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2. DESNT: A Poor Prognosis Category of Human Prostate Cancer

Author

Luca, Bogdan-Alexandru, Brewer, Daniel S., Edwards, Dylan R., Edwards, Sandra, Whitaker, Hayley C., Merson, Sue, Dennis, Nening, Cooper, Rosalin A., Hazell, Steven, Warren, Anne Y., Eeles, Rosalind, Lynch, Andy G., Ross-Adams, Helen, Lamb, Alastair D., Neal, David E., Sethia, Krishna, Mills, Robert D., Ball, Richard Y., Curley, Helen, Clark, Jeremy, Moulton, Vincent, and Cooper, Colin S.

Published
2018
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5. Visual Overview from Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow

Author

Grünwald, Barbara, primary, Vandooren, Jennifer, primary, Gerg, Michael, primary, Ahomaa, Kaarin, primary, Hunger, Annique, primary, Berchtold, Sonja, primary, Akbareian, Sophia, primary, Schaten, Susanne, primary, Knolle, Percy, primary, Edwards, Dylan R., primary, Opdenakker, Ghislain, primary, and Krüger, Achim, primary

Published
2023
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6. Supplementary Figure S2 from Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow

Author

Grünwald, Barbara, primary, Vandooren, Jennifer, primary, Gerg, Michael, primary, Ahomaa, Kaarin, primary, Hunger, Annique, primary, Berchtold, Sonja, primary, Akbareian, Sophia, primary, Schaten, Susanne, primary, Knolle, Percy, primary, Edwards, Dylan R., primary, Opdenakker, Ghislain, primary, and Krüger, Achim, primary

Published
2023
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7. Data from Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow

Author

Grünwald, Barbara, primary, Vandooren, Jennifer, primary, Gerg, Michael, primary, Ahomaa, Kaarin, primary, Hunger, Annique, primary, Berchtold, Sonja, primary, Akbareian, Sophia, primary, Schaten, Susanne, primary, Knolle, Percy, primary, Edwards, Dylan R., primary, Opdenakker, Ghislain, primary, and Krüger, Achim, primary

Published
2023
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8. Supplementary Figure Legends from Systemic Ablation of MMP-9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL6 Expression in the Bone Marrow

Author

Grünwald, Barbara, primary, Vandooren, Jennifer, primary, Gerg, Michael, primary, Ahomaa, Kaarin, primary, Hunger, Annique, primary, Berchtold, Sonja, primary, Akbareian, Sophia, primary, Schaten, Susanne, primary, Knolle, Percy, primary, Edwards, Dylan R., primary, Opdenakker, Ghislain, primary, and Krüger, Achim, primary

Published
2023
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9. Supplementary Figure 2 from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence

Author

Allen, Michael D., primary, Thomas, Gareth J., primary, Clark, Sarah, primary, Dawoud, Marwa M., primary, Vallath, Sabarinath, primary, Payne, Sarah J., primary, Gomm, Jennifer J., primary, Dreger, Sally A., primary, Dickinson, Sarah, primary, Edwards, Dylan R., primary, Pennington, Caroline J., primary, Sestak, Ivana, primary, Cuzick, Jack, primary, Marshall, John F., primary, Hart, Ian R., primary, and Jones, J. Louise, primary

Published
2023
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10. Supplementary Figure 3 from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence

Author

Allen, Michael D., primary, Thomas, Gareth J., primary, Clark, Sarah, primary, Dawoud, Marwa M., primary, Vallath, Sabarinath, primary, Payne, Sarah J., primary, Gomm, Jennifer J., primary, Dreger, Sally A., primary, Dickinson, Sarah, primary, Edwards, Dylan R., primary, Pennington, Caroline J., primary, Sestak, Ivana, primary, Cuzick, Jack, primary, Marshall, John F., primary, Hart, Ian R., primary, and Jones, J. Louise, primary

Published
2023
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11. Supplementary Table 1 from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence

Author

Allen, Michael D., primary, Thomas, Gareth J., primary, Clark, Sarah, primary, Dawoud, Marwa M., primary, Vallath, Sabarinath, primary, Payne, Sarah J., primary, Gomm, Jennifer J., primary, Dreger, Sally A., primary, Dickinson, Sarah, primary, Edwards, Dylan R., primary, Pennington, Caroline J., primary, Sestak, Ivana, primary, Cuzick, Jack, primary, Marshall, John F., primary, Hart, Ian R., primary, and Jones, J. Louise, primary

Published
2023
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12. Supplementary Figure 1 from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence

Author

Allen, Michael D., primary, Thomas, Gareth J., primary, Clark, Sarah, primary, Dawoud, Marwa M., primary, Vallath, Sabarinath, primary, Payne, Sarah J., primary, Gomm, Jennifer J., primary, Dreger, Sally A., primary, Dickinson, Sarah, primary, Edwards, Dylan R., primary, Pennington, Caroline J., primary, Sestak, Ivana, primary, Cuzick, Jack, primary, Marshall, John F., primary, Hart, Ian R., primary, and Jones, J. Louise, primary

