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6. Endovascular Treatment of Acute Ischemic Stroke With the Penumbra System in Routine Practice: COMPLETE Registry Results

Author

Zaidat, Osama O., primary, Fifi, Johanna T., additional, Nanda, Ashish, additional, Atchie, Benjamin, additional, Woodward, Keith, additional, Doerfler, Arnd, additional, Tomasello, Alejandro, additional, Tekle, Wondwossen, additional, Singh, Inder Paul, additional, Matouk, Charles, additional, Thalwitzer, Jörg, additional, Jargiełło, Tomasz, additional, Skrypnik, Dmitry, additional, Beuing, Oliver, additional, Berge, Jérôme, additional, Katz, Jeffrey M., additional, Biondi, Alessandra, additional, Bonovich, David, additional, Sheth, Sunil A., additional, Yoo, Albert J., additional, Hassan, Ameer E., additional, Piotin, Michel, additional, Blanc, Raphaël, additional, Desilles, Jean-Philippe, additional, Ciccio, Gabriele, additional, Smajda, Stanislas, additional, Marnat, Gaultier, additional, Barreau, Xavier, additional, Ménégon, Patrice, additional, Gariel, Florent, additional, Dörfler, Arnd, additional, Engelhorn, Tobias, additional, Gölitz, Philipp, additional, Schmidt, Manuel, additional, Lang, Stefan, additional, Mühlen, Iris, additional, Rösch, Julie, additional, Knott, Michael, additional, Lücking, Hannes, additional, Hoelter, Philip, additional, Schramm, Peter, additional, Neumann, Alexander, additional, Eckey, Thomas, additional, Boppel, Tobias, additional, Krah, Mike, additional, Schwarze, Jens, additional, Manikowski, Bettina, additional, Ladig, Philipp, additional, Albert, Nathanael, additional, Otto, Carmen, additional, Lemme, Anne, additional, Brandt, Silvio, additional, Bohner, Georg, additional, Kleine, Justus, additional, Siebert, Eberhard, additional, Bauknecht, Hans-Christian, additional, Wiener, Edzard, additional, Donitza, Aneta, additional, Górnik, Michał, additional, Pyra, Krzysztof, additional, Roman, Tomasz, additional, Szajner, Maciej, additional, Ficek, Remigiusz, additional, Prus, Katarzyna, additional, Stachowicz, Sylwia, additional, Wojczal, Joanna, additional, Sojka, Michał, additional, Buraczyńska, Kinga, additional, Luchowski, Piotr, additional, Anisimov, Kirill, additional, Sukhanova, Ekaterina, additional, Shloydo, Eugene, additional, Kravchenko, Kirill, additional, Golikov, Konstantin, additional, Sergeev, Aleksey, additional, Udovichenko, Anna, additional, Georgiev, Roman, additional, Gasparyan, Eduard, additional, Malov, Svyatoslav, additional, Ploschenkov, Eugeny, additional, Tomasello Weitz, Alejandro, additional, Ribó, Marc, additional, Hernández, David, additional, Rodriguez-Luna, David, additional, García-Tornel, Álvaro, additional, Rubiera, Marta, additional, Juega, Jesús, additional, Muchada, Marian, additional, Villatoro, Noelia Rodríguez, additional, Boned Riera, Sandra, additional, Pagola, Jorge, additional, Deck Román, Matías, additional, Piñana Plaza, Carlos, additional, Zamarro Parra, Joaquín, additional, Parrilla, Guillermo, additional, Espinosa de Rueda Ruiz, Mariano, additional, García-Villalba Navaridas, Blanca, additional, Díaz Pérez, José, additional, Hellinger, Frank, additional, Gandhi, Ravi, additional, Bellew, Michael, additional, Bellon, Richard, additional, Frei, Do, additional, Kaminsky, Ian, additional, Arias, Eric, additional, Katz, Jeffrey, additional, Woo, Henry, additional, Molina, Ina Teron, additional, Patel, Anand, additional, Libman, Richard, additional, Arora, Rohan, additional, Hixson, Harry, additional, Graham, Cole, additional, Moftakhar, Roham, additional, Diaz, Orlando, additional, Klucznik, Richard, additional, Alexander, Michael, additional, Jackson, Robert, additional, Padrick, Matthew, additional, Dumitrascu, Oana, additional, Schlick, Konrad, additional, Olivas, Edgar, additional, Song, Shlee, additional, Barnard, Zachary, additional, Madarang, Ernest John, additional, Reeves, Alan, additional, Paul Singh, Inder, additional, Fifi, Johanna, additional, Shoriah, Hazem, additional, Yaeger, Kurt, additional, Majidi, Shahram, additional, DeLacey, Reade, additional, Keller, Christopher, additional, Shigematsu, Tomoyoshi, additional, Yaniv, Gal, additional, Oxley, Thomas, additional, Georgiadis, Alexandros, additional, Hassan, Ameer, additional, Herber, Ryan, additional, Bahrassa, Farhad, additional, Johnson, Michele, additional, Hawk, Harris, additional, Quarfordt, Steven, additional, Nichols, Michael, additional, Calvert, Justin, additional, Starke, Robert, additional, Yavagal, Dileep, additional, Peterson, Eric, additional, Altschul, Dorothea, additional, Sattar, Ahsan, additional, Ali Aziz-Sultan, Mohammed, additional, Large, Daniel, additional, Patel, Nirav, additional, Chen, Karen, additional, Ziayee, Habibullah, additional, Du, Rose, additional, Frerichs, Kai, additional, Patel, Akshal, additional, Monteith, Stephen, additional, Loh, Yince, additional, Aref, Mohammed, additional, Tjoumakaris, Stavropoula, additional, Herial, Nabeel, additional, Jabbour, Pacal, additional, Rosenwasser, Robert, additional, Reid Gooch, Michael, additional, Zarzour, Hekmat, additional, Taqi, Muhammad, additional, Hoit, Daniel, additional, Arthur, Adam, additional, Elijovich, Lucas, additional, Nickele, Christopher, additional, Inoa, Violiza, additional, Goyal, Nitin, additional, Torabi, Radmehr, additional, Dornbos, David, additional, Peterson, Jeremy, additional, Maidan, Lucian, additional, Luh, George, additional, Kale, Sushant, additional, Alshekhlee, Amer, additional, Farid, Hamed, additional, Bress, Aaron, additional, Senturk, Cagin, additional, Milburn, Jim, additional, Vidal, Gabriel, additional, Gulotta, Paul, additional, Valle-Giler, Edison, additional, Turkel-Parrella, David, additional, Gordon, David S., additional, Liff, Jeremy, additional, Arcot, Karthik, additional, Farkas, Jeffrey, additional, Adamczyk, Peter, additional, Zaidat, Osama, additional, Lin, Eugene, additional, Ezzeldin, Mohammad, additional, Sultan-Qurraie, Ali, additional, Alenzi, Badar, additional, Teleb, Mohamed, additional, Abuawad, Mazen, additional, Viktoria Totoraitis, Ruta, additional, and Richard, Paul, additional

