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Your search keyword '"Edwards-Brown, Mary"' showing total 29 results
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29 results on '"Edwards-Brown, Mary"'

1. Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial

Author

Robertson, Kent A, Nalepa, Grzegorz, Yang, Feng-Chun, Bowers, Daniel C, Ho, Chang Y, Hutchins, Gary D, Croop, James M, Vik, Terry A, Denne, Scott C, Parada, Luis F, Hingtgen, Cynthia M, Walsh, Laurence E, Yu, Menggang, Pradhan, Kamnesh R, Edwards-Brown, Mary K, Cohen, Mervyn D, Fletcher, James W, Travers, Jeffrey B, Staser, Karl W, Lee, Melissa W, Sherman, Marcie R, Davis, Cynthia J, Miller, Lucy C, Ingram, David A, and Clapp, D Wade

Published
2012
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5. Is it all in his head?

Author

Zimmer, Jennifer, Bhatt, Jay, Conway, James H., Edwards-Brown, Mary, and Sokol, Deborah K.

Subjects
Sinusitis -- Development and progression, Sinusitis -- Complications and side effects, Sinusitis -- Case studies, Blood clot -- Development and progression, Blood clot -- Drug therapy, Blood clot -- Causes of, Blood clot -- Case studies, Thrombosis -- Development and progression, Thrombosis -- Drug therapy, Thrombosis -- Causes of, Thrombosis -- Case studies, Thrombosis in children -- Development and progression, Thrombosis in children -- Drug therapy, Thrombosis in children -- Causes of, Thrombosis in children -- Case studies, Children -- Diseases, Children -- Development and progression, Children -- Drug therapy, Children -- Causes of, Children -- Case studies, Health
Abstract

Table of Contents Abstract Introduction Discussion References Abstract In this case report, of a teenage boy presents to your emergency room with headache and cranial nerve palsies. Differential diagnosis discussed [...]

Published
2006

6. Disappearing lesion in linear nevus sebaceous syndrome

Author

Zimmer, Jennifer, Edwards-Brown, Mary, and Sokol, Deborah K.

Subjects
Learning disabilities -- Risk factors, Learning disabilities -- Diagnosis, Learning disabilities -- Care and treatment, Learning disabilities -- Case studies, Neurofibromatosis -- Complications and side effects, Neurofibromatosis -- Case studies, Skin lesions -- Diagnosis, Skin lesions -- Care and treatment, Skin lesions -- Case studies, Health
Abstract

Table of Contents Abstract Introduction Case Report References Abstract Disappearing lesions, or unidentified bright objects (UBOs), have been demonstrated on MRI of patients with neurofibromatosis type I (NF1). Clinically UBOs [...]

Published
2006

7. Clinical correlates of white-matter abnormalities on head magnetic resonance imaging

Author

Dimassi, Hani, Lasbury, Nora, Garg, Bhuwan, Cowan, Linda D., Edwards-Brown, Mary, Bodensteiner, John B., Dimassi, Hani, Lasbury, Nora, Garg, Bhuwan, Cowan, Linda D., Edwards-Brown, Mary, and Bodensteiner, John B.

Abstract

We undertook this study to investigate the relationship between white-matter abnormalities (seen on brain magnetic resonance imaging [MRI]) and muscle tone and muscle stretch reflexes on clinical examination. We identified all patients less than 5 years of age who had undergone cranial MRI studies at Riley Hospital for Children between June 30, 1999, and July 1, 2000, whose scans were read as showing white-matter abnormalities. We measured two ratios and the thickness of the corpus callosum as indicators of the quantity of cerebral white matter. The ratios were R1, the ratio of the thickness of the white matter at the level just above the body of the lateral ventricle compared with the width of the hemisphere, and R2, the ratio of the thickness of the white matter to the width of the hemisphere at the level of the trigone of the lateral ventricle. The thickness of the corpus callosum was measured at the junction of the anterior two thirds and the posterior third. We also evaluated the signal intensity of the cerebral white matter by reviewing the fluid-attenuated inversion-recovery images and grading the signal as normal to severely abnormal depending on the degree and extent of high signal intensity seen (0 = normal to 4+). Thirty-eight children less than 5 years of age who underwent MRI scans between June and August 2000 and who were found to have normal tone prospectively and normal MRI scan on review served as a control group. We identified 215 patients who had white-matter abnormalities; of these, only 142 (66%) had documented tone assessments in their medical record. Our study group was divided into three groups: increased (n = 35), decreased (n = 53), and normal tone (n = 54). All three measurements of white matter in each of the three study groups were significantly below values for control children. The children with white-matter abnormalities and decreased tone had significantly less signal intensity abnormality than the other study groups. Children with w

Published
2015

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