10 results on '"E., Pacaud"'
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2. Upper-limit on the Advanced Virgo output mode cleaner cavity length noise
- Author
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Romain Gouaty, A. Masserot, Frédérique Marion, Marine Ducrot, E. Pacaud, B. Mours, Romain Bonnand, M. Was, and L. Rolland
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Physics ,Physics - Instrumentation and Detectors ,Physics and Astronomy (miscellaneous) ,010308 nuclear & particles physics ,Gravitational wave ,business.industry ,Detector ,Resonance ,Order (ring theory) ,FOS: Physical sciences ,Port (circuit theory) ,Instrumentation and Detectors (physics.ins-det) ,General Relativity and Quantum Cosmology (gr-qc) ,01 natural sciences ,General Relativity and Quantum Cosmology ,Optics ,0103 physical sciences ,Limit (music) ,Radio frequency ,010306 general physics ,business ,Noise (radio) - Abstract
The Advanced Virgo detector uses two monolithic optical cavities at its output port to suppress higher order modes and radio frequency sidebands from the carrier light used for gravitational wave detection. These two cavities in series form the output mode cleaner. We present a measured upper limit on the length noise of these cavities that is consistent with the thermo-refractive noise prediction of $8 \times 10^{-16}\,\textrm{m/Hz}^{1/2}$ at 15 Hz. The cavity length is controlled using Peltier cells and piezo-electric actuators to maintain resonance on the incoming light. A length lock precision of $3.5 \times 10^{-13}\,\textrm{m}$ is achieved. These two results are combined to demonstrate that the broadband length noise of the output mode cleaner in the 10-60 Hz band is at least a factor 10 below other expected noise sources in the Advanced Virgo detector design configuration., 10 pages, 4 figures, accepted by CQG
- Published
- 2017
3. Virgo: a laser interferometer to detect gravitational waves
- Author
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Tjeerd Ketel, Antonio Eleuteri, M. Parisi, R. Passaquieti, L. Di Fiore, B. Mours, A. Królak, M. Blom, F. Beauville, K. G. Arun, G. A. Prodi, R. DeSalvo, M. Barsuglia, Gianpietro Cagnoli, Gianluca Persichetti, V. Granata, Julien Moreau, B. Mansoux, D. Verkindt, G. Losurdo, Anna Dari, M. Doets, B. Canuel, F. Piergiovanni, G. Ballardin, T Maiani, L. Giacobone, Y. Minenkov, M. Pietka, Patrice Hello, E. Turri, X Grave, R. Morand, L. Bonelli, M. Davier, G. Pagliaroli, I. Maksimovic, J. Marque, R. L. Ward, R. Hermel, G. Hemming, A. Masserot, Marco G. Tarallo, F. Vetrano, M. A. Mazzoni, L. Journet, O Lodygensky, J. P. Zendri, F. Nocera, G. Vedovato, V. Loriette, G. Barrand, P. N. Y. David, István Rácz, D. Boget, Ludovico Carbone, P. Popolizio, C Drezen, D. Passuello, C. Palomba, V Reita, Piotr Jaranowski, J.