71,856 results on '"East Asia"'
Search Results
2. Two new species of the genus Agramma (Hemiptera, Heteroptera, Tingidae) from small islands of Japan, with an illustrated key to the Japanese species of the genus
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Souma, Jun and Pensoft Publishers
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East Asia ,host plant ,molecular data ,new species ,phytophagous insect ,taxonomy - Published
- 2024
3. Examining Pareto Law across department store shoppers.
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Tanusondjaja, Arry, Romaniuk, Jenni, Nenycz-Thiel, Magda, Sakashita, Mototaka, and Viswanathan, Vijay
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CUSTOMER retention ,CONSUMERS ,CUSTOMER loyalty programs ,DEPARTMENT stores ,CHAIN stores ,CUSTOMER loyalty ,REVENUE accounting - Abstract
Department stores invest in loyalty strategies that largely focus on retaining current high value customers in response to increasing competition in retail shopping. In this study, we examine the contribution of the top 20% customers for transaction frequency and value ("heavy buyers") to the total sales, and the consistency of this contribution across departments within a store. We also investigate the heavy buyer stability over time across 3 years, from over 550 million transactions from a department store chain in East Asia. The results show that the Pareto ratio of the top 20% spenders account for 71% of revenue (and 52% of the total transactions), and the top 20% transactors represent 58% of revenue (and 62% of total transactions), which may signal the role of such heavy buyers to overall stores sales. At each department level, the heavy buyers (by value) contribute from 65% to 86% of the department revenue. Despite this, the stability of the top 20% segment over time varies greatly by department from 11% to 74%. Finally, whether high value customers in one department store also translate across departments, depends mainly on the department size in terms of its shopper penetration. The research furthers our knowledge on Pareto Law, with important implications for customer retention strategies and loyalty programs especially for retailers. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Ageing risks in four Asian Tigers: global health crisis and implications for productive welfare regimes
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Tian, Zhen, Yuda, Tauchid Komara, and Hu, Zhiming
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- 2024
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5. Living the dream: Nanai shamanic experiments and porous engagements in the Siberian far east
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Stelmaszyk, Mally and Sungorkin, Leonid
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- 2024
6. Neurodiversity paradigms and their development across cultures: Some reflections in East Asian contexts.
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Hirota, Tomoya, Cheon, Keun-Ah, and Lai, Meng-Chuan
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SERIAL publications , *TERMS & phrases , *NEURODIVERSITY , *CULTURE , *AUTISM , *REFLECTION (Philosophy) , *LINGUISTICS , *MEDICAL research , *ASPERGER'S syndrome , *CULTURAL pluralism - Abstract
The authors share examples of local contexts that could contribute to the shaping of neurodiversity paradigms and movements in East Asia, complementing examples in other non-Western regions. Cited are the complexity of the linguistic nuances of the translated terms about autism in the historical and social-cultural contexts, the contribution of linguistic differences to the shaping of autism identities, and the difference of autism advocacy efforts by linguistic and social-cultural contexts.
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- 2024
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7. Late transition to parenthood in high-income and low-fertility East Asian societies.
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Chen, Mengni
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LIFE course approach , *PARENTHOOD , *FERTILITY ,WESTERN countries - Abstract
Late transition to parenthood is no longer a phenomenon only observed in Europe; rather, it is even more prominent in high-income and low-fertility East Asian societies. Yet, there is a significant gap in the literature about the trends, causes and consequences of late child bearing in Asian societies. Underpinning the ultra-low fertility rates in high-income East Asian societies including Hong Kong, South Korea, Taiwan, Singapore, and Japan is the significant delay in transitioning to parenthood. The median age at first birth in these societies is now the oldest among all high-income societies globally, and more than 20 per cent of all first births occurred to women aged 35 and above. Taking a life course perspective to investigate the shifting age norm for parenthood and the causes of late parenthood would provide a more insightful understanding of the phenomenon. In addition, the consequences of late parenthood observed in Western countries are also likely to manifest in these societies, with intergenerational consequences deserving special attention within the Asian context. [ABSTRACT FROM AUTHOR]
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- 2024
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8. Vertical profile measurements for ammonia in a Japanese deciduous forest using denuder sampling technique: ammonia emissions near the forest floor.
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Xu, Mao, Matsumoto, Ryota, Chanonmuang, Phuvasa, and Matsuda, Kazuhide
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Ammonia (NH
3 ) has received considerable attention as a major reduced nitrogen. However, accurate estimates of the deposition amount are difficult due to its complex behavior characterized by bidirectional exchange between the atmosphere and the surface. We observed the vertical profile of NH3 concentration in a deciduous forest in Japan for 1 year to further advance the studies on NH3 bidirectional exchange in Asia, especially focusing on the process near the forest floor. The observation period lasted from September 29, 2020, to September 28, 2021, including leafy and leafless periods. Using the denuder sampling technique, we measured NH3 concentration in the forest at three heights (above the forest canopy, 30 m, and near the forest floor, 2 m and 0.2 m). NH3 concentrations tended to be highest at the top of the canopy (30 m). Focusing on the concentration near the forest floor, the concentrations at 0.2 m were frequently higher than those at 2 m regardless of the leafy and leafless period, thus suggesting NH3 emissions from the forest floor. NH3 concentration near the forest floor showed strong positive correlations with air temperature during the leafy period. The NH3 emissions from the forest floor during the leafy period were possibly due to the decomposition of leaf litter with increased air temperature. The decrease in leaf area index might induced the increase in NH3 concentration and emission. NH3 emission during the leafless period was also possibly dependent on the state of the deposition surface, apart from air temperature, relative humidity, and leaf area index. [ABSTRACT FROM AUTHOR]- Published
- 2024
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9. The Evolution of Educating for Sustainable Development in East Asia: A Bibliometric Review, 1991–2023.
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Hallinger, Philip, Jayaseelan, Sujitra, and Speece, Mark W.
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This systematic review addressed the need for documentation and analysis of the scope and topical foci of research on education for sustainable development (ESD) in East Asia. The review used descriptive, content, and keyword co-occurrence analyses to synthesize features of 1915 Scopus-indexed journal articles published between 1991 and 2023. The authors found that research interest in ESD in East Asia has grown rapidly, accelerated by the pronouncement of the United Nations Decade of Education for Sustainable Development in 2005 and the Sustainability Agenda 2030 in 2015. Researchers in China, Malaysia, Japan, South Korea, Indonesia, and Thailand have been the leading contributors to this regional knowledge base. Consistent with global ESD reviews, content analysis revealed that this literature emerged from studies of environmental education and gradually expanded to include sociocultural, economic, and integrated perspectives on sustainability. Keyword co-occurrence analysis revealed three thematic clusters: Environmental Sustainability in Education, Social Sustainability in Education, and Teaching and Learning for Sustainability. Temporal co-word analysis highlighted the research front, which includes environmental research focusing on carbon/energy issues, technology-enhanced learning for sustainability, empirical research methods for studying ESD, and, to a lesser degree, studies of the economic pillar of sustainability in education. Recommendations are offered for future research. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Morality through the lens of Confucian heritage countries: collective self variations and moral worldviews.
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Takamatsu, Reina, Joonha Park, and Akiko Matsuo
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CONFUCIAN ethics ,DUTY ,REDUCTIONISM ,PSYCHOLOGY ,ETHICS - Abstract
The issue of Western, Educated, Industrialized, Rich, and Democratic (WEIRD) samples dominating research has been ongoing for decades, and now the emerging trend is to turn to theoretical perspectives from the Majority World. Adopting Western-centric methods based on reductionism can overlook important details and differences between similar cultures, particularly in East Asian cultures, where the Confucian values of relational harmony take many forms. We discuss a novel theoretical perspective on moral constitutions in Confucian heritage cultures. Our central tenet is that divergent moral concepts and ideals are present in Confucian cultures because each culture emphasizes a specific pillar and the self is situated differently in the social relationships that define the scope of interpersonal moral obligations. We consider three Confucian countries: China, Japan, and South Korea as examples. Despite geographical proximity and conventional categorization in cultural psychology, each Confucian country manifests distinct patterns of the self, moral ideals, and behavior in socio-moral contexts. To understand how and why moral worldviews vary within a region, we need to examine how the self in socio-cultural contexts differs and guides interpersonal norms and behaviors across sociocultural contexts. We conclude this paper by offering methodological recommendations for including indigenous moral concepts outside the WEIRD context. [ABSTRACT FROM AUTHOR]
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- 2024
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11. The impact of regional trade agreements on trade efficiency in East Asia: a stochastic frontier gravity approach.
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Zhu, Haoliang
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COMMERCIAL treaties ,IMPORTS - Abstract
This paper aims to investigate how selected regional trade agreements (RTAs) affect trade efficiency in East Asia, which is measured by the ratio of actual exports to their maximum potential export value. To achieve this, we use a stochastic frontier gravity model and bilateral trade data of 16 countries from 1990 to 2018. Our results indicate that RTAs generally improve trade efficiency between member countries. Moreover, we distinguish between intra-bloc and extra-bloc trade, and found that export diversion due to RTAs is rare in East Asia. On the other hand, our result shows that the imports of ASEAN countries tend to divert away from non-members. [ABSTRACT FROM AUTHOR]
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- 2024
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12. Tropical cyclone landfalls in the Northwest Pacific under global warming.
