41 results on '"Eisenhauer, Mary A."'
Search Results
2. Promoting Change Agency in Early Education
- Author
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Cahill, Mary Ann, primary, Eisenhauer, Mary Jane, additional, and Gregory, Anne E., additional
- Published
- 2022
- Full Text
- View/download PDF
3. Stemming the Opioid Crisis With Three-Year-Olds in Rural America
- Author
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Eisenhauer, Mary Jane, primary, Gregory, Anne E., additional, and Cahill, Mary Ann, additional
- Published
- 2020
- Full Text
- View/download PDF
4. Teachers, Nurses, and Families : Countdown to a Healthy Start
- Author
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Eisenhauer, Mary Jane and Schooley, Angela
- Published
- 2016
5. Differentiation between traumatic tap and aneurysmal subarachnoid hemorrhage : prospective cohort study
- Author
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Perry, Jeffrey J, Alyahya, Bader, Sivilotti, Marco L A, Bullard, Michael J, Émond, Marcel, Sutherland, Jane, Worster, Andrew, Hohl, Corinne, Lee, Jacques S, Eisenhauer, Mary A, Pauls, Merril, Lesiuk, Howard, Wells, George A, and Stiell, Ian G
- Published
- 2015
6. Capturing the Image of a Male Preschool Teacher
- Author
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Eisenhauer, Mary Jane and Pratt, David
- Abstract
In the United States, only 2.2 percent of preschool and kindergarten teachers and 5 percent of child care workers are men. Other countries have much higher rates, but the percentage of men in U.S. early education has remained between 2 and 3 percent for the last several years. There are many reasons why so few men become early childhood educators. Most often cited are the low salaries in the field, the long history of the profession being dominated by females, and the negative stigma sometimes associated with a man working with young children. This article describes how preservice teachers in an early childhood education methods course captured the image of a male preschool teacher by observing Mr. K, a pre-K teacher who teaches 3-year-olds at Northview Early Learning Center, an early childhood program within a large urban school corporation in Michigan City, Indiana. Providing a portrait of one male teacher is just one small step in helping others understand the potential for males to work in the early childhood environment.
- Published
- 2010
7. Dolls, Blocks, and Puzzles: Playing with Mathematical Understandings
- Author
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Eisenhauer, Mary Jane and Feikes, David
- Abstract
This article describes a learning experience designed for teachers of children in primary classrooms (K-3) who are taking graduate courses. The learning experience offers new insights into the different ways young children encounter math in their natural, playful environment. Through a hands-on workshop approach, the students engaged in firsthand experiences as active learners. This approach was based on the authors' work with the Connecting Mathematics for Elementary Teachers (CMET) project, which develops materials to help prospective teachers connect their learning of mathematics to how "children" understand and learn mathematics. CMET emphasizes mathematics from the child's perspective and directly relates it to the math content that will be taught to children. And what better way to explore how children learn mathematics than to return to children's earliest mathematical experiences with dolls, blocks, and puzzles.
- Published
- 2009
8. Factors influencing time to computed tomography in emergency department patients with suspected subarachnoid haemorrhage
- Author
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Khan, Maryam, Sivilotti, Marco L A, Bullard, Michael J, Émond, Marcel, Sutherland, Jane, Worster, Andrew, Hohl, Corinne M, Lee, Jacques S, Eisenhauer, Mary, Pauls, Merril, Lesiuk, Howard, Wells, George A, Stiell, Ian G, and Perry, Jeffrey J
- Published
- 2017
- Full Text
- View/download PDF
9. Sensitivity of computed tomography performed within six hours of onset of headache for diagnosis of subarachnoid haemorrhage: prospective cohort study
- Author
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Perry, Jeffrey J, Stiell, Ian G, Sivilotti, Marco L A, Bullard, Michael J, Émond, Marcel, Symington, Cheryl, Sutherland, Jane, Worster, Andrew, Hohl, Corinne, Lee, Jacques S, Eisenhauer, Mary A, Mortensen, Melodie, Mackey, Duncan, Pauls, Merril, Lesiuk, Howard, and Wells, George A
- Published
- 2011
10. High risk clinical characteristics for subarachnoid haemorrhage in patients with acute headache: prospective cohort study
- Author
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Perry, Jeffrey J, Stiell, Ian G, Sivilotti, Marco L A, Bullard, Michael J, Lee, Jacques S, Eisenhauer, Mary, Symington, Cheryl, Mortensen, Melodie, Sutherland, Jane, Lesiuk, Howard, and Wells, George A
- Published
- 2010
11. Implementation of the Canadian C-Spine Rule: prospective 12 centre cluster randomised trial
- Author
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Stiell, Ian G, Clement, Catherine M, Grimshaw, Jeremy, Brison, Robert J, Rowe, Brian H, Schull, Michael J, Lee, Jacques S, Brehaut, Jamie, McKnight, R Douglas, Eisenhauer, Mary A, Dreyer, Jonathan, Letovsky, Eric, Rutledge, Tim, MacPhail, Iain, Ross, Scott, Shah, Amit, Perry, Jeffrey J, Holroyd, Brian R, Ip, Urbain, Lesiuk, Howard, and Wells, George A
- Published
- 2009
12. Early Childhood Service-Learning Mentors: Promoting Student Leadership
- Author
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Eisenhauer, Mary Jane, primary
- Published
- 2015
- Full Text
- View/download PDF
13. Comparison of the Canadian CT Head Rule and the New Orleans Criteria in patients with minor head injury
- Author
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Stiell, Ian G., Schull, Michael J., Eisenhauer, Mary A., Holroyd, Brian, Reardon, Mark, Clement, Catherine M., Rowe, Brian H., McKnight, R. Douglas, Bandiera, Glen, Lee, Jacques S., Dreyer, Jonathan, Worthington, James R., Greenberg, Gary, Lesiuk, Howard, MacPhail, Iain, and Wells, George A.
- Subjects
Head injuries -- Diagnosis ,CT imaging -- Usage ,CT imaging -- Standards - Abstract
A study compares the clinical performance of the Canadian Computed Tomography (CT) Head Rule (CCHR) and the New Orleans Criteria (NOC) for detecting the need for neurosurgical intervention and clinically important brain injury. Results show that for patients with minor head injury and a Glasgow Coma Scale (GCS) score of 15, both decision rules have equivalent high sensitivities, but the CCHR has higher specificity for important outcomes and its use may result in reduced imaging rates.