-M. Mackowski, Antoine Heidmann, Lisa Barsotti, Riccardo Sturani, Shourov Chatterji, Sofiane Aoudia, C. Arnault, Fausto Acernese, Andreas Freise, A. Di Virgilio, A. Giazotto, F. Mul, Alessandra Toncelli, G. Parguez, L. Brocco, Claude Boccara, J-Y. Vinet, I. Ferrante, S. Hamdani, R. Sottile, F. Cleva, M. Mantovani, Samuele Cortese, C Garnier, M. Lorenzini, V. Dattilo, S. D'Antonio, T. Bouedo, F. Travasso, R. Gouaty, Michał Bejger, Alessandra Corsi, L. Giordano, Mauro Tonelli, L. A. Forte, A. Dietz, M. Alshourbagy, M. Granata, L. Derome, L. Fabbroni, E. Genin, G. Cella, R. Bilhaut, L. Taffarello, A. Grado, J. L. Beney, B Dujardin, V. Fafone, R. Del Fabbro, M. Punturo, Andrea Chincarini, G. Gemme, M. Drago, P. Amico, P. Ganau, M. Galimberti, P. La Penna, F. Raffaelli, Eric Hennes, A. Pasqualetti, M. G. Beker, S. Petit, M. Pichot, Enrico Calloni, N. Liguori, L. Salconi, O. Veziant, V. Re, Guido Russo, Mirko Prato, C. Bradaschia, M. Dehamme, G. De Carolis, P. Dominici, L Matone, L. Holloway, F. Antonucci, Saverio Avino, O. Francois, A. Chiummo, Luca Gammaitoni, A. Paoli, F. Moreau, N. Leroy, B. L. Swinkels, F. Marion, F. Ricci, B. Dulach, D. Sentenac, G. Debreczeni, B. Lagrange, P. Puppo, Maurizio Ripepe, R. Paoletti, M. Loupias, F. Fidecaro, G. M. Guidi, E. Chassande-Mottin, S. Kreckelbergh, M. E. Gáspár, B. Lieunard, V. Moscatelli, K. Yamamoto, A. Brillet, M. Del Prete, Igor Neri, N. Letendre, L. Bosi, B. Bouhou, L. Pinard, C. Girard, T. Accadia, L. Naticchioni, Salvatore Vitale, M Laval, H Voet, F. Richard, P. Astone, M. Perciballi, Tania Regimbau, S. Frasca, M. Branchesi, R. Cavalieri, H. J. Bulten, L. Massonnet, L. Palladino, R. De Rosa, V. Malvezzi, A. Colla, A. Morgia, F. Frasconi, A. Basti, J. F. J. van den Brand, R. Flaminio, S. Birindelli, Tenglin Li, Archana Pai, F. Paoletti, P. Ruggi, S. Mancini, M. Iannarelli, S. Braccini, M. Tacca, D. Babusci, J.-P. Coulon, D. Jehanno, B. Sassolas, J. C. Lacotte, A Dominjon, L. Sperandio, A. C. Clapson, G. Conforto, F. Garufi, A. Viceré, H Groenstege, Andrea Gaddi, J.-D. Fournier, L. Rolland, Fabrizio Barone, C. Buy, I. Kowalska, Marie-Anne Bizouard, M. Bebronne, J. Franc, C. Michel, N. Morgado, J. C. Le Marec, V Sannibale, J. Colas, Ettore Majorana, G. Gennaro, P. Marin, M. Yvert, A. Rocchi, C. Eder, E. Campagna, P. Roudier, Fabio Marchesoni, R. Taddei, N. Arnaud, G. Daguin, J. L. Montorio, I. Fiori, R Pignard, R. Day, V. Boschi, Luisa Bracci, Roberto Cecchi, Tristan Briant, P. Rapagnani, M. Mohan, N. Man, S. Hebri, Nelson Christensen, A Remilleux, E. Tournefier, F. Cavalier, Matthew Evans, Stefano Bigotta, Ketevan Qipiani, C. Magazzù, Silvio Pardi, O. Torre, O. Rabaste, Leopoldo Milano, C. Tremola, M. Bitossi, A. Di Lieto, A. Reboux, E. Cuoco, S. Rapisarda, T. Pradier, D. Rosińska, M. Vasúth, Salvatore Solimeno, D. Enard, Elena Cesarini, B. Lopez, J. F. Hayau, E. Coccia, F. Robinet, G. Calamai, C. N. Colacino, Joseph M. Kovalik, V. Brisson, G. Matone, C. Van Den Broeck, B. Perniola, M. Was, Ruggero Stanga, S Tissot, Maria Grazia Bernardini, Ph Heusse, D. Buskulic, Zhenyu Zhang, C. Greverie, Rosa Poggiani, R. Chiche, H. Vocca, S. Karkar, A. Gennai, P. Mugnier, Simona Mosca, M. Vavoulidis, S. Vilalte, S. Van Der Putten, Tomasz Bulik, L. Fournier, Th. S. Bauer, François Bondu, G. Giordano, M. Colombini, Francesco Cottone, F. Bellachia, G. Vajente, D. Forest, A. Belletoile, W. Del Pozzo, P. F. Cohadon, H. Heitmann, D. S. Rabeling, Rocco Romano, M. Dialinas, F. Menzinger, Iolanda Ricciardi, F. Carbognani, M. Di Paolo Emilio, A. Bozzi, D. Huet, H Fang, R. Bonnand, E Pacaud, F. Martelli, S Mitra, Laboratoire d'Annecy de Physique des Particules ( LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Savoie Mont Blanc ( USMB [Université de Savoie] [Université de Chambéry] ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de l'Accélérateur Linéaire ( LAL ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), APC - Cosmologie, Physique Corpusculaire et Cosmologie - Collège de France ( PCC ), Collège de France ( CdF ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ) -Collège de France ( CdF ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ) -AstroParticule et Cosmologie ( APC - UMR 7164 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ) -Observatoire de Paris-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Institut de Physique de Rennes ( IPR ), Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire des matériaux avancés ( LMA ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), AstroParticule et Cosmologie ( APC - UMR 7164 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), APC - Gravitation ( APC-Gravitation ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Max-Planck-Institut für Gravitationsphysik (Albert-Einstein-Institut), Max-Planck-Institut-Max-Planck-Institut, T., Accadia, F., Acernese, M., Alshourbagy, P., Amico, F., Antonucci, S., Aoudia, N., Arnaud, C., Arnault, K. G., Arun, P., Astone, S., Avino, D., Babusci, G., Ballardin, F., Barone, G., Barrand, L., Barsotti, M., Barsuglia, A., Basti, Th S., Bauer, F., Beauville, M., Bebronne, M., Bejger, M. G., Beker, F., Bellachia, A., Belletoile, J. L., Beney, M., Bernardini, S., Bigotta, R., Bilhaut, S., Birindelli, M., Bitossi, M. A., Bizouard, M., Blom, C., Boccara, D., Boget, F., Bondu, L., Bonelli, R., Bonnand, V., Boschi, L., Bosi, T., Bouedo, B., Bouhou, A., Bozzi, L., Bracci, S., Braccini, C., Bradaschia, M., Branchesi, T., Briant, A., Brillet, V., Brisson, L., Brocco, T., Bulik, H. J., Bulten, D., Buskulic, C., Buy, G., Cagnoli, G., Calamai, Calloni, Enrico, E., Campagna, B., Canuel, F., Carbognani, L., Carbone, F., Cavalier, R., Cavalieri, R., Cecchi, G., Cella, E., Cesarini, E., Chassande Mottin, S., Chatterji, R., Chiche, A., Chincarini, A., Chiummo, N., Christensen, A. C., Clapson, F., Cleva, E., Coccia, P. F., Cohadon, C. N., Colacino, J., Cola, A., Colla, M., Colombini, G., Conforto, A., Corsi, S., Cortese, F., Cottone, J. P., Coulon, E., Cuoco, S., D'Antonio, G., Daguin, A., Dari, V., Dattilo, P. Y., David, M., Davier, R., Day, G., Debreczeni, G., De Caroli, M., Dehamme, R., Del Fabbro, W., Del Pozzo, M., del Prete, L., Derome, DE ROSA, Rosario, R., Desalvo, M., Dialina, L., Di Fiore, A., Di Lieto, M., Di Paolo Emilio, A., Di Virgilio, A., Dietz, M., Doet, P., Dominici, A., Dominjon, M., Drago, C., Drezen, B., Dujardin, B., Dulach, C., Eder, A., Eleuteri, D., Enard, M., Evan, L., Fabbroni, V., Fafone, H., Fang, I., Ferrante, F., Fidecaro, I., Fiori, R., Flaminio, D., Forest, Forte, LUCA ANTONIO, J. D., Fournier, L., Fournier, J., Franc, O., Francoi, S., Frasca, F., Frasconi, A., Freise, A., Gaddi, M., Galimberti, L., Gammaitoni, P., Ganau, C., Garnier, Garufi, Fabio, M. E., Gáspár, G., Gemme, E., Genin, A., Gennai, G., Gennaro, L., Giacobone, A., Giazotto, G., Giordano, L., Giordano, C., Girard, R., Gouaty, A., Grado, M., Granata, V., Granata, X., Grave, C., Greverie, H., Groenstege, G. M., Guidi, S., Hamdani, J. F., Hayau, S., Hebri, A., Heidmann, H., Heitmann, P., Hello, G., Hemming, E., Henne, R., Hermel, P., Heusse, L., Holloway, D., Huet, M., Iannarelli, P., Jaranowski, D., Jehanno, L., Journet, S., Karkar, T., Ketel, H., Voet, J., Kovalik, I., Kowalska, S., Kreckelbergh, A., Krolak, J. C., Lacotte, B., Lagrange, P., La