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108 results on '"Effert, R."'

4. Ophthalmoneurology

Author

Kömpf, D., Fetter, M., Tweed, D., Koenig, E., Thier, P., Dichgans, J., Mergner, Th., Maurer, Ch., Becker, W., Fischer, D., Misslisch, H., Härtung, Hans-Peter, Toyka, Klaus V., Büttner, Th., Kuhn, W., Klotz, P., Steinberg, R., Langkafel, M., Przuntek, H., Wöbker, G., Cramer, S., Ferbert, A., Konstanzer, A., Ceballos-Baumann, A.-O., Kornhuber, M., Dressnandt, J., Conrad, B., Erbguth, F., Hilz, M.-J., Kilian, K.-D., Rechlin, Th., Claus, D., Neundörfer, B., Klostermann, W., Verleger, R., Heide, W., Wauschkuhn, B., Seyfert, T., Mierisch, C., Moser, A., Matzke, M., Heinze, H. J., Dorfmüller, G., Münte, T. F., Dietz, H., Masur, H., Papke, K., Oberwittler, C., Müller, M., Kessler, Ch., Wessel, K., Mehdorn, E., Baez, K. A., Hamann, G., Höh, H., Ruprecht, K. W., Schumacher, M., Schmidt, D., Wakhloo, A. K., Wittich, I., Klingelhöfer, J., Matzander, G., Lagrèze, H. L., Hartmann, A., Anzinger, G., Petrovici, J.-N., Niklaus, K., Schulz, J. B., Klockgether, T., Faiss, J., Rosengart, A., Kaplan, R. F., Hedges, T. R., Eisner, A. E., Caplan, L. R., Barry, J. C., Effert, R., Kaupp, A., Jerusalem, F., Nüssgens, Z., Roggenkämper, P., Wittkämper, A., Wilhelm, H., Schierer, U., Zrenner, E., Kölmel, Hans W., Schoepf, Dieter, Zangemeister, W. H., Collmann, H., Sörensen, N., Krauß, J., Sold, J., Mühling, J., and Schimrigk, K.

Published
1992
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10. 3-year results of the German nationwide survey on eye injuries caused by fireworks

