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1. Prevalencia de desnutrición e influencia de la suplementación nutricional oral sobre el estado nutricional en ancianos institucionalizados Prevalence of malnutrition and influence of oral nutritional supplementation on nutritional status in institutionalized elderly

Author: F. Pérez Llamas, A. Moregó, M. Tóbaruela, Mª D. García, E. Santo, and S. Zamora
Subjects: Residencias públicas, Personas mayores, Desnutrición, Suplementación nutricional oral, GNRI, Elderly, Public nursing home, Malnutrition, Oral nutritional supplementation, Nutritional diseases. Deficiency diseases, RC620-627
Abstract: Introducción: La suplementación nutricional puede ser una efectiva estrategia para mejorar el estado nutricional y la calidad de vida de ancianos frágiles institucionalizados. Objetivos: Se ha valorado la prevalencia de desnutrición y su relación con el tipo de enfermedad, y la influencia de la suplementación de la dieta con fórmulas orales sobre el estado nutricional en ancianos institucionalizados. Métodos: Se realizaron dos estudios, uno de diseño transversal en el que participaron 31 ancianos, y otro de corte longitudinal con 19 ancianos, residentes en una institución pública para personas mayores de un área urbana de la Región de Murcia (España). Se ha determinado índice de masa corporal (IMC), concentración de albúmina sérica (ALB) e índice de riesgo nutricional geriátrico (GNRI) como marcadores de desnutrición y se ha registrado la enfermedad primaria y secundaria de los participantes. Resultados y discusión: La prevalencia de desnutrición en el colectivo de ancianos institucionalizados es elevada (39%), y especialmente en los residentes más frágiles (50%). La administración de suplementos nutricionales orales con la dieta habitual durante 12 meses ha incrementado significativamente la ALB y el GNRI y no ha tenido efecto sobre el peso corporal e IMC. Estos efectos beneficiosos se han traducido en la reducción en el número de ancianos con alto riesgo nutricional y aumento en el de bajo o nulo riesgo de desnutrición. Conclusión: La administración de suplementos nutricionales orales con la dieta habitual en un colectivo de estas características, es una medida clínica efectiva y justificada en su terapia nutricional.Background: Nutritional supplementation might be an effective strategy for improving the nutritional status and the quality of life of institutionalized fragile elderly. Objectives: The prevalence of malnutrition and its relation with disease, and the influence of dietary supplementation by means of oral formulas on the nutritional status of elderly nursing home residents were assessed. Methods: Two studies were carried out, one a crosssectional survey in 31 subjects and the other a longitudinal-sectional survey in 19 subjects, both groups living in a public nursing home in the city of Murcia (SE Spain). Body mass index (BMI), serum albumin concentration (ALB) and geriatric nutritional risk index (GNRI) were assessed as markers of potential malnutrition. Illnesses were ascertained from medical records. Results and discussion: The prevalence of malnutrition of the total collective was high (39%), and especially in the fragile subjects (50%). The administration of oral nutritional supplements in the usual diet for 12 months significantly increased ALB and GNRI, and had no effect on body weigh and BMI. Jointly, these effects decreased the in the number of subjects at high nutritional risk and increased the number of subjects with a low or zero risk of malnutrition. Conclusion: The administration of oral nutritional supplements in the usual diet of this elderly collective is an effective clinical strategy in nutritional therapy.
Published: 2011

2. Prevalence of virulence factors in Escherichia coli strains isolated from the genital tract of healthy cows Prevalência de fatores de virulência em cepas de Escherichia coli isoladas do trato genital de vacas saudáveis

Author: D. Resende, E. Santo, C. Macedo, and J.M. Marin
Subjects: vaca, Escherichia coli, trato genital, fatores de virulência, cow, genital tract, virulence factors, Animal culture, SF1-1100
Abstract: The prevalence of virulence genes expressing fimbriae, production of hemolysin, colicin and aerobactin, was determined in Escherichia coli isolates from healthy cow’s genital tract not showing clinical signs of infection. The presence of fimbriae expression genes (pap, sfa, afa) was assayed using specific primers in a polymerase chain reaction; none were detected in any of the isolates. Yet, a prevalence of 90.4%, 69.8%, and 28.5% of virulence factors for colicin, hemolysin and aerobactin respectively, was detected in the isolates. Analysis of the bacterial pathogenicity of isolates from the bovine genital tract may contribute towards the understanding of E. coli behavior.Determinou-se a prevalência dos genes de virulência expressando fimbrias, produção de hemolisina, colicina e aerobactina em cepas de Escherichia coli obtidas do trato genital de vacas saudáveis que não apresentam sinais clínicos indicativos de infecção. A presença dos genes responsáveis pela expressão de fimbrias (pap, sfa, afa) foi avaliada através de reação em cadeia da polimerase utilizando primers especificos para cada um dos genes, nenhum deles foi detectado em qualquer uma das cepas isoladas. A prevalência dos fatores de virulência foi de 90,4%, 69,8%, 28,5% para colicina, hemolisina e aerobactina, respectivamente. A análise da patogenicidade das cepas do trato genital pode contribuir para o entendimento do comportamento das cepas de E. coli.
Published: 2007
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3. Occurrence of toxigenic Escherichia coli in raw milk cheese in Brazil Ocorrência de Escherichia coli toxigênica em queijo-de-minas frescal no Brasil

Author: B.R. Paneto, R.P. Schocken-Iturrino, C. Macedo, E. Santo, and J.M. Marin
Subjects: Escherichia coli, queijo, VTEC, ETEC, resistência antimicrobiana, cheese, antimicrobial resistance, Animal culture, SF1-1100
Abstract: The occurrence of toxigenic Escherichia coli in raw milk cheese was surveyed in Middle Western Brazil. Fifty samples of cheese from different supermarkets were analyzed for E.coli. The isolates were serotyped and screened for the presence of verotoxigenic E. coli (VTEC) and enterotoxigenic E. coli (ETEC) by Polymerase Chain Reaction (PCR). The susceptibility to thirteen antimicrobial agents was evaluated by the disk diffusion method. E.coli were recovered from 48 (96.0%) of the samples. The serogroups identified were O125 (6.0%), O111 (4.0%), O55 (2.0%) and O119 (2.0%). Three (6.0%) and 1(2.0%) of the E.coli isolates were VTEC and ETEC, respectively. Most frequent resistance was observed to the following antimicrobials: cephalothin (60.0%), nalidixic acid (40.0%), doxycyclin (33.0%), tetracycline (31.0%) and ampicillin (29.0%).Pesquisou-se a ocorrência de Escherichia coli toxigênica, em queijo produzido com leite não pasteurizado, na Região Centro Oeste do Brazil. Foram utilizados 50 queijos adquiridos em diferentes supermercados. As amostras isoladas foram classificadas por sorogrupo, avaliadas em relação à sensibilidade para 13 agentes antimicrobianos e submetidas à reação em cadeia da polimerase para a presença de genes característicos de E. coli verotoxigênica (VTEC) e enterotoxigênica (ETEC). E. coli foi recuperada em 48(96,0%) dos queijos. Foram identificados os sorogrupos O125 (6,0%), O111 (4,0%), O55 (2,0%) e O119 (2,0%). Três (6,0%) amostras de E. coli foram classificadas como VTEC e uma (2,0%) como ETEC. Os maiores índices de resistência foram verificados para: cefalotina (60,0%), ácido nalidíxico (40,0%), doxiciclina (33,0%), tetraciclina (31,0%) e ampicilina (29,0%).
Published: 2007
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4. Ultrahigh Energy Neutrinos at the Pierre Auger Observatory

Author: P. Abreu, M. Aglietta, M. Ahlers, E. J. Ahn, I. F. M. Albuquerque, D. Allard, I. Allekotte, J. Allen, P. Allison, A. Almela, J. Alvarez Castillo, J. Alvarez-Muñiz, R. Alves Batista, M. Ambrosio, A. Aminaei, L. Anchordoqui, S. Andringa, T. Antičić, C. Aramo, E. Arganda, F. Arqueros, H. Asorey, P. Assis, J. Aublin, M. Ave, M. Avenier, G. Avila, T. Bäcker, A. M. Badescu, M. Balzer, K. B. Barber, A. F. Barbosa, R. Bardenet, S. L. C. Barroso, B. Baughman, J. Bäuml, J. J. Beatty, B. R. Becker, K. H. Becker, A. Bellétoile, J. A. Bellido, S. BenZvi, C. Berat, X. Bertou, P. L. Biermann, P. Billoir, F. Blanco, M. Blanco, C. Bleve, H. Blümer, M. Boháčová, D. Boncioli, C. Bonifazi, R. Bonino, N. Borodai, J. Brack, I. Brancus, P. Brogueira, W. C. Brown, R. Bruijn, P. Buchholz, A. Bueno, R. E. Burton, K. S. Caballero-Mora, B. Caccianiga, L. Caramete, R. Caruso, A. Castellina, O. Catalano, G. Cataldi, L. Cazon, R. Cester, J. Chauvin, S. H. Cheng, A. Chiavassa, J. A. Chinellato, J. Chirinos Diaz, J. Chudoba, M. Cilmo, R. W. Clay, M. R. Coluccia, R. Conceição, F. Contreras, H. Cook, M. J. Cooper, J. Coppens, A. Cordier, S. Coutu, C. E. Covault, A. Creusot, A. Criss, J. Cronin, A. Curutiu, S. Dagoret-Campagne, R. Dallier, B. Daniel, S. Dasso, K. Daumiller, B. R. Dawson, R. M. de Almeida, M. De Domenico, C. De Donato, S. J. de Jong, G. De La Vega, W. J. M. de Mello Junior, J. R. T. de Mello Neto, I. De Mitri, V. de Souza, K. D. de Vries, L. del Peral, M. del Río, O. Deligny, H. Dembinski, N. Dhital, C. Di Giulio, M. L. Díaz Castro, P. N. Diep, F. Diogo, C. Dobrigkeit, W. Docters, J. C. D'Olivo, P. N. Dong, A. Dorofeev, J. C. dos Anjos, M. T. Dova, D. D'Urso, I. Dutan, J. Ebr, R. Engel, M. Erdmann, C. O. Escobar, J. Espadanal, A. Etchegoyen, P. Facal San Luis, H. Falcke, G. Farrar, A. C. Fauth, N. Fazzini, A. P. Ferguson, B. Fick, A. Filevich, A. Filipčič, S. Fliescher, C. E. Fracchiolla, E. D. Fraenkel, O. Fratu, U. Fröhlich, B. Fuchs, R. Gaior, R. F. Gamarra, S. Gambetta, B. García, S. T. Garcia Roca, D. Garcia-Gamez, D. Garcia-Pinto, A. Gascon Bravo, H. Gemmeke, P. L. Ghia, M. Giller, J. Gitto, H. Glass, M. S. Gold, G. Golup, F. Gomez Albarracin, M. Gómez Berisso, P. F. Gómez Vitale, P. Gonçalves, J. G. Gonzalez, B. Gookin, A. Gorgi, P. Gouffon, E. Grashorn, S. Grebe, N. Griffith, M. Grigat, A. F. Grillo, Y. Guardincerri, F. Guarino, G. P. Guedes, P. Hansen, D. Harari, T. A. Harrison, J. L. Harton, A. Haungs, T. Hebbeker, D. Heck, A. E. Herve, C. Hojvat, N. Hollon, V. C. Holmes, P. Homola, J. R. Hörandel, P. Horvath, M. Hrabovský, D. Huber, T. Huege, A. Insolia, F. Ionita, A. Italiano, C. Jarne, S. Jiraskova, M. Josebachuili, K. Kadija, K. H. Kampert, P. Karhan, P. Kasper, I. Katkov, B. Kégl, B. Keilhauer, A. Keivani, J. L. Kelley, E. Kemp, R. M. Kieckhafer, H. O. Klages, M. Kleifges, J. Kleinfeller, J. Knapp, D.-H. Koang, K. Kotera, N. Krohm, O. Krömer, D. Kruppke-Hansen, F. Kuehn, D. Kuempel, J. K. Kulbartz, N. Kunka, G. La Rosa, C. Lachaud, D. LaHurd, L. Latronico, R. Lauer, P. Lautridou, S. Le Coz, M. S. A. B. Leão, D. Lebrun, P. Lebrun, M. A. Leigui de Oliveira, A. Letessier-Selvon, I. Lhenry-Yvon, K. Link, R. López, A. Lopez Agüera, K. Louedec, J. Lozano Bahilo, L. Lu, A. Lucero, M. Ludwig, H. Lyberis, M. C. Maccarone, C. Macolino, S. Maldera, D. Mandat, P. Mantsch, A. G. Mariazzi, J. Marin, V. Marin, I. C. Maris, H. R. Marquez Falcon, G. Marsella, D. Martello, L. Martin, H. Martinez, O. Martínez Bravo, H. J. Mathes, J. Matthews, J. A. J. Matthews, G. Matthiae, D. Maurel, D. Maurizio, P. O. Mazur, G. Medina-Tanco, M. Melissas, D. Melo, E. Menichetti, A. Menshikov, P. Mertsch, C. Meurer, S. Mićanović, M. I. Micheletti, I. A. Minaya, L. Miramonti, L. Molina-Bueno, S. Mollerach, M. Monasor, D. Monnier Ragaigne, F. Montanet, B. Morales, C. Morello, E. Moreno, J. C. Moreno, M. Mostafá, C. A. Moura, M. A. Muller, G. Müller, M. Münchmeyer, R. Mussa, G. Navarra, J. L. Navarro, S. Navas, P. Necesal, L. Nellen, A. Nelles, J. Neuser, P. T. Nhung, M. Niechciol, L. Niemietz, N. Nierstenhoefer, D. Nitz, D. Nosek, L. Nožka, J. Oehlschläger, A. Olinto, M. Ortiz, N. Pacheco, D. Pakk Selmi-Dei, M. Palatka, J. Pallotta, N. Palmieri, G. Parente, E. Parizot, A. Parra, S. Pastor, T. Paul, M. Pech, J. Pękala, R. Pelayo, I. M. Pepe, L. Perrone, R. Pesce, E. Petermann, S. Petrera, A. Petrolini, Y. Petrov, C. Pfendner, R. Piegaia, T. Pierog, P. Pieroni, M. Pimenta, V. Pirronello, M. Platino, M. Plum, V. H. Ponce, M. Pontz, A. Porcelli, P. Privitera, M. Prouza, E. J. Quel, S. Querchfeld, J. Rautenberg, O. Ravel, D. Ravignani, B. Revenu, J. Ridky, S. Riggi, M. Risse, P. Ristori, H. Rivera, V. Rizi, J. Roberts, W. Rodrigues de Carvalho, G. Rodriguez, I. Rodriguez Cabo, J. Rodriguez Martino, J. Rodriguez Rojo, M. D. Rodríguez-Frías, G. Ros, J. Rosado, T. Rossler, M. Roth, B. Rouillé-d'Orfeuil, E. Roulet, A. C. Rovero, C. Rühle, A. Saftoiu, F. Salamida, H. Salazar, F. Salesa Greus, G. Salina, F. Sánchez, C. E. Santo, E. Santos, E. M. Santos, F. Sarazin, B. Sarkar, S. Sarkar, R. Sato, N. Scharf, V. Scherini, H. Schieler, P. Schiffer, A. Schmidt, O. Scholten, H. Schoorlemmer, J. Schovancova, P. Schovánek, F. Schröder, S. Schulte, D. Schuster, S. J. Sciutto, M. Scuderi, A. Segreto, M. Settimo, A. Shadkam, R. C. Shellard, I. Sidelnik, G. Sigl, O. Sima, A. Śmiałkowski, R. Šmída, G. R. Snow, P. Sommers, J. Sorokin, H. Spinka, R. Squartini, Y. N. Srivastava, S. Stanic, J. Stapleton, J. Stasielak, M. Stephan, A. Stutz, F. Suarez, T. Suomijärvi, A. D. Supanitsky, T. Šuša, M. S. Sutherland, J. Swain, Z. Szadkowski, M. Szuba, A. Tapia, M. Tartare, O. Taşcău, R. Tcaciuc, N. T. Thao, D. Thomas, J. Tiffenberg, C. Timmermans, W. Tkaczyk, C. J. Todero Peixoto, G. Toma, L. Tomankova, B. Tomé, A. Tonachini, P. Travnicek, D. B. Tridapalli, G. Tristram, E. Trovato, M. Tueros, R. Ulrich, M. Unger, M. Urban, J. F. Valdés Galicia, I. Valiño, L. Valore, A. M. van den Berg, E. Varela, B. Vargas Cárdenas, J. R. Vázquez, R. A. Vázquez, D. Veberič, V. Verzi, J. Vicha, M. Videla, L. Villaseñor, H. Wahlberg, P. Wahrlich, O. Wainberg, D. Walz, A. A. Watson, M. Weber, K. Weidenhaupt, A. Weindl, F. Werner, S. Westerhoff, B. J. Whelan, A. Widom, G. Wieczorek, L. Wiencke, B. Wilczyñska, H. Wilczyñski, M. Will, C. Williams, T. Winchen, M. Wommer, B. Wundheiler, T. Yamamoto, T. Yapici, P. Younk, G. Yuan, A. Yushkov, B. Zamorano Garcia, E. Zas, D. Zavrtanik, M. Zavrtanik, I. Zaw, A. Zepeda, Y. Zhu, M. Zimbres Silva, and M. Ziolkowski
Subjects: Physics, QC1-999
Abstract: The observation of ultrahigh energy neutrinos (UHEνs) has become a priority in experimental astroparticle physics. UHEνs can be detected with a variety of techniques. In particular, neutrinos can interact in the atmosphere (downward-going ν) or in the Earth crust (Earth-skimming ν), producing air showers that can be observed with arrays of detectors at the ground. With the surface detector array of the Pierre Auger Observatory we can detect these types of cascades. The distinguishing signature for neutrino events is the presence of very inclined showers produced close to the ground (i.e., after having traversed a large amount of atmosphere). In this work we review the procedure and criteria established to search for UHEνs in the data collected with the ground array of the Pierre Auger Observatory. This includes Earth-skimming as well as downward-going neutrinos. No neutrino candidates have been found, which allows us to place competitive limits to the diffuse flux of UHEνs in the EeV range and above.
Published: 2013
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5. Internet of Things: A Survey on Communication Protocol Security.

Author: Walter E. Santo, Ricardo J. P. de B. Salgueiro, Reneilson Santos, Danilo Lima Souza, Admilson Lima Ribeiro, and Edward D. Moreno
Published: 2018
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6. CORRELAÇÕES ENTRE A CLASSIFICAÇÃO FUNCIONAL E O DESEMPENHO MOTOR DE JOGADORES DE BASQUETEBOL DE CADEIRAS DE RODAS EXPERIENTES

Author: Williane de Sales Tôrres, José Marcos M. Oliveira, Clara K. M. A. da Silva, Diego Francisco da Silva, Rudá G. E. Santo, and Saulo F. M. Oliveira
Subjects: General Medicine
Abstract: O objetivo do estudo é verificar a correlação entre a classificação funcional (CF) e o nível de desempenho motor de atletas experientes de basquete em cadeira de rodas (BCR). Através de um estudo observacional transversal, foram recrutados 10 jogadores de BCR, para realizar o teste de capacidade aeróbica, teste de velocidade, e o teste de agilidade com e sem bola. Através da análise de associação por meio do teste de correlação de Spearman e adotou-se um p de pode-se observar que houve correlação inversa forte, com nível de significância fixado em 5% (p
Published: 2023

7. Os fatores determinantes e as complicações oriundas do crescimento fetal restrito

Author: Tharín Marques Veiga, Taynara Rodrigues Da Cruz, Roni Simão, Eduarda Takatsu, Luis Henrique Fagundes Almeida, Isabella Maria Figueiredo Tuma Da Ponte, Marlene Alencar Da Silva, Catarinne Pacelli Benício de Carvalho, Melina Stefania Grings, Geybssom Tarcio Evaristo De Sousa, Bárbara Vitória Marinho Moreira e Santo, Eduardo Henrique Sarmento Bastos, Bibiana Aparecida Pereira Machado, Josielen Alexandria Serra da Silva, Marcos Antonio Pitaluga Cunha, Rafael Leituga de Carvalho Cavalcante, Dernevan Rodrigues Dos Santos, Deivam São Leão Leite, Ketlen Michele Leite Rio Branco, Michele Leite Rio Branco, Ana Cláudia Rossi Costa, Jorge da Silva Segundo, Paulo Henrique Mai, Thiago Nominato Marques, James Lucas Marques Dourado, and Jorge Eduardo Peixoto Pereira
Subjects: Marketing, Pharmacology, Organizational Behavior and Human Resource Management, Strategy and Management, Drug Discovery, Pharmaceutical Science
Abstract: O feto portador de restrição do crescimento fetal intra-uterino evolui sem alcançar o seu potencial genético de crescimento. Destacando, que o Crescimento Intra-Uterino Restrito (CIUR) condiz a um complexo heterogêneo, caracterizado pela maioria ser de fetos biologicamente pequenos, mas não se encaixam na condição patológica, a qual urge por monitoramento. Neste contexto, pode estar ou não relacionado a inúmeras doenças a qual necessitam ser diagnosticadas. O objetivo deste estudo foi analisar os fatores relacionados na etiologia e das complicações da restrição do crescimento intra-uterino. As informações existentes na literatura evidenciam a existência de vários desencadeantes nesta ocorrência, a qual abordam a associação de fatores maternos, placentários e fetais. Os distintos grupos possivelmente podem coexistir de modo simultâneo, sendo parte destes passíveis de prevenção.
Published: 2022

8. Denaturing mass photometry for straightforward optimization of protein-protein cross-linking reactions at single-molecule level

Author: Hugo Gizardin-Fredon, Paulo E. Santo, Marie-Eve Chagot, Bruno Charpentier, Tiago M. Bandeiras, Xavier Manival, Oscar Hernandez-Alba, and Sarah Cianferani
Abstract: Mass photometry (MP) is a versatile, fast and low sample-consuming biophysical technique that gained interest in structural biology to study noncovalent assemblies in native conditions. We report here on a novel method to perform MP analysis in denaturing conditions (dMP) and its application for fast, accurate and straightforward optimization of chemical reactions in cross-linking mass spectrometry (XL-MS) workflows. dMP consists in a robust 2-step protocol that ensures 95% of irreversible denaturation within only 5 min. The proposed single-molecule method clearly overcomes the limitations and outperforms gold standard SDS-PAGE, as illustrated on several biological complexes. dMP provides an unprecedented and unmatched in-solution quantification of all coexisting XL species, including sub-complexes and non-specific XL aggregates, along with identification of significantly higher numbers of XL dipeptides in MS. We anticipate single-molecule dMP to be a high-impact game-changer for the XL-MS community with the potential to leverage the quality and reliability of XL-MS datasets.
Published: 2023