Penna, M., Laval, J. C., Le Marec, N., Leroy, N., Letendre, T. G. F., Li, B., Lieunard, N., Liguori, O., Lodygensky, B., Lopez, M., Lorenzini, V., Loriette, G., Losurdo, M., Loupia, J. M., Mackowski, T., Maiani, E., Majorana, C., Magazzù, I., Maksimovic, V., Malvezzi, N., Man, S., Mancini, B., Mansoux, M., Mantovani, F., Marchesoni, F., Marion, P., Marin, J., Marque, F., Martelli, A., Masserot, L., Massonnet, G., Matone, L., Matone, M., Mazzoni, F., Menzinger, C., Michel, Milano, Leopoldo, Y., Minenkov, S., Mitra, M., Mohan, J. L., Montorio, R., Morand, F., Moreau, J., Moreau, N., Morgado, A., Morgia, S., Mosca, V., Moscatelli, B., Mour, P., Mugnier, F. A., Mul, L., Naticchioni, I., Neri, F., Nocera, E., Pacaud, G., Pagliaroli, A., Pai, L., Palladino, C., Palomba, F., Paoletti, R., Paoletti, A., Paoli, S., Pardi, G., Parguez, M., Parisi, A., Pasqualetti, R., Passaquieti, D., Passuello, M., Perciballi, B., Perniola, G., Persichetti, S., Petit, M., Pichot, F., Piergiovanni, M., Pietka, R., Pignard, L., Pinard, R., Poggiani, P., Popolizio, T., Pradier, M., Prato, G. A., Prodi, M., Punturo, P., Puppo, K., Qipiani, O., Rabaste, D. S., Rabeling, I., Rácz, F., Raffaelli, P., Rapagnani, S., Rapisarda, V., Re, A., Reboux, T., Regimbau, V., Reita, A., Remilleux, F., Ricci, I., Ricciardi, F., Richard, M., Ripepe, F., Robinet, A., Rocchi, L., Rolland, R., Romano, D., Rosińska, P., Roudier, P., Ruggi, Russo, Guido, L., Salconi, V., Sannibale, B., Sassola, D., Sentenac, S., Solimeno, R., Sottile, L., Sperandio, R., Stanga, R., Sturani, B., Swinkel, M., Tacca, R., Taddei, L., Taffarello, M., Tarallo, S., Tissot, A., Toncelli, M., Tonelli, O., Torre, E., Tournefier, F., Travasso, C., Tremola, E., Turri, G., Vajente, J. F. J., van den Brand, C., Van Den Broeck, S., van der Putten, M., Vasuth, M., Vavoulidi, G., Vedovato, D., Verkindt, F., Vetrano, O., Véziant, A., Viceré, J. Y., Vinet, S., Vilalte, S., Vitale, H., Vocca, R. L., Ward, M., Wa, K., Yamamoto, M., Yvert, J. P., Zendri, Z., Zhang, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut de Physique de Rennes (IPR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des matériaux avancés (LMA), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), (Astro)-Particles Physics, Mathematical Analysis, Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), Physique Corpusculaire et Cosmologie - Collège de France (PCC), Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), APC - Gravitation (APC-Gravitation), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), and Max-Planck-Gesellschaft-Max-Planck-Gesellschaft
- Subjects
