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1. Impact of 18FFDG-PET/CT and Laparoscopy in Staging of Locally Advanced Gastric Cancer: A Cost Analysis in the Prospective Multicenter PLASTIC-Study

Author

de Jongh, Cas, van der Meulen, Miriam P., Gertsen, Emma C., Brenkman, Hylke J. F., van Sandick, Johanna W., van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., Luyer, Misha D. P., Nieuwenhuijzen, Grard A. P., van Lanschot, Jan J. B., Lagarde, Sjoerd M., Wijnhoven, Bas P. L., de Steur, Wobbe O., Hartgrink, Henk H., Stoot, Jan H. M. B., Hulsewe, Karel W. E., Spillenaar Bilgen, Ernst Jan, van Det, Marc J., Kouwenhoven, Ewout A., Daams, Freek, van der Peet, Donald L., van Grieken, Nicole C. T., Heisterkamp, Joos, van Etten, Boudewijn, van den Berg, Jan-Willem, Pierie, Jean-Pierre, Eker, Hasan H., Thijssen, Annemieke Y., Belt, Eric J. T., van Duijvendijk, Peter, Wassenaar, Eelco, Wevers, Kevin P., Hol, Lieke, Wessels, Frank J., Haj Mohammad, Nadia, Frederix, Geert W. J., van Hillegersberg, Richard, Siersema, Peter D., Vegt, Erik, and Ruurda, Jelle P.

Published
2024
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3. Contributors

Author

Berrevoet, F., primary, Braat, Andries E., additional, Broere, Roberto, additional, Cassese, Gianluca, additional, Dahlqvist, Geraldine, additional, de Hemptinne, Bernard, additional, de Jonge, Jeroen, additional, Degroote, Helena, additional, Durand, François, additional, Eker, Hasan H., additional, Luijmes, Stefan H., additional, Raevens, Sarah, additional, Troisi, Roberto Ivan, additional, Van Vlierberghe, Hans, additional, and Verhelst, Xavier, additional

Published
2024
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4. Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement vs. primary suture only in midline laparotomies (PRIMA): long-term outcomes of a multicentre, double-blind, randomised controlled trial

Author

Grotelüschen, Rainier, Roumen, Rudie, van Baardewijk, Laurens, van Brussel, Jerome, van den Berg, Michiel, Boomsma, Martijn, Dwarkasing, Roy, van der Wal, Maarten, Buijk, Steven, Jairam, An, Burger, Pim C.W., Verhagen, Hence, De Jong, D., Klitsie, Pieter, Lases, Lenny, van der Ham, Arie, Harlaar, Joris, Charbon, Jan, Leenders, Bart, Dawson, Imro, Seiler, Christof, Buchler, Markus, Diener, Markus, Schuhmacher, Christoph, Izbicki, Jakob, Kutup, Asad, Neuhaus, Peter, Fikatas, Panagiotis, Golling, Markus, Laux, Dirk, May, Christopher, Nieuwenhuizen, Jeroen, Eker, Hasan H., Van den Dop, Louis Matthijs, Sneiders, Dimitri, Yurtkap, Yagmur, Werba, Alexander, van Klaveren, David, Pierik, Robert E.G.J.M., Reim, Daniel, Timmermans, Lucas, Fortelny, René H., Mihaljevic, André L., Kleinrensink, Gert-Jan, Tanis, Pieter J., Lange, Johan F., and Jeekel, Johannes

Published
2024
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5. Factors associated with failure to rescue after liver resection and impact on hospital variation: a nationwide population-based study

Author

te Riele, Wouter W., Buis, Carlijn I., Patijn, Gijs A., Braat, Andries E., Dejong, Cornelis H.C., Hoogwater, Frederik J.H., Molenaar, I.Q., Besselink, Marc G.H., Verhoef, Cornelis, Eker, Hasan H., van der Hoeven, Joost A.B., van Heek, N. Tjarda, Torrenga, Hans, Bosscha, Koop, Vermaas, Maarten, Consten, Esther C.J., Oosterling, Steven J., Elfrink, Arthur K.E., Olthof, Pim B., Swijnenburg, Rutger-Jan, den Dulk, Marcel, de Boer, Marieke T., Mieog, J. Sven D., Hagendoorn, Jeroen, Kazemier, Geert, van den Boezem, Peter B., Rijken, Arjen M., Liem, Mike S.L., Leclercq, Wouter K.G., Kuhlmann, Koert F.D., Marsman, Hendrik A., Ijzermans, Jan N.M., van Duijvendijk, Peter, Erdmann, Joris I., Kok, Niels F.M., Grünhagen, Dirk J., and Klaase, Joost M.

Published
2021
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6. Short-term postoperative outcomes after liver resection in the elderly patient: a nationwide population-based study

Author

Eker, Hasan H., Belt, Eric T.J., van Heek, N.Tjarda, Torrenga, Hans, Bosscha, Koop, Doornebosch, Pascal, Consten, Esther C.J., Oosterling, Steven J., de Boer, Marieke T., Besselink, Marc G.H., Dejong, Cornelis H.C., te Riele, Wouter W., Hoogwater, Frederik J.H., Liem, Mike S.L., Molenaar, I.Quintus, Swijnenburg, Rutger-Jan, Braat, Andries E., Elfrink, Arthur K.E., Kok, Niels F.M., den Dulk, Marcel, Buis, Carlijn I., Kazemier, Geert, Ijzermans, Jan N.M., Lam, Hwai-Ding, Hagendoorn, Jeroen, van den Boezem, Peter B., Ayez, Ninos, Zonderhuis, Babs M., Lips, Daan J., Leclercq, Wouter K.G., Kuhlmann, Koert F.D., Marsman, Hendrik A., Verhoef, Cornelis, Patijn, Gijs A., Grünhagen, Dirk J., and Klaase, Joost M.

Published
2021
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7. Hospital variation in combined liver resection and thermal ablation for colorectal liver metastases and impact on short-term postoperative outcomes: a nationwide population-based study

Author

te Riele, Wouter W., de Boer, Marieke T., Dejong, Cees H.C., van Gulik, Thomas H., Hoogwater, Frederik J.H., Molenaar, I.Q., van der Leij, Christiaan, Moelker, Adriaan, Besselink, Marc G.H., Buis, Carlijn I., den Dulk, Marcel, Bosscha, Koop, Belt, Eric J.Th., Vermaas, Maarten, van Heek, Tjarda N.T., Oosterling, Steven J., Torrenga, Hans, Eker, Hasan H., Consten, Esther C.J., Elfrink, Arthur K.E., Nieuwenhuizen, Sanne, van den Tol, M. Petrousjka, Burgmans, Mark C., Prevoo, Warner, Coolsen, Marielle M.E., van den Boezem, Peter B., van Delden, Otto M., Hagendoorn, Jeroen, Patijn, Gijs A., Leclercq, Wouter K.G., Liem, Mike S.L., Rijken, Arjen M., Verhoef, Cornelis, Kuhlmann, Koert F.D., Ruiter, Simeon J.S., Grünhagen, Dirk J., Klaase, Joost M., Kok, Niels F.M., Meijerink, Martijn R., and Swijnenburg, Rutger-Jan

Published
2021
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8. A simplified primary aldosteronism surgical outcome score is a useful prediction model when target organ damage is unknown – Retrospective cohort study

Author

Zarnegar, Rasa, Fahey, Thomas J., Duh, Quan Y., Shen, Wen T., Drake, Frederick T., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Sturgeon, Cord, Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Sidhu, Stan B., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Engelsman, Anton F., van Dijkum, Els J.M. Nieveen, Kerstens, Michiel N., Kruijff, Schelto, Suurd, Diederik P.D., Visscher, Wouter P., Vorselaars, Wessel M.C.M., van Beek, Dirk-Jan, Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., and Vriens, Menno R.

