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40 results on '"Elhmidi, Yacine"'

1. Partial versus Complete Sternotomy for Aortic Valve Replacement—Multicenter Study

Author

Goebel, Nora, additional, Stankowski, Tomasz, additional, Pollari, Francesco, additional, Hassan, Kambiz, additional, Jueckstock, Helena, additional, Schubel, Jens, additional, Sellin, Christian, additional, Zielezinski, Thorsten, additional, Elhmidi, Yacine, additional, Sack, Falk-Udo, additional, Feyrer, Richard, additional, Doerge, Hilmar, additional, Hausmann, Harald, additional, Massoudy, Parwis, additional, Schmoeckel, Michael, additional, Hakmi, Samer, additional, Fischlein, Theodor, additional, Fritzsche, Dirk, additional, and Franke, Ulrich F. W., additional

Published
2024
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6. Impact of Non-Valvular Non-Coronary Concomitant Procedures on Outcomes of Surgical Aortic Valve Replacement in Intermediate Risk Patients

Author

Mourad, Fanar, primary, Haddad, Ali, additional, Nowak, Janine, additional, Elbarraki, Mohamed, additional, Elhmidi, Yacine, additional, Jasarevic, Marinela, additional, Marx, Philipp, additional, Demircioglu, Ender, additional, Wendt, Daniel, additional, Thielmann, Matthias, additional, Schmack, Bastian, additional, Ruhparwar, Arjang, additional, and Shehada, Sharaf-Eldin, additional

Published
2021
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14. The Clinical Impact of Psoas Muscle Cross-Sectional Area on Medium-Term Mortality After Transcatheter Aortic Valve Implantation

Author

Michel, Jonathan, primary, Pellegrini, Costanza, additional, Rheude, Tobias, additional, von Scheidt, Moritz, additional, Trenkwalder, Teresa, additional, Elhmidi, Yacine, additional, Mayr, N. Patrick, additional, Brecker, Stephen, additional, Kasel, A. Markus, additional, Kastrati, Adnan, additional, Schunkert, Heribert, additional, Husser, Oliver, additional, Bleiziffer, Sabine, additional, and Hengstenberg, Christian, additional

Published
2020
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18. Transcatheter versus Surgical Aortic Valve Replacement after Previous Cardiac Surgery: A Systematic Review and Meta-Analysis

Author

Shehada, Sharaf-Eldin, primary, Elhmidi, Yacine, additional, Öztürk, Öznur, additional, Kasel, Markus, additional, Frangieh, Antonio H., additional, Mourad, Fanar, additional, Benedik, Jaroslav, additional, El Bahi, Jaafar, additional, El Gabry, Mohamed, additional, Thielmann, Matthias, additional, Jakob, Heinz, additional, and Wendt, Daniel, additional

Published
2018
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23. Outcomes of Redo Transcatheter Aortic Valve Replacement for the Treatment of Postprocedural and Late Occurrence of Paravalvular Regurgitation and Transcatheter Valve Failure

Author

Barbanti, Marco, primary, Webb, John G., additional, Tamburino, Claudia, additional, Van Mieghem, Nicolas M., additional, Makkar, Raj R., additional, Piazza, Nicolò, additional, Latib, Azeem, additional, Sinning, Jan-Malte, additional, Won-Keun, Kim, additional, Bleiziffer, Sabine, additional, Bedogni, Francesco, additional, Kapadia, Samir, additional, Tchetche, Didier, additional, Rodés-Cabau, Josep, additional, Fiorina, Claudia, additional, Nombela-Franco, Luis, additional, De Marco, Federico, additional, de Jaegere, Peter P., additional, Chakravarty, Tarun, additional, Vaquerizo, Beatriz, additional, Colombo, Antonio, additional, Svensson, Lars, additional, Lange, Rüdiger, additional, Nickenig, Georg, additional, Möllmann, Helge, additional, Walther, Thomas, additional, Della Rosa, Francesco, additional, Elhmidi, Yacine, additional, Dvir, Danny, additional, Brambilla, Nedy, additional, Immè, Sebastiano, additional, Sgroi, Carmelo, additional, Gulino, Simona, additional, Todaro, Denise, additional, Pilato, Gerlando, additional, Petronio, Anna Sonia, additional, and Tamburino, Corrado, additional

