103 results on '"Effective model"'
Search Results
2. Drag Computation on Rough Surfaces Using a Homogenised Model
- Author
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Sudhakar, Y., Jain, Sahaj, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Singh, Krishna Mohan, editor, Dutta, Sushanta, editor, Subudhi, Sudhakar, editor, and Singh, Nikhil Kumar, editor
- Published
- 2024
- Full Text
- View/download PDF
3. Edge Matrices of Magnetic Sector in a Static Mass Spectrometer.
- Author
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Sachenko, V. D. and Antonov, A. S.
- Subjects
- *
TRANSFER matrix , *MAGNETIC ions , *MAGNETIC fields , *CONSERVATION laws (Physics) - Abstract
The first-order input and output edge transfer matrix elements of the magnetic sector in a static mass spectrometer are derived based on the conservation law of the generalized momentum of ions in a magnetic field. The structure of the edge matrix is shown to be ambiguous and dependent on the effective model, which considers the displacement of ion trajectories in the edge field. A comparison of the results obtained with traditional methods, such as expanding the edge field components and trajectory equations into asymptotic series and integrating successive approximations, reveals significant differences in the first-order edge matrix elements in the effective model of the magnetic sector, where the ideal uniform field is bounded by Herzog boundaries, compared to the published data. Algorithms for matching the input and output axes of the magnetic sector, taking into account the action of the edge fields, are given. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
4. Model for Effective Project Implementation for Undergraduate Students
- Author
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Yalagi, Pratibha S., Chavan, Vishwanath D., Gandhamal, Dattatray P., Howlett, Robert J., Series Editor, Jain, Lakhmi C., Series Editor, Choudrie, Jyoti, editor, Mahalle, Parikshit N., editor, Perumal, Thinagaran, editor, and Joshi, Amit, editor
- Published
- 2023
- Full Text
- View/download PDF
5. A Beyond Mean Field Approach to Yang-Mills Thermodynamics
- Author
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Singha, Pracheta, Ray, Rajarshi, Aminul Islam, Chowdhury, Mustafa, Munshi G, Mohanty, Bedangadas, editor, Swain, Sanjay Kumar, editor, Singh, Ranbir, editor, and Kashyap, Varchaswi K. S., editor
- Published
- 2022
- Full Text
- View/download PDF
6. Understanding Machine Learning Through Data-Oriented and Human Learning Approaches
- Author
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Behpour, Sahar, Udash, Avi, Spector, J. Michael, Series Editor, Bishop, M.J., Series Editor, Ifenthaler, Dirk, Series Editor, Yuen, Allan, Series Editor, Albert, Mark V., editor, Lin, Lin, editor, Spector, Michael J., editor, and Dunn, Lemoyne S., editor
- Published
- 2022
- Full Text
- View/download PDF
7. Summary and Outlook
- Author
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Yanagihara, Ryosuke and Yanagihara, Ryosuke
- Published
- 2021
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- View/download PDF
8. Introduction
- Author
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Yanagihara, Ryosuke and Yanagihara, Ryosuke
- Published
- 2021
- Full Text
- View/download PDF
9. Proposing an Effective Model for Improving Integration the Medical Education System with Health Services at Iran's Ministry of Health and Medical Education
- Author
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Abdolreza Gilavand, Yadollah Mehralizadeh, Mohammad Hosseinpour, and Amin Torabipour
- Subjects
integration ,medical education system ,health services ,effective model ,iran ,Nursing ,RT1-120 ,Medicine (General) ,R5-920 - Abstract
Background: In Iran, the medical education system was integrated with the healthcare provision system in 1985 and finally, it led to the creation of a new ministry titled “Ministry of Health and Medical Education”. Regarding this integration has created some problems, the current study intended to provide an effective pattern for improvement of this integration. Methods: The present study is both fundamental and applied in terms of objective. The statistical population of the client study included all of the managers, faculty members and experts in the universities of medical sciences in Khuzestan Province, in southwestern Iran, who were chosen by the use of full census sampling. Finally, 103 people filled in the questionnaires. The data collection instrument was a researcher-devised questionnaire. The data analysis was done by SPSS Ver.24, the descriptive statistics (percentage, mean, and standard deviation), and the inferential statistics (Pearson Correlation Test). Results: In order to increase the effectiveness of this integration, four scenarios were suggested among which, finally “the separation of the medical education from the medical sciences universities and placing under direct supervision of the Minister of Health and Medical Education” with 3.84 (based on a maximum score of 4) achieved the highest score. Based on this score, a model based on the upstream laws of Iran was designed and suggested and in each province, instead of having a unit and independent institution under the title of the university of medical sciences and healthcare services, two separate institutions as “The Provincial University of Medical Sciences” and “The Provincial Health Service Organization” would be created and would work under the supervision of Minister of Health and Medical Education. Conclusion: The results of this study showed that medical education in the health ministry supervised universities is affected by the discussions of the provision of the health and medical care provision. Therefore, to realize it and improve the educational tasks, production of knowledge, and conducting of research in the universities, and protecting it from other departments, an effective pattern has been suggested.
- Published
- 2021
- Full Text
- View/download PDF
10. The non-linear supersymmetric hyperbolic sigma model on a complete graph with hierarchical interactions.
- Author
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Disertori, Margherita, Merkl, Franz, and Rolles, Silke W. W.
- Subjects
- *
GRAPH theory , *LOGARITHMIC functions , *NONLINEAR analysis , *SUPERSYMMETRY , *HYPERBOLIC geometry - Abstract
We study the non-linear supersymmetric hyperbolic sigma model H2/2 on a complete graph with hierarchical interactions. For interactions which do not decrease too fast in the hierarchical distance, we prove tightness of certain spin variables in horospherical coordinates, uniformly in the pinning and in the size of the graph. The proof relies on a reduction to an effective H2/2-model; its size is logarithmic in the size of the original model. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
11. «Tomographic transformation» of anomalous magnetic field using grid distribution of equivalent sources
- Author
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Долгаль А.С., Новикова П.Н., Осипова Е.Н., Пугин А.В., and Рашидов В.А.