- Published
- 2005
14. The Canadian C-Spine Rule versus the NEXUS Low-Risk Criteria in patients with trauma
- Author
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Stiell, Ian G., Clement, Catherine M., McKnight, R. Douglas, Brison, Robert, Schull, Michael J., Rowe, Brian H., Worthington, James R., Eisenhauer, Mary A., Cass, Daniel, Greenberg, Gary, MacPhail, Iain, Dreyer, Jonathan, Lee, Jacques S., Bandiera, Glen, Reardon, Mark, Holroyd, Brian, Lesiuk, Howard, and Wells, George A.
- Subjects
Diagnosis, Radioscopic ,Health status indicators -- Evaluation ,Neck -- Injuries - Abstract
The Canadian C-Spine Rule (CCR) is more accurate than the National Emergency X-Radiography Utilization Study (NEXUS) Low-Risk Criteria for identifying trauma patients who probably do not have an injured neck and therefore do not need a neck X-ray. This was the conclusion of a study of 8,283 patients. The CCR only missed one patient with a neck injury whereas the NEXUS criteria missed 16 patients with a neck injury. The CCR also reduced the number of neck X-rays that were done.
- Published
- 2003
15. Wrist and Forearm
- Author
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Woolfrey, Karen G.H., primary, Woolfrey, Michael R., additional, and Eisenhauer, Mary A., additional
- Published
- 2010
- Full Text
- View/download PDF
16. Contributors
- Author
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Aaron, Cynthia K., primary, Abbott, Jean T., additional, Abu-Laban, Riyad B., additional, Adams, Bruce D., additional, Adams, James G., additional, Adams, Stephen L., additional, Adirim, Terry A., additional, Alagappan, Kumar, additional, Amsterdam, James T., additional, Anderegg, Christine, additional, Anderson, Megan L., additional, Anglin, Deirdre, additional, Ankel, Felix, additional, Arora, Sanjay, additional, Aufderheide, Tom P., additional, Ban, Kevin M., additional, Baran, Emily, additional, Bardsley, Christina E. Hantsch, additional, Barkin, Adam Z., additional, Barnosky, Andrew R., additional, Barsan, William G., additional, Becker, Bruce M., additional, Bengiamin, Rimon N., additional, Berg, Marc D., additional, Berg, Robert A., additional, Berkowitz, Carol D., additional, Bernstein, Edward, additional, Bernstein, Judith, additional, Bessen, Howard A., additional, Bhatia, Kriti, additional, Bilden, Elisabeth F., additional, Birnbaumer, Diane M., additional, Biros, Michelle H., additional, Bitterman, Robert A., additional, Blackwell, Thomas H., additional, Blum, Frederick C., additional, Blumen, Ira J., additional, Bocock, Jennifer M., additional, Bolgiano, Edward B., additional, Bontempo, Laura J., additional, Brady, William J., additional, Braithwaite, Sabina, additional, Brown, Calvin A., additional, Brown, James E., additional, Brunette, Douglas D., additional, Budhram, Gavin R., additional, Bunney, E. Bradshaw, additional, Burbulys, David, additional, Burns, Michael J., additional, Byyny, Richard L., additional, Cahill, John D., additional, Calder, Kirsten K., additional, Cantor, Richard M., additional, Caplen, Stuart M., additional, Carlson, Andrea, additional, Chan, Theodore C., additional, Chen, Lei, additional, Choi, Stephen B., additional, Clark, Richard F., additional, Clement, Philip A., additional, Coates, Wendy C., additional, Collier, Robert E., additional, Collings, Jamie L., additional, Colucciello, Stephen A., additional, Colwell, Christopher B., additional, Conway, Edward E., additional, Cooke, Jeremy L., additional, Cooper, Mary Ann, additional, Cordle, Randolph J., additional, Craig, Sandy A., additional, Cranmer, Hilarie, additional, Crocco, Todd J., additional, Croskerry, Pat, additional, Cwinn, A. Adam, additional, Cydulka, Rita K., additional, Danzl, Daniel F., additional, Davitt, Ana M., additional, Daya, Mohamud, additional, Delaney, Kathleen A., additional, Delbridge, Theodore R., additional, Lorenzo, Robert A. De, additional, Derlet, Robert W., additional, Desai, Shoma, additional, Dolcourt, Bram A., additional, Duvivier, Evelyn H., additional, Easter, Joshua S., additional, Eckstein, Marc, additional, Eisenhauer, Mary, additional, Emery, Matt, additional, Falk, Jay L., additional, Feng, Sing-Yi, additional, Fernández-Frackelton, Madonna, additional, Fiechtl, James F., additional, Finnell, John T., additional, Fitch, Robert W., additional, Foran, Mark, additional, Gallagher, E. John, additional, Garber, Boris, additional, Gausche-Hill, Marianne, additional, Gebhart, Mark E., additional, Geiderman, Joel M., additional, Gibbs, Michael A., additional, Glass, Casey M., additional, Goldberg, Richard, additional, Gough, John E., additional, Graff, Louis, additional, Gray, Richard O., additional, Gross, Eric, additional, Guisto, John A., additional, Guss, David A., additional, Gussow, Leon, additional, Habal, Rania, additional, Haile-Mariam, Tenagne, additional, Hamilton, Glenn C., additional, Hargarten, Stephen W., additional, Harrigan, Richard A., additional, Heegaard, William G., additional, Heer, Jag S., additional, Heilpern, Katherine L., additional, Hemphill, Robin R., additional, Henderson, Sean O., additional, Hendrickson, Robert G., additional, Henneman, Philip L., additional, Hern, Jr., H. Gene, additional, Ho, Kendall, additional, Hockberger, Robert S., additional, Hoffman, Robert S., additional, Honigman, Benjamin, additional, Horeczko, Timothy, additional, Hostetler, Mark A., additional, Houry, Debra E., additional, Huff, J. Stephen, additional, Hung, Oliver, additional, Hutson, H. Range, additional, Inaba, Alson S., additional, Isenhour, Jennifer L., additional, Iserson, Kenneth V., additional, Jackimczyk, Kenneth, additional, Jagoda, Andy, additional, James, Thea L., additional, Janz, Timothy G., additional, Jones, Alan, additional, Jones, James B., additional, Jones, Jonathan S., additional, Jouriles, Nicholas J., additional, Kaji, Amy H., additional, Kalbfleisch, Norman, additional, Kao, Louise, additional, Katz, Dan, additional, Keadey, Matthew T., additional, Kercher, Eugene E., additional, Kiai, Kianusch, additional, King, Kelly E., additional, Kirelik, Susan, additional, Klein, Eileen J., additional, Kline, Jeffrey A., additional, Knaut, Andrew L., additional, Koenig, Kristi L., additional, Kontrick, Amy V., additional, Kornblau, Dina Halpern, additional, Kosowsky, Joshua M., additional, Kothari, Rashmi U., additional, Krauss, Baruch, additional, Kulig, Ken, additional, Kwiatkowski, Thomas, additional, Lavoie, Frank W., additional, Lavonas, Eric J., additional, Lee, Christopher C., additional, Lee, David C., additional, Lehrmann, Jill F., additional, Lerner, E. Brooke, additional, Levine, Michael D., additional, Lewis, Roger