9. Supplementary Methods from FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

Author: Ellen M. Westerhout, Rogier Versteeg, Jan Koster, Peter V. Sluis, Peter Stroeken, and Evan E. Santo
Abstract: Supplementary Methods PDF file - 114K, Includes Lentiviral constructs, Western blotting & Cell fractionation, Luciferase constructs & reporter assay, Cell Viability Assay, Microarray profiling, and TFBS enrichment analysis. Also includes Supplementary References
Published: 2023

10. Supplementary Figure and Table Legends from FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

Author: Ellen M. Westerhout, Rogier Versteeg, Jan Koster, Peter V. Sluis, Peter Stroeken, and Evan E. Santo
Abstract: Supplementary Figure and Table Legends PDF file - 63K, Legend for Supplementary Figures S1-S5 and Supplementary Table S1
Published: 2023

11. Supplementary Table S1 from FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

Author: Ellen M. Westerhout, Rogier Versteeg, Jan Koster, Peter V. Sluis, Peter Stroeken, and Evan E. Santo
Abstract: Supplementary Table S1 XLS file - 186K, Genes regulated in the SY5Y microarray experiments
Published: 2023

12. Data from FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma

Author: Ellen M. Westerhout, Rogier Versteeg, Jan Koster, Peter V. Sluis, Peter Stroeken, and Evan E. Santo
Abstract: Neuroblastoma is a pediatric tumor of the peripheral sympathetic nervous system with a highly variable prognosis. Activation of the phosphoinositide 3-kinase (PI3K)/AKT pathway in neuroblastoma is correlated with poor patient prognosis, but the precise downstream effectors mediating this effect have not been determined. Here we identify the forkhead transcription factor FOXO3a as a key target of the PI3K/AKT pathway in neuroblastoma. FOXO3a expression was elevated in low-stage neuroblastoma tumors and normal embryonal neuroblasts, but reduced in late-stage neuroblastoma. Inactivation of FOXO3a by AKT was essential for neuroblastoma cell survival. Treatment of neuroblastoma cells with the dual PI3K/mTOR inhibitor PI-103 activated FOXO3a and triggered apoptosis. This effect was rescued by FOXO3a silencing. Conversely, apoptosis induced by PI-103 or the AKT inhibitor MK-2206 was potentiated by FOXO3a overexpression. Furthermore, levels of total or phosphorylated FOXO3a correlated closely with apoptotic sensitivity to MK-2206. In clinical specimens, there was an inverse relationship between gene expression signatures regulated by PI3K signaling and FOXO3a transcriptional activity. Moreover, high PI3K activity and low FOXO3a activity were each associated with an extremely poor prognosis. Our work indicates that expression of FOXO3a and its targets offer useful prognostic markers as well as biomarkers for PI3K/AKT inhibitor efficacy in neuroblastoma. Cancer Res; 73(7); 2189–98. ©2013 AACR.
Published: 2023

13. Effects of a high-fat diet on the bone structure of Wistar rats: a systematic review

Author: Rafael T Silva, Luciana J D Ferreira, Ana P A Macêdo, Lucimeire S Santos, Djane A E Santo, Gabriele S Codeiro, Marcia U Pereira, Ingrid O R Medeiros, Carlos A S da Costa, and Jairza M Barreto Medeiros
Subjects: Nutrition and Dietetics, Medicine (miscellaneous)
Abstract: ContextSaturated fats found in diets known as high-fat, cafeteria, or Western diets appear to have a negative effect on bone structure; however, few studies have focused on investigating this association, and the data available in the literature remain controversial.ObjectiveThe aim of the current review was to investigate the effects of a high-fat dietary intake on the bone structure of Wistar rats.Data SourcesA search for articles was carried out in the Pubmed/MEDLINE, Web of Science, Embase, and Scopus databases.Data ExtractionIn total, 447 articles were found in the initial search; 5 articles were included in the systematic review, after application of the exclusion criteria.Data AnalysisThe review was guided by the PICOS strategy and based on the PRISMA protocol for animal reviews.ConclusionHigh-fat diets appear to affect bone structure of Wistar rats. Diet composition and exposure time are the factors determining the strength of the effect.
Published: 2023

14. Moulins

Author: Carolina E. Santo
Subjects: Visual Arts and Performing Arts, Architecture
Published: 2022

15. Observation of muonic Dalitz decays of chib mesons and precise spectroscopy of hidden-beauty states

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, R. Ataíde Da Silva, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, L. Balzani, H. Bao, J. Baptista de Souza Leite, C. Barbero Pretel, M. Barbetti, I. R. Barbosa, R. J. Barlow, M. Barnyakov, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, J. M. Basels, S. Bashir, G. Bassi, B. Batsukh, P. B. Battista, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, N. B. Behling, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, A. Bordelius, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, M. Bovill, T. J. V. Bowcock, A. Boyer, C. Bozzi, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, A. C. Caillet, R. Calabrese, S. Calderon Ramirez, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, P. Camargo Magalhaes, J. I. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. Carcedo Salgado, R. Cardinale, A. Cardini, P. Carniti, L. Carus, A. Casais Vidal, R. Caspary, G. Casse, J. Castro Godinez, M. Cattaneo, G. Cavallero, V. Cavallini, S. Celani, D. Cervenkov, S. Cesare, A. J. Chadwick, I. Chahrour, M. Charles, Ph. Charpentier, E. Chatzianagnostou, M. Chefdeville, C. Chen, S. Chen, Z. Chen, A. Chernov, S. Chernyshenko, X. Chiotopoulos, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. Cifra, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Cocha Toapaxi, V. Coco, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, M. C. Colonna, A. Comerma-Montells, L. Congedo, A. Contu, N. Cooke, I. Corredoira, A. Correia, G. Corti, J. J. Cottee Meldrum, B. Couturier, D. C. Craik, M. Cruz Torres, E. Curras Rivera, R. Currie, C. L. Da Silva, S. Dadabaev, L. Dai, X. Dai, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, J. Daniel, A. Danilina, P. d’Argent, A. Davidson, J. E. Davies, A. Davis, O. De Aguiar Francisco, C. De Angelis, F. De Benedetti, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, S. Dekkers, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. Feng, M. Feo, A. Fernandez Casani, M. Fernandez Gomez, A. D. Fernez, F. Ferrari, F. Ferreira Rodrigues, M. Ferrillo, M. Ferro-Luzzi, S. Filippov, R. A. Fini, M. Fiorini, M. Firlej, K. L. Fischer, D. S. Fitzgerald, C. Fitzpatrick, T. Fiutowski, F. Fleuret, M. Fontana, L. F. Foreman, R. Forty, D. Foulds-Holt, V. Franco Lima, M. Franco Sevilla, M. Frank, E. Franzoso, G. Frau, C. Frei, D. A. Friday, J. Fu, Q. Fuehring, Y. Fujii, T. Fulghesu, E. Gabriel, G. Galati, M. D. Galati, A. Gallas Torreira, D. Galli, S. Gambetta, M. Gandelman, P. Gandini, B. Ganie, H. Gao, R. Gao, T. Q. Gao, Y. Gao, M. Garau, L. M. Garcia Martin, P. Garcia Moreno, J. García Pardiñas, K. G. Garg, L. Garrido, C. Gaspar, R. E. Geertsema, L. L. Gerken, E. Gersabeck, M. Gersabeck, T. Gershon, S. G. Ghizzo, Z. Ghorbanimoghaddam, L. Giambastiani, F. I. Giasemis, V. Gibson, H. K. Giemza, A. L. Gilman, M. Giovannetti, A. Gioventù, L. Girardey, P. Gironella Gironell, C. Giugliano, M. A. Giza, E. L. Gkougkousis, F. C. Glaser, V. V. Gligorov, C. Göbel, E. Golobardes, D. Golubkov, A. Golutvin, A. Gomes, S. Gomez Fernandez, F. Goncalves Abrantes, M. Goncerz, G. Gong, J. A. Gooding, I. V. Gorelov, C. Gotti, J. P. Grabowski, L. A. Granado Cardoso, E. Graugés, E. Graverini, L. Grazette, G. Graziani, A. T. Grecu, L. M. Greeven, N. A. Grieser, L. Grillo, S. Gromov, C. Gu, M. Guarise, L. Guerry, M. Guittiere, V. Guliaeva, P. A. Günther, A.-K. Guseinov, E. Gushchin, Y. Guz, T. Gys, K. Habermann, T. Hadavizadeh, C. Hadjivasiliou, G. Haefeli, C. Haen, J. Haimberger, M. Hajheidari, G. H. Hallett, M. M. Halvorsen, P. M. Hamilton, J. Hammerich, Q. Han, X. Han, S. Hansmann-Menzemer, L. Hao, N. Harnew, M. Hartmann, S. Hashmi, J. He, F. Hemmer, C. Henderson, R. D. L. Henderson, A. M. Hennequin, K. Hennessy, L. Henry, J. Herd, P. Herrero Gascon, J. Heuel, A. Hicheur, G. Hijano Mendizabal, D. Hill, S. E. Hollitt, J. Horswill, R. Hou, Y. Hou, N. Howarth, J. Hu, W. Hu, X. Hu, W. Huang, W. Hulsbergen, R. J. Hunter, M. Hushchyn, D. Hutchcroft, M. Idzik, D. Ilin, P. Ilten, A. Inglessi, A. Iniukhin, A. Ishteev, K. Ivshin, R. Jacobsson, H. Jage, S. J. Jaimes Elles, S. Jakobsen, E. Jans, B. K. Jashal, A. Jawahery, V. Jevtic, E. Jiang, X. Jiang, Y. Jiang, Y. J. Jiang, M. John, A. John Rubesh Rajan, D. Johnson, C. R. Jones, T. P. Jones, S. Joshi, B. Jost, J. Juan Castella, N. Jurik, I. Juszczak, D. Kaminaris, S. Kandybei, M. Kane, Y. Kang, C. Kar, M. Karacson, D. Karpenkov, A. Kauniskangas, J. W. Kautz, M. K. Kazanecki, F. Keizer, M. Kenzie, T. Ketel, B. Khanji, A. Kharisova, S. Kholodenko, G. Khreich, T. Kirn, V. S. Kirsebom, O. Kitouni, S. Klaver, N. Kleijne, K. Klimaszewski, M. R. Kmiec, S. Koliiev, L. Kolk, A. Konoplyannikov, P. Kopciewicz, P. Koppenburg, M. Korolev, I. Kostiuk, O. Kot, S. Kotriakhova, A. Kozachuk, P. Kravchenko, L. Kravchuk, M. Kreps, P. Krokovny, W. Krupa, W. Krzemien, O. K. Kshyvanskyi, S. Kubis, M. Kucharczyk, V. Kudryavtsev, E. Kulikova, A. Kupsc, B. K. Kutsenko, D. Lacarrere, P. Laguarta Gonzalez, A. Lai, A. Lampis, D. Lancierini, C. Landesa Gomez, J. J. Lane, R. Lane, G. Lanfranchi, C. Langenbruch, J. Langer, O. Lantwin, T. Latham, F. Lazzari, C. Lazzeroni, R. Le Gac, H. Lee, R. Lefèvre, A. Leflat, S. Legotin, M. Lehuraux, E. Lemos Cid, O. Leroy, T. Lesiak, E. Lesser, B. Leverington, A. Li, C. Li, H. Li, K. Li, L. Li, M. Li, P. Li, P.-R. Li, Q. Li, S. Li, T. Li, Y. Li, Z. Lian, X. Liang, S. Libralon, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, K. Liu, S. Liu, W. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, Q. Lu, C. Lucarelli, D. Lucchesi, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. J. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, E. Mariani, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, L. Martel, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. Massafferri, R. Matev, A. Mathad, V. Matiunin, C. Matteuzzi, K. R. Mattioli, A. Mauri, E. Maurice, J. Mauricio, P. Mayencourt, J. Mazorra de Cos, M. Mazurek, M. McCann, L. Mcconnell, T. H. McGrath, N. T. McHugh, A. McNab, R. McNulty, B. Meadows, G. Meier, D. Melnychuk, F. M. Meng, M. Merk, A. Merli, L. Meyer Garcia, D. Miao, H. Miao, M. Mikhasenko, D. A. Milanes, A. Minotti, E. Minucci, T. Miralles, B. Mitreska, D. S. Mitzel, A. Modak, R. A. Mohammed, R. D. Moise, S. Mokhnenko, E. F. Molina Cardenas, T. Mombächer, M. Monk, S. Monteil, A. Morcillo Gomez, G. Morello, M. J. Morello, M. P. Morgenthaler, J. Moron, A. B. Morris, A. G. Morris, R. Mountain, H. Mu, Z. M. Mu, E. Muhammad, F. Muheim, M. Mulder, K. Müller, F. Muñoz-Rojas, R. Murta, P. Naik, T. Nakada, R. Nandakumar, T. Nanut, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, P. Neustroev, J. Nicolini, D. Nicotra, E. M. Niel, N. Nikitin, P. Nogarolli, P. Nogga, C. Normand, J. Novoa Fernandez, G. Nowak, C. Nunez, H. N. Nur, A. Oblakowska-Mucha, V. Obraztsov, T. Oeser, S. Okamura, A. Okhotnikov, O. Okhrimenko, R. Oldeman, F. Oliva, M. Olocco, C. J. G. Onderwater, R. H. O’Neil, D. Osthues, J. M. Otalora Goicochea, P. Owen, A. Oyanguren, O. Ozcelik, F. Paciolla, A. Padee, K. O. Padeken, B. Pagare, P. R. Pais, T. Pajero, A. Palano, M. Palutan, G. Panshin, L. Paolucci, A. Papanestis, M. Pappagallo, L. L. Pappalardo, C. Pappenheimer, C. Parkes, B. Passalacqua, G. Passaleva, D. Passaro, A. Pastore, M. Patel, J. Patoc, C. Patrignani, A. Paul, C. J. Pawley, A. Pellegrino, J. Peng, M. Pepe Altarelli, S. Perazzini, D. Pereima, H. Pereira Da Costa, A. Pereiro Castro, P. Perret, A. Perro, K. Petridis, A. Petrolini, J. P. Pfaller, H. Pham, L. Pica, M. Piccini, L. Piccolo, B. Pietrzyk, G. Pietrzyk, D. Pinci, F. Pisani, M. Pizzichemi, V. Placinta, M. Plo Casasus, T. Poeschl, F. Polci, M. Poli Lener, A. Poluektov, N. Polukhina, I. Polyakov, E. Polycarpo, S. Ponce, D. Popov, S. Poslavskii, K. Prasanth, C. Prouve, D. Provenzano, V. Pugatch, G. Punzi, S. Qasim, Q. Q. Qian, W. Qian, N. Qin, S. Qu, R. Quagliani, R. I. Rabadan Trejo, J. H. Rademacker, M. Rama, M. Ramírez García, V. Ramos De Oliveira, M. Ramos Pernas, M. S. Rangel, F. Ratnikov, G. Raven, M. Rebollo De Miguel, F. Redi, J. Reich, F. Reiss, Z. Ren, P. K. Resmi, R. Ribatti, G. R. Ricart, D. Riccardi, S. Ricciardi, K. Richardson, M. Richardson-Slipper, K. Rinnert, P. Robbe, G. Robertson, E. Rodrigues, E. Rodriguez Fernandez, J. A. Rodriguez Lopez, E. Rodriguez Rodriguez, J. Roensch, A. Rogachev, A. Rogovskiy, D. L. Rolf, P. Roloff, V. Romanovskiy, M. Romero Lamas, A. Romero Vidal, G. Romolini, F. Ronchetti, T. Rong, M. Rotondo, S. R. Roy, M. S. Rudolph, M. Ruiz Diaz, R. A. Ruiz Fernandez, J. Ruiz Vidal, A. Ryzhikov, J. Ryzka, J. J. Saavedra-Arias, J. J. Saborido Silva, R. Sadek, N. Sagidova, D. Sahoo, N. Sahoo, B. Saitta, M. Salomoni, I. Sanderswood, R. Santacesaria, C. Santamarina Rios, M. Santimaria, L. Santoro, E. Santovetti, A. Saputi, D. Saranin, A. Sarnatskiy, G. Sarpis, M. Sarpis, C. Satriano, A. Satta, M. Saur, D. Savrina, H. Sazak, L. G. Scantlebury Smead, A. Scarabotto, S. Schael, S. Scherl, M. Schiller, H. Schindler, M. Schmelling, B. Schmidt, S. Schmitt, H. Schmitz, O. Schneider, A. Schopper, N. Schulte, S. Schulte, M. H. Schune, R. Schwemmer, G. Schwering, B. Sciascia, A. Sciuccati, S. Sellam, A. Semennikov, T. Senger, M. Senghi Soares, A. Sergi, N. Serra, L. Sestini, A. Seuthe, Y. Shang, D. M. Shangase, M. Shapkin, R. S. Sharma, I. Shchemerov, L. Shchutska, T. Shears, L. Shekhtman, Z. Shen, S. Sheng, V. Shevchenko, B. Shi, Q. Shi, Y. Shimizu, E. Shmanin, R. Shorkin, J. D. Shupperd, R. Silva Coutinho, G. Simi, S. Simone, N. Skidmore, T. Skwarnicki, M. W. Slater, J. C. Smallwood, E. Smith, K. Smith, M. Smith, A. Snoch, L. Soares Lavra, M. D. Sokoloff, F. J. P. Soler, A. Solomin, A. Solovev, I. Solovyev, R. Song, Y. Song, Y. S. Song, F. L. Souza De Almeida, B. Souza De Paula, E. Spadaro Norella, E. Spedicato, J. G. Speer, E. Spiridenkov, P. Spradlin, V. Sriskaran, F. Stagni, M. Stahl, S. Stahl, S. Stanislaus, E. N. Stein, O. Steinkamp, O. Stenyakin, H. Stevens, D. Strekalina, Y. Su, F. Suljik, J. Sun, L. Sun, Y. Sun, D. Sundfeld, W. Sutcliffe, P. N. Swallow, K. Swientek, F. Swystun, A. Szabelski, T. Szumlak, Y. Tan, M. D. Tat, A. Terentev, F. Terzuoli, F. Teubert, E. Thomas, D. J. D. Thompson, H. Tilquin, V. Tisserand, S. T’Jampens, M. Tobin, L. Tomassetti, G. Tonani, X. Tong, D. Torres Machado, L. Toscano, D. Y. Tou, C. Trippl, G. Tuci, N. Tuning, L. H. Uecker, A. Ukleja, D. J. Unverzagt, E. Ursov, A. Usachov, A. Ustyuzhanin, U. Uwer, V. Vagnoni, V. Valcarce Cadenas, G. Valenti, N. Valls Canudas, H. Van Hecke, E. van Herwijnen, C. B. Van Hulse, R. Van Laak, M. van Veghel, G. Vasquez, R. Vazquez Gomez, P. Vazquez Regueiro, C. Vázquez Sierra, S. Vecchi, J. J. Velthuis, M. Veltri, A. Venkateswaran, M. Verdoglia, M. Vesterinen, D. Vico Benet, P. V. Vidrier Villalba, M. Vieites Diaz, X. Vilasis-Cardona, E. Vilella Figueras, A. Villa, P. Vincent, F. C. Volle, D. vom Bruch, N. Voropaev, K. Vos, G. Vouters, C. Vrahas, J. Wagner, J. Walsh, E. J. Walton, G. Wan, C. Wang, G. Wang, J. Wang, M. Wang, N. W. Wang, R. Wang, X. Wang, X. W. Wang, Y. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, J. Wendel, B. D. C. Westhenry, C. White, M. Whitehead, E. Whiter, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, Z. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, Z. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, K. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, Y Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, F. Zenesini, C. Zeng, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, S. Z. Zheng, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: Hadron-Hadron Scattering, Quarkonium, Spectroscopy, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract The decays of the χb1(1P), χb2(1P), χb1(2P) and χb2(2P) mesons into the Υ(1S)μ+μ − final state are observed with a high significance using proton-proton collision data collected with the LHCb detector and corresponding to an integrated luminosity of 9 fb −1. The newly observed decays together with the Υ(2S) → Υ(1S)π+π − and Υ(3S) → Υ(2S)π+π − decay modes are used for precision measurements of the mass and mass splittings for the hidden-beauty states.
Published: 2024
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16. Transverse polarization measurement of Λ hyperons in pNe collisions at s NN $$ \sqrt{{\textrm{s}}_{\textrm{NN}}} $$ = 68.4 GeV with the LHCb detector