Published
2021
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9. Impact of 18FFDG-PET/CT and Laparoscopy in Staging of Locally Advanced Gastric Cancer:A Cost Analysis in the Prospective Multicenter PLASTIC-Study

Author

de Jongh, Cas, Gertsen, Emma C., van der Meulen, Miriam P., Brenkman, Hylke J.F., van Sandick, Johanna W., van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., Luyer, Misha D.P., Nieuwenhuijzen, Grard A.P., van Lanschot, Jan J.B., Lagarde, Sjoerd M., Wijnhoven, Bas P.L., de Steur, Wobbe O., Hartgrink, Henk H., Stoot, Jan H.M.B., Hulsewe, Karel W.E., Spillenaar Bilgen, Ernst Jan, van Det, Marc J., Kouwenhoven, Ewout A., Daams, Freek, van der Peet, Donald L., van Grieken, Nicole C.T., Heisterkamp, Joos, van Etten, Boudewijn, van den Berg, Jan Willem, Pierie, Jean Pierre, Eker, Hasan H., Thijssen, Annemieke Y., Belt, Eric J.T., van Duijvendijk, Peter, Wassenaar, Eelco, Wevers, Kevin P., Hol, Lieke, Wessels, Frank J., Haj Mohammad, Nadia, Frederix, Geert W.J., van Hillegersberg, Richard, Siersema, Peter D., Vegt, Erik, Ruurda, Jelle P., de Jongh, Cas, Gertsen, Emma C., van der Meulen, Miriam P., Brenkman, Hylke J.F., van Sandick, Johanna W., van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., Luyer, Misha D.P., Nieuwenhuijzen, Grard A.P., van Lanschot, Jan J.B., Lagarde, Sjoerd M., Wijnhoven, Bas P.L., de Steur, Wobbe O., Hartgrink, Henk H., Stoot, Jan H.M.B., Hulsewe, Karel W.E., Spillenaar Bilgen, Ernst Jan, van Det, Marc J., Kouwenhoven, Ewout A., Daams, Freek, van der Peet, Donald L., van Grieken, Nicole C.T., Heisterkamp, Joos, van Etten, Boudewijn, van den Berg, Jan Willem, Pierie, Jean Pierre, Eker, Hasan H., Thijssen, Annemieke Y., Belt, Eric J.T., van Duijvendijk, Peter, Wassenaar, Eelco, Wevers, Kevin P., Hol, Lieke, Wessels, Frank J., Haj Mohammad, Nadia, Frederix, Geert W.J., van Hillegersberg, Richard, Siersema, Peter D., Vegt, Erik, and Ruurda, Jelle P.

Abstract

Background: Unnecessary D2-gastrectomy and associated costs can be prevented after detecting non-curable gastric cancer, but impact of staging on treatment costs is unclear. This study determined the cost impact of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18FFDG-PET/CT) and staging laparoscopy (SL) in gastric cancer staging. Materials and Methods:In this cost analysis, four staging strategies were modeled in a decision tree: (1) 18FFDG-PET/CT first, then SL, (2) SL only, (3) 18FFDG-PET/CT only, and (4) neither SL nor 18FFDG-PET/CT. Costs were assessed on the basis of the prospective PLASTIC-study, which evaluated adding 18FFDG-PET/CT and SL to staging advanced gastric cancer (cT3–4 and/or cN+) in 18 Dutch hospitals. The Dutch Healthcare Authority provided 18FFDG-PET/CT unit costs. SL unit costs were calculated bottom-up. Gastrectomy-associated costs were collected with hospital claim data until 30 days postoperatively. Uncertainty was assessed in a probabilistic sensitivity analysis (1000 iterations). Results: 18FFDG-PET/CT costs were €1104 including biopsy/cytology. Bottom-up calculations totaled €1537 per SL. D2-gastrectomy costs were €19,308. Total costs per patient were €18,137 for strategy 1, €17,079 for strategy 2, and €19,805 for strategy 3. If all patients undergo gastrectomy, total costs were €18,959 per patient (strategy 4). Performing SL only reduced costs by €1880 per patient. Adding 18FFDG-PET/CT to SL increased costs by €1058 per patient; IQR €870–1253 in the sensitivity analysis. Conclusions:For advanced gastric cancer, performing SL resulted in substantial cost savings by reducing unnecessary gastrectomies. In contrast, routine 18FFDG-PET/CT increased costs without substantially reducing unnecessary gastrectomies, and is not recomme

Published
2024

10. Clinical outcomes after surgery for primary aldosteronism: Evaluation of the PASO-investigators’ consensus criteria within a worldwide cohort of patients

Author

Zarnegar, Rasa, Drake, Frederick T., Duh, Quan Y., Talutis, Stephanie D., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D’Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, Nina M., Nieveen van Dijkum, Els J.M., Metman, Madelon J.H., Kruijff, Schelto, Vorselaars, Wessel M.C.M., van Beek, Dirk-Jan, Postma, Emily L., Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., and Vriens, Menno R.

Published
2019
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11. Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement vs. primary suture only in midline laparotomies (PRIMA): long-term outcomes of a multicentre, double-blind, randomised controlled trial

Author

Van den Dop, Louis Matthijs, primary, Sneiders, Dimitri, additional, Yurtkap, Yagmur, additional, Werba, Alexander, additional, van Klaveren, David, additional, Pierik, Robert E.G.J.M., additional, Reim, Daniel, additional, Timmermans, Lucas, additional, Fortelny, René H., additional, Mihaljevic, André L., additional, Kleinrensink, Gert-Jan, additional, Tanis, Pieter J., additional, Lange, Johan F., additional, Jeekel, Johannes, additional, Grotelüschen, Rainier, additional, Roumen, Rudie, additional, van Baardewijk, Laurens, additional, van Brussel, Jerome, additional, van den Berg, Michiel, additional, Boomsma, Martijn, additional, Dwarkasing, Roy, additional, van der Wal, Maarten, additional, Buijk, Steven, additional, Jairam, An, additional, Burger, Pim C.W., additional, Verhagen, Hence, additional, De Jong, D., additional, Klitsie, Pieter, additional, Lases, Lenny, additional, van der Ham, Arie, additional, Harlaar, Joris, additional, Charbon, Jan, additional, Leenders, Bart, additional, Dawson, Imro, additional, Seiler, Christof, additional, Buchler, Markus, additional, Diener, Markus, additional, Schuhmacher, Christoph, additional, Izbicki, Jakob, additional, Kutup, Asad, additional, Neuhaus, Peter, additional, Fikatas, Panagiotis, additional, Golling, Markus, additional, Laux, Dirk, additional, May, Christopher, additional, Nieuwenhuizen, Jeroen, additional, and Eker, Hasan H., additional

Published
2023
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13. Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial

Author

Nieuwenhuizen, Jeroen, Hop, Wim C J, Burger, Pim C W, Verhagen, Hence J, Klitsie, Pieter J, van de Berg, Michiel, Golling, Markus, Jairam, An P, Timmermans, Lucas, Eker, Hasan H, Pierik, Robert E G J M, van Klaveren, David, Steyerberg, Ewout W, Timman, Reinier, van der Ham, Arie C, Dawson, Imro, Charbon, Jan A, Schuhmacher, Christoph, Mihaljevic, André, Izbicki, Jakob R, Fikatas, Panagiotis, Knebel, Philip, Fortelny, René H, Kleinrensink, Gert-Jan, Lange, Johan F, and Jeekel, Hans J

Published
2017
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17. Colorectal liver metastases: surgery versus thermal ablation (COLLISION) – a phase III single-blind prospective randomized controlled trial

Author

Puijk, Robbert S., Ruarus, Alette H., Vroomen, Laurien G. P. H., van Tilborg, Aukje A. J. M., Scheffer, Hester J., Nielsen, Karin, de Jong, Marcus C., de Vries, Jan J. J., Zonderhuis, Babs M., Eker, Hasan H., Kazemier, Geert, Verheul, Henk, van der Meijs, Bram B., van Dam, Laura, Sorgedrager, Natasha, Coupé, Veerle M. H., van den Tol, Petrousjka M. P., Meijerink, Martijn R., and COLLISION Trial Group

Published
2018
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18. Diagnosis and management of acute appendicitis. EAES consensus development conference 2015

Author

Gorter, Ramon R., Eker, Hasan H., Gorter-Stam, Marguerite A. W., Abis, Gabor S. A., Acharya, Amish, Ankersmit, Marjolein, Antoniou, Stavros A., Arolfo, Simone, Babic, Benjamin, Boni, Luigi, Bruntink, Marlieke, van Dam, Dieuwertje A., Defoort, Barbara, Deijen, Charlotte L., DeLacy, F. Borja, Go, Peter MNYH, Harmsen, Annelieke M. K., van den Helder, Rick S., Iordache, Florin, Ket, Johannes C. F., Muysoms, Filip E., Ozmen, M. Mahir, Papoulas, Michail, Rhodes, Michael, Straatman, Jennifer, Tenhagen, Mark, Turrado, Victor, Vereczkei, Andras, Vilallonga, Ramon, Deelder, Jort D., and Bonjer, Jaap

Published
2016
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22. Nationwide oncological networks for resection of colorectal liver metastases in the Netherlands: Differences and postoperative outcomes

Author

Elfrink, Arthur K.E., primary, Kok, Niels F.M., additional, Swijnenburg, Rutger-Jan, additional, den Dulk, Marcel, additional, van den Boezem, Peter B., additional, Hartgrink, Henk H., additional, te Riele, Wouter W., additional, Patijn, Gijs A., additional, Leclercq, Wouter K.G., additional, Lips, Daan J., additional, Ayez, Ninos, additional, Verhoef, Cornelis, additional, Kuhlmann, Koert F.D., additional, Buis, Carlijn I., additional, Bosscha, Koop, additional, Belt, Eric J.T., additional, Vermaas, Maarten, additional, van Heek, N.Tjarda, additional, Oosterling, Steven J., additional, Torrenga, Hans, additional, Eker, Hasan H., additional, Consten, Esther C.J., additional, Marsman, Hendrik A., additional, Kazemier, Geert, additional, Wouters, Michel W.J.M., additional, Grünhagen, Dirk J., additional, Klaase, Joost M., additional, Dejong, Cornelis H.C., additional, Besselink, Marc G.H., additional, de Boer, Marieke T., additional, Braat, Andries E., additional, Hagendoorn, Jeroen, additional, Hoogwater, Frederik J.H., additional, and Molenaar, I. Quintus, additional

Published
2022
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23. Factors associated with failure to rescue after liver resection and impact on hospital variation: a nationwide population-based study

Author

Elfrink, Arthur K.E., primary, Olthof, Pim B., additional, Swijnenburg, Rutger-Jan, additional, den Dulk, Marcel, additional, de Boer, Marieke T., additional, Mieog, J. Sven D., additional, Hagendoorn, Jeroen, additional, Kazemier, Geert, additional, van den Boezem, Peter B., additional, Rijken, Arjen M., additional, Liem, Mike S.L., additional, Leclercq, Wouter K.G., additional, Kuhlmann, Koert F.D., additional, Marsman, Hendrik A., additional, Ijzermans, Jan N.M., additional, van Duijvendijk, Peter, additional, Erdmann, Joris I., additional, Kok, Niels F.M., additional, Grünhagen, Dirk J., additional, Klaase, Joost M., additional, te Riele, Wouter W., additional, Buis, Carlijn I., additional, Patijn, Gijs A., additional, Braat, Andries E., additional, Dejong, Cornelis H.C., additional, Hoogwater, Frederik J.H., additional, Molenaar, I.Q., additional, Besselink, Marc G.H., additional, Verhoef, Cornelis, additional, Eker, Hasan H., additional, van der Hoeven, Joost A.B., additional, van Heek, N. Tjarda, additional, Torrenga, Hans, additional, Bosscha, Koop, additional, Vermaas, Maarten, additional, Consten, Esther C.J., additional, and Oosterling, Steven J., additional

Published
2021
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24. Validation of the Aldosteronoma Resolution Score Within Current Clinical Practice

Author

Vorselaars, Wessel M. C. M., van Beek, Dirk-Jan, Postma, Emily L., Spiering, Wilko, Rinkes, Inne H. M. Borel, Valk, Gerlof D., Vriens, Menno R., Zarnegar, Rasa, Fahey, Thomas J., Drake, Frederick T., Duh, Quan Y., Talutis, Stephanie D., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Aranas, Minerva A. Romero, Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Sidhu, Stan B., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Engelsman, Els J. M. Anton F., van Dijkum, Nieveen, Metman, Madelon J. H., Kruijff, Schelto, Guided Treatment in Optimal Selected Cancer Patients (GUTS), Surgery, MUMC+: MA Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, CCA - Cancer Treatment and quality of life, APH - Quality of Care, APH - Global Health, and ACS - Microcirculation

Subjects
Adult, Male, medicine.medical_specialty, medicine.medical_treatment, ADRENALECTOMY, 030230 surgery, Body Mass Index, UNILATERAL PRIMARY ALDOSTERONISM, 03 medical and health sciences, 0302 clinical medicine, Primary aldosteronism, Internal medicine, HYPERALDOSTERONISM, Journal Article, medicine, Humans, CARDIOVASCULAR EVENTS, Antihypertensive Agents, Retrospective Studies, OUTCOMES, HYPERTENSION, business.industry, Adrenalectomy, Area under the curve, Retrospective cohort study, Vascular surgery, Middle Aged, medicine.disease, Prognosis, TRENDS, Adrenal Cortex Neoplasms, PREVALENCE, Cardiothoracic surgery, 030220 oncology & carcinogenesis, Area Under Curve, Cohort, Adrenocortical Adenoma, Surgery, Female, business, Body mass index
Abstract

Introduction: Complete resolution of hypertension after adrenalectomy for primary aldosteronism is far from a certainty. This stresses the importance of adequate preoperative patient counseling. The aldosteronoma resolution score (ARS) is a simple and easy to use prediction model only including four variables: ≤ 2 antihypertensive medications, body mass index ≤ 25 kg/m2, duration of hypertension ≤ 6 years and female sex. However, because the model was developed and validated within the USA over a decade ago, the applicability in modern practice and outside of the USA is questionable. Therefore, we aimed to validate the ARS in current clinical practice within an international cohort. Materials and method: Patients who underwent unilateral adrenalectomy, between 2010 and 2016, in 16 medical centers from the USA, Europe (EU), Canada (CA) and Australia (AU) were included. Resolution of hypertension was defined as normotension without antihypertensive medications. Results: In total, 514 patients underwent adrenalectomy and 435 (85%) patients were eligible. Resolution of hypertension was achieved in 27% patients within the total cohort and in 22%, 30%, 40% and 38% of patients within USA, EU, CA and AU, respectively (p = 0.015). The area under the curve (AUC) for the complete cohort was 0.751. Geographic validation displayed a AUC within the USA, EU, CA and AU of 0.782, 0.681, 0.811 and 0.667, respectively. Discussion: The ARS is an easy to use prediction model with a moderate to good predictive performance within current clinical practice. The model showed the highest predictive performance within North America but potentially has less predictive performance in EU and AU.