Author

Gabel-Pfisterer, A., Boehringer, D., Agostini, H., Fuest, M., Walter, P., Botros, Y., Mueller, A., Al-Ashi, N., Lenglinger, M., Mueller, B., Schoenfeld, S., Seibel, I., Joussen, A., Breuss, H., Kuchenbecker, J., Foerster, M. H., Berthold, A., Wirbelauer, C., Hofmayer, H., Wachtlin, J., Palka, K., Niemeyer, M., Walla, T., Pham, D., Aisenbrey, S., Tatsiou, A., Walch, A., Burk, R., Schultz, T., Tsiampalis, N., Rehmann, J., Sliwowska, U., Schojai, M., Schulze, K., Kamguia, N., Wirtz, C., Dick, B., Voelker, D., Wintergerst, M., Pfau, M., Melzer, C., Hoegen, D., Bosch, F., Andresen, J. C., Krohne, T., Holz, F., Kathke, M., Sturm, A., Noske, W., Huebner, T., Brandner, S., Feldmann, M., Morsek, J., Rainer, O., Bartsch, H., Ewald, K., Chankiewitz, E., Siegmund, T., Bohlen, A., Mohr, A., Hecker, J., Strassburger, P., Furashova, O., Engelmann, K., Krieb, A., Emmerich, K., Grajewski, L., Krause, L., Jabur, A., Ruediger, K., Lehmann, F., Sachs, H., Matthee, E., Steindorf, F., Schnitzler, C., Neumann, I., Korbmacher, J., Geerling, G., Doulgkeridis, J., Erhard, J., Dahms-Dowidat, K., Kotiasvili, T., Jagow, B. V., Lieder, A., Blum, M., Westerkemper, H., Boehm, M., Bornfeld, N., Bechrakis, N., Schultheiss, M., Scheider, A., Mueller, M., Kohnen, T., Eckert, T., Eckardt, C., Wisniewska, M., Just, A., Jehle, V., Reinhard, T., Seewald, J., Mais, C., Basiakos, S., Osman, B., Xanthopoulou, E., Friedburg, B., Graef, M., Lorenz, B., Just, U., Naxer, S., Oterendorp, C., Bemme, S., Callizo, J., Feltgen, N., Hoerauf, H., Menges, A., Tost, F., Stahl, A., Huth, A., Viestenz, A., Bertram, P., Skevas, C., Kromer, R., Casagrande, M., Grohmann, C., Mehlan, J., Schindler, P., Spitzer, M., Schargus, M., Eddy, M., Schumacher, S., Keserue, M., Scheler, A., Stemplewitz, B., Schaudig, U., Abou Moulig, W., Framme, C., Rosenthal, A., Hesse, L., Kunz, L., Spira, C., Suffo, S., Seitz, B., Wietstock, G., Augsten, R., Meller, D., Mayer, M., Vanselow, K., Lieb, W., Beutner, A., Effert, R., Ehlken, C., Roider, J., Hueber, A., Cursiefen, K., Schrage, N., Kroeger, M., Viehweg, N., Meier, P., Unterlauft, J. D., Wiedemann, P., Hattenbach, L., Kakkassery, V., Ranjbar, M., Mohi, A., Grisanti, S., Bastron, I., Sarac, S., Kaskel-Paul, S., Stoffelns, B., Schuster, A., Pfeiffer, N., Schulze, S., Praskevas, A., Sekundo, W., Weigel, M., Thieme, H., Wolf, A., Vounotrypidis, E., Priglinger, S., Bechstein, L., Maier, M., Lohmann, C., Haritoglu, C., Alten, F., Eter, N., Klishko, V., Holland, U., Medra, A., Weber, A., Hoeh, H., Schmidbauer, J., RiveraGomez, C., Plantzas, K., Weiss, M., Hille, K., Hoehn, F., Schrader, M., Napholz, A., Tandogan, T., Walter, C., Zuehlsdorff-Uthke, M., Liekfeld, A., Blecha, C., Barth, T., Helbig, H., Juenemann, A., Decker, A., Kuehn, M., Ladewig, M., Lenhard, K., Lackner, B., Gekeler, F., Holzschuh, I., Boden, K. T., Szurmann, P., Faul, D., May-Endres, K., Press, U., Luttke, J., Ziemssen, F., Bartz-Schmidt, U., Cordes, J., Raber, F., Mikielewicz, M., Kammerer, J., Kupferschmid, S., Buchwald, H., Werner, J., Kampmeier, J., Bula, A., Krauss, P., Strzalkowski, P., Hillenkamp, J., Gabel-Pfisterer, A., Boehringer, D., Agostini, H., Fuest, M., Walter, P., Botros, Y., Mueller, A., Al-Ashi, N., Lenglinger, M., Mueller, B., Schoenfeld, S., Seibel, I., Joussen, A., Breuss, H., Kuchenbecker, J., Foerster, M. H., Berthold, A., Wirbelauer, C., Hofmayer, H., Wachtlin, J., Palka, K., Niemeyer, M., Walla, T., Pham, D., Aisenbrey, S., Tatsiou, A., Walch, A., Burk, R., Schultz, T., Tsiampalis, N., Rehmann, J., Sliwowska, U., Schojai, M., Schulze, K., Kamguia, N., Wirtz, C., Dick, B., Voelker, D., Wintergerst, M., Pfau, M., Melzer, C., Hoegen, D., Bosch, F., Andresen, J. C., Krohne, T., Holz, F., Kathke, M., Sturm, A., Noske, W., Huebner, T., Brandner, S., Feldmann, M., Morsek, J., Rainer, O., Bartsch, H., Ewald, K., Chankiewitz, E., Siegmund, T., Bohlen, A., Mohr, A., Hecker, J., Strassburger, P., Furashova, O., Engelmann, K., Krieb, A., Emmerich, K., Grajewski, L., Krause, L., Jabur, A., Ruediger, K., Lehmann, F., Sachs, H., Matthee, E., Steindorf, F., Schnitzler, C., Neumann, I., Korbmacher, J., Geerling, G., Doulgkeridis, J., Erhard, J., Dahms-Dowidat, K., Kotiasvili, T., Jagow, B. V., Lieder, A., Blum, M., Westerkemper, H., Boehm, M., Bornfeld, N., Bechrakis, N., Schultheiss, M., Scheider, A., Mueller, M., Kohnen, T., Eckert, T., Eckardt, C., Wisniewska, M., Just, A., Jehle, V., Reinhard, T., Seewald, J., Mais, C., Basiakos, S., Osman, B., Xanthopoulou, E., Friedburg, B., Graef, M., Lorenz, B., Just, U., Naxer, S., Oterendorp, C., Bemme, S., Callizo, J., Feltgen, N., Hoerauf, H., Menges, A., Tost, F., Stahl, A., Huth, A., Viestenz, A., Bertram, P., Skevas, C., Kromer, R., Casagrande, M., Grohmann, C., Mehlan, J., Schindler, P., Spitzer, M., Schargus, M., Eddy, M., Schumacher, S., Keserue, M., Scheler, A., Stemplewitz, B., Schaudig, U., Abou Moulig, W., Framme, C., Rosenthal, A., Hesse, L., Kunz, L., Spira, C., Suffo, S., Seitz, B., Wietstock, G., Augsten, R., Meller, D., Mayer, M., Vanselow, K., Lieb, W., Beutner, A., Effert, R., Ehlken, C., Roider, J., Hueber, A., Cursiefen, K., Schrage, N., Kroeger, M., Viehweg, N., Meier, P., Unterlauft, J. D., Wiedemann, P., Hattenbach, L., Kakkassery, V., Ranjbar, M., Mohi, A., Grisanti, S., Bastron, I., Sarac, S., Kaskel-Paul, S., Stoffelns, B., Schuster, A., Pfeiffer, N., Schulze, S., Praskevas, A., Sekundo, W., Weigel, M., Thieme, H., Wolf, A., Vounotrypidis, E., Priglinger, S., Bechstein, L., Maier, M., Lohmann, C., Haritoglu, C., Alten, F., Eter, N., Klishko, V., Holland, U., Medra, A., Weber, A., Hoeh, H., Schmidbauer, J., RiveraGomez, C., Plantzas, K., Weiss, M., Hille, K., Hoehn, F., Schrader, M., Napholz, A., Tandogan, T., Walter, C., Zuehlsdorff-Uthke, M., Liekfeld, A., Blecha, C., Barth, T., Helbig, H., Juenemann, A., Decker, A., Kuehn, M., Ladewig, M., Lenhard, K., Lackner, B., Gekeler, F., Holzschuh, I., Boden, K. T., Szurmann, P., Faul, D., May-Endres, K., Press, U., Luttke, J., Ziemssen, F., Bartz-Schmidt, U., Cordes, J., Raber, F., Mikielewicz, M., Kammerer, J., Kupferschmid, S., Buchwald, H., Werner, J., Kampmeier, J., Bula, A., Krauss, P., Strzalkowski, P., and Hillenkamp, J.

