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10 results on '"E.P. Moll van Charante"'

1. Autonomic regulation in different hypertensive phenotypes - the HELIUS study

Author

D. Collard, E.M.C. Vriend, H. Galenkamp, E.P. Moll van Charante, L. Vogt, B.E. Westerhof, and B.J.H. van den Born

Subjects
helius study, hypertension, phenotypes, autonomic function, ish, idh, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Background: Hypertension can be classified into different phenotypes based on systolic and diastolic blood pressure (BP) that carry a different prognosis and may therefore be differently associated with sympathetic activity. We assessed the association between cardiac autonomic function determined from continuous finger BP recordings and hypertensive phenotypes. Methods: We included 10,221 individuals aged between 18-70 years from the multi-ethnic HELIUS study. Finger BP was recorded continuously for 3-5 minutes from which cross-correlation baroreflex sensitivity (xBRS) and heart rate variability (HRV) were determined. Hypertension was classified into isolated systolic (ISH; ≥140/40 years) and sex, using regression with correction for relevant covariates. For xBRS, values were log-transformed. Results: In younger adults with ISH, xBRS was comparable to normotensive individuals in men (ratio 0.92; 95%CI 0.84-1.01) and women (1.00; 95%CI 0.84-1.20), while xBRS was significantly lower in IDH and SDH (ratios between 0.67 and 0.80). In older adults, all hypertensive phenotypes had significantly lower xBRS compared to normotensives. We found a similar pattern for HRV in men, while in women HRV did not differ between phenotypes. Conclusions: In younger men and women ISH is not associated with a shift towards increased sympathetic control, while IDH and SDH in younger and all hypertensive phenotypes in older participants were associated with increased sympathetic control. This suggests that alterations in autonomic regulation could be a contributing factor to known prognostic disparities between hypertensive phenotypes.

Published
2023
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2. Differences in the prevalence of intermediate hyperglycaemia and the associated incidence of type 2 diabetes mellitus by ethnicity: The HELIUS study

Author

C.C. van Olden, M. Muilwijk, K. Stronks, B.J. van den Born, E.P. Moll van Charante, M. Nicolau, A.H. Zwinderma, M. Nieuwdorp, A.K. Groen, I.G.M. van Valkengoed, Epidemiology and Data Science, Internal medicine, ACS - Diabetes & metabolism, AGEM - Endocrinology, metabolism and nutrition, Graduate School, ACS - Atherosclerosis & ischemic syndromes, Amsterdam Gastroenterology Endocrinology Metabolism, APH - Health Behaviors & Chronic Diseases, Public and occupational health, APH - Methodology, Vascular Medicine, APH - Global Health, APH - Personalized Medicine, General practice, Experimental Vascular Medicine, and ACS - Heart failure & arrhythmias

Subjects
Glycated Hemoglobin, Male, Diabetes Mellitus type 2, HELIUS-study, endocrine system diseases, Incidence, Endocrinology, Diabetes and Metabolism, nutritional and metabolic diseases, General Medicine, Ghana, Endocrinology, Diabetes Mellitus, Type 2, Hyperglycemia, Intermediate hyperglycaemia, Prevalence, Ethnicity, Internal Medicine, Humans, Female, Minority Groups, Netherlands
Abstract

Aims: We aimed to describe differences in the prevalence of intermediate hyperglycaemia (IH) between six ethnic groups. Moreover, to investigate differences in the association of the classifications of IH with the incidence of T2DM between ethnic groups. Methods: We included 3759 Dutch, 2826 African Surinamese, 1646 Ghanaian, 2571 Turkish, 2691 Moroccan and 1970 South Asian Surinamese origin participants of the HELIUS study. IH was measured by fasting plasma glucose (FPG) and HbA1c. We calculated age-, BMI and physical-activity-adjusted prevalence of IH by sex, and calculated age and sex-adjusted hazard ratios (HR)for the association between IH and T2DM in each ethnic group. Results: The prevalence of IH was higher among ethnic minority groups (68.6–41.7%) than the Dutch majority (34.9%). The prevalence of IH categories varied across subgroups. Combined increased FPG and HbA1c was most prevalent in South-Asian Surinamese men (27.6%, 95 %CI: 24.5–30.9%), and in Dutch women (4.2%, 95 %CI: 3.4–5.1%). The HRs for T2DM for each IH-classification did not differ significantly between ethnic groups. HRs were highest for the combined classification, e.g., HR = 8.1, 95 %CI: 2.5–26.6 in the Dutch. Conclusion: We found a higher prevalence of IH in ethnic minority versus majority groups, but did not find evidence for a differential association of IH with incident T2DM.