Published
2019
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25. Short-term postoperative outcomes after liver resection in the elderly patient: a nationwide population-based study

Author

Elfrink, Arthur K.E., primary, Kok, Niels F.M., additional, den Dulk, Marcel, additional, Buis, Carlijn I., additional, Kazemier, Geert, additional, Ijzermans, Jan N.M., additional, Lam, Hwai-Ding, additional, Hagendoorn, Jeroen, additional, van den Boezem, Peter B., additional, Ayez, Ninos, additional, Zonderhuis, Babs M., additional, Lips, Daan J., additional, Leclercq, Wouter K.G., additional, Kuhlmann, Koert F.D., additional, Marsman, Hendrik A., additional, Verhoef, Cornelis, additional, Patijn, Gijs A., additional, Grünhagen, Dirk J., additional, Klaase, Joost M., additional, Eker, Hasan H., additional, Belt, Eric T.J., additional, van Heek, N.Tjarda, additional, Torrenga, Hans, additional, Bosscha, Koop, additional, Doornebosch, Pascal, additional, Consten, Esther C.J., additional, Oosterling, Steven J., additional, de Boer, Marieke T., additional, Besselink, Marc G.H., additional, Dejong, Cornelis H.C., additional, te Riele, Wouter W., additional, Hoogwater, Frederik J.H., additional, Liem, Mike S.L., additional, Molenaar, I.Quintus, additional, Swijnenburg, Rutger-Jan, additional, and Braat, Andries E., additional

Published
2021
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28. Hospital variation in combined liver resection and thermal ablation for colorectal liver metastases and impact on short-term postoperative outcomes: a nationwide population-based study

Author

Elfrink, Arthur K.E., primary, Nieuwenhuizen, Sanne, additional, van den Tol, M. Petrousjka, additional, Burgmans, Mark C., additional, Prevoo, Warner, additional, Coolsen, Marielle M.E., additional, van den Boezem, Peter B., additional, van Delden, Otto M., additional, Hagendoorn, Jeroen, additional, Patijn, Gijs A., additional, Leclercq, Wouter K.G., additional, Liem, Mike S.L., additional, Rijken, Arjen M., additional, Verhoef, Cornelis, additional, Kuhlmann, Koert F.D., additional, Ruiter, Simeon J.S., additional, Grünhagen, Dirk J., additional, Klaase, Joost M., additional, Kok, Niels F.M., additional, Meijerink, Martijn R., additional, Swijnenburg, Rutger-Jan, additional, te Riele, Wouter W., additional, de Boer, Marieke T., additional, Dejong, Cees H.C., additional, van Gulik, Thomas H., additional, Hoogwater, Frederik J.H., additional, Molenaar, I.Q., additional, van der Leij, Christiaan, additional, Moelker, Adriaan, additional, Besselink, Marc G.H., additional, Buis, Carlijn I., additional, den Dulk, Marcel, additional, Bosscha, Koop, additional, Belt, Eric J.Th., additional, Vermaas, Maarten, additional, van Heek, Tjarda N.T., additional, Oosterling, Steven J., additional, Torrenga, Hans, additional, Eker, Hasan H., additional, and Consten, Esther C.J., additional

Published
2021
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29. A simplified primary aldosteronism surgical outcome score is a useful prediction model when target organ damage is unknown – Retrospective cohort study

Author

Suurd, Diederik P.D., primary, Visscher, Wouter P., additional, Vorselaars, Wessel M.C.M., additional, van Beek, Dirk-Jan, additional, Spiering, Wilko, additional, Borel Rinkes, Inne H.M., additional, Valk, Gerlof D., additional, Vriens, Menno R., additional, Zarnegar, Rasa, additional, Fahey, Thomas J., additional, Duh, Quan Y., additional, Shen, Wen T., additional, Drake, Frederick T., additional, McAneny, David B., additional, McManus, Catherine, additional, Lee, James A., additional, Grant, Scott B., additional, Grogan, Raymon H., additional, Romero Arenas, Minerva A., additional, Perrier, Nancy D., additional, Sturgeon, Cord, additional, Castelino, Tanya, additional, Mitmaker, Elliot J., additional, Parente, David N., additional, Pasternak, Jesse D., additional, Sidhu, Stan B., additional, Sywak, Mark, additional, D'Amato, Gerardo, additional, Raffaelli, Marco, additional, Schuermans, Valerie, additional, Bouvy, Nicole D., additional, Eker, Hasan H., additional, Bonjer, Jaap H., additional, Engelsman, Anton F., additional, van Dijkum, Els J.M. Nieveen, additional, Kerstens, Michiel N., additional, and Kruijff, Schelto, additional

Published
2021
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30. Case-mix adjustment to compare nationwide hospital performances after resection of colorectal liver metastases

Author

Elfrink, Arthur K E, van Zwet, Erik W, Swijnenburg, Rutger-Jan, den Dulk, Marcel, van den Boezem, Peter B, Mieog, J Sven D, Te Riele, Wouter W, Patijn, Gijs A, Leclercq, Wouter K G, Lips, Daan J, Rijken, Arjen M, Verhoef, Cornelis, Kuhlmann, Koert F D, Buis, Carlijn I, Bosscha, Koop, Belt, Eric J T, Vermaas, Maarten, van Heek, N Tjarda, Oosterling, Steven J, Torrenga, Hans, Eker, Hasan H, Consten, Esther C J, Marsman, Hendrik A, Wouters, Michel W J M, Kok, Niels F M, Grünhagen, Dirk J, Klaase, Joost M, Elfrink, Arthur K E, van Zwet, Erik W, Swijnenburg, Rutger-Jan, den Dulk, Marcel, van den Boezem, Peter B, Mieog, J Sven D, Te Riele, Wouter W, Patijn, Gijs A, Leclercq, Wouter K G, Lips, Daan J, Rijken, Arjen M, Verhoef, Cornelis, Kuhlmann, Koert F D, Buis, Carlijn I, Bosscha, Koop, Belt, Eric J T, Vermaas, Maarten, van Heek, N Tjarda, Oosterling, Steven J, Torrenga, Hans, Eker, Hasan H, Consten, Esther C J, Marsman, Hendrik A, Wouters, Michel W J M, Kok, Niels F M, Grünhagen, Dirk J, and Klaase, Joost M