Published
2023
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13. Supplementary Methods from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence

Author

Allen, Michael D., primary, Thomas, Gareth J., primary, Clark, Sarah, primary, Dawoud, Marwa M., primary, Vallath, Sabarinath, primary, Payne, Sarah J., primary, Gomm, Jennifer J., primary, Dreger, Sally A., primary, Dickinson, Sarah, primary, Edwards, Dylan R., primary, Pennington, Caroline J., primary, Sestak, Ivana, primary, Cuzick, Jack, primary, Marshall, John F., primary, Hart, Ian R., primary, and Jones, J. Louise, primary

Published
2023
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15. Supplementary Figure 4 from Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling

Author

Kopitz, Charlotte, primary, Gerg, Michael, primary, Bandapalli, Obul Reddy, primary, Ister, Dilek, primary, Pennington, Caroline J., primary, Hauser, Stephanie, primary, Flechsig, Christin, primary, Krell, Hans-Willi, primary, Antolovic, Dalibor, primary, Brew, Keith, primary, Nagase, Hideaki, primary, Stangl, Manfred, primary, Hann von Weyhern, Claus W., primary, Brücher, Björn L.D.M., primary, Brand, Karsten, primary, Coussens, Lisa M., primary, Edwards, Dylan R., primary, and Krüger, Achim, primary

Published
2023
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16. Supplementary Figure 3 from Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling

Author

Kopitz, Charlotte, primary, Gerg, Michael, primary, Bandapalli, Obul Reddy, primary, Ister, Dilek, primary, Pennington, Caroline J., primary, Hauser, Stephanie, primary, Flechsig, Christin, primary, Krell, Hans-Willi, primary, Antolovic, Dalibor, primary, Brew, Keith, primary, Nagase, Hideaki, primary, Stangl, Manfred, primary, Hann von Weyhern, Claus W., primary, Brücher, Björn L.D.M., primary, Brand, Karsten, primary, Coussens, Lisa M., primary, Edwards, Dylan R., primary, and Krüger, Achim, primary

Published
2023
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17. Supplementary Figure 5 from Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling

Author

Kopitz, Charlotte, primary, Gerg, Michael, primary, Bandapalli, Obul Reddy, primary, Ister, Dilek, primary, Pennington, Caroline J., primary, Hauser, Stephanie, primary, Flechsig, Christin, primary, Krell, Hans-Willi, primary, Antolovic, Dalibor, primary, Brew, Keith, primary, Nagase, Hideaki, primary, Stangl, Manfred, primary, Hann von Weyhern, Claus W., primary, Brücher, Björn L.D.M., primary, Brand, Karsten, primary, Coussens, Lisa M., primary, Edwards, Dylan R., primary, and Krüger, Achim, primary

Published
2023
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20. Supplementary Figure 1 from Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling

Author

Kopitz, Charlotte, primary, Gerg, Michael, primary, Bandapalli, Obul Reddy, primary, Ister, Dilek, primary, Pennington, Caroline J., primary, Hauser, Stephanie, primary, Flechsig, Christin, primary, Krell, Hans-Willi, primary, Antolovic, Dalibor, primary, Brew, Keith, primary, Nagase, Hideaki, primary, Stangl, Manfred, primary, Hann von Weyhern, Claus W., primary, Brücher, Björn L.D.M., primary, Brand, Karsten, primary, Coussens, Lisa M., primary, Edwards, Dylan R., primary, and Krüger, Achim, primary

Published
2023
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21. Data from Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion

Author

Gutiérrez-Fernández, Ana, primary, Fueyo, Antonio, primary, Folgueras, Alicia R., primary, Garabaya, Cecilia, primary, Pennington, Caroline J., primary, Pilgrim, Simon, primary, Edwards, Dylan R., primary, Holliday, Deborah L., primary, Jones, J. Louise, primary, Span, Paul N., primary, Sweep, Fred C.G.J., primary, Puente, Xose S., primary, and López-Otín, Carlos, primary

Published
2023
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23. Supplementary Figure 2 from Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling

Author

Kopitz, Charlotte, primary, Gerg, Michael, primary, Bandapalli, Obul Reddy, primary, Ister, Dilek, primary, Pennington, Caroline J., primary, Hauser, Stephanie, primary, Flechsig, Christin, primary, Krell, Hans-Willi, primary, Antolovic, Dalibor, primary, Brew, Keith, primary, Nagase, Hideaki, primary, Stangl, Manfred, primary, Hann von Weyhern, Claus W., primary, Brücher, Björn L.D.M., primary, Brand, Karsten, primary, Coussens, Lisa M., primary, Edwards, Dylan R., primary, and Krüger, Achim, primary

