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BACKGROUND Minimal change disease is a common cause of nephrotic syndrome in adults. There are few reported cases of vaccine-related podocytopathy with nephrotic-range proteinuria in the setting of a minimal change disease history. There have been rare reports of acute renal damage following vaccination to prevent COVID-19 and some cases of exacerbation of ongoing nephropathy. This report is a 33-year-old man with a 22-year history of nephrotic syndrome due to minimal change disease which exacerbated following a third dose of an mRNA SARS-CoV-2 vaccine for COVID-19. CASE REPORT We report a case of nephrotic syndrome after the third dose of the BNT162b2 mRNA COVID-19 vaccine. The patient presented with mild edema in the bilateral lower extremities and sacrum. Laboratory investigations confirmed nephrotic-range proteinuria and hypoalbuminemia. A kidney sonogram demonstrated mild renal parenchymal disease and a small non-obstructing right renal calculus. Renal biopsy revealed diffuse podocyte foot process effacement, punctuate IgG podocyte cytoplasmic staining, and minimal global glomerulosclerosis, consistent with a diagnosis of a diffuse podocytopathy with a minimal change disease phenotype. The patient was started on oral prednisone treatment, which led to remission of his symptoms and normalization of lab test results with normal BUN and Cr and resolution of proteinuria. Treatment was tapered off over the course of 28 weeks. CONCLUSIONS We presents a case of longstanding minimal change disease that showed exacerbation following a third dose of an mRNA vaccine for SARS-CoV-2. Although this may be a rare association, this case supports that patients with chronic glomerulonephritis need to be monitored.

A 70-year-old female patient developed acute interstitial nephritis (AIN) after treatment with non-steroidal anti-inflammatory drugs (NSAIDs), proton pump inhibitors (PPI), and Bromhexine. Renal biopsy confirmed the diagnosis, and the patient was treated with oral prednisone. Careful attention to timing of acute kidney injury (AKI) is crucial to diagnosing AIN.

This article covers the emergence of resistance economy in the Islamic Republic of Iran within the context of international sanctions, arguing that this policy ought to be understood beyond the historical context in which it emerged. The article captures the historical, political, and economic context in which the first comprehensive economic discourse of the post-revolutionary establishment emerges, and seeks to account for its scope, concerns, and objectives. Rather than another word for protectionism, import-substitution industrialisation, economic diversification of a rentier state or a mere response to sanctions, resistance economy as espoused by Ayatollah Khamenei, is a comprehensive economic policy discourse affecting all levels of state and society in the Islamic Republic of Iran. Rather than mitigating the impact of sanctions, resistance economy is an economic discourse that seeks to realise the revolutionary objective of economic independence, whilst transforming the economy of the Islamic Republic from a source of weakness to a source of strength in its pursuit of a new, more equitable international order. [ABSTRACT FROM AUTHOR]

One of the main cultural heritages associated with South-East Asian people’s way of life and economy is batik. Not only batik is a part of textile industries, playing an important role in industrial development, it also, like other wet textile processes, generates huge amounts of hazardous wastewater. Due to the presence of wax in the batik production process an efficient wastewater pre-treatment is necessary to appropriately prepare related effluent conditions for further conventional wastewater treatment. Accordingly, in this study, the application of a baffle separation tank to treat simulated batik effluent as an innovative wastewater pre-treatment method was investigated. Therefore, two sets of simulated batik wastewaters containing constant amounts of chemical components (wax, dye, and sodium silicate with different reactive dyes) were tested. In the next step, the removal efficiency of the discussed samples’ chemical components was calculated based on pre- and post-process analytical experiments during an hour-long pre-treatment run. Wax, sodium silicate, and reactive dye removal through the runs were in the ranges of 92–95, 32–42, and 2–5%, respectively. The results showed slight decreases in pH, COD, and conductivity values in the post-treated samples, the differences of which were within the ranges of 0.2–0.6, 52–107 mg/L and 9–27 μS/cm, respectively. Moreover, this technique presented an effective rate of reduction for effluent samples’ existing heavy metal concentration. [ABSTRACT FROM PUBLISHER]

Abstract: Nowadays, hydrogen is being utilized massively in industries as a clean fuel. Displacing of hydrogen due to unique chemical and physical properties has adversely affect on pipeline network, hence increases the potential risk of explosion. This study was carried out to determine the flame propagation of hydrogen/air and hydrogen–methane/air mixtures in pipeline. A 90° pipeline with L/D ratio of 40 was used. Pure hydrogen/air mixture with equivalence ratio, φ = 0.13, 0.17, 0.2, 0.24, 0.27 and 0.30 were used in this work. Different composition of hydrogen–methane–air mixtures were tested in this study i.e. 3%H2 + 97CH4, 4%H2 + 96CH4, 6%H2 + 94CH4 and 8%H2 + 92CH4. All mixtures were operated at ambient condition. The results show that bending is the critical part of pipeline and higher concentration of hydrogen can affect on maximum overpressure, flame speed and temperature rise of both pure hydrogen/air and methane-hydrogen/air mixtures. [Copyright &y& Elsevier]

BACKGROUND Minimal change disease is a common cause of nephrotic syndrome in adults. There are few reported cases of vaccine-related podocytopathy with nephrotic-range proteinuria in the setting of a minimal change disease history. There have been rare reports of acute renal damage following vaccination to prevent COVID-19 and some cases of exacerbation of ongoing nephropathy. This report is a 33-year-old man with a 22-year history of nephrotic syndrome due to minimal change disease which exacerbated following a third dose of an mRNA SARS-CoV-2 vaccine for COVID-19. CASE REPORT We report a case of nephrotic syndrome after the third dose of the BNT162b2 mRNA COVID-19 vaccine. The patient presented with mild edema in the bilateral lower extremities and sacrum. Laboratory investigations confirmed nephrotic-range proteinuria and hypoalbuminemia. A kidney sonogram demonstrated mild renal parenchymal disease and a small non-obstructing right renal calculus. Renal biopsy revealed diffuse podocyte foot process effacement, punctuate IgG podocyte cytoplasmic staining, and minimal global glomerulosclerosis, consistent with a diagnosis of a diffuse podocytopathy with a minimal change disease phenotype. The patient was started on oral prednisone treatment, which led to remission of his symptoms and normalization of lab test results with normal BUN and Cr and resolution of proteinuria. Treatment was tapered off over the course of 28 weeks. CONCLUSIONS We presents a case of longstanding minimal change disease that showed exacerbation following a third dose of an mRNA vaccine for SARS-CoV-2. Although this may be a rare association, this case supports that patients with chronic glomerulonephritis need to be monitored.