Abstract

BACKGROUND: Differences in patient demographics and disease burden can influence comparison of hospital performances. This study aimed to provide a case-mix model to compare short-term postoperative outcomes for patients undergoing liver resection for colorectal liver metastases (CRLM).METHODS: This retrospective, population-based study included all patients who underwent liver resection for CRLM between 2014 and 2018 in the Netherlands. Variation in case-mix variables between hospitals and influence on postoperative outcomes was assessed using multivariable logistic regression. Primary outcomes were 30-day major morbidity and 30-day mortality. Validation of results was performed on the data from 2019.RESULTS: In total, 4639 patients were included in 28 hospitals. Major morbidity was 6.2% and mortality was 1.4%. Uncorrected major morbidity ranged from 3.3% to 13.7% and mortality ranged from 0.0% to 5.0%. between hospitals. Significant differences between hospitals were observed for age higher than 80 (0.0%-17.1%, p < 0.001), ASA 3 or higher (3.3%-36.3%, p < 0.001), histopathological parenchymal liver disease (0.0%-47.1%, p < 0.001), history of liver resection (8.1%-36.3%, p < 0.001), major liver resection (6.7%-38.0%, p < 0.001) and synchronous metastases (35.5%-62.1%, p < 0.001). Expected 30-day major morbidity between hospitals ranged from 6.4% to 11.9% and expected 30-day mortality ranged from 0.6% to 2.9%. After case-mix correction no significant outliers concerning major morbidity and mortality remained. Validation on patients who underwent liver resection for CRLM in 2019 affirmed these outcomes.CONCLUSION: Case-mix adjustment is a prerequisite to allow for institutional comparison of short-term postoperative outcomes after liver resection for CRLM.

Published
2021

31. 18F-Fludeoxyglucose-Positron Emission Tomography/Computed Tomography and Laparoscopy for Staging of Locally Advanced Gastric Cancer: A Multicenter Prospective Dutch Cohort Study (PLASTIC)

Author

Verpleegafd Vaatchirurgie D4 Oost, MS CGO, Cancer, MS Radiologie, MS Medische Oncologie, HEE, Child Health, JC onderzoeksprogramma Methodologie, Gertsen, Emma C., Brenkman, Hylke J.F., Van Hillegersberg, Richard, Van Sandick, Johanna W., Van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., Luyer, Misha D.P., Nieuwenhuijzen, Grard A.P., Van Lanschot, Jan J.B., Lagarde, Sjoerd M., Wijnhoven, Bas P.L., De Steur, Wobbe O., Hartgrink, Henk H., Stoot, Jan H.M.B., Hulsewe, Karel W.E., Spillenaar Bilgen, Ernst J., Van Det, Marc J., Kouwenhoven, Ewout A., Van Der Peet, Donald L., Daams, Freek, Van Grieken, Nicole C.T., Heisterkamp, Joos, Van Etten, Boudewijn, Van Den Berg, Jan Willem, Pierie, Jean Pierre, Eker, Hasan H., Thijssen, Annemieke Y., Belt, Eric J.T., Van Duijvendijk, Peter, Wassenaar, Eelco, Van Laarhoven, Hanneke W.M., Wevers, Kevin P., Hol, Lieke, Wessels, Frank J., Haj Mohammad, Nadia, Van Der Meulen, Miriam P., Frederix, Geert W.J., Vegt, Erik, Siersema, Peter D., Ruurda, Jelle P., Verpleegafd Vaatchirurgie D4 Oost, MS CGO, Cancer, MS Radiologie, MS Medische Oncologie, HEE, Child Health, JC onderzoeksprogramma Methodologie, Gertsen, Emma C., Brenkman, Hylke J.F., Van Hillegersberg, Richard, Van Sandick, Johanna W., Van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., Luyer, Misha D.P., Nieuwenhuijzen, Grard A.P., Van Lanschot, Jan J.B., Lagarde, Sjoerd M., Wijnhoven, Bas P.L., De Steur, Wobbe O., Hartgrink, Henk H., Stoot, Jan H.M.B., Hulsewe, Karel W.E., Spillenaar Bilgen, Ernst J., Van Det, Marc J., Kouwenhoven, Ewout A., Van Der Peet, Donald L., Daams, Freek, Van Grieken, Nicole C.T., Heisterkamp, Joos, Van Etten, Boudewijn, Van Den Berg, Jan Willem, Pierie, Jean Pierre, Eker, Hasan H., Thijssen, Annemieke Y., Belt, Eric J.T., Van Duijvendijk, Peter, Wassenaar, Eelco, Van Laarhoven, Hanneke W.M., Wevers, Kevin P., Hol, Lieke, Wessels, Frank J., Haj Mohammad, Nadia, Van Der Meulen, Miriam P., Frederix, Geert W.J., Vegt, Erik, Siersema, Peter D., and Ruurda, Jelle P.

Published
2021

32. Case-mix adjustment to compare nationwide hospital performances after resection of colorectal liver metastases

Author

Elfrink, Arthur K.E., primary, van Zwet, Erik W., additional, Swijnenburg, Rutger-Jan, additional, den Dulk, Marcel, additional, van den Boezem, Peter B., additional, Mieog, J. Sven D., additional, te Riele, Wouter W., additional, Patijn, Gijs A., additional, Leclercq, Wouter K.G., additional, Lips, Daan J., additional, Rijken, Arjen M., additional, Verhoef, Cornelis, additional, Kuhlmann, Koert F.D., additional, Buis, Carlijn I., additional, Bosscha, Koop, additional, Belt, Eric J.T., additional, Vermaas, Maarten, additional, van Heek, N. Tjarda, additional, Oosterling, Steven J., additional, Torrenga, Hans, additional, Eker, Hasan H., additional, Consten, Esther C.J., additional, Marsman, Hendrik A., additional, Wouters, Michel W.J.M., additional, Kok, Niels F.M., additional, Grünhagen, Dirk J., additional, Klaase, Joost M., additional, Besselink, Marc G.H., additional, de Boer, Marieke T., additional, Dejong, Cees H.C., additional, van Gulik, Thomas M., additional, Hagendoorn, Jeroen, additional, Hoogwater, Frederik H.J., additional, Molenaar, I. Quintus, additional, and Liem, Mike S.L., additional

Published
2021
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35. Population-based study on practice variation regarding preoperative systemic chemotherapy in patients with colorectal liver metastases and impact on short-term outcomes

Author

Elfrink, Arthur K.E., primary, Kok, Niels F.M., additional, van der Werf, Leonie R., additional, Krul, Myrtle F., additional, Marra, Elske, additional, Wouters, Michel W.J.M., additional, Verhoef, Cornelis, additional, Kuhlmann, Koert F.D., additional, den Dulk, Marcel, additional, Swijnenburg, Rutger-Jan, additional, te Riele, Wouter W., additional, van den Boezem, Peter B., additional, Leclercq, Wouter K.G., additional, Lips, Daan J., additional, Nieuwenhuijs, Vincent B., additional, Gobardhan, Paul D., additional, Hartgrink, Henk H., additional, Buis, Carlijn I., additional, Grünhagen, Dirk J., additional, Klaase, Joost M., additional, de Boer, Marieke T., additional, Besselink, Marc G.H., additional, Dejong, Cees H.C., additional, van Gulik, Thomas H., additional, Hagendoorn, Jeroen, additional, Hoogwater, Frederik J.H., additional, Liem, Mike S.L., additional, Molenaar, I. Quintus, additional, Patijn, Gijs A., additional, Bosscha, Koop, additional, Belt, Eric J.Th, additional, Vermaas, Maarten, additional, Gerhards, Michael F., additional, van Heek, N.T., additional, Oosterling, Steven J., additional, Torrenga, Hans, additional, Eker, Hasan H., additional, Consten, Esther C.J., additional, and van Duijvendijk, Peter, additional