Gravitational-wave observatory ,PROTOTYPE ,01 natural sciences ,SCATTERED-LIGHT NOISE ,law.invention ,Detection of gravitational wave ,interferometers ,law ,Instrumentation ,gravitational wave ,Mathematical Physics ,ComputingMilieux_MISCELLANEOUS ,Physics ,SEISMIC NOISE ,Detector ,SUPER ATTENUATOR ,Settore FIS/01 - Fisica Sperimentale ,[ SDU.ASTR.IM ] Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,Interferometry ,[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,[PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,1ST ,SUSPENSION ,Gravitational waves ,[ PHYS.GRQC ] Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,Optics ,Suspensions ,Settore FIS/05 - Astronomia e Astrofisica ,0103 physical sciences ,Detection theory ,Gravitational Waves ,Interferometric Detector ,Electronics ,010306 general physics ,010308 nuclear & particles physics ,business.industry ,Gravitational wave ,Lasers ,Michelson interferometer ,PERFORMANCE ,Antennas ,[SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,[ PHYS.ASTR.IM ] Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,business ,[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph] ,Sensitivity (electronics) ,SHOT-NOISE ,SYSTEM ,PENDULUM - Abstract
This paper presents a complete description of Virgo, the French-Italian gravitational wave detector. The detector, built at Cascina, near Pisa (Italy), is a very large Michelson interferometer, with 3 km-long arms. In this paper, following a presentation of the physics requirements, leading to the specifications for the construction of the detector, a detailed description of all its different elements is given. These include civil engineering infrastructures, a huge ultra-high vacuum (UHV) chamber (about 6000 cubic metres), all of the optical components, including high quality mirrors and their seismic isolating suspensions, all of the electronics required to control the interferometer and for signal detection. The expected performances of these different elements are given, leading to an overall sensitivity curve as a function of the incoming gravitational wave frequency. This description represents the detector as built and used in the first data-taking runs. Improvements in different parts have been and continue to be performed, leading to better sensitivities. These will be detailed in a forthcoming paper. © 2012 IOP Publishing Ltd and Sissa Medialab srl.
- Published
- 2012
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4. Advanced Virgo: a second-generation interferometric gravitational wave detector
- Author
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F Acernese, M Agathos, K Agatsuma, D Aisa, N Allemandou, A Allocca, J Amarni, P Astone, G Balestri, G Ballardin, F Barone, J-P Baronick, M Barsuglia, A Basti, F Basti, Th S Bauer, V Bavigadda, M Bejger, M G Beker, C Belczynski, D Bersanetti, A Bertolini, M Bitossi, M A Bizouard, S Bloemen, M Blom, M Boer, G Bogaert, D Bondi, F Bondu, L Bonelli, R Bonnand, V Boschi, L Bosi, T Bouedo, C Bradaschia, M Branchesi, T Briant, A Brillet, V Brisson, T Bulik, H J Bulten, D Buskulic, C Buy, G Cagnoli, E Calloni, C Campeggi, B Canuel, F Carbognani, F Cavalier, R Cavalieri, G Cella, E Cesarini, E Chassande- Mottin, A Chincarini, A Chiummo, S Chua, F Cleva, E Coccia, P-F Cohadon, A Colla, M Colombini, A Conte, J-P Coulon, E Cuoco, A Dalmaz, S D’Antonio, V Dattilo, M Davier, R Day, G Debreczeni, J Degallaix, S Deléglise, W Del Pozzo, H Dereli, R De Rosa, L Di Fiore, A Di Lieto, A Di Virgilio, M Doets, V Dolique, M Drago, M Ducrot, G Endrőczi, V Fafone, S Farinon, I Ferrante, F Ferrini, F Fidecaro, I Fiori, R Flaminio, J-D Fournier, S Franco, S Frasca, F Frasconi, L Gammaitoni, F Garufi, M Gaspard, A Gatto, G Gemme, B Gendre, E Genin, A Gennai, S Ghosh, L Giacobone, A