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, R. Ataide Da Silva, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, H. Bao, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, M. Barnyakov, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, J. M. Basels, G. Bassi, B. Batsukh, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, S. Calderon Ramirez, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, P. Camargo Magalhaes, J. I. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. Carcedo Salgado, R. Cardinale, A. Cardini, P. Carniti, L. Carus, A. Casais Vidal, R. Caspary, G. Casse, J. Castro Godinez, M. Cattaneo, G. Cavallero, V. Cavallini, S. Celani, D. Cervenkov, S. Cesare, A. J. Chadwick, I. Chahrour, M. Charles, Ph. Charpentier, E. Chatzianagnostou, C. A. Chavez Barajas, M. Chefdeville, C. Chen, S. Chen, Z. Chen, A. Chernov, S. Chernyshenko, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. Cifra, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Cocha Toapaxi, V. Coco, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, L. Congedo, A. Contu, N. Cooke, I. Corredoira, A. Correia, G. Corti, J. J. Cottee Meldrum, B. Couturier, D. C. Craik, M. Cruz Torres, E. Curras Rivera, R. Currie, C. L. Da Silva, S. Dadabaev, L. Dai, X. Dai, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, J. Daniel, A. Danilina, P. d’Argent, A. Davidson, J. E. Davies, A. Davis, O. De Aguiar Francisco, C. De Angelis, F. De Benedetti, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. Feng, M. Feo, M. Fernandez Gomez, A. D. Fernez, F. Ferrari, F. Ferreira Rodrigues, M. Ferrillo, M. Ferro-Luzzi, S. Filippov, R. A. Fini, M. Fiorini, K. M. Fischer, D. S. Fitzgerald, C. Fitzpatrick, F. Fleuret, M. Fontana, L. F. Foreman, R. Forty, D. Foulds-Holt, M. Franco Sevilla, M. Frank, E. Franzoso, G. Frau, C. Frei, D. A. Friday, J. Fu, Q. Fuehring, Y. Fujii, T. Fulghesu, E. Gabriel, G. Galati, M. D. Galati, A. Gallas Torreira, D. Galli, S. Gambetta, M. Gandelman, P. Gandini, B. Ganie, H. Gao, R. Gao, Y. Gao, M. Garau, L. M. Garcia Martin, P. Garcia Moreno, J. García Pardiñas, K. G. Garg, L. Garrido, C. Gaspar, R. E. Geertsema, L. L. Gerken, E. Gersabeck, M. Gersabeck, T. Gershon, Z. Ghorbanimoghaddam, L. Giambastiani, F. I. Giasemis, V. Gibson, H. K. Giemza, A. L. Gilman, M. Giovannetti, A. Gioventù, P. Gironella Gironell, C. Giugliano, M. A. Giza, E. L. Gkougkousis, F. C. Glaser, V. V. Gligorov, C. Göbel, E. Golobardes, D. Golubkov, A. Golutvin, A. Gomes, S. Gomez Fernandez, F. Goncalves Abrantes, M. Goncerz, G. Gong, J. A. Gooding, I. V. Gorelov, C. Gotti, J. P. Grabowski, L. A. Granado Cardoso, E. Graugés, E. Graverini, L. Grazette, G. Graziani, A. T. Grecu, L. M. Greeven, N. A. Grieser, L. Grillo, S. Gromov, C. Gu, M. Guarise, M. Guittiere, V. Guliaeva, P. A. Günther, A.-K. Guseinov, E. Gushchin, Y. Guz, T. Gys, K. Habermann, T. Hadavizadeh, C. Hadjivasiliou, G. Haefeli, C. Haen, J. Haimberger, M. Hajheidari, M. M. Halvorsen, P. M. Hamilton, J. Hammerich, Q. Han, X. Han, S. Hansmann-Menzemer, L. Hao, N. Harnew, M. Hartmann, J. He, F. Hemmer, C. Henderson, R. D. L. Henderson, A. M. Hennequin, K. Hennessy, L. Henry, J. Herd, P. Herrero Gascon, J. Heuel, A. Hicheur, G. Hijano Mendizabal, D. Hill, S. E. Hollitt, J. Horswill, R. Hou, Y. Hou, N. Howarth, J. Hu, W. Hu, X. Hu, W. Huang, W. Hulsbergen, R. J. Hunter, M. Hushchyn, D. Hutchcroft, D. Ilin, P. Ilten, A. Inglessi, A. Iniukhin, A. Ishteev, K. Ivshin, R. Jacobsson, H. Jage, S. J. Jaimes Elles, S. Jakobsen, E. Jans, B. K. Jashal, A. Jawahery, V. Jevtic, E. Jiang, X. Jiang, Y. Jiang, Y. J. Jiang, M. John, D. Johnson, C. R. Jones, T. P. Jones, S. Joshi, B. Jost, N. Jurik, I. Juszczak, D. Kaminaris, S. Kandybei, Y. Kang, C. Kar, M. Karacson, D. Karpenkov, A. Kauniskangas, J. W. Kautz, F. Keizer, M. Kenzie, T. Ketel, B. Khanji, A. Kharisova, S. Kholodenko, G. Khreich, T. Kirn, V. S. Kirsebom, O. Kitouni, S. Klaver, N. Kleijne, K. Klimaszewski, M. R. Kmiec, S. Koliiev, L. Kolk, A. Konoplyannikov, P. Kopciewicz, P. Koppenburg, M. Korolev, I. Kostiuk, O. Kot, S. Kotriakhova, A. Kozachuk, P. Kravchenko, L. Kravchuk, M. Kreps, P. Krokovny, W. Krupa, W. Krzemien, O. K. Kshyvanskyi, J. Kubat, S. Kubis, M. Kucharczyk, V. Kudryavtsev, E. Kulikova, A. Kupsc, B. K. Kutsenko, D. Lacarrere, A. Lai, A. Lampis, D. Lancierini, C. Landesa Gomez, J. J. Lane, R. Lane, C. Langenbruch, J. Langer, O. Lantwin, T. Latham, F. Lazzari, C. Lazzeroni, R. Le Gac, R. Lefèvre, A. Leflat, S. Legotin, M. Lehuraux, E. Lemos Cid, O. Leroy, T. Lesiak, B. Leverington, A. Li, H. Li, K. Li, L. Li, P. Li, P.-R. Li, Q. Li, S. Li, T. Li, Y. Li, Z. Lian, X. Liang, S. Libralon, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, K. Liu, S. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, C. Lucarelli, D. Lucchesi, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. M. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. Massafferri, R. Matev, A. Mathad, V. Matiunin, C. Matteuzzi, K. R. Mattioli, A. Mauri, E. Maurice, J. Mauricio, P. Mayencourt, M. Mazurek, M. McCann, L. Mcconnell, T. H. McGrath, N. T. McHugh, A. McNab, R. McNulty, B. Meadows, G. Meier, D. Melnychuk, F. M. Meng, M. Merk, A. Merli, L. Meyer Garcia, D. Miao, H. Miao, M. Mikhasenko, D. A. Milanes, A. Minotti, E. Minucci, T. Miralles, B. Mitreska, D. S. Mitzel, A. Modak, A. Mödden, R. A. Mohammed, R. D. Moise, S. Mokhnenko, T. Mombächer, M. Monk, S. Monteil, A. Morcillo Gomez, G. Morello, M. J. Morello, M. P. Morgenthaler, A. B. Morris, A. G. Morris, R. Mountain, H. Mu, Z. M. Mu, E. Muhammad, F. Muheim, M. Mulder, K. Müller, F. Muñoz-Rojas, R. Murta, P. Naik, T. Nakada, R. Nandakumar, T. Nanut, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, P. Neustroev, J. Nicolini, D. Nicotra, E. M. Niel, N. Nikitin, P. Nogarolli, P. Nogga, N. S. Nolte, C. Normand, J. Novoa Fernandez, G. Nowak, C. Nunez, H. N. Nur, A. Oblakowska-Mucha, V. Obraztsov, T. Oeser, S. Okamura, A. Okhotnikov, O. Okhrimenko, R. Oldeman, F. Oliva, M. Olocco, C. J. G. Onderwater, R. H. O’Neil, J. M. Otalora Goicochea, P. Owen, A. Oyanguren, O. Ozcelik, K. O. Padeken, B. Pagare, P. R. Pais, T. Pajero, A. Palano, M. Palutan, G. Panshin, L. Paolucci, A. Papanestis, M. Pappagallo, L. L. Pappalardo, C. Pappenheimer, C. Parkes, B. Passalacqua, G. Passaleva, D. Passaro, A. Pastore, M. Patel, J. Patoc, C. Patrignani, A. Paul, C. J. Pawley, A. Pellegrino, J. Peng, M. Pepe Altarelli, S. Perazzini, D. Pereima, H. Pereira Da Costa, A. Pereiro Castro, P. Perret, A. Perro, K. Petridis, A. Petrolini, J. P. Pfaller, H. Pham, L. Pica, M. Piccini, B. Pietrzyk, G. Pietrzyk, D. Pinci, F. Pisani, M. Pizzichemi, V. Placinta, M. Plo Casasus, F. Polci, M. Poli Lener, A. Poluektov, N. Polukhina, I. Polyakov, E. Polycarpo, S. Ponce, D. Popov, S. Poslavskii, K. Prasanth, C. Prouve, V. Pugatch, G. Punzi, S. Qasim, Q. Q. Qian, W. Qian, N. Qin, S. Qu, R. Quagliani, R. I. Rabadan Trejo, J. H. Rademacker, M. Rama, M. Ramírez García, V. Ramos De Oliveira, M. Ramos Pernas, M. S. Rangel, F. Ratnikov, G. Raven, M. Rebollo De Miguel, F. Redi, J. Reich, F. Reiss, Z. Ren, P. K. Resmi, R. Ribatti, G. R. Ricart, D. Riccardi, S. Ricciardi, K. Richardson, M. Richardson-Slipper, K. Rinnert, P. Robbe, G. Robertson, E. Rodrigues, E. Rodriguez Fernandez, J. A. Rodriguez Lopez, E. Rodriguez Rodriguez, A. Rogovskiy, D. L. Rolf, P. Roloff, V. Romanovskiy, M. Romero Lamas, A. Romero Vidal, G. Romolini, F. Ronchetti, T. Rong, M. Rotondo, S. R. Roy, M. S. Rudolph, T. Ruf, M. Ruiz Diaz, R. A. Ruiz Fernandez, J. Ruiz Vidal, A. Ryzhikov, J. Ryzka, J. J. Saavedra-Arias, J. J. Saborido Silva, R. Sadek, N. Sagidova, D. Sahoo, N. Sahoo, B. Saitta, M. Salomoni, C. Sanchez Gras, I. Sanderswood, R. Santacesaria, C. Santamarina Rios, M. Santimaria, L. Santoro, E. Santovetti, A. Saputi, D. Saranin, A. S. Sarnatskiy, G. Sarpis, M. Sarpis, C. Satriano, A. Satta, M. Saur, D. Savrina, H. Sazak, L. G. Scantlebury Smead, A. Scarabotto, S. Schael, S. Scherl, M. Schiller, H. Schindler, M. Schmelling, B. Schmidt, S. Schmitt, H. Schmitz, O. Schneider, A. Schopper, N. Schulte, S. Schulte, M. H. Schune, R. Schwemmer, G. Schwering, B. Sciascia, A. Sciuccati, S. Sellam, A. Semennikov, T. Senger, M. Senghi Soares, A. Sergi, N. Serra, L. Sestini, A. Seuthe, Y. Shang, D. M. Shangase, M. Shapkin, R. S. Sharma, I. Shchemerov, L. Shchutska, T. Shears, L. Shekhtman, Z. Shen, S. Sheng, V. Shevchenko, B. Shi, Q. Shi, Y. Shimizu, E. Shmanin, R. Shorkin, J. D. Shupperd, R. Silva Coutinho, G. Simi, S. Simone, N. Skidmore, T. Skwarnicki, M. W. Slater, J. C. Smallwood, E. Smith, K. Smith, M. Smith, A. Snoch, L. Soares Lavra, M. D. Sokoloff, F. J. P. Soler, A. Solomin, A. Solovev, I. Solovyev, R. Song, Y. Song, Y. S. Song, F. L. Souza De Almeida, B. Souza De Paula, E. Spadaro Norella, E. Spedicato, J. G. Speer, E. Spiridenkov, P. Spradlin, V. Sriskaran, F. Stagni, M. Stahl, S. Stahl, S. Stanislaus, E. N. Stein, O. Steinkamp, O. Stenyakin, H. Stevens, D. Strekalina, Y. Su, F. Suljik, J. Sun, L. Sun, Y. Sun, D. S. Sundfeld Lima, W. Sutcliffe, P. N. Swallow, F. Swystun, A. Szabelski, T. Szumlak, Y. Tan, M. D. Tat, A. Terentev, F. Terzuoli, F. Teubert, E. Thomas, D. J. D. Thompson, H. Tilquin, V. Tisserand, S. T’Jampens, M. Tobin, L. Tomassetti, G. Tonani, X. Tong, D. Torres Machado, L. Toscano, D. Y. Tou, C. Trippl, G. Tuci, N. Tuning, L. H. Uecker, A. Ukleja, D. J. Unverzagt, E. Ursov, A. Usachov, A. Ustyuzhanin, U. Uwer, V. Vagnoni, G. Valenti, N. Valls Canudas, H. Van Hecke, E. van Herwijnen, C. B. Van Hulse, R. Van Laak, M. van Veghel, G. Vasquez, R. Vazquez Gomez, P. Vazquez Regueiro, C. Vázquez Sierra, S. Vecchi, J. J. Velthuis, M. Veltri, A. Venkateswaran, M. Vesterinen, M. Vieites Diaz, X. Vilasis-Cardona, E. Vilella Figueras, A. Villa, P. Vincent, F. C. Volle, D. vom Bruch, N. Voropaev, K. Vos, G. Vouters, C. Vrahas, J. Wagner, J. Walsh, E. J. Walton, G. Wan, C. Wang, G. Wang, J. Wang, M. Wang, N. W. Wang, R. Wang, X. Wang, X. W. Wang, Y. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, J. Wendel, B. D. C. Westhenry, D. J. White, M. Whitehead, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, K. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, C. Zeng, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, S. Z. Zheng, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: Fixed Target Experiments, Polarization, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract A measurement of the transverse polarization of the Λ and Λ ¯ $$ \overline{\varLambda} $$ hyperons in pNe fixed-target collisions at s NN $$ \sqrt{{\textrm{s}}_{\textrm{NN}}} $$ = 68.4 GeV is presented using data collected by the LHCb detector. The polarization is studied using the decay Λ → pπ − together with its charge conjugated process, the integrated values measured are P Λ = 0.029 ± 0.019 stat ± 0.012 syst , P Λ ¯ = 0.003 ± 0.023 stat ± 0.014 syst . $$ {\displaystyle \begin{array}{c}{P}_{\varLambda }=0.029\pm 0.019\left(\textrm{stat}\right)\pm 0.012\left(\textrm{syst}\right),\\ {}{P}_{\overline{\varLambda}}=0.003\pm 0.023\left(\textrm{stat}\right)\pm 0.014\left(\textrm{syst}\right).\end{array}} $$ Furthermore, the results are shown as a function of the Feynman x variable, transverse momentum, pseudorapidity and rapidity of the hyperons, and are compared with previous measurements.
Published: 2024
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17. Comprehensive analysis of local and nonlocal amplitudes in the B 0 → K *0 μ + μ − decay

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, R. Ataide Da Silva, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, H. Bao, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, M. Barnyakov, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, J. M. Basels, G. Bassi, B. Batsukh, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, S. Calderon Ramirez, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, P. Camargo Magalhaes, J. I. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. Carcedo Salgado, R. Cardinale, A. Cardini, P. Carniti, L. Carus, A. Casais Vidal, R. Caspary, G. Casse, J. Castro Godinez, M. Cattaneo, G. Cavallero, V. Cavallini, S. Celani, D. Cervenkov, S. Cesare, A. J. Chadwick, I. Chahrour, M. Charles, Ph. Charpentier, E. Chatzianagnostou, C. A. Chavez Barajas, M. Chefdeville, C. Chen, S. Chen, Z. Chen, A. Chernov, S. Chernyshenko, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. Cifra, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Cocha Toapaxi, V. Coco, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, L. Congedo, A. Contu, N. Cooke, I. Corredoira, A. Correia, G. Corti, J. J. Cottee Meldrum, B. Couturier, D. C. Craik, M. Cruz Torres, E. Curras Rivera, R. Currie, C. L. Da Silva, S. Dadabaev, L. Dai, X. Dai, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, J. Daniel, A. Danilina, P. d’Argent, A. Davidson, J. E. Davies, A. Davis, O. De Aguiar Francisco, C. De Angelis, F. De Benedetti, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. Feng, M. Feo, M. Fernandez Gomez, A. D. Fernez, F. Ferrari, F. Ferreira Rodrigues, M. Ferrillo, M. Ferro-Luzzi, S. Filippov, R. A. Fini, M. Fiorini, K. M. Fischer, D. S. Fitzgerald, C. Fitzpatrick, F. Fleuret, M. Fontana, L. F. Foreman, R. Forty, D. Foulds-Holt, M. Franco Sevilla, M. Frank, E. Franzoso, G. Frau, C. Frei, D. A. Friday, J. Fu, Q. Fuehring, Y. Fujii, T. Fulghesu, E. Gabriel, G. Galati, M. D. Galati, A. Gallas Torreira, D. Galli, S. Gambetta, M. Gandelman, P. Gandini, B. Ganie, H. Gao, R. Gao, Y. Gao, M. Garau, L. M. Garcia Martin, P. Garcia Moreno, J. García Pardiñas, K. G. Garg, L. Garrido, C. Gaspar, R. E. Geertsema, L. L. Gerken, E. Gersabeck, M. Gersabeck, T. Gershon, Z. Ghorbanimoghaddam, L. Giambastiani, F. I. Giasemis, V. Gibson, H. K. Giemza, A. L. Gilman, M. Giovannetti, A. Gioventù, P. Gironella Gironell, C. Giugliano, M. A. Giza, E. L. Gkougkousis, F. C. Glaser, V. V. Gligorov, C. Göbel, E. Golobardes, D. Golubkov, A. Golutvin, A. Gomes, S. Gomez Fernandez, F. Goncalves Abrantes, M. Goncerz, G. Gong, J. A. Gooding, I. V. Gorelov, C. Gotti, J. P. Grabowski, L. A. Granado Cardoso, E. Graugés, E. Graverini, L. Grazette, G. Graziani, A. T. Grecu, L. M. Greeven, N. A. Grieser, L. Grillo, S. Gromov, C. Gu, M. Guarise, M. Guittiere, V. Guliaeva, P. A. Günther, A.-K. Guseinov, E. Gushchin, Y. Guz, T. Gys, K. Habermann, T. Hadavizadeh, C. Hadjivasiliou, G. Haefeli, C. Haen, J. Haimberger, M. Hajheidari, M. M. Halvorsen, P. M. Hamilton, J. Hammerich, Q. Han, X. Han, S. Hansmann-Menzemer, L. Hao, N. Harnew, M. Hartmann, J. He, M. Hecker, F. Hemmer, C. Henderson, R. D. L. Henderson, A. M. Hennequin, K. Hennessy, L. Henry, J. Herd, P. Herrero Gascon, J. Heuel, A. Hicheur, G. Hijano Mendizabal, D. Hill, S. E. Hollitt, J. Horswill, R. Hou, Y. Hou, N. Howarth, J. Hu, W. Hu, X. Hu, W. Huang, W. Hulsbergen, R. J. Hunter, M. Hushchyn, D. Hutchcroft, D. Ilin, P. Ilten, A. Inglessi, A. Iniukhin, A. Ishteev, K. Ivshin, R. Jacobsson, H. Jage, S. J. Jaimes Elles, S. Jakobsen, E. Jans, B. K. Jashal, A. Jawahery, V. Jevtic, E. Jiang, X. Jiang, Y. Jiang, Y. J. Jiang, M. John, D. Johnson, C. R. Jones, T. P. Jones, S. Joshi, B. Jost, N. Jurik, I. Juszczak, D. Kaminaris, S. Kandybei, M. Kane, Y. Kang, C. Kar, M. Karacson, D. Karpenkov, A. Kauniskangas, J. W. Kautz, F. Keizer, M. Kenzie, T. Ketel, B. Khanji, A. Kharisova, S. Kholodenko, G. Khreich, T. Kirn, V. S. Kirsebom, O. Kitouni, S. Klaver, N. Kleijne, K. Klimaszewski, M. R. Kmiec, S. Koliiev, L. Kolk, A. Konoplyannikov, P. Kopciewicz, P. Koppenburg, M. Korolev, I. Kostiuk, O. Kot, S. Kotriakhova, A. Kozachuk, P. Kravchenko, L. Kravchuk, M. Kreps, P. Krokovny, W. Krupa, W. Krzemien, O. K. Kshyvanskyi, J. Kubat, S. Kubis, M. Kucharczyk, V. Kudryavtsev, E. Kulikova, A. Kupsc, B. K. Kutsenko, D. Lacarrere, A. Lai, A. Lampis, D. Lancierini, C. Landesa Gomez, J. J. Lane, R. Lane, C. Langenbruch, J. Langer, O. Lantwin, T. Latham, F. Lazzari, C. Lazzeroni, R. Le Gac, R. Lefèvre, A. Leflat, S. Legotin, M. Lehuraux, E. Lemos Cid, O. Leroy, T. Lesiak, B. Leverington, A. Li, H. Li, K. Li, L. Li, P. Li, P.-R. Li, Q. Li, S. Li, T. Li, Y. Li, Z. Lian, X. Liang, S. Libralon, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, K. Liu, S. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, C. Lucarelli, D. Lucchesi, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. J. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. Massafferri, R. Matev, A. Mathad, V. Matiunin, C. Matteuzzi, K. R. Mattioli, A. Mauri, E. Maurice, J. Mauricio, P. Mayencourt, M. Mazurek, M. McCann, L. Mcconnell, T. H. McGrath, N. T. McHugh, A. McNab, R. McNulty, B. Meadows, G. Meier, D. Melnychuk, F. M. Meng, M. Merk, A. Merli, L. Meyer Garcia, D. Miao, H. Miao, M. Mikhasenko, D. A. Milanes, A. Minotti, E. Minucci, T. Miralles, B. Mitreska, D. S. Mitzel, A. Modak, A. Mödden, R. A. Mohammed, R. D. Moise, S. Mokhnenko, T. Mombächer, M. Monk, S. Monteil, A. Morcillo Gomez, G. Morello, M. J. Morello, M. P. Morgenthaler, A. B. Morris, A. G. Morris, R. Mountain, H. Mu, Z. M. Mu, E. Muhammad, F. Muheim, M. Mulder, K. Müller, F. Muñoz-Rojas, R. Murta, P. Naik, T. Nakada, R. Nandakumar, T. Nanut, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, P. Neustroev, J. Nicolini, D. Nicotra, E. M. Niel, N. Nikitin, P. Nogarolli, P. Nogga, N. S. Nolte, C. Normand, J. Novoa Fernandez, G. Nowak, C. Nunez, H. N. Nur, A. Oblakowska-Mucha, V. Obraztsov, T. Oeser, S. Okamura, A. Okhotnikov, O. Okhrimenko, R. Oldeman, F. Oliva, M. Olocco, C. J. G. Onderwater, R. H. O’Neil, J. M. Otalora Goicochea, P. Owen, A. Oyanguren, O. Ozcelik, A. Padee, K. O. Padeken, B. Pagare, P. R. Pais, T. Pajero, A. Palano, M. Palutan, G. Panshin, L. Paolucci, A. Papanestis, M. Pappagallo, L. L. Pappalardo, C. Pappenheimer, C. Parkes, B. Passalacqua, G. Passaleva, D. Passaro, A. Pastore, M. Patel, J. Patoc, C. Patrignani, A. Paul, C. J. Pawley, A. Pellegrino, J. Peng, M. Pepe Altarelli, S. Perazzini, D. Pereima, H. Pereira Da Costa, A. Pereiro Castro, P. Perret, A. Perro, K. Petridis, A. Petrolini, J. P. Pfaller, H. Pham, L. Pica, M. Piccini, B. Pietrzyk, G. Pietrzyk, D. Pinci, F. Pisani, M. Pizzichemi, V. Placinta, M. Plo Casasus, F. Polci, M. Poli Lener, A. Poluektov, N. Polukhina, I. Polyakov, E. Polycarpo, G. J. Pomery, S. Ponce, D. Popov, S. Poslavskii, K. Prasanth, C. Prouve, V. Pugatch, G. Punzi, S. Qasim, Q. Q. Qian, W. Qian, N. Qin, S. Qu, R. Quagliani, R. I. Rabadan Trejo, J. H. Rademacker, M. Rama, M. Ramírez García, V. Ramos De Oliveira, M. Ramos Pernas, M. S. Rangel, F. Ratnikov, G. Raven, M. Rebollo De Miguel, F. Redi, J. Reich, F. Reiss, Z. Ren, P. K. Resmi, R. Ribatti, G. R. Ricart, D. Riccardi, S. Ricciardi, K. Richardson, M. Richardson-Slipper, K. Rinnert, P. Robbe, G. Robertson, E. Rodrigues, E. Rodriguez Fernandez, J. A. Rodriguez Lopez, E. Rodriguez Rodriguez, A. Rogovskiy, D. L. Rolf, P. Roloff, V. Romanovskiy, M. Romero Lamas, A. Romero Vidal, G. Romolini, F. Ronchetti, T. Rong, M. Rotondo, S. R. Roy, M. S. Rudolph, T. Ruf, M. Ruiz Diaz, R. A. Ruiz Fernandez, J. Ruiz Vidal, A. Ryzhikov, J. Ryzka, J. J. Saavedra-Arias, J. J. Saborido Silva, R. Sadek, N. Sagidova, D. Sahoo, N. Sahoo, B. Saitta, M. Salomoni, C. Sanchez Gras, I. Sanderswood, R. Santacesaria, C. Santamarina Rios, M. Santimaria, L. Santoro, E. Santovetti, A. Saputi, D. Saranin, A. S. Sarnatskiy, G. Sarpis, M. Sarpis, C. Satriano, A. Satta, M. Saur, D. Savrina, H. Sazak, L. G. Scantlebury Smead, A. Scarabotto, S. Schael, S. Scherl, M. Schiller, H. Schindler, M. Schmelling, B. Schmidt, S. Schmitt, H. Schmitz, O. Schneider, A. Schopper, N. Schulte, S. Schulte, M. H. Schune, R. Schwemmer, G. Schwering, B. Sciascia, A. Sciuccati, S. Sellam, A. Semennikov, T. Senger, M. Senghi Soares, A. Sergi, N. Serra, L. Sestini, A. Seuthe, Y. Shang, D. M. Shangase, M. Shapkin, R. S. Sharma, I. Shchemerov, L. Shchutska, T. Shears, L. Shekhtman, Z. Shen, S. Sheng, V. Shevchenko, B. Shi, Q. Shi, Y. Shimizu, E. Shmanin, R. Shorkin, J. D. Shupperd, R. Silva Coutinho, G. Simi, S. Simone, N. Skidmore, T. Skwarnicki, M. W. Slater, J. C. Smallwood, E. Smith, K. Smith, M. Smith, A. Snoch, L. Soares Lavra, M. D. Sokoloff, F. J. P. Soler, A. Solomin, A. Solovev, I. Solovyev, R. Song, Y. Song, Y. S. Song, F. L. Souza De Almeida, B. Souza De Paula, E. Spadaro Norella, E. Spedicato, J. G. Speer, E. Spiridenkov, P. Spradlin, V. Sriskaran, F. Stagni, M. Stahl, S. Stahl, S. Stanislaus, E. N. Stein, O. Steinkamp, O. Stenyakin, H. Stevens, D. Strekalina, Y. Su, F. Suljik, J. Sun, L. Sun, Y. Sun, D. S. Sundfeld Lima, W. Sutcliffe, P. N. Swallow, F. Swystun, A. Szabelski, T. Szumlak, Y. Tan, M. D. Tat, A. Terentev, F. Terzuoli, F. Teubert, E. Thomas, D. J. D. Thompson, H. Tilquin, V. Tisserand, S. T’Jampens, M. Tobin, L. Tomassetti, G. Tonani, X. Tong, D. Torres Machado, L. Toscano, D. Y. Tou, C. Trippl, G. Tuci, N. Tuning, L. H. Uecker, A. Ukleja, D. J. Unverzagt, E. Ursov, A. Usachov, A. Ustyuzhanin, U. Uwer, V. Vagnoni, G. Valenti, N. Valls Canudas, H. Van Hecke, E. van Herwijnen, C. B. Van Hulse, R. Van Laak, M. van Veghel, G. Vasquez, R. Vazquez Gomez, P. Vazquez Regueiro, C. Vázquez Sierra, S. Vecchi, J. J. Velthuis, M. Veltri, A. Venkateswaran, M. Vesterinen, M. Vieites Diaz, X. Vilasis-Cardona, E. Vilella Figueras, A. Villa, P. Vincent, F. C. Volle, D. vom Bruch, N. Voropaev, K. Vos, G. Vouters, C. Vrahas, J. Wagner, J. Walsh, E. J. Walton, G. Wan, C. Wang, G. Wang, J. Wang, M. Wang, N. W. Wang, R. Wang, X. Wang, X. W. Wang, Y. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, J. Wendel, B. D. C. Westhenry, D. J. White, M. Whitehead, E. Whiter, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, K. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, C. Zeng, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, S. Z. Zheng, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: B Physics, Flavour Changing Neutral Currents, Flavour Physics, Hadron-Hadron Scattering, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract A comprehensive study of the local and nonlocal amplitudes contributing to the decay B 0 → K *0(→ K + π − )μ + μ − is performed by analysing the phase-space distribution of the decay products. The analysis is based on pp collision data corresponding to an integrated luminosity of 8.4 fb −1 collected by the LHCb experiment. This measurement employs for the first time a model of both one-particle and two-particle nonlocal amplitudes, and utilises the complete dimuon mass spectrum without any veto regions around the narrow charmonium resonances. In this way it is possible to explicitly isolate the local and nonlocal contributions and capture the interference between them. The results show that interference with nonlocal contributions, although larger than predicted, only has a minor impact on the Wilson Coefficients determined from the fit to the data. For the local contributions, the Wilson Coefficient C 9 $$ {\mathcal{C}}_9 $$ , responsible for vector dimuon currents, exhibits a 2.1σ deviation from the Standard Model expectation. The Wilson Coefficients C 10 $$ {\mathcal{C}}_{10} $$ , C 9 ′ $$ {\mathcal{C}}_9^{\prime } $$ and C 10 ′ $$ {\mathcal{C}}_{10}^{\prime } $$ are all in better agreement than C 9 $$ {\mathcal{C}}_9 $$ with the Standard Model and the global significance is at the level of 1.5σ. The model used also accounts for nonlocal contributions from B 0 → K *0[τ + τ − → μ + μ − ] rescattering, resulting in the first direct measurement of the bsττ vector effective-coupling C 9 τ $$ {\mathcal{C}}_{9\tau } $$ .
Published: 2024
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18. Heterotrophic and Photoautotrophic Media Optimization Using Response Surface Methodology for the Novel Microalga Chlorococcum amblystomatis

