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The purpose of this study was to determine the effect of giving Moringa oliefera L leaf meal through feed as an anti-bacterial to prevent infection with E.ictaluri bacteria in catfish (Pangasius hypopthalmus). This research was conducted from March 2020 to April 2020 at the Fish Health Laboratory, Freshwater Aquaculture Fisheries Center (BPBAT) Jambi. The research method used was a completely randomized design with five treatments and three replications. Catfish were fed for 14 days with treatment feed with each treatment (A. 5% / kg feed), (B. 10% / kg feed), (C. 15% / kg feed), (D. Commercial feed ) and (E. Commercial feed). and on the 16th day the fish were injected with the Edwarsiella ictaluri bacteria, and survival was observed from day 16 to day 26. The results showed that treatment of moringa leaf meal (C. 15% / kg of feed), could prevent bacterial infection E. ictaluri in catfish with the highest survival rate reaching 66.67%, fish growth of 5.78 grams / head, and feed conversion of 0.18% / kg of feed.

In February 2002, mass mortalities were first observed among striped catfish Pangasius hypophthalmus reared in freshwater ponds of central Sumatra, Indonesia. The affected fish showed pale gills, abdominal swelling and hemorrhage of the skin, as well as swelling of internal organs with white patches. Edwardsiella ictaluri was isolated from the internal organs of the diseased fish. The isolates showed pathogenicity to P. hypophthalmus by an artificial infection. However, the isolate preserved in a semisolid BHI agar for 6 months lost pathogenicity.

Three regions of koi herpesvirus (KHV) genomic DNA were compared for 34 samples from Japan, six from Indonesia, two from Taiwan, one from the Philippines, 13 from the Netherlands, one from the UK, one from the USA and one from Israel. The analyzed genomic regions included known PCR-detection targets (Sphl-5, 9/5 and the thymidine kinase gene). The KHVs from Asian countries were very homogeneous, although two variants were noted based on a single nucleotide polymorphism. In contrast, seven variants were found in KHVs from outside of Asia, and although closely related to one another, they were clearly distinct from those from Asian. The results suggest that a clear genetic distinction exists between Asian and European (including each single isolate from the USA and Israel) types of KHV, and that unique types of KHV were independently introduced or emerged in the respective geographic locations.