Published
2020
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36. Resectability and Ablatability Criteria for the Treatment of Liver Only Colorectal Metastases: Multidisciplinary Consensus Document from the COLLISION Trial Group

Author

Nieuwenhuizen, Sanne, primary, Puijk, Robbert S., additional, van den Bemd, Bente, additional, Aldrighetti, Luca, additional, Arntz, Mark, additional, van den Boezem, Peter B., additional, Bruynzeel, Anna M. E., additional, Burgmans, Mark C., additional, de Cobelli, Francesco, additional, Coolsen, Marielle M. E., additional, Dejong, Cornelis H. C., additional, Derks, Sarah, additional, Diederik, Arjen, additional, van Duijvendijk, Peter, additional, Eker, Hasan H., additional, Engelsman, Anton F., additional, Erdmann, Joris I., additional, Fütterer, Jurgen J., additional, Geboers, Bart, additional, Groot, Gerie, additional, Haasbeek, Cornelis J. A., additional, Janssen, Jan-Jaap, additional, de Jong, Koert P., additional, Kater, G. Matthijs, additional, Kazemier, Geert, additional, Kruimer, Johan W. H., additional, Leclercq, Wouter K. G., additional, van der Leij, Christiaan, additional, Manusama, Eric R., additional, Meier, Mark A. J., additional, van der Meijs, Bram B., additional, Melenhorst, Marleen C. A. M., additional, Nielsen, Karin, additional, Nijkamp, Maarten W., additional, Potters, Fons H., additional, Prevoo, Warner, additional, Rietema, Floris J., additional, Ruarus, Alette H., additional, Ruiter, Simeon J. S., additional, Schouten, Evelien A. C., additional, Serafino, Gian Piero, additional, Sietses, Colin, additional, Swijnenburg, Rutger-Jan, additional, Timmer, Florentine E. F., additional, Versteeg, Kathelijn S., additional, Vink, Ted, additional, de Vries, Jan J. J., additional, de Wilt, Johannes H. W., additional, Zonderhuis, Barbara M., additional, Scheffer, Hester J., additional, van den Tol, Petrousjka M. P., additional, and Meijerink, Martijn R., additional

Published
2020
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37. Clinical outcomes after surgery for primary aldosteronism: Evaluation of the PASO-investigators’ consensus criteria within a worldwide cohort of patients

Author

Vorselaars, Wessel M.C.M., primary, van Beek, Dirk-Jan, additional, Postma, Emily L., additional, Spiering, Wilko, additional, Borel Rinkes, Inne H.M., additional, Valk, Gerlof D., additional, Vriens, Menno R., additional, Zarnegar, Rasa, additional, Drake, Frederick T., additional, Duh, Quan Y., additional, Talutis, Stephanie D., additional, McAneny, David B., additional, McManus, Catherine, additional, Lee, James A., additional, Grant, Scott B., additional, Grogan, Raymon H., additional, Romero Arenas, Minerva A., additional, Perrier, Nancy D., additional, Peipert, Benjamin J., additional, Mongelli, Michael N., additional, Castelino, Tanya, additional, Mitmaker, Elliot J., additional, Parente, David N., additional, Pasternak, Jesse D., additional, Engelsman, Anton F., additional, Sywak, Mark, additional, D’Amato, Gerardo, additional, Raffaelli, Marco, additional, Schuermans, Valerie, additional, Bouvy, Nicole D., additional, Eker, Hasan H., additional, Bonjer, H. Jaap, additional, Vaarzon Morel, Nina M., additional, Nieveen van Dijkum, Els J.M., additional, Metman, Madelon J.H., additional, and Kruijff, Schelto, additional

Published
2019
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38. Clinical outcomes after surgery for primary aldosteronism : Evaluation of the PASO-investigators’ consensus criteria within a worldwide cohort of patients

Author

Vorselaars, Wessel M.C.M., van Beek, Dirk Jan, Postma, Emily L., Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., Vriens, Menno R., Zarnegar, Rasa, Drake, Frederick T., Duh, Quan Y., Talutis, Stephanie D., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, Nina M., Nieveen van Dijkum, Els J.M., Metman, Madelon J.H., Kruijff, Schelto, Vorselaars, Wessel M.C.M., van Beek, Dirk Jan, Postma, Emily L., Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., Vriens, Menno R., Zarnegar, Rasa, Drake, Frederick T., Duh, Quan Y., Talutis, Stephanie D., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, Nina M., Nieveen van Dijkum, Els J.M., Metman, Madelon J.H., and Kruijff, Schelto

Published
2019

39. Clinical outcomes after surgery for primary aldosteronism: Evaluation of the PASO-investigators’ consensus criteria within a worldwide cohort of patients

Author

MS CGO, Other research (not in main researchprogram), Heelkunde Opleiding, MS Interne Geneeskunde, Circulatory Health, Regenerative Medicine and Stem Cells, Cancer, MS Endocriene Oncologie, Vorselaars, Wessel M.C.M., van Beek, Dirk Jan, Postma, Emily L., Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., Vriens, Menno R., Zarnegar, Rasa, Drake, Frederick T., Duh, Quan Y., Talutis, Stephanie D., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, Nina M., Nieveen van Dijkum, Els J.M., Metman, Madelon J.H., Kruijff, Schelto, MS CGO, Other research (not in main researchprogram), Heelkunde Opleiding, MS Interne Geneeskunde, Circulatory Health, Regenerative Medicine and Stem Cells, Cancer, MS Endocriene Oncologie, Vorselaars, Wessel M.C.M., van Beek, Dirk Jan, Postma, Emily L., Spiering, Wilko, Borel Rinkes, Inne H.M., Valk, Gerlof D., Vriens, Menno R., Zarnegar, Rasa, Drake, Frederick T., Duh, Quan Y., Talutis, Stephanie D., McAneny, David B., McManus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, Nina M., Nieveen van Dijkum, Els J.M., Metman, Madelon J.H., and Kruijff, Schelto

Published
2019

40. Clinical Outcomes after Unilateral Adrenalectomy for Primary Aldosteronism

Author

Vorselaars, Wessel M. C. M., Nell, Sjoerd, Postma, Emily L., Zarnegar, Rasa, Drake, F. Thurston, Duh, Quan-Yang, Talutis, Stephanie D., Mcaneny, David B., Mcmanus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, N. M., Nieveen Van Dijkum, Els J. M., Vrielink, Otis M., Kruijff, Schelto, Spiering, Wilko, Borel Rinkes, Inne H. M., Valk, Gerlof D., Vriens, Menno R., Raffaelli, Marco (ORCID:0000-0002-1259-2491), Vorselaars, Wessel M. C. M., Nell, Sjoerd, Postma, Emily L., Zarnegar, Rasa, Drake, F. Thurston, Duh, Quan-Yang, Talutis, Stephanie D., Mcaneny, David B., Mcmanus, Catherine, Lee, James A., Grant, Scott B., Grogan, Raymon H., Romero Arenas, Minerva A., Perrier, Nancy D., Peipert, Benjamin J., Mongelli, Michael N., Castelino, Tanya, Mitmaker, Elliot J., Parente, David N., Pasternak, Jesse D., Engelsman, Anton F., Sywak, Mark, D'Amato, Gerardo, Raffaelli, Marco, Schuermans, Valerie, Bouvy, Nicole D., Eker, Hasan H., Bonjer, H. Jaap, Vaarzon Morel, N. M., Nieveen Van Dijkum, Els J. M., Vrielink, Otis M., Kruijff, Schelto, Spiering, Wilko, Borel Rinkes, Inne H. M., Valk, Gerlof D., Vriens, Menno R., and Raffaelli, Marco (ORCID:0000-0002-1259-2491)