- Subjects
interpretation tomography ,effective model ,equivalent source approximation ,magnetic field ,Geology ,QE1-996.5 - Abstract
The article is devoted to the «tomographic» approach to the interpretation of geopotential fields. A brief excursus into the history of the development of interpretational (pseudo-) tomography is given. General issues concerning the creation of «effective» tomographic models are considered. Transformations based on the equivalent source technique are proposed as a key part of the tomography. This type of transformations permits the usage of elevation data of magnetic survey as input. When constructing an analytical approximation, usually a system of linear algebraic equations (SLAE) with an approximated right part is solved. Using a model example, some issues concerning the conditionality of SLAE for different depths of equivalent sources are studied. Two iterative methods for the solving of systems, the Seidel method and the quickest gradient descent, are compared. It is shown that the latter method makes it possible to achieve the required accuracy of the field approximation with a smaller number of iterations. The advantage in the calculation speed, when the matrix of coefficients of the transform operator (source function) is sparce, is emphasized. An example of using this approach to interpret magnetic field anomalies above the submarine volcano 3.18 within the Kuril Iceland arc is presented.
- Published
- 2021
- Full Text
- View/download PDF
12. Application of land properties in estimation of wheat production by FAO and gene expression programming (GEP) models.
- Author
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Bariklo, Ali, Alamdari, Parisa, Moravej, Kamran, and Servati, Moslem
- Abstract
This study aims to compare the Food and Agriculture Organization (FAO) framework as a common model and gene expression programming (GEP) model for predicting the irrigated wheat production by using land properties in Khajeh area, Iran. First, 80 representative soil profiles were described in wheat fields. Then, the soil samples were collected from each horizon, and soil properties were determined in the laboratory for obtaining the model input data. After that, wheat production models were developed by FAO and GEP models. Sensitivity analysis indicated that total N, available P, slope, coarse fragment, electrical conductivity, pH, and organic matter are important soil properties for wheat production. Based on the results, the value of predicted wheat production by GEP model (981–5382) is closer to the actual production (1000–5600) compared to the FAO models (1284–6123). The geometric mean error ratio (GMER), root mean square error (RMSE), and coefficient of determination (R
2 ) between predicted and actual production for FAO and GEP models were calculated 1.24, 18.6, and 0.84 and 0.83, 15.4, and 0.91, respectively. The overall agreement was recognized between wheat predicted production by using FAO and GEP and actual production by composite operator. This agreement was 71.5 and 82.2% for FAO and GEP models, respectively. Therefore, gene expression programming model was introduced as an effective model for predicting the wheat production. This more accuracy was obtained due to good choosing and lack of interaction among land properties as input variables. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
13. The interplay between Fano and Fabry-Pérot resonances in dual-period metagratings.
- Author
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Zhou Hagström, Joar, Maurel, Agnès, and Pham, Kim
- Subjects
- *
FANO resonance , *TRANSMISSION zeros , *SYMMETRY breaking , *INDUCTIVE effect - Abstract
We study theoretically and numerically the occurrence of Fano resonances in a metagrating made of slits with some symmetry breaking resulting in a dual period. At low frequency, a grating composed of long enough slits supports Fabry-Pérot resonances on which Fano resonances superimpose when the grating acquires dual period. The resulting spectrum exhibits flat-banded peaks interrupted by sharp dips with successions of perfect and zero transmissions. To model these scattering properties, homogenization theory is used resulting in an effective problem governing the solutions in the two, non-identical, slits, which are coupled through jump conditions at the grating interfaces. These jumps efficiently encode the effect of the evanescent field able to resonate in the radiative region due to the folding of the spoof plasmon polaritons branches. The model is validated with direct numerics and a local analysis allows us to characterize the resonant mechanisms. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
14. Approaches to the definition of internal financial control
- Author
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D. R. Khabibullina
- Subjects
coso ,cobit ,ternbull rewiev group ,kontrag ,internal financial control ,system of internal control ,effective model ,indicative model ,risk-oriented model ,Business ,HF5001-6182 - Abstract
The article presents an analytical review of Russian and foreign approaches to understanding internal financial control. Different opinions of economists on the methods and tasks of internal financial control have been studied. As the main trend of the study of internal financial control, the strengthening of the role of the system approach is called. The article examines the main domestic models of internal control (indicative, effective, risk-oriented) and provides a comparative analysis of international models of internal control (COSO, COBIT, Ternbull Rewiev Group, KonTraG). The article concluded that it is necessary to increase the effectiveness of the internal control system through a risk-based model. The analysis of approaches to understanding this concept allowed to form a theoretical basis for studying the issues of practical formation of the internal control system.
- Published
- 2020
15. Una revisión de literatura del modelo efectual usando ToS.
- Author
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Casasbuenas Garzón, Jersson and Giraldo Vélez, Laura Patricia
- Subjects
ENTREPRENEURSHIP ,DECISION making ,INSPIRATION ,LOGIC ,VISION ,DIALOGUE - Abstract
Copyright of Económicas CUC is the property of Corporacion Universidad de la Costa, CUC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
16. Proposing ail Effective Model for Improving the Integration of Medical Education System with Health Services at Iran's Ministry of Health and Medical Education.
