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From mono- and bis-benzimidazolium salts, three new Se–NHC adducts were synthesized using water as a solvent. Single crystals analyses indicated that crystal structures of Se–NHC adducts are stabilized by face-to-face and edge-to-face π–π interactions in the absences of any potential hydrogen bonds donor and acceptor. Benzimidazolium salts and respective Se–NHC adducts were preliminarily screened against human colorectal cell line (HCT 116) where the benzyl substituted benzimidazolium salt and respective Se–NHC adduct showed the far best results among the test compounds. The selected compounds were further studied in detail for pro-apoptotic mechanism of action (Hoest 33342 stain and Rhodamine 123 tests). The tested compounds were found to induce apoptosis via mitochondria pathway.

The aim of this study was to investigate the influence of short-term treatment of high-energy diet after ovulation on ovarian function and metabolic status in ewe. Cycling ewes Ossimi were divided into treatment group (TG; n = 6) and control group (CG; n = 6). After ultrasonographic detection of ovulation (day 0), a high-energy diet (12.55 MJ DE/kg diet; 125% of maintenance) was fed to TG from day 1 to day 4 after ovulation (4 days). The high-energy diet consisted of 850 g concentrate mixture and 150 g alfalfa hay, plus ad libitum access to wheat straw. The CG was offered as maintenance diet (10 MJ DE/kg diet) throughout the experiment. Follicular development was observed ultrasonographically every other day while blood samples were collected daily throughout the experiment for the analysis of glucose, total cholesterol, urea, triglycerides, total proteins, aspartate aminotransferase (AST), alanine transaminase (ALT) and glutamate oxaloacetate transaminase (GOT). Transient feeding of high-energy ration during early luteal phase of estrous cycle significantly influenced the concentration of glucose and some metabolic profiles. Total proteins were greater at first, third and fourth day after ovulation (ovulation is day 0) in TG when compared to CG ewes. Blood glucose concentration was greater in TG than that of CG at days 1, 2, 3 and 4 postovulation. The average number of small follicles (2–2.9 mm) of the first follicular wave after ovulation was greater in TG ewes (23.3 follicles) than that of CG (2.2). There was no difference in the number of medium (3–5 mm) and large sized follicles (>5 mm) between CG and TG ewes. Moreover, the maximum size of large follicles did not differ between CG (5.6 mm) and TG ewes (5.9 mm). In conclusion, high-energy diet may improve number of small follicles and alter energy metabolite during early luteal phase in cycling ewes.

Egyptian cotton straw powder was acid hydrolized in presence of coal tar phenols fraction (b.r. 170–185°C) to give the phenols‐furfural resin. Homopolyepoxy resin was prepared via condensation of epichlorohydrin with phenols‐furfural resin. Similarly copolyepoxy resin was also prepared from epichlorohyhdrin, phenols‐furfural resin and prepared bisphenol A based on coal tar phenols fraction. A study of curing these epoxy resins at 170–185°C with phthalic or maleic anhydride also curing at room temperature with amine was carried out. Also the effect of the addition of kaolin as a filler was investigated to find the optimum condition which allow the cured resin to act as wood adhesive. The obtained results were comparable with those of some commercial adhesives.