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Your search keyword '"E. Bouliong-Pillai"' showing total 3 results
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3 results on '"E. Bouliong-Pillai"'

1. 580 POSTER RhoA and RhoB inversly modulate estrogen receptor alpha expression and transcriptional activities in breast cancer cell lines

Author

George C. Prendergast, Y. Bergé, P. Balaguer, Gilles Favre, F. Dalenc, E. Meunier, S. Doisneau-Sixou, E. Malissein, and E. Bouliong-Pillai

Subjects
Cancer Research, Estrogen-related receptor alpha, RHOA, Oncology, Breast cancer cell line, biology, RHOB, Cancer research, biology.protein, Estrogen receptor, Estrogen receptor alpha, Estrogen receptor beta
Published
2008

2. RhoB controls estrogen receptor target genes expression through a modulation of ER recruitment on the promoter binding sites, in MCF- 7 cells

Author

Sophie F. Doisneau-Sixou, Emilie Malissein, Patrick Balaguer, Elise Meunier, E. Bouliong-Pillai, Gilles Favre, Florence Dalenc, Isabelle Lajoie-Mazenc, and Yann Berge

Subjects
Cancer Research, Estrogen-related receptor alpha, Oncology, MCF-7, Chemistry, RHOB, Cancer research, Estrogen receptor, Estrogen-related receptor gamma, Binding site, Estrogen receptor alpha, Estrogen receptor beta
Published
2008

3. Clinical stem-cell sources contain CD8+CD3+ T-cell receptor-negative cells that facilitate bone marrow repopulation with hematopoietic stem cells.

Author

Bridenbaugh S, Kenins L, Bouliong-Pillai E, Kalberer CP, Shklovskaya E, Gratwohl A, and Wodnar-Filipowicz A

Subjects
Animals, Bone Marrow Cells metabolism, Cell Differentiation, Hematopoietic Stem Cells metabolism, Humans, Mice, Receptors, Antigen, T-Cell immunology, Receptors, Antigen, T-Cell metabolism, Bone Marrow Cells cytology, Bone Marrow Cells immunology, CD3 Complex metabolism, CD8-Positive T-Lymphocytes immunology, CD8-Positive T-Lymphocytes metabolism, Hematopoietic Stem Cells cytology, Hematopoietic Stem Cells immunology
Abstract

Clinical observations in patients undergoing bone marrow transplantation implicate the involvement of CD8(+) cells in promoting the stem-cell engraftment process. These findings are supported by mouse transplant studies, which attributed the engraftment-facilitating function to subpopulations of murine CD8(+) cells, but the analogous cells in humans have not been identified. Here, we report that clinical stem-cell grafts contain a population of CD8alpha(+)CD3epsilon(+) T-cell receptor- negative cells with an engraftment facilitating function, named candidate facilitating cells (cFCs). Purified cFC augmented human hematopoiesis in NOD/SCID mice receiving suboptimal doses of human CD34(+) cells. In vitro, cFCs cocultured with CD34(+) cells increased hematopoietic colony formation, suggesting a direct effect on clonogenic precursors. These results provide evidence for the existence of rare human CD8(+)CD3(+)TCR(-) cells with engraftment facilitating properties, the adoptive transfer of which could improve the therapeutic outcome of stem-cell transplantation.

Published
2008
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