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1. N34 Transition of Inflammatory Bowel Disease patients from pediatric to adult Care: A single-center ten-years experience

Author

Onidi, F M, primary, Mocci, G, additional, Elisei, W, additional, Corpino, M, additional, Orru', G, additional, Marongiu, A, additional, Argiolas, G, additional, Runfola, M, additional, Locci, G, additional, Tamponi, E, additional, Zolfino, T, additional, Usai Satta, P, additional, Muscas, A, additional, Congia, M, additional, and Savasta, S, additional

Published
2024
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2. P544 Ustekinumab safety and effectiveness in ulcerative colitis patients: results from a large real-life study

Author

Mocci, G, primary, Scaldaferri, F, additional, Pugliese, D, additional, Savarino, E, additional, Bodini, G, additional, Cuomo, A, additional, Donnarumma, L, additional, Maconi, G, additional, Cataletti, G, additional, Rodino, S, additional, Sebkova, L, additional, Ferronato, A, additional, Gaiani, F, additional, Marzo, M, additional, Luppino, I, additional, Paese, P, additional, Elisei, W, additional, Monterubbianesi, R, additional, Faggiani, R, additional, Napolitano, D, additional, Grossi, L, additional, Serio, M, additional, Scarcelli, A, additional, Lorenzetti, R, additional, Allegretta, L, additional, Rocco, G, additional, Zampaletta, C, additional, Bolognini, L, additional, Meucci, C, additional, Colucci, R, additional, Tonti, P, additional, Della Valle, N, additional, Piga, R, additional, Forti, G, additional, Onidi, F M, additional, Usai Satta, P, additional, Picchio, M, additional, Papa, A, additional, and Tursi, A, additional

Published
2024
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4. P505 Real word long-term efficacy and safety of vedolizumab in managing ulcerative colitis versus crohn’s disease: results from “long vedo” italian multicenter study

Author

Mocci, G, primary, Maconi, G, additional, Onidi, F M, additional, Cataletti, G, additional, Elisei, W, additional, Scaldaferri, F, additional, Lorenzetti, R, additional, Pagnini, C, additional, Scarcelli, A, additional, Graziani, M G, additional, Di Paolo, M C, additional, Pranzo, G, additional, Luppino, I, additional, Monterubbianesi, R, additional, Faggiani, R, additional, Ferronato, A, additional, Savarino, E, additional, Pica, R, additional, Cocco, A, additional, Rodino, S, additional, Sebkova, L, additional, Zampaletta, C, additional, Gaiani, F, additional, Fanigliulo, L, additional, Allegretta, L, additional, Cuomo, A, additional, Donnarumma, L, additional, Della Valle, N, additional, Forti, G, additional, Antonelli, E, additional, Bassotti, G, additional, Iannelli, C, additional, Aragona, G, additional, Lauria, A, additional, Piergallini, S, additional, Colucci, R, additional, Binaghi, L, additional, Meucci, C, additional, Papa, A, additional, and Tursi, A, additional

Published
2023
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6. T.07.10 PERFORMANCE OF A MULTI-COMPOUNDS NUTRACEUTICAL FORMULATION IN PATIENTS WITH SYMPTOMATIC UNCOMPLICATED DIVERTICULAR DISEASE

Author

Gravina, A.G., primary, Brandimarte, G., additional, Frajese, G.V., additional, Bargiggia, S., additional, Castellani, D., additional, Cocco, A., additional, Colucci, R., additional, Evangelista, E., additional, Napoletano, D., additional, Nardi, E., additional, Maisto, T., additional, Morabito, A., additional, Pianese, G., additional, Romano, A., additional, Sacco, R., additional, Sinnona, N., additional, Sediari, L., additional, Tifi, L., additional, Davino, A., additional, Elisei, W., additional, and Tursi, A., additional

Published
2022
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9. Predictive value of the “DICA” classification on the outcome of diverticular disease of the colon: an international study: 3.14

Author

Tursi, A., Brandimarte, G., Di Mario, F., Annunziata, M. L., Bafutto, M., Bianco, M. A., Colucci, R., Conigliaro, R., Danese, S., De Bastiani, R., Elisei, W., Escalante, R., Faggiani, R., Ferrini, L., Forti, G., Latella, G., Graziani, M. G., Oliveira, E., Papa, A., Penna, A., Søreide, K., Spadaccini, A., Usai, P., Zampaletta, C., Cassieri, C., Desserud, K. F., Fiorella, S., Landi, R., Goni, E., Lai, M. A., Pigò, F., Scarpignato, C., Picchio, M., Scaccianoce, G., and Portincasa, P.

