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13 results on '"Egorova, Emiliya S."'

3. The A-allele of the FTO Gene rs9939609 Polymorphism Is Associated With Decreased Proportion of Slow Oxidative Muscle Fibers and Over-represented in Heavier Athletes

Author

Guilherme, João Paulo L.F., Egorova, Emiliya S., Semenova, Ekaterina A., Kostryukova, Elena S., Kulemin, Nickolay A., Borisov, Oleg V., Khabibova, Sofya A., Larin, Andrey K., Ospanova, Elena A., Pavlenko, Alexander V., Lyubaeva, Ekaterina V., Popov, Daniil V., Lysenko, Evgeny A., Vepkhvadze, Tatiana F., Lednev, Egor M., Govorun, Vadim M., Generozov, Edward V., Ahmetov, Ildus I., and Lancha Junior, Antonio H.

Published
2019
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4. KIBRA Gene Variant Is Associated with Ability in Chess and Science

Author

Ahmetov, Ildus I., primary, Valeeva, Elena V., additional, Yerdenova, Meruert B., additional, Datkhabayeva, Gaukhar K., additional, Bouzid, Amal, additional, Bhamidimarri, Poorna Manasa, additional, Sharafetdinova, Liliya M., additional, Egorova, Emiliya S., additional, Semenova, Ekaterina A., additional, Gabdrakhmanova, Leysan J., additional, Yusupov, Rinat A., additional, Larin, Andrey K., additional, Kulemin, Nikolay A., additional, Generozov, Edward V., additional, Hamoudi, Rifat, additional, Kustubayeva, Almira M., additional, and Rees, Tim, additional

Published
2023
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5. Genome-Wide Association Study of Exercise-Induced Fat Loss Efficiency

Author

Bojarczuk, Aleksandra, primary, Boulygina, Eugenia A., additional, Dzitkowska-Zabielska, Magdalena, additional, Łubkowska, Beata, additional, Leońska-Duniec, Agata, additional, Egorova, Emiliya S., additional, Semenova, Ekaterina A., additional, Andryushchenko, Liliya B., additional, Larin, Andrey K., additional, Generozov, Edward V., additional, Cięszczyk, Pawel, additional, and Ahmetov, Ildus I., additional

Published
2022
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7. Association of gene polymorphisms with body weight changes in prediabetic patients

Author

Valeeva, Farida V, Medvedeva, Mariya S, Khasanova, Kamilya B, Valeeva, Elena V, Kiseleva, Tatyana A, Egorova, Emiliya S, Pickering, Craig, Ahmetov, Ildus I, Valeeva, Farida V, Medvedeva, Mariya S, Khasanova, Kamilya B, Valeeva, Elena V, Kiseleva, Tatyana A, Egorova, Emiliya S, Pickering, Craig, and Ahmetov, Ildus I

Abstract

Recent research has demonstrated that Type 2 Diabetes (T2D) risk is influenced by a number of common polymorphisms, including MC4R rs17782313, PPARG rs1801282, and TCF7L2 rs7903146. Knowledge of the association between these single nucleotide polymorphisms (SNPs) and body weight changes in different forms of prediabetes treatment is still limited. The aim of this study was to investigate the association of polymorphisms within the MC4R, PPARG, and TCF7L2 genes on the risk of carbohydrate metabolism disorders and body composition changes in overweight or obese patients with early carbohydrate metabolism disorders. From 327 patients, a subgroup of 81 prediabetic female patients (48.7 ± 14.8 years) of Eastern European descent participated in a 3-month study comprised of diet therapy or diet therapy accompanied with metformin treatment. Bioelectrical impedance analysis and genotyping of MC4R rs17782313, PPARG rs1801282, and TCF7L2 rs7903146 polymorphisms were performed. The MC4R CC and TCF7L2 TT genotypes were associated with increased risk of T2D (OR = 1.46, p = 0.05 and OR = 2.47, p = 0.006, respectively). PPARG CC homozygotes experienced increased weight loss; however, no additional improvements were experienced with the addition of metformin. MC4R TT homozygotes who took metformin alongside dietary intervention experienced increased weight loss and reductions in fat mass (p < 0.05). We have shown that the obesity-protective alleles (MC4R T and PPARG C) were positively associated with weight loss efficiency. Furthermore, we confirmed the previous association of the MC4R C and TCF7L2 T alleles with T2D risk. [Abstract copyright: © 2022. The Author(s).]