Giazotto, R Gouaty, M Granata, G Greco, P Groot, G M Guidi, J Harms, A Heidmann, H Heitmann, P Hello, G Hemming, E Hennes, D Hofman, P Jaranowski, R J G Jonker, M Kasprzack, F Kéfélian, I Kowalska, M Kraan, A Królak, A Kutynia, C Lazzaro, M Leonardi, N Leroy, N Letendre, T G F Li, B Lieunard, M Lorenzini, V Loriette, G Losurdo, C Magazzù, E Majorana, I Maksimovic, V Malvezzi, N Man, V Mangano, M Mantovani, F Marchesoni, F Marion, J Marque, F Martelli, L Martellini, A Masserot, D Meacher, J Meidam, F Mezzani, C Michel, L Milano, Y Minenkov, A Moggi, M Mohan, M Montani, N Morgado, B Mours, F Mul, M F Nagy, I Nardecchia, L Naticchioni, G Nelemans, I Neri, M Neri, F Nocera, E Pacaud, C Palomba, F Paoletti, A Paoli, A Pasqualetti, R Passaquieti, D Passuello, M Perciballi, S Petit, M Pichot, F Piergiovanni, G Pillant, A Piluso, L Pinard, R Poggiani, M Prijatelj, G A Prodi, M Punturo, P Puppo, D S Rabeling, I Rácz, P Rapagnani, M Razzano, V Re, T Regimbau, F Ricci, F Robinet, A Rocchi, L Rolland, R Romano, D Rosińska, P Ruggi, E Saracco, B Sassolas, F Schimmel, D Sentenac, V Sequino, S Shah, K Siellez, N Straniero, B Swinkels, M Tacca, M Tonelli, F Travasso, M Turconi, G Vajente, N van Bakel, M van Beuzekom, J F J van den Brand, C Van Den Broeck, M V van der Sluys, J van Heijningen, M Vasúth, G Vedovato, J Veitch, D Verkindt, F Vetrano, A Viceré, J-Y Vinet, G Visser, H Vocca, R Ward, M Was, L-W Wei, M Yvert, A Zadro żny, J-P Zendri, (Astro)-Particles Physics, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Istituto Nazionale di Fisica Nucleare [Sezione di Roma 1] (INFN), Istituto Nazionale di Fisica Nucleare, Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux (ARTEMIS), Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut de Physique de Rennes (IPR), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des matériaux avancés (LMA), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Observatoire de la Côte d'Azur (OCA), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL), VIRGO, Acernese, F., Agathos, M., Agatsuma, K., Aisa, D., Allemandou, N., Allocca, A., Amarni, J., Astone, P., Balestri, G., Ballardin, G., Barone, F., Baronick, J. P., Barsuglia, M., Basti, A., Basti, F., Bauer, T. S., Bavigadda, V., Bejger, M., Beker, M. G., Belczynski, C., Bersanetti, D., Bertolini, A., Bitossi, M., Bizouard, M. A., Bloemen, S., Blom, M., Boer, M., Bogaert, G., Bondi, D., Bondu, F., Bonelli, L., Bonnand, R., Boschi, V., Bosi, L., Bouedo, T., Bradaschia, C., Branchesi, M., Briant, T., Brillet, A., Brisson, V., Bulik, T., Bulten, H. J., Buskulic, D., Buy, C., Cagnoli, G., Calloni, Enrico, Campeggi, C., Canuel, B., Carbognani, F., Cavalier, F., Cavalieri, R., Cella, G., Cesarini, E., Chassande Mottin, E., Chincarini, A., Chiummo, A., Chua, S., Cleva, F., Coccia, E., Cohadon, P. F., Colla, A., Colombini, M., Conte, A., Coulon, J. P., Cuoco, E., Dalmaz, A., D'Antonio, S., Dattilo, V., Davier, M., Day, R., Debreczeni, G., Degallaix, J., Deleglise, S., Pozzo, W. D., Dereli, H., DE