The present paper proposes a novel methodology of turbocharging automotive engines to reach targeted performance. The actual method is tested and validated against simulation test results of two turbocharged diesel engines; engine I, three cylinders, 1.5 L, and engine II, six cylinders, 5.9 L. The present procedure is subdivided into four key parts; namely, database construction, selection procedure, turbocharger preliminary design, and engine modeling. Based on geometric dimensions and aerodynamic parameters provided by the preliminary design procedure, 3D geometries of the turbine and compressor are generated for each studied engine. After integrating previous data into a constructed turbocharger database, two turbochargers are selected for the engine I, while only one turbocharger for the engine II. The findings show that, at the engine speed of 4000 rpm, engine I matched with the adequate turbocharger reached a target power about 2.7%, compared to the original turbocharger equipping engine I. Furthermore, engine II reached a rated power of 299.3 kW at 2500 rpm which is slightly under the original one by 2.64 kW. The superimposition of the engine operating area on compressor and turbine maps provided satisfactory results in terms of turbocharger-engine output performance, fuel consumption, secure functioning and engine thermal strength. Finally, the main advantage of the developed methodology consists of its ability to be applied at both earlier and last stages of the engine turbocharging process or to find new adequate turbochargers to replace the original one for economic, mechanical or for safety reasons. [ABSTRACT FROM AUTHOR]