Published
2016
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28. Health-Related Quality of Life and Functional Outcome in Cardiac Surgical Patients Aged 80 Years and Older: A Prospective Single Center Study

Author

Deutsch, Marcus-André, primary, Krane, Markus, additional, Schneider, Lisa, additional, Wottke, Michael, additional, Kornek, Matthias, additional, Elhmidi, Yacine, additional, Badiu, Catalin Constantin, additional, Bleiziffer, Sabine, additional, Voss, Bernhard, additional, and Lange, Rüdiger, additional

Published
2013
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32. DIFFERENCES IN CLINICAL OUTCOMES BASED ON ADHERENCE TO VALVE SIZING CRITERIA USING 2D ECHOCARDIOGRAPHY OR 3D COMPUTED TOMOGRAPHY IN PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE IMPLANTATION

Author

Piazza, Nicolo, primary, Hill, Alexander, additional, Brockmann, Gernot, additional, Opitz, Anke, additional, Mazzitelli, Domenico, additional, Elhmidi, Yacine, additional, Ruge, Hendrik, additional, Bleiziffer, Sabine, additional, and Lange, Rudiger, additional

Published
2012
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33. Improvements in Transcatheter Aortic Valve Implantation Outcomes in Lower Surgical Risk Patients

Author

Lange, Ruediger, primary, Bleiziffer, Sabine, additional, Mazzitelli, Domenico, additional, Elhmidi, Yacine, additional, Opitz, Anke, additional, Krane, Marcus, additional, Deutsch, Marcus-Andre, additional, Ruge, Hendrik, additional, Brockmann, Gernot, additional, Voss, Bernhard, additional, Schreiber, Christian, additional, Tassani, Peter, additional, and Piazza, Nicolo, additional

Published
2012
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34. Prognostic Value of High-Dose Dobutamine Stress Magnetic Resonance Imaging in 1,493 Consecutive Patients

Author

Korosoglou, Grigorios, primary, Elhmidi, Yacine, additional, Steen, Henning, additional, Schellberg, Dieter, additional, Riedle, Nina, additional, Ahrens, Johannes, additional, Lehrke, Stephanie, additional, Merten, Constanze, additional, Lossnitzer, Dirk, additional, Radeleff, Jannis, additional, Zugck, Christian, additional, Giannitsis, Evangelos, additional, and Katus, Hugo A., additional

Published
2010
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35. Improvements in Transcatheter Aortic Valve Implantation Outcomes in Lower Surgical Risk Patients A Glimpse Into the Future

Author

Lange, Ruediger, Bleiziffer, Sabine, Mazzitelli, Domenico, Elhmidi, Yacine, Opitz, Anke, Krane, Marcus, Deutsch, Marcus-Andre, Ruge, Hendrik, Brockmann, Gernot, Voss, Bernhard, Schreiber, Christian, Tassani, Peter, and Piazza, Nicolo