Published
2022
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8. Loko-regionär dominante Erdheim Chester Disease (ECD)

Author

Özden, Filiz, Schinke, Susanne, Thorns, Christoph, Eckey, Thomas, Dalhoff, Klaus, Humrich, Jens, Riemekasten, Gabriela, and Lamprecht, Peter

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Vier Patienten mit unterschiedlich organzentrierten Symptomen kamen zur stationären Aufnahme: Bei Patientin 1 bestanden neurologische Symptome, bei Patientin 2 eine rezidivierende globale kardiale Dekompensation und bei Patient 3 und Patientin 4 rezidivierende Schwellungen im Orbita-[zum vollständigen Text gelangen Sie über die oben angegebene URL], 45. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 31. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 27. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2017

11. 64-jährige Patientin mit sukzessiver rechtseitiger homonymer Hemianopsie, Stauungspapille, Amaurosis und hohem ANA-Titer

Author

Schinke, Susanne, Niehus, Stine-Grete, Thorns, Christoph, Eckey, Thomas, Münte, Thomas, Riemekasten, Gabriela, and Lamprecht, Peter

Subjects
ddc: 610, Erdheim Chester Erkrankung, 610 Medical sciences, Medicine, Histiozyten, CD1a, CD68, S100
Abstract

Vorgeschichte: Bei der 64-jährigen Patientin wurde 1979 eine Colitis ulcerosa diagnostiziert. Nach einem Rezidiv der Colitis wurde sie seit 2011 mit 75mg 6-Mercaptopurin und 2g Mesalazin täglich behandelt. Jährliche Kontrollkoloskopien zeigten seither eine Remission der Colitis ulcerosa[zum vollständigen Text gelangen Sie über die oben angegebene URL], 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2016

15. MR Thermometry Analysis of Sonication Accuracy and Safety Margin of Volumetric MR Imaging–guided High-Intensity Focused Ultrasound Ablation of Symptomatic Uterine Fibroids

Author

Kim, Young-sun, primary, Trillaud, Hervé, additional, Rhim, Hyunchul, additional, Lim, Hyo K., additional, Mali, Willem, additional, Voogt, Marianne, additional, Barkhausen, Jörg, additional, Eckey, Thomas, additional, Köhler, Max O., additional, Keserci, Bilgin, additional, Mougenot, Charles, additional, Sokka, Shunmugavelu D., additional, Soini, Jouko, additional, and Nieminen, Heikki J., additional

Published
2012
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19. Detection of anti-neutrophil cytoplasmic and antinuclear autoantibodies favouring misdiagnoses in 5 cases of Erdheim-Chester disease.