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Kim, So‐Hee and Ahn, Joong‐Bae
- Abstract
This study projects the changes in tropical cyclone (TC) landfalls in the western North Pacific under shared socioeconomic pathway (SSPs) scenarios during the TC peak season by using low‐resolution global climate models participating in the Coupled Model Intercomparison Project phase 6 (CMIP6). Projections are based on the relationship between mid‐ and lower‐level atmospheric circulation and TC landfall frequency during the historical period from 1985 to 2014 and the future climate period from 2015 to 2100. The landfall areas for TCs are divided into northern East Asia (NEA), middle East Asia (MEA) and southern East Asia (SEA); the TC peak seasons are July–September for NEA and MEA, and July–November for SEA. To evaluate reproducibility, both ensemble and individual model outputs for mid‐ and lower‐level atmospheric circulations associated with TC landfall in each East Asian subregion are compared to the reanalysis. An ensemble of seven models with stable results for all three regions is more reasonable in simulating atmospheric circulation patterns than an ensemble of all CMIP6 models. The findings suggest that TC landfall is projected to increase by about 12% and 32% in NEA and MEA, respectively, in the late 21st century under the SSP5‐8.5 scenario compared to the historical period, while decreasing by 13% in SEA. These changes are consistent under both warming scenarios, and are more pronounced in the SSP5‐8.5 scenario compared to SSP1‐2.6, particularly in the later period of this century. An analysis of future atmospheric circulations suggests that global warming will weaken the western North Pacific subtropical high and cause its boundary to retreat eastward. This will lead to changes in the steering flow, which is closely related to TC tracks, resulting in TC landfalls to increase or decrease depending on the East Asian subregion. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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13. East Asia's private higher education crisis: Demography as destiny?
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Welch, Anthony
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HIGHER education , *DEMOGRAPHY , *COVID-19 pandemic , *FINANCE - Abstract
Globally, one in three students are now enrolled in private higher education institutions (PHEIs), with the total reaching almost 70 million enrolments. This pattern is similar across a highly diverse Asia: more than 35% of students are enrolled in the private sector, and around 60% of higher education institutions (usually much smaller than their public counterparts) are private. But in East Asia, a combination of high participation rates and a rapidly ageing demographic has led to a complex, developing crisis, particularly in a much‐expanded private sector. Adding to the existing suite of problems – finance, over‐supply, declining standards, regulatory issues, and in some cases, corruption – the combined effect of recent COVID disruptions, regional economic reversals, and a rapidly ageing demographic has intensified existing problems, constituting a major crisis for the sector, especially more marginal private institutions. The analysis charts the various responses of governments in Japan, South Korea, Taiwan, and China, draws out some of the limits to reform, and poses the dilemma for the future of private higher education in the region. [ABSTRACT FROM AUTHOR]
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- 2024
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14. Age of Rocks and Peculiarities of the Formation of the Dariganga Volcanic Field, Southeastern Mongolia.
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Yarmolyuk, V. V., Kozlovsky, A. M., Savatenkov, V. M., and Kudryashova, E. A.
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GEOLOGICAL time scales , *VOLCANIC fields , *VOLCANIC ash, tuff, etc. , *VOLCANIC eruptions , *CENOZOIC Era - Abstract
The results of systematic geochronological (K–Ar) studies of rocks of the Dariganga volcanic field (DVF) composed of Late Cenozoic mafic lavas are presented. Four stages of its evolution are distinguished: the Middle–Late Miocene (>10 Ma), Late Miocene–Early Pliocene (7.8–3.5 Ma), Late Pliocene (2.8–2.6 Ma), and Pleistocene (<1.7 Ma). The products of these stages are regularly distributed within the volcanic field. The main volume of eruptions was related to the Late Miocene–Early Pliocene and Pleistocene stages. The northwestern part of the lava field as a lava plateau formed during the Late Miocene–Early Pliocene. The eruptions are related to a local structural depression, which originated under extension accompanying volcanism. The southeastern part of the DVF formed during the Pleistocene volcanic eruption. Volcanism accompanied the formation of the Khukhot-Ein-Nuru Ridge in the Nukut-Daban Uplift and was responsible for the morphological peculiarities of the volcanic cover. A typical feature of it includes the large multicentered shield volcanoes related to the axial zone of the ridge, as well as the elongated valley flows along both slopes. The peculiarities of the formation of the DVF and other volcanic areas of the Late Cenozoic intraplate volcanic province of Central and East Asia are compared. Their consistent evolution indicates that the formation of the DVF was controlled by the same geodynamic mechanisms as the formation of other volcanic areas of the province, namely, by the activity of a small mantle plume. [ABSTRACT FROM AUTHOR]
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- 2024
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15. High‐resolution atmospheric CO2 concentration data simulated in WRF‐Chem over East Asia for 10 years.
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Seo, Min‐Gyung, Kim, Hyun Mee, and Kim, Dae‐Hui
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ATMOSPHERIC carbon dioxide , *METEOROLOGICAL research , *MOLE fraction , *WEATHER forecasting , *CARBON dioxide , *CARBON cycle - Abstract
In this study, high‐resolution CO2 concentration data were generated for East Asia to analyse long‐term changes in atmospheric CO2 concentrations, as East Asia is an important region for understanding the global carbon cycle. Using the Weather Research and Forecasting model coupled with Chemistry (WRF‐Chem), atmospheric CO2 concentrations were simulated in East Asia at a resolution of 9 km for a period of 10 years (2009–2018). The generated CO2 concentration data include CO2 concentrations, biogenic CO2 concentrations, anthropogenic CO2 concentrations, oceanic CO2 concentrations, biospheric CO2 uptake, biospheric CO2 release and meteorological variables at 3‐h intervals. The simulated high‐resolution CO2 concentrations, biogenic CO2 concentrations and anthropogenic CO2 concentrations are stored in NetCDF‐4 (Network Common Data Form, version 4) format and are available for download at https://doi.org/10.7910/DVN/PJTBF3. The simulated annual mean surface CO2 concentrations in East Asia were 391.027 ppm in 2009 and 412.949 ppm in 2018, indicating an increase of 21.922 ppm over the 10‐year period with appropriate seasonal variabilities. The monthly mean CO2 concentrations in East Asia were verified using surface CO2 observations and satellite column‐averaged CO2 mole fraction (XCO2) from Orbiting Carbon Observatory 2 (OCO‐2). Based on surface CO2 observations and OCO‐2 XCO2 concentrations, the average root‐mean‐square error (RMSE) of the simulated CO2 concentrations in WRF‐Chem was 2.474 and 0.374 ppm, respectively, which is smaller than the average RMSE of the low‐resolution CarbonTracker 2019B (CT2019B) simulation. Therefore, the simulated high‐resolution atmospheric CO2 concentrations in East Asia in WRF‐Chem over 10 years are reliable data that resemble the observed values and could be highly valuable in understanding the carbon cycle in East Asia. [ABSTRACT FROM AUTHOR]
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- 2024
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16. Systemic Therapy of Gastric Cancer—State of the Art and Future Perspectives.
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Lordick, Florian, Rha, Sun Young, Muro, Kei, Yong, Wei Peng, and Lordick Obermannová, Radka
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THERAPEUTIC use of antineoplastic agents , *ESOPHAGEAL physiology , *ADENOCARCINOMA , *COMBINATION drug therapy , *HETEROCYCLIC compounds , *STOMACH tumors , *MEDICAL quality control , *CLINICAL trials , *IMMUNOTHERAPY , *PROGRAMMED death-ligand 1 , *ESOPHAGEAL tumors , *TREATMENT effectiveness , *CANCER patients , *TUMOR markers , *CONFERENCES & conventions , *ADJUVANT chemotherapy , *SURGICAL complications , *GENE expression , *METASTASIS , *ONCOGENES , *COMBINED modality therapy , *TUMOR classification , *SURVIVAL analysis (Biometry) , *PERIOPERATIVE care , *PLATINUM - Abstract
Simple Summary: A review of the latest research at PubMed and major cancer conferences was conducted to find out the current treatments for advanced stomach and esophagogastric junction cancers. In the West, neoadjuvant and perioperative chemotherapy is preferred for localized tumors. In East Asia, adjuvant chemotherapy is preferred. Studies are looking at how well immunotherapy and other drugs work in the perioperative setting. To choose the best treatment for advanced gastric cancer, including adenocarcinoma of the esophago-gastric junction, it is important to know biomarkers like HER2 expression, PD-L1 combined positive score (CPS), Claudin 18.2, and microsatellite instability (MSI). The standard first-line therapy is a combination of fluoropyrimidine and a platinum derivative. The choice of chemotherapy with antibodies depends on the biomarker. This article reviews recent clinical trial results and looks at the future of systemic therapy. Background: The prognosis of patients diagnosed with locally advanced and metastatic gastric and esophago-gastric junction cancer is critical. The optimal choice of systemic therapy is essential to optimize survival outcomes. Methods: A comprehensive literature review via PubMed and analysis of major oncology congresses (European Society for Medical Oncology and American Society of Clinical Oncology websites) were conducted to ascertain the current status and latest developments in the systemic treatment of patients with localized or advanced gastric and esophago-gastric junction adenocarcinoma. Results: While neoadjuvant and perioperative chemotherapy for localized tumor stages is the preferred approach in the Western Hemisphere, adjuvant chemotherapy remains the preferred course of action in East Asia. The administration of chemotherapy, typically in the form of combinations comprising platinum and fluoropyrimidine compounds in combination with docetaxel, represents a standard of care. Investigations are underway into the potential of immunotherapy and other biologically targeted agents in the perioperative setting. To select the most appropriate therapy for advanced gastric cancer, including adenocarcinoma of the esophago-gastric junction, it is essential to determine biomarkers such as HER2 expression, PD-L1 combined positive score (CPS) (combined positive score), Claudin 18.2, and microsatellite instability (MSI). In the present clinical context, the standard first-line therapy is a combination of fluoropyrimidine and a platinum derivative. The selection of chemotherapy in combination with antibodies is contingent upon the specific biomarker under consideration. Conclusions: This article reviews the current state of the art based on recent clinical trial results and provides an outlook on the future of systemic therapy. [ABSTRACT FROM AUTHOR]
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- 2024
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17. Childhood, Migration and the Pursuit of Happiness in MIDDLE‐CLASS EAST ASIA.