Published
2016

10. The DICA Endoscopic Classification for Diverticular Disease of the Colon Shows a Significant Interobserver Agreement among Community Endoscopists: an International Study

Author

Tursi A., Brandimarte G., Di Mario F., Lanas A., Scarpignato C., Bafutto M., Barbara G., Bassotti G., Binda G. A., Biondi A., Biondo S., Cassieri C., Crucitti A., Dumitrascu D. L., Elisei W., Escalante R., Herszenyi L., Kruis W., Kupcinskas J., Lahat A., Lecca P. G., Maconi G., Malfertheiner P., Mazzarri A., Mearin F., Milosavljevic T., Nardone G., de Oliveira E. C., Papa A., Papagrigoriadis S., Pera M., Persiani R., Picchio M., Regula J., Stimac D., Stollman N., Strate L. L., Walker M. M. D., Allegretta L., Altavilla N., Amaro P., Annunziata M. L., Barberio F., Basile G., Bedogni G., Belfiori V., Benvenuti S., Bertolami C., Bisello M., El Dammak M. B., Bozzi R., Buono M., Cambie G., Capezzuto E., Casamassima C., Chavoushian A., Ciofani R., Citarella C., Compare D., Cotruta B., D'amico F., Dulk M. D., Dyrda B. E., Festa V., Gallina S., Grasso R., Hanzel J., Taieb J. M., Lai M. A., Latella G., Lisi D., Lodi L., Marangi S., Mardegan A., Marlicz W., Maurano A., Milazzo G., Militaru V., Miraglia S., Monica F., Moskalev A., Natale A., Nicolas C., Pancetti A., Penna A., Pepe A. S., Pisano M., Pontone S., Prati M., Prisco A., Rando L., Hernandez E. R., Rosati O., Rossi G., Passoni G. R., Papa V., Nesme N. S., Schiffino L., Schillaci D., Selvaggi G., Taborchi F., Tornar A., Trebuna F., Triggiani C., Testai F. V., Vassallo R., Violi A., Tursi, A., Brandimarte, G., Di Mario, F., Lanas, A., Scarpignato, C., Bafutto, M., Barbara, G., Bassotti, G., Binda, G. A., Biondi, A., Biondo, S., Cassieri, C., Crucitti, A., Dumitrascu, D. L., Elisei, W., Escalante, R., Herszenyi, L., Kruis, W., Kupcinskas, J., Lahat, A., Lecca, P. G., Maconi, G., Malfertheiner, P., Mazzarri, A., Mearin, F., Milosavljevic, T., Nardone, G., de Oliveira, E. C., Papa, A., Papagrigoriadis, S., Pera, M., Persiani, R., Picchio, M., Regula, J., Stimac, D., Stollman, N., Strate, L. L., Walker, M. M. D., Allegretta, L., Altavilla, N., Amaro, P., Annunziata, M. L., Barberio, F., Basile, G., Bedogni, G., Belfiori, V., Benvenuti, S., Bertolami, C., Bisello, M., El Dammak, M. B., Bozzi, R., Buono, M., Cambie, G., Capezzuto, E., Casamassima, C., Chavoushian, A., Ciofani, R., Citarella, C., Compare, D., Cotruta, B., D'Amico, F., Dulk, M. D., Dyrda, B. E., Festa, V., Gallina, S., Grasso, R., Hanzel, J., Taieb, J. M., Lai, M. A., Latella, G., Lisi, D., Lodi, L., Marangi, S., Mardegan, A., Marlicz, W., Maurano, A., Milazzo, G., Militaru, V., Miraglia, S., Monica, F., Moskalev, A., Natale, A., Nicolas, C., Pancetti, A., Penna, A., Pepe, A. S., Pisano, M., Pontone, S., Prati, M., Prisco, A., Rando, L., Hernandez, E. R., Rosati, O., Rossi, G., Passoni, G. R., Papa, V., Nesme, N. S., Schiffino, L., Schillaci, D., Selvaggi, G., Taborchi, F., Tornar, A., Trebuna, F., Triggiani, C., Testai, F. V., Vassallo, R., Violi, A., Tursi A., Brandimarte G., Di Mario F., Lanas A., Scarpignato C., Bafutto M., Barbara G., Bassotti G., Binda G.A., Biondi A., Biondo S., Cassieri C., Crucitti A., Dumitrascu D.L., Elisei W., Escalante R., Herszenyi L., Kruis W., Kupcinskas J., Lahat A., Lecca P.G., Maconi G., Malfertheiner P., Mazzari A., Mearin F., Milosavljevic T., Nardone G., Chavez De Oliveira E., Papa A., Papagrigoriadis S., Pera M., Persiani R., Picchio M., Regula J., Stimac D., Stollman N., Strate L.L., and Walker M.M.

