64 results on '"Elzayat S"'
Search Results
2. Radiological Analysis of the Facial Recess: Impact on Posterior Tympanotomy Difficulty During Pediatric Cochlear Implantation
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Elzayat, S, Mandour, M, Elfarargy, Hh, Lotfy, R, Soltan, I, Lotfy, A, Margani, V, Covelli, E, Monini, S, and Barbara, M
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posterior tympanotomy ,ct scan ,cochlear implant ,facial recess ,prediction ,Temporal Bone ,Cochlear Implantation ,Middle Ear Ventilation ,Facial Nerve ,Otorhinolaryngology ,Humans ,Surgery ,Child ,Retrospective Studies - Abstract
We analyzed several radiological features of the facial recess to correlate them with the intraoperative findings to highlight the most reliable predictors of posterior tympanotomy difficulty.Retrospective observational cohort study.Multicenter study at tertiary referral institutions.We included 184 pediatric patients who underwent cochlear implantation through the posterior tympanotomy approach. The correlation was attempted between 8 radiological features in the preoperative high-resolution computed tomography scan and intraoperative surgical difficulty.Posterior tympanotomy was straightforward in 136 (73.9%) patients. In contrast, it was challenging in 48 (26.1%) patients. The facial recess was aerated in 74.5% of patients. The mean (SD) posterior tympanotomy depth was 3.98 (0.867) mm. The mean (SD) chorda-facial angle was 27.67° (3.406°). The mean (SD) chorda-facial to stylomastoid length was 3.898 (0.6304) mm. The mean (SD) facial nerve second genu angle was 94.54° (6.631)°. Deep-unaerated facial recess wall was associated with the most difficulty. There was a statistically significant difference in the unchallenging and challenging posterior tympanotomy groups regarding the surgical duration (According to this analytic study, the chorda-facial angle, the facial recess aeration, and the chorda-facial to stylomastoid length were respectively the strongest preoperative radiological predictors of the surgical difficulty of posterior tympanotomy during cochlear implantation. Chorda-facial angle25.5° was associated with difficult posterior tympanotomy. The oblique parasagittal cut was essential for the radiological analysis of the facial recess.
- Published
- 2022
3. The role of preoperative computerized tomography in a safe posterior tympanotomy for cochlear implant surgery.
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Elzayat, S., Mahmoud, M., and Rasha, L.
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CONFERENCES & conventions , *COCHLEAR implants , *COMPUTED tomography , *MIDDLE ear ventilation - Abstract
Aposteriortympanostomy is a technique to proper access round window area to insert cochlear implant electrode into round window (RW ) membrane or through cochleostomy. We aimed in this research to classify with evaluation the anatomical relations in between facial nerve (FN)(vertical part), chorda tympani nerve, facial recess (FR)pneumatization inanaxialtemporal bone computerized tomography (CT) to be safe when posterior tympanotomy will be operated. A retrospective analytic study was established of the petrous bone CT scans .51 patients who prepared to cochlear implantation (CI)with classical mastoidectomy with posterior tympanotomy were included in this cohort study.Preoperative diagnostic CT of the petrous bones for all cases from January 2014 to November 2015.Correlations in anatomical variations were classified by several parameters including FN protrusion into the mastoid antrum, FR pneumatization, and the facial canal integrity.Anatomical relationships between the vertical segment and posterior tympanotomy were classified into three types: type 1, the FN has no protrusion with a regular facial canal withpneumatized FR; type 2,theFNis protruded into the mastoid antrum within canal within regular manner and/or poorly pneumatized FR;andtype3,theFNhassclerotic mastoid with noFRpneumatization. These results enable preoperative evaluation of the FN's status and difficulty while performing posterior tympanotomy, providing basic knowledge to prevent injury of the FN while performing a posterior tympanotomy. [ABSTRACT FROM AUTHOR]
- Published
- 2018
4. A systems approach to physician prescribed FES ambulation.
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Philips, C.A., Hendershot, D., Elzayat, S., Granek, H., and Granek, M.
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- 1989
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5. Endoscopic Fat Graft Myringoplasty Augmented With Hyaluronic Acid for Managing Large-Sized Eardrum Perforations; A Prospective Comparative Randomised Study.
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Mandour MF, Tomoum M, Elsheikh MN, El-Gharib A, Elzayat S, Barbara M, Margani V, Elfarargy HH, and Amer M
- Abstract
Objectives: We aimed to assess the outcomes of fat graft myringoplasty augmented with hyaluronic acid in closing large-sized eardrum perforations compared to the traditional underlay cartilage-perichondrium composite myringoplasty (CPCM)., Study Design: It was a prospective randomised comparative study., Settings: It was held in tertiary referral institutions between May 2020 and April 2022., Participants: We included 100 patients with a large-sized eardrum perforation (50%-75% of the eardrum surface area). Using the endoscopic transcanal approach, 50 patients were managed by fat graft myringoplasty augmented with hyaluronic acid, while CPCM managed the other 50 patients., Main Outcome Measures: We evaluated the closure rates 1, 6 months and 1 year after surgery. Also, we assessed the audiological performance of the patients with a successful closure before and 1 year after the operation., Results: Fat graft myringoplasty operation was statistically shorter than the CPCM. The closure rate 1 year after surgery was 92% in the first group and 86% in the second group, without a statistically significant difference between both groups. Successful air-bone gap closure to less than 10 dB occurred in 93.5% of group A and 81.4% of group B without a statistically significant difference. The mean postoperative air-bone gap was 5.3 ± 3.95 dB in the first group and 7.95 ± 5.17 dB in the second group, with a statistically significant difference., Conclusions: Fat graft myringoplasty augmented with hyaluronic acid was a reliable, safe, simple, and effective manoeuvre to close large-sized eardrum perforations compared to the conventional CPCM., (© 2024 John Wiley & Sons Ltd.)
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- 2024
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6. Does the Scutum of The External Auditory Canal Have a Role in The Stapedotomy Operation? A Radio-clinical Evaluation.
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Elzayat S, El-Shirbeny HA, Barbara M, Covelli E, Elsheikh MN, Salem MA, Ebeed AI, and Elfarargy HH
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- 2024
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7. Crooked Nose: Aesthetic and Functional Outcomes.
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Abdelhamid AS, Elzayat S, Elsherif HS, Amer MA, and Most SP
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Purpose: To highlight a detailed analysis of aesthetic and functional rhinoplasty outcomes utilizing the most recent highly validated Standardized Cosmesis Health Nasal Outcomes Survey (SCHNOS) for Middle Eastern crooked nose patients., Methods: A longitudinal cohort study scrutinizing preoperative rhinoplasty patients' satisfaction retrospectively and their postoperative outcomes prospectively. The patients fulfilled the Arabic SCHNOS during postoperative follow-up. Preoperative and postoperative responses were recorded and then reviewed and analyzed., Results: This study included 41 patients with a mean age of 27.8 years. Females represented 41.5% of patients. About 73% of patients had a history of trauma. 90% of patients underwent primary procedures for crooked nose correction. Twelve patients (29.3%) underwent surgery for functional reasons, and twenty-six (63.4%) had it for both aesthetic and functional issues. There was a statistically significant difference regarding changes in SCHNOS regarding nasal obstruction scores (SCHNOS-O) and nasal cosmesis scores (SCHNOS-C) ( p < 0.001). These findings coincided with a substantial reduction of all SCHNOS items postoperatively ( p < 0.001). There was no statistically significant relationship between changes in (SCHNOS-O) or (SCHNOS-C) pre-and postoperatively and either age, sex, history of trauma, or type of surgery. However, a statistically significant difference was detected when assessing the relationship between changes in SCHNOS-O and the reason for surgery., Conclusion: A thorough knowledge of three-dimensional pathology and time-associated changes is required to achieve optimal aesthetic and functional outcomes for crooked nose patients. The use of highly validated questionnaires like SCHNOS in clinical practice is highly encouraged to modify and trace surgical techniques to the most appropriate and successful ones for the patients., Competing Interests: Conflict of interestThere is no conflict of interest., (© Association of Otolaryngologists of India 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
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- 2024
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8. The role of using the submucosal conchoplasty technique for the management of concha bullosa in decreasing post-operative middle meatus synechia formation after functional endoscopic sinus surgery: a randomised controlled trial.
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Elgendy A, Khafagy Y, Elzayat S, and Ali Elouny AG
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- Humans, Female, Male, Adult, Middle Aged, Postoperative Complications prevention & control, Postoperative Complications etiology, Treatment Outcome, Young Adult, Sinusitis surgery, Turbinates surgery, Endoscopy methods, Endoscopy adverse effects
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Objective: The study aimed to compare the applicability of classic lateral lamellectomy versus submucosal conchoplasty techniques in managing concha bullosa during and after functional endoscopic sinus surgery., Methods: The study randomly divided 56 patients with bilateral concha bullosa into two groups. One group of patients underwent the submucosal conchoplasty technique and the other group underwent the lateral lamellectomy technique. The study compared the intra-operative findings, including the time required for each technique, the amount of intra-operative bleeding and the post-operative endoscopic outcome of the middle meatus and middle turbinate stability., Results: Submucosal conchoplasty was significantly more time-consuming than the lateral lamellectomy technique ( p = 0.001*). The difference in the intra-operative amount of bleeding was ( p = 0.086*). The lateral lamellectomy group showed a higher rate of synechia formation in the middle meatus ( p = 0.012*)., Conclusion: Submucosal conchoplasty is a valid technique for managing concha bullosa with better post-operative endoscopic outcomes.
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- 2024
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9. The association of bacterial biofilm and middle ear mucosa in patients with mucosal chronic suppurative otitis media.
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Nosair N, Elzayat S, Elsharaby R, Abdulghaffar IA, Elfarargy HH, and Sharaf NA
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- Humans, Female, Chronic Disease, Male, Adult, Middle Aged, Microscopy, Electron, Scanning, Adolescent, Child, Young Adult, Aged, Biofilms growth & development, Otitis Media, Suppurative microbiology, Ear, Middle microbiology, Mucous Membrane microbiology, Pseudomonas aeruginosa
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Objectives: To evaluate the bacterial biofilm's role in mucosal chronic suppurative otitis media (CSOM) utilizing scanning electron microscopy (SEM)., Methods: This study involved 123 participating patients with active and inactive mucosal CSOM who underwent tympanomastoid surgery. SEM was used to examine middle ear mucosa biopsies for the development of biofilms. Middle ear discharge or mucosal swabs from patients were cultured to detect any bacterial growth. The biofilm formation was correlated to the culture results., Results: The biofilm was present in 69.9 % of patients (59% of them were with active mucosal CSOM) and absent in 30.1% of the patients (70% of them were with inactive mucosal CSOM), being more statistically significant in active mucosal CSOM (p-value = 0.003). A correlation that was statistically significant was found between active mucosal CSOM and higher grades (3 and 4) of biofilms (p-value <0.05). The mucosal CSOM type and the results of the culture had a relationship that was statistically significant (p-value <0.001). 60% of patients had positive culture (70% of them were with active mucosal CSOM). There was a statistically significant relation between Pseudomonas aeruginosa bacterial growth and active mucosal CSOM (p-value = 0.004) as well as higher grades of biofilms in mucosal CSOM., Conclusion: Mucosal CSOM, especially the active type, is a biofilm-related disease. There is a significant relation between the state of mucosal CSOM (active or inactive) and culture results with predominance of Pseudomonas aeruginosa bacterial growth in active mucosal CSOM and in higher grades of biofilms in mucosal CSOM., (Copyright © 2024. Published by Elsevier España, S.L.U.)