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Beck, Fanni, Nyíri, Pál, and Gaspar, Sofia
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MIDDLE class families , *POWER (Social sciences) , *EDUCATIONAL change , *PARENTS , *HAPPINESS - Abstract
This special issue explores the shifting landscape of global middle‐class migration within and from East Asia by taking the relationship between mobility, parenting ideals and changing educational desires as its focus. Contributions explore how East Asian middle‐class families balance the emergent emphasis on their children's well‐being with the demands of global competitiveness as these often‐antagonistic desires are projected onto old and new migration destinations against the background of global geopolitical and economic power shifts. Instead of reifying the simplistic binary of hierarchical, achievement‐oriented East Asian 'Confucian educational norms' versus democratic, well‐being‐focussed Western ideals, the contributions offer a nuanced understanding of how these educational ideals coexist within the social, cultural, political and economic contexts of families. By carefully assessing the dialectically entwined intimate experiences of parents and children, the articles collected here set out to broaden our understanding of how middle‐class families in Singapore, South Korea, Japan and China attempt to negotiate the tension between prioritizing children's happiness and maintaining global competitiveness result in a variety of strategies from migrating to less obvious international destinations to crafting domestic alternatives. Taken together, the articles reveal consistent patterns of middle‐class migration and child‐rearing decisions that contest and reshape conventional notions of success, attesting to a shift in global middle‐class migration trends and to the importance of child‐rearing in migratory decisions. [ABSTRACT FROM AUTHOR]
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- 2024
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18. First report of the genus Eggysodon from Asia.
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Lu, Xiaokang, Deng, Tao, Sun, Boyang, Hou, Yemao, Paul, Rummy, Sun, Danhui, and Li, Shijie
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PALEOGENE , *MANDIBLE , *ADULTS , *MAMMALS , *SPECIES - Abstract
We described a new pair of incomplete mandibles from the Qingshuiying locality, Northwest China, and referred it to Eggysodon, E. lingwuensis sp. nov. The new species has a typical mosaic assemblage of features: dp1 (or p1) is present at adult stage, but the symphysis is posteriorly elongated and the diastema distance between the canine and dp1 (or p1) is further shortened. In terms of the evolutionary stage, E. lingwuensis sp. nov. is more advanced than E. osborni, but comparable to that of E. gaudryi. Together with other mammals from the Qingshuiying locality, we suggested that the strata-produced new material was deposited during the Early Oligocene. On the other hand, the continental fauna exchange during the Palaeogene between Europe and Asia had very scarce records. Eggysodon has four species from the Oligocene of Europe. This record definitely confirmed that there is a migration route between Central Europe and East Asia during the Early Oligocene. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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19. Planning and construction of the British concessions and settlements in modern East Asia (1845–1876): Shanghai, Yokohama, and Tianjin.
- Author
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Sun, Shuting, Aoki, Nobuo, and Xu, Subin
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MODERNIZATION (Social science) , *CITIES & towns , *URBAN planning , *COLONIAL administration ,BRITISH colonies - Abstract
Under British informal imperial policy, East Asia's system of concessions and settlements rapidly spread and promoted modernization. Especially in the mid- to late nineteenth century, the formative phase of the concession system, Shanghai, Yokohama and Tianjin embraced modern Western urban planning and architectural ideas by implementing Land Regulations (LR). A comparison of institutions, policies and mutual influences resulting from British colonization in these three cities can reflect the intricate internal and external factors that shape their local modernization, which helps explain the urban development trajectory in East Asia. However, existing studies lack comprehensive comparative analysis, exploration of institutional motives for spatial formation and examination of correlations between urban management patterns. Therefore, this study aims to situate the relation between colonialism and modernization in East Asia through an analysis of promulgation process, content changes and spatial impact of LR, the fundamental law of the concessions. This study shows that LR had an inheritance influenced by Consul Alcock. Characteristics of modern urban planning emerged in management and space. The modernization process was shaped by the development of the British native urban governance system, changes in colonial policy and the different social contexts of China and Japan. [ABSTRACT FROM AUTHOR]
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- 2024
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20. A super sandstorm altered the abundance and composition of airborne bacteria in Beijing.
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Xia, Fanxuan, Chen, Zhuo, Tian, Enze, and Mo, Jinhan
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SANDSTORMS , *BUILT environment , *MICROBIOLOGICAL aerosols , *PARTICULATE matter , *POLYMERASE chain reaction , *AIR sampling , *ENVIRONMENTAL quality , *NUCLEOTIDE sequencing - Abstract
• In Beijing's super sandstorm 2021, 5700 amplicon sequence variants were detected. • Airborne bacteria in sandstorms were compared with the after-storm and haze days. • The sandstorm newly brought 10 pathogenic bacterial genera to the atmosphere. • Small bioaerosols (0.65–1.1 µm) were still suspended after the sandstorm subsided. Sandstorm, which injects generous newly emerging microbes into the atmosphere covering cities, adversely affects the air quality in built environments. However, few studies have examined the change of airborne bacteria during severe sandstorm events. In this work, we analyzed the airborne bacteria during one of the strongest sandstorms in East Asia on March 15th, 2021, which affected large areas of China and Mongolia. The characteristics of the sandstorm were compared with those of the subsequent clean and haze days. The composition of the bacterial community of air samples was investigated using quantitative polymerase chain reaction (qPCR) and high-throughput sequencing technology. During the sandstorm, the particulate matter (PM) concentration and bacterial richness were extremely high (PM 2.5 : 207 µg/m3; PM 10 : 1630 µg/m3; 5700 amplicon sequence variants/m3). In addition, the sandstorm brought 10 pathogenic bacterial genera to the atmosphere, posing a grave hazard to human health. As the sandstorm subsided, small bioaerosols (0.65–1.1 µm) with a similar bacterial community remained suspended in the atmosphere, bringing possible long-lasting health risks. [Display omitted] [ABSTRACT FROM AUTHOR]
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- 2024
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21. Paradoxes in intercultural communication, acculturation strategies and adaptation outcomes: international students in Hong Kong.
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Yu, Baohua and Wright, Ewan
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FOREIGN study , *FOREIGN students , *CROSS-cultural communication , *CLASSROOM environment , *ACCULTURATION ,WESTERN countries - Abstract
Traditional sending countries of international students in East Asia have emerged as increasingly desirable higher education destinations. Yet little is known about the experiences of international students in East Asia as most research focuses on those in the Anglophone West. In this study, we explored the trajectory and interactions between intercultural communication, acculturation strategies, and adaptation outcomes of international students in Hong Kong. We conducted in-depth interviews with international students from other Asian countries (
n = 14) and Western countries (n = 10). Our research reveals a paradox where international students’ eagerness to engage with diverse peers is overshadowed by limited interaction with local students. Cultural and language differences were perceived to create a wall separating them from the local students, inhibiting a cosmopolitan learning environment. Additionally, international students often gravitate towards familiar national or cultural groups, which can hinder broader integration. Sociocultural challenges and outsider feelings were also reported, potentially leading to psychological issues. We propose an interactive framework that connects intercultural communication, acculturation strategies, and adaptation outcomes. The paper offers theoretical and practical insights for policymakers, administrators, educators, and students, aiming to foster effective communication and successful acculturation in a multilingual and multicultural educational setting. [ABSTRACT FROM AUTHOR]- Published
- 2024
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22. Traces of Bronze Age globalization in East Asia: Insights from a revised phylogeography of the Y‐chromosome haplogroup Q1a1a‐M120.