- Author
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Gilavand, Abdolreza, Mehralizadeh, Yadollah, Hosseinpour, Mohammad, and Torabipour, Amin
- Subjects
- *
MEDICAL education , *SCHOOL integration , *MEDICAL care , *MEDICAL sciences , *POPULATION statistics - Abstract
Background: In In, the medical education system was integrated with the healthcare provision system in 1985 and this was led to the creation of a new ministry titled "Ministry of Health and Medical Education". Regarding this integration, some problems were emerged. Therefore, the current study intended to provide an effective pattern for improvement of this integration. Methods: The present study is both fundamental and applied in terms of its objectives. The statistical population of the client study included all of the managers, feculty members, and experts in the universities of medical sciences in Khuzestan Province, in Southwest Inn, who were chosen by the use of foil census sampling. Finally, 103 participants filled in the questionnaires. The data collection instrtiment was a researcher-devised questionnaire. The data analysis was done by SPSS Ver. 24, the descriptive statistics (percentage, mean, and standard deviation), and the inferential statistics (Pearson Correlation Test). Results: In order to increase the effectiveness of this integration, four scenarios were suggested among which, finally "the separation of the medical education from the medical science universities and placing under direct supervision of the Ministry of Health and Medical Education" with 3.84 (based on a maximum score of 4) achieved the highest score. Based on this score, a model based on the upstream laws of Iran was designed and suggested and in each province, instead of having a tinit and independent instittition under the title of the university of medical sciences and healthcare services, two separate institutions as "The Provincial University of Medical Sciences" and "The Provincial Health Service Organization" would be created and would work under the supervision of Ministry of Health and Medical Education. Conclusion: The results of this sttidy showed that medical education defined by the Ministry of Health is affected by the discussions of medical care provisions. Therefore, to realize it and improve the educational tasks, producing knowledge, conducting research in the universities, and protecting it from other departments, were suggested as effective patterns. [ABSTRACT FROM AUTHOR]
- Published
- 2021
17. A Model on Airborne Radar in Look-Down Search Mode Based on Clutter Spectrum
- Author
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Qi, Dazhi, Pei, Hucheng, Tian, Jinchang, Diniz Junqueira Barbosa, Simone, Series editor, Chen, Phoebe, Series editor, Du, Xiaoyong, Series editor, Filipe, Joaquim, Series editor, Kara, Orhun, Series editor, Kotenko, Igor, Series editor, Liu, Ting, Series editor, Sivalingam, Krishna M., Series editor, Washio, Takashi, Series editor, Zhang, Lin, editor, Song, Xiao, editor, and Wu, Yunjie, editor
- Published
- 2016
- Full Text
- View/download PDF
18. Matrix product state recursion methods for strongly correlated quantum systems
- Author
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Tian, Yifan
- Subjects
Physics ,Condensed matter physics ,Effective Model ,Matrix Product State ,Quantum Many-Body System ,Strongly Correlated System ,Tensor Network ,Time Evolution - Abstract
The main content of this dissertation consists of two projects that I studied during my graduate career. Among them, the first project has more successful results and thus will be the major content of this dissertation. Besides discussing the details of each project, this dissertation also introduces the background knowledge and fundamental techniques of this area.The first project is "recursion methods for strongly correlated quantum system}, which is also the main project". In this project, we present a method for extrapolation of real-time dynamical correlation functions which can improve the capability of matrix product state methods to compute spectral functions. Unlike the widely used linear prediction method, which ignores the origin of the data being extrapolated, our recursion methods utilize a representation of the wavefunction in terms of an expansion of the same wavefunction and its translations at earlier times. This recursion method is exact for noninteracting Fermi system. Surprisingly, the recursion method is also more robust than linear prediction at large interaction strength. We test this method on the Hubbard two-leg ladder, and present more accurate results for the spectral function than previous studies.The second project is "Mapping the Hubbard model to the t-J model using ground state unitary transformations". The effective low-energy models of the Hubbard model are usually derived from perturbation theory. Here we derive the effective model of the Hubbard model in spin space and t-J space using a unitary transformation from numerical optimization. We represent the Hamiltonian as Matrix product state(MPO) and represent the unitary transformation using gates according to tensor network methods. We obtain this unitary transformation by optimizing the unitary transformation between the ground state of the Hubbard model and the projection of the Hubbard model ground state into spin space and t-J space. The unitary transformation we get from numerical optimization yields effective models that are in line with perturbation theories. This numerical optimization method starting from ground state provides another approach to analyze effective low-energy models of strongly correlated electron systems.
- Published
- 2020
19. Modeling grid fields instead of modeling grid cells: An effective model at the macroscopic level and its relationship with the underlying microscopic neural system.
- Author
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Rosay, Sophie, Weber, Simon, and Mulas, Marcello
- Abstract
A neuron's firing correlates are defined as the features of the external world to which its activity is correlated. In many parts of the brain, neurons have quite simple such firing correlates. A striking example are grid cells in the rodent medial entorhinal cortex: their activity correlates with the animal's position in space, defining 'grid fields' arranged with a remarkable periodicity. Here, we show that the organization and evolution of grid fields relate very simply to physical space. To do so, we use an effective model and consider grid fields as point objects (particles) moving around in space under the influence of forces. We reproduce several observations on the geometry of grid patterns. This particle-like behavior is particularly salient in a recent experiment in which two separate grid patterns merge. We discuss pattern formation in the light of known results from physics of two-dimensional colloidal systems. Notably, we study the limitations of the widely used 'gridness score' and show how physics of 2d systems could be a source of inspiration, both for data analysis and computational modeling. Finally, we draw the relationship between our 'macroscopic' model for grid fields and existing 'microscopic' models of grid cell activity and discuss how a description at the level of grid fields allows to put constraints on the underlying grid cell network. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
20. Analysis of the γNΔ and ΔNπ interactions for pion photoproduction.
- Author
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Mariano, A., Barbero, C., Badagnani, D., and Tamayo Agudelo, D.F.
- Subjects
- *
PIONS , *COUPLING constants , *PARTICLES (Nuclear physics) , *MESONS - Abstract
In this paper we analyze for the first time the γN Δ excitation vertex from the point of view of the dynamics of the Δ field, Ψ μ. That is, we look for the value of the Z parameter, present in all contact invariant Δ-field interaction Lagrangians and usually regarded as redundant, and shift it to contact background non-Δ resonant amplitudes (in this sense it is called "redundant") by imposing that the Ψ 0 has no dynamics, instead of readjusting the background coupling constants. We do this within an unitarized model that comprises the Δ-direct amplitude plus background contributions including the Δ-cross term, nucleon Born and meson exchange ones, already implemented in previous works of πN scattering, photo-production and weak- π production. Also we analyze the use of a πN Δ decay vertex interaction containing both first (I 1) and second (I 2) order derivative contributions, as required by renormalization and power counting considerations, in building the γ N → Δ → π N amplitude, in contrast with other works where only I 1 or I 2 is adopted. It is shown that the description of the γ N → π N process, following these prescriptions, is improved. This is a first step: we plan to introduce final state interactions (FSI) in the future, following our previous work in which FCI were introduced using the I 1 interaction alone. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
21. From Real Materials to Model Hamiltonians With Density Matrix Downfolding
- Author
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Huihuo Zheng, Hitesh J. Changlani, Kiel T. Williams, Brian Busemeyer, and Lucas K. Wagner
- Subjects
downfolding ,effective model ,strongly correlated systems ,quantum Monte Carlo ,machine learning ,Physics ,QC1-999 - Abstract
Due to advances in computer hardware and new algorithms, it is now possible to perform highly accurate many-body simulations of realistic materials with all their intrinsic complications. The success of these simulations leaves us with a conundrum: how do we extract useful physical models and insight from these simulations? In this article, we present a formal theory of downfolding–extracting an effective Hamiltonian from first-principles calculations. The theory maps the downfolding problem into fitting information derived from wave functions sampled from a low-energy subspace of the full Hilbert space. Since this fitting process most commonly uses reduced density matrices, we term it density matrix downfolding (DMD).