Author: Nádia Correia, Hugo Pereira, Peter S. C. Schulze, Monya M. Costa, Gonçalo E. Santo, Inês Guerra, Mafalda Trovão, Ana Barros, Helena Cardoso, Joana L. Silva, Luísa Gouveia, and João Varela
Subjects: Fluid Flow and Transfer Processes, Process Chemistry and Technology, Photoautotrophic production, General Engineering, Extraction, Hetero- and photoautotrophic cultivation, Computer Science Applications, Growth optimization, microalgae, Chlorococcum amblystomatis, growth optimization, response surface methodology, hetero- and photoautotrophic cultivation, Response surface methodology, Microalgae, General Materials Science, Fatty acids, Instrumentation
Abstract: The nutritional requirements of novel microalgal strains are key for their effective cultivation and metabolite content. Therefore, the optimization of heterotrophic and photoautotrophic culture media is crucial for novel Chlorococcum amblystomatis growth. Heterotrophic and photoautotrophic biomass samples were characterized to identify the differences between their heterotrophic and photoautotrophic biomass composition and their biotechnological potential. Media optimization through surface response methodology led to 44.9 and 51.2% increments in C. amblystomatis-specific growth rates under heterotrophic and photoautotrophic growth, respectively. This microalga registered high protein content (61.49–73.45% dry weight), with the highest value being observed in the optimized photoautotrophic growth medium. The lipid fraction mainly constituted polyunsaturated fatty acids, ranging from 44.47 to 51.41% for total fatty acids (TFA) in cells under heterotrophy. However, these contents became significantly higher (70.46–72.82% TFA) in cultures cultivated under photoautotrophy. An interesting carotenoids content was achieved in the cultures grown in optimized photoautotrophic medium: 5.84 mg·g−1 β-carotene, 5.27 mg·g−1 lutein, 3.66 mg·g−1 neoxanthin, and 0.75 mg·g−1 violaxanthin. Therefore, C. amblystomatis demonstrated an interesting growth performance and nutritional profile for food supplements and feed products that might contribute to meeting the world’s nutritional demand. LISBOA-01-0247-FEDER-035234 LA/P/0101/2020 POCI-01-0247-FEDER-035234 023310–ALGACO2 ALG-01-0247-FEDER-035234 ALG-01-0247-FEDER-069961 info:eu-repo/semantics/publishedVersion
Published: 2023

19. FOXO3A-short is a novel regulator of non-oxidative glucose metabolism associated with human longevity

Author: Rogier Versteeg, Jihye Paik, Evan E. Santo, Ninna S. Hansen, Peter Stroeken, Vincent C.J. de Boer, Ellen M. Westerhout, Rasmus Ribel-Madsen, Allan Vaag, and Maaike Commandeur
Subjects: Untranslated region, Aging, Gene knockdown, Myogenesis, Insulin, medicine.medical_treatment, Skeletal muscle, Cell Biology, Biology, Carbohydrate metabolism, Cell biology, medicine.anatomical_structure, Human and Animal Physiology, medicine, WIAS, Fysiologie van Mens en Dier, Life Science, Glycolysis, Nuclear protein
Abstract: In humans, intronic polymorphisms in FOXO3A are associated with extreme longevity. Despite many studies reporting this association it is unclear how these polymorphisms alter FOXO3A functionality and human physiology thereby influencing human lifespan. Here, we identify a novel minimally conserved FOXO3A transcriptional isoform, FOXO3A-Short (FOXO3A-S), encoding a major longevity-associated single-nucleotide polymorphism, rs9400239 (C or T), within its 5’ untranslated region. Strikingly, the FOXO3A-S mRNA is highly expressed in skeletal muscle and has very limited expression in other tissues. We find that the rs9400239 variant influences the stability and functionality of the primarily nuclear protein(s) encoded by the FOXO3A-S mRNA. Assessment of the relationship between the FOXO3A-S polymorphism and peripheral glucose clearance during insulin infusion (Rd clamp) in a cohort of Danish twins revealed that longevity T-allele carriers have markedly faster peripheral glucose clearance rates than normal lifespan C-allele carriers. In vitro experiments in human myotube cultures utilizing overexpression of each allele showed that the C-allele repressed glycolysis independently of PI3K signaling while overexpression of the T-allele repressed glycolysis only in a PI3K-inactive background. Supporting this finding inducible knockdown of the FOXO3A-S C-allele in cultured myotubes increased the glycolytic rate. We conclude that the rs9400239 polymorphism acts as a molecular switch which changes the identity of the FOXO3A-S-derived protein(s) which in turn alters the relationship between FOXO3A-S and insulin/PI3K signaling and glycolytic flux in skeletal muscle. This critical difference endows carriers of the FOXO3A-S T-allele with consistently higher insulin-stimulated peripheral glucose clearance rates which may contribute to their longer and healthier lifespans.
Published: 2023

20. Female nurses have a higher prevalence of urinary tract symptoms and infection than other occupations in dialysis units

Author: Fabiana B Nerbass, Cintia E Santo, Edilaine V Fialek, Viviane Calice-Silva, and Marcos A Vieira
Subjects: Adult, Nephrology, medicine.medical_specialty, Urinary urgency, medicine.medical_treatment, Urinary system, Population, 030232 urology & nephrology, Psychological intervention, Nurses, Hydration, Urine, Occupational safety and health, 03 medical and health sciences, 0302 clinical medicine, Lower Urinary Tract Symptoms, Renal Dialysis, Internal medicine, Prevalence, medicine, Humans, 030212 general & internal medicine, Occupations, Urinary Tract, education, Toilet Behavior, Occupational Health, Dialysis, education.field_of_study, business.industry, General Medicine, Middle Aged, Urinary Tract Symptom, Diseases of the genitourinary system. Urology, Urinary Tract Infection, Cross-Sectional Studies, Female, RC870-923, medicine.symptom, business
Abstract: Introduction: Urinary tract symptoms and infection have been associated with occupational factors that impact hydration habits particularly in women. We compared self-reported urinary symptoms and infection and hydration habits between nurses and other occupations in dialysis units. Methods: Cross-sectional study. Participants worked in five nephrology centers in Brazil and answered an online questionnaire comprising questions regarding urinary tract symptoms and infection episodes in the preceding year; data on usual daily beverage intake, urine frequency, and urine color according to a urine color chart were also collected, as well as perceptions of water access and toilet adequacy at work. Results: We included 133 women (age=36.9±9.5 years). The self-reported usual daily beverage intake was 6.6±2.9 cups/day (~1320 mL), daily urine frequency was 5.4±2.1, and urine color chart score: 3.0±1.2. Nurses (N=66/49.6%) reported higher prevalence of burning sensation (50 versus 27%; P
Published: 2021

21. Use of electrolytic processes applied as an alternative treatment to chlorine in water pretreatment in reverse osmosis system

Author: Yara B. R. E. Santo, Thamires M. Cruz, Rocio P. B. Hernandez, and Éder B. Silveira
Abstract: Reverse osmosis filtration is one of the water treatments used by industry because it is very effective in removing dissolved salts from water since it uses a specific type of thin, semi permeable membrane. These membranes have characteristically small pores to allow the passage of pure water and reject larger molecules, such as ions and other tiny impurities like bacteria and viruses. Several precautions need to be considered in water treatment before starting the filtration process in the equipment. These precautions are necessary to avoid premature loss of the membranes in the reverse osmosis system equipment. One of the most common problems that cause this damage is the oxidation reaction of the polyamide layer by the chlorine-based disinfectant, which corrodes this layer, substantially decreasing its filtration properties. The objective of this study, therefore, was to verify the possibility of substituting the use of chlorine in water treatment, for the removal of microorganisms, by the passage of an electric current, reducing the probability of biofilm formation and membrane perforation. The methodology consisted of experimental research, to verify the efficiency of the electric current as a biocide in a sample of raw water with cultivated microorganisms. An electrical load of 24 volts was applied, varying the exposure time, using Copper and Stainless Steel 304 as electrodes. The final results showed that in the treatment with the copper electrode and 30-minute retention of the water the results were satisfactory, and the treatment, therefore, could be used in conjunction with other biocides or in isolation reaching up to 103 CFU/ml of Aerobic Bacteria in the feed water.
Published: 2021

22. Learning context to adapt business processes.

Author: Juliana do E. Santo Carvalho, Flávia Maria Santoro, Kate Revoredo, and Vanessa Tavares Nunes
Published: 2013
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23. An Exploratory Study on Collaboratively Conceptualizing Knowledge Intensive Processes.

Author: Juliana Baptista dos Santos França, Joanne Manhães Netto, Juliana do E. Santo Carvalho, Flávia Maria Santoro, Fernanda Araújo Baião, and Mariano Gomes Pimentel
Published: 2012
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24. Three-dimensional catalysis and the efficient bioelectrocatalysis beyond surface chemistry

Author: Frank N. Crespilho, Graziela C. Sedenho, Lucyano J. A. Macedo, Gustavo Troiano Feliciano, Rodrigo M. Iost, Anderson A. E. Santo, Ayaz Hassan, Universidade de São Paulo (USP), and Universidade Estadual Paulista (UNESP)
Subjects: X-ray absorption spectroscopy, Chemistry, Electronic structure, CATÁLISE, Heterogeneous catalysis, Redox, Catalysis, Transition state, Multi-copper oxidases, Oxygen reduction reaction, Electron transfer, Chemical physics, Biocatalysis, 3D-catalysis, Physical and Theoretical Chemistry, Spectroelectrochemistry, Bilirubin oxidase
Abstract: Made available in DSpace on 2022-04-28T19:42:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-01 The exceptional catalysis for the oxygen reduction reaction (ORR) of bilirubin oxidase (BOD) encouraged us to reevaluate the existing catalytic models. Experimental evidence of the electron-transfer reaction's dependence on the three-dimensional structure of BOD is demonstrated by operando X-ray absorption spectroscopy (XAS) combined with Quantum Mechanics/Molecular Mechanics (QM/MM). We suggest that if a catalytic reaction occurs in a three-dimensional environment (3D-catalysis), the energies involved in the transition states during the electron transfer cannot be explained by adsorption kinetics. In contrast, there is the formation of a three-dimensional complex (TDC). Our data suggest influence of the metallic cofactor electronic structure as well as the spatial disposition of its surrounding ligands on the electron transfer that promotes the biocatalysis. We propose that investigating enzymatic redox processes involving a dynamic three-dimensional enzymatic structure can provide further insights as how heterogeneous catalysis can work beyond single atoms and surface chemistry. São Carlos Institute of Chemistry University of São Paulo Institute of Chemistry São Paulo State University Institute of Chemistry São Paulo State University
Published: 2021

25. Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases

Author: Raphael Dos Santos Morais, Paulo E. Santo, Marie Ley, Cédric Schelcher, Yoann Abel, Laura Plassart, Evolène Deslignière, Marie-Eve Chagot, Marc Quinternet, Ana C.F. Paiva, Steve Hessmann, Nelly Morellet, Pedro M. F. Sousa, Franck Vandermoere, Edouard Bertrand, Bruno Charpentier, Tiago M. Bandeiras, Célia Plisson-Chastang, Céline Verheggen, Sarah Cianférani, Xavier Manival, Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Instituto de Biologia Experimental e Tecnológica (IBET), Instituto de Tecnologia Química e Biológica António Xavier (ITQB), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), Laboratoire de Spectrométrie de Masse BioOrganique [Strasbourg] (LSMBO), Département Sciences Analytiques et Interactions Ioniques et Biomoléculaires (DSA-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Infrastructure Nationale de Protéomique, FR2048 ProFI, Institut de génétique humaine (IGH), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Unité de biologie moléculaire, cellulaire et du développement (MCD), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Ingénierie, Biologie et Santé en Lorraine (IBSLor), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie des Substances Naturelles (ICSN), Institut de Chimie du CNRS (INC)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), ANR-16-CE11-0032,snoRNPASSEMBLY,Comprendre l'assemblage des complexes macro-moléculaires en utilisant les snoRNP C/D comme modèle(2016), CIANFERANI, Sarah, and Comprendre l'assemblage des complexes macro-moléculaires en utilisant les snoRNP C/D comme modèle - - snoRNPASSEMBLY2016 - ANR-16-CE11-0032 - AAPG2016 - VALID
Subjects: [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Saxs, Structural Biology, Em, [CHIM] Chemical Sciences, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, Humans, [CHIM]Chemical Sciences, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Lumier-IP, Molecular Biology, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, XL-MS, Dpcd, DNA Helicases, Proteins, structural MS, Itc, Nmr, [SDV] Life Sciences [q-bio], Ruvbl1, Ruvbl2, Multiprotein Complexes, Silac-IP, ATPases Associated with Diverse Cellular Activities, Carrier Proteins
Abstract: International audience; DPCD is a protein that may play a role in cilia formation and whose absence leads to primary ciliary dyskinesia (PCD), a rare disease caused by impairment of ciliated cells. Except for high-throughput studies that identified DPCD as a possible RUVBL1 (R1) and RUVBL2 (R2) partner, no in-depth cellular, biochemical, and structural investigation involving DPCD have been reported so far. R1 and R2 proteins are ubiquitous highly conserved AAA + family ATPases that assemble and mature a plethora of macromolecular complexes and are pivotal in numerous cellular processes, especially by guaranteeing a co-chaperoning function within R2TP or R2TP-like machineries. In the present study, we identified DPCD as a new R1R2 partner in vivo. We show that DPCD interacts directly with R1 and R2 in vitro and in cells. We characterized the physico-chemical properties of DPCD in solution and built a 3D model of DPCD. In addition, we used a variety of orthogonal biophysical techniques including small-angle X-ray scattering, structural mass spectrometry and electron microscopy to assess the molecular determinants of DPCD interaction with R1R2. Interestingly, DPCD disrupts the dodecameric state of R1R2 complex upon binding and this interaction occurs mainly via the DII domains of R1R2.
Published: 2022