J., additional, Lin, Michelle, additional, Ling, Louis J., additional, Lipsky, Ari M., additional, Losman, Eve D., additional, Lowell, Mark J., additional, Lowery, Douglas W., additional, Ly, Binh T., additional, Lyn, Everett T., additional, Mahadevan, Malcolm, additional, Mahoney, Brian D., additional, Mailhot, Thomas, additional, Mallon, William K., additional, Maloney, Jr., Gerald E., additional, Mandavia, Diku P., additional, Manno, Mariann, additional, Marco, Catherine A., additional, Markovchick, Vincent, additional, Martel, Marc L., additional, Marx, John A., additional, Mayersak, Ryanne J., additional, Mazor, Suzan S., additional, McCollough, Maureen, additional, McKay, Mary Pat, additional, McKenzie, L. Kendall, additional, McKeown, Nathanael J., additional, McManus, John, additional, McMicken, David B., additional, McQuillen, Kemedy K., additional, Meislin, Harvey W., additional, Melio, Frantz R., additional, Meurer, William J., additional, Mick, Nathan W., additional, Miner, James R., additional, Mitchell, Connie, additional, Moore, Gregory P., additional, Moran, Gregory J., additional, Morrison, Laurie J., additional, Muelleman, Robert L., additional, Murray, Lindsay, additional, Murphy, Michael F., additional, Nadkarni, Vinay M., additional, Nakamura, Yoko, additional, Nelson, Lewis S., additional, Neumar, Robert W., additional, Newton, Edward J., additional, Newton, Kim, additional, Niemann, James T., additional, Nowak, Richard M., additional, O’Brien, John F., additional, Olshaker, Jonathan S., additional, Otten, Edward J., additional, Oyama, Leslie C., additional, Pallin, Daniel J., additional, Paris, Paul M., additional, Perina, Debra, additional, Perron, Andrew D., additional, Perry, Shawna J., additional, Peterson, Michael A., additional, Pfaff, James A., additional, Pfeil, Sharon, additional, Phillips, William James, additional, Platt, Melissa, additional, Polis, Michael Alan, additional, Pollack, Charles V., additional, Price, Timothy G., additional, Purcell, Thomas B., additional, Ramanujam, Prasanthi, additional, Rao, Rama B., additional, Raukar, Neha P., additional, Rhee, James W., additional, Richards, David B., additional, Richards, John R., additional, Roberts, David J., additional, Rodenberg, Howard, additional, Rodgers, Kevin G., additional, Rothman, Richard E., additional, Rubin, David H., additional, Rund, Douglas A., additional, Runyon, Michael S., additional, Russi, Christopher S., additional, Salhi, Bisan A., additional, Santen, Sally A., additional, Saveanu, Radu V., additional, Scarfone, Richard J., additional, Schmidt, Michael J., additional, Schneider, Diana C., additional, Schultz, Carl H., additional, Schwartz, Richard B., additional, Scott, Susan M., additional, Seger, Donna L., additional, Seiden, Jeffrey A., additional, Seirafi, Jennifer, additional, Sercombe, Clare T., additional, Sexton, Joseph D., additional, Shapiro, Marc J., additional, Shapiro, Nathan I., additional, Sharieff, Ghazala Q., additional, Sharma, Rahul, additional, Shearer, Peter, additional, Shih, Richard D., additional, Shoenberger, Jan M., additional, Shockley, Lee W., additional, Silbergleit, Robert, additional, Simon, Barry C., additional, Singer, Adam J., additional, Singer, Jonathan I., additional, Singh, Amardeep, additional, Slaughter, Laura, additional, Smith, Jeffrey Paul, additional, Smock, William Spafford, additional, Sokolove, Peter E., additional, Soroff, Harry S., additional, Squire, Benjamin, additional, Stettler, Brian A., additional, Stewart, Sara T., additional, Stocker, David M., additional, Stone, Susan, additional, Strote, Jared, additional, Swadron, Stuart P., additional, Tadros, Allison, additional, Taira, Breena R., additional, Talan, David A., additional, Tayal, Vivek S., additional, Thomas, Stephen H., additional, Tibbles, Carrie D., additional, Tobias, Joshua J., additional, Tokarski, Glenn F., additional, Tomaszewski, Christian, additional, Torbati, Sam S., additional, Torrey, Susan P., additional, Tran, T. Paul, additional, Ugras-Rey, Sandra, additional, Vakil, Monira, additional, Vary, Marshall G., additional, Velez, Larissa I., additional, Vicario, Salvator, additional, Vissers, Robert J., additional, Walls, Ron M., additional, Watson, Mark, additional, Wax, Paul M., additional, Wears, Robert L., additional, Weber, Ellen J., additional, West, Hugh H., additional, Wheatley, Matthew A., additional, White, Benjamin A., additional, White, Suzanne R., additional, Wiebe, Robert A., additional, Wightman, John M., additional, Williams, Saralyn R., additional, Winter, Adria O., additional, Wittler, Mary A., additional, Wolfe, Jeannette M., additional, Wolfson, Allan B., additional, H. Woolfrey, Karen G., additional, Woolfrey, Michael, additional, Wright, Joshua L., additional, Yang, Samuel, additional, Yaron, Michael, additional, Yealy, Donald M., additional, Young, Amy, additional, Young, Kelly D., additional, Younger, John G., additional, Zane, Richard, additional, Zich, David K., additional, Zimmer, Gary D., additional, Zink, Brian J., additional, Zull, David, additional, and Zun, Leslie S., additional
- Published
- 2010
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- View/download PDF
17. A prospective cluster-randomized trial to implement the Canadian CT Head Rule in emergency departments
- Author
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Stiell, Ian G., MD MSc, Clement, Catherine M., RN, Grimshaw, Jeremy M., MBChB PhD, Brison, Robert J., MD MPH, Rowe, Brian H., MD MSc, Lee, Jacques S., MD MSc, Shah, Amit, MD, Brehaut, Jamie, PhD, Holroyd, Brian R., MD, Schull, Michael J., MD MSc, McKnight, R. Douglas, MD, Eisenhauer, Mary A., MD, Dreyer, Jonathan, MD, Letovsky, Eric, MD, Rutledge, Tim, MD, MacPhail, Iain, MD, Ross, Scott, MD, Perry, Jeffrey J., MD, Ip, Urbain, MD, Lesiuk, Howard, MD, Bennett, Carol, MSc, and Wells, George A., PhD
- Published
- 2010
- Full Text
- View/download PDF
18. Library Sprouts: Cultivating Innovative Partnerships for Early Learning
- Author
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Eisenhauer, Mary Jane
- Subjects
Early Childhood Education ,Teacher Education and Professional Development - Published
- 2018
19. The Ontario trial of active compression-decompression cardiopulmonary resuscitation for in-hospital and prehospital cardiac arrest
- Author
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Stiell, Ian G., Hebert, Paul C., Wells, George A., Laupacis, Andreas, Vandemheen, Katherine, Dreyer, Jonathan F., Eisenhauer, Mary A., Gibson, John, Higginson, Lyall A.J., Kirby, Ann S., Mahon, Jeffrey L., Maloney, Justin P., and Weitzman, Brian N.