Author

Özden F, Schinke S, Thorns C, Eckey T, Dalhoff K, Münte TF, Tronnier V, Humrich JY, Riemekasten G, and Lamprecht P

Subjects
Aged, Erdheim-Chester Disease diagnosis, Erdheim-Chester Disease genetics, Humans, Middle Aged, Mutation, Proto-Oncogene Proteins B-raf genetics, Antibodies, Antineutrophil Cytoplasmic immunology, Antibodies, Antinuclear immunology, Diagnostic Errors, Erdheim-Chester Disease immunology
Published
2018

20. 111In-labeled CD34+ hematopoietic progenitor cells in a rat myocardial infarction model.

Author

Brenner W, Aicher A, Eckey T, Massoudi S, Zuhayra M, Koehl U, Heeschen C, Kampen WU, Zeiher AM, Dimmeler S, and Henze E

Subjects
Animals, Disease Models, Animal, Feasibility Studies, Female, Hematopoietic Stem Cells pathology, Humans, Isotope Labeling, Myocardial Infarction metabolism, Myocardial Infarction pathology, Radionuclide Imaging, Rats, Rats, Nude, Treatment Outcome, Antigens, CD34 metabolism, Hematopoietic Stem Cell Transplantation methods, Hematopoietic Stem Cells diagnostic imaging, Hematopoietic Stem Cells metabolism, Myocardial Infarction diagnostic imaging, Myocardial Infarction surgery, Organometallic Compounds, Oxyquinoline analogs & derivatives, Radiopharmaceuticals
Abstract

Unlabelled: Transplantation of progenitor cells (PCs) has been shown to improve neovascularization and left ventricular function after myocardial ischemia. The fate of transplanted PCs has been monitored by fluorescence labeling or by genetic modifications introducing reporter genes. However, these techniques are limited by the need to kill the experimental animal. The aim of this study was to radiolabel CD34(+) hematopoietic PCs (HPCs) with (111)In-oxine and to evaluate the feasibility of this in vivo method for monitoring myocardial homing of transplanted cells in a rat myocardial infarction model., Methods: Human HPCs were isolated from mobilized peripheral blood and labeled with (111)In-oxine. Labeled HPCs were injected into the cavity of the left ventricle in nude rats 24 h after induction of myocardial infarction (n = 4) or sham operation (n = 4). Scintigraphic images were acquired up to 96 h after HPC injection. After animals were killed, tissue samples of various organs were harvested to calculate tissue-specific activity and for immunostaining., Results: Labeling efficiency of HPCs was 32% +/- 11%. According to trypan-blue staining, viability of radiolabeled HPCs was impaired by 30% after 48 and 96 h in comparison with unlabeled cells, whereas proliferation and differentiation of HPCs was nullified after 7 d, as assessed by colony-forming assays. After injection of HPCs, the specific activity ratio of heart to peripheral muscle tissue increased from 1.10 +/- 0.32 in sham-operated rats to 2.47 +/- 0.92 (P = 0.020) in infarcted rats. However, the overall radioactivity detected in the heart was only about 1%. A transient high lung uptake of 17% +/- 6% was observed within the first hour after infusion of HPCs. At 24 h after injection, the initial lung activity had shifted toward liver, kidneys, and spleen, resulting in an increase of radioactivity in these organs from 37% +/- 6% to 57% +/- 5%., Conclusion: Radiolabeling with (111)In-oxine is a feasible in vivo method for monitoring transplanted HPCs in a rat myocardial infarction model. The potential to detect differences in myocardial homing between infarcted and normal hearts suggests that this method may provide a noninvasive imaging approach for clinical trials using transplanted HPCs in patients. Our findings, however, also demonstrated a negative effect of (111)In-oxine on cellular function, which resulted in complete impairment of HPC proliferation and differentiation. For future trials in stem cell imaging with (111)In-oxine, therefore, it will be mandatory to carefully check for radiation-induced cell damage.

Published
2004

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