104 results on '"EKİM, Okan"'
Search Results
2. Ocular pharmacokinetics and toxicity of nanoparticular acetazolamide: In vivo distribution and safety of PHBV-ACZ nanoparticle
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Erdal, Ebru, Bakici, Caner, Arslan, Aslıhan, Batur, Barış, Yaman, Mehmet Emrah, Alçığır, Mehmet Eray, Akyol, Mesut, Ekim, Okan, Salih, Bekir, and Uğurlu, Nagihan
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- 2023
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3. Exploring the morphology of the glandula uropygialis in Denizli rooster: 3 tesla MRI and histological investigation
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Batur, Barış, primary, Kutlu, Tuncer, additional, Bakıcı, Caner, additional, Altunay, Hikmet, additional, Yücel Tenekeci, Gözde, additional, Ekim, Okan, additional, and Oto, Çağdaş, additional
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- 2024
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4. Small Warriors of Nature: Novel Red Emissive Chlorophyllin Carbon Dots Harnessing Fenton‐Fueled Ferroptosis for In Vitro and In Vivo Cancer Treatment
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Kirbas Cilingir, Emel, primary, Besbinar, Omur, additional, Giro, Linda, additional, Bartoli, Mattia, additional, Hueso, Jose L., additional, Mintz, Keenan J., additional, Aydogan, Yagmur, additional, Garber, Jordan M., additional, Turktas, Mine, additional, Ekim, Okan, additional, Ceylan, Ahmet, additional, Unal, Mehmet Altay, additional, Ensoy, Mine, additional, Arı, Fikret, additional, Ozgenç Çinar, Ozge, additional, Ozturk, Berfin Ilayda, additional, Gokce, Cemile, additional, Cansaran‐Duman, Demet, additional, Braun, Markus, additional, Wachtveitl, Josef, additional, Santamaria, Jesus, additional, Delogu, Lucia Gemma, additional, Tagliaferro, Alberto, additional, Yilmazer, Açelya, additional, and Leblanc, Roger M., additional
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- 2024
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5. The Efficiency of 3D-Printed Dog Brain Ventricular Models from 3 Tesla (3T) Magnetic Resonance Imaging (MRI) for Neuroanatomy Education.
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Ekim, Okan, Bakici, Caner, Akçay, Aytaç, Algin, Oktay, and Oto, Cagdas
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THREE-dimensional imaging , *CEREBRAL ventricles , *MAGNETIC resonance imaging , *VETERINARY medicine education , *MAGNETIC resonance - Abstract
Neuroanatomy is widely regarded as one of the most complex subjects in veterinary education and clinical practice. Understanding the brain ventricles in particular can be quite challenging for learners. In addition to classical methods, three-dimensional (3D) printed models can provide an efficient learning process. This study aimed to assess the effectiveness of 3D-printed models (3DPM) depicting the dog brain ventricular system as educational tools in neurology and neuroanatomy. Additionally, it outlines the process of creating these models, from imaging specimens with a 3 Tesla magnetic resonance (MR) to 3D printing. MR imaging was performed on four mesocephalic dogs. The semi-automatic technique was performed on MR images to generate a 3D reconstruction of the brain ventricles. 3D digital images were used to create 3DPM with an FDM printer. An evaluation survey for learners was also conducted to evaluate the efficiency of 3DPM for neuroanatomy education. The ventricular system and associated anatomical structures were easily identified on MR images. A detailed 3D model of the ventricular system was created by this method. It was determined that 3DPM was easily handled, quickly reproducible, cost-efficient, and storable. Besides, a significant number of students stated that the use of 3DPM is necessary and will be more useful in learning neuroanatomy. This technique could help not only education partners like lecturers and learners but also clinicians like radiologists and surgeons to understand canine ventricular anatomy better. [ABSTRACT FROM AUTHOR]
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- 2024
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6. The use of plastinated specimens for hybrid education of Veterinary Anatomy
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EKİM, Okan, primary, BAKICI, Caner, additional, BATUR, Barış, additional, and TUNALI, Selçuk, additional
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- 2023
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7. Differentiation of Anatomic Entities in the Dog Stifle Joint Following S10B Plastination: Comparative Colorimetric and Radiological Investigations
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Bakici Caner, Akgun Remzi Orkun, Ekim Okan, Insal Burcu, Kaya Ufuk, Bilgili Hasan, Bumin Ali, and Cakir Ahmet
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colorimetric analysis ,computed tomography ,cross-sectional anatomy ,knee ,three-dimensional reconstruction ,Veterinary medicine ,SF600-1100 - Abstract
The knee joint is not only the most important and complex structure to present during anatomy lectures, but also a significant region for radiologists and orthopedicians. The objectives of this paper are: 1) to evaluate the efficacy of plastinated specimens by measuring colorimetric differentiation and 2) to compare the anatomical structures of the images obtained from computed tomography (CT) and silicone plastination cross-sections and perform three-dimensional (3D) reconstructed models of the specimens. A total of 16 knee joints selected from the 10% formalin fixed/dissected group (n=6), non-fixed/dissected group (n=6) and non-dissected whole knee joint group (n=4) were scanned by CT and plastinated by using the S10B silicone technique. The color changes of the structures were quantitatively determined with the colorimeter device. Plastinated whole knee joints were cut transversally with a band saw and compared with CT images. Finally, 3D reconstruction of the knee joints was performed from CT images with the 3D reconstruction program. There were statistically significant differences between the fixed and non-fixed groups in terms of color changes (p
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- 2019
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8. The use of plastinated specimens for hybrid education of Veterinary Anatomy.
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EKİM, Okan, BAKICI, Caner, BATUR, Barış, and TUNALI, Selçuk
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VETERINARY anatomy , *VETERINARY medicine education , *BLENDED learning , *COVID-19 pandemic , *ACRYLIC paint - Abstract
With the official announcement of the new type of coronavirus-induced COVID-19 outbreak as a global pandemic, an extraordinary situation that no one has ever encountered has started. Just as life was about to return to normal in Türkiye, two devastating earthquakes, centered in Kahramanmaraş, affected ten different cities. Many global and national developments in various fields, which are expected to happen in the distant future, were completed within 3 years. One of these fields was undoubtedly education. Hybrid learning is seen as a trending educational approach combining face-to-face and online learning. Plastinated specimens come to the forefront for hybrid education with various advantageous features. They are not only non-toxic, dry, odorless materials, but also can simulate the natural anatomic appearance in detailed manner. With the help of new-generation acrylic paints and dyes which can penetrate into tissues, plastinates offer a unique natural look rather impressive than any other techniques. Due to the features mentioned above, plastinates are also convenient materials for handling, transportation or storage. These issues will be discussed in our article in terms of compatibility with hybrid learning. The aim of this article is to give ideas and make suggestions about how plastinates, which have been used efficiently in anatomy practices and professional training, can be used in hybrid veterinary anatomy education. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Near-infrared light transillumination for occlusal caries detection in dog teeth: A comparative study.
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KOLSUZ, Mehmet Eray, EKİM, Okan, IRMAK, Özgür, EVLİ, Cengiz, BAKICI, Caner, and DEMİREL, Gülbike
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NEAR infrared radiation , *DENTAL caries , *DETECTOR dogs , *TRANSILLUMINATION , *MOLARS , *DOG walking - Abstract
The aim of this study is to compare the effectiveness of visual, radiologic, and near-infrared light transillumination caries detection methods on caries of dog teeth in-vitro. A total of 237 dog molar teeth were evaluated with three different methods; visio-tactile examination with a probe, radiographic assessment, and NIR-LT. Each tooth was evaluated with all of the methods; the absence or presence of occlusal caries was scored as either 0, caries not present, or 1, caries present. All caries detection methods yielded the same outcomes for each tooth. Among all caries detection methods positive Spearman's rho value (1=1) indicated that there was a strong positive correlation between the caries detection methods. Since NIR-LT is such a comfortable and easy caries diagnosis method, it can be used without sedation, especially in calm dogs. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Magnetic resonance imaging, computed tomography, and gross anatomy of forelimb joints in New Zealand rabbit (Oryctolagus cuniculus L.)