- Author
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Mai, La‐Su, Zhang, Xian‐Peng, Liu, Kai‐Jun, Ma, Peng‐Cheng, Li, Hui, Sun, Jin, and Wei, Lan‐Hai
- Subjects
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BRONZE Age , *GENOMIC imprinting , *TREE age , *STATE formation , *Y chromosome ,CHINESE civilization - Abstract
Objective Methods Results Conclusion In this study, we aim to explore the genetic imprint of Bronze Age globalization in East Asia from a phylogeographic perspective by examining the Y‐chromosome haplogroup Q1a1a‐M120, and to identify key demographic processes involved in the formation of early China and the ancient Huaxia people.Over the past few decades, we have collected the sequences of 347 Y chromosomes from the haplogroup Q1a1a‐M120. These sequences were utilized to analyze and reconstruct a highly revised phylogenetic tree with age estimates. And we analyzed the geographical distribution and spatial autocorrelation of nine major sub‐branches of Q1a1a‐M120. Finally, we observed the expansion of Q1a1a‐M120 from the beginning of the Bronze Age in East Asia, along with the continuous dissemination of its sub‐lineages among East Asian populations.We suggest that certain sub‐lineages played a significant role in the formation of states and early civilizations in China, as well as in the development of the ancient Huaxia people, who are the direct ancestors of the Han population. Overall, we propose that haplogroup Q‐M120 played a role in the introduction of Bronze Age culture to the central region of East Asia. Therefore, it is haplogroup Q‐M120, rather than the Western Eurasian paternal lineage, that expanded and contributed to the gene pool of the East Asian population.In summary, the globalization of the Bronze Age led to large‐scale population replacement and admixture across various regions of Eurasia; our findings highlight the unique demographic processes that occurred in East Asia during this period. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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23. Comparative plastome analyses and evolutionary relationships of 25 East Asian species within the medicinal plant genus Scrophularia (Scrophulariaceae).
- Author
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Xia Wang, Lei Guo, Lulu Ding, Leopoldo Medina, Ruihong Wang, and Pan Li
- Subjects
GERMPLASM ,MEDICINAL plants ,INDUSTRIALIZATION ,SCROPHULARIACEAE ,CHLOROPLAST DNA - Abstract
Background: Scrophularia L., a genus of the Scrophulariaceae, is a group of important medicinal plants used for eliminating heat and detoxifying. East Asia has an abundance of potentially medicinal Scrophularia species, and it serves as a secondary diversity center of the genus. However, the genomic resources available for germplasm identification and pharmaceutical exploration of East Asian Scrophularia are insufficient, hindering its commercial and industrial development. Additionally, the interspecific relationships of most East Asian Scrophularia species remain unclear. Methods: In this study, we sequenced the leaves of 25 East Asian species of the genus Scrophularia, assembled and annotated the complete chloroplast genomes, and subsequently performed comparative and phylogenetic analyses on these genomes. Results and discussion: The conserved plastome length of these 25 species ranged from 151,582 bp to 153,239 bp, containing a total of 132 coding genes, including 18 duplicated genes and 114 unique genes. Through genome alignment of these 25 species, 38-53 repeated sequences and 7 shared SSRs were identified, along with regions with high nucleotide polymorphism (Pi), which could potentially serve as molecular markers for species identification. The genome structure, gene content, and arrangement showed conservation, while variations were observed in the IR boundary regions and IGS. Phylogenetic inferences based on whole plastomes or on coding sequences (CDS) only yielded congruent results. We categorized the 25 East Asian Scrophularia species into six distinct clades and further explored their interspecies relationships using morphological characteristics, such as flower color, the relative position of stamens and corolla, and plant height. This could lay a genetic basis for future resource development of Scrophularia in East Asia. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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24. KORE-Map 1.0: Korean medicine Omics Resource Extension Map on transcriptome data of tonifying herbal medicine.
- Author
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Park, Musun, Park, Sang-Min, Lee, Haeseung, Kim, Aeyung, Kim, No Soo, Kim, Yu Ri, Yi, Jin-Mu, and Cha, Seongwon
- Subjects
HERBAL medicine ,TRANSCRIPTOMES ,INCURABLE diseases ,TRADITIONAL medicine ,DRUG target - Abstract
Traditional herbal medicine, rooted in a long history of use in East Asia, combines several herbs to create treatments showing high efficacy with minimal side effects, for specific diseases. Such combination therapies represent a potential reservoir of new drugs for treating multifactorial and incurable chronic diseases. However, the complexity of their mechanisms of action due to the combination of multiple compounds, has limited their research integration into modern pharmacological science. To address this challenge, we constructed drug-induced transcriptome data for herbal medicines through systematic experiments, analyzed with the aid of various omics databases. We introduce KORE-Map 1.0 (Korean medicine Omics Resource Extension Map), the first comprehensive resource of drug-derived transcriptome data for representative tonifying herbal medicines, effective in enhancing the immune system. This dataset aims to provide novel insights into the combinatorial mechanisms of these herbal medicines and to aid in the discovery of new therapeutic targets and indications for various incurable diseases. [ABSTRACT FROM AUTHOR]
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- 2024
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25. Electrical conductivity of mantle minerals beneath East Asia revealed by geomagnetic observatory data.
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Zhang, Yuyan, Ma, Mina, Hu, Yujia, Han, Yiliang, and Zhang, Yanhui
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EARTH'S mantle ,ELECTRIC conductivity ,MANTLE plumes ,DEPTH sounding ,ISLAND arcs - Abstract
The electrical conductivity of the earth's mantle can provide important information about geodynamic phenomena. East Asia is associated with complex tectonics and geodynamic processes. Hence, it is necessary to better understand the deep structure beneath East Asia. In this study, geomagnetic data obtained from East Asian observatories are employed to image the conductivity structure of the mantle at depths ranging from 410 to 900 km. First, the data are processed using the modified bounded influence remote reference processing (BIRRP) method and the ratio method is used to correct for the ocean effect. Thereafter, the stable C-response curves at the 27 observatories are estimated, and 1D electrical conductivity models for these observatories are established using the L-BFGS method. The conductivity-depth profiles reveal a heterogeneous distribution of the electrical conductivity beneath East Asia. The mantle transition zone (MTZ) beneath East China and Japan is found to be more conductive, whereas the MTZ beneath central and southern regions of China is more resistive. In East China, the dehydration of the stagnant Pacific slab may lead to an increase in the conductivity of the mantle minerals. There is also the possibility of upwelling of the thermal material from the lower mantle beneath the Japanese Island arc. In Northwest China, there exists a large high-conductive body beneath the Tarim area, which could indicate an upwelling of the Tarim mantle plume. Our results provide insights into the deep structure of the earth at the mantle scale. [ABSTRACT FROM AUTHOR]
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- 2024
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26. The carrot and the stick: China's wedging against South Korea during the US–China competition.
- Author
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Lee, Kihyun and Kwon, Jaebeom
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- *
GREAT powers (International relations) , *PARK management , *POWER (Social sciences) , *COMPUTER network security , *WEDGES - Abstract
In the midst of an intensifying US–China competition, China has adopted various policies to deal with the expanding US-led security network encircling it. As one endeavour, China has implemented a wedge strategy to weaken the US-led security coalition. This study focuses on one case of China's wedging against South Korea to disturb the US-South Korea alliance. This wedging strategy against the Park Geun-hye Administration was composed of two distinct approaches: a reward-based general wedging to prevent South Korea from tilting toward the US, and a coercion-based issue-specific wedging to divide them primarily by disturbing the deployment of THAAD in Korea. [ABSTRACT FROM AUTHOR]
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- 2024
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27. The disease burden of bladder cancer and its attributable risk factors in five Eastern Asian countries, 1990–2019: a population-based comparative study.
- Author
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Luo, Li-Sha, Luan, Hang-Hang, Zhang, Ping, Jiang, Jun-Feng, Zeng, Xian-Tao, Huang, Jiao, and Jin, Ying-Hui
- Subjects
- *
GLOBAL burden of disease , *BLADDER cancer , *DEATH rate , *BLADDER diseases , *SMOKING - Abstract
Backgrounds: The study aimed to estimate bladder cancer burden and its attributable risk factors in China, Japan, South Korea, North Korea and Mongolia from 1990 to 2019, to discuss the potential causes of the disparities. Methods: Data were obtained from the Global Burden of Disease Study 2019. The annual percent change (APC) and average annual percent change (AAPC) were calculated by Joinpoint analysis, and the independent age, period and cohort effects were estimated by age-period-cohort analysis. Results: In 2019, the highest incidence (7.70 per 100,000) and prevalence (51.09 per 100,000) rates of bladder cancer were in Japan, while the highest mortality (2.31 per 100,000) and DALY rates (41.88 per 100,000) were in South Korea and China, respectively. From 1990 to 2019, the age-standardized incidence and prevalence rates increased in China, Japan and South Korea (AAPC > 0) and decreased in Mongolia (AAPC < 0), while mortality and DALY rates decreased in all five countries (AAPC < 0). Age effects showed increasing trends for incidence, mortality and DALY rates, while the prevalence rates increased first and then decreased in older groups. The cohort effects showed downward trends from 1914–1918 to 2004–2008. Smoking was the greatest contributor and males had the higher burden than females. Conclusion: Bladder cancer was still a major public health problem in East Asia. Male and older population suffered from higher risk, and smoking played an important role. It is recommended that more efficient preventions and interventions should be operated among high-risk populations, thereby reduce bladder cancer burden in East Asia. [ABSTRACT FROM AUTHOR]
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- 2024
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28. Acute kidney injury as a prognostic marker in severe fever with thrombocytopenia syndrome.