Published
2022

4. 6 Buik

Author

E.P. Moll van Charante

Published
2015

5. De huisartsenkliniek in IJmuiden

Author

Elsbeth Voogt, E.P. Moll van Charante, C.J.J.M. IJzermans, Esther Hartman, Niek S. Klazinga, and Patrick J E Bindels

Subjects
Family Practice
Abstract

Moll van Charante EP, Hartman EE, IJzermans CJ, Voogt E, Klazinga NS, Bindels PJE. De huisartsenkliniek in IJmuiden. Een bijzonder transmuraal experiment. Huisarts Wet 2005;48(3):102-8.

Published
2005

6. Van spelverdeler tot speelbal?gezondheidszorg huisarts huisartsgeneeskunde Woudschoten

Author

C.J.J.M. IJzermans, E.P. Moll van Charante, Niek S. Klazinga, and D.M.J. Delnoij

Subjects
Family Practice
Abstract

Hoewel de huisarts over een periode van 50 jaar zijn positie in het Nederlandse zorgstelsel goed heeft weten te consolideren, staan deze verworvenheden anno 2002 weer onder druk. Beschreven worden de veranderingen in het takenpakket en de hieruit resulterende toegenomen werkdruk. Ten gevolge van schaalvergroting van vele institutionele zorgaanbieders en het ontstaan van zorgketens zijn ook de samenwerkingsrelaties met de huisarts ingrijpend veranderd. Verdere differentiatie in de vormgeving van het huisartsenberoep wordt bepleit, evenals aanpassingen in de organisatie van de huisartsenzorg. Dit vraagt om een herziening van het basistakenpakket en een herdefiniering van de poortwachtersrol.

Published
2002

7. Buik

Author

E.P. Moll van Charante

Published
2010

8. A cost study of a general practitioner hospital in the Netherlands

Author

E.P. Moll van Charante, Frans F. H. Rutten, C. J. Yzermans, Leona Hakkaart-van Roijen, Patrick J E Bindels, Erasmus School of Health Policy & Management, ACS - Amsterdam Cardiovascular Sciences, APH - Amsterdam Public Health, General practice, and Other departments

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Hospitals, Community, Health care, Medicine, Humans, Hospital patients, Alternative care, Hospital Costs, health care economics and organizations, Aged, Netherlands, Rehabilitation, business.industry, Length of Stay, medicine.disease, Home Care Services, Hospital Charges, Emergency medicine, Costs and Cost Analysis, Female, Medical emergency, business, Nursing homes, Family Practice, Cost study
Abstract

OBJECTIVE: To perform a cost study of the first general practitioner (GP) hospital in the Netherlands. METHODS: We conducted a cost study in a GP hospital in the Netherlands. Data on healthcare utilisation from 218 patients were collected for a period of one year. The costs of admission to the GP hospital were compared with the expected costs of the alternative mode of care. In the GP hospital three types of bed categories were distinguished: GP beds (admission and discharge by GPs, n=131), rehabilitation beds (recovery from hospital surgery, n=62) and nursing home beds (hospital patients awaiting a vacancy in a nursing home, n=25). GPs were interviewed to indicate the best alternative form of healthcare for the GP bed patients in the absence of a GP hospital (dichotomised for this study into "hospital" or "home care"). For the "rehabilitation" and "nursing home" patients the alternative care mode was admission to a hospital. RESULTS: The mean length of stay was 15 days for the GP beds, 31 days for the rehabilitation beds and 90 days for the nursing home beds. For the GP bed patients the costs were 2533 euros per admission compared with 3792 euros for hospital stay. For the group of GP bed patients for whom "home care" was the best alternative, the costs were 2494 euros for GP hospital days compared with 2814euros , the average cost for home care of patients of 65 years and older. For rehabilitation patients the costs per patient were 4744 euros compared with 8041 euros in a hospital. For patients waiting for admission to a nursing home, these costs were 13,143 euros and 22,670 euros respectively. CONCLUSION: The GP hospital might be a cost-saving alternative for elderly patients in need of intermediate medical and nursing care between hospital and home care. Further research on the cost-effectiveness of the GP hospital compared with home care and nursing home care is needed