- Published
- 2018
- Full Text
- View/download PDF
22. Strong-Coupling Expansion and Effective Hamiltonians
- Author
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Mila, Frédéric, Schmidt, Kai Phillip, Lacroix, Claudine, editor, Mendels, Philippe, editor, and Mila, Frédéric, editor
- Published
- 2011
- Full Text
- View/download PDF
23. Kondo effect in the seven-orbital Anderson model hybridized with Γ8 conduction electrons.
- Author
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Hotta, Takashi
- Subjects
- *
KONDO effect , *CONDUCTION electrons , *RENORMALIZATION group , *NUMERICAL analysis , *DEGREES of freedom , *SPIN-orbit interactions - Abstract
We clarify the two-channel Kondo effect in the seven-orbital Anderson model hybridized with Γ 8 conduction electrons by employing a numerical renormalization group method. From the numerical analysis for the case with two local f electrons, corresponding to Pr 3 + or U 4 + ion, we confirm that a residual entropy of 0.5 log 2 , a characteristic of two-channel Kondo phenomena, appears for the local Γ 3 non-Kramers doublet state. For further understanding on the Γ 3 state, the effective model is constructed on the basis of a j - j coupling scheme. Then, we rediscover the two-channel s - d model concerning quadrupole degrees of freedom. Finally, we briefly introduce our recent result on the two-channel Kondo effect for the case with three local f electrons. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
24. Implications of Lorentz symmetry violation on a 5D supersymmetric model.
- Author
-
García-Aguilar, J. D. and Pérez-Lorenzana, A.
- Subjects
- *
LORENTZ force , *SUPERSYMMETRY , *WESS-Zumino-Witten model , *PHASE transitions , *COMPACTIFICATION (Physics) - Abstract
Field models with extra spatial dimensions have a larger Lorentz symmetry which is broken down to the standard four-dimensional one by the compactification process. By considering Lorentz violating operators in a 5D supersymmetric Wess-Zumino model, which otherwise conserve the standard four-dimensional Poincaré invariance, we show that supersymmetry (SUSY) can be restored upon a simple deformation of the supersymmetric transformations. However, SUSY is not preserved in the effective 4D theory that arises after compactification when the 5D Lorentz violating operators do not preserve bulk parity. Our mechanism unveils a possible connection among Lorentz violation and the Scherk-Schwarz mechanism. We also show that parity preserving models, on the other hand, do provide well defined supersymmetric KK models. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
25. Chiral Symmetry and Effective Models for QCD
- Author
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Scholten, O., Kittel, W., editor, Mulders, P. J., editor, and Scholten, O., editor
- Published
- 2000
- Full Text
- View/download PDF
26. Resonance states in an effective chiral hadronic model
- Author
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Rau Philip, Steinheimer Jan, Schramm Stefan, and Stöcker Horst
- Subjects
effective model ,hadronic resonances ,qcd phase diagram ,susceptibilities ,Physics ,QC1-999 - Published
- 2012
- Full Text
- View/download PDF
27. Revisiting effective acoustic propagation in labyrinthine metasurfaces.
- Author
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Hagström, Joar Zhou, Pham, Kim, and Maurel, Agnès
- Subjects
- *
ASYMPTOTIC homogenization , *REFRACTIVE index , *RESONANCE , *ANISOTROPY - Abstract
We revisit the modelling of labyrinthine metasurfaces with space coiling design. To do so, we use homogenization theory which allows us to replace the actual structure by a slab filled with an effective, homogeneous and anisotropic, medium. The effective medium is highly anisotropic as the propagation is allowed in one direction only and its effective refractive index is obtained unambiguously thanks to the resolution of a static cell-problem. The result is compared to a classical, two-step, model which follows the intuitive idea that a coiled labyrinth and a slot being its uncoiled version behave the same. Beyond the approximation of such statement (the evanescent fields triggered at the turning regions of the labyrinth are neglected), we stress the difficulty in defining unambiguously the length of the uncoiled labyrinth. • Asymptotic homogenization theory for labyrinthine metasurfaces. • Effective medium with high anisotropy. • Fabry-pérot resonance for thin metasurfaces. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
28. Multiscale Modeling of Solidification
- Author
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Stefanescu, Doru Michael and Stefanescu, Doru Michael
- Published
- 2015
- Full Text
- View/download PDF
29. Correlation-induced valley topology in buckled graphene superlattices
- Author
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Rigotti Manesco, A.L. (author), Lado, Jose L. (author), Rigotti Manesco, A.L. (author), and Lado, Jose L. (author)
- Abstract
Quasi-flat-bands emerging in buckled monolayer graphene superlattices have been recently shown to realize correlated states analogous to those observed in twisted graphene multilayers. Here, we demonstrate the emergence of valley topology driven by competing electronic correlations in buckled graphene superlattices. We show, both by means of atomistic models and a low-energy description, that the existence of long-range electronic correlations leads to a competition between antiferromagnetic and charge density wave instabilities, that can be controlled by means of screening engineering. Interestingly, we find that the emergent charge density wave has a topologically non-trivial electronic structure, leading to a coexistent quantum valley Hall insulating state. In a similar fashion, the antiferromagnetic phase realizes a spin-polarized quantum valley-Hall insulating state. Our results put forward buckled graphene superlattices as a new platform to realize interaction-induced topological matter., Accepted Author Manuscript, QN/Akhmerov Group
- Published
- 2021
- Full Text
- View/download PDF
30. Confinement and dynamical chiral symmetry breaking in a non-perturbative renormalizable quark model.
- Author
-
Dudal, D., Guimaraes, M.S., Palhares, L.F., and Sorella, S.P.
