1. Sir Frederick Grant Banting.
- Author
-
Ellison, Jessica O.
- Abstract
Sir Frederick Grant Banting was born in Ontario, Canada, in 1891. In 1909, after his education in local primary and secondary schools, he entered the University of Toronto for a ministry degree. After one year, he switched to a medical degree. In 1918, Banting worked as an orthopedic surgeon. After two years, he taught anatomy and physiology at the University of Western Ontario. He also conducted medical research under the supervision of Frederick Robert Miller, a prominent neurophysiologist. Banting was dedicated to teaching. While researching the literature for an upcoming lecture on the pancreas, he became curious about previous work on diabetes and the pancreas. He read that if the pancreatic ducts were damaged but the islets of Langerhans remained intact, no diabetic symptoms developed. Researchers theorized that the islets of Langerhans released a hormone preventing diabetes. Extracting this compound, however, was a problem. Investigators speculated that other pancreatic secretions outside the islets of Langerhans destroyed the mystery hormone during extraction procedures. Researchers discovered that, with blockage of the pancreatic ducts, all regions in the pancreas atrophied except for the islets of Langerhans. Banting had a talent for synthesis. He read about many seemingly unrelated research discoveries about the pancreas and fit the pieces of the diabetes puzzle together. In October, 1920, he designed his famous experiment that increased the lifespan of diabetics. INSET: Sir Frederick Grant Banting.
- Published
- 1998