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Arı poleni, çiçek poleni ve nektar ile arı tükürük maddelerinin karmaşık bir karışımıdır. Karbonhidratlar, proteinler, lipidler, vitaminler ve fenolik bileşikler gibi birçok biyolojik olarak aktif maddenin zengin bir kaynağı olarak ünlüdür. Bileşimi, botanik kökenlere ve edafoklimatik koşullara göre büyük ölçüde değişir. Bu çalışmada, Cezayir'in kuzeydoğusunda bulunan farklı arılıklardan toplanan insan tüketimine yönelik sekiz arı poleninin botanik orijini, toplam fenolik içerikleri, toplam flavonoid içerikleri, toplam flavonol içerikleri ve in vivo antiinflamatuar aktiviteleri belirlendi ve karşılaştırıldı. Tüm örnekler, 22 botanik familyaya ait kırk polen türünün tanımlanmasıyla heterofloral olarak saptandı. Toplam fenolik içerik 752,94 ± 17,78 ile 12247,06 ± 40,04 mg GAE/ 100 arasında değişirken, toplam flavonoid içeriği 2680,55 ± 12,02 ila 8506,94 ± 15,56 mg QE/ 100g arasında değişmekte ve toplam flavonol içeriği 4978,87 ± 33,39 ile arasında değişmektedir. 7903,75 ± 24,39 mg QE/ 100g. Sonuçlar etanolik ekstraktların büyük kısmının iyi bir anti-inflamatuar aktiviteye sahip olduğunu göstermektedir. Sonuç olarak, yukarıda bahsedilen tüm heterofloral arı poleni örnekleri, potansiyel bir anti-inflamatuar aktiviteye sahip zengin bir polifenol kaynağı olabilir., Bee pollen is multiplex blend of floral pollen and nectar agglutinated by bee salivary substances. It is famously known for being high in proteins, carbs, lipids, vitamins, and phenolic compounds, among other physiologically dynamic components. Its composition fluctuates incredibly agreeing to both botanical origins and edaphoclimatic conditions. In this work, the botanical origin, the phenolic components and the anti-inflammatory activity in vivo of eight bee pollens intended for human consumption were taken from distinctive apiaries in Algeria’s northeast, were determined and compared. All samples were detected heterofloral based on the identification of forty pollen types belonging to 22 botanical families. Total phenolic contents varied between 752.94 ± 17.78 and 12247.06 ± 40.04 mg GAE/ 100g, while the total flavonoid contents ranged from 2680.55 ± 12.02 to 8506.94 ± 15.56 mg QE/ 100g, and the total flavonol contents were in the interval between 4978.87 ± 33.39 and 7903.75 ± 24.39 mg QE/ 100g. The obtained results showed that the bulk of the ethanolic extracts had a good anti-inflammatory activity. As a conclusion, all the aforementioned heterofloral bee pollen samples could significantly be a wealthy source of polyphenols with a potential anti-inflammatory activity.

The aim of this study is to investigate the antioxidant and protective effect of an aqueous extract from Urtica dioica on liver injuries, induced by one of the most potent dietary carcinogenic agents N- Nitroso methyl urea (NMU). Firstly, the free radical scavenging activity of U. dioica extract was assessed by measuring its capability to scavenge the radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). Liver injury was induced in mice by intraperitoneal injection of NMU (50 mg/kg) while the aqueous extract of U. dioica was administered orally to the experimental animals. Haematoxylin/ Eosin based histology was performed to evaluate the histological changes in the liver. The result suggest that U. dioica extract contains high content of polyphenols and able to reduce DPPH radical. Furthermore, NMU treatment induces steatosis in mice liver, which is accompanied by inflammatory cell infiltration. Data show also that U. dioica extract can protect mice liver from NMU induced damage. These findings proved that U. dioica extract has an antioxidant activity and hepatoprotective effect against NMU induced injury. Key words: N-nitrosomethylurea, Urtica dioica, antioxidant, liver.