Abstract

Background On festive days worldwide eyes are severely injured by fireworks. The data on the number and severity are to date not registered in Germany. Objective How frequent are firework-induced injuries in Germany, who are the affected, how serious are the injuries, which forms of treatment are necessary and how frequent are accompanying injuries? Method A German nationwide online-based survey was carried out in all inpatient eye departments and data over the last 3 consecutive years were descriptively analyzed. Results From New Years Eve 2016/2017, when 41 eye departments sent in data, the participation could be increased to 51 eye departments in 2018/2019. More than one third (33-39%) of all 1356 patients over 3 years were minors, 60% were younger than 25 years old and roughly 60% of patients were injured as bystanders or in an unclear situation. In total 25% of all eye injuries were considered severe and required inpatient treatment. Accompanying injuries of the other eye, the face and hands were more frequent in minors than in adults. Eyeball ruptures were reported in 10 minors and 38 adults over the 3 years. Conclusion Particularly minors and bystanders need better protection.

Published
2019

14. Neues automatisiertes Verfahren zur Messung des Lesevermögens im Rahmen einer Anti-VEGF-Therapie

Author

Effert, R and Flöter, C

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Während einer Anti-VEGF-Therapie ist nicht nur die zentrale Sehschärfe von Interesse, sondern auch das Lesevermögen. Das Lesevermögen wird in der Praxis aber in der Regel nicht getestet. Wir präsentieren ein neues Verfahren zur standardisierten Messung des Lesevermögens.[zum vollständigen Text gelangen Sie über die oben angegebene URL], 29. Jahrestagung der Retinologischen Gesellschaft

Published
2016
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17. Automatisierte Messung der zentralen Sehschärfe und des Lesevermögens nach Anti-VEGF-Therapie: Klinische Erfahrungen