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Akgun, Remzi Orkun, primary, Orhan, Ismail Onder, additional, Ekim, Okan, additional, and Bumin, Ali, additional
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- 2023
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11. Clindamycin phosphate and bone morphogenetic protein-7 loaded combined nanoparticle-graft and nanoparticle-film formulations for alveolar bone regeneration – An in vitro and in vivo evaluation
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Ilhan, Miray, primary, Kilicarslan, Muge, additional, Alcigir, Mehmet Eray, additional, Bagis, Nilsun, additional, Ekim, Okan, additional, and Orhan, Kaan, additional
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- 2023
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12. Silicone plastination of spinal cord of cat: as an alternative specimen for neuroanatomy education
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EKİM, Okan, YUNUS, Hasen Awel, BAKICI, Caner, and BATUR, Barış
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Veterinary ,Cat ,Neuroanatomy ,Silicone Plastination ,Spinal Cord ,Veteriner Hekimlik - Abstract
Plastination is a technique that aims to preserve biological materials for education, training, and research. Plastinated models increase knowledge and skill, make students easily understand the complex anatomical parts of the central nervous system, meanwhile can reduce the use of animals in research and education. The study aimed to produce a silicone plastinated model of the spinal cord of a cat for practical teaching of neuroanatomy. The spinal cord of a stray cat that died of natural causes was plastinated using silicone plastination method. The cervical spinal nerves (1-8) and brachial plexus were demonstrated. The thoracic region of the spinal cord was also well preserved, but the demonstration of thoracic spinal nerves became very difficult because of too much thinness of the nerves. The lumbosacral plexus was preserved well. In this region cranial iliohypogastric nerve, caudal iliohypogastric nerve, ilioinguinal nerve, femoral nerve, gluteal nerve, ischiadic nerve, obturator nerve, pudendal nerve and cauda equina were visible. The spinal cord of cats prepared by silicone plastination methods can be used as an alternative sample to formalin preserved specimens.
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- 2022
13. What Makes a Museum Interactive? An Overview of Education Activities in the Ankara Veterinary Anatomy Museum.
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Ekim, Okan and Güneröz, Ceren
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Museums operate and communicate ethically, professionally, and with the participation of their constituents, offering varied experiences for edutaintment and knowledge sharing. Today’s museums ensure relevance in national and universal development by considering, first and foremost, educational functions. Museums work in harmony with people in both neighboring areas and farther surroundings to create a participatory system under the guidance of cultural, environmental, ecological, and economic indicators and to develop heritage. The Ankara Veterinary Anatomy Museum (AVAM), provides regular education and outreach activities. Preparations of the anatomical specimens for education and exhibition purposes began with the establishment of the Chair of Anatomy. AVAM aims to be a scientific reference environment for postgraduate students, and researchers, but also a space for the public. This article evaluates the AVAM’s major educational programs and includes the opinions and suggestions of undergraduate students working as educators in the museum about the validity of these programs. [ABSTRACT FROM AUTHOR]
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- 2023
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14. Anatomical evaluation and preparation procedure of a cross-sectioned kidney plastination of a thoroughbred horse with local polyester resin.
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BAKICI, Caner, YUNUS, Hasen Awel, BATUR, Barış, EKİM, Okan, and TUNALI, Selçuk
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THOROUGHBRED horse ,ANATOMICAL specimens ,KIDNEYS ,POLYESTERS ,ULTRAVIOLET radiation ,FORMALDEHYDE ,POLYESTER fibers - Abstract
This study aimed to develop a protocol for the thin section plastination of the kidney with local polyester resin and examine the anatomical details of this specimen. The sample was fixed with 10% formalin fixation solution and then sectioned into 3 mm slices. The four stages of the polyester plastination technique were used. Firstly, the samples were kept in 99.5% acetone baths at -25°C for the dehydration. After this process, the sections were placed in polyester resin and the impregnation process was started at room temperature (20°C) under vacuum. Following the forced impregnation, the curing chambers were constructed and the curing process was continued under ultraviolet light. The data of each applied stage were recorded carefully and the protocol for polyester plastination of kidney sections was successfully established. The specimens were observed from a different point of view with a thin cross-sectional appearance. The anatomical morphology and the structures of the sections of the kidney such as renal parenchyma and circulatory components were preserved well. The final products could be used as educational samples for cross-sectional anatomical training of kidneys. [ABSTRACT FROM AUTHOR]
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- 2023
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15. Comparative Evaluation of Anatomic Structures in Regio manus and Regio pedis on Computed Tomography Images and Plastinated Cross-Sections of Horse/ Evaluacion Comparativa de Estructuras Anatomicas en Regio Manus y 1 en Imagenes de Tomografia Computarizada y Cortes Transversales Plastinados de Caballos
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Bakici, Caner, Akgun, Remzi Orkun, Ekim, Okan, Orhan, Ismail Onder, and Bumin, Ali
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- 2019
16. Evaluacion Seccional de Estructuras Anatomicas de la Cavidad Toracica en Gato (Felis catus) con Imagenes de Tomografia Computada y Metodos de Plastinacion de Silicona
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Orkun Akgün, Remzi, Bakici, Caner, Ekim, Okan, Bumin, Ali, and Önder Orhan, Ismail
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- 2018
17. Near-infrared light transillumination for occlusal caries detection in dog teeth: A comparative study
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KOLSUZ, Mehmet Eray, primary, EKİM, Okan, additional, IRMAK, Özgür, additional, EVLİ, Cengiz, additional, BAKICI, Caner, additional, and DEMİREL, Gülbike, additional
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- 2022
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18. Safkan Bir Atın Lokal Polyester Reçine ile Kesitli Böbrek Plastinasyonunun Anatomik Değerlendirmesi ve Hazırlama Prosedürü
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BAKICI, Caner, primary, YUNUS, Hasen Awel, additional, BATUR, Barış, additional, EKİM, Okan, additional, and TUNALI, Selçuk, additional
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- 2022
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19. From toxic cadavers to biosafe specimens: a brief history of plastination in veterinary anatomy
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YUNUS, Hasen Awel, primary, EKİM, Okan, additional, BAKICI, Caner, additional, BATUR, Barış, additional, and ÇAKIR, Ahmet, additional
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- 2022
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20. Anatomical study of the scleral ring and eyeball of the long‐eared owl (Asio otus) with anatomical methods and diagnostic imaging techniques
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Zehtabvar, Omid, primary, Masoudifard, Majid, additional, Ekim, Okan, additional, Ghorbani, Faezeh, additional, Davudypoor, Somaye, additional, Memarian, Iman, additional, and Zarghami Dastjerdi, Paniz, additional
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- 2022
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21. Morphological pattern of the pes tendons in Bennett's Wallaby ( Macropus rufogriseus )
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Yunus, Hasen Awel, primary, Ekim, Okan, additional, Bakıcı, Caner, additional, Bakıcı, Merve, additional, and Batur, Barış, additional
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- 2022
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22. Accuracy and Reliability of Measurements Obtained from 3-Dimensional Rabbit Mandible Model: A Micro-Computed Tomography Study
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Orkun Akgun Remzi, Kaya Ufuk, Ekim Okan, Özlem Küçük Nuriye, and Bakıcı Caner