- Subjects
CPR (First aid) -- Evaluation ,Cardiac arrest -- Care and treatment - Abstract
Active compression-decompression cardiopulmonary resuscitation (ACD CPR) does not appear to be more effective than regular CPR. During ACD CPR, the rescuer uses a suction device that allows the chest to expand, or decompress, following each compression. Research has suggested that this may improve blood flow and ventilation. Researchers followed 773 people who developed cardiac arrest in a hospital and 1,011 people who arrested in the community and were transported to a hospital. Approximately half of both groups received regular CPR and half received ACD CPR. ACD CPR did not improve survival rates at one hour or at hospital discharge. This was true for the groups overall and for subgroups with specific characteristics, such as age, type of arrhythmia that led to cardiac arrest or how soon they received CPR. Many of the rescuers found it very difficult to administer ACD CPR., Objective. - To compare the impact of active compression-decompression (ACD) cardiopulmonary resuscitation (CPR) and standard CPR on the outcomes of in-hospital and prehospital victims of cardiac arrest. Design. - Randomized controlled trial with blinding of allocation using a sealed container. Settings. - (1) Emergency departments, wards, and intensive care units of 5 university hospitals and (2) all locations outside hospitals in 2 midsized cities. Patients. - A total of 1784 adults who had cardiac arrest. Intervention. - Patients received either standard or ACD CPR throughout resuscitation. Main Outcome Measures. - Survival for 1 hour and to hospital discharge and the modified Mini-Mental State Examination (MMSE). Results. - All characteristics were similar in the standard and ACD CPR groups for the 773 in-hospital patients and the 1011 prehospital patients. For in-hospital patients, there were no significant differences between the standard (n=368) and ACD (n=405) CPR groups in survival for 1 hour (35.1 % vs 34.6%; P=.89), in survival until hospital discharge (1 1.4% vs 10.4%; P=.64), or in the median MMSE score of survivors (37 in both groups). For patients who collapsed outside the hospital, there were also no significant differences between the standard (n=510) and ACD (n=501) CPR groups in survival for 1 hour (16.5% vs 18.2%; P=.48), in survival to hospital discharge (3.7% vs 4.6%; P=.49), or in the median MMSE score of survivors (35 in both groups). Exploration of clinically important subgroups failed to identify any patients who appeared to benefit from ACD CPR. Conclusions. - ACD CPR did not improve survival or neurologic outcomes in any group of patients with cardiac arrest.
- Published
- 1996
20. Retrospective application of the NEXUS low-risk criteria for cervical spine radiography in Canadian emergency departments
- Author
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Dickinson, Garth, Stiell, Ian G, Schull, Michael, Brison, Robert, Clement, Catherine M, Vandemheen, Katherine L, Cass, Daniel, McKnight, Douglas, Greenberg, Gary, Worthington, James R, Reardon, Mark, Morrison, Laurie, Eisenhauer, Mary A, Dreyer, Jonathan, and Wells, George A
- Published
- 2004
- Full Text
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21. The Canadian C-spine rule performs better than unstructured physician judgment
- Author
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Bandiera, Glen, Stiell, Ian G., Wells, George A., Clement, Catherine, De Maio, Valerie, Vandemheen, Katherine L., Greenberg, Gary H., Lesiuk, Howard, Brison, Robert, Cass, Daniel, Dreyer, Jonathan, Eisenhauer, Mary A., MacPhail, Iain, McKnight, R. Douglas, Morrison, Laurie, Reardon, Mark, Schull, Michael, and Worthington, James
- Published
- 2003
22. The Canadian C-Spine Rule for Radiography in Alert and Stable Trauma Patients
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Stiell, Ian G., Wells, George A., Vandemheen, Katherine L., Clement, Catherine M., Lesiuk, Howard, De Maio, Valerie J., Laupacis, Andreas, Schull, Michael, McKnight, R. Douglas, Verbeek, Richard, Brison, Robert, Cass, Daniel, Dreyer, Jonathan, Eisenhauer, Mary A., Greenberg, Gary H., MacPhail, Iain, Morrison, Laurie, Reardon, Mark, and Worthington, James
- Published
- 2001
23. Canadian CT head rule study for patients with minor head injury: methodology for phase II (validation and economic analysis)
- Author
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Stiell, Ian G., Lesiuk, Howard, Wells, George A., Coyle, Douglas, McKnight, R. Douglas, Brison, Robert, Clement, Catherine, Eisenhauer, Mary A., Greenberg, Gary H., MacPhail, Iain, Reardon, Mark, Worthington, James, Verbeek, Richard, Rowe, Brian, Cass, Daniel, Dreyer, Jonathan, Holroyd, Brian, Morrison, Laurie, Schull, Michael, and Laupacis, Andreas
- Published
- 2001
24. The canadian CT head rule study for patients with minor head injury: Rationale, objectives, and methodology for phase I (derivation)
- Author
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Stiell, Ian G., Lesiuk, Howard, Wells, George A., McKnight, R. Douglas, Brison, Robert, Clement, Catherine, Eisenhauer, Mary A., Greenberg, Gary H., MacPhail, Iain, Reardon, Mark, Worthington, James, Verbeek, Richard, Rowe, Brian, Cass, Daniel, Dreyer, Jonathan, Holroyd, Brian, Morrison, Laurie, Schull, Michael, and Laupacis, Andreas
- Published
- 2001
25. Variation in ED Use of Computed Tomography for Patients With Minor Head Injury
- Author
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Stiell, Ian G, Wells, George A, Vandemheen, Katherine, Laupacis, Andreas, Brison, Robert, Eisenhauer, Mary A, Greenberg, Gary H, MacPhail, Iain, McKnight, R Douglas, Reardon, Mark, Verbeek, Richard, Worthington, James, and Lesiuk, Howard
- Published
- 1997
26. Variation in emergency department use of cervical spine radiography for alert, stable trauma patients
- Author
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Stiell, Ian G., Wells, George A., Vandemheen, Katherine, Laupacis, Andreas, Brison, Robert, Eisenhauer, Mary A., Greenberg, Gary H., MacPhail, Iain, McKnight, R. Douglas, Reardon, Mark, Verbeek, Richard, Worthington, James, and Lesiuk, Howard