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- 2024
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10. Endoscopic-Assisted Cochlear Implantation in Far Advanced Otosclerosis.
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Salem MA, Ghonim MR, Elzayat S, Elkahwagi M, Badr K, Essawy WM, and Fouad YA
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- Humans, Male, Female, Retrospective Studies, Middle Aged, Adult, Aged, Treatment Outcome, Otosclerosis surgery, Cochlear Implantation methods, Endoscopy methods
- Abstract
Objectives: To evaluate the effectiveness of cochlear implantation (CI) in case of far advanced otosclerosis and to evaluate the value of using intraoperative otoendoscopy to facilitate the identification of the round window membrane and the scala tympani without the need to remove the posterior canal wall or to perform a subtotal petrosectomy., Study Design: Retrospective case-series study., Setting: Tertiary academic CI center., Patients and Methods: This study was conducted on patients with far advanced otosclerosis who underwent endoscopic-assisted CI between January 2010 and June 2020 at the same CI center. The minimum follow-up period was 2 years after surgery., Results: Fourteen patients were included in the study. Ten patients had undergone a previous stapedotomy. Electrode insertion in the scala tympani was successfully accomplished in all cases included in the study. There was a statistically significant improvement in pure-tone average and speech discrimination scores in all cases of the study group (p < 0.0001). There were no statistically significant differences in postoperative pure-tone average or speech discrimination scores between cases with and without cochlear ossification or between cases with and without a previous stapedotomy (p > 0.05)., Conclusion: Endoscopic-assisted CI is an effective option for hearing restoration in patients with far advanced otosclerosis. Otoendoscopy can facilitate visualization and access to the scala tympani without the need to remove the posterior canal wall or to perform a subtotal petrosectomy., Competing Interests: The authors disclose no conflicts of interest., (Copyright © 2024, Otology & Neurotology, Inc.)
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- 2024
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11. The Efficacy of Budesonide as Intrapolyp Injection Agent in the Management of Type 2 CRSwNP.
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Elzayat S, Lasheen H, Gehad I, El-Deeb ME, Soltan I, Aouf MM, and Elgendy A
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- Humans, Budesonide, Chronic Disease, Prednisolone, Prospective Studies, Steroids adverse effects, Nasal Polyps complications, Nasal Polyps drug therapy, Rhinitis complications, Rhinitis drug therapy, Rhinitis chemically induced
- Abstract
Objectives: To assess the efficacy and safety of budesonide as an intrapolyp injection in chronic rhinosinusitis with nasal polyps (CRSwNP) in comparison to control and systemic steroids., Method: In a prospective double-blinded controlled randomized clinical trial, 150 patients with CRSwNP were divided into 3 groups in a ratio 1:1:1 where group (A) was given oral prednisolone 1 mg/kg tapered daily for 2 weeks, group (B) was given budesonide intrapolyp injection weekly for 5 consecutive weeks, and group (C) was given intrapolyp injection with saline as the control group. Patients were assessed upon Sinonasal Outcome Test (SNOT-22) score, Total Nasal Polyp score (TNPS), Serum IgE, absolute eosinophilic count, and morning cortisol level before treatment, 1 week and 6 months after completing their treatment protocol., Results: SNOT 22 score improved significantly in all groups compared to those at baseline. Reduction in the oral and injection groups was much greater than the control group (P
2 < 0.001), (P3 < 0.001), and the same trend concerning TNPS score (P2 < 0.001), (P3 < 0.001) but with no significant change in the control group., Conclusion: Intrapolyp steroid injection is considered a safe and effective method in nasal polyposis with limited side effects in comparison to systemic steroids. Using Budesonide as an agent for intrapolyp injection appears to be promising. It's advisable in patients with multiple relapses or high-risk patients to avoid repeated courses of oral steroids., Level of Evidence: 2 Laryngoscope, 134:2085-2092, 2024., (© 2023 The American Laryngological, Rhinological and Otological Society, Inc.)- Published
- 2024
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12. The role of budesonide intrapolyp injection in the management of type 2 chronic rhinosinusitis with nasal polyps: a randomised clinical trial.
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Elzayat S, Elgendy A, Lasheen H, El-Deeb ME, Aouf MM, and Gehad I
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- Humans, Budesonide adverse effects, Steroids therapeutic use, Prednisolone therapeutic use, Chronic Disease, Treatment Outcome, Nasal Polyps complications, Nasal Polyps drug therapy, Rhinosinusitis, Sinusitis complications, Sinusitis drug therapy, Rhinitis complications, Rhinitis drug therapy
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Problem: To assess the efficacy of budesonide intrapolyp injection in chronic rhinosinusitis with nasal polyps., Method: Ninety patients were divided into three groups; group A was given oral prednisolone, group B was given budesonide intrapolyp injection weekly for five consecutive weeks and group C was given budesonide as nasal irrigation for one month. Patients were assessed using Sino-Nasal Outcome Test 22 score, total nasal polyp score, serum immunoglobulin E, absolute eosinophilic count, and morning cortisol level before treatment, one week and three months after completing their treatment., Results: Total nasal polyp score decreased significantly in all groups compared to those at baseline. Reduction in the oral and injection groups was greater than the wash group ( p 2 = 0.004), ( p 3 < 0.001), and the same trend concerning Sino-Nasal Outcome Test 22 score ( p 2 < 0.001), ( p 3 < 0.001)., Conclusion: Budesonide is an effective agent used in intrapolyp injection with no documented systemic or visual side effects that has comparable results with oral steroids.
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- 2024
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13. Radioclinical Assessment of Posterior Tympanotomy Difficulties during Ordinary Cochlear Implantation: A Prospective Case-Series Study.
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Barbara M, Margani V, Covelli E, Romano A, Bozzao A, Lotfy R, Mandour M, Swaid A, Soltan I, Elzayat S, and Elfarargy HH
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- Humans, Prospective Studies, Middle Ear Ventilation, Mastoidectomy, Face, Cochlear Implantation, Cochlear Implants
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Objectives: This study proposes a preoperative radiologic scoring system for predicting posterior tympanotomy (PT) and mastoidectomy-associated difficulties during cochlear implantation (CI)., Study Design: It was a prospective case-series study., Settings: The included CI surgeries were performed at tertiary referral institutions from October 2022 to April 2023., Subjects: We included 73 CI candidates performed via the PT approach., Intervention: The proposed radiologic score, composed of 13 items, was fulfilled and evaluated before each CI surgery., Main Outcome Measure: We correlated this score with the intraoperative difficulty and surgical duration., Results: The operation was straightforward in 42 patients with a score of 3.87 ± 1.72 and challenging in 31 patients with a score of 10.66 ± 1.73. The radiologic score was strongly correlated with the surgical difficulty and duration (p < 0.0001)., Conclusions: Our proposed radiologic score was a valid, reliable, and precise tool to predict intraoperative difficulty during cochlear implantation. Chorda-facial angle was the strongest predictor, significantly affecting the difficulty, surgical duration, and preoperative radiologic score. A score equal to or more than 7.5 was expected to be associated with surgical difficulty., Competing Interests: Conflicts of interest: The authors of this manuscript declare no conflict of interest., (Copyright © 2024, Otology & Neurotology, Inc.)
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- 2024
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14. The Prevalence and Association of Biofilms With Otitis Media With Effusion: A Systematic Review and Meta-Analysis.
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Elzayat S, El-Deeb ME, El-Shirbeny HA, El-Shirbiny H, Abdel-Maboud M, and Nasr K
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- Humans, Adenoidectomy, Middle Ear Ventilation, Prevalence, Biofilms, Otitis Media epidemiology, Otitis Media microbiology, Otitis Media with Effusion epidemiology, Otitis Media with Effusion microbiology
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Purpose: We aimed to identify the role of bacterial biofilms in the chronicity of otitis media with effusion and its resistance to antibiotics. We illustrated this role by reviewing, analyzing, and correlating the findings with the results of the included studies to reach clear evidence., Methods: A comprehensive search of electronic databases (Scopus, PubMed, Web of Science, Cochrane, and GHL databases) was performed for all studies using the following strategy till April 2021 with the search terms: Biofilm and Middle ear effusion. We found 935 references, 421 were duplicates, and 514 were needed for further screening, and it was as follows: PubMed 215, Scopus 18, Cochrane 130, Web of Science 136, and GHL 15., Results: The pooled prevalence of culture-positive effusions was estimated to be 40% (95% CI [28%, 53%]) of the total OME population. Overall, the prevalence of PCR-positive effusions was estimated to be 97% (95% CI [95%, 99%]) of the total OME population. The pooled prevalence of EM-positive effusions was estimated to be 82% (95% CI [69%, 95%]) of the total OME population., Conclusion: The data presented in this study coincide with the significant role of bacterial biofilms in the pathogenesis of chronic otitis media with effusion. The involvement of bacterial biofilm as a component of the OME pathogenic process can help us to explain why antimicrobial therapy is not always effective in the eradication of the disease process and, also explain the recurrence of middle ear effusion after treatment with tympanostomy tubes either with or without adenoidectomy., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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15. Localization of the Vertical Part of the Facial Nerve in the High-Resolution Computed Tomography During Pediatric Cochlear Implantation.
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Mandour M, Amer M, Elzayat S, Covelli E, Barbara M, Lotfy R, H Elfarargy H, and Osama Tomoum M
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- Humans, Child, Facial Nerve diagnostic imaging, Facial Nerve surgery, Temporal Bone diagnostic imaging, Temporal Bone surgery, Tomography, X-Ray Computed methods, Round Window, Ear diagnostic imaging, Round Window, Ear surgery, Cochlear Implantation methods
- Abstract
Background: This study proposed a classification of the vertical portion of the facial nerve (VPFN) location, incorporating the previous classifications regarding the posterior-to-anterior and medial-to-lateral dimensions. We also evaluated the implication of this proposed classification on the round window visibility during pediatric cochlear implantation (CI)., Methods: It was a retrospective multicenter observational cohort study. This study included 334 cases that underwent CI between 2015 and 2022 at multiple referral institutes. Two physicians evaluated the preoperative computed tomography images of 334 patients and determined the radiological type of the VPFN. These types were matched with intraoperative round window accessibility., Results: The Spearman's correlation coefficient showed a strong correlation between the proposed VPFN type and the intraoperative round window visibility, as the P-value was <.001., Conclusion: This classification could provide the surgeon preoperatively with the precise location of the VPFN in the lateral-to-medial and posterior-to-anterior dimensions. Furthermore, this location classification of the VPFN was significantly correlated with intraoperative round window accessibility, with an accuracy of 90.42%. Therefore, types C and D were expected to have difficult accessibility into the round window, and more surgical interventions were needed to modify the posterior tympanotomy or use other approaches.
