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1. Duration of morning hyperinsulinemia determines hepatic glucose uptake and glycogen storage later in the day.

2. Morning Engagement of Hepatic Insulin Receptors Improves Afternoon Hepatic Glucose Disposal and Storage.

3. Duration of Morning Hyperinsulinemia Determines Hepatic Glucose Uptake and Glycogen Storage Later in the Day.

4. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog.

5. A high-fat and fructose diet in dogs mirrors insulin resistance and β-cell dysfunction characteristic of impaired glucose tolerance in humans.

6. Integration of metabolic flux with hepatic glucagon signaling and gene expression profiles in the conscious dog.

7. A physiologic increase in brain glucagon action alters the hepatic gluconeogenic/glycogenolytic ratio but not glucagon's overall effect on glucose production.

8. Profound Sensitivity of the Liver to the Direct Effect of Insulin Allows Peripheral Insulin Delivery to Normalize Hepatic but Not Muscle Glucose Uptake in the Healthy Dog.

9. The Importance of the Mechanisms by Which Insulin Regulates Meal-Associated Liver Glucose Uptake in the Dog.

10. Importance of the route of insulin delivery to its control of glucose metabolism.

11. Liver glycogen-induced enhancements in hypoglycemic counterregulation require neuroglucopenia.

12. Safety of surgical denervation of the common hepatic artery in insulin-resistant dogs.

13. The kinetics of glucagon action on the liver during insulin-induced hypoglycemia.

14. Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes.

15. Effect of portal glucose sensing on incretin hormone secretion in a canine model.

16. Sympathetic Denervation of the Common Hepatic Artery Lessens Glucose Intolerance in the Fat- and Fructose-Fed Dog.

17. Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.

18. Glucose autoregulation is the dominant component of the hormone-independent counterregulatory response to hypoglycemia in the conscious dog.

19. Insulin's direct hepatic effect explains the inhibition of glucose production caused by insulin secretion.

20. Hepatic glycogen can regulate hypoglycemic counterregulation via a liver-brain axis.

21. Hepatic and Whole-Body Insulin Metabolism during Proestrus and Estrus in Mongrel Dogs.

22. Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes.

23. Effects of Habitat Complexity on Pair-Housed Zebrafish.

24. Is brain insulin action relevant to the control of plasma glucose in humans?

25. Changes in glucose and fat metabolism in response to the administration of a hepato-preferential insulin analog.

26. Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice.

27. Effects of intraportal exenatide on hepatic glucose metabolism in the conscious dog.

29. Effects of 11β-hydroxysteroid dehydrogenase-1 inhibition on hepatic glycogenolysis and gluconeogenesis.

30. Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog.

31. Evidence against a physiologic role for acute changes in CNS insulin action in the rapid regulation of hepatic glucose production.

32. Physiologic action of glucagon on liver glucose metabolism.

33. Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs.

35. Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo.

36. Effect of 11 beta-hydroxysteroid dehydrogenase-1 inhibition on hepatic glucose metabolism in the conscious dog.

37. Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo.

38. The role of CCK8 in the inhibition of glucose production.

39. Inhaled insulin is associated with prolonged enhancement of glucose disposal in muscle and liver in the canine.

40. Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog.

41. Current strategies for the inhibition of hepatic glucose production in type 2 diabetes.

42. Intraportally delivered GLP-1, in the presence of hyperglycemia induced via peripheral glucose infusion, does not change whole body glucose utilization.

43. Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog.

44. Insulin action on the liver in vivo.

45. Intraportal GLP-1 infusion increases nonhepatic glucose utilization without changing pancreatic hormone levels.

46. Triglyceride uptake and lipoprotein lipase-generated fatty acid spillover in the splanchnic bed of dogs.

47. A novel glucagon receptor antagonist, NNC 25-0926, blunts hepatic glucose production in the conscious dog.

48. Inhalation of human insulin is associated with improved insulin action compared with subcutaneous injection and endogenous secretion in dogs.

49. Inhalation of human insulin (exubera) augments the efficiency of muscle glucose uptake in vivo.

50. Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial hepatic specific 11beta hydroxysteroid dehydrogenase type 1 activity.

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