Abstract

Importance: In addition to biochemical cure, clinical benefits after surgery for primary aldosteronism depend on the magnitude of decrease in blood pressure (BP) and use of antihypertensive medications with a subsequent decreased risk of cardiovascular and/or cerebrovascular morbidity and drug-induced adverse effects. Objective: To evaluate the change in BP and use of antihypertensive medications within an international cohort of patients who recently underwent surgery for primary aldosteronism. Design, Setting, and Participants: A cohort study was conducted across 16 referral medical centers in Europe, the United States, Canada, and Australia. Patients who underwent unilateral adrenalectomy for primary aldosteronism between January 2010 and December 2016 were included. Data analysis was performed from August 2017 to June 2018. Unilateral disease was confirmed using computed tomography, magnetic resonance imaging, and/or adrenal venous sampling. Patients with missing or incomplete preoperative or follow-up data regarding BP or corresponding number of antihypertensive medications were excluded. Main Outcomes and Measures: Clinical success was defined based on postoperative BP and number of antihypertensive medications. Cure was defined as normotension without antihypertensive medications, and clear improvement as normotension with lower or equal use of antihypertensive medications. In patients with preoperative normotensivity, improvement was defined as postoperative normotension with lower antihypertensive use. All other patients were stratified as no clear success because the benefits of surgery were less obvious, mainly owing to postoperative, persistent hypertension. Clinical outcomes were assessed at follow-up closest to 6 months after surgery. Results: On the basis of inclusion and exclusion criteria, a total of 435 patients (84.6%) from a cohort of 514 patients who underwent unilateral adrenalectomy were eligible. Of these patients, 186 (42.3%) were women; mea

Published
2019

41. Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial

Author

Jairam, An P, primary, Timmermans, Lucas, additional, Eker, Hasan H, additional, Pierik, Robert E G J M, additional, van Klaveren, David, additional, Steyerberg, Ewout W, additional, Timman, Reinier, additional, van der Ham, Arie C, additional, Dawson, Imro, additional, Charbon, Jan A, additional, Schuhmacher, Christoph, additional, Mihaljevic, André, additional, Izbicki, Jakob R, additional, Fikatas, Panagiotis, additional, Knebel, Philip, additional, Fortelny, René H, additional, Kleinrensink, Gert-Jan, additional, Lange, Johan F, additional, Jeekel, Hans J, additional, Nieuwenhuizen, Jeroen, additional, Hop, Wim C J, additional, Burger, Pim C W, additional, Verhagen, Hence J, additional, Klitsie, Pieter J, additional, van de Berg, Michiel, additional, and Golling, Markus, additional

Published
2017
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42. Diagnosis and management of acute appendicitis : EAES consensus development conference 2015

Author

Gorter, Ramon R., Eker, Hasan H., Gorter-Stam, Marguerite A. W., Abis, Gabor S. A., Acharya, Amish, Ankersmit, Marjolein, Antoniou, Stavros Athanasios, Arolfo, Simone, Babic, Benjamin, Boni, Luigi, Bruntink, Marlieke, Dam, Dieuwertje A. van, Defoort, Barbara, Deijen, Charlotte L., DeLacy, F. Borja, Go, Peter M. N. Y. H., Harmsen, Annelieke M. K., Helder, Rick S. van den, Iordache, Florin, Ket, Johannes C. F., Muysoms, Filip E., Ozmen, M. Mahir, Papoulas, Michail, Rhodes, Michael, Straatman, Jennifer, Tenhagen, Mark, Turrado, Victor, Vereczkei, Andras, Vilallonga, Ramon, Deelder, Jort D., Bonjer, Jaap, Gorter, Ramon R., Eker, Hasan H., Gorter-Stam, Marguerite A. W., Abis, Gabor S. A., Acharya, Amish, Ankersmit, Marjolein, Antoniou, Stavros Athanasios, Arolfo, Simone, Babic, Benjamin, Boni, Luigi, Bruntink, Marlieke, Dam, Dieuwertje A. van, Defoort, Barbara, Deijen, Charlotte L., DeLacy, F. Borja, Go, Peter M. N. Y. H., Harmsen, Annelieke M. K., Helder, Rick S. van den, Iordache, Florin, Ket, Johannes C. F., Muysoms, Filip E., Ozmen, M. Mahir, Papoulas, Michail, Rhodes, Michael, Straatman, Jennifer, Tenhagen, Mark, Turrado, Victor, Vereczkei, Andras, Vilallonga, Ramon, Deelder, Jort D., and Bonjer, Jaap

Abstract

Unequivocal international guidelines regarding the diagnosis and management of patients with acute appendicitis are lacking. The aim of the consensus meeting 2015 of the EAES was to generate a European guideline based on best available evidence and expert opinions of a panel of EAES members. After a systematic review of the literature by an international group of surgical research fellows, an expert panel with extensive clinical experience in the management of appendicitis discussed statements and recommendations. Statements and recommendations with more than 70 % agreement by the experts were selected for a web survey and the consensus meeting of the EAES in Bucharest in June 2015. EAES members and attendees at the EAES meeting in Bucharest could vote on these statements and recommendations. In the case of more than 70 % agreement, the statement or recommendation was defined as supported by the scientific community. Results from both the web survey and the consensus meeting in Bucharest are presented as percentages. In total, 46 statements and recommendations were selected for the web survey and consensus meeting. More than 232 members and attendees voted on them. In 41 of 46 statements and recommendations, more than 70 % agreement was reached. All 46 statements and recommendations are presented in this paper. They comprise topics regarding the diagnostic work-up, treatment indications, procedural aspects and post-operative care. The consensus meeting produced 46 statements and recommendations on the diagnostic work-up and management of appendicitis. The majority of the EAES members supported these statements. These consensus proceedings provide additional guidance to surgeons and surgical residents providing care to patients with appendicitis.

Published
2017

43. Short-term Results of a Randomized Controlled Trial Comparing Primary Suture With Primary Glued Mesh Augmentation to Prevent Incisional Hernia

Author

Timmermans, Lucas, primary, Eker, Hasan H., additional, Steyerberg, Ewout W., additional, Jairam, An, additional, de Jong, Diederik, additional, Pierik, E. G. J. M., additional, Lases, S. S., additional, van der Ham, Arie C., additional, Dawson, Imro, additional, Charbon, Jan, additional, Schuhmacher, Christoph, additional, Izbicki, Jakob R., additional, Neuhaus, Peter, additional, Knebel, Peter, additional, Fortelny, Rene, additional, Kleinrensink, Gert-Jan, additional, Jeekel, Johannes, additional, and Lange, Johan F., additional

Published
2015
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48. Incisional hernia after liver transplantation: risk factors and health-related quality of life.