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Lee, Jin Mi, Kim, Hae Lee, Lim, Myoung-nam, Kim, Changhyup, La, Yeon Ju, Jeon, Yong Duk, Oh, Won Sup, Son, Seongmin, Lee, Sunhwa, Baek, Hyunjeong, Hwang, Daniel Duck-Jin, and Park, Ji In
- Subjects
- *
FEVER , *ACUTE kidney failure , *PROGNOSIS , *TICK-borne diseases , *THROMBOCYTOPENIA ,MORTALITY risk factors - Abstract
Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne illness with a notable morality risk that is becoming increasingly prevalent in East Asia (14–36%). Increasing evidence indicates a more direct role of the SFTS virus in renal impairment. However, few studies have explored the risk factors for and clinical outcomes of AKI in patients with SFTS. Therefore, in this study, we aimed to investigate risk factors and outcomes associated with AKI in patients with SFTS. In this retrospective cohort study, we included the data of 53 patients who were diagnosed with SFTS virus infection at Kangwon National University Hospital between 2016 and 2020. We incorporated laboratory data and medical information including comorbidities, complications, and mortality. Baseline characteristics, clinical features, laboratory parameters, and mortality rates of the non-AKI and AKI groups were compared. Patient survival of non-AKI and AKI groups were compared using the Kaplan–Meier method. To identify the population with poor prognosis, Cox regression analysis was used to identify the independent risk factors for in-hospital mortality in patients with SFTS. Of the 53 individuals, 29 (54.7%) were male, with an average age of 66.5 years. Nine patients (15.1%) died of SFTS. Twenty-seven (50.9%) patients exhibited AKI; the average time interval from fever onset to AKI occurrence was 3.6 days. Notably, 24 (88.9%) patients developed AKI within the first week of fever onset. Patients in the AKI group exhibited a significantly higher prevalence of diabetes and were older than those in the non-AKI group. The mortality rate was notably higher (29.6%) in the AKI group than in the non-AKI group (3.8%). Within the AKI cohort, advanced stages (stages 2 and 3) showed a 50% mortality rate, which was significantly higher than the 17.6% mortality rate in patients with stage 1 AKI. Additionally, Kaplan–Meier curves revealed lower survival rates among patients with AKI than among those without AKI (P = 0.017). Cox regression analysis identified leukopenia and elevated serum creatinine levels as significant risk factors for mortality. AKI is a common complication associated with SFTS. Moreover, the mortality rate was significantly higher in the patients who developed AKI than in those who did not. Our findings underscore the pivotal role of AKI as a prognostic marker of disease severity in patients with SFTS. [ABSTRACT FROM AUTHOR]
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- 2024
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29. Multiple glacial refugia during Pleistocene climatic oscillations shape the genetic pattern of Machilus thunbergii across East Asia.
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Jiang, Kai, Xiao, Yue-E, Gaitán-Espitía, Juan Diego, Wang, Zhengwei, Yu, Shuo, Wang, Rong, Hu, Yonghong, Huang, Weichang, and Chen, Xiaoyong
- Subjects
- *
SUBMERGED lands , *MICROSATELLITE repeats , *GLACIATION , *POLLEN dispersal , *SEED dispersal , *CHLOROPLAST DNA - Abstract
Pleistocene climatic oscillations caused periodic decline and rise of sea levels, leading to dispersion and retraction cycles of island flora. Yet, the role of island refugia in the current Sino-Japanese Floristic Region remains poorly understood. In this study, we investigated the population genetic structure of the widespread Sino-Japanese Floristic Region tree Machilus thunbergii to infer the potential impact of island refugia. We collected 1378 samples from 64 locations across the distribution ranges. Using chloroplast DNA and microsatellite markers, we found a pronounced genetic differentiation between mainland and island populations, which can be divided further into two and three groups, respectively. Furthermore, comparable numbers of private alleles and haplotypes are present in both mainland and island populations. No essential current gene flow was detected between mainland and island populations after their separation 14 000 years ago. Such patterns are hypothesized to result from the influence of multiple glacial island refugia during Pleistocene climatic oscillations, with limited pollen and seed dispersal of the species. Our findings underscore that the islands and submerged land bridge can act as refugia for plants during glacial periods and have essentially shaped the genetic structure of M. thunbergii populations. [ABSTRACT FROM AUTHOR]
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- 2024
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30. Morphological and functional evolution of gametophytes in epilithic Hymenasplenium murakami-hatanakae (Aspleniaceae): The fifth family capable of producing the independent gametophytes.
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Yoneoka, Katsuhiro, Fujiwara, Tao, Kataoka, Toshifumi, Hori, Kiyotaka, Ebihara, Atsushi, and Murakami, Noriaki
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- *
GAMETOPHYTES , *DNA analysis , *PTERIDACEAE , *SPORES , *FERNS , *CHLOROPLAST DNA - Abstract
The fern independent gametophytes that can maintain populations by vegetative reproduction without conspecific sporophytes have been considered an unusual phenomenon found in some epiphytic or epilithic species of Hymenophyllaceae, Pteridaceae, Lomariopsidaceae, and Polypodiaceae. By chance, the discovery of mysterious strap-like gametophytes on Izu-Oshima Island, Japan, has led to the hypothesis that Hymenasplenium murakami-hatanakae, a fern species belonging to Aspleniaceae, can also form independent gametophytes. Our investigation revealed gametophyte populations of H. murakami-hatanakae on three islands in the Izu Islands. Based on chloroplast DNA analysis of the gametophyte and sporophyte populations, the gametophytes were found to be maintained by vegetative reproduction without a new supply of spores from sporophytes. A comparison of the surrounding vegetation at the collection sites showed that environmental factors such as light and humidity may influence the maintenance of gametophyte populations. These results clearly show that H. murakami-hatanakae is one of the ferns capable of forming independent gametophytes. This is the first report of independent gametophytes from the suborder Aspleniineae (eupolypod II). The discovery of the independent gametophyte within a phylogenetic lineage previously thought not to form independent gametophytes will provide important insights into the morphological and functional evolution of gametophytes in ferns. [ABSTRACT FROM AUTHOR]
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- 2024
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31. Japan's Revolutionary Military Change: Explaining Why It Happened Under Kishida.
- Author
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Ayumi Teraoka and Ryo Sahashi
- Subjects
- *
MILITARY budgets , *REVOLUTIONARIES , *INTERNATIONAL security , *MILITARY policy , *DOMESTIC violence , *POSTURE - Abstract
Japan's security policy is changing rapidly, with drastic increases to its defense budget and the acquisition of counterstrike capabilities. While the deteriorating security environment undeniably motivates Japan's defense posture, the speed and extent of these recent changes still present a puzzle. Why was it under Kishida Fumio--a former leader of Kōchikai, the liberal and oft-considered pacifist faction within the Liberal Democratic Party (LDP)--that Japan achieved its watershed moment on defense? This article explains this change through the exigencies of Kishida's domestic political survival. It was through his leadership of a minority faction within the LDP, his image as a dove, and support for fiscal discipline, that Kishida managed to find the largest common denominator among competing domestic political forces. Had it not been for Kishida, the speed and degree of Japan's recent transformation in security policies would have been unlikely. In light of these findings, we conclude by considering the policy implications for understanding Japan's security posture. [ABSTRACT FROM AUTHOR]
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- 2024
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32. U.S.-China Technology Competition and the Emergence of Techno-Economic Statecraft in East Asia: High Technology and Economic-Security Nexus.
- Author
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Lee, Seungjoo
- Subjects
- *
HIGH technology , *HIGH technology industries , *SUPPLY chains , *SELF-reliant living ,CHINA-United States relations - Abstract
This study posits that U.S.-China technology competition has promoted the spread of techno-economic statecraft in East Asia. The emergence of techno-economic statecraft in East Asia requires systematic analysis because it affects not only the dynamics of U.S.-China technology competition but also the restructuring of the regional order. Since both the United States and China do not have complete self-sufficiency in the high-tech innovation ecosystem, it has become an urgent task for them to reduce their vulnerability to winning technological competition. Against this backdrop, East Asian countries have emerged as actors playing an important role in technological competition. Since East Asian countries are key players in the supply chain of high-tech industries, cooperation with East Asian countries has emerged as a factor that can influence the landscape of U.S.-China technology competition. Based on these observations, this study aims to explain the following four phenomena: First, it explains the process by which the United States and China seek to securitize high technology as a means of reducing their own structural vulnerabilities while redrawing new boundaries for cooperation with East Asian countries. Second, I argue that U.S.-China technology competition has accelerated the rise of techno-economic statecraft in East Asia. Third, I assert that there are significant differences in the techno-economic statecraft pursued by East Asian countries in the U.S.-China technology competition. Fourth, the divergence of techno-economic statecraft in East Asian countries has created systemic effects in the regional order. [ABSTRACT FROM AUTHOR]
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- 2024
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33. The Use and Misuse of East Asian History in IR Theorizing.