Subjects
BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences, Diverticular Disease, Endoscopic classification, Video Recording, Colonoscopy, Gastroenterology, Severity of Illness Index, endoscopic classification, Diverticulum, classification, complications, Diverticular diseases, Endoscopy, methods, Colonic Diseases, 0302 clinical medicine, Community Health Services, Community Health Service, Observer Variation, 0303 health sciences, medicine.diagnostic_test, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti, agreement − colonoscopy − community setting − diverticular disease of the colon− endoscopic classification, 3. Good health, Diverticulosis, Malalties del còlon, Diverticular disease of the colon, Diverticular disease, 616.344-007.64 [udc], Community setting, 030211 gastroenterology & hepatology, Human, medicine.medical_specialty, Scoring system, Colonic Disease, Settore MED/12 - GASTROENTEROLOGIA, Reproducibility of Result, agreement, colonoscopy, community setting, diverticular disease of the colon, Agreement, 03 medical and health sciences, Internal medicine, Severity of illness, medicine, Diverticulosis, Colonic, Humans, Colonic diseases, 030304 developmental biology, Diverticular Diseases, business.industry, Colonoscòpia, Reproducibility of Results, medicine.disease, Inter-rater reliability, business, Kappa
Abstract

Background and Aims: The Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification of diverticulosis and diverticular disease (DD) is currently available. It scores severity of the disease as DICA 1, DICA 2 and DICA 3. Our aim was to assess the agreement on this classification in an international endoscopists community setting. Methods: A total of 96 doctors (82.9% endoscopists) independently scored a set of DD endoscopic videos. The percentages of overall agreement on DICA score and a free-marginal multirater kappa (κ) coefficient were reported as statistical measures of interrater agreement. Results: Overall agreement in using DICA was 91.8% with a free-marginal kappa of 88% (95% CI 80-95). The overall agreement levels were: DICA 1, 85.2%; DICA 2, 96.5%; DICA 3, 99.5%. The free marginal κ was: DICA 1 = 0.753, DICA 2 = 0.958, DICA 3 = 0.919. The agreement about the main endoscopic items was 83.4% (k 67%) for diverticular extension, 62.6% (k 65%) for number of diverticula for each district, 86.8% (k 82%) for presence of inflammation, and 98.5 (k 98%) for presence of complications. Conclusions: The overall interrater agreement in this study ranges from good to very good. DICA score is a simple and reproducible endoscopic scoring system for diverticulosis and DD.

Published
2019

11. Predictive value of the ‘DICA’ classification on the outcome of diverticular disease of the colon: 2.14

Author

Tursi, A., Brandimarte, G., Di Mario, F., Annunziata, M. L., Bianco, M. A., Conigliaro, R., Elisei, W., Faggiani, R., Forti, G., Lecca, P. G., Penna, A., Spadaccini, A., Zampaletta, C., Colucci, R., De Bastiani, R., Di Cesare, L., Di Fonzo, M., Goni, E., Ferrini, L., Graziani, M. G., Latella, G., Pigò, F., Rotondano, G., Schiaccianoce, G., Picchio, M., Scarpignato, C., and Portincasa, P.