- Subjects
- *
CHIRALITY of nuclear particles , *RENORMALIZATION (Physics) , *QUARK models , *MESONS , *DECAY constants , *QUANTUM chromodynamics - Abstract
Inspired by the construction of the Gribov–Zwanziger action in the Landau gauge, we introduce a quark model exhibiting both confinement and chiral symmetry aspects. An important feature is the incorporation of spontaneous chiral symmetry breaking in a renormalizable fashion. The quark propagator in the condensed vacuum turns out to be of a confining type. Besides a real pole, it exhibits complex conjugate poles. The resulting spectral form is explicitly shown to violate positivity, indicative of its unphysical character. Moreover, the ensuing quark mass function fits well to existing lattice data. To further validate the physical nature of the model, we identify a massless pseudoscalar (i.e. a pion) in the chiral limit and present estimates for the ρ meson mass and decay constant. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
31. Correlation-induced valley topology in buckled graphene superlattices
- Author
-
Jose L. Lado and A. L. R. Manesco
- Subjects
superlattices ,Superlattice ,FOS: Physical sciences ,grapheme ,02 engineering and technology ,Electronic structure ,Topology ,01 natural sciences ,quantum valley Hall effect ,law.invention ,Kane Mele model ,law ,Phase (matter) ,0103 physical sciences ,Mesoscale and Nanoscale Physics (cond-mat.mes-hall) ,Antiferromagnetism ,General Materials Science ,010306 general physics ,Quantum ,Topology (chemistry) ,Physics ,Condensed Matter - Mesoscale and Nanoscale Physics ,effective model ,Graphene ,Mechanical Engineering ,General Chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Condensed Matter::Mesoscopic Systems and Quantum Hall Effect ,Mechanics of Materials ,electronic correlations ,0210 nano-technology ,Charge density wave - Abstract
Flat bands emerging in buckled monolayer graphene superlattices have been recently shown to realize correlated states analogous to those observed in twisted graphene multilayers. Here, we demonstrate the emergence of valley topology driven by competing electronic correlations in buckled graphene superlattices. We show, both by means of atomistic models and a low-energy description, that the existence of long-range electronic correlations leads to a competition between antiferromagnetic and charge density wave instabilities, that can be controlled by means of screening engineering. Interestingly, we find that the emergent charge density wave has a topologically non-trivial electronic structure, leading to a coexistent quantum valley Hall insulating state. In a similar fashion, the antiferromagnetic phase realizes a spin-polarized quantum valley-Hall insulating state. Our results put forward buckled graphene superlattices as a new platform to realize interaction-induced topological matter., 7 pages, 6 figures
- Published
- 2021
32. AN INVESTIGATION OF THE COUPLING CONSTANTS IN QUANTUM HADRODYNAMICS EFFECTIVE MODELS.
- Author
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BURIGO, L. N., BODMANN, B. E. J., JACOBSEN, R. B., VASCONCELLOS, C. A. Z., and FERNÁNDEZ, F.
- Subjects
NUCLEAR matter ,RELATIVISTIC astrophysics ,QUANTUM electrodynamics ,NEUTRON stars ,HYPERONS ,MESONS - Published
- 2010
33. Leveraged BMIS Model for Cloud Risk Control.
- Author
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YouJin Song and Yasheng Pang
- Subjects
CLOUD computing ,BUSINESS models ,INFORMATION technology security ,FINANCIAL leverage ,INFORMATION resources management ,MATHEMATICAL optimization - Abstract
Cloud computing has increasingly been drawing attention these days. Each big company in IT hurries to get a chunk of meat that promises to be a whopping market in the future. At the same time, information is always associated with security and risk problems. Nowadays, the handling of these risks is no longer just a technology problem, with a good deal of literature focusing on risk or security management and framework in the information system. In this paper, we find the specific business meaning of the BMIS model and try to apply and leverage this model to cloud risk. Through a previous study, we select and determine the causal risk factors in cloud service, which are also known as CSFs (Critical Success Factors) in information management. Subsequently, we distribute all selected CSFs Into the BMIS model by mapping with ten principles in cloud risk. Finally, by using the leverage points, we try to leverage the model factors and aim to make a resource-optimized, dynamic, general risk control business model for cloud service providers. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
34. RESOURCE CLASSROOM AS A MODEL FOR ORGANIZING INCLUSIVE EDUCATION IN THE RUSSIAN FEDERATION
- Author
-
Nikolay Senchenkov and Olga Bliznyuk
- Subjects
Resource (project management) ,Social skills ,Work (electrical) ,Process (engineering) ,children with disabilities and special educational needs ,effective model ,inclusive education ,mainstream schools ,resource classroom ,special educational conditions ,space organization ,Generalization (learning) ,Mathematics education ,ComputingMilieux_COMPUTERSANDEDUCATION ,Mainstream ,Sociology ,Space (commercial competition) ,Inclusion (education) - Abstract
On the basis of inclusive education importance for children with disabilities and special educational needs, which contributes to the development of communication and socialization skills, as well as the development of tolerance among typically developing children, the aim of this work was to describe a resource classroom as a model for the effective organization of inclusive education in mainstream schools of the Russian Federation. The article defines a resource classroom in Russian educational system. The authors determine legal and regulatory frameworks to establish such classrooms. This study presents the main methodological base of resource classrooms, the organization for the educational process and space according to the students needs. Based on the generalization for the experience of the resource classrooms in the regions of the Russian Federation, the interaction for all elements of this model is shown. The study confirms that positive learning outcomes, involvement and inclusion of children with disabilities and special educational needs in a mainstream school and society are the evidence for the effectiveness of resource classrooms. The described model makes inclusion in education comfortable and effective not only for students of the resource classroom, but also for typically developing children, parents and the teaching staff of a school.
- Published
- 2020
35. RESOURCE CLASSROOM AS A MODEL FOR ORGANIZING INCLUSIVE EDUCATION IN THE RUSSIAN FEDERATION
- Author
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Bliznyuk, Olga, Senchenkov, Nikolay, Bliznyuk, Olga, and Senchenkov, Nikolay
- Abstract
On the basis of inclusive education importance for children with disabilities and special educational needs, which contributes to the development of communication and socialization skills, as well as the development of tolerance among typically developing children, the aim of this work was to describe a resource classroom as a model for the effective organization of inclusive education in mainstream schools of the Russian Federation. The article defines a resource classroom in Russian educational system. The authors determine legal and regulatory frameworks to establish such classrooms. This study presents the main methodological base of resource classrooms, the organization for the educational process and space according to the students needs. Based on the generalization for the experience of the resource classrooms in the regions of the Russian Federation, the interaction for all elements of this model is shown. The study confirms that positive learning outcomes, involvement and inclusion of children with disabilities and special educational needs in a mainstream school and society are the evidence for the effectiveness of resource classrooms. The described model makes inclusion in education comfortable and effective not only for students of the resource classroom, but also for typically developing children, parents and the teaching staff of a school.
- Published
- 2020
36. Suppression of superconductivity by inhomogeneous chiral condensation in the NJL2 model.
- Author
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Ebert, D., Khunjua, T. G., Klimenko, K. G., and Ch. Zhukovsky, V.
- Subjects
- *
SUPERCONDUCTIVITY , *INHOMOGENEOUS materials , *CHIRALITY of nuclear particles , *NUCLEAR models , *MATHEMATICAL symmetry , *GENERALIZATION , *QUARKS , *CHEMICAL potential - Abstract
We investigate the possibility of spatially inhomogeneous chiral and Cooper, or superconducting, pairing in the (1+1)-dimensional model by Chodos et al. [ Phys. Rev. D 61, 045011 (2000)] generalized to continuous chiral invariance. The consideration is performed at nonzero values of temperature T and quark number chemical potential μ. In the framework of the Fulde-Ferrel inhomogeneity ansatz for chiral and Cooper condensates, we show that if G1>G2, where G1 and G2 are the coupling constants in the quark-antiquark and diquark channels, then in the (μ, T)-phase diagram the superconducting phase is suppressed by spatially inhomogeneous chiral spiral phase with broken chiral symmetry. In contrast, in the above mentioned original Chodos et al. model, where only the opportunity for homogeneous condensates is taken into account, the superconducting phase is realized at sufficiently high values of μ at arbitrary values of G2>0, including the interval 0
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- 2014
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37. Effective models for nearly ideal Dirac semimetals
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Tang, Feng and Wan, Xiangang
- Published
- 2019
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38. Resonance states in an effective chiral hadronic model.