- Published
- 1997
27. Can a Day 4 Bone Scan Accurately Determine the Presence or Absence of Scaphoid Fracture?
- Author
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Murphy, David G., Eisenhauer, Mary A., Powe, John, and Pavlofsky, William
- Subjects
Health - Abstract
Byline: David G Murphy, Mary A Eisenhauer, John Powe, William Pavlofsky Abstract: Study objective: To evaluate the accuracy of day 4 bone scans in predicting the presence or absence of fracture in patients with 'clinical scaphoid fracture.' Design: Prospective sensitivity study of ED patients with clinical scaphoid fractures. Each patient was immobilized in a thumb spica cast and had day 4 bone scans of both wrists and hands. Blinded day 4 bone scan results were ultimately compared with the diagnosis on day 14 when patients returned for repeat clinical examination and radiographs. In cases of equivocal radiographic or clinical examination results, a day 14 bone scan was performed. Setting: Two tertiary care teaching hospital emergency departments. Participants: All ED patients older than 16 years with the diagnosis of clinical scaphoid fracture were eligible. Results: Ninety-nine patients were enrolled and successfully completed the study protocol from October 1990 through November 1992. One patient had bilateral injury, for a total of 100 completed studies. Day 4 bone scans were 100% sensitive and 92% specific, for a positive predictive value of 65%, a negative predictive value of 100%, and accuracy of 93% (95% confidence interval, 88% to 98%). Many other types of fractures were identified on the day 4 scans, including those of the triquetra, distal radius, capitate, hamate, trapezoid, trapezium, and metacarpals. Conclusion: Day 4 bone scans are an accurate means of ruling out scaphoid fracture. However, because of a significant number of false-positive scans at day 4, they do not reliably confirm the diagnosis of scaphoid fracture. The bone scans also permitted identification of several other wrist fractures that had not been radiographically apparent. [Murphy DG, Eisenhauer MA, Powe J, Pavlofsky W: Can a day 4 bone scan accurately determine the presence or absence of scaphoid fracture? Ann Emerg Med October 1995;26:434-438.] Article History: Received 22 November 1994; Revised 21 March 1995; Accepted 10 April 1995 Article Note: (footnote) [star] From the Department of Medicine* and Diagnostic Radiology and Nuclear Medicinea , University of Western Ontario, London, Ontario, Canada., [star][star] Supported by the Emergency Medicine Associates Research Fund and the Lawson Research Fund., a Address for reprints: David G Murphy, MD, FRCPC, DABEM, Department of Emergency Medicine, St Joseph's Health Centre, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2, 519-646-6100, ext 4233, Fax 519-646-6038, aa Reprint no. 47/1/66975
- Published
- 1995
28. The Canadian CT Head Rule for patients with minor head injury
- Author
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Stiell, Ian G, Wells, George A, Vandemheen, Katherine, Clement, Catherine, Lesiuk, Howard, Laupacis, Andreas, McKnight, R Douglas, Verbeek, Richard, Brison, Robert, Cass, Daniel, Eisenhauer, Mary A, Greenberg, Gary H, and Worthington, James
- Subjects
CT imaging ,Head injuries -- Diagnosis - Published
- 2001
29. Factors influencing time to computed tomography in emergency department patients with suspected subarachnoid haemorrhage
- Author
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Khan, Maryam, primary, Sivilotti, Marco L A, additional, Bullard, Michael J, additional, Émond, Marcel, additional, Sutherland, Jane, additional, Worster, Andrew, additional, Hohl, Corinne M, additional, Lee, Jacques S, additional, Eisenhauer, Mary, additional, Pauls, Merril, additional, Lesiuk, Howard, additional, Wells, George A, additional, Stiell, Ian G, additional, and Perry, Jeffrey J, additional
- Published
- 2016
- Full Text
- View/download PDF
30. Detection and Quantitation of Bacterial Acylhomoserine Lactone Quorum Sensing Molecules via Liquid Chromatography–Isotope Dilution Tandem Mass Spectrometry
- Author
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May, Amanda L., primary, Eisenhauer, Mary E., additional, Coulston, Kristen S., additional, and Campagna, Shawn R., additional
- Published
- 2012
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31. Pancreatic β-Cell Death in Response to Pro-Inflammatory Cytokines Is Distinct from Genuine Apoptosis
- Author
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Collier, J. Jason, primary, Burke, Susan J., additional, Eisenhauer, Mary E., additional, Lu, Danhong, additional, Sapp, Renee C., additional, Frydman, Carlie J., additional, and Campagna, Shawn R., additional
- Published
- 2011
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32. High risk clinical characteristics for subarachnoid haemorrhage in patients with acute headache: prospective cohort study
- Author
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Perry, Jeffrey J., Stiell, Ian G., Sivilotti, Marco L.A., Bullard, Michael J., Lee, Jacques S., Eisenhauer, Mary, Symington, Cheryl, Mortensen, Melodie, Sutherland, Jane, Lesiuk, Howard, and Wells, George A.
- Subjects
Subarachnoid hemorrhage -- Risk factors ,Subarachnoid hemorrhage -- Diagnosis ,Subarachnoid hemorrhage -- Care and treatment - Published
- 2010
33. The utility of a bone scan in the diagnosis of clinical scaphoid fracture
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Murphy, David, primary and Eisenhauer, Mary, additional
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- 1994
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34. Canadian C-Spine Rule study for alert and stable trauma patients: II. Study objectives and methodology.
