Search

Your search keyword '"Elsner, Carlene W."' showing total 27 results
Start Over "Elsner, Carlene W."
27 results on '"Elsner, Carlene W."'

8. Multiple pregnancy rate and embryo number transferred during in vitro fertilization

Author

Elsner, Carlene W., Tucker, Michael J., Sweitzner, Cynthia L., Brockman, Wendy D.W., Morton, Paula C., Wright, Graham, and Toledo, Andrew A.

Subjects
Pregnancy, Multiple -- Risk factors, Fertilization in vitro, Human -- Health aspects, Health
Abstract

Women undergoing in vitro fertilization with multiple embryos implanted simultaneously may be at increased risk for multiple births. The multiple birth rate in 734 successfully implanted pregnancies was analyzed in reference to the number of embryos implanted. The multiple birth rate rose significantly with two or three implanted embryos but more than three embryos did not significantly increase the multiple birth risk. Of the 31.3% overall multiple births, 0.8% were quadruplets, 5.8% were triplets, and 24.7% were twins.

Published
1997

17. “The Best of Us”

Author

McDonough, Paul G., primary, Massey, Joe B., additional, Kort, Hilton I., additional, Tucker, Michael J., additional, and Elsner, Carlene W., additional

Published
1994
Full Text
View/download PDF

20. Cryopreservation of zygotes and early cleaved human embryos

Author

Cohen, Jacques, DeVane, Gary W., Elsner, Carlene W., Fehilly, Carole B., Kort, Hilton I., Massey, Joe B., and Turner, Thomas G.

Abstract

Zygotes and 2- to 5-cell human embryos were frozen in 1,2-propanediol and sucrose; results of the first 50cycles (45 patients) are presented. A total of 41 zygotes (17 attempts at thawing) were thawed, resulting in six singleton clinical pregnancies (15% per embryo; 35% per cycle), of which three delivered, one aborted, and two are ongoing. Fifty-seven cleaved embryos were thawed in 33 other cycles, resulting in four singleton and one twin pregnancy (11% per embryo; 15% per cycle), of which four delivered and one is ongoing. Depending on the cell stage, 61% to 81% of embryos survived cryostorage, but 2-cell embryos did not implant. One fifth of cryoinjury was due to the formation of cracks in the zona pellucida. The incidence of implantation was not enhanced when more than one freeze/thawed embryo was replaced, most pregnancies being obtained from single embryo replacements. At least 8% more births are expected in addition to conventional in vitro fertilization methods when the current policy of replacing three fresh embryos and freezing the remainder using this technique is applied. This method will result in two to four times more pregnancies per spare embryo, compared with other cryopreservation methods using older embryos.

Published
1988
Full Text
View/download PDF

23. Interrelationships of Circulating Maternal Steroid Concentrations in Third Trimester Pregnancies. III. Effect of Intravenous Cortisol Infusion on Maternal Concentrations of Estriol, 16α-Hydroxyprogesterone, 17α-Hydroxyprogesterone, Progesterone, 20α-Dihydroprogesterone, Δ5-Pregnenolone, Δ5-Pregnenolone Sulfate, Dehydroepiandrosterone Sulfate, and Cortisol

Author

ELSNER, CARLENE W., primary, BUSTER, JOHN E., additional, PRESTON, DALE L., additional, and KILLAM, ALLEN P., additional

Published
1979
Full Text
View/download PDF

26. Spermatozoal large RNA content is associated with semen characteristics, sociodemographic and lifestyle factors.

Author

Bianchi, Enrica, Boekelheide, Kim, Sigman, Mark, Braun, Joseph M., Eliot, Melissa, Hall, Susan J., Dere, Edward, and Hwang, Kathleen

Subjects
SEMEN, SEMEN analysis, SOCIODEMOGRAPHIC factors, NON-coding RNA, RNA, SPERMATOZOA, REPRODUCTIVE toxicology
Abstract

Semen analysis is one of the standard diagnostic tools currently used to assess male infertility and reproductive toxicity. However, semen analysis has a limited ability to separate fertile from infertile populations. Additional methods to detect impaired fertility are needed. The purpose of the present study was to evaluate how spermatozoal RNA content varies with sociodemographic and behavior/lifestyle factors, and to determine if spermatozoal large and small RNAs discriminate normal from abnormal spermatozoa. Semen specimens were collected from 133 men aged between 18 to 55 years undergoing semen analysis as part of couple infertility evaluation while 10 proven fertile donors were recruited as control group. Semen samples were classified as normal or abnormal according to World Health Organization (WHO) 2010 criteria. Sperm RNAs were extracted after somatic cells were lysed, and the association of large or small RNA content with semen quality and sociodemographic and behavioral/lifestyle factors was evaluated using a generalized additive model and one-way ANOVA. Inverse relationship was observed between large RNA content and sperm parameters such as sperm count, density and motility. Large RNA content per sperm was significantly increased in semen samples showing abnormal number of round cells. Furthermore, sperm motility was inversely associated with spermatozoal small RNA contents. Grouping donors by the number of semen abnormalities, we observed significant increased spermatozoal large and small RNA content in men with more than two semen abnormalities. Alcohol consumption was strongly associated with increased large RNA per sperm concentration after adjustment for age and BMI. Our study demonstrates a strong relationship between spermatozoal large RNA content and poor semen characteristics that may lead to a role in the assessment of male fertility, and may be used as an endpoint for reproductive toxicology risk assessment. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

27. How many IVF embryos to transfer?

Author

TUCKER, MICHAEL J., KORT, HILTON I., MASSEY, JOE B., ELSNER, CARLENE W., MITCHELL-LEEF, DOROTHY E., and TOLEDO, ANDREW A.

Subjects
*CRYOPRESERVATION of organs, tissues, etc., *EMBRYO transfer, *FERTILIZATION in vitro, *EVALUATION of medical care, *PREGNANCY
Published
1991
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results