ROSA, Rosario, Fiore, L. D., Lieto, A. D., Virgilio, A. D., Doets, M., Dolique, V., Drago, M., Ducrot, M., Endroczi, G., Fafone, V., Farinon, S., Ferrante, I., Ferrini, F., Fidecaro, F., Fiori, I., Flaminio, R., Fournier, J. D., Franco, S., Frasca, S., Frasconi, F., Gammaitoni, L., Garufi, Fabio, Gaspard, M., Gatto, A., Gemme, G., Gendre, B., Genin, E., Gennai, A., Ghosh, S., Giacobone, L., Giazotto, A., Gouaty, R., Granata, M., Greco, G., Groot, P., Guidi, G. M., Harms, J., Heidmann, A., Heitmann, H., Hello, P., Hemming, G., Hennes, E., Hofman, D., Jaranowski, P., R. J. G., Kasprzack, M., Kefelian, F., Kowalska, I., Kraan, M., Krolak, A., Kutynia, A., Lazzaro, C., Leonardi, M., Leroy, N., Letendre, N., T. G. F., Lieunard, B., Lorenzini, M., Loriette, V., Losurdo, G., Magazzu, C., Majorana, E., Maksimovic, I., Malvezzi, V., Man, N., Mangano, V., Mantovani, M., Marchesoni, F., Marion, F., Marque, J., Martelli, F., Martellini, L., Masserot, A., Meacher, D., Meidam, J., Mezzani, F., Michel, C., Milano, Leopoldo, Minenkov, Y., Moggi, A., Mohan, M., Montani, M., Morgado, N., Mours, B., Mul, F., Nagy, M. F., Nardecchia, I., Naticchioni, L., Nelemans, G., Neri, I., Neri, M., Nocera, F., Pacaud, E., Palomba, C., Paoletti, F., Paoli, A., Pasqualetti, A., Passaquieti, R., Passuello, D., Perciballi, M., Petit, S., Pichot, M., Piergiovanni, F., Pillant, G., Piluso, A., Pinard, L., Poggiani, R., Prijatelj, M., Prodi, G. A., Punturo, M., Puppo, P., Rabeling, D. S., Racz, I., Rapagnani, P., Razzano, M., Re, V., Regimbau, T., Ricci, F., Robinet, F., Rocchi, A., Rolland, L., Romano, R., Rosinska, D., Ruggi, P., Saracco, E., Sassolas, B., Schimmel, F., Sentenac, D., Sequino, V., Shah, S., Siellez, K., Straniero, N., Swinkels, B., Tacca, M., Tonelli, M., Travasso, F., Turconi, M., Vajente, G., Bakel, N. v., Beuzekom, M. v., J. F. J., Den, C. v., Van, M. V., Heijningen, J. v., Vasuth, M., Vedovato, G., Veitch, J., Verkindt, D., Vetrano, F., Vicere, A., Vinet, J. Y., Visser, G., Vocca, H., Ward, R., Was, M., Wei, L. W., Yvert, M., Zadrozny, A., Zendri, J. P., Laboratoire d'Annecy de Physique des Particules ( LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Savoie Mont Blanc ( USMB [Université de Savoie] [Université de Chambéry] ) -Centre National de la Recherche Scientifique ( CNRS ), AstroParticule et Cosmologie ( APC - UMR 7164 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), APC - Cosmologie, Physique Corpusculaire et Cosmologie - Collège de France ( PCC ), Collège de France ( CdF ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ) -Collège de France ( CdF ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ) -AstroParticule et Cosmologie ( APC - UMR 7164 ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ) -Observatoire de Paris-Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ), Department of Physics, Università degli Studi di Roma 'La Sapienza' [Rome], Laboratoire de l'Accélérateur Linéaire ( LAL ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux ( ARTEMIS ), Université Nice Sophia Antipolis ( UNS ), Université Côte d'Azur ( UCA ) -Université Côte d'Azur ( UCA ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire de la Côte d'Azur, Université Côte d'Azur ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de Physique de Rennes ( IPR ), Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire des matériaux avancés ( LMA ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), APC - Gravitation ( APC-Gravitation ), Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Centre National de la Recherche Scientifique ( CNRS ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Max-Planck-Institut für Gravitationsphysik (Albert-Einstein-Institut), Max-Planck-Institut-Max-Planck-Institut, Observatoire de la Côte d'Azur ( OCA ), Centre National de la Recherche Scientifique ( CNRS ), ESPCI ParisTech, Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)