Author

Goede, Barry, Eker, Hasan H., Klitsie, Pieter J., Kempen, Bob J.H., Polak, Wojtek G., Hop, Wim C.J., Metselaar, Herold J., Tilanus, Hugo W., Lange, Johan F., and Kazemier, Geert

Subjects
*HERNIA, *LIVER transplantation, *QUALITY of life, *CROSS-sectional method, *FOLLOW-up studies (Medicine), *INTENSIVE care units, *EPIDEMIOLOGY
Abstract

The aim of this cross-sectional study was to analyze the incidence of incisional hernia after liver transplantation ( LT), to determine potential risk factors for their development, and to assess their impact on health-related quality of life ( HRQoL). Patients who underwent LT through a J-shaped incision with a minimum follow-up of three months were included. Follow-up was conducted at the outpatient clinic. Short Form 36 ( SF-36) and body image questionnaire ( BIQ) were used for the assessment of HRQoL. A total of 140 patients was evaluated. The mean follow-up period was 33 ( SD 20) months. Sixty patients (43%) were diagnosed with an incisional hernia. Multivariate analysis revealed surgical site infection ( OR 5.27, p = 0.001), advanced age ( OR 1.05, p = 0.003), and prolonged ICU stay ( OR 1.54, p = 0.022) to be independent risk factors for development of incisional hernia after LT. Patients with an incisional hernia experienced significantly diminished HRQoL with respect to physical, social, and mental aspects. In conclusion, patients who undergo LT exhibit a high incidence of incisional hernia, which has a considerable impact on HRQoL. Development of incisional hernia was shown to be related to surgical site infection, advanced age, and prolonged ICU stay. [ABSTRACT FROM AUTHOR]

Published
2014
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49. A double blind randomized controlled trial comparing primary suture closure with mesh augmented closure to reduce incisional hernia incidence.

Author

Nieuwenhuizen, Jeroen, Eker, Hasan H., Timmermans, Lucas, Hop, Wim C. J., Kleinrensink, Gert-Jan, Jeekel, Johannes, and Lange, Johan F.

Subjects
RANDOMIZED controlled trials, HERNIA, ABDOMINAL surgery, SURGICAL complications, ABDOMINAL aorta, AORTIC aneurysms, OVERWEIGHT persons, DISEASES
Abstract

Background Incisional hernia is the most frequently seen long term complication after laparotomy causing much morbidity and even mortality. The overall incidence remains 11-20%, despite studies attempting to optimize closing techniques. Two patient groups, patients with abdominal aortic aneurysm and obese patients, have a risk for incisional hernia after laparotomy of more than 30%. These patients might benefit from mesh augmented midline closure as a means to reduce incisional hernia incidence. Methods/design The PRImary Mesh Closure of Abdominal Midline Wound (PRIMA) trial is a doubleblinded international multicenter randomized controlled trial comparing running slowly absorbable suture closure with the same closure augmented with a sublay or onlay mesh. Primary endpoint will be incisional hernia incidence 2 years postoperatively. Secondary outcomes will be postoperative complications, pain, quality of life and cost effectiveness. A total of 460 patients will be included in three arms of the study and randomized between running suture closure, onlay mesh closure or sublay mesh closure. Follow-up will be at 1, 3, 12 and 24 months with ultrasound imaging performed at 6 and 24 months to objectify the presence of incisional hernia. Patients, investigators and radiologists will be blinded throughout the whole follow up. Disccusion The use of prosthetic mesh has proven effective and safe in incisional hernia surgery however its use in a prophylactic manner has yet to be properly investgated. The PRIMA trial will provide level 1b evidence whether mesh augmented midline abdominal closure reduces incisional hernia incidence in high risk groups. [ABSTRACT FROM AUTHOR]

Published
2013
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50. 18F-Fludeoxyglucose–Positron Emission Tomography/Computed Tomography and Laparoscopy for Staging of Locally Advanced Gastric Cancer: A Multicenter Prospective Dutch Cohort Study (PLASTIC)

Author

Gertsen, Emma C., Brenkman, Hylke J. F., van Hillegersberg, Richard, van Sandick, Johanna W., van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., Luyer, Misha D. P., Nieuwenhuijzen, Grard A. P., van Lanschot, Jan J. B., Lagarde, Sjoerd M., Wijnhoven, Bas P. L., de Steur, Wobbe O., Hartgrink, Henk H., Stoot, Jan H. M. B., Hulsewe, Karel W. E., Spillenaar Bilgen, Ernst J., van Det, Marc J., Kouwenhoven, Ewout A., van der Peet, Donald L., Daams, Freek, van Grieken, Nicole C. T., Heisterkamp, Joos, van Etten, Boudewijn, van den Berg, Jan Willem, Pierie, Jean Pierre, Eker, Hasan H., Thijssen, Annemieke Y., Belt, Eric J. T., van Duijvendijk, Peter, Wassenaar, Eelco, van Laarhoven, Hanneke W. M., Wevers, Kevin P., Hol, Lieke, Wessels, Frank J., Haj Mohammad, Nadia, van der Meulen, Miriam P., Frederix, Geert W. J., Vegt, Erik, Siersema, Peter D., and Ruurda, Jelle P.

Abstract

IMPORTANCE: The optimal staging for gastric cancer remains a matter of debate. OBJECTIVE: To evaluate the value of 18F-fludeoxyglucose–positron emission tomography with computed tomography (FDG-PET/CT) and staging laparoscopy (SL) in addition to initial staging by means of gastroscopy and CT in patients with locally advanced gastric cancer. DESIGN, SETTING, AND PARTICIPANTS: This multicenter prospective, observational cohort study included 394 patients with locally advanced, clinically curable gastric adenocarcinoma (≥cT3 and/or N+, M0 category based on CT) between August 1, 2017, and February 1, 2020. EXPOSURES: All patients underwent an FDG-PET/CT and/or SL in addition to initial staging. MAIN OUTCOMES AND MEASURES: The primary outcome was the number of patients in whom the intent of treatment changed based on the results of these 2 investigations. Secondary outcomes included diagnostic performance, number of incidental findings on FDG-PET/CT, morbidity and mortality after SL, and diagnostic delay. RESULTS: Of the 394 patients included, 256 (65%) were men and mean (SD) age was 67.6 (10.7) years. A total of 382 patients underwent FDG-PET/CT and 357 underwent SL. Treatment intent changed from curative to palliative in 65 patients (16%) based on the additional FDG-PET/CT and SL findings. FDG-PET/CT detected distant metastases in 12 patients (3%), and SL detected peritoneal or locally nonresectable disease in 73 patients (19%), with an overlap of 7 patients (2%). FDG-PET/CT had a sensitivity of 33% (95% CI, 17%-53%) and specificity of 97% (95% CI, 94%-99%) in detecting distant metastases. Secondary findings on FDG/PET were found in 83 of 382 patients (22%), which led to additional examinations in 65 of 394 patients (16%). Staging laparoscopy resulted in a complication requiring reintervention in 3 patients (0.8%) without postoperative mortality. The mean (SD) diagnostic delay was 19 (14) days. CONCLUSIONS AND RELEVANCE: This study’s findings suggest an apparently limited additional value of FDG-PET/CT; however, SL added considerably to the staging process of locally advanced gastric cancer by detection of peritoneal and nonresectable disease. Therefore, it may be useful to include SL in guidelines for staging advanced gastric cancer, but not FDG-PET/CT.

Published
2021
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