Subjects
transcatheter aortic, valve implantation, aortic stenosis
Abstract

ObjectivesThe purpose of this study was to investigate the evolution of patient selection criteria for transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes.BackgroundAnecdotal evidence suggests that patient selection for TAVI is shifting toward lower surgical risk patients. The extent of this shift and its impact on clinical outcomes, however, are currently unknown.MethodsWe conducted a single-center study that subcategorized TAVI patients into quartiles (Q1 to Q4) defined by enrollment date. These subgroups were subsequently examined for differences in baseline characteristics and 30-day and 6-month mortality rate. The relationship between quartiles and mortality rate was examined using unadjusted and adjusted (for baseline characteristics) Cox proportional hazard models.ResultsEach quartile included 105 patients (n = 420). Compared with Q4 patients, Q1 patients had higher logistic EuroSCORES (25.4 ± 16.1% vs. 17.8 ± 12.0%, p < 0.001), higher Society of Thoracic Surgeons scores (7.1 ± 5.5% vs. 4.8 ± 2.6%, p > 0.001), and higher median N-terminal pro–B-type natriuretic peptide levels (3,495 vs. 1,730 ng/dl, p < 0.046). From Q1 to Q4, the crude 30-day and 6-month mortality rate decreased significantly from 11.4% to 3.8% (unadjusted hazard ratio [HR]: 0.33; 95% confidence interval [CI]: 0.11 to 1.01; p = 0.053) and from 23.5% to 12.4% (unadjusted HR: 0.49; 95 CI: 0.25 to 0.95; p = 0.07), respectively. After adjustment for baseline characteristics, there were no significant differences between Q1 and Q4 in 30-day mortality rate (adjusted HR ratio: 0.29; 95% CI: 0.08 to 1.08; p = 0.07) and 6-month mortality rate (HR: 0.67; 95% CI: 0.25 to 1.77; p = 0.42).ConclusionsThe results of this study demonstrate an important paradigm shift toward the selection of lower surgical risk patients for TAVI. Significantly better clinical outcomes can be expected in lower than in higher surgical risk patients undergoing TAVI.

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36. Prognostic Value of High-Dose Dobutamine Stress Magnetic Resonance Imaging in 1,493 Consecutive Patients Assessment of Myocardial Wall Motion and Perfusion

Author

Korosoglou, Grigorios, Elhmidi, Yacine, Steen, Henning, Schellberg, Dieter, Riedle, Nina, Ahrens, Johannes, Lehrke, Stephanie, Merten, Constanze, Lossnitzer, Dirk, Radeleff, Jannis, Zugck, Christian, Giannitsis, Evangelos, and Katus, Hugo A.

Subjects
wall motion, high-dose dobutamine stress testing, combined assessment, coronary artery disease, inducible ischemia, myocardial perfusion
Abstract

ObjectivesThis study sought to determine the prognostic value of wall motion and perfusion assessment during high-dose dobutamine stress (DS) cardiac magnetic resonance imaging (MRI) in a large patient cohort.BackgroundDS-MRI offers the possibility to integrate myocardial perfusion and wall motion analysis in a single examination for the detection of coronary artery disease (CAD).MethodsA total of 1,493 consecutive patients with suspected or known CAD underwent DS-MRI, using a standard protocol in a 1.5-T magnetic resonance scanner. Wall motion and perfusion were assessed at baseline and during stress, and outcome data including cardiac death, nonfatal myocardial infarction (“hard events”), and “late” revascularization performed >90 days after the MR scans were collected during a 2 ± 1 year follow-up period.ResultsFifty-three hard events, including 14 cardiac deaths and 39 nonfatal infarctions, occurred during the follow-up period, whereas 85 patients underwent “late” revascularization. Using multivariable regression analysis, an abnormal result for wall motion or perfusion during stress yielded the strongest independent prognostic value for both hard events and late revascularization, clearly surpassing that of clinical and baseline magnetic resonance parameters (for wall motion: adjusted hazard ratio [HR] of 5.9 [95% confidence interval (CI): 2.5 to 13.6] for hard events and of 3.1 [95% CI: 1.7 to 5.6] for late revascularization, and for perfusion: adjusted HR of 5.4 [95% CI: 2.3 to 12.9] for hard events and of 6.2 [95% CI: 3.3 to 11.3] for late revascularization, p < 0.001 for all).ConclusionsDS-MRI can accurately identify patients who are at increased risk for cardiac death and myocardial infarction, separating them from those with normal findings, who have very low risk for future cardiac events. (Prognostic Value of High Dose Dobutamine Stress Magnetic Resonance Imaging; NCT00837005)

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37. Erroneous Measurement of the Aortic Annular Diameter Using 2-Dimensional Echocardiography Resulting in Inappropriate CoreValve Size Selection A Retrospective Comparison With Multislice Computed Tomography

Author

Mylotte, Darren, Dorfmeister, Magdalena, Elhmidi, Yacine, Mazzitelli, Domenico, Bleiziffer, Sabine, Wagner, Anke, Noterdaeme, Timothee, Lange, Ruediger, and Piazza, Nicolo