Published
2015

12. P583 Real-life efficacy and safety of Ustekinumab as second- or third-line therapy in Crohn’s disease: results from a large Italian cohort study

Author

Mocci, G, primary, Cuomo, A, additional, Allegretta, L, additional, Aragona, G, additional, Colucci, R, additional, Della Valle, N, additional, Ferronato, A, additional, Forti, G, additional, Gaiani, F, additional, Graziani, M G, additional, Lorenzetti, R, additional, Luzza, F, additional, Penna, A, additional, Pica, R, additional, Piergallini, S, additional, Rodinò, S, additional, Scarcelli, A, additional, Zampaletta, C, additional, Cicerone, C, additional, Cocco, A, additional, De Angelis, G, additional, Donnarumma, L, additional, Pranzo, G, additional, Franceschi, M, additional, Gallina, S, additional, Grasso, G, additional, Larussa, T, additional, Luppino, I, additional, Faggiani, R, additional, Fanigliulo, L, additional, Pagnini, C, additional, Perazzo, P, additional, Sacco, R, additional, Sebkova, L, additional, Serio, M E, additional, De Monti, A, additional, Picchio, M, additional, Elisei, W, additional, Maconi, G, additional, and Tursi, A, additional

Published
2021
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17. The prevalence of celiac disease and the appropriateness of the diagnosis in family medicine setting could be lower than expected.

Author

GIORGETTI, G. M., DE VITIS, I., FABIOCCHI, F., CHIRIATTI, A., NATI, G., CANTARINI, R., FIORILLO, A., SCARABOTTI, A., BATTIMELLI, C., ELISEI, W., and TURSI, A.

Abstract

OBJECTIVE: To assess the prevalence of celiac disease (CD) and the appropriateness of this diagnosis in the family medicine setting in Italy. PATIENTS AND METHODS: The electronic databases of 16 general practitioners working in Rome (Italy) were analyzed. The prevalence of CD according to the Italian pathology identification code issued by the Italian National Health System was assessed. In addition, patients registered as having celiac disease without being assigned a pathology identification code were interviewed. RESULTS: Overall, a population of 22,064 patients was analyzed. 91 patients had a diagnosis of CD (0.41%), 60 of whom had a pathology identification code (0.27%), and 31 did not (0.14%). 29 of these patients were interviewed, 16 (17.58% of the CD recorded patients) of whom reported being on a gluten-free or gluten restricted diet, with reported improvement in their clinical symptoms. Half of them further stated that they would not agree to resume a restriction free diet in order to make a definitive CD diagnosis, due to the risk of symptom recurrence. CONCLUSIONS: In a family medicine setting, the prevalence of CD seems to be lower than expected, and one third of patients diagnosed with CD do not fulfill all diagnostic criteria. Any effort to improve the diagnostic work-up for CD should also be made in this setting. [ABSTRACT FROM AUTHOR]

Published
2022

18. Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease – a double-blind, randomised, placebo-controlled study

Author

Tursi, A., Brandimarte, G., Elisei, W., Picchio, M., Forti, G., Pianese, G., Rodino, S., DʼAmico, T., Sacca, N., Portincasa, P., Capezzuto, E., Lattanzio, R., Spadaccini, A., Fiorella, S., Polimeni, F., Polimeni, N., Stoppino, V., Stoppino, G., Giorgetti, G. M., Aiello, F., and Danese, S.

Published
2013
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24. OC.08.3 THE “DICA” ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE OF THE COLON SHOWS A SIGNIFICANT INTEROBSERVER AGREEMENT AMONG COMMUNITY ENDOSCOPISTS: AN INTERNATIONAL STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Lanas, A., additional, Scarpignato, C., additional, Bafutto, M., additional, Barbara, G., additional, Bassotti, G., additional, Binda, G.A., additional, Biondi, A., additional, Biondo, S., additional, Cambiè, G., additional, Cassieri, C., additional, Crucitti, A., additional, Dumitrascu, D., additional, Elisei, W., additional, Escalante, R., additional, Herszènyi, L., additional, Kruis, W., additional, Kupcinskas, J., additional, Lahat, A., additional, Lecca, P.G., additional, Maconi, G., additional, Malfertheiner, P., additional, Mazzari, A., additional, Mearìn, F., additional, Milosavljevic, T., additional, Nardone, G., additional, Chavez De Oliveira, E., additional, Papa, A., additional, Papagrigoriadis, S., additional, Pera, M., additional, Persiani, R., additional, Picchio, M., additional, Regula, J., additional, Štimac, D., additional, Stollman, N., additional, Strate, L., additional, Violi, A., additional, and Walker, M., additional

Published
2020
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25. T04.02.19 CLINICAL AND EPIDEMIOLOGICAL FEATURES OF ULCERATIVE COLITIS PATIENTS IN SARDINIA, ITALY – RESULTS FROM A MULTICENTER STUDY

