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A self‐healable hydrogel for advanced authentication applications was successfully developed. In the presence of an aqueous solution of ammonium hydroxide as a cheap passivating agent, the hydrothermal carbonization of cellulose diacetate extracted from rice straw yielded nitrogen‐doped carbon dots (NdCD) in a straightforward and ecologically beneficial manner. NdCD achieved a maximum quantum yield of 25.11%. Self‐healing biocomposite inks with different emission properties were created by using different concentrations of NdCD nanoparticles (NPs). In order to create a transparent layer of NdCD@PLA hydrogel, stamps were used to press homogenous films onto paper surfaces. Polylactic acid (PLA) hydrogel was embedded with NPs of NdCD. Self‐healing security hydrogel inks are highly durable. The NdCD@PLA hydrogel is efficiently self‐healable at room temperature. The current NdCD@PLA hydrogel can attach to different surfaces, such as glasses, plastics, and papers. The self‐healable nanobiocomposite was photostable when exposed to UV light. Under UV light, NdCD‐containing nanobiocomposite inks have a bluish color, as proved by both colorimetric parameters and fluorescence spectra. The morphological properties of NdCD were studied by transmission electron microscopy to suggest a particle diameter of 10–15 nm. The morphology of the fluorescent prints was analyzed using a number of different analytical methods. The hydrogel rheology and the mechanical performance of printed papers were tested. The printed films showed excitation and fluorescence bands at 401 and 488 nm, respectively. The present smart ink shows significant promise as a potential industrial production technique to simply produce anti‐counterfeiting prints. Highlights: Rice straws were used to prepare nitrogen‐doped carbon dots with a quantum yield of 25.11%.Self‐healable polylactic acid hydrogel was immobilized with N‐doped carbon dots (10–15 nm).Transparent printed films shifted in color to blue (488 nm) when excited at 401 nm.Ultraviolet‐stimulated photochromic authentication prints were prepared.Printed paper demonstrated non‐cytotoxicity, high photostability, and durability. [ABSTRACT FROM AUTHOR]

In the current paper, nickel oxide nanoparticles (NiO NPs) was successfully applied as a sustainable effective and recoverable catalyst for the preparation of 2-amino-4H pyran derivatives 2-11 via one-pot, threecomponent reaction of 4-formylphenyl-4-methyl benzenesulfonate (1) with malononitrile and active methylene compounds in green solvent water and ethanol in ratio (3:1) in excellent yield (95-98%) and shorter reaction time (5-8 min). The structures of the pyran derivatives were elucidated by elemental and spectral analyses such as IR, 1H NMR, 13C NMR and DEPT 135 spectra. Moreover, the characterization of the catalyst after and before the reaction were studied using X-ray diffraction (X-RD), scanning electron microscope (SEM), EDX techniques and IR-spectra. It has been indicated that catalyst has the same efficiency. The application of this protocol has many advantages such as eco-friendly, inexpensive, simple protocol and easy recovery of the catalyst. Overall products are designed, synthesized and studied for their anti-microbial evaluation. It has been found that is compounds 2, 3, 7 and 10 are the most active against antibacterial compression with the stander drug Ampicillin. On the other hand, Compounds 2, 3, 8, and 11 displayed the most promising antifungal activities with Amphotericin B. [ABSTRACT FROM AUTHOR]

The primary objective of the current framework was to synthesize novel mononuclear 1:1:1 complexes involving FeLG, CoLG, NiLG, CuLG, and ZnLG, where the ligand (L) is identified as 4-[(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)hydrazono]methylphenyl-4-methylbenzenesulfonate, and glycine (G) serves as the coligand. Comprehensive characterization of the investigated complexes was achieved through various analytical techniques, including FTIR, UV-Vis spectroscopy, elemental analysis, mass spectra, magnetic susceptibility measurements, molar conductivity assessments, and thermogravimetric analysis (TGA). The determination of stoichiometry was performed employing the molar ratio technique, revealing the octahedral geometry inherent in the isolated metal complexes. Employing a density functional theory (DFT) approach, the molecular structures of the designated compounds were theoretically elevated, and quantum chemical descriptors were derived to provide a deeper insight into their electronic properties. Furthermore, the inhibitory potential of these compounds against fungal strains and pathogenic bacteria prevalent in the Arab environment was evaluated using the disc diffusion method, emphasizing their role in combating diseases affecting humans, animals, and plants. Notably, the metal complexes exhibited superior antibacterial activity, as evidenced by a higher activity index. Molecular docking investigations were conducted to ascertain the inhibitory effects of the compounds on the 1FJ4 protein, with ZnLG emerging as the compound with the highest binding affinity. These results suggest the promising candidacy of these compounds as antimicrobial agents, particularly in the context of combating bacterial and fungal infections. [ABSTRACT FROM AUTHOR]