Author

Effert, R, Göbel, C, and Wernhardt, J

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Die zentrale Sehschärfe ist ein wesentlicher Parameter zur Beantwortung der Frage ob eine Anti-VEGF-Therapie begonnen oder fortgesetzt werden soll. Um so wichtiger ist die exakte Messung. Im letzten Jahr haben wir eine auf iPads basierten automatisierten Methode zur Messung des Visus vorgestellt.[for full text, please go to the a.m. URL], 87. Versammlung des Vereins Rhein-Mainischer Augenärzte

Published
2014
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18. Histomorphologische Stadieneinteilung des infiltrativen Wachstums in der Aderhaut beim Retinoblastom

Author

Effert R, H Schilling, H Yang, and A Wessing

Subjects
Pathology, medicine.medical_specialty, Retinal pigment epithelium, Retinoblastoma, Tumor cells, Biology, medicine.disease, eye diseases, Sclera, medicine.anatomical_structure, Management of Technology and Innovation, medicine, Neoplasm staging, sense organs, Choroid, Infiltration (medical), Blood vessel
Abstract

In order to inquire into standard for morphologic classification of choroidal invasion of retinoblastoma and to study the tumor clinic--pathologic further under the integrated scale, the changes of retinal pigment epithelium, Bruch's membrane and choroid on the histopathological sectins of 297 cases of primary enucleated eyes of retinoblastoma were retrospectively observed under the light microscopy. The choroidal invasion was morphologically divided into four stages: Stage 1, only retinal pigment epithelium involved, the Bruch's membrane was intact; Stage 2, the Bruch's membrane was destroyed and the choroidal capillaris was not infiltrated; Stage 3, choroial capillary and middle blood vessel layer in small limits were infiltrated; Stage 4, invasion involved in choroid in great limits and involvement of sclera existed simultaneously. This classification (also called pigment epithel--choroid stage, PEC--stage) reflected both infiltrated procedure of tumor cells and preventive mechanism in eye and morphological criterion half--quantitatively. It can be used as a united standard to compare the infiltration degree of retinoblastoma among different individuals and different studies.

Published
1999

19. Standardisierte Testung des Sehvermögens

Author

Effert, R.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Die intravitreale Injektion von AntiVEGF Faktoren ist die einzige Therapieform, mit der es gelingt den Krankheitsprozess einer Altersbedingten Makuladegeneration (AMD) aufzuhalten. Häufig wird sogar eine Verbesserung der zentralen Sehschärfe erreicht . Es zeichnet sich ab, dass in vielen[for full text, please go to the a.m. URL], 86. Versammlung der Vereinigung Rhein-Mainischer Augenärzte

Published
2013

20. Programm zur Erfassung und Dokumentation von Behandlungsdaten bei intravitrealen Injektionen

Author

Beutner, A, Lindwurm, M, and Effert, R

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die intravitreale Injektion ist eine Standardtherapie bei vielen Erkrankungen der Netzhaut geworden. Nach wie vor ist nicht geklärt, wie viele Injektionen definitiv sinnvoll sind. Insofern sollte jede behandelnde Abteilung eine eigene Qualitätskontrolle einrichten. Methode:[for full text, please go to the a.m. URL], 83. Versammlung der Vereinigung Rhein-Mainischer Augenärzte

Published
2010
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22. Extrakapsuläre Kataraktextraktion mit Phakoemulsifikation und Pars-Plana-Vitrektomie mit Silikonöltamponade in einer Sitzung

Author

Effert R

Subjects
Intraocular pressure, Silicon oil, medicine.medical_specialty, Visual acuity, genetic structures, business.industry, medicine.medical_treatment, Intraocular lens, Vitrectomy, Phacoemulsification, Cataract surgery, eye diseases, Surgery, Ophthalmology, medicine.anatomical_structure, Lens (anatomy), medicine, sense organs, medicine.symptom, business
Abstract

BACKGROUND: In phacic eyes the development of a cataract is induced by silicon oil. In this case the lens has to be removed in a second operation with or without intraocular lens implantation. In cataract surgery a new incision technique is used, which makes it easily possible to combine both operations in one session. METHODS: A feature of the new incision technique is that a scleral tunnel is dissected before the anterior chamber is opened. The opening closes itself, if the intraocular pressure rises. The danger, that a rise in intraocular pressure during the vitrectomy makes an irisprolaps, for example during the substitution of perfluorcarbon by silicon oil, no longer exists. RESULTS: The operation technique and the postoperative course of three patients with intraocular lens implantation and pars-plana-vitrectomy using silicon oil is reported. CONCLUSIONS: By using the new incision technique in cataract surgery intraoperative complications during vitrectomy like an irisprolaps or penetration of silicon oil into the anterior chamber no longer exist. In selected cases one operation is saved for the patient.