Subjects
transcatheter heart valve, transesophageal echocardiography, aortic stenosis, transcatheter aortic valve replacement, computed tomography, human activities
Abstract

ObjectivesThis study sought to assess the differential adherence to transcatheter heart valve (THV)-oversizing principles between transesophageal echocardiography (TEE) and multislice computed tomography (CT) and its impact on the incidence of paravalvular leak (PVL).BackgroundCT has emerged as an alternative to 2-dimensional TEE for THV sizing.MethodsIn our early experience, TEE-derived aortic annular diameters determined THV size selection. CT datasets originally obtained for vascular screening were retrospectively interrogated to determine CT-derived annular diameters. Annular dimensions and expected THV oversizing were compared between TEE and CT. The incidence of PVL was correlated to TEE- and CT-based oversizing calculations.ResultsUsing TEE-derived annulus measurements, 157 patients underwent CoreValve implantation (23 mm: n = 66; 29 mm: n = 91). The estimated THV oversizing on the basis of TEE was 20.1 ± 8.2%. Retrospective CT analysis yielded larger annular diameters than TEE (p < 0.0001). When these CT diameters were used to recalculate the percentage of oversizing achieved with the TEE-selected CoreValve, the actual THV oversizing was only 10.4 ± 7.8%. Consequently, CT analysis suggested that up to 50% of patients received an inappropriate CoreValve size. When CT-based sizing criteria were satisfied, the incidence of PVL was 21% lower than that with echocardiography (14% vs. 35%; p = 0.003). Adherence to CT-based oversizing was independently associated with a reduced incidence of PVL (odds ratio 0.36; 95% confidence interval: 0.14 to 0.90; p = 0.029); adherence to TEE-based sizing was not.ConclusionsRetrospective CT-based annular analysis revealed that CoreValve size selection by TEE was incorrect in 50% of patients. The percentage of oversizing with CT was one-half of that calculated with TEE resulting in the majority of patients receiving a THV that was too small.

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39. Transcatheter aortic valve implantation in patients with LV dysfunction: impact on mortality and predictors of LV function recovery.

Author

Elhmidi Y, Bleiziffer S, Deutsch MA, Krane M, Mazzitelli D, Lange R, and Piazza N

Subjects
Aged, Aged, 80 and over, Aortic Valve Stenosis diagnostic imaging, Echocardiography, Female, Hemodynamics physiology, Humans, Male, Predictive Value of Tests, Regression Analysis, Retrospective Studies, Severity of Illness Index, Survival Rate, Treatment Outcome, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left physiopathology, Aortic Valve Stenosis mortality, Aortic Valve Stenosis surgery, Recovery of Function physiology, Transcatheter Aortic Valve Replacement, Ventricular Dysfunction, Left complications, Ventricular Function, Left physiology
Abstract

Background: Aortic stenosis patients with left ventricular dysfunction are at increased risk for morbidity and mortality following surgical aortic valve replacement. There are few published data regarding the outcomes of patients with severe aortic stenosis and left ventricular (LV) dysfunction undergoing transcatheter aortic valve implantation (TAVI) and possible predictors of LV recovery., Aims: To compare the baseline characteristics and outcomes between patients with normal LV function and those with LV dysfunction and to assess the predictors of LV recovery after TAVI., Methods: We enrolled 505 consecutive patients with severe aortic stenosis who underwent TAVI between November 2007 and January 2010. Patients were stratified according to LV function as follows: normal LV function (ejection fraction [EF] >50%), moderate LV dysfunction (EF 35%-50%) and severe LV dysfunction (EF ≤35%). The baseline characteristics and clinical outcomes, up to 6 months, were subsequently compared among the 3 patient subgroups. Univariable and multivariable logistic regression analyses were used to identify independent predictors of LV recovery., Results: Normal LV function was identified in 324 patients (64%) and LV dysfunction in 181 patients (36%); in those with LV dysfunction, 111 patients (22%) had moderate LV dysfunction and 70 patients (14%) had severe LV dysfunction. As compared to patients with normal LV function, those with severe LV dysfunction were more likely to be male, had higher STS and logistic EuroSCORE, more coronary artery disease/previous coronary artery bypass surgery, higher NT-proBNP levels, lower mean transaortic valve gradients, and smaller aortic valve areas. No significant difference in 30-day mortality was observed between the LV function subgroups. The 6-month mortality, however, was 2-fold higher in patients with severe LV dysfunction (27% vs 15%, respectively; P=.03). Recovery of LVEF to more than 50% was observed in 15% of patients with baseline EF ≤35%. Baseline EF was the strongest independent predictor of LV recovery after TAVI (odds ratio, 85; 95% confidence interval, 19-380; P<.001)., Conclusions: Despite a similar periprocedural outcome, patients with aortic stenosis and severe LV dysfunction exhibit a significantly increased 6-month mortality after TAVI. Survivors with LV dysfunction, however, show a significant potential for LV function recovery.

