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Objective of the study is to summarize long-term data on the dynamics of areal and abundance rates of the prairie tick, D. reticulatus in the territory of the Tula Region. Materials and methods. Processed and reviewed have been literature sources, archive documents, and results of personal observations over a period of 1949–2013. Applied have been computer-based software products Google Earth, MapInfo Professional v. 11.5. wrapped in GIS Software Package. Results and conclusions. It is determined that over the last decade D. reticulatus has been found not only in the forest and adjacent western forest-steppe zone, but also in the eastern and south-eastern forest-steppe area. Specified have been the territories with uniformly high density of population and sparse distribution of D. reticulatus ticks. It is established that nowadays abundance rates of the ticks show no substantial differences both in the forestmeadow areas of the forest zone, and similar areas of the forest-steppe zone. Identified has been correlation between the nature of F. tularensis culture isolation from D. reticulatus and intensity of epizootic process of tularemia infection, which allows for in-time targeted epizootiological survey and regulation of preventive activities.

Based on the analysis of the information concerning distribution and abundance of Ixodidae ticks in the territory of the Tula Region (1998-2012), obtained have been the new data on the expansion of I. ricinus habitat. Results of phyto-geographical zoning of the region have served as a landscape base for investigation of regularities as regards spatial distribution of the species. Specified have been the territories with low, medium, and high population density rate. Biotopes with the most favorable environmental conditions for the species are situated in the mixed woods of the Prioksky region and broad-leaved forests - of the Zasechny one. As for the forest-steppe areas, optimum biotopes are localized in the highland and steppificated oakwoods in the south of South-Eastern Region. Thus it has been established that in the recent decade I. ricinus ticks can be found not only in the forest areas, but in the forest-steppe ones too. This may be related to the increase in their numbers under favorable environmental conditions, reduction of farming lands, and shrub invasion. Average value for I. ricinus numbers in the forest area reaches 39.4 specimen/flag-kilometer; in the forest-steppe zone - 23.7 specimen/flag-kilometer. Identified have been potentially hazardous territories as regards natural-focal tick-borne infections, the agent circulation and transmission of which is sustained by I. ricinus. The finding in its turn sets the grounds for carrying out specific epizootiological surveillance and regulation of preventive measures.

Despite the large arsenal of analgetics acting through different pharmacological mechanisms and the development of various anesthesia methods, the problem of postoperative pain treatment still remains urgent. Providing a complete pain relief after a surgery remains a desired, but not always a reachable goal. According to the literature, 30 to 75% of patients undergoing surgery suffer from the severe pain syndrome in the postoperative period. This article presents the experience with the use of a prolonged intravenous infusion of Dexmedetomidine as a part of multimodal analgesia in patients who underwent endoprosthetic replacement of large joints.

Over the recent years, an increasing attention has been paid in the Russian healthcare to the concept of afast-track surgery also known as enhanced recovery after surgery (ERAS). This article presents the advantage of inhalation anesthetic agents from the perspective of the ERAS concept. A special attention is paid to drugs belonging to halogen-containing inhalation anesthetic class (Sevoflurane and Desflurane). It is emphasized that, despite a number of differences in the clinical effect of these anesthetics, they are drugs of choice in the fast-track surgery.