar, primary, Bauer, Sebastian, primary, Siveke, Jens Thomas, primary, Brandts, Christian H., primary, Kindler, Thomas, primary, Boerries, Melanie, primary, Illert, Anna L., primary, von Bubnoff, Nikolas, primary, Jost, Philipp J., primary, Spiekermann, Karsten, primary, Bitzer, Michael, primary, Schulze-Osthoff, Klaus, primary, von Kalle, Christof, primary, Klink, Barbara, primary, Brors, Benedikt, primary, Stenzinger, Albrecht, primary, Schröck, Evelin, primary, Hübschmann, Daniel, primary, Weichert, Wilko, primary, Glimm, Hanno, primary, and Fröhling, Stefan, primary

Published
2023
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28. Supplementary Methods from Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

Author

Horak, Peter, primary, Heining, Christoph, primary, Kreutzfeldt, Simon, primary, Hutter, Barbara, primary, Mock, Andreas, primary, Hüllein, Jennifer, primary, Fröhlich, Martina, primary, Uhrig, Sebastian, primary, Jahn, Arne, primary, Rump, Andreas, primary, Gieldon, Laura, primary, Möhrmann, Lino, primary, Hanf, Dorothea, primary, Teleanu, Veronica, primary, Heilig, Christoph E., primary, Lipka, Daniel B., primary, Allgäuer, Michael, primary, Ruhnke, Leo, primary, Laßmann, Andreas, primary, Endris, Volker, primary, Neumann, Olaf, primary, Penzel, Roland, primary, Beck, Katja, primary, Richter, Daniela, primary, Winter, Ulrike, primary, Wolf, Stephan, primary, Pfütze, Katrin, primary, Geörg, Christina, primary, Meißburger, Bettina, primary, Buchhalter, Ivo, primary, Augustin, Marinela, primary, Aulitzky, Walter E., primary, Hohenberger, Peter, primary, Kroiss, Matthias, primary, Schirmacher, Peter, primary, Schlenk, Richard F., primary, Keilholz, Ulrich, primary, Klauschen, Frederick, primary, Folprecht, Gunnar, primary, Bauer, Sebastian, primary, Siveke, Jens Thomas, primary, Brandts, Christian H., primary, Kindler, Thomas, primary, Boerries, Melanie, primary, Illert, Anna L., primary, von Bubnoff, Nikolas, primary, Jost, Philipp J., primary, Spiekermann, Karsten, primary, Bitzer, Michael, primary, Schulze-Osthoff, Klaus, primary, von Kalle, Christof, primary, Klink, Barbara, primary, Brors, Benedikt, primary, Stenzinger, Albrecht, primary, Schröck, Evelin, primary, Hübschmann, Daniel, primary, Weichert, Wilko, primary, Glimm, Hanno, primary, and Fröhling, Stefan, primary

Published
2023
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29. A “two-in-one hit” model of shortcut carcinogenesis in MLH1 Lynch syndrome carriers

Author

Ahadova, Aysel, primary, Stenzinger, Albrecht, additional, Seppälä, Toni, additional, Hüneburg, Robert, additional, Kloor, Matthias, additional, Bläker, Hendrik, additional, Wittemann, Jan-Niklas, additional, Endris, Volker, additional, Gerling, Leonie, additional, Bertram, Veit, additional, Neumuth, Marie Theres, additional, Witt, Johannes, additional, Graf, Sebastian, additional, Kristiansen, Glen, additional, Hommerding, Oliver, additional, Haupt, Saskia, additional, Zeilmann, Alexander, additional, Heuveline, Vincent, additional, Kazdal, Daniel, additional, Gebert, Johannes, additional, von Knebel Doeberitz, Magnus, additional, Mecklin, Jukka-Pekka, additional, and Nattermann, Jacob, additional

Published
2023
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30. Genome-wide analysis of pediatric-type follicular lymphoma reveals low genetic complexity and recurrent alterations of TNFRSF14 gene

Author

Schmidt, Janine, Gong, Shunyou, Marafioti, Teresa, Mankel, Barbara, Gonzalez-Farre, Blanca, Balagué, Olga, Mozos, Ana, Cabeçadas, José, van der Walt, Jon, Hoehn, Daniela, Rosenwald, Andreas, Ott, German, Dojcinov, Stefan, Egan, Caoimhe, Nadeu, Ferran, Ramis-Zaldívar, Joan Enric, Clot, Guillem, Bárcena, Carmen, Pérez-Alonso, Vanesa, Endris, Volker, Penzel, Roland, Lome-Maldonado, Carmen, Bonzheim, Irina, Fend, Falko, Campo, Elias, Jaffe, Elaine S., Salaverria, Itziar, and Quintanilla-Martinez, Leticia

