Perales M, Valenzuela P., Barakat R., Alejo L.B., Cordero Rodríguez, Yaiza Adela, Peláez M., Lucía Mulas, Alejandro, Perales M, Valenzuela P., Barakat R., Alejo L.B., Cordero Rodríguez, Yaiza Adela, Peláez M., and Lucía Mulas, Alejandro
Referencias bibliográficas • Deputy N, Sharma A, Kim S, Hinkle S. Prevalence and characteristics associated with gestational weight gain adequacy. Obstet Gynecol. 2016;125:773–781. DOI: 10.1097/AOG.0000000000000739 • Goldstein RF, Abell SK, Ranasinha S, Misso M, Boyle JA, Black MH, et al. Association of gestational weight gain with maternal and infant outcomes: a systematic review and meta-analysis. JAMA. 2017;317:2207–2225. DOI: 10.1001/jama.2017.3635 • Perales M, Artal R, Lucia A. Exercise during pregnancy. JAMA. 2017;317:1113–1114. DOI: 10.1001/jama.2017.0593 • Tobias DK, Stuart JJ, Li S, Chavarro J, Rimm EB, Rich-Edwards J, et al. Association of history of gestational diabetes with long-term cardiovascular disease risk in a large prospective cohort of US women. JAMA Intern Med. 2017;177:1735–1742. DOI: 10.1001/jamainternmed.2017.2790 • Behrens I, Basit S, Lykke JA, Ranthe MF, Wohlfahrt J, Bundgaard H, et al. Association between hypertensive disorders of pregnancy and later risk of cardiomyopathy. JAMA. 2016;315:1026–1033. DOI: 10.1001/jama.2016.1869 • Palinski W. Effect of maternal cardiovascular conditions and risk factors on offspring cardiovascular disease. Circulation. 2014;129:2066–2077. DOI: 10.1161/CIRCULATIONAHA.113.001805 • Mottola MF, Davenport MH, Ruchat SM, Davies GA, Poitras V, Gray C, et al. 2019 Canadian guideline for physical activity throughout pregnancy. Br J Sports Med. 2018;52:1339–1346. DOI: 10.1136/bjsports-2018-100056 • Perales M, Valenzuela PL, Barakat R, Cordero Y, Peláez M, López C, et al. Gestational exercise and maternal and child health: effects until delivery and at post-natal follow-up. J Clin Med. 2020;9:379. DOI: 10.3390/jcm9020379 • Álvarez C, Ramírez-Campillo R, Ramírez-Vélez R, Izquierdo M. Effects and prevalence of nonresponders after 12 weeks of high-intensity interval or resistance training in women with insulin resistance: a randomized trial. J Appl Physiol. 2017;122:985–996. DOI: 10.1152/japplphysiol.01037.2016 • Álvarez, Pregnancy exercise can prevent excessive gestational weight gain (EGWG), gestational diabetes mellitus (GDM) and hypertension (GH), but inter-individual variability has not been explored. We aimed to analyze the prevalence--and potential sociodemographic and medical predictors of--non-responsiveness to gestational exercise, and the association of non-responsiveness with adverse pregnancy outcomes. Among 688 women who completed a supervised light-to-moderate intensity exercise program (three ~1-h sessions/week including aerobic, resistance, and pelvic floor muscle training) until near-term, those who showed EGWG, GDM or GH were considered 'non-responders'. A low prevalence of non-responders was observed for GDM (3.6%) and GH (3.4%), but not for EGWG (24.2%). Pre-pregnancy obesity was the strongest predictor of non-responsiveness for GH (odds ratio 8.40 [95% confidence interval 3.10-22.78] and EGWG (5.37 [2.78-10.39]), whereas having a highest education level attenuated the risk of being non-responder for GDM (0.10 [0.02-0.49]). Non-responsiveness for EGWG was associated with a higher risk of prolonged labor length, instrumental/cesarean delivery, and macrosomia, and of lower Apgar scores. No association with negative delivery outcomes was found for GDM/GH. In summary, women with pre-pregnancy obesity might require from additional interventions beyond light-to-moderate intensity gestational exercise (e.g., diet and/or higher exercise loads) to ensure cardiometabolic benefits, Depto. de Didáctica de las Lenguas, Artes y Educación Física, Fac. de Educación, TRUE, pub