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The objective of this study is to investigate a possible correlation between anxiety status and anti-Mullerian hormone (AMH) levels among healthcare professionals who provide medical care directly to COVID-19-positive patients during the recent pandemic. Fifty-two healthcare professionals (nurses, midwives, and residents) who provide medical care directly to COVID-19-positive patients in inpatient clinics or intensive care units were enrolled in this study. Serum AMH levels were analyzed to reflect ovarian reserve. The Beck Anxiety Inventory (BAI) and the State-Trait Anxiety Inventory (STAI-S and STAI-T, respectively) were completed by participants to assess their anxiety status. A linear regression model with participant age as the constant variable was applied to analyze the relationship between inventory scale scores and AMH levels. P-values less than 0.05 were considered statistically significant. The mean AMH value was significantly lower for the participants in the moderate/severe anxiety group compared to the minimal/mild anxiety group (p = 0.007). A linear regression analysis revealed a significant negative correlation between AMH levels and both BAI (B = -0.030, standard error = 0.010, p = 0.004) and STAI-S and STAI-T scores when age was controlled (both p = 0.003). The severity of anxiety experienced during the recent COVID-19 pandemic among healthcare professionals, who provide medical care directly to COVID-19-positive patients, is found to be related to low AMH levels.

Objective To investigate the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity in asymptomatic pregnant women admitted to hospital for delivery in a Turkish pandemic center. Study Design This prospective cohort study was conducted in Ankara City Hospital between April, 15, 2020 and June, 5, 2020. A total of 206 asymptomatic pregnant women (103 low-risk pregnant women without any defined risk factor and 103 high-risk pregnant women) were screened for SARS-CoV-2 positivity upon admission to hospital for delivery. Detection of SARS-CoV2 in nasopharyngeal and oropharyngeal samples was performed by Real Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) method targeting RdRp (RNA dependent RNA polymerase) gene. Two groups were compared in terms of demographic features, clinical characteristics and SARS-CoV-2 positivity. Results Three of the 206 pregnant women participating in the study had positive RT-PCR tests (1.4 %) and all positive cases were in the high-risk pregnancy group. Although, one case in the high-risk pregnancy group had developed symptoms highly suspicious for COVID-19, two repeated RT-PCR tests were negative. SARS-CoV-2 RT-PCR positivity rate was significantly higher in the high-risk pregnancy group (2.9 % vs 0%, p = 0.04). Conclusion Healthcare professionals should be cautious in the labor and delivery of high-risk pregnant women during the pandemic period and universal testing for COVID-19 may be considered in selected populations.

To compare the effects of oxytocin and dinoprostone used in labor induction on fetal blood gas parameters.This prospective randomized trial involved 108 women who completed 37 gestational weeks and who required labor induction prior to normal vaginal birth. Labor was induced in 57 women with an intravenous low dose oxytocin regimen and in 51 with intravaginal dinoprostone (PGE2). Following childbirth, umbilical artery blood gas was analyzed, with pH, pCO2, pO2, HCO3 and base excess (BE) compared in the two groups.Mean age and obstetrical data (gravidity, parity, gestational weeks and birthweight) were similar in the two groups (p0.05). All infants had 1 and 5 minute APGAR scores ≥7. Umbilical artery blood pH was similar in the oxytocin and dinoprostone groups (7.31±0.07 vs. 7.31±0.05, p=0.780), as were the other blood gas parameters (pCO2, pO2, base excess and HCO3; p0.05 each).Induction of labor with either oxytocin or dinoprostone in women with uncomplicated term pregnancies had no adverse effects on umbilical artery blood gas parameters.Bu çalışmada amacımız, doğum indüksiyonunda kullanılan iki metod olan oksitosin ve dinoprostonun fetal kan gazı parametreleri üzerine olan etkilerinin karşılaştırılmasıdır.Bu prospektif randomize çalışmaya 37 gebelik haftasını doldurmuş ve doğum eylemi indüksiyonu uygulanan ve vajinal yoldan doğumu gerçekleşen 108 olgu alındı. Eylem indüksiyonu için 57 olguya intravenöz yolla oksitosin, 51 olguya ise intravajinal dinoproston (PG Eİki grup arasında ortalama yaş ve obstetrik değişkenler (gravida, parite, gebelik haftası ve doğum ağırlığı) benzer saptandı (p0.05). Tüm olgularda 1. ve 5. dakika Apgar skoru ≥7 idi. Umbilikal arter kan pH değeri oksitosin grubunda 7.31±0.07 iken ; dinoproston grubunda 7.31±0.05 olarak izlendi (p=0.780). Diğer kan gazı parameterleri değerlendirildiğinde de (pCOKomplike olmayan term gebeliklerde doğum eylemi indüksiyonununda kullanılan iki metod olan oksitosin ve dinoprostonun fetal kan gazı parametreleri üzerine olumsuz etkisi yoktur.

SUMMARY Cervical ectopic pregnancy, a rare situation that constitues %0,2 of all ectopic pregnancies and initative high maternal mortality. Early diagnosis and appropriate treatment in this patients is life saving and helps to preserve fertility .This paper describes diagnosis, follow up and conservative treatment of three cervical ectopic pregnancy cases.