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Extramammary Paget disease is a rare condition that most commonly affects the anogenital region in the elderly. The treatment of choice has been surgical excision of the affected area with adequate depth and lateral margins, criteria that cannot always be fulfilled, especially when the vulva, anal canal, or penis are involved. More recently radiotherapy has been suggested as a suitable treatment when surgical excision or other modalities are not appropriate. We report a case of anogenital extramammary Paget disease and the clinical response to treatment with radiotherapy. The aim of this article is to review relevant aspects of radiotherapy as a first-choice curative treatment in specific situations of anogenital extramammary Paget disease in situ.

Cobb syndrome is a rare non-inherited neurocutaneous disease, in which there are metameric cutaneous and spinal vascular malformations of the trunk. In cases of segmentally distributed multiple cutaneous vascular lesions, early diagnostic imaging of the spinal cord allows prompt intervention in order to reduce permanent neurological sequelae. We report case of Cobb syndrome in a 12-year-old boy and present a systematic review of the literature.

Auteur(s) : Joaquin SOLA-ORTIGOSA 38725jso@comb.cat, Elisabet DILME-CARRERAS, Maribel IGLESIAS-SANCO, Gemma MARQUEZ-BALBAS, Manuel SANCHEZ-REGANA, Pau UMBERT-MILLET Service of Dermatology, Hospital Universitari Sagrat Cor, C/Paris 83-85, E-08029 Barcelona, Spain Carpal tunnel syndrome (CTS) is the leading cause of acroparaesthesia in upper limbs and the most common entrapment neuropathy [1-4]. Clinically, CTS is characterised by the insidious onset of neurological manifestations, predominantly [...]

Auteur(s) : Gemma Marquez Balbas, Angeles Sola Casas, Maribel Iglesias Sancho, Manuel Sanchez-Regana, Loida Galvany Rossell, Elisabet Dilme Carreras, Joaquim Sola Ortigosa, Pablo Umbert Millet Dept of Dermatology, Dermatology Univesitary Hospital Sagrat cor, Viladomat street 288, 08029 Barcelona, Spain Mycosis fungoides palmaris en plantaris (MFPP) is a variant of mycosis fungoides (MF) that presents primarily on the palms and soles [1], and it has been infrequently described. Herein [...]