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Molar ,Veterinary medicine ,rabbit ,Bone tissue ,01 natural sciences ,Mental foramen ,mandible ,03 medical and health sciences ,0302 clinical medicine ,Incisor ,stomatognathic system ,SF600-1100 ,medicine ,Foramen ,Orthodontics ,General Veterinary ,three-dimensional reconstruction ,business.industry ,Mandible ,030206 dentistry ,micro computed tomography ,0104 chemical sciences ,010404 medicinal & biomolecular chemistry ,medicine.anatomical_structure ,Diastema ,Calipers ,business ,morphometry - Abstract
The aim of this study was to evaluate the mandibular morphometric measurements of male and female rabbits using three-dimensional digital model and real bone measurements. Ten (5 female, 5 male) rabbits with no bone deformities were used in the study. Three-dimensional models were produced from two-dimensional microcomputed tomography images of the rabbit’s mandible. Biometric data were obtained by using the same measuring points over both three-dimensional models and real bone samples. There was only a significant main effect of gender for the greatest length of the mandible, length from aboral border of the alveolus of third molar teeth to infradentale, length of the diastema, height of the vertical ramus (measured in projection), distance from the incisor to the oral border of mental foramen, distance from aboral border of mental foramen to caudal border of mandible, distance between retroalveolar foramen and caudal border of mandible. For these measurements, calculated data for females are significantly higher than the males (p
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- 2019
23. Computer-aided three dimensional morphometric measurements of cervical vertebrae variations compared with manual measurements in throughbred horses
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Bakıcı, Caner, Batur, Barış, Akgün, Remzi Orkun, Kaya, Ufuk, Ekim, Okan, Oto, Çağdaş, Hazıroğlu, Reşide Merih, and Başka Kurum
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3D measurement ,Anatomical variation ,3B anatomi ,bilgisayarlı tomografi ,3B ölçüm ,computed tomography ,Anatomik varyasyon ,at ,3D anatomy ,horse - Abstract
Aim: The aim of this study was to create three-dimensional (3D) models of each cervical vertebra with computed tomography (CT) images; to determine the morphometric parameters of each cervical vertebra with manual and digital measurement methods; to compare the accuracy between the two methods. Materials and Methods: The last five cervical vertebrae of four male thoroughbred horses were used for morphometric analyses. All vertebrae were scanned with 256-multidetector CT device. 3D reconstructed models were acquired with 3D slicer software. Twenty-three morphometric parameters were calculated on 3D models and manually by using a digital caliper. Results: Measurement methods*Cervical vertebra interaction term was found statistically significant for height of vertebra, external and internal width of the cranial articular process, width of the vertebral fossa, height of transverse foramen, height of cranial and caudal vertebral notch, and width of the pedicle (p, Amaç: Çalışmada, bilgisayarlı tomografi (BT) görüntüleri ile her bir servikal omurun üç boyutlu (3B) modellerini oluşturmak; manuel ve dijital ölçüm yöntemleri ile her servikal vertebranın morfometrik parametrelerini belirlemek ve iki yöntem arasındaki doğruluğu karşılaştırmak amaçlanmıştır. Gereç ve Yöntem: Morfometrik analizler için dört erkek safkan atın son beş boyun omurları kullanıldı. Tüm omurlar 256 multidetektörlü BT cihazı ile tarandı. 3D Slicer yazılımı ile 3B rekonstrüksiyon modeller elde edildi. Yirmi üç morfometrik parametre, 3B modeller ve dijital kumpas kullanılarak manuel olarak hesaplandı. Bulgular: Ölçüm yöntemleri*servikal omur etkileşim terimi, omur yüksekliği, processus articularis cranialis’in dış ve iç genişliği, fossa vertebralis’in genişliği, foramen transversalis’in yüksekliği, incisura vertebralis’lerin yüksekliği ve pedikül genişliği için istatistiksel olarak anlamlı bulundu (p
- Published
- 2021
24. Hayvanlara Yönelik Davranış Ölçeğinin Geliştirilmesi
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AYSU, Burçin, primary, ARAL, Neriman, additional, ARAL, Oğulcan, additional, GÜRSOY, Figen, additional, EKİM, Okan, additional, and KADAN, Gül, additional
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- 2021
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25. Yeni Zelanda Tavşanı’ında ön bacak eklemlerinin üç boyutlu kemik modellenmesi: Mikro Bilgisayarlı Tomografi çalışması
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AKGÜN, Remzi Orkun, ORHAN, İsmail Önder, and EKİM, Okan
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Veterinary ,Veteriner Hekimlik ,Forelimb joints,laboratory rabbit,micro-computed tomography,morphometry,three-dimensional reconstruction ,Laboratuvar tavşanı,mikro bilgisayarlı tomografi,morfometri,ön bacak eklemleri,üç boyutlu rekonstrüksiyon - Abstract
In this study, it was aimed to obtain 3-dimensional (3D) digital and printed models of healthy forelimb joints using micro-computed tomography (µCT) technique in New Zealand Rabbit, which is frequently preferred in experimental orthopedic studies. Moreover, it was aimed to provide morphometric measurements on the shoulder and elbow joints over 3D digital models. A total of 14 adults (7 female, 7 male) New Zealand Rabbits were used in the study. After imaging the forelimbs with the µCT device, 3D digital and printed models were obtained. Biometric measurements of shoulder and elbow joints were performed over 3D digital models and the data obtained from female and male rabbits were evaluated statistically. The anatomical structure on the 3D joint models was very detailed due to the low section thickness and high detector quality. 3D printed models produced as a result of the 3D printing process were quite durable, odorless, and clean. No anatomical differences were observed between 3D printed models and 3D digital models. In this study, it is thought that the anatomical and morphometric data obtained from laboratory rabbits will contribute to scientists take part both in experimental orthopedic intervention and clinical anatomy education., Bu çalışmada, deneysel ortopedik çalışmalarda sıklıkla tercih edilen Yeni Zelanda Tavşanı’nda sağlıklı ön bacak eklemlerinin mikro bilgisayarlı tomografi (μBT) tekniği ile elde edilen görüntülerinden 3B dijital modellerinin oluşturulması, modeller üzerinde omuz ile dirsek eklemlerine ait morfometrik ölçümlerin sağlanması ve bu modellerden 3B yazıcılar kullanılarak 3B baskı modellerinin üretilmesi amaçlanmıştır. Çalışmada toplamda 14 adet (7 dişi, 7 erkek) erişkin Yeni Zelanda Tavşanı kullanıldı. Ön bacakları μBT cihazı ile görüntülenip görüntülerden 3B dijital ve baskı modelleri elde edildi. 3B dijital modeller üzerinden omuz ile dirsek eklemlerine ait biyometrik ölçümleri gerçekleştirildi. Dişi ve erkek tavşanlara ait elde edilen veriler istatistiki açıdan değerlendirildi. Kesit kalınlığının düşük ve dedektör kalitesinin yüksek olması sebebiyle 3B eklem modellerindeki anatomik yapı oldukça detaylıydı. Üç boyutlu baskılama işlemi sonucunda üretilen 3B baskı modelleri son derece dayanıklı, kokusuz ve temizdi. 3B baskı modelleri ile 3B dijital modeller arasında herhangi bir anatomik farklılık gözlenmedi. Bu çalışmada laboratuvar tavşanlarına ait elde edilen anatomik ve morfometrik verilerin hem deneysel amaçlı ortopedik girişimlerde bulunan hem de klinik anatomi eğitimlerinde rol alan bilim insanlarına katkı sağlayacağı düşünülmektedir.
- Published
- 2020
26. Clinicopathological and immunohistochemical evaluation of lonidamine-entrapped lipid–polymer hybrid nanoparticles in treatment of benign prostatic hyperplasia: An experimental rat model
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Sengel-Turk, Ceyda Tuba, primary, Alcigir, Mehmet Eray, additional, Ekim, Okan, additional, Bakar-Ates, Filiz, additional, and Hascicek, Canan, additional
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- 2020
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27. Three-dimensional bone modeling of forelimb joints in New Zealand Rabbit: A Micro-Computed Tomography study
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AKGÜN, Remzi Orkun, primary, ORHAN, İ̇smail Önder, additional, and EKİM, Okan, additional
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- 2020
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28. Computer-aided three dimensional morphometric measurements of cervical vertebrae variations compared with manual measurements in throughbred horses.
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Bakıcı, Caner, Batur, Barış, Akgün, Remzi Orkun, Kaya, Ufuk, Ekim, Okan, Oto, Çağdaş, and Hazıroğlu, Reşide Merih
- Subjects
CERVICAL vertebrae ,THOROUGHBRED horse ,DIGITAL preservation ,COMPUTED tomography ,ANATOMICAL variation ,HORSES ,THREE-dimensional modeling - Abstract
Copyright of Eurasian Journal of Veterinary Sciences is the property of Eurasian Journal of Veterinary Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2022
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29. Anatomical and Normal 3D CT-Scan Study of the Vertebral Column and the Shell of the European Pond Turtle (Emys orbicularis).
