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Aim . To assess the efficacy of physical cardiorehabilitation in patients with acute coronary syndrome non-ST-elevation (NSTEACS) and percutaneous coronary intervention (PCI) on infarction-relevant artery. Material and methods . To the prospective study, 35 patients included — mean age 57,9±9,7 y.o.; 78% males, 22% females after NSTEACS with urgent PCI on symptom-dependent artery and noncomplicated post-surgery period. Time of inclusion into the study was 2-8 weeks after ACS onset. At 1 and 12 weeks of cardiorehabilitation programs there was functional (echocardiography, electrocardiography, exercise testing) and laboratory diagnostics (lipids and chemistry). For 12 weeks the participants visited 3 times per weeks the standard cardorehabilitation trainings. Results . After the cardiorehabilitation course, in patients we found decreae of total cholesterol from 4,4±1,4 to 3,9±1,1 (р=0,02); low density lipoproteides level from 2,6±1,1 to 2,1±0,7 (р=0,002); significant increase of high density lipoproteides from 0,9±0,3 to 1,2±0,4 min (р

Echocardiographic parameters were assessed in patients with non-ST segment elevation acute coronary syndrome, who underwent emergency percutaneous coronary intervention followed by various outpatient physical cardiac rehabilitation programs. The patients underwent physical rehabilitation for 3 months under conditions of diagnostic centre in the rehabilitation unit according to the standard program including in treadmill or bicycle exercise in the exercise therapy room or with Nordic walking in the main training block. After rehabilitation course, the left ventricular mass index significantly decreased and systolic volume and left ventricular ejection fraction significantly increased in both groups. Nordic walking training for 3 months non-ST segment elevation acute coronary syndrome induced similar positive shifts in the parameters of intracardiac hemodynamics, as standard treadmill or bicycle training program, which allows considering it as an alternative cardiac rehabilitation method.

Цель. Оценить клиническую эффективность реабилитации у пациентов с острым коронарным синдромом без подъема сегмента ST (ОКСбпST), перенесших экстренное чрескожное коронарное вмешательство (ЧКВ) на симптом-связанной артерии, с помощью нагрузочного тестирования до и после реабилитации методом скандинавской ходьбы (СХ). Материал и методы. В проспективное исследование были включены 34 пациента (средний возраст 58,5±8,6 года; 76% мужчин), перенесших ОКСбпST с экстренным ЧКВ на симптом-связанной артерии и неосложненным течением послеоперационного периода. Пациенты 12 нед посещали 3-разовые занятия СХ в отделении реабилитации. Структура тренировки включала 15-минутную разминку, упражнения выполнялись со специальными палками, последующим 30-45-минутным аэробным блоком СХ (3 мин - 25% от пороговой мощности; 30-45 мин - 50-60% от пороговой мощности; 5 мин - 30% от пороговой мощности) и заключительную 10-минутную растяжку. Всем пациентам до начала и после завершения курса физической реабилитации было проведено нагрузочное тестирование (тредмил, стандартный протокол Брюса) с оценкой следующих параметров: частота сердечных сокращений (ЧСС) и артериальное давление (АД) в покое, на фоне физической нагрузки (ФН) и в периоде восстановления; время восстановления ЧСС и АД; длительность ФН (мин), толерантность к физической нагрузке (МЕТ). Результаты. У пациентов после курса реабилитации отмечено: достоверное снижение средней величины ЧСС покоя (с 74,5±11,1 до 71,5±10,9 уд/мин; p=0,04); достоверное увеличение толерантности к ФН (с 3,9±0,9 до 5,0±1,7 МЕТ; p

To evaluate the diagnostic capabilities of cardiac magnetic resonance imaging (MRI) in patients with inflammatory cardiomyopathy (ICMP) and to compare its results with endomyocardial biopsy (EMB) data and clinical and laboratory parameters.Cardiac MRI was performed using the "Lake Louise Criteria" in 51 patients with ICMP and a 4.1 +/- 3.4-year history of chronic heart failure (CHF). EMB was carried out in 25 patients. Their clinical state was evaluated by the results of a 6-minute walk test and by a clinical assessment scale; N-terminal pro-brain natriuretic peptide levels were estimated. All the patients received the recommended therapy for CHF.Myocardial areas of delayed enhancement were found in 20 (39%) patients. Myocardial edema or early contrast enhancement was not recorded in any case. An immunohistological study revealed myocardial inflammation in 12 (48%) patients. Six patients with chronic myocarditis and 4 patients without myocarditis had delayed-phase contrast enhancement areas. There was a statistically significant correlation of the contrast-enhanced myocardial volume with the frequency of single and paired ventricular premature beats (r = 0.66; p = 0.002 and r = 0.54; p = 0.01). CONCLUSION; The patients with delayed enhancement are at high risk of ventricular tachycardia. The severity of CHF is uncorrelated with the contrast-enhanced myocardial volume. Delayed enhancement is unrelated to the activity of myocardial inflammation, as evidenced by the immunohistological study.