Published
1992

27. Protrusio bulbi, V.a. retrobulbären Gefäßprozess

Author

Kuhn Fp, Truss J, Effert R, and Rudolph O

Subjects
medicine.medical_specialty, Vascular disease, business.industry, Arterial disease, Fistula, Eye disease, medicine.disease, Ophthalmology, medicine.anatomical_structure, Cavernous sinus, medicine, business, Vein, Venous disease, Process (anatomy)
Published
2000

39. Ein alternatives Meßverfahren zum Simultan-Prismen-Covertest

Author

Effert R

Subjects
Physics, genetic structures, business.industry, Simultaneous prism-cover test, eye diseases, Pupil, Collimated light, Optical axis, Ophthalmology, Optics, Light source, Fixation (visual), Minimum deviation, sense organs, business, Visible spectrum
Abstract

The simultaneous prism cover test is frequently used for measuring a manifest squint angle. In this paper an alternative method for measuring a manifest squint angle is described. While a subject fixes on a fixation object in near or far position, one eye illuminated from below with a collimated visible light beam. The light source is mounted on a holder which can be rotated around a vertical axis. The examiner observes the light reflexes of the anterior surface of the cornea and the posterior surface of the lens in the patients pupil and turns the holder until the images lie on a vertical line. In this case the direction of the incident light beam, which is determined by the position of the holder, and the direction of the optical axis of the eye coincide. For example, by measuring before and after covering, the difference in the measured light directions is the manifest squint angle, as determined by the simultaneous prism cover test.

Published
1989

40. [Clinical use of the Canon R10 autorefractometer for determining refraction in children with strabismus]

Author

Hunold W, Gerd Auffarth, and Effert R

Subjects
Strabismus, Adolescent, Microcomputers, Computers, Child, Preschool, Accommodation, Ocular, Astigmatism, Humans, Child, Refraction, Ocular, Retina
Abstract

Using a Canon R 10 Autofractor, refraction was measured in 131 children with squint. Measurements before and after cycloplegia were compared to a reference measurement (taken with the Rodenstock PR 50 hand-held refractometer after cycloplegia). In 80% of the cases the power and axis of the cylinder equalled the reference measurements. Due to accommodation, 40% of the values for spherical equivalents before cycloplegia were false. After cycloplegia 80% of the spherical equivalents were also in agreement with the reference measurement. The short examination time and the interesting fixation target facilitate multiple measurements in children. As a result, refraction can be measured more reliably with the R 10 Autorefractor than with the hand-held refractometer in children from age 2 1/2 or 3. Retinoscopy is only indispensable in cases where it is difficult or impossible to use an autorefractor, i.e., on children aged under 2 1/2 and those with extreme head tilt.

47. Pandemiebedingtes Verkaufsverbot von Feuerwerkskörpern in Deutschland führt zu einer deutlichen Abnahme der Augenverletzungen