- Author
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Chen, Zheng
- Subjects
- *
ASIAN history , *HISTORICAL sociology , *ETHNOCENTRISM - Abstract
The past two decades have witnessed a wave of research into the history of East Asian international relations (IR). Scholars seek to broaden the historical frames of reference in IR for both theory testing and theory generation. The article reviews this recent trend, examining its limitations and exploring future agenda. In studying historical East Asian IR, scholars have different expectations regarding whether their research would support, complement, or undermine mainstream Western IR. The spatial and temporal scope of their historical inquiries, as well as theoretical ambitions, therefore, differ significantly. Scholars no longer treat all East Asian history as simply one case, but as multiple cases with divergent patterns, and they recognize that the system consisted not solely of China but of multiple actors. In addition to contrasting East Asia with Western Europe, they explore also the similarities between East Asia and other non-Western regions. To advance the agenda, however, scholars must scrupulously navigate three tensions. They are: the tension between the "East" and "West"; the tension between the two disciplines of history and IR; and the tension between past and present. Future studies, therefore, must broaden their horizons in order to better transcend ethnocentrism and exceptionalism, refine their methodology both to avoid selection bias and conduct more sophisticated comparisons, and to maintain a proper distance from contemporary politics. Most importantly, they should combine high-quality historical research with cutting-edge IR theoretical trends to construct dynamic theories that could be applied to other regions. [ABSTRACT FROM AUTHOR]
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- 2024
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34. Integrative taxonomy of an East Asian songbird indicates rapid dwarfism after island colonization.
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Wei, Chentao, Peng, Lanhui, Zhang, Yanyun, Nishiumi, Isao, Carey, Geoff J., Liu, Zongzhuang, Alström, Per, Dong, Lu, and Liu, Yang
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- *
BIOLOGICAL classification , *GENETIC variation , *BODY size , *ARCHIPELAGOES , *RELATIONSHIP status - Abstract
Animals that colonize islands often undergo significant evolutionary changes in comparison with their continental counterparts as a response to specific island conditions. The pace of such changes can be relatively fast, which poses challenges in the evaluation of the taxonomic status of island taxa. The Japanese and Manchurian Bush Warbler species complex (Horornis diphone–canturians), which breeds in East Asia and the Japanese Archipelago, is such an avian example. This species complex exhibits significant morphological differentiation between different taxa, and the taxonomic status and phylogenetic relationships within the complex are debated. Here, we updated the taxonomy of this species complex and shed insight on its evolutionary history using multi‐locus phylogeographic and acoustic analyses. Our results support the conventional treatment of the two continental taxa borealis and canturians as subspecies of H. canturians, contrary to some recent proposals that they are affiliated to H. diphone. We also document a reduction in body size, that is dwarfism, and vocal divergence in the nominate subspecies H. d. diphone, which is endemic to the remote and isolated Ogasawara Islands. These changes may have happened following colonization of these islands, which was estimated to have taken place approximately 0.2 million years ago. Although H. d. diphone is clearly distinctive and deserves recognition as an evolutionarily significant unit, H. d. diphone and other H. diphone samples were not reciprocally monophyletic. Because of this lack of reciprocal monophyly and a relatively recent divergence time, we advocate maintaining its current subspecies status. We also detected reduced genetic diversity, measured as heterozygosity, in H. d. diphone. We suggest that conservation efforts in the Ogasawara Islands should prioritize the protection of this endemic subspecies. Collectively, our findings suggest that the separation between the populations on the East Asian continent and the Japanese Archipelago, followed by colonization of remote oceanic islands through long‐distance dispersal, underlie rapid phenotypic and genetic diversification of the Horornis diphone–canturians species complex. [ABSTRACT FROM AUTHOR]
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- 2024
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35. The Metamorphosis of the Novel Moment in Peking in Japan, Taiwan, and China.
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YUAN Gao
- Subjects
LITERATURE translations ,POWER (Social sciences) ,WAR ,METAMORPHOSIS ,CENSORSHIP - Abstract
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- 2024
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36. Trastuzumab deruxtecan versus trastuzumab emtansine in Asian patients with HER2‐positive metastatic breast cancer.
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Iwata, Hiroji, Xu, Binghe, Kim, Sung‐Bae, Chung, Wei‐Pang, Park, Yeon Hee, Kim, Min Hwan, Tseng, Ling‐Ming, Chung, Chi‐Feng, Huang, Chiun‐Sheng, Kim, Jee Hyun, Chiu, Joanne Wing Yan, Yamashita, Toshinari, Li, Wei, Egorov, Anton, Nishijima, Soichiro, Nakatani, Shunsuke, Nishiyama, Yuji, Sugihara, Masahiro, Cortés, Javier, and Im, Seock‐Ah
- Abstract
The global phase 3 DESTINY‐Breast03 study (ClinicalTrials.gov; NCT03529110) showed statistically significant and clinically meaningful improvements in progression‐free survival (PFS) and overall survival (OS) with trastuzumab deruxtecan (T‐DXd) over trastuzumab emtansine (T‐DM1) in patients with human epidermal growth factor receptor 2 (HER2)‐positive metastatic breast cancer (mBC) previously treated with trastuzumab and a taxane. Here, we report a subgroup analysis of Asian patients enrolled in DESTINY‐Breast03. In total, 309 patients (149 in the T‐DXd arm and 160 in the T‐DM1 arm) from Asian countries and regions were randomized. At data cutoff (July 25, 2022), the median duration of follow‐up in the Asian subpopulation was 29.0 months with T‐DXd and 26.0 months with T‐DM1. The PFS (determined by blinded independent central review) hazard ratio was 0.30 (95% confidence interval 0.22–0.41) favoring T‐DXd over T‐DM1 (median PFS 25.1 vs. 5.4 months). Median OS was not reached in the T‐DXd arm and was 37.7 months in the T‐DM1 arm. The median treatment duration was 15.4 months with T‐DXd and 5.5 months with T‐DM1. The incidence of grade ≥3 drug‐related treatment‐emergent adverse events was similar between both treatment arms (49.0% vs. 46.5%) and was consistent with the overall DESTINY‐Breast03 population. Adjudicated drug‐related interstitial lung disease or pneumonitis occurred in 12.9% of patients treated with T‐DXd and 2.5% treated with T‐DM1, with a higher incidence in Japanese patients; none of these were grade ≥4 events. These efficacy and safety data reinforce the favorable benefit–risk profile of T‐DXd in HER2‐positive mBC, including in the Asian subgroup. [ABSTRACT FROM AUTHOR]
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- 2024
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37. Application of Multiple Geophysical Exploration Methods in the Exploration of Marine Sand Resources in the Northern Offshore Waters of the South China Sea.
- Author
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Yu, Gang, Hu, Xichong, Fang, Jie, Yang, Ying, Zhang, Yongcong, Lin, Jinhui, Liu, Jingyi, and Qian, Libing
- Subjects
MARINE sediments ,GEOPHYSICAL prospecting ,OCEAN bottom ,MARINE resources ,SEISMIC surveys - Abstract
Marine sand, in addition to oil and gas resources, is the second-largest marine mineral resource. The rational development and utilization of marine sand resources are conducive to the growth of the marine economy. In the process of marketing marine sand in China, local authorities are required to delineate auctioned sand mining areas after a general survey, commonly referred to as preliminary exploration. Marine sand can be categorized into surface marine sand and buried marine sand. Buried marine sand deposits are buried beneath the sea floor, making it challenging to locate them due to their thin thickness. Consequently, there exist numerous technical difficulties associated with marine sand exploration. We conducted the preliminary research work in the waters off Guangdong Province of the South China Sea, employing a reduced drilling and identifying a potentially extensive deposit of marine sand ore. In this study, various geophysical methods such as sub-bottom profile survey, single-channel seismic survey, and drilling engineering were employed in the northern offshore waters of the South China Sea. As a result, two distinct marine sand bodies were delineated within the study area. Additionally, five reflective interfaces (R
1 , R2 , R3 , R4 , and R5 ) were identified from top to bottom. These interfaces can be divided into five seismic sequences: A1 , B1 , C1 , D1 , and E1 , respectively. Three sets of strata were recognized: the Holocene Marine facies sediment layer (Q4 m ), the Pleistocene alluvial and pluvial facies sediment layer (Q3 al+pl ), as well as the Pleistocene Marine facies sedimentary layer (Q3 m ). In total, two placers containing marine sand have been discovered during this study. We estimated the volume of marine sand and achieved highly favorable results of the concept that we are proposing a geologic exploration approach that does not involve any previous outcropping analogue study. [ABSTRACT FROM AUTHOR]- Published
- 2024
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38. Problems accessing health care and under-5 mortality: a pooled analysis of 50 low- and middle-income countries.