Published
2004

9. Front & Back Matter

Author

Anthony Martyr, Melanie Luppa, Christian Schmidt, Oskar Hansson, Z. Pernber, Yoon Hee Hong, Marion Eisele, Douglas Hägerström, Ann-Katrin Edlund, J. Gyllenborg, David Genís, Michael Pentzek, So Young Moon, Tamar Freud, H. Grønning, Kalle Spångberg, Henrique Barros, Jing Yang, J.-S. Vidal, Hans-Helmut König, Y.-H. Wu, Alex Berzak, Kaj Blennow, Laia Calvó-Perxas, Masayuki Nakamura, Henrik Zetterberg, Angela Fuchs, S.A. Ligthart, Boris Punchik, Lennart Minthon, Toshiro Fujimoto, Ho Sung Kim, R.B. Dessau, Erik Stomrud, B. Schmand, Inga Zerr, Milton Severo, J. de Rotrou, Laia Febrer, Akira Sano, Horst Bickel, Sílvia Fraga, M. Blomqvist, Franziska Tebarth, Maria Aguirregomozcorta, E. Richard, Natàlia Vallmajó, Tae Sung Lim, David S. Geldmacher, Martin R. Farlow, Elisabet Londos, Birgitt Wiese, C. Thomas-Antérion, Thomas Zimmermann, Jun Young Choi, Maria Eriksdotter-Jönhagen, Martin Wolff, P. Eikelenboom, S.C. Yang, Erik Ryding, Margaret Moline, Hyun Young Lee, Janine Stein, Luan Cen, Takanori Ishizuka, Hui Fang Shang, Arash Rahmani, Rui Huang, Hai Chun Shi, Mio Ichiba, Jochen Werle, Jana Prokein, Steffi G. Riedel-Heller, Anders Wimo, Roni Peleg, Kathrin Heser, Michael Blankenburg, K. Blennow, Hanna Leicht, Wei Song, Seigo Fujita, Ping Lei Pan, Tzvi Dwolatzky, Joan Mackell, Bo Liu, Oriol Turró-Garriga, Jian Guo Zhong, Joan Coromina, Nicolas von Ahsen, Edelgard Mösch, Héctor Perkal, Rachelle S. Doody, Bengt Winblad, Anton Forsberg, Dorota Religa, M. Plichart, Martin Scherer, O. Hanon, Wolfgang Maier, A.-S. Rigaud, Yulan Tang, E.P. Moll van Charante, Yijun Sun, Isabel Casas, Margarida Flaqué, Yan Press, Josep Garre-Olmo, Satz Mengensatzproduktion, Yuefei Shen, Ke Chen, J.-E. Månsson, W.A. van Gool, L. Hugonot-Diener, Joan Vilalta-Franch, P. Høgh, Siegfried Weyerer, Natalia Velikiy, Qi Yong Gong, Diogo Costa, Kouzo Takeuchi, N. Bogdanovic, Linda Clare, Druck Reinhardt Druck Basel, Howard Tandeter, and Secundino López-Pousa

Subjects
Psychiatry and Mental health, Optics, business.industry, Cognitive Neuroscience, Geriatrics and Gerontology, business, Geology, Front (military)
Published
2012

10. [Considerable diagnostic variation among memory clinics - is it an issue?]

Author

Moll van Charante EP and Richard E

Subjects
Aged, Dementia diagnosis, Female, Humans, Male, Netherlands, Surveys and Questionnaires, Dementia psychology, Memory Disorders diagnosis
Abstract

A recent survey shows a steady growth in the number of memory clinics in the Netherlands over the last two decades. It appears there is considerable variation in both the organization of care and the type of diagnostic work-up that is provided. Over time, the memory clinic population has also changed; 22% of patients present with subjective memory complaints, a three-fold increase. Although the current dementia guidelines leave much room for individualized diagnostic trajectories, the results suggest a lack of consensus on the indication for the different diagnostic tests. More insight is needed in the causes of variation, before discussing to what extent this variation is acceptable or perhaps even desirable considering the widely differing patient populations. In the meantime, patients and carers deserve a more prominent role in the diagnostic process, to ensure that the quest for a timely diagnosis will go hand in hand with appropriate use of memory clinics.

Published
2019

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