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Stiell, Ian G., Wells, George A., McKnight, Douglas, Brison, Robert, Lesiuk, Howard, Clement, Catherine M., Eisenhauer, Mary A., Greenberg, Gary H., MacPhail, Iain, Reardon, Mark, Worthington, James, Verbeek, Richard, Dreyer, Jonathan, Cass, Daniel, Schull, Michael, Morrison, Laurie, Rowe, Brian, Holroyd, Brian, Bandiera, Glen, and Laupacis, Andreas
- Subjects
EMOTIONAL trauma ,CERVICAL vertebrae ,EMERGENCY medical services - Abstract
Clinical prediction rules are decision-making tools that incorporate three or more variables from the history, physical examination or simple tests. They help clinicians make diagnostic or therapeutic decisions by standardizing the collection and interpretation of clinical data. There is growing interest in the methodological standards for their development and validation. This article describes the methods used to derive the Canadian C-Spine Rule and provides a valuable reference for investigators planning to develop future clinical prediction rules. [ABSTRACT FROM AUTHOR]
- Published
- 2002
35. Canadian C-Spine Rule study for alert and stable trauma patients: I. Background and rationale
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Stiell, Ian G., Wells, George A., McKnight, R. Douglas, Brison, Robert, Lesiuk, Howard, Clement, Catherine M., Eisenhauer, Mary A., Greenberg, Gary H., MacPhail, Iain, Reardon, Mark, Worthington, James, Verbeek, Richard, Dreyer, Jonathan, Cass, Daniel, Schull, Michael, Morrison, Laurie, Rowe, Brian, Holroyd, Brian, Bandiera, Glen, and Laupacis, Andreas
- Abstract
ABSTRACTThis paper is Part I of a 2-part series to describe the background and methodology for the Canadian C-Spine Rule study to develop a clinical decision rule for rational imaging in alert and stable trauma patients. Current use of radiography is inefficient and variable, in part because there has been a lack of evidence-based guidelines to assist emergency physicians. Clinical decision rules are research-based decision-making tools that incorporate 3 or more variables from the history, physical examination or simple tests. The Canadian CT Head and C-Spine (CCC) Study is a large collaborative effort to develop clinical decision rules for the use of CT head in minor head injury and for the use of cervical spine radiography in alert and stable trauma victims. Part I details the background and rationale for the development of the Canadian C-Spine Rule. Part II will describe in detail the objectives and methods of the Canadian C-Spine Rule study.
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- 2002
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36. Application of Liquid Chromatography-Tandem Mass Spectrometry Techniques to the Study of Two Biological Systems
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Eisenhauer, Mary E.
- Abstract
Quorum sensing is a type of bacterial cell-cell communication that uses diffusible signaling molecules to allow the regulation of gene expression based on cell density. The two types of signaling molecules discussed here are autoinducer-2 (AI-2) and a class of signaling molecules of the N-acylhomoserine lactone type (AHL) also known as autoinducer-1 (AI-1). The biosynthesis of both of these molecules has origins in a metabolic pathway. Although undisputed in some cases, the role of AI-2 and AHLs in bacterial systems has come into question. Here, the functionalities of these molecules were investigated by utilizing isotope-labeled versions of both AI-2 and AHLs in conjunction with liquid chromatography tandem mass spectrometry in order to quantify the natural abundance of these molecules in various bacterial cultures. Presented in this thesis are, a synthesis for doubly-deuterated AHLs as well as chromatographic and spectrometric methods for the detection and quantitation of these molecules. Additionally, a series of relevant biological studies which effectively and prolifically utilize these synthetic and analytical techniques are presented here. The selective destruction of beta-cell mass in the Langerhans of the pancreas is known to cause Type 1 diabetes mellitus (T1DM). Currently, many key aspects of this autoimmune disease remain unclear, including the exact mechanism of beta-cell death. In a collaborative project with Dr. J. Jason Collier, we sought to test the hypothesis that different mechanisms of cell death will present discrete phenotypic profiles which can be distinguished by a specific metabolic response in response to the appropriate stimuli. A second project presented in this thesis is the development and implementation of a method to profile the metabolic signatures of two types of pancreatic beta-cell death using tandem mass spectrometry techniques. Using 832/13 rat insulinoma cells, the metabolite pools of cells exposed to either pro-inflammatory cytokines or known apoptosis inducers, such as camptothecin, were analyzed. In this investigation, it was found that this method was effective in defining reproducible metabolic differences in each sample tested. Taken together with complementary methods used in the Collier lab, the results collectively demonstrate that pancreatic beta-cells undergo apoptosis in response to camptothecin, but not pro-inflammatory cytokines.
- Published
- 2011
37. CHAPTER 48 - Wrist and Forearm
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Woolfrey, Karen G.H., Woolfrey, Michael R., and Eisenhauer, Mary A.
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38. Contributors