- Author
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Kim, Jinseo, Eom, Yun-Jung, Ko, Soohyeon, Subramanian, S V, and Kim, Rockli
- Subjects
HEALTH services accessibility ,MIDDLE-income countries ,RESEARCH funding ,MULTIPLE regression analysis ,MOTHERS ,CHILD mortality ,DESCRIPTIVE statistics ,CHI-squared test ,SURVEYS ,TRANSPORTATION ,ODDS ratio ,ANALYSIS of variance ,CONFIDENCE intervals ,LOW-income countries ,MEDICAL care costs - Abstract
Background Access to health care remains suboptimal in low- and middle-income countries (LMICs) and continues to hinder survival in early childhood. We systematically assessed the association between problems accessing health care (PAHC) and under-five mortality (U5M). Methods Child mortality data on 724 335 livebirths came from the latest Demographic and Health Surveys of 50 LMICs (2013–2021). Reasons for PAHC were classified into three domains: 'money needed for treatment' (economic), 'distance to health facility' (physical), 'getting permission' or 'not wanting to go alone' (socio-cultural). Multivariable logistic regression was used to estimate the association between PAHC (any and by each type) and U5M. Results In our pooled sample, 47.3 children per 1000 livebirths died before age of 5, and 57.1% reported having experienced PAHC (ranging from 45.3% in Europe & Central Asia to 72.7% in Latin America & Caribbean). Children with any PAHC had higher odds of U5M (OR: 1.05, 95% CI: 1.02, 1.09), and this association was especially significant in sub-Saharan Africa. Of different domains of PAHC, socio-cultural PAHC was found to be most significant. Conclusions Access to health care in LMICs needs to be improved by expanding health care coverage, building health facilities, and focusing more on context-specific socio-cultural barriers. [ABSTRACT FROM AUTHOR]
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- 2024
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39. Simmering Storm in the East China Sea: Shifting Dynamics in the Great Power Rivalries of East Asia.
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Mason, Ra and Park, Soul
- Subjects
CONFIRMATION bias ,INTERNATIONAL relations ,CHINA-Japan relations - Abstract
The East China Sea (ECS) is one of the region's most significant and oft-times under-addressed potential flashpoints. In this article we take a holistic approach and reexamine the recent actions of East Asia's two most significant powers, China and Japan, in relation to this important body of maritime space, as well as those of the United States (US), as the incumbent regional hegemon. Specifically, we examine the efficacy of each. This highlights a dynamism in Chinese actions, as well as elucidating how the US and Japan have come to adopt policies that are of dubious efficacy as a means of alleviating or nullifying the escalation of unwanted tensions across the ECS. In so doing, we draw upon two key concepts, immobilism and confirmation bias, that help us to understand why the US and Japan are failing to achieve their assumed objectives of regional stability and the maintenance of the status quo. Ultimately, we argue that a combination of immobilism and confirmation bias in American and Japanese foreign policy, in response to the greater dynamism and adaptability of regional great powers such as China, has led to latent changes in the status quo that risk undermining stability across the ECS. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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- View/download PDF
40. Clinical Efficacy and Safety of Anti-Obesity Medications Among Adult East Asian People with Obesity: A Systematic Literature Review and Indirect Treatment Comparison.
- Author
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Yokote, Koutaro, Ota, Riku, Wada, Shogo, Matsuda, Hiroyuki, and Filomeno, Ronald
- Abstract
Introduction: The prevalence of obesity has increased worldwide over the past decades. Regional variations exist in the relationship between body mass index (BMI), body fat, and health risks: Asians typically have a lower BMI than people of European descent, but a higher risk of obesity-related comorbidities. However, there is a paucity of evidence for anti-obesity medications (AOMs) in East Asian populations. In this study, we aimed to systematically review evidence regarding the safety and efficacy of AOMs among adults with obesity disease in East Asia, and to assess the feasibility of conducting an indirect treatment comparison (ITC) between the semaglutide and mazindol trials. Methods: The Embase, MEDLINE, and ICHUSHI databases were searched via the Ovid SP platform for randomized controlled trials, in English or Japanese, reporting data on semaglutide or mazindol therapy with placebo or diet and exercise as comparators. The potential risks of bias in conducting a population-adjusted ITC were determined based on the heterogeneity of potential effect modifiers and variations in study design. Results: Of 21 publications, 2 were included in this study based on the eligibility criteria. The STEP 6 study established the clinical efficacy of subcutaneous semaglutide compared with placebo in the reduction of body weight and cardiometabolic risk factors [glycated hemoglobin (HbA
1c ), total cholesterol, and systolic blood pressure] among Japanese and South Korean people with obesity disease. Mazindol also proved beneficial in reducing body weight and total cholesterol compared with placebo in Japan. Both semaglutide and mazindol were associated with higher rates of adverse events and treatment discontinuation than placebo. An ITC between the two studies was not deemed feasible based on the potential risks of bias. Conclusions: Semaglutide and mazindol are associated with significant body weight reduction among people with obesity in East Asia. Further research based on label indications and up-to-date real-world data among East Asian people with obesity would help determine additional clinical benefits. [ABSTRACT FROM AUTHOR]- Published
- 2024
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41. Synergistic effects of Pleistocene geological and climatic events on complex phylogeographic history of widespread sympatric species of Megaloptera in East Asia.
- Author
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Ai-Li Lin, Ming-Ming Zou, Li-Jun Cao, Fumio Hayashi, Ding Yang, and Xing-Yue Liu
- Subjects
AQUATIC insects ,PLEISTOCENE Epoch ,BIOGEOGRAPHY ,VICARIANCE ,GLACIATION - Abstract
Unraveling the phylogeographic histories of species remains a key endeavor for comprehending the evolutionary processes contributing to the rich biodiversity and high endemism found in East Asia. In this study, we explored the phylogeographic patterns and demographic histories of three endemic fishfly and dobsonfly species (Neochauliodes formosanus, Protohermes costalis, and Neoneuromus orientalis) belonging to the holometabolan order Megaloptera. These species, which share a broad and largely overlapping distribution, were analyzed using comprehensive mitogenomic data. Our findings revealed a consistent influence of vicariance on the population isolation of Neoc. formosanus and P. costalis between Hainan, Taiwan, and the East Asian mainland during the early Pleistocene, potentially hindering subsequent colonization of the later diverged Neon. orientalis to these islands. Additionally, we unveiled the dual function of the major mountain ranges in East Asia, serving both as barriers and conduits, in shaping the population structure of all three species. Notably, we demonstrated that these co-distributed species originated from Southwest, Southern, and eastern Central China, respectively, then subsequently migrated along multi-directional routes, leading to their sympatric distribution on the East Asian mainland. Furthermore, our results highlighted the significance of Pleistocene land bridges along the eastern coast of East Asia in facilitating the dispersal of mountain-dwelling insects with low dispersal ability. Overall, this study provides novel insight into the synergistic impact of Pleistocene geological and climatic events in shaping the diversity and distribution of aquatic insects in East Asia. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
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42. US Imperialism and its Legacies in East Asia: Thucydides Trap or Thrasymachus Paradox?