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Rau, Philip, Steinheimer, Jan, Schramm, Stefan, and Stöcker, Horst
- Abstract
With an effective chiral flavour SU(3) model we show the effect of hadronic resonances on the QCD phase diagram. We state that varying the resonance couplings to the scalar and vector fields affects the order and location of the phase transition, the possible existence of a critical end point (CEP), and the thermodynamic properties. We present (strange) quark number susceptibilities at zero baryochemical potential and at three different points at the phase transition. Comparing results to lattice QCD, we state that reasonable large vector couplings limit the phase transition to a smooth crossover ruling out a CEP. [ABSTRACT FROM AUTHOR]
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- 2012
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39. NUCLEAR MATTER SUPERFLUIDITY IN AN EFFECTIVE HADRONIC FIELD MODEL WITH EXCLUDED VOLUME CORRECTIONS.
- Author
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AGUIRRE, R. M.
- Subjects
- *
SUPERFLUIDITY , *NUCLEAR matter , *HADRONS , *FIELD theory (Physics) , *SYMMETRY (Physics) , *PARTICLES (Nuclear physics) , *TEMPERATURE effect , *MATHEMATICAL models - Abstract
Properties of the 1S0 superfluid phase are studied for symmetric nuclear matter at finite temperature. It is described within a covariant hadronic field model, of the σ-ω type, with addition of density dependent correlations simulating effects due to finite extension of nucleons. The model is solved in a self-consistent Hartree-Bogoliubov approach, assuming instantaneous interactions in the superfluid phase. A comparison with the results obtained from several hadronic field models is made. Main characteristics of our description of the superfluid gap are in qualitative agreement with some studies using microscopic potentials, although further refinements could improve its performance. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
40. THE ROLE OF ANTIKAON CONDENSATES IN THE EQUATION OF STATE OF NEUTRON STARS.
- Author
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FERNÁNDEZ, F., MESQUITA, A., RAZEIRA, M., and VASCONCELLOS, C. A. Z.
- Subjects
- *
NEUTRON stars , *PULSARS , *CATHODE rays , *GALAXY clusters , *PARTICLES (Nuclear physics) - Abstract
We study the consequences of the presence of a negative electric charge condensate of antikaons in neutron stars using an effective model with derivative couplings. In our formalism, nucleons interact through the exchange of σ, ω and ϱ mesons, in the presence of electrons and muons, to accomplish electric charge neutrality and beta equilibrium. The phase transition to the antikaon condensate was implemented through the Gibbs conditions combined with the mean-field approximation, giving rise to a mixed phase of coexistence between nucleon matter and the antikaon condensate. Assuming neutrino-free matter, we observe a rapid decrease of the electron chemical potential produced by the gradual substitution of electrons by kaons to accomplish electric charge neutrality. The exotic composition of matter in neutron star including antikaon condensation and nucleons can yield a maximum mass of about Mns ~ 1.76 M⊙. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
41. Homogenization of the Prager model in one-dimensional plasticity.
- Author
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Schweizer, Ben
- Subjects
- *
MATERIAL plasticity , *HYSTERESIS , *STOCHASTIC analysis , *ASYMPTOTIC homogenization , *PARTIAL differential equations - Abstract
We propose a new method for the homogenization of hysteresis models of plasticity. For the one-dimensional wave equation with an elasto-plastic stress-strain relation we derive averaged equations and perform the homogenization limit for stochastic material parameters. This generalizes results of the seminal paper by Franců and Krejčí. Our approach rests on energy methods for partial differential equations and provides short proofs without recurrence to hysteresis operator theory. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
42. On stabilized models in micromagnetics.
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Carstensen, Carsten and Praetorius, Dirk
- Subjects
- *
MAGNETS , *MAXWELL equations , *INTEGRAL operators , *INTEGRALS - Abstract
The effective behaviour of stationary micromagnetic phenomena is modelled by a convexified Landau–Lifshitz minimization problem for the limit of large and soft magnets Ω with no exchange energy. The numerical simulation of the resulting minimization problem has to overcome difficulties caused by the pointwise side-constraint $$|\bf{m}|\leq 1$$ and the stray-field energy on the unbounded domain $$\mathbb{R}^{d}$$ . A penalty method models the side-constraint and the exterior Maxwell equation is recast via a nonlocal integral operator $$\mathcal{L}$$ . This paper gives an overview of the available results and implementational details. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
- View/download PDF
43. An Effective Instructional System Design and Measurement of Quality and Practice of Web-Based Distance Learning.
- Author
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Rodchua, Suhansa
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INSTRUCTIONAL systems ,DISTANCE education ,ONLINE education ,INTERNET in education ,EDUCATORS - Abstract
On-line educators and institutes are still trying to figure out how best to use web-based technology as a way of delivering courses and how web-based tools and learning activities, such as discussion boards, e-mail, group projects, virtual chats, and interaction with classmates and instructor, influence students' learning. The study proposed an effective model for designing instructional materials and measuring quality of web-based courses in the Industrial Management Master online program. The research data were gathered from 137 students in eleven online courses between 2003-2006. An online questionnaire was utilized in measuring students' satisfaction of instructor's performance, instructional material design, technology and activities used, and supported services. Key components that on-line course developers and educators can use in their pedagogical process of Internet-based environments to promote student satisfaction and learning effectiveness are instructional and design strategies, instructor's performance, use of web-based technology and activities, student participation, and supported services. [ABSTRACT FROM AUTHOR]
- Published
- 2007
44. THE NUCLEAR MATTER COMPRESSIBILITY FUNCTION IN A PARAMETERIZED COUPLING MODEL.
- Author
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DEXHEIMER, VERÔNICA A., VASCONCELLOS, CÉSAR A. Z., and BODMANN, BARDO E. J.