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- 2024
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16. Surgical Management of Bilateral Abductor Paralysis: Diode Laser Versus Coblation; A Prospective Study.
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El-Sobki A, Elzayat S, El-Deeb ME, Ibrahim RAE, Gehad I, Negm A, Alsobky MEI, and Elgendy A
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Objectives: We aimed to compare the results of both diode laser and coblation in the treatment of bilateral vocal fold immobility (BVFI)., Materials and Methods: This prospective clinical study was performed on 80 non-tracheostomised patients with bilateral vocal fold paralysis divided into two groups; Group A: diode laser, Group B: coblation. Medical Research Council "mMRC" Dyspnea scale, maximal phonatory time (MPT), Voice handicap index (VHI), and functional outcome swallowing scale (FOSS) were assessed preoperatively and postoperatively. Also, the VAS pain scale and operative time of both groups are recorded., Results: Within each group, there was a statistically significant decrease in the mMRC dyspnea scale and maximum phonation time and a significant increase in VHI (P < 0.001). There was a statistically significant difference between the studied groups postoperative and regarding the percent change of the MPT ( more decrease in the coblation group). Concerning the operative time and the VAS pain score, there was a statistically significant difference between the studied groups regarding operating time and the VAS pain scale (significantly lower in the coblation group) (P < 0.001)., Conclusion: Both Coblation and diode laser are effective tools in the treatment of BVFI with similar minimal voice quality affection. The maximum phonation time decreased more in the coblation group, while the voice handicap index did not significantly differ between both groups. However, Coblation may be superior to diode laser in terms of less operative pain and shorter intraoperative time. Coblation may be more favorable for patients at risk of prolonged general anesthesia duration., Competing Interests: Declaration of Competing Interest There is no conflict of interest., (Copyright © 2023 The Voice Foundation. Published by Elsevier Inc. All rights reserved.)
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- 2023
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17. Assessment of the ability of the radiological incudo-stapedial angle to predict the stapedotomy technique type: a prospective case-series study.
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Barbara M, Elzayat S, El-Shirbeny HA, Salem MA, Ebeed AI, Covelli E, Volpini L, Margani V, and Elfarargy HH
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- Humans, Prospective Studies, Stapes diagnostic imaging, Incus surgery, Stapes Surgery methods, Ossicular Prosthesis, Otosclerosis diagnostic imaging, Otosclerosis surgery
- Abstract
Purpose: This study aimed to propose a radiological classification of the incudo-stapedial angle by preoperative high-resolution computed tomography (HRCT) images and to highlight its importance for predicting the use of reversal-steps stapedotomy (RSS) rather than the traditional non-reversal technique., Methods: We included 83 candidates for stapedotomy operation. Two physicians measured the radiological incudo-stapedial joint angle in the preoperative HRCT. According to this measurement, the radiological incudo-stapedial joint was classified into three types: obtuse, right, and acute. In addition, this radiological classification was correlated with the intraoperative use of the stapedotomy technique, either reversal or non-reversal., Results: The RSS technique was used in forty-two (97.7%) cases with an obtuse angle and twenty-six (89.7%) with a right angle. At the same time, the traditional non-reversal technique was used in all patients with an acute angle. The three groups differed significantly regarding the method used for stapedotomy (P value < 0.001). Moreover, Spearman's correlation coefficient revealed a significant correlation between the used technique and the radiological type of the incudo-stapedial angle (P value < 0.001)., Conclusions: This prospective study proposed a preoperative radiological classification of the incudo-stapedial angle. This classification was significantly correlated with the type of stapedotomy technique. The RSS technique was feasible in most cases with an obtuse and right radiological incudo-stapedial angle. In contrast, the non-reversal method was used in all patients with an acute radiological incudo-stapedial angle. This radiological classification could predict the choice for the stapedotomy technique with an accuracy of 95.18%, a sensitivity of 73.33%, and a specificity of 100%., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2023
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18. Evaluation of swallowing in children with higher grades glottic web.
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El-Sobki A, Ae Ibrahim R, Elzayat S, El-Deeb ME, Ashraf B, Hashish MI, Alsobky MEI, and Salamah A
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- Humans, Child, Deglutition, Glottis surgery, Water, Deglutition Disorders diagnosis, Deglutition Disorders etiology, Airway Obstruction
- Abstract
Purpose: to evaluate the swallowing function in children with higher grades of glottic web and to detect the impact of surgical division of the glottic web on the swallowing parameters. We also performed a voice analysis as a secondary objective in this study., Methods: This prospective case series study included 12 children with higher grades of the glottic web; grades 3 and 4. Evaluation of the swallowing function was done by clinical swallowing evaluation including symptoms and signs of swallowing dysfunction during feeding, such as vomiting, coughing, choking, or cyanosis, and bedside swallowing assessment using the 3-oz water swallow test. Instrumental evaluation of swallowing function was performed using flexible endoscopic evaluation of swallowing (FEES). The evaluation was performed both preoperatively and postoperatively., Results: The number of children suffering from swallowing difficulties significantly increased during the postoperative evaluation where 6 (50%) children demonstrated choking during feeding after the surgical division of the web in comparison to only 3 (25%) preoperatively. Also, coughing and choking during the 3-oz water swallow test significantly increased following the division of the web with P < 0.001., Conclusion: Swallowing assessment is mandatory as children with higher grades of the glottic web, requiring reconstructive surgeries, are at risk of swallowing deficit which can be aggravated postoperatively. With improvement in the airway and surgery-specific outcomes, swallowing function is an important secondary outcome that has a significant impact on the lives of these kids and their families., (© 2023. The Author(s).)
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- 2023
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19. Invasive fungal rhinosinusitis associated with COVID-19: Course changes and prognosis predictors.
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Barbara M, Elzayat S, Lotfy A, Sabino L, Bandiera G, Elsherif HS, Youssef M, Fouad A, Nasr K, Volpini L, and Elfarargy HH
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Background: This study aimed to analyze the behavior of acute invasive fungal rhinosinusitis (AIFRS) associated with COVID-19 infection as there has been an increase in the rate of AIFRS cases in the last two years, and many reports connected this rising with the COVID-19 infection. We studied most factors that may impact the prognosis as a trial to find the most affecting factors to improve the outcomes., Methods: It was a retrospective observational study that included cases from four tertiary referral institutions between November 2020 to February 2022. We included sixty-six patients who suffered from AIFRS associated with confirmed COVID-19. We observed the prognosis of all included patients with a six-month follow-up. We correlated the prognosis with many factors, such as demographic data, medical conditions, blood investigations, the features of fungal infections, and management., Results: Forty-two patients (64%) survived after the AIFRS associated with COVID-19, and twenty-two patients (36%) died. High doses of corticosteroids with prolonged use were the main factors that affected the behavior of the AIFRS associated with COVID-19. HbA1c was a good predictor of the prognosis; a level less than 9.35% may indicate survival with 87.5% sensitivity., Conclusions: According to this multi-center study, the mortality of the AIFRS associated with COVID-19 was high. The behavior was affected by glycemic control, the type of fungal species, and the type of antifungal therapy. Early surgical debridement, a combination of Amphotericin B with Voriconazole, and anticoagulants helped improve the prognosis., (Copyright © 2022. Published by Elsevier España, S.L.U.)
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- 2023
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20. The novel traction-suturing technique in correction of caudal end deviation of the nasal septum.
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Sabino L, Cavalcanti L, Marcaccio C, Elzayat S, Procaccini A, Elfarargy HH, and Barbara M
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- Humans, Treatment Outcome, Traction adverse effects, Quality of Life, Nasal Septum surgery, Suture Techniques, Nasal Obstruction etiology, Nasal Obstruction surgery, Rhinoplasty methods, Nose Deformities, Acquired surgery, Nose Deformities, Acquired complications
- Abstract
Background: Caudal end correction is one of the main challenges during septoplasty that needs extra steps and skills. This complex area affects the shape of the nose. Moreover, the caudal end represents the medial boundary of the internal nasal valve. Thus, any deviation may disturb this critical area causing nasal obstruction. This study aimed to evaluate the novel traction-suture technique to correct septal caudal end deviation and its postoperative impact., Study Design: This prospective case-series study., Settings: It was held in a tertiary referral university institute between January 2019 to February 2022., Methods: We included 95 cases who suffered from nasal obstruction and a cosmetic problem because of mild or moderate caudal end deviation. Under general anesthesia, the caudal end was corrected by the novel traction-suturing technique (TST). To evaluate the surgical outcomes and patients' related quality of life, we used two validated questionnaires; the Nasal Obstruction Symptom Evaluation and the Rhinoplasty Outcome Evaluation before the surgery and 1 year after the surgery., Results: NOSE and ROE questionnaires showed statistically significant improvements after the surgery (P value was < 0.001). Complications occurred in seven patients (7.3%), all of which were minor complications., Conclusions: Traction-suturing technique (TST) improved nasal breathing and patients' satisfaction with their nasal configuration. Traction-suturing is a simple short maneuver that junior doctors can easily learn without distinct complications or recurrence., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2023
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21. Lower Four Cranial Nerves in the Management of Glomus Jugulare: Anatomical Study.
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Fayed A, El-Deeb ME, Magnan J, Meller R, Deveze A, and Elzayat S
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Introduction The surgical management that achieves minimal morbidity and mortality for patients with glomus and non-glomus tumors involving the jugular foramen (JF) region requires a comprehensive understanding of the complex anatomy, anatomic variability, and pathological anatomy of this region. Objective The aim of this study is to propose a rational guideline to expose and preserve the lower cranial nerves (CNs) in the lateral approach of the JF. Methods The technique utilized is the gross and microdissection of 4 fixed cadaveric heads to revise the JF's surgical anatomy and high part of the carotid sheath compared with surgical cases to understand and preserve the integrity of lower CNs. The method involves radical mastoidectomy, microdissection of the JF, facial nerve, and high neck just below the carotid canal and the JF. The CNs IX, X, XI, and XII are microscopically dissected and kept in sight up to the JF. Results This study realized well the surgical and applied anatomy of the lower CNs with relation to the facial nerve and JF. Conclusions The JF anatomy is complicated, and the key to safely operate on it and preserving the lower CNs is to find the posterior belly of the digastric muscle, to skeletonize the facial nerve, to remove the mastoid tip preserving the stylomastoid foramen, to skeletonize the sigmoid sinus and posterior fossa dura not only anterior but also posteroinferior to reach and drill the jugular tubercle., Competing Interests: Conflict of interests The authors have no conflict of interests to declare., (Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
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- 2023
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22. The impact of adding platelet-rich plasma during fat graft myringoplasty for managing medium-sized tympanic membrane perforations: A prospective randomized case-control study.