Author

Mocci, G., primary, Demurtas, M., additional, Onidi, F.M., additional, Picchio, M., additional, Elisei, W., additional, Manca, R., additional, Miculan, F., additional, Dore, M.P., additional, Quarta Colosso, B., additional, Cicu, A., additional, Cugia, L., additional, Pisanu, R., additional, Carta, M., additional, Binaghi, L., additional, Dore, M.F., additional, Usai, P., additional, Chicco, F., additional, Lai, M.A., additional, Magrì, S., additional, Mais, C., additional, Porcedda, M.L., additional, Argiolas, M., additional, Cabras, F., additional, and Armuzzi, A., additional

Published
2020
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26. T04.01.15 QUALITY OF LIFE AND PERCEPTION OF CARE FOR ULCERATIVE COLITIS PATIENTS IN SARDINIA: RESULTS OF A MULTICENTER OBSERVATIONAL STUDY

Author

Mocci, G., primary, Onidi, F.M., additional, Demurtas, M., additional, Picchio, M., additional, Elisei, W., additional, Manca, R., additional, Miculan, F., additional, Mais, C., additional, Dore, M.P., additional, Quarta Colosso, B., additional, Cicu, A., additional, Cugia, L., additional, Pisanu, R., additional, Carta, M., additional, Binaghi, L., additional, Dore, M.F., additional, Usai, P., additional, Lai, M.A., additional, Chicco, F., additional, Magrì, S., additional, Porcedda, M.L., additional, Argiolas, M., additional, Cabras, F., additional, and Armuzzi, A., additional

Published
2020
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29. P787 Clinical and epidemiological features of ulcerative colitis patients in Sardinia, Italy: Results from a multicentre study

Author

Mocci, G, primary, Demurtas, M, additional, Onidi, F M, additional, Picchio, M, additional, Elisei, W, additional, Manca, R, additional, Miculan, F, additional, Mais, C, additional, Usai, P, additional, Chicco, F, additional, Lai, M A, additional, Magrì, S, additional, Binaghi, L, additional, Dore, M F, additional, Dore, M P, additional, Colosso, B Q, additional, Cugia, L, additional, Carta, M, additional, Pisanu, R, additional, Marzo, M, additional, Porcedda, M L, additional, Argiolas, M, additional, Cabras, F, additional, and Armuzzi, A, additional

Published
2020
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32. International consensus on diverticulosis and diverticular disease. Statements from the 3rd international symposium on diverticular disease

Author

Tursi, A., Brandimarte, G., Di Mario, F., Lanas, A., Scarpignato, C., Bafutto, M., Barbara, G., Bassotti, G., Binda, G. A., Biondi, Alberto, Biondo, S., Cambie, G., Cassieri, C., Crucitti, Antonio, Dumitrascu, D. L., Elisei, W., Escalante, R., Herszenyi, L., Kruis, W., Kupcinskas, J., Lahat, A., Lecca, P. G., Maconi, G., Malfertheiner, P., Mazzari, A., Mearin, F., Milosavljevic, T., Nardone, G., de Oliveira, E. C., Papa, Alfredo, Papagrigoriadis, S., Pera, M., Persiani, Roberto, Picchio, M., Regula, J., Stimac, D., Stollman, N., Strate, L. L., Violi, A., Walker, M. M. D., Biondi A. (ORCID:0000-0002-2470-7858), Crucitti A. (ORCID:0000-0003-3496-4185), Persiani R. (ORCID:0000-0002-1537-5097), Tursi, A., Brandimarte, G., Di Mario, F., Lanas, A., Scarpignato, C., Bafutto, M., Barbara, G., Bassotti, G., Binda, G. A., Biondi, Alberto, Biondo, S., Cambie, G., Cassieri, C., Crucitti, Antonio, Dumitrascu, D. L., Elisei, W., Escalante, R., Herszenyi, L., Kruis, W., Kupcinskas, J., Lahat, A., Lecca, P. G., Maconi, G., Malfertheiner, P., Mazzari, A., Mearin, F., Milosavljevic, T., Nardone, G., de Oliveira, E. C., Papa, Alfredo, Papagrigoriadis, S., Pera, M., Persiani, Roberto, Picchio, M., Regula, J., Stimac, D., Stollman, N., Strate, L. L., Violi, A., Walker, M. M. D., Biondi A. (ORCID:0000-0002-2470-7858), Crucitti A. (ORCID:0000-0003-3496-4185), and Persiani R. (ORCID:0000-0002-1537-5097)

