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5. Outcome of sleepiness and fatigue scores in obstructive sleep apnea syndrome patients with and without restless legs syndrome after nasal CPAP

Author

Rodrigues, Raimundo Nonato Delgado, Rodrigues, Aída Alexandra Alvim de Abreu e Silva, Pratesi, Riccardo, Gomes, Marília Miranda Fortes, Vasconcelos, Ana Maria Nogales, Erhardt, Christine, and Krieger, Jean

Subjects
SAOS, RLS, escala de sonolência de Epworth, OSAS, ESS, fadiga, fatigue, sonolência, sleepiness, Pichot, síndrome das pernas inquietas
Abstract

BACKGROUND & PURPOSE: The association of obstructive sleep apnea syndrome (OSAS) and restless legs syndrome (RLS) has been reported in the literature for many years. Both conditions may be responsible for fatigue and somnolence complaints secondary to nocturnal sleep disruption. The primary concern of this study is to evaluate the outcome of fatigue and daytime sleepiness symptoms at baseline and after continuous positive air pressure (CPAP) treatment in OSAS patients with and without RLS. METHOD: A prospective and comparative study between a group of 13 patients with OSAS and a group of 17 patients with OSAS+RLS. Laboratory blood tests and polysomnography were performed at baseline. The Epworth Sleepiness Scale (ESS) and the Pichot’s questionnaire of fatigue/depression (PIC) were applied before and after 3 months of CPAP treatment. Results were compared. RESULTS: No significant differences were found on PSG and laboratory results at baseline. Both groups had similar ESS and PIC scores at baseline (p=0.73 and 0.08, respectively). After n-CPAP, OSAS+RLS patients showed higher ESS and PIC scores (p=0.017 and 0.03, respectively). CONCLUSIONS: Despite a favorable general response, n-CPAP seemed less effective in treating fatigue and sleepiness in the OSAS+RLS group. OBJETIVO: A associação síndrome de apnéia obstrutiva do sono / síndrome de pernas inquietas (SAOS-SPI) tem sido mencionada na literatura há muito. Ambas podem ser responsáveis por queixas de fadiga e sonolência secundárias à fragmentação do sono noturno. O objetivo deste estudo é avaliar a evolução dos sintomas de fadiga e sonolência diurna excessiva antes e após o tratamento com pressão aérea positiva contínua (CPAP) em pacientes portadores de SAOS, com e sem SPI. MÉTODO: Estudo prospectivo e comparativo entre um grupo de 13 pacientes com SAOS e um grupo de 17 com SAOS +SPI. Exames laboratoriais e polissonografia (PSG) foram realizados no início do estudo. A escala de sonolência de Epworth (ESE) e o questionário de fadiga/depressão de Pichot (PIC) foram aplicados antes do tratamento com CPAP e 3 meses após. Os resultados foram comparados. RESULTADOS: No início do estudo não foram encontradas diferenças significativas na avaliação laboratorial e PSG. Ambos os grupos apresentavam inicialmente pontuação semelhante na avaliação da ESE e PIC (p=0,73 e 0,08, respectivamente). Após CPAP, os pacientes SAOS+SPI apresentaram maiores ESE e PIC (p=0,017 e 0,03, respectivamente). CONCLUSÃO: Apesar de resposta inicial favorável em ambos os grupos, o CPAP foi aparentemente menos eficaz na redução das queixas de fadiga e sonolência nos pacientes apnéicos com associação a SPI.

Published
2007

8. Erratum: Narcolepsy is strongly associated with the T-cell receptor alpha locus

Author

Hallmayer, Joachim, primary, Faraco, Juliette, additional, Lin, Ling, additional, Hesselson, Stephanie, additional, Winkelmann, Juliane, additional, Kawashima, Minae, additional, Mayer, Geert, additional, Plazzi, Giuseppe, additional, Nevsimalova, Sona, additional, Bourgin, Patrice, additional, Hong, Sheng Seung-Chul, additional, Honda, Yutaka, additional, Honda, Makoto, additional, Högl, Birgit, additional, Longstreth, William T, additional, Montplaisir, Jacques, additional, Kemlink, David, additional, Einen, Mali, additional, Chen, Justin, additional, Musone, Stacy L, additional, Akana, Matthew, additional, Miyagawa, Taku, additional, Duan, Jubao, additional, Desautels, Alex, additional, Erhardt, Christine, additional, Hesla, Per Egil, additional, Poli, Francesca, additional, Frauscher, Birgit, additional, Jeong, Jong-Hyun, additional, Lee, Sung-Pil, additional, Ton, Thanh G N, additional, Kvale, Mark, additional, Kolesar, Libor, additional, Dobrovolná, Marie, additional, Nepom, Gerald T, additional, Salomon, Dan, additional, Wichmann, H-Erich, additional, Rouleau, Guy A, additional, Gieger, Christian, additional, Levinson, Douglas F, additional, Gejman, Pablo V, additional, Meitinger, Thomas, additional, Young, Terry, additional, Peppard, Paul, additional, Tokunaga, Katsushi, additional, Kwok, Pui-Yan, additional, Risch, Neil, additional, and Mignot, Emmanuel, additional

