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Your search keyword '"Elwes, R. D. C."' showing total 34 results
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34 results on '"Elwes, R. D. C."'

20. EEG correlated functional MRI and postoperative outcome in focal epilepsy

Author

Thornton, R., primary, Laufs, H., additional, Rodionov, R., additional, Cannadathu, S., additional, Carmichael, D. W., additional, Vulliemoz, S., additional, Salek-Haddadi, A., additional, McEvoy, A. W., additional, Smith, S. M., additional, Lhatoo, S., additional, Elwes, R. D. C., additional, Guye, M., additional, Walker, M. C., additional, Lemieux, L., additional, and Duncan, J. S., additional

Published
2010
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25. Interictal regional slow activity in temporal lobe epilepsy correlates with lateral temporal hypometabolism as imaged with 18FDG PET: neurophysiological and metabolic implications

Author

Koutroumanidis, M., primary, Binnie, C. D, additional, Elwes, R. D C, additional, Polkey, C. E, additional, Seed, P., additional, Alarcon, G., additional, Cox, T., additional, Barrington, S., additional, Marsden, P., additional, Maisey, M. N, additional, and Panayiotopoulos, C. P, additional

Published
1998
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30. Significance of interictal bilateral temporal hypometabolism in temporal lobe epilepsy

Author

Koutroumanidis, M., Hennessy, M. J., Seed, P. T., Elwes, R. D. C., Jarosz, J., Morris, R. G., Maisey, M. N., Binnie, C. D., and Polkey, C. E.

Abstract

To assess the clinical implications and the pathophysiologic determinants of interictal bitemporal hypometabolism (BTH) in temporal lobe epilepsy (TLE) not associated with bilateral MRI abnormalities or intracranial space-occupying lesions.

Published
2000

34. Imaging haemodynamic changes related to seizures: comparison of EEG-based general linear model, independent component analysis of fMRI and intracranial EEG.

Author

Thornton RC, Rodionov R, Laufs H, Vulliemoz S, Vaudano A, Carmichael D, Cannadathu S, Guye M, McEvoy A, Lhatoo S, Bartolomei F, Chauvel P, Diehl B, De Martino F, Elwes RD, Walker MC, Duncan JS, and Lemieux L

Subjects
Brain Mapping methods, Computer Simulation, Humans, Linear Models, Models, Neurological, Principal Component Analysis, Reproducibility of Results, Sensitivity and Specificity, Cerebrovascular Circulation, Electroencephalography methods, Image Interpretation, Computer-Assisted methods, Magnetic Resonance Imaging methods, Oxygen blood, Oxygen Consumption, Seizures physiopathology
Abstract

Background: Simultaneous EEG-fMRI can reveal haemodynamic changes associated with epileptic activity which may contribute to understanding seizure onset and propagation., Methods: Nine of 83 patients with focal epilepsy undergoing pre-surgical evaluation had seizures during EEG-fMRI and analysed using three approaches, two based on the general linear model (GLM) and one using independent component analysis (ICA): The results were compared with intracranial EEG., Results: The canonical GLM analysis revealed significant BOLD signal changes associated with seizures on EEG in 7/9 patients, concordant with the seizure onset zone in 4/7. The Fourier GLM analysis revealed changes in BOLD signal corresponding with the results of the canonical analysis in two patients. ICA revealed components spatially concordant with the seizure onset zone in all patients (8/9 confirmed by intracranial EEG)., Conclusion: Ictal EEG-fMRI visualises plausible seizure related haemodynamic changes. The GLM approach to analysing EEG-fMRI data reveals localised BOLD changes concordant with the ictal onset zone when scalp EEG reflects seizure onset. ICA provides additional information when scalp EEG does not accurately reflect seizures and may give insight into ictal haemodynamics., (Copyright 2010 Elsevier Inc. All rights reserved.)

Published
2010
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