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Aaron, Cynthia K., Abbott, Jean T., Abu-Laban, Riyad B., Adams, Bruce D., Adams, James G., Adams, Stephen L., Adirim, Terry A., Alagappan, Kumar, Amsterdam, James T., Anderegg, Christine, Anderson, Megan L., Anglin, Deirdre, Ankel, Felix, Arora, Sanjay, Aufderheide, Tom P., Ban, Kevin M., Baran, Emily, Bardsley, Christina E. Hantsch, Barkin, Adam Z., Barnosky, Andrew R., Barsan, William G., Becker, Bruce M., Bengiamin, Rimon N., Berg, Marc D., Berg, Robert A., Berkowitz, Carol D., Bernstein, Edward, Bernstein, Judith, Bessen, Howard A., Bhatia, Kriti, Bilden, Elisabeth F., Birnbaumer, Diane M., Biros, Michelle H., Bitterman, Robert A., Blackwell, Thomas H., Blum, Frederick C., Blumen, Ira J., Bocock, Jennifer M., Bolgiano, Edward B., Bontempo, Laura J., Brady, William J., Braithwaite, Sabina, Brown, Calvin A., III, Brown, James E., Brunette, Douglas D., Budhram, Gavin R., Bunney, E. Bradshaw, Burbulys, David, Burns, Michael J., Byyny, Richard L., Cahill, John D., Calder, Kirsten K., Cantor, Richard M., Caplen, Stuart M., Carlson, Andrea, Chan, Theodore C., Chen, Lei, Choi, Stephen B., Clark, Richard F., Clement, Philip A., Coates, Wendy C., Collier, Robert E., Collings, Jamie L., Colucciello, Stephen A., Colwell, Christopher B., Conway, Edward E., Jr., Cooke, Jeremy L., Cooper, Mary Ann, Cordle, Randolph J., Craig, Sandy A., Cranmer, Hilarie, Crocco, Todd J., Croskerry, Pat, Cwinn, A. Adam, Cydulka, Rita K., Danzl, Daniel F., Davitt, Ana M., Daya, Mohamud, Delaney, Kathleen A., Delbridge, Theodore R., Lorenzo, Robert A. De, Derlet, Robert W., Desai, Shoma, Dolcourt, Bram A., Duvivier, Evelyn H., Easter, Joshua S., Eckstein, Marc, Eisenhauer, Mary, Emery, Matt, Falk, Jay L., Feng, Sing-Yi, Fernández-Frackelton, Madonna, Fiechtl, James F., Finnell, John T., II, Fitch, Robert W., Foran, Mark, Gallagher, E. John, Garber, Boris, Gausche-Hill, Marianne, Gebhart, Mark E., Geiderman, Joel M., Gibbs, Michael A., Glass, Casey M., Goldberg, Richard, Gough, John E., Graff, Louis, IV, Gray, Richard O., Gross, Eric, Guisto, John A., Guss, David A., Gussow, Leon, Habal, Rania, Haile-Mariam, Tenagne, Hamilton, Glenn C., Hargarten, Stephen W., Harrigan, Richard A., Heegaard, William G., Heer, Jag S., Heilpern, Katherine L., Hemphill, Robin R., Henderson, Sean O., Hendrickson, Robert G., Henneman, Philip L., Hern, Jr., H. Gene, Ho, Kendall, Hockberger, Robert S., Hoffman, Robert S., Honigman, Benjamin, Horeczko, Timothy, Hostetler, Mark A., Houry, Debra E., Huff, J. Stephen, Hung, Oliver, Hutson, H. Range, Inaba, Alson S., Isenhour, Jennifer L., Iserson, Kenneth V., Jackimczyk, Kenneth, Jagoda, Andy, James, Thea L., Janz, Timothy G., Jones, Alan, Jones, James B., Jones, Jonathan S., Jouriles, Nicholas J., Kaji, Amy H., Kalbfleisch, Norman, Kao, Louise, Katz, Dan, Keadey, Matthew T., Kercher, Eugene E., Kiai, Kianusch, King, Kelly E., Kirelik, Susan, Klein, Eileen J., Kline, Jeffrey A., Knaut, Andrew L., Koenig, Kristi L., Kontrick, Amy V., Kornblau, Dina Halpern, Kosowsky, Joshua M., Kothari, Rashmi U., Krauss, Baruch, Kulig, Ken, Kwiatkowski, Thomas, Lavoie, Frank W., Lavonas, Eric J., Lee, Christopher C., Lee, David C., Lehrmann, Jill F., Lerner, E. Brooke, Levine, Michael D., Lewis, Roger J., Lin, Michelle, Ling, Louis J., Lipsky, Ari M., Losman, Eve D., Lowell, Mark J., Lowery, Douglas W., III, Ly, Binh T., Lyn, Everett T., Mahadevan, Malcolm, Mahoney, Brian D., Mailhot, Thomas, Mallon, William K., Maloney, Jr., Gerald E., Mandavia, Diku P., Manno, Mariann, Marco, Catherine A., Markovchick, Vincent, Martel, Marc L., Marx, John A., Mayersak, Ryanne J., Mazor, Suzan S., McCollough, Maureen, McKay, Mary Pat, McKenzie, L. Kendall, McKeown, Nathanael J., McManus, John, McMicken, David B., McQuillen, Kemedy K., Meislin, Harvey W., Melio, Frantz R., Meurer, William J., Mick, Nathan W., Miner, James R., Mitchell, Connie, Moore, Gregory P., Moran, Gregory J., Morrison, Laurie J., Muelleman, Robert L., Murray, Lindsay, Murphy, Michael F., Nadkarni, Vinay M., Nakamura, Yoko, Nelson, Lewis S., Neumar, Robert W., Newton, Edward J., Newton, Kim, Niemann, James T., Nowak, Richard M., O’Brien, John F., Olshaker, Jonathan S., Otten, Edward J., Oyama, Leslie C., Pallin, Daniel J., Paris, Paul M., Perina, Debra, Perron, Andrew D., Perry, Shawna J., Peterson, Michael A., Pfaff, James A., Pfeil, Sharon, Phillips, William James, Platt, Melissa, Polis, Michael Alan, Pollack, Charles V., Price, Timothy G., Purcell, Thomas B., Ramanujam, Prasanthi, Rao, Rama B., Raukar, Neha P., Rhee, James W., Richards, David B., Richards, John R., Roberts, David J., Rodenberg, Howard, Rodgers, Kevin G., Rothman, Richard E., Rubin, David H., Rund, Douglas A., Runyon, Michael S., Russi, Christopher S., Salhi, Bisan A., Santen, Sally A., Saveanu, Radu V., Scarfone, Richard J., Schmidt, Michael J., Schneider, Diana C., Schultz, Carl H., Schwartz, Richard B., Scott, Susan M., Seger, Donna L., Seiden, Jeffrey A., Seirafi, Jennifer, Sercombe, Clare T., Sexton, Joseph D., Shapiro, Marc J., Shapiro, Nathan I., Sharieff, Ghazala Q., Sharma, Rahul, Shearer, Peter, Shih, Richard D., Shoenberger, Jan M., Shockley, Lee W., Silbergleit, Robert, Simon, Barry C., Singer, Adam J., Singer, Jonathan I., Singh, Amardeep, Slaughter, Laura, Smith, Jeffrey Paul, Smock, William Spafford, Sokolove, Peter E., Soroff, Harry S., Squire, Benjamin, Stettler, Brian A., Stewart, Sara T., Stocker, David M., Stone, Susan, Strote, Jared, Swadron, Stuart P., Tadros, Allison, Taira, Breena R., Talan, David A., Tayal, Vivek S., Thomas, Stephen H., Tibbles, Carrie D., Tobias, Joshua J., Tokarski, Glenn F., Tomaszewski, Christian, Torbati, Sam S., Torrey, Susan P., Tran, T. Paul, Ugras-Rey, Sandra, Vakil, Monira, Vary, Marshall G., Velez, Larissa I., Vicario, Salvator, Vissers, Robert J., Walls, Ron M., Watson, Mark, Wax, Paul M., Wears, Robert L., Weber, Ellen J., West, Hugh H., Wheatley, Matthew A., White, Benjamin A., White, Suzanne R., Wiebe, Robert A., Wightman, John M., Williams, Saralyn R., Winter, Adria O., Wittler, Mary A., Wolfe, Jeannette M., Wolfson, Allan B., H. Woolfrey, Karen G., Woolfrey, Michael, Wright, Joshua L., Yang, Samuel, Yaron, Michael, Yealy, Donald M., Young, Amy, Young, Kelly D., Younger, John G., Zane, Richard, Zich, David K., Zimmer, Gary D., Zink, Brian J., Zull, David, and Zun, Leslie S.
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39. Differentiation between traumatic tap and aneurysmal subarachnoid hemorrhage: prospective cohort study.