Published
2016
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31. BRAF inhibition in hairy cell leukemia with low-dose vemurafenib

Author

Dietrich, Sascha, Pircher, Andreas, Endris, Volker, Peyrade, Frédéric, Wendtner, Clemens-Martin, Follows, George A., Hüllein, Jennifer, Jethwa, Alexander, Ellert, Elena, Walther, Tatjana, Liu, Xiyang, Dyer, Martin J.S., Elter, Thomas, Brummer, Tilman, Zeiser, Robert, Hermann, Michael, Herold, Michael, Weichert, Wilko, Dearden, Claire, Haferlach, Torsten, Seiffert, Martina, Hallek, Michael, von Kalle, Christof, Ho, Anthony D., Gaehler, Anita, Andrulis, Mindaugas, Steurer, Michael, and Zenz, Thorsten

Published
2016
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32. BAP1 and PTEN mutations shape the immunological landscape of clear cell renal cell carcinoma and reveal the intertumoral heterogeneity of T cell suppression: a proof-of-concept study

Author

Friedhoff, Jana, primary, Schneider, Felix, additional, Jurcic, Christina, additional, Endris, Volker, additional, Kirchner, Martina, additional, Sun, Angela, additional, Bolnavu, Iulia, additional, Pohl, Laura, additional, Teroerde, Miriam, additional, Kippenberger, Maximilian, additional, Schwab, Constantin, additional, Kaczorowski, Adam, additional, Zschäbitz, Stefanie, additional, Jäger, Dirk, additional, Hohenfellner, Markus, additional, Stenzinger, Albrecht, additional, Duensing, Anette, additional, and Duensing, Stefan, additional

Published
2022
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33. EGFR T790M mutation testing of non-small cell lung cancer tissue and blood samples artificially spiked with circulating cell-free tumor DNA: results of a round robin trial

Author

Fassunke, Jana, Ihle, Michaela Angelika, Lenze, Dido, Lehmann, Annika, Hummel, Michael, Vollbrecht, Claudia, Penzel, Roland, Volckmar, Anna-Lena, Stenzinger, Albrecht, Endris, Volker, Jung, Andreas, Lehmann, Ulrich, Zeugner, Silke, Baretton, Gustavo, Kreipe, Hans, Schirmacher, Peter, Kirchner, Thomas, Dietel, Manfred, Büttner, Reinhard, and Merkelbach-Bruse, Sabine

Published
2017
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35. NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial

Author

Endris, Volker, Stenzinger, Albrecht, Pfarr, Nicole, Penzel, Roland, Möbs, Markus, Lenze, Dido, Darb-Esfahani, Silvia, Hummel, Michael, Sabine-Merkelbach-Bruse, Jung, Andreas, Lehmann, Ulrich, Kreipe, Hans, Kirchner, Thomas, Büttner, Reinhard, Jochum, Wolfram, Höfler, Gerald, Dietel, Manfred, Weichert, Wilko, and Schirmacher, Peter

Published
2016
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37. Precision oncology based on omics data: The NCT Heidelberg experience

Author

Horak, Peter, Klink, Barbara, Heining, Christoph, Gröschel, Stefan, Hutter, Barbara, Fröhlich, Martina, Uhrig, Sebastian, Hübschmann, Daniel, Schlesner, Matthias, Eils, Roland, Richter, Daniela, Pfütze, Katrin, Geörg, Christina, Meißburger, Bettina, Wolf, Stephan, Schulz, Angela, Penzel, Roland, Herpel, Esther, Kirchner, Martina, Lier, Amelie, Endris, Volker, Singer, Stephan, Schirmacher, Peter, Weichert, Wilko, Stenzinger, Albrecht, Schlenk, Richard F., Schröck, Evelin, Brors, Benedikt, von Kalle, Christof, Glimm, Hanno, and Fröhling, Stefan

Published
2017
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40. Mutations in TP53 or DNA damage repair genes define poor prognostic subgroups in primary prostate cancer

Author

Nientiedt, Cathleen, primary, Budczies, Jan, additional, Endris, Volker, additional, Kirchner, Martina, additional, Schwab, Constantin, additional, Jurcic, Christina, additional, Behnisch, Rouven, additional, Hoveida, Shirin, additional, Lantwin, Philippa, additional, Kaczorowski, Adam, additional, Geisler, Christine, additional, Dieffenbacher, Svenja, additional, Falkenbach, Fabian, additional, Franke, Desiree, additional, Görtz, Magdalena, additional, Heller, Martina, additional, Himmelsbach, Ruth, additional, Pecqueux, Carine, additional, Rath, Mathias, additional, Reimold, Philipp, additional, Schütz, Viktoria, additional, Simunovic, Iva, additional, Walter, Elena, additional, Hofer, Luisa, additional, Gasch, Claudia, additional, Schönberg, Gita, additional, Pursche, Lars, additional, Hatiboglu, Gencay, additional, Nyarangi-Dix, Joanne, additional, Sültmann, Holger, additional, Zschäbitz, Stefanie, additional, Koerber, Stefan A., additional, Jäger, Dirk, additional, Debus, Jürgen, additional, Duensing, Anette, additional, Schirmacher, Peter, additional, Hohenfellner, Markus, additional, Stenzinger, Albrecht, additional, and Duensing, Stefan, additional