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Mandour MF, Elsheikh MN, Amer M, Elzayat S, Barbara M, Covelli E, Elfarargy HH, and Tomoum M
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- Humans, Myringoplasty adverse effects, Case-Control Studies, Prospective Studies, Treatment Outcome, Adipose Tissue transplantation, Tympanic Membrane, Tympanic Membrane Perforation surgery, Tympanic Membrane Perforation etiology, Platelet-Rich Plasma
- Abstract
Purpose: This study aimed to evaluate the effect of adding platelet-rich plasma (PRP) during FGM to close medium-sized TM perforations., Methods: This prospective randomized case-control study was conducted from February 2017 to March 2022. We included 320 patients with a medium-sized TM perforation with inactive mucosal otitis media. Transcanal FGM managed all patients under general or local anesthesia according to the patient preference. According to PRP, patients were divided into two groups: the first with PRP (170 patients) and the other without PRP (150 patients). We evaluated the closure rate of both groups one month, six months, and one year after the surgery. Also, we assessed the audiological performance before and one year after the operation for the patients with a successful closure., Results: The closure rate was 87.6 % in the first group and 72.7 % in the second group, with a statistically significant difference between both groups as the P-value, was 0.001. Successful closure of the ABG to <10 dB occurred in 95.3 % of group A and 90.8 % of group B without a statistically significant difference between both groups (P-value = 0.163)., Conclusions: This prospective comparative study on a relatively large number of patients revealed that FGM effectively closed medium-sized TM perforations. It also significantly improved postoperative audiological performance in both groups. Adding PRP during the FGM enhanced the closure success and the healing process without recorded complications. We recommend using the PRP in the routine FGM for closing medium-sized TM perforations., Competing Interests: Declaration of competing interest There is no conflict of interest., (Copyright © 2022 Elsevier Inc. All rights reserved.)
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- 2023
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23. Arabic translation, cultural adaptation, and validation of the BDDQ-AS for rhinoplasty patients.
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Abdelhamid AS, Elzayat S, Amer MA, Elsherif HS, Lekakis G, and Most SP
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- Humans, Young Adult, Adult, Reproducibility of Results, Translations, Surveys and Questionnaires, Esthetics, Cross-Cultural Comparison, Rhinoplasty
- Abstract
Background: Body Dysmorphic Disorder (BDD) is a significant aspect that compromises patient satisfaction after rhinoplasty. BDDQ-AS (Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery) is a validated, simple, reliable patient-reported outcome measure. It is a screening tool to detect body dysmorphic disorder in rhinoplasty patients. This study aimed to translate, culturally adapt, and validate BDDQ-AS to Arabic as a novel tool for screening and detecting BDD in Arabic rhinoplasty individuals., Methods: BDDQ-AS was translated from English to Arabic following the international consensus guidelines. We tested the translation on ten Arabic-speaking rhinoplasty patients to ensure that the final version was understandable and acceptable. The proposed Arabic version was then completed by 112 patients whose average age was 28.79 ± 9.32 years. The screening is assumed positive if the patients expressed bother and preoccupation about their appearance (questions 1 and 2 "yes"), as well as a moderately disrupted everyday life (question 7 "yes" or questions 3, 4, 5, or 6 are equal to or greater than "3''). The internal consistency, test-retest reliability, and item-response theory (IRT) were used to evaluate psychometric validations., Results: The Arabic BDDQ had a high level of internal consistency, as measured by Cronbach's alpha 0.995. The A-BDDQ-AS was deemed reliable with an Intraclass Correlation Coefficient (ICC) of 0.989. A-BDDQ had good discrimination scores (above 2.0) with adequate difficulty parameters. The overall scale content validity average was 0.83, affirming that all items were relevant, clear, and straightforward., Conclusion: The Arabic version of the BDDQ-AS is reliable, culturally adapted, and psychometrically validated to be readily used and incorporated into clinical practice. It is a beneficial tool that can guide the screening of Arabic rhinoplasty patients suffering from body dysmorphic disorder and be utilized in further studies to optimize patient outcomes., (© 2023. The Author(s).)
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- 2023
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24. Validation of the radiological detection of the chorda-facial angle: impact on the round window accessibility during pediatric cochlear implantation.
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Elzayat S, Elfarargy HH, Lotfy R, Soltan I, Lasheen HN, Margani V, Covelli E, Barbara M, and Mandour M
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- Humans, Child, Retrospective Studies, Temporal Bone, Round Window, Ear diagnostic imaging, Round Window, Ear surgery, Chorda Tympani Nerve surgery, Cochlear Implantation methods, Cochlear Implants
- Abstract
Objectives: The facial recess, an essential landmark for the posterior tympanotomy approach, is limited by the facial nerve and the chorda tympani, with a complicated relationship. This study tried to find the most appropriate radiological method to evaluate the chorda-facial angle (CFA). We also checked the effect of this angle on the round window accessibility during cochlear implantation., Methods: It was a retrospective study that included cochlear implant surgeries of 237 pediatric patients, from September 2016 to April 2021. Two physicians evaluated the CFA in the para-sagittal cut of the preoperative HRCT. The round window accessibility was assessed in the unedited surgery videos., Results: The CFA ranged from 21° to 35° with a mean of 27.14 ± 3.5°. It was detected in all cases with a high agreement between the two CT reviewers' measurements. The CFA differed significantly between the accessible group and the group with difficult accessibility (p value < 0.001). Spearman's correlation coefficient revealed a strong correlation between the CFA and the intraoperative round accessibility. 25.5° was the best cutoff point; below this angle, difficult accessibility into the RW was expected, with high sensitivity, specificity, and accuracy CONCLUSIONS: Our study on a relatively large number of cases provided a precise, valid, reliable, and applicable method to evaluate the CFA in the HRCT scan. We found a significant-close relation between the CFA and the round window accessibility; the difficulty increased with a need for posterior tympanotomy modification when the angle decreased., Key Points: • Radiological detection of the chorda-facial angle was always problematic, without a previous straightforward method in the literature. • We used the para-sagittal cut of the high-resolution CT scans to evaluate the CFA. This cut was beneficial to seeing the chorda tympani nerve in every examined case. There was a high agreement between the two CT reviewers' measurements. • Preoperative evaluation of the CFA in the HRCT accurately predicted the round window accessibility. Patients with CFA less than 25.5
° were expected to have difficult accessibility into the round window during cochlear implantation., (© 2022. The Author(s).)- Published
- 2023
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25. A response to the letter to the editor: facial recess and posterior tympanotomy on CT scans-where we are and what is next?
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Mandour M, Elfarargy HH, Lotfy R, Elsheikh MN, Barbara M, and Elzayat S
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- Humans, Tomography, X-Ray Computed, Middle Ear Ventilation, Temporal Bone surgery
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- 2022
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26. A novel radiological method to evaluate the posterior tympanotomy depth for cochlear implantation: our experience in 257 patients.
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Mandour M, Elfarargy HH, Lotfy R, Elsheikh MN, Barbara M, and Elzayat S
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- Ear, Middle surgery, Humans, Middle Ear Ventilation methods, Radiography, Round Window, Ear surgery, Cochlear Implantation methods, Cochlear Implants
- Abstract
Purpose: This study aimed to validate our novel proposed radiological evaluation of the posterior tympanotomy (PT) depth. This dimension represents the bone of the facial recess needed to be drilled to get access into the middle ear during cochlear implantation., Methods: It was a retrospective observational study that included 257 patients who underwent cochlear implantation from July 2018 to April 2021 in tertiary referral institutions. Two physicians evaluated the preoperative HRCT to measure the PT depth in the oblique para-sagittal cut. On the other hand, two other physicians evaluated the unedited surgical videos to judge the PT depth and classified it into an ordinary PT or deep PT. Then, the preoperative radiological measurements were correlated with the intraoperative findings., Results: The radiological PT depth ranged from 2.5 to 5.4 mm with a mean of 3.91 ± 0.886. Sixty-six patients had ordinary PT, and 191 patients had deep PT. Spearman's correlation coefficient revealed a strong correlation between the preoperative radiological PT depth measurements and the intraoperative PT depth judgments (p value < 0.0001)., Conclusions: We created a novel radiological method to measure the posterior tympanotomy depth. This method was valid, reproducible, and reliable in the preoperative radiological evaluation of the PT depth with high sensitivity (91.71%), specificity (90.62%), and accuracy (91.44%). We also found a significant impact of the PT depth on the PT difficulty during cochlear implantation., (© 2022. The Author(s).)
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- 2022
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27. The Impact of the Location of Chorda Tymapni Nerve Origin on the Round Window Accessibility During Pediatric Cochlear Implantation: A Radioclinical Assessment.
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Elzayat S, Mandour M, Elfarargy HH, Lotfy R, Margani V, Covelli E, and Barbara M
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- Child, Chorda Tympani Nerve surgery, Facial Nerve diagnostic imaging, Facial Nerve surgery, Humans, Round Window, Ear surgery, Temporal Bone surgery, Cochlear Implantation methods, Cochlear Implants
- Abstract
Objectives: This study assessed the impact of the location of the chorda tympani nerve (CTN) origin on the round window (RW) accessibility during pediatric cochlear implantation (CI). We also tried to validate the radiologic method to measure the length between the origin of the CTN from the facial nerve to the stylomastoid foramen (CF-SM)., Study Design: It was a prospective observational case-series study., Settings: The included CI surgeries were performed at tertiary referral institutions from November 2018 to August 2021., Subjects: We included 146 pediatric patients who were candidates for CI., Intervention: We measured the CF-SM length in the parasagittal cut of the preoperative high-resolution computed tomography. We also classified the intraoperative RW according to the accessibility through the ordinary posterior tympanotomy approach into accessible or inaccessible., Main Outcome Measure: We correlated the preoperative radiologic CF-SM length with the intraoperative RW accessibility., Results: The radiologic CF-SM length ranged from 2.9 to 7.4 mm with a mean of 4.9 ± 1.03 mm. The RW was accessible in 107 patients and inaccessible in 39 patients. Spearman's correlation coefficient revealed a significant relationship between the location of CTN origin and the RW accessibility as the p value was less than 0.0001., Conclusions: We found a precise method to measure the CF-SM length in the parasagittal cut of the high-resolution computed tomography. We also found a significant impact of the location of the CTN origin on intraoperative RW accessibility. The radiologic CF-SM length of more than 5.4 mm had a powerful prediction capability of the RW inaccessibility., Competing Interests: The authors disclose no conflicts of interest., (Copyright © 2022, Otology & Neurotology, Inc.)