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Perry JJ, Alyahya B, Sivilotti ML, Bullard MJ, Émond M, Sutherland J, Worster A, Hohl C, Lee JS, Eisenhauer MA, Pauls M, Lesiuk H, Wells GA, and Stiell IG
- Subjects
- Adult, Canada, Diagnosis, Differential, Diagnostic Imaging, Erythrocyte Count, Female, Headache cerebrospinal fluid, Humans, Male, Prospective Studies, Sensitivity and Specificity, Intracranial Aneurysm cerebrospinal fluid, Spinal Puncture adverse effects, Subarachnoid Hemorrhage cerebrospinal fluid
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Objectives: To describe the findings in cerebrospinal fluid from patients with acute headache that could distinguish subarachnoid hemorrhage from the effects of a traumatic lumbar puncture., Design: A substudy of a prospective multicenter cohort study., Setting: 12 Canadian academic emergency departments, from November 2000 to December 2009., Participants: Alert patients aged over 15 with an acute non-traumatic headache who underwent lumbar puncture to rule out subarachnoid hemorrhage., Main Outcome Measure: Aneurysmal subarachnoid hemorrhage requiring intervention or resulting in death., Results: Of the 1739 patients enrolled, 641 (36.9%) had abnormal results on cerebrospinal fluid analysis with >1 × 10(6)/L red blood cells in the final tube of cerebrospinal fluid and/or xanthochromia in one or more tubes. There were 15 (0.9%) patients with aneurysmal subarachnoid hemorrhage based on abnormal results of a lumbar puncture. The presence of fewer than 2000 × 10(6)/L red blood cells in addition to no xanthochromia excluded the diagnosis of aneurysmal subarachnoid hemorrhage, with a sensitivity of 100% (95% confidence interval 74.7% to 100%) and specificity of 91.2% (88.6% to 93.3%)., Conclusion: No xanthochromia and red blood cell count <2000 × 10(6)/L reasonably excludes the diagnosis of aneurysmal subarachnoid hemorrhage. Most patients with acute headache who meet this cut off will need no further investigations and aneurysmal subarachnoid hemorrhage can be excluded as a cause of their headache., (© Perry et al 2015.)
- Published
- 2015
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40. Sensitivity of computed tomography performed within six hours of onset of headache for diagnosis of subarachnoid haemorrhage: prospective cohort study.
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Perry JJ, Stiell IG, Sivilotti ML, Bullard MJ, Emond M, Symington C, Sutherland J, Worster A, Hohl C, Lee JS, Eisenhauer MA, Mortensen M, Mackey D, Pauls M, Lesiuk H, and Wells GA
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- Acute Disease, Diagnostic Errors, Emergency Service, Hospital, Female, Humans, Male, Middle Aged, Prospective Studies, Sensitivity and Specificity, Time Factors, Treatment Outcome, Headache Disorders etiology, Subarachnoid Hemorrhage diagnostic imaging, Tomography, X-Ray Computed methods
- Abstract
Objective: To measure the sensitivity of modern third generation computed tomography in emergency patients being evaluated for possible subarachnoid haemorrhage, especially when carried out within six hours of headache onset., Design: Prospective cohort study., Setting: 11 tertiary care emergency departments across Canada, 2000-9., Participants: Neurologically intact adults with a new acute headache peaking in intensity within one hour of onset in whom a computed tomography was ordered by the treating physician to rule out subarachnoid haemorrhage., Main Outcome Measures: Subarachnoid haemorrhage was defined by any of subarachnoid blood on computed tomography, xanthochromia in cerebrospinal fluid, or any red blood cells in final tube of cerebrospinal fluid collected with positive results on cerebral angiography., Results: Of the 3132 patients enrolled (mean age 45.1, 2571 (82.1%) with worst headache ever), 240 had subarachnoid haemorrhage (7.7%). The sensitivity of computed tomography overall for subarachnoid haemorrhage was 92.9% (95% confidence interval 89.0% to 95.5%), the specificity was 100% (99.9% to 100%), the negative predictive value was 99.4% (99.1% to 99.6%), and the positive predictive value was 100% (98.3% to 100%). For the 953 patients scanned within six hours of headache onset, all 121 patients with subarachnoid haemorrhage were identified by computed tomography, yielding a sensitivity of 100% (97.0% to 100.0%), specificity of 100% (99.5% to 100%), negative predictive value of 100% (99.5% to 100%), and positive predictive value of 100% (96.9% to 100%)., Conclusion: Modern third generation computed tomography is extremely sensitive in identifying subarachnoid haemorrhage when it is carried out within six hours of headache onset and interpreted by a qualified radiologist.
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- 2011
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41. Implementation of the Canadian C-Spine Rule: prospective 12 centre cluster randomised trial.
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Stiell IG, Clement CM, Grimshaw J, Brison RJ, Rowe BH, Schull MJ, Lee JS, Brehaut J, McKnight RD, Eisenhauer MA, Dreyer J, Letovsky E, Rutledge T, MacPhail I, Ross S, Shah A, Perry JJ, Holroyd BR, Ip U, Lesiuk H, and Wells GA
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- Adolescent, Adult, Aged, Aged, 80 and over, Canada, Cluster Analysis, Craniocerebral Trauma diagnosis, Decision Support Systems, Clinical standards, Emergency Service, Hospital statistics & numerical data, Female, Humans, Male, Middle Aged, Young Adult, Cervical Vertebrae injuries, Decision Support Systems, Clinical statistics & numerical data, Diagnostic Imaging statistics & numerical data, Injury Severity Score, Spinal Fractures diagnosis, Wounds, Nonpenetrating diagnosis
- Abstract
Objective: To evaluate the effectiveness of an active strategy to implement the validated Canadian C-Spine Rule into multiple emergency departments., Design: Matched pair cluster randomised trial., Setting: University and community emergency departments in Canada. Participants 11 824 alert and stable adults presenting with blunt trauma to the head or neck at one of 12 hospitals., Interventions: Six hospitals were randomly allocated to the intervention and six to the control. At the intervention sites, active strategies were used to implement the Canadian C-Spine Rule, including education, policy, and real time reminders on radiology requisitions. No specific intervention was introduced to alter the behaviour of doctors requesting cervical spine imaging at the control sites., Main Outcome Measure: Diagnostic imaging rate of the cervical spine during two 12 month before and after periods., Results: Patients were balanced between control and intervention sites. From the before to the after periods, the intervention group showed a relative reduction in cervical spine imaging of 12.8% (95% confidence interval 9% to 16%; 61.7% v 53.3%; P=0.01) and the control group a relative increase of 12.5% (7% to 18%; 52.8% v 58.9%; P=0.03). These changes were significant when both groups were compared (P<0.001). No fractures were missed and no adverse outcomes occurred., Conclusions: Implementation of the Canadian C-Spine Rule led to a significant decrease in imaging without injuries being missed or patient morbidity. Final imaging rates were much lower at intervention sites than at most US hospitals. Widespread implementation of this rule could lead to reduced healthcare costs and more efficient patient flow in busy emergency departments worldwide., Trial Registration: Clinical trials NCT00290875.
- Published
- 2009
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