Search

Your search keyword '"Edwin Pitono"' showing total 2 results
Start Over Author "Edwin Pitono"
2 results on '"Edwin Pitono"'

1. The effects of chikungunya virus infection on people living with HIV during the 2014 Martinique outbreak.

Author

Mathilde Pircher, Edwin Pitono, Sandrine Pierre-François, Sabine Molcard, Lauren Brunier-Agot, Laurence Fagour, Fatiha Najioullah, Raymond Cesaire, Sylvie Abel, Lise Cuzin, and André Cabié

Subjects
Medicine, Science
Abstract

Our objective was to describe the clinical presentation of chikungunya virus (CHIKV) infection in patients living with HIV (PLHIV) during the 2014 Martinique outbreak. During the outbreak and the 6 following months, all PLHIV coming in our unit for a medical evaluation answered questions about potential CHIKV related symptoms, and had blood tests to assess the diagnosis. For patients coming in at the acute phase of infection, we are able to provide and analyze CD4+, CD8+ T-cells and HIV viral load evolution before, during and after CHIK infection. Among the 1 003 PLHIV in care in the center at the time of the outbreak, 188 (94 men and 94 women) had confirmed (following the WHO definition) CHIKV infection. Clinical presentation was common in 63% of the cases, severe and atypical forms were scarce. During the acute phase, CD4+ and CD8+ T-cells (evaluated in 30 PLHIV, 15 men and 15 women) absolute numbers dropped significantly, but returned to pre-CHIKV values after the acute phase. Reassuringly, CD4 and CD8 T cells proportions did not decrease during the acute phase. CHIKV infection had no significant impact on this anti-retroviral treated population.

Published
2020
Full Text
View/download PDF

2. The effects of chikungunya virus infection on people living with HIV during the 2014 Martinique outbreak

Author

Lise Cuzin, Sabine Molcard, Fatiha Najioullah, Laurence Fagour, Raymond Césaire, André Cabié, Mathilde Pircher, Sandrine Pierre-François, Lauren Brunier-Agot, Sylvie Abel, Edwin Pitono, Infectious Diseases and Tropical Medicine Unit [Fort-de-France, Martinique], CHU de la Martinique [Fort de France], Unit of Physical and Rehabilitation Medicine [Fort-de-France, Martinique], Department of Rheumatology [Fort-de-France, Martinique], Laboratoire de Virologie [Fort-de-France, Martinique], Maladies infectieuses et tropicales dans la Caraïbe (MAITC EA 4537), CHU Pointe-à-Pitre/Abymes [Guadeloupe] -CHU de la Martinique [Fort de France]-Université des Antilles (UA), Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Centre d'Investigation Clinique Antilles-Guyane (CIC - Antilles Guyane), Université des Antilles et de la Guyane (UAG)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pointe-à-Pitre/Abymes [Guadeloupe] -CHU de Fort de France-Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), and Bodescot, Myriam

Subjects
RNA viruses, Male, Viral Diseases, Pulmonology, Epidemiology, HIV Infections, medicine.disease_cause, Pathology and Laboratory Medicine, Geographical locations, Disease Outbreaks, White Blood Cells, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Animal Cells, Medicine and Health Sciences, Medicine, 030212 general & internal medicine, Chikungunya, Young adult, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, education.field_of_study, Multidisciplinary, Chikungunya Virus, T Cells, virus diseases, Middle Aged, 3. Good health, Infectious Diseases, Medical Microbiology, Viral Pathogens, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Viruses, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, HIV clinical manifestations, Female, Pathogens, Cellular Types, Martinique, Viral load, Research Article, Neglected Tropical Diseases, Adult, medicine.medical_specialty, Adolescent, Science, Alphaviruses, Immune Cells, 030231 tropical medicine, Population, Immunology, Cytotoxic T cells, Microbiology, Virus, Togaviruses, 03 medical and health sciences, Young Adult, Internal medicine, Humans, education, Microbial Pathogens, Caribbean, Blood Cells, Biology and life sciences, business.industry, Organisms, Outbreak, Chikungunya Infection, Cell Biology, Tropical Diseases, Diagnostic medicine, Respiratory Infections, North America, Chronic Disease, Chikungunya Fever, People and places, business
Abstract

International audience; Our objective was to describe the clinical presentation of chikungunya virus (CHIKV) infection in patients living with HIV (PLHIV) during the 2014 Martinique outbreak. During the outbreak and the 6 following months, all PLHIV coming in our unit for a medical evaluation answered questions about potential CHIKV related symptoms, and had blood tests to assess the diagnosis. For patients coming in at the acute phase of infection, we are able to provide and analyze CD4+, CD8+ T-cells and HIV viral load evolution before, during and after CHIK infection. Among the 1 003 PLHIV in care in the center at the time of the outbreak, 188 (94 men and 94 women) had confirmed (following the WHO definition) CHIKV infection. Clinical presentation was common in 63% of the cases, severe and atypical forms were scarce. During the acute phase, CD4+ and CD8+ T-cells (evaluated in 30 PLHIV, 15 men and 15 women) absolute numbers dropped significantly, but returned to pre-CHIKV values after the acute phase. Reassuringly, CD4 and CD8 T cells proportions did not decrease during the acute phase. CHIKV infection had no significant impact on this anti-retroviral treated population.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results