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Zehtabvar, Omid, Vajhi, Ali Reza, Rostami, Amir, Ekim, Okan, Vosoogh-Afkhami, Ali Reza, Davudypoor, Somaye, and Sadri, Sadaf
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SPINE ,EMYS orbicularis ,COMPUTED tomography ,THORACIC vertebrae ,SKELETON - Abstract
Limited information about the skeletal anatomical features of the European pond turtle (Emys orbicularis), one of the species of turtles in Iran, is available. Given that performing clinical examinations as well using imaging techniques require complete anatomical information of the animal, it is essential to study these features in various researches. This study was done to provide complete anatomical information of the vertebrae and different shell parts in European pond turtles, as well as their normal three-dimensional computed tomographic (3D CT)-Scan images in both flexed and extended neck positions. This study was performed on 10 European pond turtles. CT-Scan images were taken from each sample and in the 3D reconstruction of the images, different patterns were used. 8 cervical vertebrae, 10 dorsal vertebrae, 2 sacral vertebrae, and 25 caudal vertebrae were observed in European pond turtles. The cervical vertebrae were highly mobile and there were no cervical ribs. Due to the fusion of the dorsal vertebrae, there were no intervertebral foramina in this section, but very small lateral vertebral foramina were visible. These foramina were formed in the last four dorsal vertebrae at the fusion site and they were larger than the foramina of the cranial vertebrae. According to the results of this study, it can be concluded that the use of diagnostic techniques such as a 3D CT-Scan is very useful in the study of skeletons. The correct direction and position of the bones can be easily determined using this technique. Part of the turtle's ability to contract the neck is due to the special structure of the articular processes of the last two cervical vertebrae and the first dorsal vertebra. One of the most important adaptations in the evolution of the special structure of the seventh and eighth vertebrae of the neck and the way they are articulated. [ABSTRACT FROM AUTHOR]
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- 2022
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30. Photodynamic Therapy: Photocatalytically Active Graphitic Carbon Nitride as an Effective and Safe 2D Material for In Vitro and In Vivo Photodynamic Therapy (Small 10/2020)
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Taheri, Hadiseh, primary, Unal, Mehmet Altay, additional, Sevim, Melike, additional, Gurcan, Cansu, additional, Ekim, Okan, additional, Ceylan, Ahmet, additional, Syrgiannis, Zois, additional, Christoforidis, Konstantinos C., additional, Bosi, Susanna, additional, Ozgenç, Ozge, additional, Gómez, Manuel José, additional, Turktas Erken, Mine, additional, Soydal, Çigdem, additional, Eroğlu, Zafer, additional, Bitirim, Ceylan Verda, additional, Cagin, Umut, additional, Arı, Fikret, additional, Ozen, Asuman, additional, Kuçuk, Ozlem, additional, Delogu, Lucia Gemma, additional, Prato, Maurizio, additional, Metin, Önder, additional, and Yilmazer, Açelya, additional
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- 2020
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31. Photocatalytically Active Graphitic Carbon Nitride as an Effective and Safe 2D Material for In Vitro and In Vivo Photodynamic Therapy
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Taheri, Hadiseh, primary, Unal, Mehmet Altay, additional, Sevim, Melike, additional, Gurcan, Cansu, additional, Ekim, Okan, additional, Ceylan, Ahmet, additional, Syrgiannis, Zois, additional, Christoforidis, Konstantinos C., additional, Bosi, Susanna, additional, Ozgenç, Ozge, additional, Gómez, Manuel José, additional, Turktas Erken, Mine, additional, Soydal, Çigdem, additional, Eroğlu, Zafer, additional, Bitirim, Ceylan Verda, additional, Cagin, Umut, additional, Arı, Fikret, additional, Ozen, Asuman, additional, Kuçuk, Ozlem, additional, Delogu, Lucia Gemma, additional, Prato, Maurizio, additional, Metin, Önder, additional, and Yilmazer, Açelya, additional
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- 2020
- Full Text
- View/download PDF
32. 3 tesla magnetic resonance imaging and multiplanar reconstruction of the brain and its associated structures in sheep
- Author
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BAKICI, Caner, primary, EKİM, Okan, additional, ERGİN, İrem, additional, ALGIN, Oktay, additional, and OTO, Çağdaş, additional
- Published
- 2019
- Full Text
- View/download PDF
33. Three-dimensional bone modeling of forelimb joints in New Zealand Rabbit: A Micro-Computed Tomography study.
- Author
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AKGÜN, Remzi Orkun, ORHAN, İsmail Önder, and EKİM, Okan
- Subjects
THREE-dimensional modeling ,FORELIMB ,LABORATORY rabbits ,ELBOW ,TOMOGRAPHY - Abstract
Copyright of Veterinary Journal of Ankara University / Ankara Universitesi Veteriner Fakultesi Dergisi is the property of Ankara University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
34. S10B Silikon Plastinasyon Yöntemi ile Erişkin İneklerin İç Genital Organlarının Hazırlanması
- Author
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AKGÜN, Remzi Orkun, EKİM, Okan, BAKICI, Caner, İNSAL, Burcu, AYVALI, Muharrem, ORHAN, İsmail Önder, OTO, Çağdaş, and ATANASOFF, Alexander
- Subjects
Health Care Sciences and Services ,Anatomy,Female genital organs,Gynaecology,S10B silicone plastination ,Sağlık Bilimleri ve Hizmetleri ,Anatomi,Dişi genital organlar,Jinekoloji,S10B silikon plastinasyon - Abstract
It is essential to demonstrate organs and their structures practically in anatomy education. Plastination is an anatomical technique that has been used to prepare biological specimens for educational purposes. it is a gradual process by replacement of fluids in biological tissues with reactive polymers such as silicone, epoxy or polyester resin. This study was aimed to plastinate the internal genital organs of adult cows by S10B silicone plastination method. Ten internal genital organs of cows were plastinated to be used in veterinary undergraduate teaching/practices. After dissection and fixation, the specimens were plastinated with S10B plastination method and colour differentiation of the organ parts were measured. The plastination process was completed with dehydration, defatting, impregnation, and gas curing stages, respectively. It was observed that the plastination of specimens with S10B plastination method preserve normal anatomy of genital organs. It was estimated that all parts of uterus became greenish and bluish colour and the value of the brightness of uterus was increased. The tissue shrinkage was reduced considerably when dehydration was carried out in a cold environment. It was concluded that S10B plastination method can be easily used to prepare the specimens of genital organs to be used in veterinary teaching., Anatomi eğitimi sırasında, organları ve bu organların yapılarını uygulamalı olarak göstermek oldukça önemlidir. Plastinasyon, biyolojik örneklerin eğitim amacı ile hazırlanılarak kullanılmakta olan anatomik bir tekniktir. Biyolojik dokulardaki sıvıların silikon, epoksi veya polyester reçine gibi reaktif polimerler ile değiştirilmesi sonucunda gerçekleşen aşamalı bir işlemdir. Bu çalışmada, yetişkin ineklerin iç genital organlarının S10B silikon plastinasyon yöntemi ile plastine edilmesi amaçlanmıştır. Veteriner hekimlik lisans öğretimi ve uygulamalarında kullanılmak üzere 10 adet ineğe ait iç genital organlar plastine edildi. Diseksiyon ve tespit işleminden sonra, örneklere S10B plastinasyon yönteminin diğer önemli aşamaları uygulandı ve organ bölümlerine ait renk değişimleri kantitatif olarak hesaplandı. Plastinasyon işlemleri sırasıyla, dehidrasyon, yağdan arındırma, zorla impregnasyon ve gazla kürleme - sertleştirme aşamaları ile tamamlandı. S10B plastinasyon yöntemi ile plastine edilen örneklerin normal anatomik yapısını koruduğu gözlendi. Uterus'a ait tüm bölümlerin yeşilimsi ve mavimsi bir renk haline geldiği ve uterus'un parlaklık değerinin arttığı belirlendi. Soğuk ortamda dehidrasyon gerçekleştirilmesi ile doku büzüşmesi önemli ölçüde azaldığı belirlendi. Veteriner hekimlik eğitiminde kullanılacak olan genital organ örneklerini hazırlamak için S10B plastinasyon yönteminin kolaylıkla kullanılabileceği sonucuna varıldı.
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- 2019
35. Comparative Evaluation of Anatomic Structures in Regio manus and Regio pedis on Computed Tomography Images and Plastinated Cross-Sections of Horse
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Bakıcı,Caner, Akgün,Remzi Orkun, Ekim,Okan, Orhan,Ismail Onder, and Bumin,Ali
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plastination ,foot ,3D reconstruction ,Computed tomography ,horse - Abstract
SUMMARY: Movement analysis of horses is closely related to the bone, joint and muscle composition. Equine foot is quiet important not only for veterinarians, but also for farmers and horseshoer. In this study, it is aimed to evaluate and compare the anatomical structures of equine foot obtained from computed tomography images and S10B silicone plastinated sections of horse and 3 dimensional images of related structures as well. Four adult horses were used in this study. Computed tomography images were acquired in a proper position for equine feet. Then S10B silicone plastination was performed for the same specimens. Plastinates were sliced into 1 cm sections, corresponding to the computed tomography images. The sections obtained from silicone plastination were found to be compatible with computed tomography images. It was seen that osseous structures and tendons were clearly identified on computed tomography images. It was observed that the shrinkage on the osseous tissues was very limited. It was thought that the proportional differences between the plastinated specimens and computed tomography images were related with the fixation process. The specimens plastinated with S10B silicone polymer was determined to be closer to natural colour when compared to the standard polymers. Therefore it was found to be more useful. It is considered that plastinates can be effectively used in veterinary orthopaedics and radiology trainings as well as in veterinary anatomy education.