26. Contrast-induced nephropathy following PCI: can we calculate a safe contrast volume?

Author: H Costa, M Silva, M E Santo, T Mota, R Fernandes, H Palmeiro, S Marto, P Franco, D Carvalho, J Bispo, J Guedes, J Mimoso, A Marreiros, H Vinhas, and I Jesus
Subjects: Cardiology and Cardiovascular Medicine
Abstract: Introduction Acute kidney injury (AKI) due to contrast induced nephropathy (CIN) is a common complication after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS), and is associated with prolonged hospitalizations and elevated cardio and renovascular morbidity. Scientific evidence demonstrates that the mean volume of contrast (VolC) and ratio with creatinine clearance (CrCl) (VolC/CrCl) are independent predictors of CIN, but the accepted optimal value remains controversial. Objective Population characterization. To evaluate whether the calculation of VolC using the VolC/ClCr ratio Methods Retrospective study between 2017/2020, composed of n=378 patients who suffered ACS. Descriptve analysis was carried out regarding the demographic and clinical characteristics of the patients. Chi-Square test was used for categorical variables and the T-Student test for numerical variables, with a significance level of 95%. Results A total of 378 patients were identified, with a mean age of 64.5±11.2 years, 78.6% were male. 60.1% had hypertension, 48.4% dyslipidemia, 24.3% diabetes, 2.6% chronic renal failure (CRF) and 1.6% heart failure. Of these, 12.7% developed AKI ( Conclusion In patients submitted to ACS PCI, the development of AKI increases mortality, especial if AKI emerge after 24h. We report a more suitable ratio VolC/ClCr Funding Acknowledgement Type of funding sources: None.
Published: 2022

27. Os fatores determinantes e as complicações oriundas do crescimento fetal restrito

Author: Veiga, Tharín Marques, primary, Da Cruz, Taynara Rodrigues, additional, Simão, Roni, additional, Takatsu, Eduarda, additional, Almeida, Luis Henrique Fagundes, additional, Da Ponte, Isabella Maria Figueiredo Tuma, additional, Da Silva, Marlene Alencar, additional, de Carvalho, Catarinne Pacelli Benício, additional, Grings, Melina Stefania, additional, De Sousa, Geybssom Tarcio Evaristo, additional, Moreira e Santo, Bárbara Vitória Marinho, additional, Bastos, Eduardo Henrique Sarmento, additional, Machado, Bibiana Aparecida Pereira, additional, da Silva, Josielen Alexandria Serra, additional, Cunha, Marcos Antonio Pitaluga, additional, Cavalcante, Rafael Leituga de Carvalho, additional, Dos Santos, Dernevan Rodrigues, additional, Leite, Deivam São Leão, additional, Branco, Ketlen Michele Leite Rio, additional, Branco, Michele Leite Rio, additional, Costa, Ana Cláudia Rossi, additional, Segundo, Jorge da Silva, additional, Mai, Paulo Henrique, additional, Marques, Thiago Nominato, additional, Dourado, James Lucas Marques, additional, and Pereira, Jorge Eduardo Peixoto, additional
Published: 2022
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28. Dysfunctional Glymphatic System with Disrupted Aquaporin 4 Expression Pattern on Astrocytes Causes Bacterial Product Accumulation in the CSF during Pneumococcal Meningitis

Author: Jaqueline S, Generoso, Sigrun, Thorsdottir, Allan, Collodel, Diogo, Dominguini, Roberta R E, Santo, Fabricia, Petronilho, Tatiana, Barichello, and Federico, Iovino
Subjects: Aquaporin 4, Meningitis, Pneumococcal, Albumins, Astrocytes, Animals, Brain, Rats, Wistar, Glymphatic System, Rats
Abstract: Pneumococcal meningitis, inflammation of the meninges due to an infection of the Central Nervous System caused by Streptococcus pneumoniae (the pneumococcus), is the most common form of community-acquired bacterial meningitis globally. Aquaporin 4 (AQP4) water channels on astrocytic end feet regulate the solute transport of the glymphatic system, facilitating the exchange of compounds between the brain parenchyma and the cerebrospinal fluid (CSF), which is important for the clearance of waste away from the brain. Wistar rats, subjected to either pneumococcal meningitis or artificial CSF (sham control), received Evans blue-albumin (EBA) intracisternally. Overall, the meningitis group presented a significant impairment of the glymphatic system by retaining the EBA in the CSF compartments compared to the uninfected sham group. Our results clearly showed that during pneumococcal meningitis, the glymphatic system does not function because of a detachment of the astrocytic end feet from the blood-brain barrier (BBB) vascular endothelium, which leads to misplacement of AQP4 with the consequent loss of the AQP4 water channel's functionality.
Published: 2022

29. ParIS: a parameterizable interconnect switch for networks-on-chip.

Author: César Albenes Zeferino, Frederico G. M. E. Santo, and Altamiro Amadeu Susin
Published: 2004
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30. Amplitude analysis and branching fraction measurement of B + → D ∗ − D s + π + $$ {B}^{+}\to {D}^{\ast -}{D}_s^{+}{\pi}^{+} $$ decays

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, J. A. Adams, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, H. Bao, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, M. Barnyakov, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, F. Baryshnikov, J. M. Basels, G. Bassi, B. Batsukh, A. Battig, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, M. J. Bradley, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, S. Calderon Ramirez, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, J. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. Carcedo Salgado, R. Cardinale, A. Cardini, P. Carniti, L. Carus, A. Casais Vidal, R. Caspary, G. Casse, J. Castro Godinez, M. Cattaneo, G. Cavallero, V. Cavallini, S. Celani, D. Cervenkov, S. Cesare, A. J. Chadwick, I. Chahrour, M. Charles, Ph. Charpentier, C. A. Chavez Barajas, M. Chefdeville, C. Chen, S. Chen, Z. Chen, A. Chernov, S. Chernyshenko, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. Cifra, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Cocha Toapaxi, V. Coco, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, L. Congedo, A. Contu, N. Cooke, I. Corredoira, A. Correia, G. Corti, J. J. Cottee Meldrum, B. Couturier, D. C. Craik, M. Cruz Torres, E. Curras Rivera, R. Currie, C. L. Da Silva, S. Dadabaev, L. Dai, X. Dai, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, J. Daniel, A. Danilina, P. d’Argent, A. Davidson, J. E. Davies, A. Davis, O. De Aguiar Francisco, C. De Angelis, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, S. Ek-In, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. Feng, M. Feo, M. Fernandez Gomez, A. D. Fernez, F. Ferrari, F. Ferreira Rodrigues, S. Ferreres Sole, M. Ferrillo, M. Ferro-Luzzi, S. Filippov, R. A. Fini, M. Fiorini, K. M. Fischer, D. S. Fitzgerald, C. Fitzpatrick, F. Fleuret, M. Fontana, L. F. Foreman, R. Forty, D. Foulds-Holt, M. Franco Sevilla, M. Frank, E. Franzoso, G. Frau, C. Frei, D. A. Friday, J. Fu, Q. Fuehring, Y. Fujii, T. Fulghesu, E. Gabriel, G. Galati, M. D. Galati, A. Gallas Torreira, D. Galli, S. Gambetta, M. Gandelman, P. Gandini, B. Ganie, H. Gao, R. Gao, Y. Gao, M. Garau, L. M. Garcia Martin, P. Garcia Moreno, J. García Pardiñas, K. G. Garg, L. Garrido, C. Gaspar, R. E. Geertsema, L. L. Gerken, E. Gersabeck, M. Gersabeck, T. Gershon, Z. Ghorbanimoghaddam, L. Giambastiani, F. I. Giasemis, V. Gibson, H. K. Giemza, A. L. Gilman, M. Giovannetti, A. Gioventù, P. Gironella Gironell, C. Giugliano, M. A. Giza, E. L. Gkougkousis, F. C. Glaser, V. V. Gligorov, C. Göbel, E. Golobardes, D. Golubkov, A. Golutvin, A. Gomes, S. Gomez Fernandez, F. Goncalves Abrantes, M. Goncerz, G. Gong, J. A. Gooding, I. V. Gorelov, C. Gotti, J. P. Grabowski, L. A. Granado Cardoso, E. Graugés, E. Graverini, L. Grazette, G. Graziani, A. T. Grecu, L. M. Greeven, N. A. Grieser, L. Grillo, S. Gromov, C. Gu, M. Guarise, M. Guittiere, V. Guliaeva, P. A. Günther, A.-K. Guseinov, E. Gushchin, Y. Guz, T. Gys, K. Habermann, T. Hadavizadeh, C. Hadjivasiliou, G. Haefeli, C. Haen, J. Haimberger, M. Hajheidari, M. M. Halvorsen, P. M. Hamilton, J. Hammerich, Q. Han, X. Han, S. Hansmann-Menzemer, L. Hao, N. Harnew, M. Hartmann, J. He, F. Hemmer, C. Henderson, R. D. L. Henderson, A. M. Hennequin, K. Hennessy, L. Henry, J. Herd, J. Herdieckerhoff, P. Herrero Gascon, J. Heuel, A. Hicheur, G. Hijano Mendizabal, D. Hill, S. E. Hollitt, J. Horswill, R. Hou, Y. Hou, N. Howarth, J. Hu, W. Hu, X. Hu, W. Huang, W. Hulsbergen, R. J. Hunter, M. Hushchyn, D. Hutchcroft, D. Ilin, P. Ilten, A. Inglessi, A. Iniukhin, A. Ishteev, K. Ivshin, R. Jacobsson, H. Jage, S. J. Jaimes Elles, S. Jakobsen, E. Jans, B. K. Jashal, A. Jawahery, V. Jevtic, E. Jiang, X. Jiang, Y. Jiang, Y. J. Jiang, M. John, D. Johnson, C. R. Jones, T. P. Jones, S. Joshi, B. Jost, N. Jurik, I. Juszczak, D. Kaminaris, S. Kandybei, Y. Kang, C. Kar, M. Karacson, D. Karpenkov, A. M. Kauniskangas, J. W. Kautz, F. Keizer, M. Kenzie, T. Ketel, B. Khanji, A. Kharisova, S. Kholodenko, G. Khreich, T. Kirn, V. S. Kirsebom, O. Kitouni, S. Klaver, N. Kleijne, K. Klimaszewski, M. R. Kmiec, S. Koliiev, L. Kolk, A. Konoplyannikov, P. Kopciewicz, P. Koppenburg, M. Korolev, I. Kostiuk, O. Kot, S. Kotriakhova, A. Kozachuk, P. Kravchenko, L. Kravchuk, M. Kreps, P. Krokovny, W. Krupa, W. Krzemien, O. K. Kshyvanskyi, J. Kubat, S. Kubis, M. Kucharczyk, V. Kudryavtsev, E. Kulikova, A. Kupsc, B. K. Kutsenko, D. Lacarrere, A. Lai, A. Lampis, D. Lancierini, C. Landesa Gomez, J. J. Lane, R. Lane, C. Langenbruch, J. Langer, O. Lantwin, T. Latham, F. Lazzari, C. Lazzeroni, R. Le Gac, R. Lefèvre, A. Leflat, S. Legotin, M. Lehuraux, E. Lemos Cid, O. Leroy, T. Lesiak, B. Leverington, A. Li, H. Li, K. Li, L. Li, P. Li, P.-R. Li, Q. Li, S. Li, T. Li, Y. Li, Z. Lian, X. Liang, S. Libralon, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, K. Liu, S. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, C. Lucarelli, D. Lucchesi, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. M. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. J. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. Massafferri, R. Matev, A. Mathad, V. Matiunin, C. Matteuzzi, K. R. Mattioli, A. Mauri, E. Maurice, J. Mauricio, P. Mayencourt, M. Mazurek, M. McCann, L. Mcconnell, T. H. McGrath, N. T. McHugh, A. McNab, R. McNulty, B. Meadows, G. Meier, D. Melnychuk, F. M. Meng, M. Merk, A. Merli, L. Meyer Garcia, D. Miao, H. Miao, M. Mikhasenko, D. A. Milanes, A. Minotti, E. Minucci, T. Miralles, B. Mitreska, D. S. Mitzel, A. Modak, A. Mödden, R. A. Mohammed, R. D. Moise, S. Mokhnenko, T. Mombächer, M. Monk, S. Monteil, A. Morcillo Gomez, G. Morello, M. J. Morello, M. P. Morgenthaler, A. B. Morris, A. G. Morris, R. Mountain, H. Mu, Z. M. Mu, E. Muhammad, F. Muheim, M. Mulder, K. Müller, F. Muñoz-Rojas, R. Murta, P. Naik, T. Nakada, R. Nandakumar, T. Nanut, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, P. Neustroev, J. Nicolini, D. Nicotra, E. M. Niel, N. Nikitin, P. Nogga, N. S. Nolte, C. Normand, J. Novoa Fernandez, G. Nowak, C. Nunez, H. N. Nur, A. Oblakowska-Mucha, V. Obraztsov, T. Oeser, S. Okamura, R. Oldeman, F. Oliva, M. Olocco, C. J. G. Onderwater, R. H. O’Neil, J. M. Otalora Goicochea, P. Owen, A. Oyanguren, O. Ozcelik, K. O. Padeken, B. Pagare, P. R. Pais, T. Pajero, A. Palano, M. Palutan, G. Panshin, L. Paolucci, A. Papanestis, M. Pappagallo, L. L. Pappalardo, C. Pappenheimer, C. Parkes, B. Passalacqua, G. Passaleva, D. Passaro, A. Pastore, M. Patel, J. Patoc, C. Patrignani, C. J. Pawley, A. Pellegrino, J. Peng, M. Pepe Altarelli, S. Perazzini, D. Pereima, A. Pereiro Castro, P. Perret, A. Perro, K. Petridis, A. Petrolini, J. P. Pfaller, H. Pham, L. Pica, M. Piccini, B. Pietrzyk, G. Pietrzyk, D. Pinci, F. Pisani, M. Pizzichemi, V. Placinta, M. Plo Casasus, F. Polci, M. Poli Lener, A. Poluektov, N. Polukhina, I. Polyakov, E. Polycarpo, S. Ponce, D. Popov, S. Poslavskii, K. Prasanth, C. Prouve, V. Pugatch, G. Punzi, W. Qian, N. Qin, S. Qu, R. Quagliani, R. I. Rabadan Trejo, J. H. Rademacker, M. Rama, M. Ramírez García, M. Ramos Pernas, M. S. Rangel, F. Ratnikov, G. Raven, M. Rebollo De Miguel, F. Redi, J. Reich, F. Reiss, Z. Ren, P. K. Resmi, R. Ribatti, G. R. Ricart, D. Riccardi, S. Ricciardi, K. Richardson, M. Richardson-Slipper, K. Rinnert, P. Robbe, G. Robertson, E. Rodrigues, E. Rodriguez Fernandez, J. A. Rodriguez Lopez, E. Rodriguez Rodriguez, A. Rogovskiy, D. L. Rolf, P. Roloff, V. Romanovskiy, M. Romero Lamas, A. Romero Vidal, G. Romolini, F. Ronchetti, M. Rotondo, S. R. Roy, M. S. Rudolph, T. Ruf, M. Ruiz Diaz, R. A. Ruiz Fernandez, J. Ruiz Vidal, A. Ryzhikov, J. Ryzka, J. J. Saavedra Arias, J. J. Saborido Silva, R. Sadek, N. Sagidova, D. S. Sahoo, N. Sahoo, B. Saitta, M. Salomoni, C. Sanchez Gras, I. Sanderswood, R. Santacesaria, C. Santamarina Rios, M. Santimaria, L. Santoro, E. Santovetti, A. Saputi, D. Saranin, G. Sarpis, M. Sarpis, C. Satriano, A. Satta, M. Saur, D. Savrina, H. Sazak, L. G. Scantlebury Smead, A. Scarabotto, S. Schael, S. Scherl, M. Schiller, H. Schindler, M. Schmelling, B. Schmidt, S. Schmitt, H. Schmitz, O. Schneider, A. Schopper, N. Schulte, S. Schulte, M. H. Schune, R. Schwemmer, G. Schwering, B. Sciascia, A. Sciuccati, S. Sellam, A. Semennikov, T. Senger, M. Senghi Soares, A. Sergi, N. Serra, L. Sestini, A. Seuthe, Y. Shang, D. M. Shangase, M. Shapkin, R. S. Sharma, I. Shchemerov, L. Shchutska, T. Shears, L. Shekhtman, Z. Shen, S. Sheng, V. Shevchenko, B. Shi, Q. Shi, E. B. Shields, Y. Shimizu, E. Shmanin, R. Shorkin, J. D. Shupperd, R. Silva Coutinho, G. Simi, S. Simone, N. Skidmore, T. Skwarnicki, M. W. Slater, J. C. Smallwood, E. Smith, K. Smith, M. Smith, A. Snoch, L. Soares Lavra, M. D. Sokoloff, F. J. P. Soler, A. Solomin, A. Solovev, I. Solovyev, R. Song, Y. Song, Y. S. Song, F. L. Souza De Almeida, B. Souza De Paula, E. Spadaro Norella, E. Spedicato, J. G. Speer, E. Spiridenkov, P. Spradlin, V. Sriskaran, F. Stagni, M. Stahl, S. Stahl, S. Stanislaus, E. N. Stein, O. Steinkamp, O. Stenyakin, H. Stevens, D. Strekalina, Y. Su, F. Suljik, J. Sun, L. Sun, Y. Sun, D. S. Sundfeld Lima, W. Sutcliffe, P. N. Swallow, F. Swystun, A. Szabelski, T. Szumlak, Y. Tan, M. D. Tat, A. Terentev, F. Terzuoli, F. Teubert, E. Thomas, D. J. D. Thompson, H. Tilquin, V. Tisserand, S. T’Jampens, M. Tobin, L. Tomassetti, G. Tonani, X. Tong, D. Torres Machado, L. Toscano, D. Y. Tou, C. Trippl, G. Tuci, N. Tuning, L. H. Uecker, A. Ukleja, D. J. Unverzagt, E. Ursov, A. Usachov, A. Ustyuzhanin, U. Uwer, V. Vagnoni, A. Valassi, G. Valenti, N. Valls Canudas, H. Van Hecke, E. van Herwijnen, C. B. Van Hulse, R. Van Laak, M. van Veghel, G. Vasquez, R. Vazquez Gomez, P. Vazquez Regueiro, C. Vázquez Sierra, S. Vecchi, J. J. Velthuis, M. Veltri, A. Venkateswaran, M. Vesterinen, M. Vieites Diaz, X. Vilasis-Cardona, E. Vilella Figueras, A. Villa, P. Vincent, F. C. Volle, D. vom Bruch, N. Voropaev, K. Vos, G. Vouters, C. Vrahas, J. Walsh, E. J. Walton, G. Wan, C. Wang, G. Wang, J. Wang, M. Wang, N. W. Wang, R. Wang, X. Wang, X. W. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, J. Wendel, B. D. C. Westhenry, D. J. White, M. Whitehead, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: Branching fraction, Charm Physics, Hadron-Hadron Scattering, Spectroscopy, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract The decays of the B + meson to the final state D ∗ − D s + π + $$ {D}^{\ast -}{D}_s^{+}{\pi}^{+} $$ are studied in proton-proton collision data collected with the LHCb detector at centre-of-mass energies of 7, 8, and 13 TeV, corresponding to a total integrated luminosity of 9 fb −1. The ratio of branching fractions of the B + → D ∗ − D s + π + $$ {B}^{+}\to {D}^{\ast -}{D}_s^{+}{\pi}^{+} $$ and B 0 → D ∗ − D s + $$ {B}^0\to {D}^{\ast -}{D}_s^{+} $$ decays is measured to be 0.173 ± 0.006 ± 0.010, where the first uncertainty is statistical and the second is systematic. Using partially reconstructed D s ∗ + → D s + γ $$ {D}_s^{\ast +}\to {D}_s^{+}\gamma $$ and D s + π 0 $$ {D}_s^{+}{\pi}^0 $$ decays, the ratio of branching fractions between the B + → D ∗ − D s ∗ + π + $$ {B}^{+}\to {D}^{\ast -}{D}_s^{\ast +}{\pi}^{+} $$ and B + → D ∗ − D s + π + $$ {B}^{+}\to {D}^{\ast -}{D}_s^{+}{\pi}^{+} $$ decays is determined as 1.31 ± 0.07 ± 0.14. An amplitude analysis of the B + → D ∗ − D s + π + $$ {B}^{+}\to {D}^{\ast -}{D}_s^{+}{\pi}^{+} $$ decay is performed for the first time, revealing dominant contributions from known excited charm resonances decaying to the D *− π + final state. No significant evidence of exotic contributions in the D s + π + $$ {D}_s^{+}{\pi}^{+} $$ or D ∗ − D s + $$ {D}^{\ast -}{D}_s^{+} $$ channels is found. The fit fraction of the scalar state T c s ¯ 0 ∗ 2900 + + $$ {T}_{c\overline{s}0}^{\ast }{(2900)}^{++} $$ observed in the B + → D − D s + π + $$ {B}^{+}\to {D}^{-}{D}_s^{+}{\pi}^{+} $$ decay is determined to be less than 2.3% at a 90% confidence level.
Published: 2024
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31. Modelling the long-term health impact of COVID-19 using Graphical Chain Models

Author: K. Gourgoura, P. Rivadeneyra, E. Stanghellini, C. Caroni, F. Bartolucci, R. Curcio, S. Bartoli, R. Ferranti, I. Folletti, M. Cavallo, L. Sanesi, I. Dominioni, E. Santoni, G. Morgana, M. B. Pasticci, G. Pucci, and G. Vaudo
Subjects: COVID-19, Long COVID, Fatigue, Graphical Chain Model, Prevention, High resolution computed tomography, Infectious and parasitic diseases, RC109-216
Abstract: Abstract Background Long-term sequelae of SARS-CoV-2 infection, namely long COVID syndrome, affect about 10% of severe COVID-19 survivors. This condition includes several physical symptoms and objective measures of organ dysfunction resulting from a complex interaction between individual predisposing factors and the acute manifestation of disease. We aimed at describing the complexity of the relationship between long COVID symptoms and their predictors in a population of survivors of hospitalization for severe COVID-19-related pneumonia using a Graphical Chain Model (GCM). Methods 96 patients with severe COVID-19 hospitalized in a non-intensive ward at the “Santa Maria” University Hospital, Terni, Italy, were followed up at 3–6 months. Data regarding present and previous clinical status, drug treatment, findings recorded during the in-hospital phase, presence of symptoms and signs of organ damage at follow-up were collected. Static and dynamic cardiac and respiratory parameters were evaluated by resting pulmonary function test, echocardiography, high-resolution chest tomography (HRCT) and cardiopulmonary exercise testing (CPET). Results Twelve clinically most relevant factors were identified and partitioned into four ordered blocks in the GCM: block 1 - gender, smoking, age and body mass index (BMI); block 2 - admission to the intensive care unit (ICU) and length of follow-up in days; block 3 - peak oxygen consumption (VO2), forced expiratory volume at first second (FEV1), D-dimer levels, depression score and presence of fatigue; block 4 - HRCT pathological findings. Higher BMI and smoking had a significant impact on the probability of a patient’s admission to ICU. VO2 showed dependency on length of follow-up. FEV1 was related to the self-assessed indicator of fatigue, and, in turn, fatigue was significantly associated with the depression score. Notably, neither fatigue nor depression depended on variables in block 2, including length of follow-up. Conclusions The biological plausibility of the relationships between variables demonstrated by the GCM validates the efficacy of this approach as a valuable statistical tool for elucidating structural features, such as conditional dependencies and associations. This promising method holds potential for exploring the long-term health repercussions of COVID-19 by identifying predictive factors and establishing suitable therapeutic strategies.
Published: 2024
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32. Amplitude analysis of the radiative decay B s 0 $$ {\textrm{B}}_{\textrm{s}}^0 $$ → K+K − γ