The present framework has as its goal the design and synthesis and characterization of new mononuclear 1:1:1 (M:L:Q) mixed-ligand complexes, including FeLQ, CoLQ, NiLQ, CuLQ, and ZnLQ. The "L," is the 4-[(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)hydrazono]methylphenyl 4-methylbenzenesulfonate, while the "Q," is the 8-hydroxy quinoline. According to the findings, L and Q ligands each play the role of a neutral bi-dentate NN and a monobasic bi-dentate ON ligand, respectively. The findings demonstrated an octahedral shape. The density functional theory (DFT) technique was employed, and the quantum chemical descriptors were assessed, to optimize the molecular structure of the compounds. An in vitro investigation was carried out to investigate the antibacterial and antifungal activities of the compounds. According to the findings, the activity of metal complexes as potential candidates for use as antibiotics and antifungals is much greater than that of their free ligands. The in-silico inhibition of the 1fj4 protein was investigated using molecular docking. ZnLQ complex was the one that inhibited the 1fj4 protein with the greatest degree of success. The fact that this is the case lends credence to the notion that these compounds have the potential to function as launchpads for the development of new classes of antibiotics. [ABSTRACT FROM AUTHOR]

Through the condensation of isatin (indoline-2, 3-dione) and aniline in a 1:1 ratio, a Schiff base ligand was synthesized and characterized via (1H-NMR, mass, IR, UV-Vis) spectra. Elemental analyses, spectroscopy (1H-NMR, mass, UV-Vis), magnetic susceptibility, molar conductivity, mass spectra, scanning electron microscope (SEM), and thermal analysis have all been used to characterize a series of Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) metal complexes derived from the titled ligand. The metal-to-ligand ratio is 1:1, according to the analytical data. The Schiff base ligand displayed bidentate behavior with NO coordination sites when it bonded to metal ions, as seen by the IR spectra. The magnetic moment measurement and UV-Vis spectral investigation showed the octahedral geometry of the Cr(III), Fe(III), Co(II), Ni(II), and Zn(II) complexes, whereas they suggested the tetrahedral geometry of the Mn(II), Cu(II), and Cd(II) complexes. The thermal analysis study confirmed the presence of both hydrated and coordinated water molecules in all the compounds, except for the Mn(II) complex, and showed that the complexes decomposed in three or five decomposition steps leaving the corresponding metal oxide as a residue. The ligand and its metal complexes' antibacterial efficacy were evaluated. The findings showed that the metal complexes had stronger antibacterial properties than the ligand alone. The ligand and its metal complexes' anticancer properties were also investigated. A DFT investigation is also reported to gather information regarding the electronic features of the ligand and its metal complexes. Finally, drug-likeness and ADME characteristics were also calculated as parameters. [ABSTRACT FROM AUTHOR]

The present context is a pioneer attempt to verify the ability of copepod, Lernanthropus kroyeri (L. kroyeri), to uptake and accumulate heavy metals. We primarily assess the prevalence of the parasite in various seasons and its clinical signs, as well as post-mortem changes in sea bass (Moron labrax). The morphological features of the parasite using a light microscope, the bioaccumulation of heavy metals in the tissues of both L. kroyeri and M. labrax (gills, muscles) using Flame Atomic Absorption Spectrometry, and the histopathological alterations were monitored. Fish (n = 200) were obtained from Ezbet Elborg and examined for the parasite, L. kroyeri. The results revealed that the total infection was recorded at 86%. The infested fish exhibited excessive mucous and ulceration at the site of attachment. The post-mortem lesion in the gills revealed a marbling appearance with destructed filaments. Various heavy metals (Zn, Co, Cu, and Cd) were detected in the tissues of L. kroyeri and M. labrax and, surprisingly, L. kroyeri had the ability to uptake and accumulate a high amount of Zn in its tissues. Infested fish accumulated a lower concentration of Zn in their tissue compared with the non-infested ones. Within the host tissue, the accumulation of Zn was higher in the gills compared with the muscles. The histopathological findings demonstrated scattered parasitic elements with the destruction of the gill lamellae. Taken together, we highlight the potential role of L. kroyeri to eliminate Zn and it can be utilized as a bio-indicator for metal monitoring studies for sustaining aquaculture. [ABSTRACT FROM AUTHOR]