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Background: One of the major health issues facing the world today is addiction. It is a rapidly developing health issue in Saudi Arabia. Given how intensely addictive methamphetamine is and how strongly its usage is linked to violent crimes and extremely aggressive conduct, methamphetamine addiction is one of the most hazardous health problems. There has been a concerning rise in the usage of crystal methamphetamine, often known as "Shabu," in the Saudi market in recent years. The aim of this work was to identify the type of aggressive behaviors and psychotic symptoms in patients' methamphetamine abuse and patients with polysubstance abuse without methamphetamine abuse in Emergency Department, Riyadh Hospitals. Methods: The study was conducted upon 100 drug abuse participants who attended Riyadh Saudi Arabia Emergency Department seeking for treatment of drug dependence. All patients were subjected to drug screening and assessment of delusions, mood disorders and Modified Overt Aggression Scale. Results: Verbal aggression, self-aggression and aggression against others were significantly higher in methamphetamine abusers' group than other polysubstance abusers group (p<0.05). Methamphetamine addicts exhibited higher rates of restlessness, the need for physical restraint, spouse betrayal of delusion, disorientation, and self-harm than other groups of polysubstance abusers (p<0.05). Conclusion: Methamphetamine abusers displayed significantly higher rates of aggressive behaviors and specific psychotic symptoms compared to other polysubstance abusers. [ABSTRACT FROM AUTHOR]

Background: Vaccination against COVID-19 during pregnancy is suggested to avoid pregnancy complications morbidity and bad delivery outcomes. However, the safety and efficacy of COVID-19 vaccinations during pregnancy is a specific issue impacting vaccination uptake by this susceptible group due to alterations in immune, respiratory, and cardiovascular physiology that occur during pregnancy. The purpose of this study was to examine the relationship between prenatal mother COVID-19 immunization, pregnancy course, and outcomes. Patients and Methods: A retroactive cohort analysis was conducted on all women who gave birth. Women having a previous COVID-19 diagnosis, numerous pregnancies, or an uncertain vaccination status were excluded. Pregnancy, neonatal problems, and delivery were compared with women who got 1 or 2 doses of a vaccine throughout pregnancy and women who did not get any vaccinations. Using multivariable models, the background characteristics were accounted for. Results: The pregnancy complications were higher in unvaccinated group than vaccinated group with no statistical significant difference except stillbirth that was present only in unvaccinated group (3%). Women who were vaccinated gave birth at a significantly later gestational age. No differences between the groups were detected in terms of postpartum and delivery factors. Women who received vaccination delivered at slightly higher birth weight. No differences were detected in terms of neonatal features and problems between the two groups. Conclusions: We concluded that COVID-19-vaccinated pregnant women experienced similar pregnancy outcomes as unvaccinated pregnant women. In some cases, vaccination proved to be better outcome than un-vaccination. [ABSTRACT FROM AUTHOR]