Published
2009
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9. Narcolepsy is strongly associated with the T-cell receptor alpha locus

Author

Hallmayer, Joachim, primary, Faraco, Juliette, additional, Lin, Ling, additional, Hesselson, Stephanie, additional, Winkelmann, Juliane, additional, Kawashima, Minae, additional, Mayer, Geert, additional, Plazzi, Giuseppe, additional, Nevsimalova, Sona, additional, Bourgin, Patrice, additional, Hong, Seung-Chul, additional, Honda, Yutaka, additional, Honda, Makoto, additional, Högl, Birgit, additional, Longstreth, William T, additional, Montplaisir, Jacques, additional, Kemlink, David, additional, Einen, Mali, additional, Chen, Justin, additional, Musone, Stacy L, additional, Akana, Matthew, additional, Miyagawa, Taku, additional, Duan, Jubao, additional, Desautels, Alex, additional, Erhardt, Christine, additional, Hesla, Per Egil, additional, Poli, Francesca, additional, Frauscher, Birgit, additional, Jeong, Jong-Hyun, additional, Lee, Sung-Pil, additional, Ton, Thanh G N, additional, Kvale, Mark, additional, Kolesar, Libor, additional, Dobrovolná, Marie, additional, Nepom, Gerald T, additional, Salomon, Dan, additional, Wichmann, H-Erich, additional, Rouleau, Guy A, additional, Gieger, Christian, additional, Levinson, Douglas F, additional, Gejman, Pablo V, additional, Meitinger, Thomas, additional, Young, Terry, additional, Peppard, Paul, additional, Tokunaga, Katsushi, additional, Kwok, Pui-Yan, additional, Risch, Neil, additional, and Mignot, Emmanuel, additional

Published
2009
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11. OUTCOME OF SLEEPINESS AND FATIGUE SCORES IN OBSTRUCTIVE SLEEP APNEA SYNDROME PATIENTS WITH AND WITHOUT RESTLESS LEGS SYNDROME AFTER NASAL CPAP.

Author

Delgado Rodrigues, Raimundo Nonato, Alvim De Abreu E Silva Rodrigues, Aída Alexandra, Pratesi, Riccardo, Fortes Gomes, Marília Miranda, Nogales Vasconcelos, Ana Maria, Erhardt, Christine, and Krieger, Jean

Abstract

Copyright of Arquivos de Neuro-Psiquiatria is the property of Thieme Medical Publishing Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2007
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12. Building Specialized Nursing Practice Capacity in Bangladesh: An Educational Program to Prepare Nurses to Care for Oncology and Bone Marrow Transplant Patients in Dhaka, Bangladesh.

Author

Barron AM, Moran J, Nina SS, Harlow J, Gyawali M, Hossain F, Brezina M, Callahan C, Curran J, Danielson C, Fitzgerald E, Foster J, Erhardt E, Shaughnessy C, Yeh AC, and Dey BR

Subjects
Bangladesh epidemiology, Bone Marrow Transplantation, Education, Nursing, Humans, Medical Oncology methods, Medical Oncology standards, Medical Oncology trends, National Health Programs, Nurses, Patient Care, Public Health Surveillance, Capacity Building, Medical Oncology statistics & numerical data, Nursing Care methods, Nursing Care standards, Nursing Care statistics & numerical data, Nursing Care trends
Abstract

In 2012, the Minister of Health and other leaders in the Bangladesh government approached Massachusetts General Hospital to establish the country's first bone marrow transplant program at Dhaka Medical College Hospital to serve the needs of the people of Bangladesh. Stated goals of this collaboration included a broad focus on the care of oncology patients with a specific emphasis on care of patients with hematologic malignancies and of women with gynecologic cancers. The purpose of this article is to describe the international nursing collaboration between Massachusetts General Hospital, Simmons College, the AK Khan Healthcare Trust in Dhaka, and Dhaka Medical College Hospital that was established to share nursing knowledge and to build specialized professional nursing capacities to deliver high-quality cancer care in the public sector. Over the past 3 years, through the educational programs that have been developed within this collaboration-the Enhanced Specialized Nurse Training Program-the Bangladeshi nurses have received continuing professional development based on Western standards of nursing and have been offering nursing care to patients who have undergone chemotherapy and bone marrow transplantation. The challenges, opportunities, and outcomes of this international collaboration have been highly rewarding and mutually beneficial.

Published
2018
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