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- 2022
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28. The Impact of COVID-19 on the Daily Life and Medical Practice of Otolaryngology Physicians.
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Elzayat S, Elfarargy HH, Mandour M, Mahrous A, El-Deeb ME, Barbara M, and Elsherief H
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Introduction The coronavirus disease 2019 (COVID-19) has made otolaryngologists more susceptible than their counterparts to its effect. Objective This study aimed to find if COVID-19 had a different impact on ear, nose, and throat (ENT) physicians' of various categories (residents, registrars, and consultants ) regarding many aspects of the quality of life (protection, training, financial, and psychological aspects). Methods We included 375 ENT physicians, of different categories (residents, registrars, and consultants), from 33 general hospitals and 26 university hospitals in Egypt. The study was conducted using a 20-item questionnaire with a response scale consisting of three categories: yes, no, and not sure. It covered infection control and personal protective equipment (PPE) usage; medical practice and safety; online consultation and telemedicine,; webinars and online lectures; COVID-19 psychological, financial, and quarantine period effects; and future expectations. Results The results of the questionnaire showed that COVID-19 had a statistically significant impact on the daily life of the responders. There were statistically significant differences among the three involved categories, based on their answers. Conclusion This study showed a statistically significant difference regarding the impact of COVID-19 on many aspects of the quality of life (protection, training, financial, and psychological aspects) of ENT physicians of various categories (residents, registrars, and consultants), and these effects may persist for a long time., Competing Interests: Conflict of Interests The authors have no conflict of interests to declare., (Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
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- 2022
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29. The Use of Nanoparticles in Otoprotection.
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Barbara M, Margani V, Covelli E, Filippi C, Volpini L, El-Borady OM, El-Kemary M, Elzayat S, and Elfarargy HH
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The inner ear can be insulted by various noxious stimuli, including drugs (cisplatin and aminoglycosides) and over-acoustic stimulation. These stimuli damage the hair cells giving rise to progressive hearing loss. Systemic drugs have attempted protection from ototoxicity. Most of these drugs poorly reach the inner ear with consequent ineffective action on hearing. The reason for these failures resides in the poor inner ear blood supply, the presence of the blood-labyrinthine barrier, and the low permeability of the round window membrane (RWM). This article presents a review of the use of nanoparticles (NPs) in otoprotection. NPs were recently used in many fields of medicine because of their ability to deliver drugs to the target organs or cells. The studies included in the review regarded the biocompatibility of the used NPs by in vitro and in vivo experiments. In most studies, NPs proved safe without a significant decrease in cell viability or signs of ototoxicity. Many nano-techniques were used to improve the drugs' kinetics and efficiency. These techniques included encapsulation, polymerization, surface functionalization, and enhanced drug release. In such a way, it improved drug transmission through the RWM with increased and prolonged intra-cochlear drug concentrations. In all studies, the fabricated drug-NPs effectively preserved the hair cells and the functioning hearing from exposure to different ototoxic stimuli, simulating the actual clinical circumstances. Most of these studies regarded cisplatin ototoxicity due to the wide use of this drug in clinical oncology. Dexamethasone (DEX) and antioxidants represent the most used drugs in most studies. These drugs effectively prevented apoptosis and reactive oxygen species (ROS) production caused by ototoxic stimuli. These various successful experiments confirmed the biocompatibility of different NPs and made it successfully to human clinical trials., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Barbara, Margani, Covelli, Filippi, Volpini, El-Borady, El-Kemary, Elzayat and Elfarargy.)
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- 2022
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30. What is the most appropriate hemostatic material during pediatric adenoidectomy? A prospective comparative randomized double-blinded controlled study.
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Elzayat S, Elfarargy HH, Soltan I, Aouf M, Elsherif H, Margani V, Covelli E, Volpini L, Lasheen HN, and Barbara M
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- Adenoidectomy adverse effects, Adenoidectomy methods, Blood Loss, Surgical prevention & control, Child, Double-Blind Method, Hemostasis, Humans, Hydrogen Peroxide, Pain, Postoperative etiology, Pain, Postoperative prevention & control, Prospective Studies, Quality of Life, Halitosis, Hemostatics therapeutic use
- Abstract
Objectives: To evaluate the effect of different hemostatic materials used in adenoidectomy operations to improve the quality of life with the most negligible hazardous impact on pediatric health., Study Design: a prospective, case-series, randomized, controlled, double-blinded study., Setting: All adenoidectomy surgeries were performed between September 2016 to December 2019 at tertiary referral institutions., Patients and Methods: 519 patients were included in five groups. Adenoidectomy was performed under general anesthesia, with the following hemostatic procedures: adrenaline, tranexamic acid, hydrogen peroxide, xylometazoline, and saline (as a control group). The five groups were compared regarding the intraoperative blood loss, surgery duration, need for more hemostatic steps, postoperative reactionary and secondary bleedings, postoperative pain and halitosis, and one-year outcome., Results: The four procedures were effective in reducing the blood loss by 19.86%, 11.7%, 30.95%, and 18.91%, respectively, in comparison to the control group. The surgical duration was reduced by 27.65%, 17.86%, 48.11%, and 23.88%, respectively. The need for other hemostatic steps was the least in the hydrogen peroxide group. There was no significant difference between the five groups regarding reactionary bleeding, secondary bleeding, one-week pain, one-month pain, one-month halitosis, and one-year complications. On the other side, hydrogen peroxide had the least one-week halitosis and first-day pain among the five groups. Also, it had the least intraoperative blood loss and surgery duration., Conclusions: Hydrogen peroxide showed to be the best choice to control hemostasis during an adenoidectomy. It can decrease blood loss and surgery duration with less need for other hemostatic steps. It can improve the patient's quality of life without significant postoperative complications. Xylometazoline was studied for the first time as a hemostatic material during adenoidectomy with good satisfying results., (Copyright © 2022 Elsevier B.V. All rights reserved.)
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- 2022
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31. Efficacy, predictors of success and failure of an updated lateral pharyngoplasty approach as an independent procedure in treating obstructive sleep apnea with CPAP failures.
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Elsobki A, Moussa HH, Eldeeb ME, Fayed A, and Elzayat S
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- Humans, Polysomnography, Snoring, Treatment Outcome, Pharynx surgery, Sleep Apnea, Obstructive surgery
- Abstract
Purpose: To assess predictors of success and failure of an updated lateral pharyngoplasty as an independent procedure in treating obstructive sleep apnea with CPAP failures., Methods: Forty-six patients with known OSAS who were resistant to CPAP or failures were included. BMI, Stop-Bang score, and sleep study data were recorded before and after the updated Cahali pharyngoplasty procedure. Pre-operative DISE was done for all cases; however, postoperative DISE was done only for non-responders., Results: Successful operation outcomes achieved in 69.6% (32 cases) and 30.4% (14 cases) were failure rates. Postoperative snoring index, Stop Bang score, and AHI were significantly decreased compared to pre-operative data (p value < 0.001). There is statistically a significant increase in minimal and baseline SpO
2 postoperatively (p value < 0.001). Patients with no laryngeal collapse (L0) predict operation success. However, patients with high pre-operative snoring index, collapse at lateral wall hypopharynx, high tongue collapse, laryngeal collapse, tongue palate interaction, and low grades tonsils (1, 2) predict the failure of the surgery (p value = 0.006*,0.024*,0.047*, respectively)., Conclusion: Updated Cahali lateral pharyngoplasty could not be used as an independent procedure in all OSA patients. The lack of laryngeal collapse (L0) is a considerable success predictor for the procedure. However, the pre-operative low-grade tonsils (1, 2) and high snoring index predict operation failure., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)- Published
- 2022
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32. The impact of bolgerization versus partial resection of the middle turbinate on frontal sinusotomy patency outcome: A randomised controlled study.
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Khafagy Y, Ghonim M, Elgendy A, and Elzayat S
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- Adult, Chronic Disease, Constriction, Pathologic, Endoscopy, Female, Humans, Male, Prognosis, Airway Obstruction surgery, Frontal Sinusitis surgery, Turbinates surgery
- Abstract
Objectives: This study aimed to compare the effects of middle turbinate resection vs bolgerization on the incidence of middle meatus synechia and their prognostic value on the patency outcomes after frontal sinusotomy., Design: A randomised controlled study., Setting: Tertiary centre hospital., Main Outcome Measures: Thirty-eight patients undergoing bilateral frontal sinusotomy for chronic frontal sinusitis were included. Partial middle turbinate resection was alternated with bolgerization in both nasal cavities of every patient. The Lund-Kennedy endoscopic scores (LKESs) for both sides were compared at the first, third and sixth months postoperatively. Middle meatus synechia was assessed using the visual analogue score (VAS). Sinus patency was assessed at the end of the sixth month using a 70° nasal endoscope., Results: The sinus patency outcome was significantly higher in the resected group (34\38) than the bolgerized group (26\38), (P = .047*). The VAS scores suggested that the middle turbinate bolgerization group showed a significantly higher incidence of middle meatal synechia than the partial middle turbinate resection group (4.47 ± 2.617 vs 3.29 ± 2.301; P = .040*)., Conclusion: Middle turbinate resection showed more favourable results than bolgerization concerning the sinus patency outcome after frontal sinusotomy. It also showed a lower incidence of middle meatus synechia postoperatively., (© 2021 John Wiley & Sons Ltd.)
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- 2021
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33. Radiological classification of the mastoid portion of the facial nerve: impact on the surgical accessibility of the round window in cochlear implantation.
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Mandour M, Elzayat S, Elfarargy HH, Lotfy R, and ELnaggar A
- Subjects
- Child, Child, Preschool, Facial Nerve anatomy & histology, Female, Humans, Male, Retrospective Studies, Cochlear Implantation methods, Facial Nerve diagnostic imaging, Mastoid diagnostic imaging, Round Window, Ear, Tomography, X-Ray Computed
- Abstract
Background: Mastoid portion of the facial nerve plays an important role in the round window approach of cochlear implantation., Objectives: This study aimed to predict the anterior displacement of the mastoid portion of the facial nerve in the preoperative HRCT coronal cuts. We also aimed to detect the implication of anterior displacement of MPFN on the R.W. accessibility through the posterior tympanotomy during cochlear implantation., Materials and Methods: It was a retrospective observational cohort study in tertiary referral hospitals. We included 246 pediatric patients who underwent cochlear implantation due to bilateral severe to profound SNHL through a posterior tympanotomy approach., Results: Type I MPFN was present in 84 cases, type II MPFN was present in 149 patients, and type III MPFN was present in 13 cases. R.W. was inaccessible in 3 cases with MPFN type II and in 11 subjects with MPFN type III. There was a statistically significant difference regarding the R.W. accessibility between the three types of MPFN ( p -value <.05). There was a strong statistically significant correlation between R.W. accessibility and the radiological type of the MPFN., Conclusion: Mandour radiological classification of the mastoid portion of the facial nerve in the preoperative HRCT coronal offers an easily applicable method to detect the anterior displacement of the facial nerve by using easy and well-known landmarks. This classification can also predict R.W. accessibility through posterior tympanotomy during cochlear implantation with 97.97% accuracy.