Author

Gabel-Pfisterer, Ameli, Böhringer, Daniel, Agostini, Hansjürgen, Feuerwerks-Verletzungen-Studiengruppe, Botros, Y., Krieb, A., Emmerich, K.-H., Grajewski, L., Krause, L., Hoa, D. Q., Yilmaz, S., Jabur, A., Rüdiger, K., Boeker, T., Rashitova, D., Eberlein, G., Lehmann, F., Sachs, H., Matthee, E., Pillunat, L., Juergens, L., Kaya, S., Guthoff, R., Steindorf, F., Korbmacher, J., Geerling, G., Märtz, J., Widder, R., Rössler, G., Iseed, A., Doulgkeridis, J., Erhard, J., Tomalla, M., von Jagow, B., Filev, F., Schill, S., Kotiasvili, T., Kojetinski, C., Flach, A., Zollfrank, C., Lieder, A., Blum, M., Tourtas, T., Knorr, H., Kruse, F., Freimuth, M., Dalbah, S., Sokolenko, E., Mueller, A., Rating, P., Kiefer, T., Book, B., Westerkemper, H., Böhm, M., Bornfeld, N., Bechrakis, N., Schultheiss, M., Scheider, A., Pawlowczicz, K., Hagenbusch, J., Müller, M., Kohnen, T., Ahdab, K., Eckert, T., Eckardt, C., Wisniewska, M., Just, A., Laich, Y., Stifter, J., Avar, M., Gritzka, M., Jehle, V., Reinhard, T., Rab, S., Seewald, J., Mais, C., Basiakos, S., Osman, B., Xanthopoulou, E., Friedburg, B., Graef, M. H., Dempe, C., Lorenz, B., Just, U., Schrecker, J., Klemming, J., Drüke, D., Bemmer, L., Weiß, S., Take, P., Nguyen-Höhl, A., Oterendorp, C., Al-Ashi, N., Feltgen, N., Hoerauf, H., Prusiecki, I., Elle, J., Gundel, B., Bender, M. C., Menges, A., Tost, F., Stahl, A., Wienrich, R., Breuß, H., Huth, A., Viestenz, A., Ueberschaar, J., Daehn, T., Brooks, U., Schindler, P., Bigdon, E., Bertram, P., Skevas, C., Kromer, R., Kuchenbecker, J., Casagrande, M., Grohmann, C., Mehlan, J., Spitzer, M., Schargus, M., Eddy, M., Schumacher, S., Keserü, M., Scheler, A., Foerster, M. H., Stemplewitz, B., Schaudig, U., Herden, J., Haar, M., Tode, B., Junker, B., Abou Mouli, W., Volkmann, I., Framme, C., Scheuerle, A., Seibel, I., Auerbach, M., Beisse, C., Rohrschneider, K., Auffahrt, G., Mala, N., Rosenthal, A., Hesse, L., Daas, L., Flockerzie, E., Suffo, S., Böker, A., Seitz, B., Chrisoglou, N., Wietstock, G., Augsten, R., Meller, D., Althauspetervari, I., Rudolph, O., Floeter, C., Beutner, A., Effert, R., Greve, D., Mayer, M., Vanselow, K., Lieb, W., Kandzia, C., Purtskhvanidze, K., Ehlken, C., Roider, J., Hueber, A., Cursiefen, K., Edelmann, C., Lenglinger, M., Schrage, N., Kroeger, M., Viehweg, N., Meier, P., Unterlauft, J. D., Wiedemann, P., Rehak, M., Ziemssen, F., Rommel, F., Sonntag, S., Müller, B., Prasuhn, M., Pawlik, V., Kakkassery, V., Ranjbar, M., Mohi, A., Grisanti, S., Bastron, I., Dindin-Sarac, S., Kaskel-Paul, S., Rawohl, J., Schönfeld, S., Hattenbach, L., Stoffelns, B., Schuster, A., Pfeiffer, N., Besgen, V., Schröder, F., Schulze, S., Weber, N., Sekundo, W., Schuart, C., Renieri, G., Weigel, M., Thieme, H., Hagenau, F., Wolf, A., Vounotrypidis, E., Priglinger, S., Penkava, J., Klein, J., Bechstein, L., Joussen, A., Maier, M., Lohmann, C., Haritoglu, C., Alten, F., Eter, N., Brinkmann, C., Alshikh, F., Klishko, V., Holland, U., Medra, A., Kolarov, D., Weber, A., Höh, H., Pielen, A., Zschockelt, T., Luciani, F., Schmidbauer, J., Horn, P., Kodomskoi, L., Kuempel, H., Schwarz, P., Rivera Gomez, C., Plantzas, K., Weiss, M., Hille, K., Esper, G., Mazko, K., Kolbeck, L., Malek, S., Kupper, P., Grafmueller, S., Puk, C., Schrader, S., Darawsha, R., Bellios, N., Wulff, V., Ghaffary, A., Ghoreishi, A., Höhn, F., Napholz, A., Tandogan, T., Schmidt, L., Berthold, A., Ilski, P., Trossowski, C., Zühlsdorff-Utke, M., Liekfeld, A., Winter, I., Böhm, A., Blecha, C., Barth, T., Helbig, H., Rusch, W., Wirbelauer, C., Noerenberg, A., Juenemann, A., Fuchsluger, T. A., Matar, C., Zuche, M., Roehrig, S., Decker, A., Kühn, M., Ladewig, M., Schmidt-Wetter, J., Hofmayer, H., Machulla, R., Boateng, A.-F., Dias Blak, M., Krawczyk, S., Lenhard, K., Lackner, B., Gekeler, F., Mamacek, D., Wocker, L., Holzschuh, I., Wachtlin, J., Boden, K. T., Szurmann, P., Faul, D., May-Endres, K., Press, U., Luttke, J., Wolfram, L., Reichel, F., Seitz, I., Bartz-Schmidt, U., Speidel, A., Cordes, J., Raber, F., Mikielewicz, M., Kammerer, J., Kupferschmid, S., Buchwald, H., Werner, J., Meyer, J. F., Kampmeier, J., Dithmar, S., Fischer, G., Pruefke, C., Bula, A., Krauß, P., Strzalkowski, P., Hillenkamp, J., Macher, T., Kuerten, D., Palka, K., Niemeyer, M., Walla, T., Pham, D., Aisenbrey, S., Rieck, P., Verbeck, J., Tatsiou, A., Walch, A., Burk, R., Fuest, M., Schnober, G., Elling, M., Schultz, T., Tsiampalis, N., Rehmann, J., Sliwowska, U., Schojai, M., Schulze, K., Kamguia, N., Wirtz, C., Walter, P., Dick, B., Bourauel, L., Schützeichel, F. 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Abstract