Published
2022
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41. Local ablative treatment with surgery and/or radiotherapy in single-site and oligometastatic carcinoma of unknown primary

Author

Pouyiourou, Maria, primary, Wohlfromm, Timothy, additional, Kraft, Bianca, additional, Hielscher, Thomas, additional, Stichel, Damian, additional, von Deimling, Andreas, additional, Delorme, Stefan, additional, Endris, Volker, additional, Neumann, Olaf, additional, Stenzinger, Albrecht, additional, Krämer, Alwin, additional, and Bochtler, Tilmann, additional

Published
2021
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42. Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine

Author

Horak, Peter, primary, Leichsenring, Jonas, additional, Goldschmid, Hannah, additional, Kreutzfeldt, Simon, additional, Kazdal, Daniel, additional, Teleanu, Veronica, additional, Endris, Volker, additional, Gieldon, Laura, additional, Allgäuer, Michael, additional, Volckmar, Anna‐Lena, additional, Dikow, Nicola, additional, Renner, Marcus, additional, Kirchner, Martina, additional, Penzel, Roland, additional, Ploeger, Carolin, additional, Brandt, Regine, additional, Seker‐Cin, Huriye, additional, Budczies, Jan, additional, Heilig, Christoph E., additional, Neumann, Olaf, additional, Schaaf, Christian P., additional, Schirmacher, Peter, additional, Fröhling, Stefan, additional, and Stenzinger, Albrecht, additional

Published
2021
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43. Validation of a Targeted Next-Generation Sequencing Panel for Tumor Mutation Burden Analysis

Author

Fenizia, Francesca, primary, Alborelli, Ilaria, additional, Costa, Jose Luis, additional, Vollbrecht, Claudia, additional, Bellosillo, Beatriz, additional, Dinjens, Winand, additional, Endris, Volker, additional, Heydt, Carina, additional, Leonards, Katharina, additional, Merkelback-Bruse, Sabine, additional, Pfarr, Nicole, additional, van Marion, Ronald, additional, Allen, Christopher, additional, Chaudhary, Ruchi, additional, Gottimukkala, Rajesh, additional, Hyland, Fiona, additional, Wong-Ho, Elaine, additional, Jermann, Philip, additional, Machado, Jose Carlos, additional, Hummel, Michael, additional, Stenzinger, Albrecht, additional, and Normanno, Nicola, additional

Published
2021
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44. Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers

Author

Horak, Peter, primary, Heining, Christoph, additional, Kreutzfeldt, Simon, additional, Hutter, Barbara, additional, Mock, Andreas, additional, Hüllein, Jennifer, additional, Fröhlich, Martina, additional, Uhrig, Sebastian, additional, Jahn, Arne, additional, Rump, Andreas, additional, Gieldon, Laura, additional, Möhrmann, Lino, additional, Hanf, Dorothea, additional, Teleanu, Veronica, additional, Heilig, Christoph E., additional, Lipka, Daniel B., additional, Allgäuer, Michael, additional, Ruhnke, Leo, additional, Laßmann, Andreas, additional, Endris, Volker, additional, Neumann, Olaf, additional, Penzel, Roland, additional, Beck, Katja, additional, Richter, Daniela, additional, Winter, Ulrike, additional, Wolf, Stephan, additional, Pfütze, Katrin, additional, Geörg, Christina, additional, Meißburger, Bettina, additional, Buchhalter, Ivo, additional, Augustin, Marinela, additional, Aulitzky, Walter E., additional, Hohenberger, Peter, additional, Kroiss, Matthias, additional, Schirmacher, Peter, additional, Schlenk, Richard F., additional, Keilholz, Ulrich, additional, Klauschen, Frederick, additional, Folprecht, Gunnar, additional, Bauer, Sebastian, additional, Siveke, Jens Thomas, additional, Brandts, Christian H., additional, Kindler, Thomas, additional, Boerries, Melanie, additional, Illert, Anna L., additional, von Bubnoff, Nikolas, additional, Jost, Philipp J., additional, Spiekermann, Karsten, additional, Bitzer, Michael, additional, Schulze-Osthoff, Klaus, additional, von Kalle, Christof, additional, Klink, Barbara, additional, Brors, Benedikt, additional, Stenzinger, Albrecht, additional, Schröck, Evelin, additional, Hübschmann, Daniel, additional, Weichert, Wilko, additional, Glimm, Hanno, additional, and Fröhling, Stefan, additional