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, H. Bao, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, M. Barnyakov, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, F. Baryshnikov, J. M. Basels, G. Bassi, B. Batsukh, A. Battig, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, M. J. Bradley, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, S. Calderon Ramirez, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, P. Camargo Magalhaes, J. I. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. Carcedo Salgado, R. Cardinale, A. Cardini, P. Carniti, L. Carus, A. Casais Vidal, R. Caspary, G. Casse, J. Castro Godinez, M. Cattaneo, G. Cavallero, V. Cavallini, S. Celani, D. Cervenkov, S. Cesare, A. J. Chadwick, I. Chahrour, M. Charles, Ph. Charpentier, C. A. Chavez Barajas, M. Chefdeville, C. Chen, S. Chen, Z. Chen, A. Chernov, S. Chernyshenko, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. Cifra, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Cocha Toapaxi, V. Coco, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, L. Congedo, A. Contu, N. Cooke, I. Corredoira, A. Correia, G. Corti, J. J. Cottee Meldrum, B. Couturier, D. C. Craik, M. Cruz Torres, E. Curras Rivera, R. Currie, C. L. Da Silva, S. Dadabaev, L. Dai, X. Dai, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, J. Daniel, A. Danilina, P. d’Argent, A. Davidson, J. E. Davies, A. Davis, O. De Aguiar Francisco, C. De Angelis, F. De Benedetti, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, S. Ek-In, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. Feng, M. Feo, M. Fernandez Gomez, A. D. Fernez, F. 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Leroy, T. Lesiak, B. Leverington, A. Li, H. Li, K. Li, L. Li, P. Li, P.-R. Li, Q. Li, S. Li, T. Li, Y. Li, Z. Lian, X. Liang, S. Libralon, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, K. Liu, S. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, C. Lucarelli, D. Lucchesi, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. M. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. 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Wang, X. Wang, X. W. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, J. Wendel, B. D. C. Westhenry, D. J. White, M. Whitehead, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: B Physics, Flavour Physics, Hadron-Hadron Scattering, Rare Decay, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract A search for radiative decay of B s 0 $$ {B}_s^0 $$ mesons to orbitally excited K + K − states is performed using proton proton collisions recorded by the LHCb experiment, corresponding to an integrated luminosity of 9 fb −1. The dikaon spectrum in the mass range m KK < 2400 MeV/c 2 is dominated by the ϕ(1020) resonance that accounts for almost 70% of the decay rate. Considering the possible contributions of f 2(1270), f 2 ′ $$ {f}_2^{\prime } $$ (1525) and f 2(2010) meson states, the overall tensor contribution to the amplitude is measured to be F f 2 = 16.8 ± 0.5 stat . ± 0.7 syst . % , $$ {\mathcal{F}}_{\left\{{f}_2\right\}}=16.8\pm 0.5\left(\textrm{stat}.\right)\pm 0.7\left(\textrm{syst}.\right)\%, $$ mostly dominated by the f 2 ′ $$ {f}_2^{\prime } $$ (1525) state. Several statistically equivalent solutions are obtained for the detailed resonant structure depending on whether the smaller amplitudes interfere destructively or constructively with the dominant amplitude. The preferred solution that corresponds to the lowest values of the fit fractions along with constructive interference leads to the relative branching ratio measurement B B s 0 → f 2 ′ γ B B s 0 → ϕγ = 19.4 − 0.8 + 0.9 stat . − 0.5 + 1.4 syst . ± 0.5 B % , $$ \frac{\mathcal{B}\left({B}_s^0\to {f}_2^{\prime}\gamma \right)}{\mathcal{B}\left({B}_s^0\to \phi \gamma \right)}={19.4}_{-0.8}^{+0.9}{\left(\textrm{stat}.\right)}_{-0.5}^{+1.4}\left(\textrm{syst}.\right)\pm 0.5\left(\mathcal{B}\right)\%, $$ where the last uncertainty is due to the ratio of measured branching fractions to the K + K − final state. This result represents the first observation of the radiative B s 0 → f 2 ′ 1525 γ $$ {B}_s^0\to {f}_2^{\prime }(1525)\gamma $$ decay, which is the second radiative transition observed in the B s 0 $$ {B}_s^0 $$ sector.
Published: 2024
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33. Study of b-hadron decays to Λ c + h − h ′ − $$ {\Lambda}_c^{+}{h}^{-}{h}^{\prime -} $$ final states

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, R. Ataide Da Silva, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, H. Bao, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, M. Barnyakov, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, J. M. Basels, G. Bassi, B. Batsukh, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, S. Calderon Ramirez, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, P. Camargo Magalhaes, J. I. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. Carcedo Salgado, R. Cardinale, A. Cardini, P. Carniti, L. Carus, A. Casais Vidal, R. Caspary, G. Casse, J. Castro Godinez, M. Cattaneo, G. Cavallero, V. Cavallini, S. Celani, D. Cervenkov, S. Cesare, A. J. Chadwick, I. Chahrour, M. Charles, Ph. Charpentier, E. Chatzianagnostou, C. A. Chavez Barajas, M. Chefdeville, C. Chen, S. Chen, Z. Chen, A. Chernov, S. Chernyshenko, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. Cifra, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Cocha Toapaxi, V. Coco, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, L. Congedo, A. Contu, N. Cooke, I. Corredoira, A. Correia, G. Corti, J. J. Cottee Meldrum, B. Couturier, D. C. Craik, M. Cruz Torres, E. Curras Rivera, R. Currie, C. L. Da Silva, S. Dadabaev, L. Dai, X. Dai, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, J. Daniel, A. Danilina, P. d’Argent, A. Davidson, J. E. Davies, A. Davis, O. De Aguiar Francisco, C. De Angelis, F. De Benedetti, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. Feng, M. Feo, A. Fernandez Casani, M. Fernandez Gomez, A. D. 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Lemos Cid, O. Leroy, T. Lesiak, B. Leverington, A. Li, H. Li, K. Li, L. Li, P. Li, P.-R. Li, Q. Li, S. Li, T. Li, Y. Li, Z. Lian, X. Liang, S. Libralon, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, K. Liu, S. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, C. Lucarelli, D. Lucchesi, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. J. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. Massafferri, R. Matev, A. Mathad, V. Matiunin, C. Matteuzzi, K. R. Mattioli, A. Mauri, E. Maurice, J. Mauricio, P. Mayencourt, J. Mazorra de Cos, M. Mazurek, M. McCann, L. Mcconnell, T. H. McGrath, N. T. McHugh, A. McNab, R. McNulty, B. Meadows, G. Meier, D. Melnychuk, F. M. Meng, M. Merk, A. Merli, L. Meyer Garcia, D. Miao, H. Miao, M. Mikhasenko, D. A. Milanes, A. Minotti, E. Minucci, T. Miralles, B. Mitreska, D. S. Mitzel, A. Modak, A. Mödden, R. A. Mohammed, R. D. Moise, S. Mokhnenko, T. Mombächer, M. Monk, S. Monteil, A. Morcillo Gomez, G. Morello, M. J. Morello, M. P. Morgenthaler, A. B. Morris, A. G. Morris, R. Mountain, H. Mu, Z. M. Mu, E. Muhammad, F. Muheim, M. Mulder, K. Müller, F. Muñoz-Rojas, R. Murta, P. Naik, T. Nakada, R. Nandakumar, T. Nanut, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, P. Neustroev, J. Nicolini, D. Nicotra, E. M. Niel, N. Nikitin, P. Nogarolli, P. Nogga, N. S. Nolte, C. Normand, J. Novoa Fernandez, G. Nowak, C. Nunez, H. N. Nur, A. Oblakowska-Mucha, V. Obraztsov, T. Oeser, S. Okamura, A. Okhotnikov, O. Okhrimenko, R. Oldeman, F. Oliva, M. Olocco, C. J. G. Onderwater, R. H. O’Neil, J. M. Otalora Goicochea, P. Owen, A. Oyanguren, O. Ozcelik, A. Padee, K. O. Padeken, B. Pagare, P. R. Pais, T. Pajero, A. Palano, M. Palutan, G. Panshin, L. Paolucci, A. Papanestis, M. Pappagallo, L. L. Pappalardo, C. Pappenheimer, C. Parkes, B. Passalacqua, G. Passaleva, D. Passaro, A. Pastore, M. Patel, J. Patoc, C. Patrignani, A. Paul, C. J. Pawley, A. Pellegrino, J. Peng, M. Pepe Altarelli, S. Perazzini, D. Pereima, H. Pereira Da Costa, A. Pereiro Castro, P. Perret, A. Perro, K. Petridis, A. Petrolini, J. P. Pfaller, H. Pham, L. Pica, M. Piccini, B. Pietrzyk, G. Pietrzyk, D. Pinci, F. Pisani, M. Pizzichemi, V. Placinta, M. Plo Casasus, T. Poeschl, F. Polci, M. Poli Lener, A. Poluektov, N. Polukhina, I. Polyakov, E. Polycarpo, S. Ponce, D. Popov, S. Poslavskii, K. Prasanth, C. Prouve, V. Pugatch, G. Punzi, S. Qasim, Q. Q. Qian, W. Qian, N. Qin, S. Qu, R. Quagliani, R. I. Rabadan Trejo, J. H. Rademacker, M. Rama, M. Ramírez García, V. Ramos De Oliveira, M. Ramos Pernas, M. S. Rangel, F. Ratnikov, G. Raven, M. Rebollo De Miguel, F. Redi, J. Reich, F. Reiss, Z. Ren, P. K. Resmi, R. Ribatti, G. R. Ricart, D. Riccardi, S. Ricciardi, K. Richardson, M. Richardson-Slipper, K. Rinnert, P. Robbe, G. Robertson, E. Rodrigues, E. Rodriguez Fernandez, J. A. Rodriguez Lopez, E. Rodriguez Rodriguez, A. Rogovskiy, D. L. Rolf, P. Roloff, V. Romanovskiy, M. Romero Lamas, A. Romero Vidal, G. Romolini, F. Ronchetti, T. Rong, M. Rotondo, S. R. Roy, M. S. Rudolph, T. Ruf, M. Ruiz Diaz, R. A. Ruiz Fernandez, J. Ruiz Vidal, A. Ryzhikov, J. Ryzka, J. J. Saavedra-Arias, J. J. Saborido Silva, R. Sadek, N. Sagidova, D. Sahoo, N. Sahoo, B. Saitta, M. Salomoni, C. Sanchez Gras, I. Sanderswood, R. Santacesaria, C. Santamarina Rios, M. Santimaria, L. Santoro, E. Santovetti, A. Saputi, D. Saranin, A. S. Sarnatskiy, G. Sarpis, M. Sarpis, C. Satriano, A. Satta, M. Saur, D. Savrina, H. Sazak, L. G. Scantlebury Smead, A. Scarabotto, S. Schael, S. Scherl, M. Schiller, H. Schindler, M. Schmelling, B. Schmidt, S. Schmitt, H. Schmitz, O. Schneider, A. Schopper, N. Schulte, S. Schulte, M. H. Schune, R. Schwemmer, G. Schwering, B. Sciascia, A. Sciuccati, S. Sellam, A. Semennikov, T. Senger, M. Senghi Soares, A. Sergi, N. Serra, L. Sestini, A. Seuthe, Y. Shang, D. M. Shangase, M. Shapkin, R. S. Sharma, I. Shchemerov, L. Shchutska, T. Shears, L. Shekhtman, Z. Shen, S. Sheng, V. Shevchenko, B. Shi, Q. Shi, Y. Shimizu, E. Shmanin, R. Shorkin, J. D. Shupperd, R. Silva Coutinho, G. Simi, S. Simone, N. Skidmore, T. Skwarnicki, M. W. Slater, J. C. Smallwood, E. Smith, K. Smith, M. Smith, A. Snoch, L. Soares Lavra, M. D. Sokoloff, F. J. P. Soler, A. Solomin, A. Solovev, I. Solovyev, R. Song, Y. Song, Y. S. Song, F. L. Souza De Almeida, B. Souza De Paula, E. Spadaro Norella, E. Spedicato, J. G. Speer, E. Spiridenkov, P. Spradlin, V. Sriskaran, F. Stagni, M. Stahl, S. Stahl, S. Stanislaus, E. N. Stein, O. Steinkamp, O. Stenyakin, H. Stevens, D. Strekalina, Y. Su, F. Suljik, J. Sun, L. Sun, Y. Sun, D. S. Sundfeld Lima, W. Sutcliffe, P. N. Swallow, F. Swystun, A. Szabelski, T. Szumlak, Y. Tan, M. D. Tat, A. Terentev, F. Terzuoli, F. Teubert, E. Thomas, D. J. D. Thompson, H. Tilquin, V. Tisserand, S. T’Jampens, M. Tobin, L. Tomassetti, G. Tonani, X. Tong, D. Torres Machado, L. Toscano, D. Y. Tou, C. Trippl, G. Tuci, N. Tuning, L. H. Uecker, A. Ukleja, D. J. Unverzagt, E. Ursov, A. Usachov, A. Ustyuzhanin, U. Uwer, V. Vagnoni, G. Valenti, N. Valls Canudas, H. Van Hecke, E. van Herwijnen, C. B. Van Hulse, R. Van Laak, M. van Veghel, G. Vasquez, R. Vazquez Gomez, P. Vazquez Regueiro, C. Vázquez Sierra, S. Vecchi, J. J. Velthuis, M. Veltri, A. Venkateswaran, M. Vesterinen, M. Vieites Diaz, X. Vilasis-Cardona, E. Vilella Figueras, A. Villa, P. Vincent, F. C. Volle, D. vom Bruch, N. Voropaev, K. Vos, G. Vouters, C. Vrahas, J. Wagner, J. Walsh, E. J. Walton, G. Wan, C. Wang, G. Wang, J. Wang, M. Wang, N. W. Wang, R. Wang, X. Wang, X. W. Wang, Y. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, J. Wendel, B. D. C. Westhenry, D. J. White, M. Whitehead, E. Whiter, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, K. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, C. Zeng, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, S. Z. Zheng, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: B Physics, Branching fraction, Hadron-Hadron Scattering, Heavy Quark Production, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract Decays of Ξ b − $$ {\Xi}_b^{-} $$ and Ω b − $$ {\Omega}_b^{-} $$ baryons to Λ c + h − h ′ − $$ {\Lambda}_c^{+}{h}^{-}{h}^{\prime -} $$ final states, with h − h ′− being π − π − , K − π − and K − K − meson pairs, are searched for using data collected with the LHCb detector. The data sample studied corresponds to an integrated luminosity of 8.7 fb −1 of pp collisions collected at centre-of-mass energies s $$ \sqrt{s} $$ = 7, 8 and 13 TeV. The products of the relative branching fractions and fragmentation fractions for each signal mode, relative to the B − → Λ c + p ¯ π − $$ {B}^{-}\to {\Lambda}_c^{+}\overline{p}{\pi}^{-} $$ mode, are measured, with Ξ b − → Λ c + K − π − $$ {\Xi}_b^{-}\to {\Lambda}_c^{+}{K}^{-}{\pi}^{-} $$ , Ξ b − → Λ c + K − K − $$ {\Xi}_b^{-}\to {\Lambda}_c^{+}{K}^{-}{K}^{-} $$ and Ω b − → Λ c + K − K − $$ {\varOmega}_b^{-}\to {\Lambda}_c^{+}{K}^{-}{K}^{-} $$ decays being observed at over 5 σ significance. The Ξ b − → Λ c + K − π − $$ {\Xi}_b^{-}\to {\Lambda}_c^{+}{K}^{-}{\pi}^{-} $$ mode is also used to measure the Ξ b − $$ {\Xi}_b^{-} $$ production asymmetry, which is found to be consistent with zero. In addition, the B − → Λ c + p ¯ K − $$ {B}^{-}\to {\Lambda}_c^{+}\overline{p}{K}^{-} $$ decay is observed for the first time, and its branching fraction is measured relative to that of the B − → Λ c + p ¯ π − $$ {B}^{-}\to {\Lambda}_c^{+}\overline{p}{\pi}^{-} $$ mode.
Published: 2024
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34. Connected smart elevator systems for smart power and time saving

Author: Ahmed Nabih Zaki Rashed, Manasa Yarrarapu, Ramachandran Thandaiah Prabu, Gnana Sagaya Raj Antony, Logashanmugam Edeswaran, E. Santosh Kumar, K. Aswitha, N. Snehith, and Shaik Hasane Ahammad
Subjects: Smart elevator, Deep learning, Power saving, Time-saving, Image processing, Floor prediction, Medicine, Science
Abstract: Abstract Smart elevators provide substantial promise for time and energy management applications by utilizing cutting edge artificial intelligence and image processing technology. In order to improve operating efficiency, this project designs an elevator system that uses the YOLO model for object detection. Compared to traditional methods, our results show a 15% improvement in wait times and a 20% reduction in energy use. Due to the elevator’s increased accuracy and dependability, users’ qualitative feedback shows a high degree of pleasure. These results imply that intelligent elevator systems can make a significant contribution to more intelligent building management. Due to the elevator’s increased accuracy and dependability, users’ qualitative feedback shows a high degree of pleasure. These results imply that intelligent elevator systems can make a significant contribution to more intelligent building management. The successful integration of artificial intelligence (AI) and image processing technologies in elevator systems presents a promising foundation for future research and development. Further advancements in object detection algorithms, such as refining YOLO models for even higher accuracy and real-time adaptability, hold potential to enhance operational efficiency. Integrating smart elevators more deeply into IoT networks and building management systems could enable comprehensive energy management strategies and real-time decision-making. Predictive maintenance models tailored to elevator components could minimize downtime and optimize service schedules, enhancing overall reliability. Additionally, exploring adaptive user interfaces and personalized scheduling algorithms could further elevate user satisfaction by tailoring elevator interactions to individual preferences. Sustainable practices, including energy-efficient designs and integration of renewable energy sources, represent crucial avenues for reducing environmental impact. Addressing security concerns through advanced encryption and access control mechanisms will be essential for safeguarding sensitive data in smart elevator systems.
Published: 2024
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35. Tracking of charged particles with nanosecond lifetimes at LHCb