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- 2019
36. Comparative Evaluation of Anatomic Structures in Regio manus and Regio pedis on Computed Tomography Images and Plastinated Cross-Sections of Horse
- Author
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Bakıcı, Caner, Akgün, Remzi Orkun, Ekim, Okan, Orhan, Ismail Onder, and Bumin, Ali
- Subjects
plastination ,Tomografía computarizada ,Plastinación ,foot ,Caballo ,Pie ,3D reconstruction ,Reconstrucción 3D ,Computed tomography ,horse - Abstract
SUMMARY: Movement analysis of horses is closely related to the bone, joint and muscle composition. Equine foot is quiet important not only for veterinarians, but also for farmers and horseshoer. In this study, it is aimed to evaluate and compare the anatomical structures of equine foot obtained from computed tomography images and S10B silicone plastinated sections of horse and 3 dimensional images of related structures as well. Four adult horses were used in this study. Computed tomography images were acquired in a proper position for equine feet. Then S10B silicone plastination was performed for the same specimens. Plastinates were sliced into 1 cm sections, corresponding to the computed tomography images. The sections obtained from silicone plastination were found to be compatible with computed tomography images. It was seen that osseous structures and tendons were clearly identified on computed tomography images. It was observed that the shrinkage on the osseous tissues was very limited. It was thought that the proportional differences between the plastinated specimens and computed tomography images were related with the fixation process. The specimens plastinated with S10B silicone polymer was determined to be closer to natural colour when compared to the standard polymers. Therefore it was found to be more useful. It is considered that plastinates can be effectively used in veterinary orthopaedics and radiology trainings as well as in veterinary anatomy education. RESUMEN: El análisis del movimiento de los caballos está estrechamente relacionado con la composición ósea, articular y muscular. El pie equino es muy importante no solo para los veterinarios, sino también para los agricultores y herradores. El objetivo de este trabajo consistió en evaluar y comparar las estructuras anatómicas del pie equino obtenidas a partir de imágenes de tomografía computarizada y secciones plastinadas con silicona S10B y también con imágenes tridimensionales de estructuras relacionadas. Cuatro caballos adultos fueron utilizados en este estudio. Las imágenes de tomografía computarizada se adquirieron en una posición adecuada para los pies equinos. Luego se realizó plastinación con silicona S10B para las mismas muestras. Los plastinados se cortaron en secciones de 1 cm, correspondientes a las imágenes de tomografía computada. Las secciones obtenidas de plastinación con silicona fueron compatibles con las imágenes de tomografía computarizada. Se observó que las estructuras óseas y los tendones estaban claramente identificados en las imágenes de tomografía computarizada. Se observó que la contracción de los tejidos óseos era muy limitada. Se pensó que las diferencias proporcionales entre las muestras plastinadas y las imágenes de tomografía computada estaban relacionadas con el proceso de fijación. Se determinó que las muestras plastinadas con polímero de silicona S10B se presentaron con un color más cercano al natural en comparación con los polímeros estándar. Por lo tanto, se encontró que fue más útil. Se considera que los plastinados se pueden utilizar eficazmente en ortopedia veterinaria y capacitación en radiología, así como en educación en anatomía veterinaria.
- Published
- 2019
37. Sectional Evaluation of Anatomic Structures in Cat (Felis catus) Thoracic Cavity by Computed Tomography Imaging and Silicone Plastination Methods
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Akgün, Remzi Orkun, Bakici, Caner, Ekim, Okan, Bumin, Ali, and Önder-Orhan, Ismail
- Subjects
Tomografía computarizada ,Plastinación ,Anatomía del tórax ,Cat ,Silicona ,Three-dimensional ,Tridimensional ,Computed tomography ,Silicone ,Gato ,Plastination ,Thorax anatomy - Abstract
SUMMARY: It was aimed to determine the anatomical structures in thoracic cavity by computed tomography imaging (CT) and compare the cross sectional images in the same specimens which were plastinated after CT imaging. It was also aimed to obtain 3 dimensional (3D) reconstructions of thoracic anatomical structures. Thoracic organs of 3 adult cats were CT imaged and then plastinated in this study. Specimens were plastinated in the same body position in the CT imaging process. CT images and corresponding plastinated cross sections were compared to each other. Anatomical structures of the thoracic cavity in plastinates were in accordance with CT images. Beside the bony structures, other organs such as esophagus, trachea, heart with related vessels, lungs and thoracic muscles were well defined in CT images and plastinates. Moreover, 3D reconstructed images of anatomical structures of thoracic cavity were acquired well. This study is thought to be beneficial for veterinary surgery and radiology fields as well as veterinary anatomy educations. RESUMEN: El objetivo de este trabajo consistió en determinar las estructuras anatómicas en la cavidad torácica mediante tomografía computarizada (TC) y comparar las imágenes transversales en las mismas muestras, que fueron plastinadas después de la TC. También se pretendía obtener reconstrucciones tridimensionales (3D) de estructuras anatómicas torácicas. Se tomaron imágenes de los órganos torácicos de 3 gatos adultos por TC y luego se plastinaron en este estudio. Las muestras se plastinaron en la misma posición corporal en el proceso de obtención de imágenes TC. Las imágenes de TC y las secciones transversales plastinadas correspondientes se compararon entre sí. Las estructuras anatómicas de la cavidad torácica en los preparados plastinados estaban de acuerdo con las imágenes de CT. Además de las estructuras óseas, otros órganos como el esófago, la tráquea, el corazón con vasos relacionados, los pulmones y los músculos torácicos estaban bien definidos en las imágenes de TC y los plastinados. Por otra parte, se captaron bien las imágenes reconstruidas en 3D de las estructuras anatómicas de la cavidad torácica. Pensamos que este estudio es beneficioso para la cirugía veterinaria y los campos de radiología, así como también para la educación de anatomía veterinaria.
- Published
- 2018
38. Yetişkin ve Kastre Edilmiş Erkek Ratlarda Yüksek Doz Testosteron Propiyonatın İndüklediği Kardiyak Fibrozis Üzerine Lonidamin Yüklü Lipit-Polimer Hibrit Nanopartiküllerin Etkisi
- Author
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ALÇIĞIR, Mehmet Eray, ŞENGEL TÜRK, Ceyda Tuba, EKİM, Okan, and HASÇİÇEK, Canan
- Subjects
Fen ,Cardiac fibrosis,Lonidamine hydrochloride,Testosterone,Rat ,Science ,Kardiyak fibrozis,Lonidamin hidroklorür,Testosteron,Sıçan - Abstract
In recent years,the usage of exogenous testosterone has tripled in humans. Although, mechanismhas not yet been fully elucidated, there is a correlation between the increasedrisk of heart failure and testosterone usage. The aim of this study was todemonstrate cardiac fibrosis, which a main finding of hearth failure, intestosterone propionate-applied male rats and to show its regression byLonidamine as an anti-hyperplastic agent. A total of 72 adult Wistar albino andneutralized male rats were divided into 4 groups (n=18 in each groups). Animalsin all groups were received to testosterone propionate until 2nd, 4th, and 12thweeks (n=6 in each groups). Subsequently, group I and II also received the puresolution of Lonidamine hydrochloride and its lipid-polymer hybridnanoparticulate formulation via intraprostatic injection. Group III, blanklipid-polymer hybrid nanoparticle formulation were solely administrated via sameway. The control group or group IV were received only testosterone. At the endof the experiment period, hearts were collected and fibrocytic changes wereconfirmed by histochemical and immunohistochemical methods.Histopathologically, fibrosis were lower in group I and II when comprared tothat of group III and IV. Imunohistochemically, bFGF, cyclin D1 and p16 proteinexpressions were evaluated. bFGF and cyclinD1 epxressions correspondingly toincreasing fibrosis were found higher in last two groups during the experiment.But, p16 expressions were lower in Lonidamine treated-group I and II. Inconclusion, results of this study supported that testosterone propionate maypromote cardiac fibrosis. Lonidamine hydrochloride may be used in itsprevention of fibrosis., Son yıllarda,insanlarda ekzojen testosteron kullanımı üç katına çıkmıştır. Mekanizma henüztam olarak aydınlatılmamış olmasına rağmen kalp yetmezliği riskini arttırdığınadair bir korelasyon vardır. Bu çalışmanın amacı, erkek sıçanlarda testosteronpropiyonat kullanımının kalp yetmezliğinin temel bulgusu olan fibrozise yolaçtığını ve bir anti-hiperplastik ajan olan Lonidaminin bunu gerileticietkisini göstermekti. Çalışmada, toplam 72 adet kastre edilmiş, yetişkin Wistaralbino erkek sıçan kullanıldı ve hayvanlar 4 ana gruba ayrıldı (her bir gruptaiçin n= 18). Bu ana gruplar 3 alt grubaayrılarak (n=6 her bir grup için) hayvanlara, 2., 4. ve 12. haftalara kadartestosteron propiyonat uygulandı. Group I ve II için, Lonidamin hidroklorür,saf çözelti içinde ve bunun lipit-polimer hibrit nanopartikül formülasyonuhalinde prostatlara enjekte edildi. Grup III için sadece lipit-polimer hibritnanopartikül formülasyonu uygulandı. Kontrol grubu olarak grup IV’de sadecetestesteron uygulandı. Çalışmanın sonunda kalpler toplandı. Histopatolojikolarak fibrosis grup I ve II’de grup III ve IV’dekiyle karşılaştırıldığındadaha düşüktü. İmmünohistokimyasal olarak bFGF, siklin D1 ve p16 proteinekspresyonları değerlendirildi. Son iki grupta, artan fibrozise karşılık gelenbFGF ve siklinD1 ifadeleri, deney sırasında daha yüksek bulundu. Ancak, p16ifadeleri Lonidamin uygulanan grup I ve grup II’de daha düşüktü. Sonuç olarak,bu sonuçlar testosteron propiyonatın kardiyak fibrozisi etkileyebileceğinidesteklemektedir ve fibrozisin önlenmesinde Lonidamin hidroklorürkullanılabilir.