Published
2021
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45. Distinct Mutational Profile of Lynch Syndrome Colorectal Cancers Diagnosed under Regular Colonoscopy Surveillance

Author

Ahadova, Aysel, primary, Pfuderer, Pauline Luise, additional, Ahtiainen, Maarit, additional, Ballhausen, Alexej, additional, Bohaumilitzky, Lena, additional, Kösegi, Svenja, additional, Müller, Nico, additional, Tang, Yee Lin, additional, Kosmalla, Kosima, additional, Witt, Johannes, additional, Endris, Volker, additional, Stenzinger, Albrecht, additional, von Knebel Doeberitz, Magnus, additional, Bläker, Hendrik, additional, Renkonen-Sinisalo, Laura, additional, Lepistö, Anna, additional, Böhm, Jan, additional, Mecklin, Jukka-Pekka, additional, Seppälä, Toni T., additional, and Kloor, Matthias, additional

Published
2021
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47. Earlier extracranial progression and shorter survival in ALK- rearranged lung cancer with positive liquid rebiopsies

Author

Christopoulos, Petros, primary, Dietz, Steffen, additional, Angeles, Arlou K., additional, Rheinheimer, Stephan, additional, Kazdal, Daniel, additional, Volckmar, Anna-Lena, additional, Janke, Florian, additional, Endris, Volker, additional, Meister, Michael, additional, Kriegsmann, Mark, additional, Zemojtel, Thomasz, additional, Reck, Martin, additional, Stenzinger, Albrecht, additional, Thomas, Michael, additional, and Sültmann, Holger, additional

Published
2021
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48. Assigning evidence to actionability: An introduction to variant interpretation in precision cancer medicine.

Author

Horak, Peter, Leichsenring, Jonas, Goldschmid, Hannah, Kreutzfeldt, Simon, Kazdal, Daniel, Teleanu, Veronica, Endris, Volker, Gieldon, Laura, Allgäuer, Michael, Volckmar, Anna‐Lena, Dikow, Nicola, Renner, Marcus, Kirchner, Martina, Penzel, Roland, Ploeger, Carolin, Brandt, Regine, Seker‐Cin, Huriye, Budczies, Jan, Heilig, Christoph E., and Neumann, Olaf

Published
2022
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49. Targeting rare and non-canonical driver variants in NSCLC – An uncharted clinical field

Author

Volckmar, Anna-Lena, primary, Christopoulos, Petros, additional, Kirchner, Martina, additional, Allgäuer, Michael, additional, Neumann, Olaf, additional, Budczies, Jan, additional, Rempel, Eugen, additional, Horak, Peter, additional, Glade, Julia, additional, Goldschmid, Hannah, additional, Seker-Cin, Huriye, additional, Brandt, Regine, additional, Kriegsmann, Mark, additional, Leichsenring, Jonas, additional, Winter, Hauke, additional, Faehling, Martin, additional, Fischer, Jürgen R., additional, Heußel, Claus Peter, additional, Herth, Felix, additional, Brummer, Tilman, additional, Fröhling, Stefan, additional, Schirmacher, Peter, additional, Thomas, Michael, additional, Endris, Volker, additional, Penzel, Roland, additional, Kazdal, Daniel, additional, Bochtler, Tilmann, additional, and Stenzinger, Albrecht, additional

Published
2021
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50. KRAS/GNAS‐testing by highly sensitive deep targeted next generation sequencing improves the endoscopic ultrasound‐guided workup of suspected mucinous neoplasms of the pancreas

Author

Schmitz, Daniel, primary, Kazdal, Daniel, additional, Allgäuer, Michael, additional, Trunk, Marcus, additional, Vornhusen, Sylke, additional, Nahm, Anna‐Maria, additional, Doll, Matthias, additional, Weingärtner, Simon, additional, Endris, Volker, additional, Penzel, Roland, additional, Kirchner, Martina, additional, Brandt, Regine, additional, Neumann, Olaf, additional, Sültmann, Holger, additional, Budczies, Jan, additional, Kienle, Peter, additional, Magdeburg, Richard, additional, Hetjens, Svetlana, additional, Schirmacher, Peter, additional, Bergmann, Frank, additional, Rudi, Jochen, additional, Stenzinger, Albrecht, additional, and Volckmar, Anna‐Lena, additional

Published
2021
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