Abstract

The statements produced by the Chairmen and Speakers of the 3rd International Symposium on Diverticular Disease, held in Madrid on April 11th-13th 2019, are reported. Topics such as current and evolving concepts on the pathogenesis, the course of the disease, the news in diagnosing, hot topics in medical and surgical treatments, and finally, critical issues on the disease were reviewed by the Chairmen who proposed 39 statements graded according to level of evidence and strength of recommendation. Each topic was explored focusing on the more relevant clinical questions. The vote was conducted on a 6-point scale and consensus was defined a priori as 67% agreement of the participants. The voting group consisted of 124 physicians from 18 countries, and agreement with all statements was provided. Comments were added explaining some controversial areas.

Published
2019

35. P.02.12 PREDICTIVE VALUE OF THE “DICA” ENDOSCOPIC CLASSIFICATION ON THE OUTCOME OF DIVERTICULAR DISEASE OF THE COLON: A 1-YEAR ANALYSIS FROM THE INTERNATIONAL, MULTICENTER, PROSPECTIVE STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Elisei, W., additional, Picchio, M., additional, Allegretta, L., additional, Annunziata, M.L., additional, Astegiano, M., additional, Bafutto, M., additional, Baldi, F., additional, Bassotti, G., additional, Bianco, M.A., additional, Colucci, R., additional, Conigliaro, R., additional, Danese, S., additional, Dumitrascu, D.L., additional, Escalante, R., additional, Faggiani, R., additional, Fiorella, S., additional, Forti, G., additional, Franceschi, M., additional, Giorgetti, G., additional, Grad, S., additional, Graziani, M.G., additional, Lai, M.A., additional, Lammert, F., additional, Latella, G., additional, Lisi, D., additional, Maconi, G., additional, Murphy, M.M., additional, Nardone, G., additional, De Oliveira, L. Camara, additional, De Oliveira, E. Chaves, additional, Papa, A., additional, Papagrigoriadis, S., additional, Penna, A., additional, Pietrzak, A., additional, Pontone, S., additional, Portincasa, P., additional, Poskus, T., additional, Pranzo, G., additional, Reichert, M., additional, Rizzo, G.L., additional, Rodinò, S., additional, Regula, J., additional, Scaccianoce, G., additional, Scaldaferri, F., additional, Schiffino, L., additional, Stundiene, I., additional, Vassallo, R., additional, Walker, M., additional, Zampaletta, C., additional, and Zullo, A., additional

Published
2019
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39. OC.03.3 THE “DICA” ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE OF THE COLON SHOWS A SIGNIFICANT INTEROBSERVER AGREEMENT AMONG COMMUNITY ENDOSCOPISTS

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Nardone, G., additional, Scarpignato, C., additional, Picchio, M., additional, Elisei, W., additional, Allegretta, L., additional, Annunziata, M.L., additional, Astegiano, M., additional, Baldi, F., additional, Bassotti, G., additional, Bianco, M.A., additional, Cambiè, G., additional, Capezzuto, E., additional, Caroli, A., additional, Cassieri, C., additional, Cicu, A.S., additional, Ciliberto, E., additional, Colucci, R., additional, Conigliaro, R., additional, Damiani, A., additional, De Colibus, P., additional, De Medici, A., additional, De Pretis, G., additional, Favero, G. Del, additional, Valle, N. Della, additional, Di Cesare, L., additional, Faggiani, R., additional, Febbraro, S., additional, Ferrini, L., additional, Fiorella, S., additional, Forti, G., additional, Franceschi, M., additional, Frunzio, A., additional, Germanà, B., additional, Giorgetti, G., additional, Giovannone, M., additional, Graziani, M.G., additional, Lai, M.A., additional, Latella, G., additional, Lisi, D., additional, Lopetuso, L.R., additional, Maconi, G., additional, Mandelli, E.D., additional, Marmo, R., additional, Maurano, A., additional, Pallotta, L., additional, Papa, A., additional, Parmeggiani, F., additional, Penna, A., additional, Pigò, F., additional, Pontone, S., additional, Pranzo, G., additional, Ricciardelli, C., additional, Rizzo, G.L., additional, Rodinò, S., additional, Savarino, E., additional, Scaccianoce, G., additional, Scaldaferri, F., additional, Schiffino, L., additional, Semeraro, C., additional, Stroppa, I., additional, Urgesi, R., additional, Vassallo, R., additional, Violi, A., additional, Zampaletta, C., additional, Lecca, P.G., additional, Zilli, M., additional, and Zullo, A., additional