- Published
- 2018
39. Efficiency evaluation of different silicone plastination protocols applied to domestic avian specimens
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EKİM, Okan
- Subjects
Anatomi,kanatlı,plastinasyon ,Anatomy,avian,plastination - Abstract
Anatomikörneklerin hazırlanması ve muhafazası için birçok farklı metot bulunsada,plastinasyon tekniği ile üretilenler oldukça dayanıklı, doğala özdeş ve insansağlığı için zararsız son ürünler olmaktadır. Plastinasyon teknikleri içerisindeen sık kullanılanı silikon plastinasyonudur. İnsana ait örneklerin yanı sırabirçok farklı hayvan türü üzerinde de eğitim, araştırma vb. amaçlarla silikonplastinasyonu tekniği denenmiştir. Fakat kanatlı hayvanlar üzerinde yapılan çalışmalaroldukça sınırlı kalmıştır. Bu çalışmada 8 adet tavuk, 8 adet evcil ördek ve 8adet bıldırcın kullanıldı. Örnekler üzerinde silikon plastinasyonunun her bir aşamasıtakip edildi ve her aşamadaki parametreler kaydedildi. Bu çalışmanın temel amacı;evcil kanatlı hayvanlarda silikon plastinasyonu metodunu uygulamaktı. Ayrıcadaha önce kanatlıların plastinasyonunu temel alan detaylı bir çalışma yürütülmemişolması sebebiyle, bu türlere özgü bir silikon plastinasyon protokolü geliştirilmeside amaçlandı., Although thereare many different methods for the preparation and preservation of anatomicspecimens, pieces produced using the plastination technique are quite durable,natural identical and harmless final productsfor human health. Silicone plastination is the most frequently usedplastination technique. In addition to human specimens, this technique has beenapplied to various animal species, for the purpose of education, research andetc. However, studies focused on avian species are quite limited. In thisstudy, 8 chickens, 8 domestic ducks and 8 quails were used. Different siliconeplastination steps were followed on the specimens and parameters were recordedat each step. The main purpose of this study is; to apply the siliconeplastination method in domestic avian species. It was also aimed to develop asilicone plastination protocol specific for avian species since a detailedstudy based on the plastination of birds has not been conducted before.
- Published
- 2017
40. Sectional Evaluation of Anatomic Structures in Cat (Felis catus) Thoracic Cavity by Computed Tomography Imaging and Silicone Plastination Methods
- Author
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Akgün, Remzi Orkun, primary, Bakici, Caner, additional, Ekim, Okan, additional, Bumin, Ali, additional, and Önder-Orhan, Ismail, additional
- Published
- 2018
- Full Text
- View/download PDF
41. Stereological estimation of volume ratios of chest muscle in Atak-s hybrid with Rhode Island Red and Barred Rock pure lines by magnetic resonance imaging
- Author
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OTO, Çağdaş, BAKICI, Caner, TUNCA, Muhammet, EKİM, Okan, ÖZEN, Doğukan, KAMANLI, Serdar, and ÇAKIR, Ahmet
- Subjects
ATAK-S,Cavalieri principle,magnetic resonance imaging,pectoral muscle,stereology ,ATAK-S,Cavalieri prensibi,göğüs kasları,manyetik rezonans görüntüleme,stereoloji - Abstract
Bu çalışmada ülkemizde yetiştirilen ilk yumurtacı yerli hibrit olan ATAK-S ile bu hibritlerin ebeveynleri olan RhodeIsland Red (RIR) ve Barred Rock (BAR)hatlarında göğüs kaslarının hacim oranlarınınmanyetik rezonans (MR) görüntüleme ile in-vivo olarak belirlenmesi ve ırklar arası karşılaştırma yapılması amaçlandı. Araştırma materyali olarak 10’ar adet, 50 haftalık RIR, BAR ebeveyn hatları ve ATAK-S hibritleri kullanıldı. 3.0 Tesla MR taramayla elde edilen görüntüler ile fiziksel kesitler Stereo Investigator 10.50 yazılım programında Cavalieri hacim hesaplama metodu kullanılarak değerlendirildi. Transversal kesit görüntüleri üzerinden yapılan ölçümlerde göğüs kas hacminin toplam vücut hacmine oranı ortalama olarak ATAK-S için; 0,140±0,003, RIR için; 0,129±0,006, BAR için; 0,128±0,002 olarak belirlendi. Sonuç olarak ATAK-S, RIR ve BAR ırkları arasında yapılan bu karşılaştırmalı hacim oranı ölçüm çalışmasında, üç ırkın göğüs hacim oranları değerlendirildi. ATAK-S hibritinde göğüs kası hacim oranlarının ebeveyn hatlara göre daha yüksek olduğu görüldü., In-vivo determination of thevolume ratio of breast muscles among the firstlocal laying hybrid chicken and its parents Rhode Island Red (RIR) and Barred Rock (BAR) by using magnetic resonance (MR) imaging technique with Cavalieri principle and comparing of these data between the three breeds were aimed in this study. Ten pair of 50 weeks old RIR, BAR and ATAK-S hybrid breeds were used as research subjects. After scanning of the whole body with 3.0 Tesla MR scanner, cross-sections were taken from the same levels with the MR images and photographed. The parameters obtained from MR images and physical sections were evaluated with Cavalieri principle by using Stereo Investigator 10.50 software. The ratios of the chest muscle volume to the total body volume on the transversal cross-sectional images for ATAK-S, RIR and BAR are 0.140± 0.003, 0.129 ± 0.006 and 0.128 ± 0.002 respectively. As a result, comparative breast volume ratio measurements between three breeds were evaluated (ATAK-S, RIR and BAR) in this study. The volume ratios of the pectoral muscles in ATAK-S hybrid chicken were higher than the parents.
- Published
- 2017
42. Textbook of Veterinary Anatomy Fourth Edition
- Author
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KARAN, MERYEM, KARADAĞ, HÜSEYİN, TIPIRDAMAZ, SAADETTİN, AKOSMAN, MURAT SIRRI, BAHADIR, ALİ, ARICAN, İLKER, YILMAZ, SADIK, ORHAN, İSMAİL ÖNDER, OTO, ÇAĞDAŞ, ONUK, BURCU, KABAK, MURAT, Bozkurt, Emine Ü, EKİM, OKAN, ÇAKIR, AHMET, HAZIROĞLU, REŞİDE MERİH, ATEŞ, SEVİNÇ, KARA, MEHMET ERKUT, YILDIZ, BAHRİ, DABANOĞLU, İLKNUR, ÖZGEL, ÖZCAN, ÇEVİK DEMİRKAN, AYSUN, ERDEN, HASAN, BEŞOLUK, KAMİL, ÖZKAN, ZAİT ENDER, GÜLTİKEN, MURAT ERDEM, YILDIZ, DİNÇER, GEZER İNCE, NAZAN, PAZVANT, GÜLSÜN, ONAR, VEDAT, KAHVECİOĞLU, KİFAYET OYA, BAKICI, CANER, Özdemir, Derviş, YILDIZ, HÜSEYİN, KILINÇ, MEHMET, TURAN, ERKUT, ERDOĞAN, SERKAN, EKEN, EMRULLAH, HALIGÜR, AYŞE, NUR, İSMAİL HAKKI, DÜZLER, Ayhan, and ALAN, Aydın
- Published
- 2016
43. 3 tesla magnetic resonance imaging and multiplanar reconstruction of the brain and its associated structures in sheep.