- Subjects
- *
NUCLEAR matter , *HADRONS , *BARYONS , *MESONS , *MEAN field theory , *PARTICLES (Nuclear physics) - Abstract
In the framework of an effective derivative-coupling model with scalar and vector mesons coupled to the octet of baryons and leptonic degrees of freedom, we have calculated in detail the nuclear property known as the compressibility function, using the mean-field theory formalism and taking into account chemical equilibrium, baryon number and electric charge conservation. The parameters of the model are chosen in order to reproduce phenomenology: an effective nucleon mass between 0.7–0.8 MN and a compression modulus between 200–300 MeV. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
- View/download PDF
45. Effective simulation of a macroscopic model for stationary micromagnetics
- Author
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Carstensen, Carsten and Praetorius, Dirk
- Subjects
- *
MAGNETS , *MAXWELL equations , *INTEGRAL operators , *PARTIAL differential equations - Abstract
Abstract: The effective behaviour of stationary micromagnetic phenomena is modelled by a convexified Landau–Lifshitz minimization problem for the limit of large and soft magnets Ω without the exchange energy. The numerical simulation of the resulting minimization problem has to overcome difficulties caused by the pointwise side-restriction ∣m∣⩽1 and the stray field energy on the unbounded domain . A penalty method models the side-restriction and the exterior Maxwell equation is recast via a nonlocal integral operator . As shown in [Numer. Anal. Macrosc. Model Micromagnet, submitted for publication; Analysis, Numerik und Simulation eines Relaxierten Modellproblems zum Mikromagnetismus, doctoral thesis, Vienna University of Technology, 2003], the discretization leads to a nonlocal problem with piecewise constant ansatz and test functions and (dense) stiffness matrices with closed form formula for their entries. This paper addresses the numerical solution with Newton–Raphson schemes and the scientific computation of effective micromagnetic simulations. [Copyright &y& Elsevier]
- Published
- 2005
- Full Text
- View/download PDF
46. Eliminando o problema de duplicamento de férmions em nanofitas de grafeno: modelos e condições de contorno via teoria de grupos
- Author
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Ramon Guilherme Flávio Dornelas, Ferreira Junior, Gerson, Guerra, José de Los Santos, and Diniz, Ginetom Souza
- Subjects
Boudary Conditions ,Problemas de valores de contorno ,Effective Model ,Grafeno ,Física ,Condições de contorno ,Graphene ,Modelo efetivo ,CIENCIAS EXATAS E DA TERRA [CNPQ] - Abstract
CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Em 2004, K. Novoselov e A. Geim (Laureados com o Nobel de 2010) conseguiram isolar e depositar em um substrato uma única monocamada de carbono em uma estrutura hexagonal. Estes desenvolvimentos deram origem às pesquisas em materiais bidimensionais, e materiais que apresentam cones de Dirac na estrutura de bandas. O confinamento lateral da monocamada introduz as nanofitas de grafeno do tipo zigzag e armchair, cujos nomes se referem a aparência do arranjo dos átomos de carbono em suas bordas. Nesta dissertação, investigamos teoricamente a estrutura eletrônica e condições de contorno destas nanofitas sob novas perspectivas. O modelo efetivo do grafeno é dado por um Hamiltoniano (tipo Dirac) linear no momento k, o que introduz duas peculiaridades. Primeiro, o confinamento eletrônico não é obtido pela condição de contorno trivial de caixa fechada (ψ = 0 nas fronteiras). Em seu lugar, costuma-se usar as condições de contorno de Brey e Fertig (BF), nas quais as estruturas atomísticas das bordas devem ser levadas em consideração. Segundo, quando simulações numéricas são necessárias, o processo de discretização do operador k = −i∂x via diferenças finitas leva ao problema do duplicamento de Férmions em Hamiltonianos k-lineares, que introduz soluções numéricas espúrias próximas ao nível de Fermi. Adicionalmente, as condições de contorno de Brey e Fertig não são implementáveis na abordagem por diferenças finitas. Assim, nesta dissertação revemos estes problemas, a priori distintos, e descobrimos que estão intimamente relacionados e propomos uma solução única. Nossos resultados são fundamentados na demonstração de que as condições de contorno de BF são equivalentes às de McCann e Fal’ko (MF), sendo que estas últimas são válidas para qualquer Hamiltoniano k-linear. Veremos que as condições de MF podem ser estabelecidas por teoria de grupos e são definidas pelas quebras de simetria impostas pelo confinamento. Também utilizando teoria de grupos, mostramos que as correções k-quadráticas do Hamiltoniano das nanofitas são dadas por formas matriciais equivalentes às que definem as condições de MF. Demonstramos aqui que estas correções quadráticas, conhecidas como massa de Wilson, além de resolver o problema do duplicamento de Férmions, modificam as condições de contorno para a forma trivial de ψ = 0 nas fronteiras. Esta nossa proposta de uma nova abordagem para estudos de Hamiltonianos dominados K-lineares ainda não é estabelecida na literatura. No entanto é de grande abrangência, pois nossos resultados são válidos não só para grafeno, mas para todos os Hamiltonianos k-lineares em estado sólido, como em isolantes topológicos, férmions de Weyl, etc. In 2004, N. Novoselov and A. Geim (Nobel 2010) have isolated a single layer of graphene on a substrate. Thus yielding novel research fields in two-dimensional materials, and materials that are characterized by Dirac cones in their electronic structure. The lateral confinement of a monolayer introduces the graphene nanoribbons, which can be of the type zigzag or armchair, whose names refer to the shape of the atomic arrangement at their borders. In this dissertation, we investigate the electronic structure and boundary conditions of graphene nanoribbons under novel perspectives. The effective model of graphene is given by a Dirac Hamiltonian, linear in momentum k, which introduces subtleties. First, the hard wall confinement is not given by trivial boundary conditions (ψ = 0 at the Edges). Instead, one usually applies the Brey and Fertig (BF) boundary conditions, which requires an analysis of the atomistic terminations of each boundary. Second, whenever numerical simulations are necessary, the discretization of the operator k = −i∂x, via the finite differences method, yield the Fermion doubling problem for k-linear Hamiltonians, which introduces spurious numerical solutions near the Fermi energy. Moreover, the BF conditions are not compatible with the finite differences method. Here, in this dissertation, we revisit these issues, which are seemingly unrelated, to find out that they are closely related, allowing us to propose an unique solution. Our results are based on the demonstration that the BF boundary conditions are equiv- alent to those introduced by McCann and Fal’ko (MF), which are valid for all k-linear Hamiltonians. We will show that the MF conditions can be established using group theory, being defined by the broken symmetries caused by the confinement. The group theory analysis also allow us to show that the k-quadratic corrections of the Hamiltonian are given by the same matrices that define the MF conditions. We show here that these quadratic corrections, known as Wilson’s mass, not only solves the Fermion doubling problem, but also modify the boundary conditions, allowing for the trivial ψ = 0 condition at the edges. Our proposal for a new approach for Hamiltonians dominated by k-linear terms is not yet established in the literature. However, it is of broad interest, since our results are valid beyond graphene, and can be applied to all k-linear models, like topological insulators, Weyl fermions, etc. Dissertação (Mestrado)
