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Your search keyword '"El Fray, Miroslawa"' showing total 315 results
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315 results on '"El Fray, Miroslawa"'

24. Development of the Mobile PoC Graphene-Based Biosensing Device Using Electrochemical Impedance Spectroscopy (EIS)

Author

Matias, Daniel, Przeniosło, Łukasz, Miłosławski, Tomasz, Jaskuła, Marek, Makiewicz, Przemysław, Biegun, Marcin, Penkala, Krzysztof, Mijowska, Ewa, El Fray, Mirosława, Podolski, Jacek, MAGJAREVIC, Ratko, Editor-in-chief, Ładyzynsk, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, and Jobbágy, Ákos, editor

Published
2015
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29. New Eco-Friendly, Biocompatible, Bactericidal, Fungicidal and Anticancer-Activity-Exhibiting Nanocomposites Based on Bimetallic TiO 2 @Cr 2 O 3 Nanoparticle Core and Biopolymer Shells.

Author

Hasanin, Mohamed S., Elhenawy, Yasser, Abdel-Hamid, Shereen M. S., Fouad, Yasser, Monica, Toderaș, Al-Qabandi, O. A., El Fray, Miroslawa, and Bassyouni, Mohamed

Subjects
NANOPARTICLES, TITANIUM dioxide, NANOCOMPOSITE materials, STABILIZING agents, ETHYLCELLULOSE, BIOPOLYMERS
Abstract

Nanoparticles have attracted substantial attention for their diverse range of applications, particularly in biomedicine applications and drug delivery, owing to their unique properties. However, their tiny size facilitates easy cellular entry, which can also lead to interactions with cellular components, potentially resulting in toxicity and undesirable effects. In this study, a novel nanocomposite formulation was developed using biopolymers, specifically ethylcellulose and collagen, as capping and stabilizing agents to create bimetallic nanoparticles including TiO2@Cr2O3 nanoparticles. Physicochemical and morphological analyses were carried out to validate the formulation's structure. The obtained characteristics emphasized the presence of a nanostructure involving bimetallic nanoparticles. This formulation exhibited excellent biological activity, including high biocompatibility with Vero and WI38 cells at concentrations of 40.4 and 52 µg/mL, respectively, as well as effective anticancer activity with significant selectivity. The IC50 values were determined to be 19 and 22 µg/mL for MCF7 and A549 cells, respectively. The antimicrobial assessment revealed the highest MIC value for A. niger at 50 µg/mL, while the lowest MIC value was observed for Gram-positive bacteria at 3.12 µg/mL. Additionally, the nanocomposite demonstrated antioxidant activity at a low concentration of 1.5 µg/mL. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Poly(butylene-succinate)-based blends with enhanced oxygen permeability

Author

Kantor-Malujdy, Nina, Skowron, Sandra, and El Fray, Miroslawa

Abstract

Poly(butylene succinate) (PBS) is a biodegradable polymer produced from renewable raw materials and is widely used in the production of packaging materials. Among important features, oxygen permeability is crucial for “breathing” packaging materials (such as packaging for medical devices sterilized with gaseous ethylene oxide). Recently, poly(butylene succinate-dilinolene succinate) (PBS-DLS) copolymers containing long chains of fatty acids and showing excellent elasticity were synthesized. In this work, bio-based polymer blends of PBS and PBS-DLS copolymer with an aliphatic-aromatic poly(butylene terephthalate-butylene adipate) (PBAT) (Ecoflex) were prepared in order to further improve their oxygen permeability while maintaining mechanical stability. PBS and PBS-DLS copolymer containing 90 wt% of hard segments and 10 wt% of soft segments, respectively, were used for blends preparation with 10 wt% of PBAT. The chemical structure was analyzed using infrared spectroscopy and thermal properties were determined with differential scanning calorimetry. The introduction of PBAT to the blends did not affect their melting temperatures. The mechanical properties of the blends are also similar to separate ones.The melt flow index and hardness were determined and the mechanical and barrier properties were also examined. Importantly, the oxygen permeability of PBS-DLS/PBAT blend was comparable to non-biodegradable high-density polyethylene (HDPE) Tyvek used for medical devices packaging.

Published
2022
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