Published
2019
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40. Effectiveness and Safety of Pylera® in Patients Infected by Helicobacter Pylori: A Multicenter, Retrospective, Real Life Study

Author

Tursi, A., Franceschi, M., Allegretta, L., Savarino, E., De Bastiani, R., Elisei, W., Baldassarre, G., Ferronato, A., Scida, S., Miraglia, C., Penna, A., Licci, C., Rizzo, G. L., Pranzo, G., Cassieri, C., Brandimarte, G., Picchio, M., and Di Mario, F.

Subjects
Male, Helicobacter pylori, Antibiotics, Bismuth-containing therapy, Safety, Treatment, Anti-Bacterial Agents, Bismuth, Demography, Drug Therapy, Combination, Endoscopy, Female, Helicobacter Infections, Humans, Metronidazole, Middle Aged, Organometallic Compounds, Retrospective Studies, Tetracycline, Treatment Outcome, Drug Therapy, Combination
Abstract

Our aims were to assess the real life effectiveness and safety of the new bismuth-containing quadruple therapy in a large population of patients infected by Helicobacter pylori.Consecutive dyspeptic H. pylori-positive patients were enrolled, both naïve for treatment and already unsuccessfully treated. Patients were treated with Pylera® 3 capsules 4 times/daily plus omeprazole 20 mg or esomeprazole 40 mg 2 times/daily for 10 days. Eradication was confirmed using a urea-breath test (at least 30 days after the end of the treatment). Efficacy and safety were assessed.A total of 349 patients were treated. H. pylori eradication was achieved in 316 (90.5%, 95% CIs 80.8-1.0) patients in the intention-to-treat population, and in 93.5% (95% CIs 83.5-1.0) in the per-protocol population. No difference in the eradication rate was found between naïve and previously treated patients (91.3 vs. 90.0%, p = 0.901). Adverse events occurred in 55 patients (15.8%, 95% CIs 11.9-20.1). Five patients discontinued treatment: 2 patients suffered from severe abdominal pain, one patient from headache, one patient from diarrhea, and one patient from diffuse urticarial rush.Pylera® achieved a remarkable eradication rate in real life both as first treatment and as a rescue therapy, with a good safety profile.

Published
2017

43. Predictive value of the Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification on the outcome of diverticular disease of the colon: An international study

Author

Tursi A, Brandimarte G, Di Mario F, Annunziata ML, Bafutto M, Bianco MA, Colucci R, Conigliaro R, Danese S, De Bastiani R, Elisei W, Escalante R, Faggiani R, Ferrini L, Forti G, Latella G, Graziani MG, Oliveira EC, Papa A, Penna A, Portincasa P, Soreide K, Spadaccini A, Usai P, Bonovas S, Scarpignato C, Picchio M, Di Cesare L, Lecca PG, Zampaletta C, Cassieri C, Damiani A, Desserud KF, Fiorella S, Landi R, Goni E, Lai MA, Pigo F, Rotondano G, Schiaccianoce G, Tursi, A, Brandimarte, G, Di Mario, F, Annunziata, Ml, Bafutto, M, Bianco, Ma, Colucci, R, Conigliaro, R, Danese, S, De Bastiani, R, Elisei, W, Escalante, R, Faggiani, R, Ferrini, L, Forti, G, Latella, G, Graziani, Mg, Oliveira, Ec, Papa, A, Penna, A, Portincasa, P, Soreide, K, Spadaccini, A, Usai, P, Bonovas, S, Scarpignato, C, Picchio, M, Di Cesare, L, Lecca, Pg, Zampaletta, C, Cassieri, C, Damiani, A, Desserud, Kf, Fiorella, S, Landi, R, Goni, E, Lai, Ma, Pigo, F, Rotondano, G, and Schiaccianoce, G