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- 2021
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34. The role of high-resolution Computer Tomography in prediction of the round window membrane visibility and the feasibility of the round window electrode insertion.
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Elzayat S, Soltan I, Talaat M, and Fouad YA
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- Computers, Feasibility Studies, Humans, Retrospective Studies, Round Window, Ear diagnostic imaging, Round Window, Ear surgery, Temporal Bone surgery, Tomography, X-Ray Computed, Cochlear Implantation, Cochlear Implants
- Abstract
Objective: The aim of this work is to assess the role of pre-operative high-resolution computerized tomography (HRCT) in prediction of the round window membrane (RWM) visibility and the feasibility of round window electrode insertion., Materials and Methods: Retrospective study on a series of 97 cases of cochlear implant (CI) who were implanted in tertiary referral centers. We reviewed HRCT of all cases, and we implicated two radiological measurements on HRCT which are membrano-facial angle (MFA) and length of the bony overhang of the round window niche (RWN). We reviewed the intra-operative surgical video recordings of all cases for detection of the type of RWM visibility, according to The St Thomas' Hospital classification., Results: The MFA was 21.9 ± 14.5. The length of the bony overhang of the RWN was 2.4 ± 0.33 mm. About 37% of the studied patients needed cochleostomy. The best cut-off of MFA in the prediction of the RW (type 2B and 3) was ≥ 15.1o with sensitivity 100%, and specificity 82%., Conclusion: HRCT offers highly reliable and reproducible measurements for the prediction of RWM visibility and, therefore, prediction of the utility of the RW approach for electrode insertion. Membrano-facial angle (MFA) is a new measurement that can be used for this purpose., (© 2020. Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2021
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35. Comparison between the endoscopic scores of bolgerization versus partial resection of the middle turbinate for management of the postoperative lateralization in the early follow-up period after endoscopic frontal sinusotomy: A randomized controlled study.
- Author
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Khafagy Y, Ghonim M, Elzayat S, and Elgendy A
- Subjects
- Adult, Chronic Disease, Endoscopy adverse effects, Female, Follow-Up Studies, Humans, Male, Middle Aged, Nasal Surgical Procedures adverse effects, Postoperative Complications etiology, Postoperative Complications pathology, Prospective Studies, Time Factors, Treatment Outcome, Turbinates pathology, Young Adult, Endoscopy methods, Frontal Sinus surgery, Frontal Sinusitis surgery, Nasal Surgical Procedures methods, Postoperative Complications surgery, Turbinates surgery
- Abstract
Background: Frontal sinusotomy is a challenging procedure that needs meticulous handling due to its unique anatomical position. Postoperative middle turbinate lateralization is critical comorbidity for the success rate, and many techniques are adopted to prevent it. The study aimed to compare the effect of middle turbinate bolgerization and partial resection on the postoperative endoscopic scores and assess their impact on the middle meatus and the frontal recess outcome., Patient and Methods: This prospective study was conducted on forty-one patients undergoing bilateral frontal sinusotomy for chronic frontal sinusitis. Nasal cavities were randomized so that partial middle turbinate resection technique was done alternately with bolgerization approach in every patient. Each participant acted as their control. Both sides were compared using Lund Kennedy Endoscopic Score (LKES) and Perioperative Sinus Endoscopy Score (POSE) at the baseline, 1st, 3rd, and 12th-month intervals postoperatively. Also, middle turbinate status was assessed at the end of the 12th-month interval using POSE score., Results: The total frontal sinus patency rate was 82.9% (63/76 operated sinus). Baseline scores, LKES (3.79 ± 0.777 vs 4.05 ± 0.769, p = 0.142, for the side of resection and the side for bolgerization respectively) and POSE (1.79 ± 0.413 vs 1.82 ± 0.393, p = 0.777, for the side of resection and the side for bolgerization respectively). Regarding LKES, the differences between both operated sides were fluctuating with p values: 0.001*, 0.171, and 0.044* for the 1st, 3rd, and 12th months follow-up intervals, respectively. Regarding the POSE score of the frontal sinus, the difference between both groups was steadily increasing with p values: 0.318, 0.119, and 0.017* for the 1st, 3rd
, and 12th months follow-up intervals. The middle turbinate's POSE score at the 12th month was significantly higher in the side allocated for bolgerization (p-value = 0.008*)., Conclusion: Partial middle turbinate resection showed favorable endoscopic outcomes than bolgerization at the 12th month follow up period in patients undergoing primary ESS for chronic frontal sinusitis., (Copyright © 2021 Elsevier Inc. All rights reserved.)- Published
- 2021
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36. The prognostic variables affecting the frontal sinusotomy patency outcome and how to manage: A prospective study.
- Author
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Khafagy Y, Ghonim M, Elgendy A, and Elzayat S
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- Adult, Female, Humans, Male, Prognosis, Prospective Studies, Endoscopy methods, Frontal Sinusitis surgery
- Abstract
Objectives: The study aimed to assess the factors affecting the frontal sinus patency after endoscopic frontal sinusotomy., Design: A prospective cohort study., Setting: Tertiary centre hospital., Main Outcome Measures: Fifty patients with refractory chronic frontal sinusitis (83 operated frontal sinuses) had frontal sinusotomy and followed up for six months. Multiple operative factors were included the type of the procedure, intraoperative sinus findings, degree of mucosal preservation and middle turbinate stability. Other factors were also assessed, including smoking, the presence of allergic rhinitis, asthma, gastroesophageal reflux and other associated medical comorbidities., Results: The sinus patency success rate was 75.9%. There was a significant difference regarding the intraoperative anteroposterior sinus ostium diameter (5.36 ± 1.45 mm vs 8.88 ± 2.38 mm, P-value: .001* in the failed group and the success group, respectively). There was a significant association between the patency outcome and the presence of associated medical comorbidities (P-value: .001*), the presence of allergic rhinitis (P-value: .001*), the degree of sinus mucosal preservation (P-value: .012*) and the degree of middle turbinate stability (P-value: .001*). The multivariate analysis showed that the intraoperative anteroposterior diameter of the sinus ostium, middle turbinate stability and presence of allergic rhinitis were significant predictors (P-value: .012*, .042* and .013*, respectively)., Conclusion: Sinuses with anteroposterior ostium diameters less than 5.36 mm are more susceptible to restenosis. The flail middle turbinate increases the risk of postoperative middle meatus synechia and frontal sinus patency failure. The presence of allergic rhinitis has a negative impact on the patency outcome., (© 2021 John Wiley & Sons Ltd.)
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- 2021
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37. Morphological classification of crista fenestra of round window corridor during pediatric cochlear implantation.
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Elzayat S, Elfarargy HH, Soltan I, Abdel-Kareem MA, Barbara M, Fayed A, and Baki F
- Subjects
- Child, Cohort Studies, Humans, Prospective Studies, Round Window, Ear surgery, Cochlear Implantation, Cochlear Implants
- Abstract
Objectives: This study aimed to document the observation of the Crista Fenestra's morphological types (CF) of the round window and to detect its impact during cochlear implant operation., Study Design: A prospective descriptive cohort study., Settings: We conducted this study at tertiary referral institutions in Egypt., Patients: This study included 140 children who underwent cochlear implantation., Intervention: We observed the CF's morphological type during the operation according to (Baki-Elzayat) novel classification of CF anatomy, and the need for drilling in each CI operation., Main Outcome Measures: CF has two main types. Type A, in which CF was present at the same level of round window membrane and attached to it. Type B, in which CF was medial to the Round window membrane., Results: Type (A) CF was detected in 125 cases (89.28%), while 25 cases (10.71%) showed type (B) CF. Drilling was needed in 10 cases (7.14%), including CF types A.3 and B2. Drilling was not needed in 130 cases (92.85%), including CF type A.1, A.2, and B.1. There was a statistically significant difference in the need for drilling (P-value <0.001)., Conclusions: According to this prospective study, CF had complicated anatomy. Baki-Elzayat classified the CF into two main types. In type A, CF was at the same level of RWM and attached to it. In type B, CF was medial to RWM. We recommended drilling for partial removal of massive CF types (A.3 and B.2) for atraumatic safe insertion of the electrode without deflection. This classification can offer an easy language system for CI surgeons to describe and register CF during their operations and in the surgical files., (Copyright © 2021 Elsevier B.V. All rights reserved.)
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- 2021
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38. Otitis media with effusion is not a sterile inflammatory process: scanning electron microscope evidence.
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Elzayat S, Nosair N, Ghazy AA, and Abdulghaffar IA
- Subjects
- Biofilms, Case-Control Studies, Child, Ear, Middle, Humans, Microscopy, Electron, Scanning, Otitis Media complications, Otitis Media with Effusion diagnosis
- Abstract
Purpose: We aimed to demonstrate whether chronic otitis media with effusion (OME) is a sterile condition or biofilms-related disease through direct visualization of middle ear mucosa by Scanning electron microscopy (SEM) and culture of the effusion., Methods: This case-control study included 60 children in two groups; the case group included 50 patients undergoing ventilation tube insertion (VTI) for Chronic OME (COME), and the control group included ten patients undergoing cochlear implantation (CI) surgery presenting normal middle ear mucosa. Biopsies from both groups' middle ear mucosa were evaluated for biofilm formation using scanning electron microscopy (SEM). Middle ear effusion (MEE) samples from COME patients were cultured on blood agar to detect and identify any bacterial growth. The adenoid size was evaluated and correlated to the biofilm formation in COME patients., Results: There was a significant difference between case and control groups regarding biofilm formation (p-value < 0.001*). Biofilm was evident in 84% of the COME patients (cases group) and absent in the control group. Only 12 COME patients (24%) had positive MEE culture, however, 76.2% of patients with biofilm had a negative culture. Streptococcus pneumonia was the most common otopathogen found either alone or combined with other otopathogens. There was a significant negative correlation between adenoid size and biofilm grade among the studied patients., Conclusion: The visual identification of middle ear biofilms indicated their role in chronic OME. Middle ear biofilms need to be expected in children with OME, especially those who do not need adenoid surgery.
- Published
- 2021
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39. Trans-oral endoscopic assisted radio-frequency for adenoid ablation; A randomized prospective comparative clinical study.