Die Ophthalmologie 119(12), 1257-1266 (2022). doi:10.1007/s00347-022-01778-1, Published by Springer Medizin, Berlin ; Heidelberg

Published
2022

49. [A clinicopathological study of 297 cases of retinoblastoma].

Author

Yang H, Schilling H, Effert R, and Wessing A

Subjects
Adolescent, Adult, Child, Child, Preschool, Female, Humans, Infant, Male, Neoplasm Invasiveness, Neoplasm Staging, Choroid pathology, Pigment Epithelium of Eye pathology, Retinal Neoplasms pathology, Retinoblastoma pathology
Abstract

Objective: To find a morphological criterion of classification for choroidal invasion of retinoblastoma in order to further study clinical pathology of retinoblastoma (Rb) under an integrate rule., Methods: The changes of retinal pigment epithelium, Bruch's membrane and choroid on histopathological sections of primarily enucleated eyes with Rb in 297 cases were observed under a light microscope., Results: The globe wall invasion could be morphologically divided into four stages (briefly pigment epithelium-choroid classification). Stage I: Only retinal pigment epithelium was infiltrated, the Bruch's membrane was intact. Stage 2.: The Bruch's membrane was destructed, but the choriocapillaries were not invaded. Stage 3: The invasion reached middle choroidal blood vessels close to the choriocapillaris in a limited scope. Stage 4: Massive choroidal infiltration of all choroidal layers existed and the sclera could be simultaneously involved. The mortality for stage 4 was 11.5% and for stage 1 to 3 was 0.4%., Conclusion: The pigment epithelium-choroid stage (PEC-stage) classification in our study can be used as an integrate rule to compare the invasion degree of retinoblastoma in different individuals and studies.

Published
1999

50. [Morphologic classification of choroidal invasion of retinoblastoma].

Author

Yang H, Schilling H, Effert R, and Wessing A

Subjects
Adolescent, Child, Choroid Neoplasms classification, Female, Humans, Male, Neoplasm Invasiveness, Neoplasm Staging, Retrospective Studies, Choroid Neoplasms pathology, Eye Neoplasms pathology, Retinoblastoma pathology
Abstract

In order to inquire into standard for morphologic classification of choroidal invasion of retinoblastoma and to study the tumor clinic--pathologic further under the integrated scale, the changes of retinal pigment epithelium, Bruch's membrane and choroid on the histopathological sectins of 297 cases of primary enucleated eyes of retinoblastoma were retrospectively observed under the light microscopy. The choroidal invasion was morphologically divided into four stages: Stage 1, only retinal pigment epithelium involved, the Bruch's membrane was intact; Stage 2, the Bruch's membrane was destroyed and the choroidal capillaris was not infiltrated; Stage 3, choroial capillary and middle blood vessel layer in small limits were infiltrated; Stage 4, invasion involved in choroid in great limits and involvement of sclera existed simultaneously. This classification (also called pigment epithel--choroid stage, PEC--stage) reflected both infiltrated procedure of tumor cells and preventive mechanism in eye and morphological criterion half--quantitatively. It can be used as a united standard to compare the infiltration degree of retinoblastoma among different individuals and different studies.

Published
1999
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