Published
2023
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24. Supplementary Figure 1 from Matrix Metalloproteinase-8 Functions as a Metastasis Suppressor through Modulation of Tumor Cell Adhesion and Invasion

Author

Gutiérrez-Fernández, Ana, primary, Fueyo, Antonio, primary, Folgueras, Alicia R., primary, Garabaya, Cecilia, primary, Pennington, Caroline J., primary, Pilgrim, Simon, primary, Edwards, Dylan R., primary, Holliday, Deborah L., primary, Jones, J. Louise, primary, Span, Paul N., primary, Sweep, Fred C.G.J., primary, Puente, Xose S., primary, and López-Otín, Carlos, primary

Published
2023
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29. Novel Degradome Markers in Breast Cancer

Author

Pennington, Caroline J., Pilgrim, Simon, Span, Paul N., Sweep, Fred C., Edwards, Dylan R., Edwards, Dylan, editor, Høyer-Hansen, Gunilla, editor, Blasi, Francesco, editor, and Sloane, Bonnie F., editor

Published
2008
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34. Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15

Author

Kelwick, Richard, Wagstaff, Laura, Decock, Julie, Roghi, Christian, Cooley, Lindsay S., Robinson, Stephen D., Arnold, Hugh, Gavrilović, Jelena, Jaworski, Diane M., Yamamoto, Kazuhiro, Nagase, Hideaki, Seubert, Bastian, Krüger, Achim, and Edwards, Dylan R.

Published
2015
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36. Conformation-Specific Inhibitory Anti-MMP-7 Monoclonal Antibody Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Chemotherapeutic Cell Kill

Author

Mohan, Vishnu, primary, Gaffney, Jean P., additional, Solomonov, Inna, additional, Levin, Maxim, additional, Klepfish, Mordehay, additional, Akbareian, Sophia, additional, Grünwald, Barbara, additional, Dym, Orly, additional, Eisenstein, Miriam, additional, Yu, Kenneth H., additional, Kelsen, David P., additional, Krüger, Achim, additional, Edwards, Dylan R., additional, and Sagi, Irit, additional

Published
2021
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38. MMP-1 drives immunopathology in human tuberculosis and transgenic mice

Author

Elkington, Paul, Shiomi, Takayuki, Breen, Ronan, Nuttall, Robert K., Ugarte-Gil, Cesar Augusto, Walker, Naomi F., Saraiva, Luisa, Pedersen, Bernadette, Mauri, Francesco, Lipman, Marc, Edwards, Dylan R., Robertson, Brian D., D'Armiento, Jeanine, and Friedland, Jon S.

Subjects
Proteases -- Physiological aspects -- Research, Tuberculosis -- Development and progression -- Research, HIV patients -- Health aspects, Health care industry
Abstract

Mycobacterium tuberculosis can cause lung tissue damage to spread, but the mechanisms driving this immunopathology are poorly understood. The breakdown of lung matrix involves MMPs, which have a unique ability [...]

Published
2011
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43. Performance and health economic evaluation of the Mount Sinai COVID-19 serological assay identifies modification of thresholding as necessary to maximise specificity of the assay

Author

Rushworth, Stuart A, primary, Johnson, Benjamin B, additional, Ashurst, Karen, additional, Davidson, Rose, additional, Paddy, Paige, additional, Mistry, Jayna J, additional, Moore, Jamie A, additional, Hellmich, Charlotte, additional, Edwards, Dylan R, additional, Da Luz Afonso, Daniela, additional, Xydopoulos, Georgios, additional, Goodwin, Richard, additional, Gomez, Javier, additional, Prakash, Reenesh, additional, Dervisevic, Samir, additional, Fordham, Richard, additional, Bowles, Kristian M, additional, and Smith, James G W, additional

Published
2020
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46. Matrix metalloproteinases and diseases of the CNS

Author

Yong, Voon Wee, Krekoski, Craig A., Forsyth, Peter A., Bell, Robert, and Edwards, Dylan R.

Subjects
Metalloenzymes -- Physiological aspects, Central nervous system diseases -- Physiological aspects, Health, Psychology and mental health
Abstract

Matrix metalloproteinases (MMPs) are increasingly being implicated in the pathogenesis of several CNS diseases. In multiple sclerosis, MMPs could be responsible for the influx of inflammatory mononuclear cells into the CNS, contribute to myelin destruction and disrupt the integrity of the blood-brain barrier; in Alzheimer's disease, MMPs might mediate the deposition of amyloid [Beta]-proteins; and MMPs are known to contribute to the invasiveness of malignant glioma cells and might regulate their angiogenic capacity. Nonetheless, MMPs could also have beneficial roles in recovery from CNS injury. Therefore, both the identity of the MMP and its cellular origin could determine whether disease pathogenesis or regeneration occurs, and thus synthetic MMP inhibitors might be valuable for treating some CNS diseases.

Published
1998

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