- Author
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Maritan, Mario
- Abstract
The US presence in East Asia is not simply a result of the victory over Japan in WW2, but a legacy of the US takeover of the Spanish overseas empire in 1898. Today, the threat of war between China and the US has little to do with Allison's Thucydides trap, which is based on a misreading of Thucydides' work: It originates from what in China is seen as a US imperial presence that mirrors Western interference in Chinese affairs during the so-called "century of humiliation." China is an authoritarian state with regional hegemonic ambitions, yet the West has been endorsing other authoritarian states, even absolute monarchies, that fit its geopolitical interests. Notwithstanding the purported US support of "freedom" and "democracy," the US in East Asia has been carrying out a foreign policy that, as an extension of misinterpretations of the Monroe Doctrine, is a legacy of empire. This legacy is too often overlooked, while overseas interests are justified on the basis of security concerns. Thucydides is relevant, but to compare the American and Athenian empires and their demise, not to drag China into US geopolitical discourse, when focus should have long been on Russia. Anti-colonial theory shows how interstate relations, in particular in the East Asian context, are not defined by Thucydides trap, but Thrasymachus paradox. [ABSTRACT FROM AUTHOR]
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- 2024
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43. Vertical profile measurements for ammonia in a Japanese deciduous forest using denuder sampling technique: ammonia emissions near the forest floor
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Mao Xu, Ryota Matsumoto, Phuvasa Chanonmuang, and Kazuhide Matsuda
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NH3 ,Nitrogen ,Dry deposition ,Bidirectional exchange ,Long-term measurement ,East Asia ,Environmental technology. Sanitary engineering ,TD1-1066 ,Environmental sciences ,GE1-350 - Abstract
Abstract Ammonia (NH3) has received considerable attention as a major reduced nitrogen. However, accurate estimates of the deposition amount are difficult due to its complex behavior characterized by bidirectional exchange between the atmosphere and the surface. We observed the vertical profile of NH3 concentration in a deciduous forest in Japan for 1 year to further advance the studies on NH3 bidirectional exchange in Asia, especially focusing on the process near the forest floor. The observation period lasted from September 29, 2020, to September 28, 2021, including leafy and leafless periods. Using the denuder sampling technique, we measured NH3 concentration in the forest at three heights (above the forest canopy, 30 m, and near the forest floor, 2 m and 0.2 m). NH3 concentrations tended to be highest at the top of the canopy (30 m). Focusing on the concentration near the forest floor, the concentrations at 0.2 m were frequently higher than those at 2 m regardless of the leafy and leafless period, thus suggesting NH3 emissions from the forest floor. NH3 concentration near the forest floor showed strong positive correlations with air temperature during the leafy period. The NH3 emissions from the forest floor during the leafy period were possibly due to the decomposition of leaf litter with increased air temperature. The decrease in leaf area index might induced the increase in NH3 concentration and emission. NH3 emission during the leafless period was also possibly dependent on the state of the deposition surface, apart from air temperature, relative humidity, and leaf area index. Graphical Abstract
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- 2024
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44. High‐resolution atmospheric CO2 concentration data simulated in WRF‐Chem over East Asia for 10 years
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Min‐Gyung Seo, Hyun Mee Kim, and Dae‐Hui Kim
- Subjects
changes and growth rate of atmospheric CO2 concentrations ,East Asia ,high‐resolution atmospheric CO2 concentration data for 10 years ,surface and satellite CO2 observations ,WRF‐Chem ,Meteorology. Climatology ,QC851-999 ,Geology ,QE1-996.5 - Abstract
Abstract In this study, high‐resolution CO2 concentration data were generated for East Asia to analyse long‐term changes in atmospheric CO2 concentrations, as East Asia is an important region for understanding the global carbon cycle. Using the Weather Research and Forecasting model coupled with Chemistry (WRF‐Chem), atmospheric CO2 concentrations were simulated in East Asia at a resolution of 9 km for a period of 10 years (2009–2018). The generated CO2 concentration data include CO2 concentrations, biogenic CO2 concentrations, anthropogenic CO2 concentrations, oceanic CO2 concentrations, biospheric CO2 uptake, biospheric CO2 release and meteorological variables at 3‐h intervals. The simulated high‐resolution CO2 concentrations, biogenic CO2 concentrations and anthropogenic CO2 concentrations are stored in NetCDF‐4 (Network Common Data Form, version 4) format and are available for download at https://doi.org/10.7910/DVN/PJTBF3. The simulated annual mean surface CO2 concentrations in East Asia were 391.027 ppm in 2009 and 412.949 ppm in 2018, indicating an increase of 21.922 ppm over the 10‐year period with appropriate seasonal variabilities. The monthly mean CO2 concentrations in East Asia were verified using surface CO2 observations and satellite column‐averaged CO2 mole fraction (XCO2) from Orbiting Carbon Observatory 2 (OCO‐2). Based on surface CO2 observations and OCO‐2 XCO2 concentrations, the average root‐mean‐square error (RMSE) of the simulated CO2 concentrations in WRF‐Chem was 2.474 and 0.374 ppm, respectively, which is smaller than the average RMSE of the low‐resolution CarbonTracker 2019B (CT2019B) simulation. Therefore, the simulated high‐resolution atmospheric CO2 concentrations in East Asia in WRF‐Chem over 10 years are reliable data that resemble the observed values and could be highly valuable in understanding the carbon cycle in East Asia.
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- 2024
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45. The disease burden of bladder cancer and its attributable risk factors in five Eastern Asian countries, 1990–2019: a population-based comparative study
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Li-Sha Luo, Hang-Hang Luan, Ping Zhang, Jun-Feng Jiang, Xian-Tao Zeng, Jiao Huang, and Ying-Hui Jin
- Subjects
Bladder cancer ,Comparative study ,Disability-adjusted life years ,East Asia ,Smoking ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Backgrounds The study aimed to estimate bladder cancer burden and its attributable risk factors in China, Japan, South Korea, North Korea and Mongolia from 1990 to 2019, to discuss the potential causes of the disparities. Methods Data were obtained from the Global Burden of Disease Study 2019. The annual percent change (APC) and average annual percent change (AAPC) were calculated by Joinpoint analysis, and the independent age, period and cohort effects were estimated by age-period-cohort analysis. Results In 2019, the highest incidence (7.70 per 100,000) and prevalence (51.09 per 100,000) rates of bladder cancer were in Japan, while the highest mortality (2.31 per 100,000) and DALY rates (41.88 per 100,000) were in South Korea and China, respectively. From 1990 to 2019, the age-standardized incidence and prevalence rates increased in China, Japan and South Korea (AAPC > 0) and decreased in Mongolia (AAPC
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- 2024
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46. Electrical conductivity of mantle minerals beneath East Asia revealed by geomagnetic observatory data
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Yuyan Zhang, Mina Ma, Yujia Hu, Yiliang Han, and Yanhui Zhang
- Subjects
Electrical conductivity ,East Asia ,1D inversion ,Mantle transition zone ,Geomagnetic depth sounding ,Geography. Anthropology. Recreation ,Geology ,QE1-996.5 - Abstract
Abstract The electrical conductivity of the earth’s mantle can provide important information about geodynamic phenomena. East Asia is associated with complex tectonics and geodynamic processes. Hence, it is necessary to better understand the deep structure beneath East Asia. In this study, geomagnetic data obtained from East Asian observatories are employed to image the conductivity structure of the mantle at depths ranging from 410 to 900 km. First, the data are processed using the modified bounded influence remote reference processing (BIRRP) method and the ratio method is used to correct for the ocean effect. Thereafter, the stable C-response curves at the 27 observatories are estimated, and 1D electrical conductivity models for these observatories are established using the L-BFGS method. The conductivity-depth profiles reveal a heterogeneous distribution of the electrical conductivity beneath East Asia. The mantle transition zone (MTZ) beneath East China and Japan is found to be more conductive, whereas the MTZ beneath central and southern regions of China is more resistive. In East China, the dehydration of the stagnant Pacific slab may lead to an increase in the conductivity of the mantle minerals. There is also the possibility of upwelling of the thermal material from the lower mantle beneath the Japanese Island arc. In Northwest China, there exists a large high-conductive body beneath the Tarim area, which could indicate an upwelling of the Tarim mantle plume. Our results provide insights into the deep structure of the earth at the mantle scale.
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- 2024
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47. The price of knowing: Musquiqui Chihying
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Lentchner, Anna
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- 2024
48. From Foes to Friends: China and the United States in Laos' Foreign Policy
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Sayalath, Soulatha
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United States. Congress -- International economic relations ,Political parties -- Vietnam -- China -- East Asia -- Laos -- Southeast Asia -- Cambodia -- Thailand ,Foreign policy ,Communism -- Thailand -- East Asia -- Southeast Asia -- Cambodia -- China -- Vietnam -- Laos ,Security management ,Political science ,Regional focus/area studies - Abstract
Domestic politics has shaped the foreign policy of Laos (formally the Lao Peoples' Democratic Republic, or LPDR) since the 1970s, specifically its relations with China and the United States. During the 1980s, the communist government of the Lao People's Revolutionary Party (LPRP) feared that China and the United States were supporting counter-revolutionary resistance groups, prompting Vientiane to adopt closer relations with Beijing and Washington to ensure its own internal security by motivating them to cut off their support for anti-LPRP groups. As the Soviet Union reduced economic aid to Laos in the latter stages of the Cold War, the LPRP adopted market-based reforms in 1986 to generate closer security and economic cooperation with China and the United States and to grow its economy. Domestic concerns of regime survival and performance legitimacy remain key drivers of Laos' foreign policy. Keywords: Laos, domestic politics, legitimacy, regime survival, China, United States., The existing literature on foreign policy decision-making in Laos (formally the Lao People's Democratic Republic, or LPDR) pays little attention to the role of regime survival or the communist government's [...]
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- 2024
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49. Concepts before Measurement: A Rejoinder to Ryan Murphy on the Developmental State
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Cheang, Bryan
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Protectionism ,Economics ,Political science ,Social sciences - Abstract
Ryan Murphy, who is a coauthor of the Economic Freedom of the World (EFW) index, through the use of statistical and quantitative evidence, insists that Singapore does not exhibit a [...]
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- 2024
50. Exploring East Asia's Successful Early-Stage Covid-19 Response: An Empirical Investigation
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Chung, Kee Hoon, Jung, Haeil, and Jung, Miyeun
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Epidemics -- Control -- East Asia ,Dictatorship -- Influence ,Bureaucracy -- Influence - Abstract
This study examines whether a degree of autocracy and high quality of bureaucracy--two mechanisms often discussed in the context of Covid-19 responses--provide a meaningful explanation for East Asia's relative success compared to the rest of the world at the beginning of the Covid pandemic. Our multiple regression analysis for 111 countries supports our expectation, as East Asia as a region is significantly and negatively associated with confirmed Covid-19 cases and deaths compared to the rest of the world, and its interaction with the quality of bureaucracy further contributes to the negative association. In sum, this research highlights the important role of East Asia's regional characteristics in pandemic responses. Keywords: East Asia; autocracy; quality of bureaucracy; democracy; Covid-19 responses, Introduction Although most nations struggled to contain Covid-19 early in the pandemic, East Asian countries seemed to have been more successful than others. Research on East Asia and Covid-19 suggests [...]
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- 2024
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