Subjects
medicine.medical_specialty, Settore MED/12 - GASTROENTEROLOGIA, colon, Colonoscopy, diverticular disease, endoscopic classification, outcome, surgery, Oncology, Gastroenterology, Inflammation, digestive system, 03 medical and health sciences, 0302 clinical medicine, medicine, Special section on Fibrosis in Crohn's disease and inflammatory bowel disorders, medicine.diagnostic_test, business.industry, General surgery, digestive, oral, and skin physiology, medicine.disease, Predictive value, digestive system diseases, Surgery, Diverticulosis, surgical procedures, operative, 030220 oncology & carcinogenesis, Diverticular disease, 030211 gastroenterology & hepatology, medicine.symptom, Complication, business
Abstract

Background Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification has been recently developed for patients suffering from diverticulosis and diverticular disease. Aims We assessed retrospectively the predictive value of DICA in patients for whom endoscopic data and clinical follow-up were available. Methods For each patient, we recorded: age, severity of DICA, presence of abdominal pain, C-reactive protein and faecal calprotectin test (if available) at the time of diagnosis months of follow-up therapy taken during the follow-up to maintain remission (if any) occurrence/recurrence of diverticulitis need of surgery. Results We enrolled 1651 patients (793M, 858F, mean age 66.611.1 years): 939 (56.9%) patients were classified as DICA 1, 501 (30.3%) patients as DICA 2 and 211 (12.8%) patients as DICA 3. The median follow-up was 24 (9-38) months. Acute diverticulitis (AD) occurred/recurred in 263 (15.9%) patients surgery was necessary in 57 (21.7%) cases. DICA was the only factor significantly associated to the occurrence/recurrence of diverticulitis and surgery either at univariate ((2)=405.029 p

Published
2016

45. P.06.14 EFFECTIVENESS AND SAFETY OF PYLERA ® IN PATIENTS INFECTED BY HELICOBACTER PYLORI: A LARGE, PROSPECTIVE, REAL LIFE STUDY

Author

Tursi, A., primary, Franceschi, M., additional, Allegretta, L., additional, Savarino, E., additional, De Bastiani, R., additional, Elisei, W., additional, Baldassarre, G., additional, Ferronato, A., additional, Penna, A., additional, Licci, C., additional, Rizzo, G.L., additional, Pranzo, G., additional, Cassieri, C., additional, Brandimarte, G., additional, Picchio, M., additional, Scida, S., additional, Miraglia, C., additional, and Di Mario, F., additional

Published
2018
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47. P.05.7 EPIDEMIOLOGY OF DIVERTICULAR DISEASE OF THE COLON: A PRELIMINARY ANALYSIS FROM THE INTERNATIONAL “DICA” PROSPECTIVE STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Elisei, W., additional, Picchio, M., additional, Annunziata, M.L., additional, Bafutto, M., additional, Bianco, M.A., additional, Costin, S., additional, Danese, S., additional, Dumitrascu, D., additional, Escalante, R., additional, Faggiani, R., additional, Franceschi, M., additional, Graziani, M.G., additional, Lammert, F., additional, Latella, G., additional, Maconi, G., additional, Murphy, M.M., additional, Nardone, G., additional, Oliveira, L., additional, Oliveira, E. Chaves, additional, Papa, P., additional, Papagrigoriadis, S., additional, Penna, A., additional, Pietrzak, A., additional, Reichert, M., additional, Rodinò, S., additional, Poskus, T., additional, Regula, J., additional, Scaldaferri, F., additional, Stundiene, L., additional, Vassallo, R., additional, and Marjorie, W., additional

Published
2018
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48. P.05.9 SURGERY FOR NON-INVASIVE COLORECTAL NEOPLASMS IN A POPULATION-BASED SCREENING PROGRAM

Author

Iacopini, F., primary, Hassan, C., additional, Mattei, E., additional, Ceci, V., additional, Frontespezi, S., additional, Brighi, S., additional, Fedeli, P., additional, Angeletti, S., additional, Fanello, G., additional, D'Ovidio, V., additional, De Palo, M.G., additional, Cocco, A., additional, Forte, A., additional, Forti, G., additional, Elisei, W., additional, Grossi, C., additional, Altavilla, N., additional, Dimito, G., additional, Occhigrossi, G., additional, Di Giulio, E., additional, Bazuro, E., additional, Ballanti, R., additional, Faggiani, R., additional, Scozzarro, A., additional, Capezzuto, E., additional, Baldi, F., additional, Baiocchi, D., additional, and Barca, A., additional

Published
2018
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