- Author
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BAKICI, Caner, EKİM, Okan, ERGİN, İrem, ALGIN, Oktay, and OTO, Çağdaş
- Subjects
- *
MAGNETIC resonance imaging , *IMAGE reconstruction , *SHEEP , *THREE-dimensional imaging , *BRAIN imaging - Abstract
The purpose of the study was to scan the brain and related structures in sheep with high-resolution magnetic resonance imaging (MRI) and three-dimensional (3D) multiplanar reconstruction for defining the anatomical regions. Six adult sheep, three of six were male and three of six were female used as cadaver, were utilized in this research. Heads were scanned at 3 Tesla Siemens Magnetom Spin-Echo MRI devices using the human head coil. The processes were acquired in both T1 and T2 weighted slices and were reconstructed by using Leonardo workstation. The cranioencephalic structures and anatomical details were defined and labeled in all slice of 3 planes that were obtained 1 mm thickness sequential images in sagittal, frontal, and transversal planes. According to the MRI measurements obtained intracranially from the brain, the average value of length, height, and width of the brain were 87.1 ± 0.3, 46.8 ± 0.7, and 62.2 ± 0.4 mm, respectively. It was observed that in T1 weighted images were more effective to identify deep brain structures and anatomical details. On 3D reconstructed images obtained from the study can be used as a reference in head and brain MR scans in multidisciplinary studies where sheep are used as animal models. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
44. 3 Tesla Magnetic resonance imaging and multiplanar reconstruction of the brain and its associated structures in pig
- Author
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OTO, Çağdaş, EKİM, Okan, ALGIN, Oktay, ŞENEL, O. Oytun, İNCE, Nazan, and HAZIROGLU, R. Merih
- Subjects
Anatomi,beyin,domuz,manyetik rezonans görüntüleme ,Anatomy,brain,magnetic resonance imaging,pig ,Veterinary ,General Veterinary ,Veteriner Hekimlik ,Animal Science and Zoology - Abstract
Determination of 3 Tesla MR imaging appearance of the brain and associated structures was the aim of this study. T1 and T2-weighted (W) and 3D reformatted images obtained from 6 adult pigs were used to define the cranioencephalic structures and anatomic details in three planes. Relevant structures were identified and labeled at each level. Especially T1W images scanned with three-dimensional inversion recovery multiplanar reconstruction (3D-IR-MPR) sequence provided excellent visualization for the inner structures of head and brain, Bu çalışmada, domuzda beyin ve ilişkili yapıların 3 Tesla MR ile görüntülenmesi amaçlandı. Çalışmada 6 adet yetişkin domuza ait T1 ve T2-ağırlıklı imajlar ile 3 boyutlu rekonstrukte edilmiş görüntüler kullanıldı. Cranioencephalic yapılar ve anatomik detaylar üç planda ve her kesit üzerinde tanımlanarak işaretlendi. Özellikle 3D-IR-MPR sekansı ile alınan T1-ağırlıklı görüntüler, baş ve beyine ait derin yapıların mükemmel düzeyde görüntülenmesini sağladıDetermination of 3 Tesla MR imaging appearance of the brain and associated structures was the aim of this study. T1 and T2-weighted (W) and 3D reformatted images obtained from 6 adult pigs were used to define the cranioencephalic structures and anatomic details in three planes. Relevant structures were identified and labeled at each level. Especially T1W images scanned with three-dimensional inversion recovery multiplanar reconstruction (3D-IR-MPR) sequence provided excellent visualization for the inner structures of head and brain
- Published
- 2011
45. Comparison of Different Anesthetic Protocols for Morphometric Measurements of Carp (Cyprinus carpio)
- Author
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Çağiltay, Ferhat, primary, Atanasoff, Alexander, additional, Sağlam, Mehmet, additional, Çağatay, Soner, additional, Nikolov, Galin, additional, Ekim, Okan, additional, and Seçer, Faik Sertel, additional
- Published
- 2017
- Full Text
- View/download PDF
46. Silicone plastination of kidneys in domestic mammals with cold temperature technique
- Author
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EKİM, Okan, TUNALI, Selçuk, HAZIROĞLU, R. Merih, AYVALI, Muharrem, TOBB ETU, Faculty of Medicine, Department of Basic Medical Sciences, TOBB ETÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tunalı, Selçuk, and M-8113-2014
- Subjects
kidney ,plastination ,plastinasyon ,Anatomy,kidney,plastination ,Anatomi,böbrek,plastinasyon ,böbrek ,Anatomi ,Anatomy - Abstract
Plastinasyon kısaca; doku sıvılarının reaktif bir polimer ile yer değiştirmesiyle karakterize bir anatomik preparat hazırlama tekniği olarak tanımlanabilir. Plastinasyon, diğer birçok anatomik yönteme kıyasla daha zorlu ve ekonomik açıdan maliyetli olsa da ortaya çıkan örneklerin doğal görüntüsüne son derece benzer, ayrıca dayanıklı ve insan sağlığı için zararsız son ürünler olmaları, bu yöntemi konuyla ilgilenen bilim insanları için gittikçe aranır hale getirmiştir. Plastinasyon teknikleri içerisinde en sık kullanılanı ve örneklerin estetik açıdan etkileyici görünmesi sebebiyle toplumda en bilinir olanı kuşkusuz silikon plastinasyonudur. Silikon plastinasyonu temel olarak 5 aşamadan oluşmaktadır. Bu aşamalar sırasıyla örneklerin hazırlanması, dehidrasyon, yağdan arındırma, zorlu impregnasyon ve gaz kürleme-sertleştirme olarak özetlenebilir. Silikon plastinasyonu protokolünün titizlikle uygulanması ve her aşamadaki parametrelere dikkat edilmesi, son ürünün istenilen amaca uygun olması açısından son derece önemlidir. Bu çalışma için iki adet köpek böbreği, iki adet merkep böbreği ile iki adet sığır böbreği kullanılmıştır. Organların plastinasyonu sırasında, her aşamadaki parametreler kaydedilmiştir. Çalışmanın amacı; evcil memeli hayvan böbreklerinin soğuk ortam tekniği ile silikon plastinasyonunu detaylarıyla anlatmak, bu tekniğin hangi alanlarda kullanılabileceği yönünde değerlendirmeler yapmak, böylelikle ülkemizde konuyla ilgilenen bilim insanlarına kılavuz olabilecek nitelikte bir kaynak ortaya koymaktır, Briefly plastination can be defined as an anatomic specimen preparation technique which is characterized as replacement of tissue fluids with a reactive polymer. However plastination is a difficult and economically high cost technique when compared with the other methods, the final products are quite similar to the natural appearance and they are also very durable and non-hazardous. These features have made this method very popular for the relevant scientists. Silicone plastination is the most oft-used and because of the esthetical outlook of the final products the most well-known technique among all plastination methods. Silicone plastination consists of 5 main stages. These are preparation of specimens, dehydration, defatting, forced impregnation and gas curinghardening respectively. To obtain a convenient plastinate these stages should be handled meticulously and the parameters in every stage should also be monitored carefully. Kidneys of two dogs, two donkeys and two cattles were plastinated for this study. The parameters in every stage were recorded. The aim of this study is to indicate the silicone plastination of the domestic mammals’ kidneys with cold temperature technique in detailed manner, to evaluate the scientific fields in which the plastination can be used conveniently and therefore produce a guide document for the relevant scientists in our country
- Published
- 2015
47. Preparation of Internal Genital Organs of Adult Cows by S10B Silicone Plastination Method.
- Author
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AKGÜN, Remzi Orkun, EKİM, Okan, BAKICI, Caner, İNSAL, Burcu, AYVALI, Muharrem, ORHAN, İsmail Önder, OTO, Çağdaş, and ATANASOFF, Alexander
- Subjects
- *
GENITALIA , *REACTIVE polymers , *ORGANS (Anatomy) , *COWS , *BIOLOGICAL specimens - Abstract
It is essential to demonstrate organs and their structures practically in anatomy education. Plastination is an anatomical technique that has been used to prepare biological specimens for educational purposes. it is a gradual process by replacement of fluids in biological tissues with reactive polymers such as silicone, epoxy or polyester resin. This study was aimed to plastinate the internal genital organs of adult cows by S10B silicone plastination method. Ten internal genital organs of cows were plastinated to be used in veterinary undergraduate teaching/practices. After dissection and fixation, the specimens were plastinated with S10B plastination method and colour differentiation of the organ parts were measured. The plastination process was completed with dehydration, defatting, impregnation, and gas curing stages, respectively. It was observed that the plastination of specimens with S10B plastination method preserve normal anatomy of genital organs. It was estimated that all parts of uterus became greenish and bluish colour and the value of the brightness of uterus was increased. The tissue shrinkage was reduced considerably when dehydration was carried out in a cold environment. It was concluded that S10B plastination method can be easily used to prepare the specimens of genital organs to be used in veterinary teaching. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
48. Comparison of the volume fraction values of grey matter on the cervical enlargement of the spinal cord in chicken and quail.