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Elzayat S, Elsherif H, and Aouf M
- Subjects
- Adenoidectomy adverse effects, Adolescent, Blood Loss, Surgical, Child, Child, Preschool, Curettage adverse effects, Curettage methods, Endoscopy methods, Female, Humans, Male, Pain, Postoperative, Prospective Studies, Radiofrequency Ablation adverse effects, Adenoidectomy methods, Adenoids surgery, Radiofrequency Ablation methods
- Abstract
Objective: This study compared the efficacy and safety of conventional adenoidectomy using a curette and the Radio-frequency (RF) adenoid ablation using endoscope via the trans-oral technique., Methods: A randomized prospective comparative study was conducted in a tertiary care hospital. The study included 80 patients with a diagnosis of adenoid hypertrophy, which was confirmed by X-ray of a lateral view of the skull. The patients were submitted into two groups 40 for each: curettage group and Radiofrequency group. Patients with bleeding diathesis, congenital anomalies, previous adenoidectomy, and morbid illness were excluded from the study. We evaluated the time consumption, the adenoid tissue remnant by the endoscope, blood loss, and clinical correlations like pain by Visual Analog Scale, halitosis, and secondary bleeding in both study groups., Results: Intra-operative blood loss was 20-40 ml in the Radio-frequency (RF) group, but in the curettage group was 36 - 55 ml. Post-operative pain in the (RF) group was lower than the curettage group. Secondary bleeding was reported mostly in the curettage group (15%). The duration of the operation in (RF) group was relatively long. Halitosis decreased mainly after curettage adenoidectomy., Conclusion: The endoscopic radio-frequency adenoid ablation surpassed the conventional method. We encourage using Radio-frequency in adenoid surgery as a replacement for the traditional method., Competing Interests: Declaration of Competing Interest There is no conflict of interest, (Copyright © 2020. Published by Elsevier B.V.)
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- 2021
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40. Arabic Cross-Cultural Adaptation and Validation of Health-Related Quality of Life Measures for Chronic Otitis Media (COMQ-12).
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Elzayat S, Elfarargy HH, Mandour M, Lotfy R, and Barbara M
- Subjects
- Cohort Studies, Cross-Cultural Comparison, Humans, Language, Prospective Studies, Psychometrics, Reproducibility of Results, Surveys and Questionnaires, Otitis Media surgery, Quality of Life
- Abstract
Objective: Our study aimed to translate the chronic otitis media questionnaire-12 (COMQ-12) into the Arabic language, evaluate the internal consistency of the test and test-retest reliability, and validate the adaptation for further use in Arabic studies., Study Design: A prospective observation monocenter cohort study., Settings: This study was done at Kafrelsheikh University Hospital, Egypt., Patients: One hundred twenty five ear pathology-free patients were asked to complete the questionnaire forming group A. One hundred twenty five patients with different forms of COM completed the questionnaire 2 weeks before the planned ear surgery and the same day of the operation, forming group B. Those patients who underwent the ear surgery, completed the questionnaire again 6 months after the operation forming group C., Intervention: We did an Arabic forward and backward translation of the original COMQ-12. The patients in group B underwent ear surgery (tympanoplasty with or without mastoidectomy). After fulfilling the questionnaire in different groups, we assessed the psychometric properties of the Arabic version of COMQ-12: internal consistency, reliability, reproducibility, validity, and responsiveness., Main Outcome Measures: Cronbach's α was 0.973. The Spearman's rank correlation coefficient was 0.981, while the Intraclass correlation coefficient was 0.973., Results: A statistically significant difference was present between group A (average total score 2.38 ± 1.543) and group B (average total score 35.86 ± 5.98). Also, there was a statistically significant difference between group B and group C (average total score 7.46 ± 8.294). The calculated cut-off point of the total score was more than or equal to eight., Conclusion: The cross-culturally Arabic adaptation of COMQ-12 was reliable, valid with strong internal consistency and responsiveness. It can detect the significant effect of COM on the quality of life of Arabic patients. This effect would be improved obviously after surgical management that markedly enhanced the preoperative hearing problem., Competing Interests: The authors disclose no conflicts of interest., (Copyright © 2021, Otology & Neurotology, Inc.)
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- 2021
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41. The preoperative radiological findings associated with failure of frontal sinusotomy: A prospective study.
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Khafagy Y, Ghonim M, Elgendy A, and Elzayat S
- Subjects
- Adult, Chronic Disease, Endoscopy, Female, Humans, Male, Preoperative Care, Prospective Studies, Risk Factors, Treatment Failure, Frontal Sinusitis diagnostic imaging, Frontal Sinusitis surgery, Tomography, X-Ray Computed
- Abstract
Objectives: The study aimed to assess the association between the preoperative CT findings and the patency outcome of the frontal sinus after endoscopic frontal sinusotomy in the early follow-up period., Design: A prospective cohort study., Setting: Tertiary hospital centre., Main Outcome Measures: The study measures the association between the frontal sinusotomy outcome and the standard preoperative radiological scores, including Harvard, Kennedy and Lund-Mackay. It also measures the impact of the degree of sinus mucosal thickness on the outcome. Furthermore, it measures the effect of the anteroposterior lengths of both the frontal sinus ostium and the frontal recess on postoperative frontal sinus patency., Results: Harvard, Kennedy and modified Lund-Mackay scores showed no evidence of association with the frontal sinusotomy patency outcome (P-values .397, .487 and .501), respectively. Still, the Lund-Mackay score showed a negative correlation with symptom improvement. Sinuses with a high-grade mucosal thickness on CT scan were associated with high failure rates (P-value: .009*). The anteroposterior length of the frontal sinus ostium significantly affects the outcome (P-value: .001*). In contrast, there was no association between the anteroposterior length of the frontal recess and the outcome (P-value: .965)., Conclusion: The Harvard, Kennedy and Lund-Mackay scores could not predict the frontal sinusotomy patency outcome. Failed cases were associated with advanced degrees of mucosal pathology in the preoperative CT scan. Sinuses ostia with anteroposterior diameters less than 5.36 mm showed more susceptibility for sinus restenosis postoperatively. The variability of the anteroposterior length of the frontal recess did not affect the surgical outcome., (© 2021 John Wiley & Sons Ltd.)
- Published
- 2021
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42. The Pattern of Anosmia in Non-hospitalized Patients in the COVID-19 Pandemic: A Cross-sectional Study.
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Elsherief H, Amer M, Abdel-Hamid AS, El-Deeb ME, Negm A, and Elzayat S
- Abstract
Introduction It is now evident that the loss of smell and/or taste may be consistent accompanying symptoms of the SARS-CoV-2 infection. Objective To estimate the social behavior of recent anosmic non-hospitalized patients in the COVID-19 pandemic and to try to obtain the natural pattern in society in a cross-sectional study. Methods A cross-sectional study conducted on 4,860 patients with anosmia complaints during the COVID-19 pandemic. Patients who needed a consultation for an anosmia complaint confirmed that they had completed the survey regarding age, gender, history of general diseases, history of nasal disease, associated COVID-19 symptoms, smoking, blood group, and risk factors. Results A total of 4,860 patients with a mean age of 34.26 ± 11.91 years completed the study. There was a predominance of female patients: 3,150 (58.9%). Most patients (4,083 patients; 83%) developed sudden anosmia. In 85% (4131 patients) of the patients, a previous history of contact with anosmic patients was present. The most prevalent blood group was O (39%). In total, 67.4% of the patients underwent medical treatment. A history of unusual influenza attacks in December 2020 was reported by by 27% (1312 patients) of the patients. Conclusion Despite large diversity of behaviors among anosmic patients in the COVID-19 pandemic, we can observe a great similarity in the pattern of anosmia in non-hospitalized patients, especially in the way it spreads, the predisposing factors, and the individual recovery., Competing Interests: Conflict of Interests The authors have no conflict of interests to declare., (Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ).)
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- 2021
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43. Correlation of Preoperative Computerized Tomography Scoring System and the Surgical Encounters in Cochlear Implantation.
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Elzayat S, Mandour M, Elfarargy H, Lotfy R, Soltan I, and Mahrous A
- Subjects
- Child, Face, Humans, Retrospective Studies, Tomography, X-Ray Computed, Cochlear Implantation
- Abstract
Objective: To propose a numerical radiological scoring system of the pre-operative high-resolution computed tomography scan aiming to predict the surgical difficulty during cochlear implantation., Methods: This was a retrospective study of 272 pediatric patients who underwent cochlear implantation in 3 tertiary referral centers from April 2017 to August 2019. The correlation was attempted between our proposed scoring system (consisting of 8 radiological features) and the intraoperative surgical difficulty both objectively and subjectively., Results: our proposed scoring system showed a statistically significant correlation with surgical difficulty and also the duration of surgery. Scoring 5 or more predicted the surgical difficulty with a sensitivity of 80.85% and a specificity of 92.13%. The absence of air cells around the facial recess was the most independent predictor of difficulty (P value = .002)., Conclusion: This proposed radiological scoring system is a simple reliable method to predict the difficulty which we may encounter during CI surgery. Scoring of 5 or more would predict intraoperative difficulty as opposed to less scoring which would predict a straightforward surgery.
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- 2021
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44. Management of bilateral abductor paralysis: posterior cordectomy with partial arytenoidectomy using diode laser.
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El-Sobki A, El-Deeb ME, El-Kholy NA, and Elzayat S
- Subjects
- Arytenoid Cartilage surgery, Humans, Lasers, Semiconductor therapeutic use, Vocal Cords surgery, Laser Therapy, Vocal Cord Paralysis surgery
- Abstract
Purpose: This study aims to assess the role of diode laser-assisted posterior cordectomy with partial arytenoidectomy in the management of bilateral vocal fold paralysis patients., Methods: Posterior cordectomy with partial arytenoidectomy using diode laser was performed to thirty-nine patients with bilateral vocal fold paralysis. Voice was evaluated by maximal phonation time and Arabic version of the voice handicap index, while breathing difficulty was assessed by mMRC (Modified Medical Research Council) dyspnea scale., Results: There is a statistically significant decrease in mMRC from 2.8 ± 0.645 preoperatively to 0.84 ± 0.554 postoperatively (p < 0.001). However, maximum phonation time is significantly decreased from 8.04 ± 0.978 preoperatively to 6.92 ± 0.997 postoperatively (p < 0.001); there is a statistically non-significant increase in vocal handicap index from 37.12 ± 6.26 preoperatively to 37.24 ± 6.22) postoperatively (p > 0.05)., Conclusions: The diode laser is a viable method that should be considered for the management of bilateral vocal cord paralysis. It seems to be a very promising laser device, so we expect that new diode laser wavelengths (980 nm) will continue to emerge, making it a good alternative to the CO
2 laser, but with lower cost, accurate manipulation, portability, shorter duration, and simplicity of use., Level of Evidence: 4.- Published
- 2021
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45. The safety of posterior tympanotomy in otitis media with effusion during cochlear implantation: clinical retrospective cohort study.