Author: LHCb Collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, J. A. Adams, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, H. Bao, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, M. Barnyakov, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, F. Baryshnikov, J. M. Basels, G. Bassi, B. Batsukh, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, M. J. Bradley, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, S. Calderon Ramirez, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, P. Camargo Magalhaes, J. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. Carcedo Salgado, R. Cardinale, A. Cardini, P. Carniti, L. Carus, A. Casais Vidal, R. Caspary, G. Casse, J. Castro Godinez, M. Cattaneo, G. Cavallero, V. Cavallini, S. Celani, D. Cervenkov, S. Cesare, A. J. Chadwick, I. Chahrour, M. Charles, Ph. Charpentier, C. A. Chavez Barajas, M. Chefdeville, C. Chen, S. Chen, Z. Chen, A. Chernov, S. Chernyshenko, V. Chobanova, S. Cholak, M. Chrzaszcz, A. Chubykin, V. Chulikov, P. Ciambrone, X. Cid Vidal, G. Ciezarek, P. Cifra, P. E. L. Clarke, M. Clemencic, H. V. Cliff, J. Closier, C. Cocha Toapaxi, V. Coco, J. Cogan, E. Cogneras, L. Cojocariu, P. Collins, T. Colombo, A. Comerma-Montells, L. Congedo, A. Contu, N. Cooke, I. Corredoira, A. Correia, G. Corti, J. J. Cottee Meldrum, B. Couturier, D. C. Craik, M. Cruz Torres, E. Curras Rivera, R. Currie, C. L. Da Silva, S. Dadabaev, L. Dai, X. Dai, E. Dall’Occo, J. Dalseno, C. D’Ambrosio, J. Daniel, A. Danilina, P. d’Argent, A. Davidson, J. E. Davies, A. Davis, O. De Aguiar Francisco, C. De Angelis, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. Feng, M. Feo, M. Fernandez Gomez, A. D. Fernez, F. Ferrari, F. Ferreira Rodrigues, M. Ferrillo, M. Ferro-Luzzi, S. Filippov, R. A. Fini, M. Fiorini, K. M. Fischer, D. S. Fitzgerald, C. Fitzpatrick, F. Fleuret, M. Fontana, L. F. Foreman, R. Forty, D. Foulds-Holt, M. Franco Sevilla, M. Frank, E. Franzoso, G. Frau, C. Frei, D. A. Friday, J. Fu, Q. Fuehring, Y. Fujii, T. Fulghesu, E. Gabriel, G. Galati, M. D. Galati, A. Gallas Torreira, D. Galli, S. Gambetta, M. Gandelman, P. Gandini, B. Ganie, H. Gao, R. Gao, Y. Gao, M. Garau, L. M. Garcia Martin, P. Garcia Moreno, J. García Pardiñas, K. G. Garg, L. Garrido, C. Gaspar, R. E. Geertsema, L. L. Gerken, E. Gersabeck, M. Gersabeck, T. Gershon, Z. Ghorbanimoghaddam, L. Giambastiani, F. I. Giasemis, V. Gibson, H. K. Giemza, A. L. Gilman, M. Giovannetti, A. Gioventù, P. Gironella Gironell, C. Giugliano, M. A. Giza, E. L. Gkougkousis, F. C. Glaser, V. V. Gligorov, C. Göbel, E. Golobardes, D. Golubkov, A. Golutvin, A. Gomes, S. Gomez Fernandez, F. Goncalves Abrantes, M. Goncerz, G. Gong, J. A. Gooding, I. V. Gorelov, C. Gotti, J. P. Grabowski, L. A. Granado Cardoso, E. Graugés, E. Graverini, L. Grazette, G. Graziani, A. T. Grecu, L. M. Greeven, N. A. Grieser, L. Grillo, S. Gromov, C. Gu, M. Guarise, M. Guittiere, V. Guliaeva, P. A. Günther, A.-K. Guseinov, E. Gushchin, Y. Guz, T. Gys, K. Habermann, T. Hadavizadeh, C. Hadjivasiliou, G. Haefeli, C. Haen, J. Haimberger, M. Hajheidari, M. M. Halvorsen, P. M. Hamilton, J. Hammerich, Q. Han, X. Han, S. Hansmann-Menzemer, L. Hao, N. Harnew, M. Hartmann, J. He, P. H. Hein Nogarolli Vilela Pereira, F. Hemmer, C. Henderson, R. D. L. Henderson, A. M. Hennequin, K. Hennessy, L. Henry, J. Herd, J. Herdieckerhoff, P. Herrero Gascon, J. Heuel, A. Hicheur, G. Hijano Mendizabal, D. Hill, S. E. Hollitt, J. Horswill, R. Hou, Y. Hou, N. Howarth, J. Hu, W. Hu, X. Hu, W. Huang, W. Hulsbergen, R. J. Hunter, M. Hushchyn, D. Hutchcroft, D. Ilin, P. Ilten, A. Inglessi, A. Iniukhin, A. Ishteev, K. Ivshin, R. Jacobsson, H. Jage, S. J. Jaimes Elles, S. Jakobsen, E. Jans, B. K. Jashal, A. Jawahery, V. Jevtic, E. Jiang, X. Jiang, Y. Jiang, Y. J. Jiang, M. John, D. Johnson, C. R. Jones, T. P. Jones, S. Joshi, B. Jost, N. Jurik, I. Juszczak, D. Kaminaris, S. Kandybei, Y. Kang, C. Kar, M. Karacson, D. Karpenkov, A. M. Kauniskangas, J. W. Kautz, F. Keizer, M. Kenzie, T. Ketel, B. Khanji, A. Kharisova, S. Kholodenko, G. Khreich, T. Kirn, V. S. Kirsebom, O. Kitouni, S. Klaver, N. Kleijne, K. Klimaszewski, M. R. Kmiec, S. Koliiev, L. Kolk, A. Konoplyannikov, P. Kopciewicz, P. Koppenburg, M. Korolev, I. Kostiuk, O. Kot, S. Kotriakhova, A. Kozachuk, P. Kravchenko, L. Kravchuk, M. Kreps, P. Krokovny, W. Krupa, W. Krzemien, O. K. Kshyvanskyi, J. Kubat, S. Kubis, M. Kucharczyk, V. Kudryavtsev, E. Kulikova, A. Kupsc, B. K. Kutsenko, D. Lacarrere, A. Lai, A. Lampis, D. Lancierini, C. Landesa Gomez, J. J. Lane, R. Lane, C. Langenbruch, J. Langer, O. Lantwin, T. Latham, F. Lazzari, C. Lazzeroni, R. Le Gac, R. Lefèvre, A. Leflat, S. Legotin, M. Lehuraux, E. Lemos Cid, O. Leroy, T. Lesiak, B. Leverington, A. Li, H. Li, K. Li, L. Li, P. Li, P.-R. Li, Q. Li, S. Li, T. Li, Y. Li, Z. Lian, X. Liang, S. Libralon, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, K. Liu, S. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, C. Lucarelli, D. Lucchesi, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. M. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. M. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. 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W. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, J. Wendel, B. D. C. Westhenry, D. J. White, M. Whitehead, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, C. Zeng, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract A method is presented to reconstruct charged particles with lifetimes between $$10\,\text {ps} $$ 10 ps and $$10\,\text {ns},$$ 10 ns , which considers a combination of their decay products and the partial tracks created by the initial charged particle. Using the $${\varXi } ^- $$ Ξ - baryon as a benchmark, the method is demonstrated with simulated events and proton-proton collision data at $$\sqrt{s} =13\,\text {TeV},$$ s = 13 TeV , corresponding to an integrated luminosity of 2.0 $$\,\text {fb} ^{-1}$$ fb - 1 collected with the LHCb detector in 2018. Significant improvements in the angular resolution and the signal purity are obtained. The method is implemented as part of the LHCb Run 3 event trigger in a set of requirements to select detached hyperons. This is the first demonstration of the applicability of this approach at the LHC, and the first to show its scaling with instantaneous luminosity.
Published: 2024
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36. First observation of the Λ b 0 $$ {\Lambda}_b^0 $$ → D + D − Λ decay

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, J. A. Adams, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, F. Baryshnikov, J. M. Basels, G. Bassi, B. Batsukh, A. Battig, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, A. Beiter, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, C. Bertella, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, M. J. Bradley, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Bursche, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, J. I. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. 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De Aguiar Francisco, C. De Angelis, F. De Benedetti, J. de Boer, K. De Bruyn, S. De Capua, M. De Cian, U. De Freitas Carneiro Da Graca, E. De Lucia, J. M. De Miranda, L. De Paula, M. De Serio, D. De Simone, P. De Simone, F. De Vellis, J. A. de Vries, F. Debernardis, D. Decamp, V. Dedu, L. Del Buono, B. Delaney, H.-P. Dembinski, J. Deng, V. Denysenko, O. Deschamps, F. Dettori, B. Dey, P. Di Nezza, I. Diachkov, S. Didenko, S. Ding, L. Dittmann, V. Dobishuk, A. D. Docheva, A. Dolmatov, C. Dong, A. M. Donohoe, F. Dordei, A. C. dos Reis, A. D. Dowling, A. G. Downes, W. Duan, P. Duda, M. W. Dudek, L. Dufour, V. Duk, P. Durante, M. M. Duras, J. M. Durham, O. D. Durmus, A. Dziurda, A. Dzyuba, S. Easo, E. Eckstein, U. Egede, A. Egorychev, V. Egorychev, S. Eisenhardt, E. Ejopu, S. Ek-In, L. Eklund, M. Elashri, J. Ellbracht, S. Ely, A. Ene, E. Epple, S. Escher, J. Eschle, S. Esen, T. Evans, F. Fabiano, L. N. Falcao, Y. Fan, B. Fang, L. Fantini, M. Faria, K. Farmer, D. Fazzini, L. Felkowski, M. 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Subjects: B Physics, Branching fraction, Flavour Physics, Hadron-Hadron Scattering, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract The Λ b 0 $$ {\Lambda}_b^0 $$ → D + D − Λ decay is observed for the first time using proton-proton collision data collected by the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 5.3 fb −1. Using the B 0 → D + D − K S 0 $$ {D}^{+}{D}^{-}{K}_S^0 $$ decay as a reference channel, the product of the relative production cross-section and decay branching fractions is measured to be R = σ Λ b 0 σ B 0 = B Λ b 0 → D + D − Λ B B 0 → D + D − K S 0 = 0.179 ± 0.022 ± 0.014 , $$ \mathcal{R}=\frac{\sigma_{\Lambda_b^0}}{\sigma_{B^0}}=\frac{\mathcal{B}\left({\Lambda}_b^0\to {D}^{+}{D}^{-}\Lambda \right)}{\mathcal{B}\left({B}^0\to {D}^{+}{D}^{-}{K}_{\textrm{S}}^0\right)}=0.179\pm 0.022\pm 0.014, $$ where the first uncertainty is statistical and the second is systematic. The known branching fraction of the reference channel, B B 0 → D + D − K S 0 $$ \mathcal{B}\left({B}^0\to {D}^{+}{D}^{-}{K}_{\textrm{S}}^0\right) $$ , and the cross-section ratio, σ Λ b 0 / σ B 0 $$ {\sigma}_{\Lambda_b^0}/{\sigma}_{B^0} $$ , previously measured by LHCb are used to derive the branching fraction of the Λ b 0 $$ {\Lambda}_b^0 $$ → D + D − Λ decay B Λ b 0 → D + D − Λ = 1.24 ± 0.15 ± 0.10 ± 0.28 ± 0.11 × 10 − 4 , $$ \mathcal{B}\left({\Lambda}_b^0\to {D}^{+}{D}^{-}\Lambda \right)=\left(1.24\pm 0.15\pm 0.10\pm 0.28\pm 0.11\right)\times {10}^{-4}, $$ where the third and fourth contributions are due to uncertainties of B B 0 → D + D − K S 0 $$ \mathcal{B}\left({B}^0\to {D}^{+}{D}^{-}{K}_{\textrm{S}}^0\right) $$ and σ Λ b 0 / σ B 0 $$ {\sigma}_{\Lambda_b^0}/{\sigma}_{B^0} $$ , respectively. Inspection of the D +Λ and D + D − invariant-mass distributions suggests a rich presence of intermediate resonances in the decay. The Λ b 0 $$ {\Lambda}_b^0 $$ → D *+ D − Λ decay is also observed for the first time as a partially reconstructed component in the D + D − Λ invariant mass spectrum.
Published: 2024
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37. Search for the B s 0 $$ {B}_s^0 $$ → μ + μ − γ decay

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, A. A. Adefisoye, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, F. Baryshnikov, J. M. Basels, G. Bassi, B. Batsukh, A. Battig, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, A. Beiter, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, C. Bertella, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, T. Blake, F. Blanc, J. E. Blank, S. Blusk, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, M. J. Bradley, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, E. Buchanan, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Bursche, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, J. I. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. Capriotti, R. Caravaca-Mora, A. Carbone, L. 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Walton, G. Wan, C. Wang, G. Wang, J. Wang, M. Wang, N. W. Wang, R. Wang, X. Wang, X. W. Wang, Y. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, B. D. C. Westhenry, D. J. White, M. Whitehead, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, X. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: B Physics, Flavour Physics, Hadron-Hadron Scattering, Rare Decay, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract A search for the fully reconstructed B s 0 $$ {B}_s^0 $$ → μ + μ − γ decay is performed at the LHCb experiment using proton-proton collisions at s $$ \sqrt{s} $$ = 13 TeV corresponding to an integrated luminosity of 5.4 fb −1. No significant signal is found and upper limits on the branching fraction in intervals of the dimuon mass are set B B s 0 → μ + μ − γ < 4.2 × 10 − 8 , m μ + μ − ∈ 2 m μ 1.70 GeV / c 2 , B B s 0 → μ + μ − γ < 7.7 × 10 − 8 , m μ + μ − ∈ 1.70, 2.88 GeV / c 2 , B B s 0 → μ + μ − γ < 4.2 × 10 − 8 , m μ + μ − ∈ 3.92 m B s 0 GeV / c 2 , $$ {\displaystyle \begin{array}{cc}\mathcal{B}\left({B}_s^0\to {\mu}^{+}{\mu}^{-}\gamma \right)
Published: 2024
Full Text: View/download PDF

38. Amplitude analysis of the Λ b 0 → pK − γ $$ {\Lambda}_{\textrm{b}}^0\to {\textrm{pK}}^{-}\upgamma $$ decay

Author: The LHCb collaboration, R. Aaij, A. S. W. Abdelmotteleb, C. Abellan Beteta, F. Abudinén, T. Ackernley, B. Adeva, M. Adinolfi, P. Adlarson, C. Agapopoulou, C. A. Aidala, Z. Ajaltouni, S. Akar, K. Akiba, P. Albicocco, J. Albrecht, F. Alessio, M. Alexander, A. Alfonso Albero, Z. Aliouche, P. Alvarez Cartelle, R. Amalric, S. Amato, J. L. Amey, Y. Amhis, L. An, L. Anderlini, M. Andersson, A. Andreianov, P. Andreola, M. Andreotti, D. Andreou, A. Anelli, D. Ao, F. Archilli, M. Argenton, S. Arguedas Cuendis, A. Artamonov, M. Artuso, E. Aslanides, M. Atzeni, B. Audurier, D. Bacher, I. Bachiller Perea, S. Bachmann, M. Bachmayer, J. J. Back, P. Baladron Rodriguez, V. Balagura, W. Baldini, J. Baptista de Souza Leite, M. Barbetti, I. R. Barbosa, R. J. Barlow, S. Barsuk, W. Barter, M. Bartolini, J. Bartz, F. Baryshnikov, J. M. Basels, G. Bassi, B. Batsukh, A. Battig, A. Bay, A. Beck, M. Becker, F. Bedeschi, I. B. Bediaga, A. Beiter, S. Belin, V. Bellee, K. Belous, I. Belov, I. Belyaev, G. Benane, G. Bencivenni, E. Ben-Haim, A. Berezhnoy, R. Bernet, S. Bernet Andres, H. C. Bernstein, C. Bertella, A. Bertolin, C. Betancourt, F. Betti, J. Bex, Ia. Bezshyiko, J. Bhom, M. S. Bieker, N. V. Biesuz, P. Billoir, A. Biolchini, M. Birch, F. C. R. Bishop, A. Bitadze, A. Bizzeti, M. P. Blago, T. Blake, F. Blanc, J. E. Blank, S. Blusk, D. Bobulska, V. Bocharnikov, J. A. Boelhauve, O. Boente Garcia, T. Boettcher, A. Bohare, A. Boldyrev, C. S. Bolognani, R. Bolzonella, N. Bondar, F. Borgato, S. Borghi, M. Borsato, J. T. Borsuk, S. A. Bouchiba, T. J. V. Bowcock, A. Boyer, C. Bozzi, M. J. Bradley, S. Braun, A. Brea Rodriguez, N. Breer, J. Brodzicka, A. Brossa Gonzalo, J. Brown, D. Brundu, A. Buonaura, L. Buonincontri, A. T. Burke, C. Burr, A. Bursche, A. Butkevich, J. S. Butter, J. Buytaert, W. Byczynski, S. Cadeddu, H. Cai, R. Calabrese, L. Calefice, S. Cali, M. Calvi, M. Calvo Gomez, J. Cambon Bouzas, P. Campana, D. H. Campora Perez, A. F. Campoverde Quezada, S. Capelli, L. 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Lacarrere, A. Lai, A. Lampis, D. Lancierini, C. Landesa Gomez, J. J. Lane, R. Lane, C. Langenbruch, J. Langer, O. Lantwin, T. Latham, F. Lazzari, C. Lazzeroni, R. Le Gac, S. H. Lee, R. Lefèvre, A. Leflat, S. Legotin, M. Lehuraux, O. Leroy, T. Lesiak, B. Leverington, A. Li, H. Li, K. Li, L. Li, P. Li, P.-R. Li, S. Li, T. Li, Y. Li, Z. Li, Z. Lian, X. Liang, C. Lin, T. Lin, R. Lindner, V. Lisovskyi, R. Litvinov, F. L. Liu, G. Liu, H. Liu, K. Liu, Q. Liu, S. Liu, Y. Liu, Y. L. Liu, A. Lobo Salvia, A. Loi, J. Lomba Castro, T. Long, J. H. Lopes, A. Lopez Huertas, S. López Soliño, G. H. Lovell, C. Lucarelli, D. Lucchesi, S. Luchuk, M. Lucio Martinez, V. Lukashenko, Y. Luo, A. Lupato, E. Luppi, K. Lynch, X.-R. Lyu, G. M. Ma, R. Ma, S. Maccolini, F. Machefert, F. Maciuc, B. M. Mack, I. Mackay, L. M. Mackey, L. R. Madhan Mohan, M. M. Madurai, A. Maevskiy, D. Magdalinski, D. Maisuzenko, M. W. Majewski, J. J. Malczewski, S. Malde, B. Malecki, L. Malentacca, A. Malinin, T. Maltsev, G. Manca, G. Mancinelli, C. Mancuso, R. Manera Escalero, D. Manuzzi, D. Marangotto, J. F. Marchand, R. Marchevski, U. Marconi, S. Mariani, C. Marin Benito, J. Marks, A. M. Marshall, P. J. Marshall, G. Martelli, G. Martellotti, L. Martinazzoli, M. Martinelli, D. Martinez Santos, F. Martinez Vidal, A. Massafferri, M. Materok, R. Matev, A. Mathad, V. Matiunin, C. Matteuzzi, K. R. Mattioli, A. Mauri, E. Maurice, J. Mauricio, P. Mayencourt, M. Mazurek, M. McCann, L. Mcconnell, T. H. McGrath, N. T. McHugh, A. McNab, R. McNulty, B. Meadows, G. Meier, D. Melnychuk, M. Merk, A. Merli, L. Meyer Garcia, D. Miao, H. Miao, M. Mikhasenko, D. A. Milanes, A. Minotti, E. Minucci, T. Miralles, S. E. Mitchell, B. Mitreska, D. S. Mitzel, A. Modak, A. Mödden, R. A. Mohammed, R. D. Moise, S. Mokhnenko, T. Mombächer, M. Monk, I. A. Monroy, S. Monteil, A. Morcillo Gomez, G. Morello, M. J. Morello, M. P. Morgenthaler, J. Moron, A. B. Morris, A. G. Morris, R. Mountain, H. Mu, Z. M. Mu, E. Muhammad, F. Muheim, M. Mulder, K. Müller, F. Muñoz-Rojas, R. Murta, P. Naik, T. Nakada, R. Nandakumar, T. Nanut, I. Nasteva, M. Needham, N. Neri, S. Neubert, N. Neufeld, P. Neustroev, R. Newcombe, J. Nicolini, D. Nicotra, E. M. Niel, N. Nikitin, P. Nogga, N. S. Nolte, C. Normand, J. Novoa Fernandez, G. Nowak, C. Nunez, H. N. Nur, A. Oblakowska-Mucha, V. Obraztsov, T. Oeser, S. Okamura, R. Oldeman, F. Oliva, M. Olocco, C. J. G. Onderwater, R. H. O’Neil, J. M. Otalora Goicochea, T. Ovsiannikova, P. Owen, A. Oyanguren, O. Ozcelik, K. O. Padeken, B. Pagare, P. R. Pais, T. Pajero, A. Palano, M. Palutan, G. Panshin, L. Paolucci, A. Papanestis, M. Pappagallo, L. L. Pappalardo, C. Pappenheimer, C. Parkes, B. Passalacqua, G. Passaleva, D. Passaro, A. Pastore, M. Patel, J. Patoc, C. Patrignani, C. J. Pawley, A. Pellegrino, M. Pepe Altarelli, S. Perazzini, D. Pereima, A. Pereiro Castro, P. Perret, A. Perro, K. Petridis, A. Petrolini, S. Petrucci, J. P. Pfaller, H. Pham, L. Pica, M. Piccini, B. Pietrzyk, G. Pietrzyk, D. Pinci, F. Pisani, M. Pizzichemi, V. Placinta, M. Plo Casasus, F. Polci, M. Poli Lener, A. Poluektov, N. Polukhina, I. Polyakov, E. Polycarpo, S. Ponce, D. Popov, S. Poslavskii, K. Prasanth, C. Prouve, V. Pugatch, G. Punzi, W. Qian, N. Qin, S. Qu, R. Quagliani, R. I. Rabadan Trejo, B. Rachwal, J. H. Rademacker, M. Rama, M. Ramírez García, M. Ramos Pernas, M. S. Rangel, F. Ratnikov, G. Raven, M. Rebollo De Miguel, F. Redi, J. Reich, F. Reiss, Z. Ren, P. K. Resmi, R. Ribatti, G. R. Ricart, D. Riccardi, S. Ricciardi, K. Richardson, M. Richardson-Slipper, K. Rinnert, P. Robbe, G. Robertson, E. Rodrigues, E. Rodriguez Fernandez, J. A. Rodriguez Lopez, E. Rodriguez Rodriguez, A. Rogovskiy, D. L. Rolf, A. Rollings, P. Roloff, V. Romanovskiy, M. Romero Lamas, A. Romero Vidal, G. Romolini, F. Ronchetti, M. Rotondo, S. R. Roy, M. S. Rudolph, T. Ruf, M. Ruiz Diaz, R. A. Ruiz Fernandez, J. Ruiz Vidal, A. Ryzhikov, J. Ryzka, J. J. Saborido Silva, R. Sadek, N. Sagidova, N. Sahoo, B. Saitta, M. Salomoni, C. Sanchez Gras, I. Sanderswood, R. Santacesaria, C. Santamarina Rios, M. Santimaria, L. Santoro, E. Santovetti, A. Saputi, D. Saranin, G. Sarpis, M. Sarpis, A. Sarti, C. Satriano, A. Satta, M. Saur, D. Savrina, H. Sazak, L. G. Scantlebury Smead, A. Scarabotto, S. Schael, S. Scherl, A. M. Schertz, M. Schiller, H. Schindler, M. Schmelling, B. Schmidt, S. Schmitt, H. Schmitz, O. Schneider, A. Schopper, N. Schulte, S. Schulte, M. H. Schune, R. Schwemmer, G. Schwering, B. Sciascia, A. Sciuccati, S. Sellam, A. Semennikov, M. Senghi Soares, A. Sergi, N. Serra, L. Sestini, A. Seuthe, Y. Shang, D. M. Shangase, M. Shapkin, R. S. Sharma, I. Shchemerov, L. Shchutska, T. Shears, L. Shekhtman, Z. Shen, S. Sheng, V. Shevchenko, B. Shi, E. B. Shields, Y. Shimizu, E. Shmanin, R. Shorkin, J. D. Shupperd, R. Silva Coutinho, G. Simi, S. Simone, N. Skidmore, R. Skuza, T. Skwarnicki, M. W. Slater, J. C. Smallwood, E. Smith, K. Smith, M. Smith, A. Snoch, L. Soares Lavra, M. D. Sokoloff, F. J. P. Soler, A. Solomin, A. Solovev, I. Solovyev, R. Song, Y. Song, Y. S. Song, F. L. Souza De Almeida, B. Souza De Paula, E. Spadaro Norella, E. Spedicato, J. G. Speer, E. Spiridenkov, P. Spradlin, V. Sriskaran, F. Stagni, M. Stahl, S. Stahl, S. Stanislaus, E. N. Stein, O. Steinkamp, O. Stenyakin, H. Stevens, D. Strekalina, Y. Su, F. Suljik, J. Sun, L. Sun, Y. Sun, P. N. Swallow, K. Swientek, F. Swystun, A. Szabelski, T. Szumlak, M. Szymanski, Y. Tan, S. Taneja, M. D. Tat, A. Terentev, F. Terzuoli, F. Teubert, E. Thomas, D. J. D. Thompson, H. Tilquin, V. Tisserand, S. T’Jampens, M. Tobin, L. Tomassetti, G. Tonani, X. Tong, D. Torres Machado, L. Toscano, D. Y. Tou, C. Trippl, G. Tuci, N. Tuning, L. H. Uecker, A. Ukleja, D. J. Unverzagt, E. Ursov, A. Usachov, A. Ustyuzhanin, U. Uwer, V. Vagnoni, A. Valassi, G. Valenti, N. Valls Canudas, H. Van Hecke, E. van Herwijnen, C. B. Van Hulse, R. Van Laak, M. van Veghel, R. Vazquez Gomez, P. Vazquez Regueiro, C. Vázquez Sierra, S. Vecchi, J. J. Velthuis, M. Veltri, A. Venkateswaran, M. Vesterinen, M. Vieites Diaz, X. Vilasis-Cardona, E. Vilella Figueras, A. Villa, P. Vincent, F. C. Volle, D. vom Bruch, V. Vorobyev, N. Voropaev, K. Vos, G. Vouters, C. Vrahas, J. Walsh, E. J. Walton, G. Wan, C. Wang, G. Wang, J. Wang, M. Wang, N. W. Wang, R. Wang, X. Wang, X. W. Wang, Y. Wang, Z. Wang, J. A. Ward, M. Waterlaat, N. K. Watson, D. Websdale, Y. Wei, B. D. C. Westhenry, D. J. White, M. Whitehead, A. R. Wiederhold, D. Wiedner, G. Wilkinson, M. K. Wilkinson, M. Williams, M. R. J. Williams, R. Williams, F. F. Wilson, W. Wislicki, M. Witek, L. Witola, C. P. Wong, G. Wormser, S. A. Wotton, H. Wu, J. Wu, Y. Wu, K. Wyllie, S. Xian, Z. Xiang, Y. Xie, A. Xu, J. Xu, L. Xu, M. Xu, Z. Xu, D. Yang, S. Yang, X. Yang, Y. Yang, Z. Yang, V. Yeroshenko, H. Yeung, H. Yin, C. Y. Yu, J. Yu, X. Yuan, E. Zaffaroni, M. Zavertyaev, M. Zdybal, M. Zeng, C. Zhang, D. Zhang, J. Zhang, L. Zhang, S. Zhang, Y. Zhang, Y. Z. Zhang, Y. Zhao, A. Zharkova, A. Zhelezov, X. Z. Zheng, Y. Zheng, T. Zhou, X. Zhou, Y. Zhou, V. Zhovkovska, L. Z. Zhu, X. Zhu, Z. Zhu, V. Zhukov, J. Zhuo, Q. Zou, D. Zuliani, and G. Zunica
Subjects: Flavour Physics, Particle and Resonance Production, Rare Decay, Hadron-Hadron Scattering, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract The resonant structure of the radiative decay Λ b 0 → pK − γ $$ {\Lambda}_b^0\to {pK}^{-}\gamma $$ in the region of proton-kaon invariant-mass up to 2.5 GeV/c 2 is studied using proton-proton collision data recorded at centre-of-mass energies of 7, 8, and 13 TeV collected with the LHCb detector, corresponding to a total integrated luminosity of 9 fb −1. Results are given in terms of fit and interference fractions between the different components contributing to this final state. Only Λ resonances decaying to pK − are found to be relevant, where the largest contributions stem from the Λ(1520), Λ(1600), Λ(1800), and Λ(1890) states.
Published: 2024
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39. Novel, Edible Melanin-Protein-Based Bioactive Films for Cheeses: Antimicrobial, Mechanical and Chemical Characteristics

