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Aim. To analyze typical outpatient management approaches to type 2 diabetes mellitus (T2DM).Materials and Methods. We analyzed 211 files from 7 outpatient clinics, containing case records of patients, regularly examined during2009. VEN, ABC- and frequency analyses were conducted. Results. Prescription percentage for medications with proved prognosis improvement did not substantially differ from recommendedlevel. Main direct expenditures were related to antihyperglycemic, antihypertensive and hypolipidemic agents (class V). Inexpensivemedications without proven efficiency (class N) were prescribed more frequently than those with capacity to improve quality of life(class E). Testing for HbA1c level was found to be of inadequate frequency and thus complicated assessment of antihyperglycemic treatmentefficacy. Number of patients with improvement in arterial hypertension showed an increase, but treatment goals were not achievedin 2/3 of patients (according to office measurement). Prescription frequency of statins, though growing in the course of year, remainedinsufficient; rare testing for LDL complicated assessment of hypolipidemic treatment adequacy. Conclusion. Structure of pharmacological treatment is fairly adequate, but goals of multifactor therapy are not achieved in a significantpercentage of patients, which may be explained by peculiarities of diabetes pathogenesis, prescription of inadequate treatment regimensand doses and insufficient dynamic control.

Aim. To analyse factors hampering the achievement of compensation of carbohydrate metabolism in patients with type 2 diabetes mellitus treated for3 months with diabeton MB at a daily dose of 90-120 mg under real practical conditions. Materials and methods. This open study included 70 patients with type 2 diabetes mellitus given gliclazide MB-based hypoglycemic therapy(90-120 mg/day); their HbA1c level was measured before and 3 months after the onset of therapy. Results. The treatment resulted in a significant decrease of the HbA1c level especially pronounced in patients capable of following the rational therapeuticstrategy. At the closing visit, each patient was prescribed a pathogenetically sound regime of combined hypoglycemic therapy. Conclusion. Poor efficacy of hypoglycemic treatment in real clinical practice is attributable to frequent prescription of monotherapy, untimely onsetof insulin administration, its correction and intensification to meet changing requirements