- Published
- 2020
- Full Text
- View/download PDF
47. Encyclopedia of emergent particles in three-dimensional crystals.
- Author
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Yu ZM, Zhang Z, Liu GB, Wu W, Li XP, Zhang RW, Yang SA, and Yao Y
- Abstract
The past decade has witnessed a surge of interest in exploring emergent particles in condensed matter systems. Novel particles, emerged as excitations around exotic band degeneracy points, continue to be reported in real materials and artificially engineered systems, but so far, we do not have a complete picture on all possible types of particles that can be achieved. Here, via systematic symmetry analysis and modeling, we accomplish a complete list of all possible particles in time-reversal-invariant systems. This includes both spinful particles such as electron quasiparticles in solids, and spinless particles such as phonons or even excitations in electric-circuit and mechanical networks. We establish detailed correspondence between the particle, the symmetry condition, the effective model, and the topological character. This obtained encyclopedia concludes the search for novel emergent particles and provides concrete guidance to achieve them in physical systems., (Copyright © 2021 Science China Press. Published by Elsevier B.V. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
48. Tailoring drug release rates in hydrogel-based therapeutic delivery applications using graphene oxide
- Author
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Puvirajesinghe, Tania M, Lane, Zhi, Craster, Richard, Guenneau, Sebastien, Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Aix Marseille Université (AMU), King‘s College London, Department of Mathematics [Imperial College London], Imperial College London, Abraham de Moivre (UMI2004), Imperial College London-Centre National de la Recherche Scientifique (CNRS), EPSILON (EPSILON), Institut FRESNEL (FRESNEL), Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Aix Marseille Université (AMU), Official collaboration between Institut Paoli Calmettes (T.M. Puvirajesinghe), Institut Fresnel (S. Guenneau), Imperial College London (R.V. Craster) and Kings College London (Z. L. Zhi), Engineering & Physical Science Research Council (EPSRC), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Abraham de Moivre, and Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics] ,biocompatibility ,[SDV.BIO]Life Sciences [q-bio]/Biotechnology ,effective model ,General Science & Technology ,MD Multidisciplinary ,mass diffusion ,graphene oxide ,[SDV.CAN]Life Sciences [q-bio]/Cancer ,[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology ,drug delivery media - Abstract
This work is the experimental proof of concept for the biochemical cloaks first proposed in the same journal by Guenneau and Puvirajesinghe (J. R. Soc. Interface 10, 20130106, 2013). A European patent has been filed by the four authors of the paper with INSERM transfert on this topic.; International audience; Graphene oxide (GO) is increasingly used for controlling mass diffusion in hydrogel-based drug delivery applications. On the macro-scale, the density of GO in the hydrogel is a critical parameter for modulating drug release. Here, we investigate the diffusion of a peptide drug through a network of GO membranes and GO-embedded hydrogels, modelled as porous matrices resembling both laminated and ‘house of cards’ structures. Our experiments use a therapeutic peptide and show a tunable nonlinear dependence of the peptide concentration upon time. We establish models using numerical simulations with a diffusion equation accounting for the photo-thermal degradation of fluorophores and an effective percolation model to simulate the experimental data. The modelling yields an interpretation of the control of drug diffusion through GO membranes, which is extended to the diffusion of the peptide in GO-embedded agarose hydrogels. Varying the density of micron-sized GO flakes allows for fine control of the drug diffusion. We further show that both GO density and size influence the drug release rate. The ability to tune the density of hydrogel-like GO membranes to control drug release rates has exciting implications to offer guidelines for tailoring drug release rates in hydrogel-based therapeutic delivery applications.
- Published
- 2018
- Full Text
- View/download PDF
49. Effective one-dimensional models including two-particle interaction from matrix product states
- Author
-
Keim, Frederik, Uhrig, Götz S., and Anders, Frithjof
- Subjects
Effective model ,Interaction ,Matrix product states ,Spin chains ,Spinsystem ,Spinkette - Abstract
In this thesis a method for deriving effective models for one-dimensional spin systems is introduced. It is based on matrix product state (MPS) and exploits translation invariance to efficiently work in the thermodynamic limit. It is tested on two analytically solvable models: The ferromagnetic spin-\textonehalf\ Heisenberg chain in an external field, and the transverse magnetic field Ising model (TFIM). The previously developed ansatz for one-particle states is extended to the description of two-particle states. The challenges of this extension and different choices for a basis of the two-particle space are discussed. Results for the two-particle spectral weight in the TFIM and for quasi-particle scattering in both models are provided.
- Published
- 2018
- Full Text
- View/download PDF
50. Tailoring drug release rates in hydrogel-based therapeutic delivery applications using graphene oxide
- Author
-
T M, Puvirajesinghe, Z L, Zhi, R V, Craster, and S, Guenneau
- Subjects
effective model ,mass diffusion ,Hydrogels ,Membranes, Artificial ,Life Sciences–Physics interface ,Drug Liberation ,Drug Delivery Systems ,biocompatibility ,Models, Chemical ,graphene oxide ,Graphite ,drug delivery media ,Research Article - Abstract
Graphene oxide (GO) is increasingly used for controlling mass diffusion in hydrogel-based drug delivery applications. On the macro-scale, the density of GO in the hydrogel is a critical parameter for modulating drug release. Here, we investigate the diffusion of a peptide drug through a network of GO membranes and GO-embedded hydrogels, modelled as porous matrices resembling both laminated and ‘house of cards’ structures. Our experiments use a therapeutic peptide and show a tunable nonlinear dependence of the peptide concentration upon time. We establish models using numerical simulations with a diffusion equation accounting for the photo-thermal degradation of fluorophores and an effective percolation model to simulate the experimental data. The modelling yields an interpretation of the control of drug diffusion through GO membranes, which is extended to the diffusion of the peptide in GO-embedded agarose hydrogels. Varying the density of micron-sized GO flakes allows for fine control of the drug diffusion. We further show that both GO density and size influence the drug release rate. The ability to tune the density of hydrogel-like GO membranes to control drug release rates has exciting implications to offer guidelines for tailoring drug release rates in hydrogel-based therapeutic delivery applications.
- Published
- 2017
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