Published
2022

10. AGTR2 gene polymorphism is associated with muscle fibre composition, athletic status and aerobic performance

Author

Mustafina, Leysan J., Naumov, Vladimir A., Cieszczyk, Pawel, Popov, Daniil V., Lyubaeva, Ekaterina V., Kostryukova, Elena S., Fedotovskaya, Olga N., Druzhevskaya, Anastasiya M., Astratenkova, Irina V., Glotov, Andrey S., Alexeev, Dmitry G., Mustafina, Milyausha M., Egorova, Emiliya S., Maciejewska-Karłowska, Agnieszka, Larin, Andrey K., Generozov, Edward V., Nurullin, Ruslan E., Jastrzębski, Zbigniew, Kulemin, Nickolay A., Ospanova, Elena A., Pavlenko, Alexander V., Sawczuk, Marek, Akimov, Egor B., Danilushkina, Anna A., Żmijewski, Piotr, Vinogradova, Olga L., Govorun, Vadim M., and Ahmetov, Ildus I.

Published
2014
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11. AGTR2 and sprint/power performance: a case-control replication study for rs11091046 polymorphism in two ethnicities

Author

Yvert, Thomas P., primary, Zempo, Hirofumi, additional, Gabdrakhmanova, Leysan J., additional, Kikuchi, Naoki, additional, Miyamoto-Mikami, Eri, additional, Murakami, Haruka, additional, Naito, Hisashi, additional, Cieszczyk, Pawel, additional, Leznicka, Katarzyna, additional, Kostryukova, Elena S., additional, Alexeev, Dmitry G., additional, Egorova, Emiliya S., additional, Maciejewska-Skrendo, Agnieszka, additional, Larin, Andrey K., additional, Generozov, Edward V., additional, Kulemin, Nickolay A., additional, Ospanova, Elena A., additional, Pavlenko, Alexander V., additional, Sawczuk, Marek, additional, Zmijewski, Piotr, additional, Lulinska-Kuklik, Ewelina, additional, Govorun, Vadim M., additional, Miyachi, Motohiko, additional, Ahmetov, Ildus I., additional, and Fuku, Noriyuki, additional

Published
2018
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12. AGTR2 and sprint/power performance: a case-control replication study for rs1 1091046 polymorphism in two ethnicities.

Author

Yvert, Thomas P., Zempo, Hirofumi, Gabdrakhmanova, Leysan J., Naoki Kikuchi, Eri Miyamoto-Mikami, Haruka Murakami, Hisashi Naito, Cieszczyk, Pawel, Leznicka, Katarzyna, Kostryukova, Elena S., Alexeev, Dmitry G., Egorova, Emiliya S., Maciejewska-Skrendo, Agnieszka, Larin, Andrey K., Generozov, Edward V., Kulemin, Nickolay A., Ospanova, Elena A., Pavlenko, Alexander V., Sawczuk, Marek, and Zmijewski, Piotr

Abstract

We aimed to replicate, in a specific athletic event cohort (only track and field) and in two different ethnicities (Japanese and East European, i.e. Russian and Polish), original findings showing the association of the angiotensin-II receptor type-2 gene (AGTR2) rs11091046 A>C polymorphism with athlete status. We compared genotypic frequencies of the AGTR2 rs11091046 polymorphism among 282 track and field sprint/ power athletes (200 men and 82 women), including several national record holders and Olympic medallists (214 Japanese, 68 Russian and Polish), and 2024 control subjects (842 men and 1182 women) (804 Japanese, 1220 Russian and Polish). In men, a meta-analysis from the two combined cohorts showed a significantly higher frequency of the C allele in athletes than in controls (odds ratio: 1.62, P=0.008, heterogeneity index I²=0%). With regard to respective cohorts, C allele frequency was higher in Japanese male athletes than in controls (67.7% vs. 55.9%, P=0.022), but not in Russian/Polish male athletes (61.9% vs. 51.0%, P=0.172). In women, no significant results were obtained by meta-analysis for the two cohorts combination (P=0.850). The AC genotype frequency was significantly higher in Russian/Polish women athletes than in controls (69.2% vs. 42.1%, P=0.022), but not in Japanese women athletes (P=0.226). Our results, in contrast to previous findings, suggested by meta-analysis that the C allele of the AGTR2 rs11091046 polymorphism is associated with sprint/power track and field athlete status in men, but not in women. [ABSTRACT FROM AUTHOR]

Published
2018
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13. The polygenic profile of Russian football players

Author

Egorova, Emiliya S., primary, Borisova, Alyona V., additional, Mustafina, Leysan J., additional, Arkhipova, Alina A., additional, Gabbasov, Rashid T., additional, Druzhevskaya, Anastasiya M., additional, Astratenkova, Irina V., additional, and Ahmetov, Ildus I., additional

Published
2014
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