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Elzayat S, Nada I, El Sherif H, and Mahrous A
- Subjects
- Child, Preschool, Cochlear Implants, Female, Follow-Up Studies, Humans, Infant, Intraoperative Period, Male, Otitis Media with Effusion diagnosis, Postoperative Period, Retrospective Studies, Tomography, X-Ray Computed, Tympanic Membrane diagnostic imaging, Cochlear Implantation methods, Otitis Media with Effusion surgery, Tympanic Membrane surgery
- Abstract
Background: Posterior tympanotomy (PT) is an important step in cochlear implant (CI) surgery, as it is the main access to the round window. Some CI candidates, especially children, may have concomitant otitis media with effusion (OME) which may result in technical issues during PT. There is still a debate whether to wait for OME resolution preoperatively or to proceed to surgery with suspected difficulties., Aims/objective: To evaluate the safety of PT during CI surgery in patients with OME., Material and Methods: we included 102 consecutive pediatric candidates in this retrospective study with an age range of 12 months to 6 years. All the patients underwent CI surgery using trans-mastoid, PT to access round window (RW) area. We investigated the effect of the pathology caused by OME on the operative procedure in PT and post-operative consequences., The Results: out of 102 patients included in this study, there were 22 patients with OME who had unilateral cochlear implantation with no major operative or post-operative events. Nevertheless, some minor intra operative events and difficulties were encountered., Conclusion and Significance: The presence of OME in CI surgery indicates possible surgical challenges such as difficult PT, minor intra-operative risks and with no major post-operative events.
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- 2021
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46. Early recovery patterns of olfactory disorders in COVID-19 patients; a clinical cohort study.
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Amer MA, Elsherif HS, Abdel-Hamid AS, and Elzayat S
- Subjects
- Adult, COVID-19, Cohort Studies, Cross-Sectional Studies, Female, Fever virology, Humans, Male, Middle Aged, Pandemics, SARS-CoV-2, Time Factors, Young Adult, Betacoronavirus, Coronavirus Infections complications, Olfaction Disorders virology, Pneumonia, Viral complications, Recovery of Function
- Abstract
Introduction: A rapidly evolving evidence suggests that smell dysfunction is a common symptom in COVID-19 infection with paucity of data on its duration and recovery rate., Objectives: Delineate the different patterns of olfactory disorders recovery in patients with COVID-19., Methods: This cross-sectional cohort study included 96 patients with olfactory complaint confirmed to be COVID-19 positive with recent onset of anosmia. All patients were inquired for smell recovery patterns using self-assessment questionnaires., Results: Ninety six patients completed the study with mean age 34.26 ± 11.91 years. Most patients had sudden anosmia 83%. Loss of smell was accompanied by nonspecific inflammatory symptoms as low-grade fever (17%) and generalized body ache (25%). Nasal symptoms were reported by 33% of patients. Some patients reported comorbidities as D.M (16%), hypertension (8%) or associated allergic rhinitis (25%), different patterns of olfactory recovery showed 32 patients experiencing full recovery (33.3%) while, 40 patients showed partial recovery (41.7%) after a mean of 11 days while 24 patients (25%) showed no recovery within one month from onset of anosmia., Conclusion: The sudden olfactory dysfunction is a common symptom in patients with COVID-19. Hyposmia patients recover more rapidly than anosmic ones while the middle age group carried the best prognosis in olfactory recovery. Females possess better potentiality in regaining smell after recovery and the association of comorbidities worsen the recovery rate of olfactory dysfunction in patients with COVID19., Level of Evidence: Level 2b a cross-sectional cohort study., (Copyright © 2020 Elsevier Inc. All rights reserved.)
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- 2020
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47. Validation and adaptation of the Arabic version of the Tonsil and Adenoid Health Status Instrument.
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Elzayat S, Elfarargy H, Kabbash IA, Nada I, Mehanna AM, and Elsherief HS
- Subjects
- Adenoidectomy, Child, Child, Preschool, Female, Humans, Language, Male, Prospective Studies, Psychometrics, Reproducibility of Results, Translations, Treatment Outcome, Health Status, Quality of Life, Surveys and Questionnaires, Tonsillectomy
- Abstract
Objectives: Validation and cross-cultural adaptation of the Tonsil and Adenoid Health Status study tool, in Arabic while studying its psychometric properties., Study Design: prospective -validation study., Settings: Multiple tertiary centers., Patients/and Other Participants: 63 consecutive patients who underwent tonsillectomy or adenotonsillectomy operation (pre-operative and 6 months post-operative) and 65 asymptomatic controls., Intervention/methods: FOLLOWING: Guidelines for the cross-cultural adaptation process, to translate the original English language version into an Arabic language one., Main Outcome Measures: We assessed the psychometric properties of the Arabic version of the TAHSI (A-TAHSI) its feasibility, reproducibility, internal consistency, reliability, discriminatory validity and responsiveness to change., Results: The Mann-Whitney test showed a statistically significant difference for the mean score between the patients and the control group denoting good clinical validity. The Cronbach's coefficient value for the A- TAHSI for 63 cases was 0.983, demonstrating good internal consistency. The Wilcoxon signed-rank test showed a marked improvement in the patients' scores 6 months post-operatively. Spearman's rank and Pearson's correlations were used to correlate the level of resemblance of the mean score of the A-TAHSI, which showed statistically significant results., Conclusions: The A-TAHSI is a valid instrument for evaluating the subjective effect of tonsillectomy on the health and quality of life and hence is recommended to be used in tonsillectomy research and daily practice., Level of Evidence: 3b., (Copyright © 2020 Elsevier B.V. All rights reserved.)
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- 2020
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48. The safety of bipolar mode radiofrequency (BMRF) on cochlear implant integrity test; a clinical prospective study.
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Elzayat S, Elsherif H, Nada I, and Youssef R
- Subjects
- Child, Child, Preschool, Electric Impedance, Female, Humans, Male, Prospective Studies, Prosthesis Failure etiology, Radiofrequency Ablation instrumentation, Safety, Surgical Instruments, Tonsillectomy adverse effects, Cochlear Implants, Negative Results, Prosthesis Failure radiation effects, Radiofrequency Ablation adverse effects, Radiofrequency Ablation methods, Tonsillectomy methods
- Abstract
Purpose: We aimed to assess the effect of bipolar mode radiofrequency (BMRF) tonsillectomy as a model of oro-pharyngeal surgical maneuver on the integrity of the internal device in patients with cochlear implants (CIs)., Materials and Methods: This prospective case series included 15 consecutive pediatric patients with CIs (age range 4 to 8 years, mean 5.2 years) who underwent BMRF tonsillectomy. The postoperative integrity of the internal device was evaluated by comparing the electric current response tested preoperatively with that tested 2 days postoperatively., Results: There were differences in the current levels in the main regions of the cochlea; (the apical, mid-turn, and basal) after comparing preoperative and postoperative values, but they were not statically significant., Conclusion: BMRF seems to be safe for tonsillectomy in children with CIs without negative impact on the integrity of the internal device., Competing Interests: Declaration of competing interest There is no conflict of interest., (Copyright © 2020 Elsevier Inc. All rights reserved.)
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- 2020
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49. ENT manifestation in COVID-19 patients.
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El-Anwar MW, Elzayat S, and Fouad YA
- Subjects
- Adenoids, Betacoronavirus, COVID-19, Cough physiopathology, Diarrhea physiopathology, Dyspnea physiopathology, Erythema physiopathology, Fatigue physiopathology, Fever physiopathology, Headache physiopathology, Humans, Myalgia physiopathology, Nasal Obstruction physiopathology, Otorhinolaryngologic Diseases physiopathology, Palatine Tonsil, Pandemics, Respiratory Tract Infections physiopathology, SARS-CoV-2, Coronavirus Infections physiopathology, Olfaction Disorders physiopathology, Pharyngitis physiopathology, Pneumonia, Viral physiopathology
- Abstract
Objective: to detect, analyze and discuss the different ear nose throat (ENT) manifestations those were reported in COVID19 positive patients in the reviewed and published literatures., Methods: We performed a search in the PubMed databases, Web of Science, LILACS, MEDLINE, SciELO, and Cochrane Library using the keywords; COVID-19, Novel coronavirus, corona, 2019-nCoV, SARS-CoV-2, ENT, ear, nose, throat, otorhinolaryngology, ORL, pharynx, ORL, smell, larynx, different ENT related symptoms. We reviewed published and peer reviewed studies that reported the ENT manifestations in COVID-19 laboratory-confirmed positive patients., Results: within the included 1773 COVID-19 laboratory-confirmed positive patients, the most common ENT manifestations of COVID-19 were sore throat (11.3%) and headache (10.7%). While the other reported ENT manifestations were pharyngeal erythema (5.3%), nasal congestion (4.1%), runny nose or rhinorrhea (2.1%), upper respiratory tract infection (URTI) (1.9%), and tonsil enlargement (1.3%)., Conclusion: ENT manifestations for COVID-19 are not common as fever and cough. But, a universal questionnaire using well-defined COVID-19 manifestations is needed to make the COVID-19 data precisely defined, complete and homogenous., Competing Interests: Declaration of Competing Interest The authors declare no conflict of interest and do not have any potential financial conflict of interest related to or could influence this work., (Copyright © 2020. Published by Elsevier B.V.)
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- 2020
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50. Managing obstructive sleep apnea patients with CPAP failure with a novel Lateral Pharyngoplasty as a stand-alone procedure.
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Elzayat S, El-Sobki A, El-Deeb ME, and Moussa HH
- Subjects
- Female, Humans, Male, Sleep Apnea, Obstructive therapy, Treatment Outcome, Pharynx surgery, Plastic Surgery Procedures methods, Sleep Apnea, Obstructive surgery
- Abstract
Background: Obstructive sleep apnea syndrome (OSAS) is caused by a complete or partial obstruction of the upper airway. A new Cahali lateral pharyngoplasty as a stand-alone procedure for the treatment of OSA patients, whatever the level and pattern of airway obstruction in patients with CPAP failure or non-compliant patients, is it?, Patients and Methods: 40 patients with known OSAS non-compliant with CPAP or CPAP failures included. BMI, Stop-Bang score, and sleep study parameters were reported before and after the new Cahali pharyngoplasty operation. Preoperative DISE was done for all cases., Results: There were 28 (70%) cases with successful operation outcomes, and 12 (30%) failed cases. Postoperative Stop Bang score, AHI, snoring index were significantly reduced in comparison to preoperative data (p-value <0.001); however, minimal SpO
2 and baseline SpO2 were significantly increased in comparison to preoperative data. There was a significant improvement in AHI postoperative. Patients collapse at the level of lateral wall hypopharynx, high tongue collapse, laryngeal collapse, tongue palate interaction, all significantly predict failure outcome of the operation (p-value = 0.022). However, the absence of laryngeal collapse (L0) had a successful prediction outcome. The high snoring index significantly predicts operation failure. However, preoperative high baseline SpO2 predicts operation success significantly., Conclusion: The new Cahali lateral pharyngoplasty can be used as a stand-alone procedure in the absence of lateral wall collapse at the level of the hypopharynx (LH), high tongue base collapse (TH), laryngeal collapse (L1) or tongue palate interaction., (Copyright © 2020 Elsevier Inc. All rights reserved.)- Published
- 2020
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