- Author
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BAKICI, Caner, OTO, Çağdaş, EKİM, Okan, AHLAT, Ozan, ÖZEN, Doğukan, and ÇAKIR, Ahmet
- Subjects
MORPHOMETRICS ,VETERINARY medicine ,ULTRASONIC imaging ,JAPANESE quail ,WHITE matter (Nerve tissue) ,MULTIVARIATE analysis - Abstract
Copyright of Veterinary Journal of Ankara University / Ankara Universitesi Veteriner Fakultesi Dergisi is the property of Ankara University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
49. Yılanlarda Soğuk Ortam Tekniği ile Tüm Vücut Silikon Plastinasyonu
- Author
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EKİM, Okan, İNSAL, Burcu, BAKICI, Caner, HAZIROĞLU, R. Merih, and AKGÜN, R. Orkun
- Subjects
Anatomy,plastination,reptile,snake ,Anatomi,plastinasyon,sürüngen,yılan - Abstract
The main principle of the plastination is to replace the tissue fluids in the specimen with a reactive polymer through the medium of an organic solvent. Low temperature silicone plastination has 5 main steps as is known. However these steps can be changed or modified depending on the anatomical or histological features of the specimen. Preparation and long-time preservation of reptile specimens need virtuosity, experience and a steady anatomic method either. Plastination can be a convenient alternative for that. However, studies based on the plastination of the squamata are quite insufficient. The aim of this study was to evaluate the lowtemperature whole body silicone plastination of scaled reptiles in detailed manner and to compare the plastination procedures of reptiles and the other mammals. It is also aimed to create a protocol for the silicone plastination of squamata. Two freshwater snakes and two blacksnakes were used for this study. Samples were processed to the short-term formalin fixation, dehydration, impregnation, and gas curing-hardening procedures respectively. Although defatting is in the standard procedure of plastination, this stage was skipped. The specified parameters such as temperature, time or concentration were recorded regularly in each step. We preferred short term formalin fixation for the specimens to preserve the natural colour and the morphology. Although the colour of the skin became a bit darker, the short term formalin fixation was considered as efficient. Two times of acetone bath was satisfying for the dehydration stage. Silicone impregnation stage took short period of time than expected. Plastinated specimens were not only elastic but also durable enough to use as teaching materials in the reptile anatomy lectures of our faculty, Plastinasyon; örnek içerisindeki doku sıvılarının, organik bir solvent aracılığıyla, reaktif bir polimer ile yer değiştirmesidir. Bilindiği üzere soğuk ortam silikon plastinasyonunun 5 temel aşaması vardır. Bu aşamalar plastine edilecek preparatın anatomik ve histolojik özelliklerine göre değiştirilebilir veya modifiye edilebilir. Sürüngen örneklerinin hazırlanması ve uzun süre muhafazasının sağlanabilmesi, güvenilir bir anatomik metot, teknik beceri ve deneyim gerektirir. Bu bağlamda plastinasyonun amaca uygun bir yöntem olarak öne çıkmasına rağmen, pullu sürüngenlerin plastinasyonu üzerine kurgulanmış makaleler oldukça yetersizdir. Bu çalışmanın amacı; pullu sürüngenlerin soğuk ortam tekniğiyle tüm vücut silikon plastinasyonunu detaylarıyla değerlendirmek, memeli ve sürüngen plastinasyon prosedürlerini birbiriyle karşılaştırmaktır. Ayrıca pullu sürüngenlerin plastinasyonu için bir protokol oturtmak da amaçlanmıştır. Bu çalışma için iki adet tatlı su yılanı ile iki adet karayılan kullanılmıştır. Örnekler sırasıyla kısa süreli fiksasyon, dehidrasyon, impregnasyon ve gaz kürleme-sertleştirme işlemlerine tabi tutulmuş, yağdan arındırma aşaması temel adımlardan biri olmasına rağmen uygulanmamıştır. Her aşamada sıcaklık, konsantrasyon, süre gibi parametreler düzenli olarak kaydedilmiştir. Örneklerin doğal morfolojik özelliklerini koruması ve derinin doğal rengini kaybetmemesi için kısa süreli formalin fiksasyonu tercih edilmiştir. Deri renginin biraz kararmasına rağmen bu fiksasyon tekniğinin amaca uygun olduğu düşünülmüştür. Dehidrasyon aşamasında 2 defa uygulanan aseton banyosu yeterli görülmüştür. İmpregnasyon süreci beklenenden kısa sürede tamamlanmıştır. Plastine edilen örneklerin sadece elastik değil, aynı zamanda sürüngen anatomisi derslerinde kullanılabilecek kadar dayanıklı olduğu görülmüştür.
- Published
- 2014
50. Magnetic resonance (MR) imaging of the carpal tunnel and related structures in New Zealand Rabbit (Oryctolagus cuniculus): An anatomic and radiologic evaluation on an animal model
- Author
-
EKİM, Okan, OTO, Çağdaş, and ALGIN, Oktay
- Subjects
body regions ,Veterinary ,15 kanallı alıcı-verici koil,anatomi,karpal tünel,manyetik rezonans görüntüleme,tavşan ,Veteriner Hekimlik ,15 channel transmit-receive coil,anatomy,carpal tunnel,magnetic resonance imaging,rabbit - Abstract
The aim of this study was to determine the anatomical structures in carpal region with the routine T1, T2 weighted (W) and three-dimensional (3D) magnetic resonance (MR) sequences that are frequently being used for the diagnosis and the treatment of the wrist disorders and to indicate the efficacy of MR imaging (MRI) on the rabbit’s carpal region which can be a convenient wrist model especially for the carpal tunnel syndrome. It is also aspired to compare the image features obtained from 1.5 and 3 Tesla MR units in terms of anatomy and radiology. Five adult New Zealand rabbits were used in this study. Wrists were scanned in neutral position by 1.5 and 3 Tesla MR devices with a loop coil and a 15-channel transmit-receive birdcage coil respectively. Anatomy of the carpal tunnel was well defined in T1W transverse images in 1.5 Tesla MRI. The median nerve was imaged with greater signal intensity on T2W sequences. In 3 Tesla MRI, the anatomical structures in carpal region could easily be evaluated on high resolution 3D sequences with isotropic voxels and also with the help of thin section reformatted images. According to our results, 3D sequences with isotropic voxel sizes by 15-channel transmit-receive birdcage coil in 3 Tesla MRI device seems to be more efficient than the other routine two-dimensional sequences in 1.5 Tesla MRI for the assessment of carpal tunnel anatomy, diagnosis and treatment of disorders both in humans and in animals. This process also decreases the MRI time and specific absorption rate (SAR) values, Bu çalışmanın amacı; el bileği bölgesindeki rahatsızlıkların teşhis ve tedavisinde kullanılan rutin T1, T2 Ağırlıklı (A) ve 3 boyutlu manyetik rezonans (MR) sekanslarının yardımıyla, karpal bölgedeki anatomik oluşumları belirlemek ve manyetik rezonans görüntülemenin, özellikle karpal tünel sendromu için uygun bir bilek modeli olabilecek tavşan karpal bölgesi üzerindeki etkinliğine işaret etmektir. Ayrıca 1,5 ve 3 Tesla MR cihazlarından elde edilen görüntü özelliklerinin anatomik ve radyolojik açıdan karşılaştırılması da amaçlanmıştır. Bu çalışma için 5 adet Yeni Zelanda Tavşanı’ndan faydalanılmıştır. El bilekleri nötral pozisyonda sırasıyla 1,5 Tesla MR cihazında, halka tipi koil ile ve 3 Tesla MR ünitesinde, 15 kanallı alıcı-verici kafes tipi koil ile tarandı. 1,5 Tesla MR görüntülemede; T1 A transversal imajlarda carpal tünel daha iyi belirlendi. T2 A sekanslarda nervus medianus yüksek sinyal yoğunluğu gösterdi. 3 Tesla MR görüntülemede; karpal bölgedeki anatomik yapılar izotropik vokselli 3 boyutlu sekanslar ve ayrıca ince kesit reformat görüntülerin de yardımıyla rahatlıkla değerlendirilebildi. Sonuçlarımıza göre; hem insan hem de hayvanlarda karpal tünel anatomisinin değerlendirilmesi, rahatsızlıkların teşhis ve tedavisi için izotropik voksel 3 boyutlu sekanslar ve 15 kanal alıcı-verici koil vasıtasıyla çekilen 3 Tesla MR görüntülemenin, 1,5 Tesla MR görüntülemede kullandığımız 2 boyutlu sekanslara göre daha etkin olduğu görülmektedir. Ayrıca bu işlem MR görüntüleme zamanını kısaltmakta ve SAR değerlerini de düşürmektedir
- Published
- 2014
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