Author: Ana Rita Ferraz, Manuela Goulão, Christophe E. Santo, Ofélia Anjos, Maria Luísa Serralheiro, and Cristina M. B. S. Pintado
Subjects: cheese, whey protein isolate, bioactive coatings, melanin, edible packing, Health (social science), Plant Science, Health Professions (miscellaneous), Microbiology, Food Science
Abstract: The cheese rind is the natural food packaging of cheese and is subject to a wide range of external factors that compromise the appearance of the cheese, including color defects caused by spoilage microorganisms. First, eight films based on whey protein isolate (WPI) coatings were studied, of which IS3CA (WPI 5% + sorbitol 3% + citric acid 3%) was selected for presenting better properties. From the IS3CA film, novel films containing melanin M1 (74 µg/mL) and M2 (500 µg/mL) were developed and applied to cheese under proof-of-concept and industrial conditions. After 40 days of maturation, M2 presented the lowest microorganism count for all the microbial parameters analyzed. The cheese with M2 showed the lowest lightness, which indicates that it is the darkest cheese due to the melanin concentration. It was found that the mechanical and colorimetric properties are the ones that contribute the most to the distinction of the M2 film in cheese from the others. Using FTIR-ATR, it was possible to distinguish the rinds of M2 cheeses because they contained the highest concentrations of melanin. Thus, this study shows that the film with M2 showed the best mechanical, chemical and antimicrobial properties for application in cheese.
Published: 2023

40. Unraveling the drivers of plant taxonomic and phylogenetic β-diversity in a human-modified tropical dry forest

Author: Inara R. Leal, Kátia F. Rito, Víctor Arroyo-Rodríguez, Edgar E. Santo-Silva, Jeannine Cavender-Bares, Gustavo Souza, and Marcelo Tabarelli
Subjects: 0106 biological sciences, Tropical and subtropical dry broadleaf forests, Ecology, Phylogenetic tree, 010604 marine biology & hydrobiology, Rare species, Biodiversity, Biology, 010603 evolutionary biology, 01 natural sciences, Ecological resilience, Disturbance (ecology), Ecosystem, human activities, Ecology, Evolution, Behavior and Systematics, Nature and Landscape Conservation, Woody plant
Abstract: Biodiversity maintenance in human-modified landscapes largely depends on spatial variations in species composition (β-diversity), but the impact of human disturbance on β-diversity remains poorly understood. We examined how taxonomic and phylogenetic β-diversity of woody plant communities in the Brazilian Caatinga dry forest respond to two emerging threats—chronic anthropogenic disturbance and water scarcity. We separately assessed diversity metrics that give a disproportionate weight to rare species, and metrics weighted by dominant species. We recorded a total of 5118 individuals from 104 species across 19 0.1-ha plots into a 21,430-ha human-modified landscape exposed to chronic disturbances and a high variation in climatic water deficit. At the landscape scale, β-diversity was higher when considering rare species than when focusing on dominant species, especially for the phylogenetic dimension of β-diversity. Water deficit was the primary driver of plant taxonomic and phylogenetic β-diversity, followed by the number of cattle and inter-site isolation; however, rare species seem to depend more strongly on these factors than the dominant ones. Therefore, preserving as much forest as possible, including areas exposed to different disturbance level and climate variables, is critical to prevent the loss of rare species and maintain the compositional differentiation of biotic assemblages. Such forest cover should be maintained in a large number of forest patches scattered through the landscape to preserve biologically and functionally distinct components of this ecosystem, avoid landscape-scale biotic homogenization, and thus favor its ecological resilience.
Published: 2021

41. Multidimensional redox potential/pKa coupling in multicopper oxidases from molecular dynamics: implications for the proton transfer mechanism

Author: Gustavo Troiano Feliciano, Anderson A. E. Santo, Vitor Hugo Rangel Lazaroti, and Universidade Estadual Paulista (UNESP)
Subjects: Chemistry, General Physics and Astronomy, Protonation, Photochemistry, Porphyrin, Redox, Catalysis, Metal, chemistry.chemical_compound, Molecular dynamics, Oxidation state, visual_art, visual_art.visual_art_medium, Molecule, Physical and Theoretical Chemistry
Abstract: Made available in DSpace on 2022-04-28T19:48:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-28 Bilirubin oxidases (BOD) are metalloenzymes that catalyze the conversion of O2and bilirubin to biliverdin and water in the metabolism of chlorophyll and porphyrin. In this work we have used the CpHMD method to analyze the effects of the different oxidation states on the BOD trinuclear cluster (TNC). Our results demonstrate that there is a link between the different oxidation states of copper ions and the protonation capacity of nearby titratable residues. Each configuration affects pKadifferently, creating proton gradients within the enzyme that act in an extremely orderly manner. This order is closely linked to the catalytic mechanism and leads us to the conclusion of the entry of the O2molecule and its reduction in water molecules is associated with the probability of the release of protons from nearby acid groups. With this information, we deduce that under the initial reaction conditions the acidic side chains of nearby residues can be protonated; this allows the enzyme to reduce the activation energy of the reaction by coupling the proton transfer to oxidation state changes in the metallic center. Enginerring Physics and Mathematics Department São Paulo State University (Unesp) Institute of Chemistry Enginerring Physics and Mathematics Department São Paulo State University (Unesp) Institute of Chemistry
Published: 2021

42. COCONUT FIBER SENSOR FOR HUMIDITY / SENSOR DE FIBRA DE COCO PARA HUMIDADE

Author: Celso Carlino Fornari, Jorge Sales, Klezio Darlain E. Santo, and G. S. Amarante-Segundo
Subjects: Marketing, Pharmacology, Polyester resin, chemistry.chemical_classification, Organizational Behavior and Human Resource Management, Materials science, Strategy and Management, Pharmaceutical Science, Humidity, chemistry.chemical_element, Adsorption, Electrical resistance and conductance, chemistry, Drug Discovery, Deposition (phase transition), Graphite, Fiber, Composite material, Carbon
Abstract: In this article we present the construction of a resistive humidity sensor making use of alternative materials of organic origin and source of renewable, coconut fiber. The hygroscopic film is obtained by deposition of the coconut fiber powder combined with carbon powder (graphite) on a substrate of polyester resin with short coconut fiber. Experimental results indicated that the sensor has characteristics expected from a humidity sensor, with adsorption in the time range of 45 seconds and variation in electrical resistance depending on the amount of water molecules in the air.
Published: 2021

43. NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis

Author: Franck Vandermoere, Tiago M. Bandeiras, Ana C. F. Paiva, Edouard Bertrand, Bruno Charpentier, Xavier Manival, Céline Verheggen, Marie-Eve Chagot, Pedro M. F. Sousa, Marc Quinternet, Marie-Cécile Robert, Philippe Fort, Paulo E. Santo, Jonathan Bizarro, Yoann Abel, Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Instituto de Biologia Experimental e Tecnológica (IBET), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Ingénierie, Biologie et Santé en Lorraine (IBSLor), Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de Génomique Fonctionnelle (IGF), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche en Biologie Cellulaire (CRBM), Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Université Montpellier 1 (UM1), CNRS, Université de Montpellier (UM), Université de Lorraine (UL), ANR, Ligue Nationale contre le cancer, Institut National du cancer, ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche en Biologie cellulaire de Montpellier (CRBM), Verheggen, Céline, and Développment d'une infrastructure française distribuée coordonnée - - France-BioImaging2010 - ANR-10-INBS-0004 - INBS - VALID
Subjects: Proteomics, Saccharomyces cerevisiae Proteins, AcademicSubjects/SCI00010, Recombinant Fusion Proteins, [SDV]Life Sciences [q-bio], ATPase, Mutant, Chaperone, Cofactor, Gene Knockout Techniques, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Protein Domains, Genes, Reporter, Ribonucleoproteins, Small Nucleolar, Protein Interaction Mapping, RNA and RNA-protein complexes, Genetics, Humans, RNP biogenesis, HSP90 Heat-Shock Proteins, Small nucleolar RNA, Eye Proteins, 030304 developmental biology, Multi-subunit complex assembly, 0303 health sciences, PAQosome, biology, DNA Helicases, Nuclear Proteins, Box C/D snoRNP, Hsp90, AAA proteins, Cell biology, [SDV] Life Sciences [q-bio], Multiprotein Complexes, Chaperone (protein), biology.protein, ATPases Associated with Diverse Cellular Activities, Carrier Proteins, 030217 neurology & neurosurgery, Biogenesis, HeLa Cells, Molecular Chaperones
Abstract: The PAQosome is a large complex composed of the HSP90/R2TP chaperone and a prefoldin-like module. It promotes the biogenesis of cellular machineries but it is unclear how it discriminates closely related client proteins. Among the main PAQosome clients are C/D snoRNPs and in particular their core protein NOP58. Using NOP58 mutants and proteomic experiments, we identify different assembly intermediates and show that C12ORF45, which we rename NOPCHAP1, acts as a bridge between NOP58 and PAQosome. NOPCHAP1 makes direct physical interactions with the CC-NOP domain of NOP58 and domain II of RUVBL1/2 AAA+ ATPases. Interestingly, NOPCHAP1 interaction with RUVBL1/2 is disrupted upon ATP binding. Moreover, while it robustly binds both yeast and human NOP58, it makes little interactions with NOP56 and PRPF31, two other closely related CC-NOP proteins. Expression of NOP58, but not NOP56 or PRPF31, is decreased in NOPCHAP1 KO cells. We propose that NOPCHAP1 is a client-loading PAQosome cofactor that selects NOP58 to promote box C/D snoRNP assembly.
Published: 2020

44. A Rare Case of Invasive Sarcomatoid Mesothelioma Causing Spontaneous Tumor Lysis Syndrome and Shock

Author: E. Santo, A. Deengar, and M. Zutler
Published: 2022

45. Dysfunctional glymphatic system with disrupted aquaporin-4 expression pattern on astrocytes causes bacterial product accumulation in the CSF during pneumococcal meningitis

Author: Jaqueline S. Generoso, Sigrun Thorsdottir, Allan Collodel, Diogo Dominguini, Roberta R. E. Santo, Fabricia Petronilho, Tatiana Barichello, and Federico Iovino
Abstract: BackgroundPneumococcal meningitis, inflammation of the meninges due to an infection of the Central Nervous System caused by Streptococcus pneumoniae (the pneumococcus), is the most common form of community-acquired bacterial meningitis globally. The brain is separated from the systemic circulation by the blood-brain barrier (BBB), and meningitis triggers the host immune response increasing the BBB permeability, allowing peripheral immune cells to reach the cerebrospinal fluid (CSF), and increasing debris production. The glymphatic system is a glial-dependent clearance pathway that drives the exchange of compounds between the brain parenchyma and the CSF regulating the waste clearance away from the brain. Aquaporin-4 (AQP4)-water channels on astrocytic end feet regulate the solute transport of the glymphatic system.MethodsWistar rats, either subjected to pneumococcal meningitis or to artificial-CSF (sham), received Evans blue albumin (EBA) intracisternal. Overall, the meningitis group presented a significant impairment of the glymphatic system by retaining the EBA in the brain without consistently releasing the EBA into the bloodstream compared to the sham non-infected group. Through western blot and immunofluorescence microscopy analysis using rat CSF and brain tissue sections, an increased accumulation of pneumococci was detected over time in the CSF, and because of a loss of drainage between CSF and brain interstitial space, such bacterial accumulation was not observed in the brain parenchyma. Western blot analysis for Iba1, TMEM119 and IFN-Ɣ in rat brain homogenates and NSE in serum showed increased neuroinflammation and neuronal damage in the brain over time during pneumococcal infection. Neurological impairment upon neuronal cell damage caused by meningitis with a malfunctioning glymphatic system was also demonstrated through open-field behavioral tests comparing rats from sham and meningitis groups. Lastly, protein expression analysis of AQP4 revealed no differences in AQP4 between the brains of the rats from the meningitis group and those from the sham non-infected rats. Importantly, confocal microscopy analysis showed a detachment of the astrocytic end feet from the BBB vascular endothelium with consequent misplacement of AQP4-water channels.ConclusionsThese findings clearly indicate that pneumococcal meningitis decreases the glymphatic system’s functionality, increasing the neurotoxic waste debris in the brain ultimately leading to brain-wide neuroinflammation and neuronal damage. Finally, our results clearly showed that during pneumococcal meningitis, the glymphatic system does not function because of a detachment of the astrocytic end feet from the BBB vascular endothelium, which leads to a misplacement of AQP4 with consequent the loss of the AQP4-water channel’s functionality.
Published: 2022

46. Urban Soil Safety Policies: The Next Frontier for Mitigating Lead Exposures and Promoting Sustainable Food Production

Author: Sara N. Lupolt, Raychel E. Santo, Brent F. Kim, Thomas A. Burke, and Keeve E. Nachman
Subjects: Global and Planetary Change, environmental justice, soil safety, exposure, policy, lead, urban agriculture, Epidemiology, Health, Toxicology and Mutagenesis, Public Health, Environmental and Occupational Health, Management, Monitoring, Policy and Law, Pollution, Waste Management and Disposal, Water Science and Technology
Abstract: Urban soils bear the persistent legacy of leaded gasoline and past industrial practices. Soil safety policies (SSPs) are an important public health tool with the potential to inform, identify, and mitigate potential health risks faced by urban growers, but little is known about how these policies may protect growers from exposures to lead and other soil contaminants. We reviewed and evaluated 43 urban agriculture (UA) policies in 40 US cities pertaining to soil safety. About half of these cities had a least one SSP that offered recommendations or provided services for soil testing. Eight cities had at least one SSP containing a requirement pertaining to any topic (e.g., soil testing, a specific best practice for growing). We found notable inconsistencies across SSPs for “acceptable” levels of lead in soils and the activities and behaviors recommended at each level. We specify research needed to inform revisions to US Environmental Protection Agency guidance for lead in soils specific to UA. We conclude with a series of recommendations to guide the development or revision of SSPs.
Published: 2022

47. Patient-derived ovarian cancer explants: preserved viability and histopathological features in long-term agitation-based cultures

Author: Rita Mendes, Teresa F. Mendes, Marta Teixeira, Vítor E. Santo, Catarina Brito, Sofia Abreu, Fernanda Silva, Erwin R. Boghaert, and Ana Félix
Subjects: Cancer microenvironment, Adult, Cell type, Time Factors, Cell Survival, Cell Culture Techniques, lcsh:Medicine, Antineoplastic Agents, Drug resistance, Biology, Article, Immune system, Lymphocytes, Tumor-Infiltrating, Ovarian cancer, Ovarian carcinoma, medicine, Tumor Cells, Cultured, Chemotherapy, Humans, Cancer models, lcsh:Science, Aged, Aged, 80 and over, Ovarian Neoplasms, Multidisciplinary, lcsh:R, Cancer, Epithelial Cells, Fibroblasts, Middle Aged, medicine.disease, Cancer therapeutic resistance, Ki-67 Antigen, Apoptosis, Cancer research, Female, lcsh:Q, Explant culture
Abstract: Ovarian carcinoma (OvC) remains a major therapeutic challenge due to its propensity to develop resistance after an initial response to chemotherapy. Interactions of tumour cells with the surrounding microenvironment play a role in tumour survival, invasion capacity and drug resistance. Cancer models that retain tissue architecture and tumour microenvironment components are therefore essential to understand drug response and resistance mechanisms. Herein, our goal was to develop a long-term OvC patient-derived explant (OvC-PDE) culture strategy in which architecture and cell type heterogeneity of the original tumour would be retained. Samples from 25 patients with distinct OvC types and one with a benign tumour, were cultured for 30 days in agitation-based culture systems with 100% success rate. OvC-PDE cultures retained the original tumour architecture and main cellular components: epithelial cells, fibroblasts and immune cells. Epithelial cells kept their original levels of proliferation and apoptosis. Moreover, the major extracellular components, such as collagen-I and -IV, were retained in explants. OvC-PDE cultures were exposed to standard-of-care chemotherapeutics agents for 2 weeks, attesting the ability of the platform for drug assays employing cyclic drug exposure regimens. We established an OvC-PDE dynamic culture in which tumour architecture and cell type heterogeneity were preserved for the different OvC types, replicating features of the original tumour and compatible with long-term drug exposure for drug efficacy and resistance studies.
Published: 2020

48. An archaeology of French scenography: staging the excavation of a collective imagination

Author: Carolina E. Santo
Subjects: Visual Arts and Performing Arts, media_common.quotation_subject, Architecture, Scenography, Art history, Excavation, Art, Research process, media_common
Abstract: This article reports and reflects on the artistic research process of Excavating the Remains of French Scenography in Prague presented at the site-specific performance festival for the Prague Quadr...
Published: 2020

49. The palmSyagrus coronataproliferates and structures vascular epiphyte assemblages in a human-modified landscape of the Caatinga dry forest

Author: Maria Fabíola Barros, Kátia F. Rito, Leila J.B. Gonçalves, Inara R. Leal, Edgar E. Santo-Silva, and Marcelo Tabarelli
Subjects: Intermediate Disturbance Hypothesis, biology, Habitat, Disturbance (ecology), Ecology, Biodiversity, Plant community, Epiphyte, Syagrus coronata, biology.organism_classification, Ecology, Evolution, Behavior and Systematics, Global biodiversity
Abstract: The proliferation of disturbance-adapted species in human-modified landscapes may change the structure of plant communities, but the response of biodiversity to human disturbances remains poorly understood. We examine the proliferation of the palm,Syagrus coronata, in disturbed forest stands and its impacts on the structure of vascular epiphyte assemblages in a human-modified landscape of Brazilian Caatinga dry forest. First, we comparedS. coronatadensity between old-growth and regenerating forest stands. We then surveyed vascular epiphytes on 680 phorophytes (S. coronataand non-palm/control species) across five habitat types with different disturbance levels. There was an eight-fold increase inS. coronatadensity in regenerating areas compared with in old-growth forest.Syagrus coronotasupported richer epiphyte assemblages at local (i.e. per palm) and landscape (i.e. pooling all palms) scale than control phorophytes, supporting more than 11 times the number of species of control phorophytes at both scales. Epiphyte assemblages were more abundant, species-rich and dominated by abiotically dispersed species in forest sites with intermediate disturbance levels (regenerating forest stands). More than simply operating as an exclusive phorophyte for more than 90% of the epiphyte species we recorded here,S. coronatafavours epiphyte persistence and structures their assemblages across human-modified landscapes of the Caatinga forest.
Published: 2020

50. Challenging an IoT platform to address new services in a flexible grid

Author: Aurélio Blanquet, Bruno E. Santo, João Basílio, António Pratas, Mário Guerreiro, Clara Gouveia, David Rua, Ricardo Bessa, António Carrapatoso, Everton Alves, André Madureira, Gil Sampaio, and Luís Seca
Subjects: General Medicine
Published: 2020

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