Published
2014

40. The evolution and prognostic value of N-terminal brain natriuretic peptide in predicting 1-year mortality in patients following transcatheter aortic valve implantation.

Author

Elhmidi Y, Bleiziffer S, Piazza N, Ruge H, Krane M, Deutsch MA, Hettich I, Voss B, Mazzitelli D, and Lange R

Subjects
Aged, Aged, 80 and over, Aortic Valve Stenosis metabolism, Atrial Fibrillation metabolism, Atrial Fibrillation mortality, Atrial Fibrillation surgery, Balloon Valvuloplasty methods, Biomarkers blood, Female, Follow-Up Studies, Heart Failure metabolism, Heart Failure mortality, Heart Failure surgery, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation methods, Humans, Male, Myocardium metabolism, Predictive Value of Tests, Prognosis, Prospective Studies, Risk Factors, Aortic Valve Stenosis mortality, Aortic Valve Stenosis surgery, Balloon Valvuloplasty mortality, Heart Valve Prosthesis Implantation mortality, Natriuretic Peptide, Brain blood, Peptide Fragments blood
Abstract

Aims: N-terminal pro-brain natriuretic peptide (NT-proBNP) has been found to correlate with the severity of aortic valve stenosis and to provide prognostic information in aortic stenosis patients undergoing surgical aortic valve replacement. There is a paucity of data describing the association between clinical outcomes after TAVI and NT-proBNP levels. We investigated the evolution and prognostic value of NT-proBNP levels after TAVI., Method and Results: We prospectively collected data on the baseline characteristics, NT-proBNP levels (baseline, post-treatment and discharge) and adverse clinical outcomes of patients undergoing TAVI from 2007 to 2010. Using a univariable and multivariable Cox regression model, pre- and postimplantation NT-proBNP tertile levels were correlated to 30-day and 1-year mortality. A total of 373 patients underwent TAVI with either the Medtronic CoreValve or Edwards SAPIEN prosthesis. The cumulative 30-day and 1-year mortality was 7.3% and 18%, respectively. Rehospitalization for heart failure was observed in 0.8% at 30 days and 7.8% at 1 year. The tertile baseline NT-proBNP levels were identified as ≤1570 ng/L, 1571 to 4690 ng/L and ≥4691 ng/L. In the univariable analysis, baseline (HR, 1.01; 95% CI, 1.001-1.02; P=.02) and post-treatment NT-proBNP (HR 1.02; 95% CI, 1.002-1.04; P=.04) were predictors for 1-year mortality. In the multivariable analysis, however, only baseline NT-proBNP and atrial fibrillation were identified as predictors for the 1-year mortality (HR, 1.02; 95% CI, 1.01-1.05; P=.006 and HR, 3.4; 95% CI, 1.25-9.5; P=.017, respectively)., Conclusions: NT-proBNP and atrial fibrillation were predictors for 1-year mortality, offer independent prognostic information, and identify patients being at increased risk for mortality. Thus, NT-proBNP reveals more incremental value for patient selection and should be included in the risk stratification of patients undergoing TAVI.

Published
2013

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