- Subjects
Physics and Astronomy (miscellaneous) ,Astronomy ,FARADAY ISOLATORS ,gravitational wave detectors ,gravitational waves ,laser interferometry ,Astrophysics::Cosmology and Extragalactic Astrophysics ,ravitational wave detectors ,01 natural sciences ,SUSPENSION ,[ PHYS.GRQC ] Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,Gravitational waves ,Gravitational wave detectors ,General Relativity and Quantum Cosmology ,ACCELEROMETER ,0103 physical sciences ,GW151226 ,Interferometric gravitational wave detector ,KAGRA ,[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,[ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det] ,010303 astronomy & astrophysics ,Physics ,Gravitational wave detectors, Laser interferometry, Gravitational waves ,010308 nuclear & particles physics ,Gravitational wave ,Settore FIS/01 - Fisica Sperimentale ,Detector ,Astrophysics::Instrumentation and Methods for Astrophysics ,SENSOR ,THERMAL NOISE ,FUSED-SILICA ,Galaxy ,LIGO ,COMPENSATION ,Upgrade ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,MODES ,[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,RADIATION ,ravitational wave detectors, laser interferometry, gravitational waves ,Laser interferometry ,SYSTEM ,PENDULUM - Abstract
Advanced Virgo is the project to upgrade the Virgo interferometric detector of gravitational waves, with the aim of increasing the number of observable galaxies (and thus the detection rate) by three orders of magnitude. The project is now in an advanced construction phase and the assembly and integration will be completed by the end of 2015. Advanced Virgo will be part of a network, alongside the two Advanced LIGO detectors in the US and GEO HF in Germany, with the goal of contributing to the early detection of gravitational waves and to opening a new window of observation on the universe. In this paper we describe the main features of the Advanced Virgo detector and outline the status of the construction. journal_title: Classical and Quantum Gravity article_type: paper article_title: Advanced Virgo: a second-generation interferometric gravitational wave detector copyright_information: © 2015 IOP Publishing Ltd date_received: 2014-08-18 date_accepted: 2014-10-20 date_epub: 2014-12-18 ispartof: Classical and Quantum Gravity vol:32 issue:2 status: published
- Published
- 2015
- Full Text
- View/download PDF
5. ChemInform Abstract: Preparation and anti-HIV Activity of N-3-Substituted Thymidine Nucleoside Analogues
- Author
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C. Ferrieux, C. Rombi, J.‐C. Florent, M. Lemaitre, D. Thierry, F. Begassat, E. Pacaud, A. Bugnicourt, M. Maillard, Claude Monneret, A. Zerial, and David S. Grierson
- Subjects
Anti hiv activity ,chemistry.chemical_compound ,Biochemistry ,Chemistry ,Stereochemistry ,Nucleic acid ,General Medicine ,Thymidine ,Nucleoside - Published
- 2010
- Full Text
- View/download PDF
6. Large mirror surface control by corrective coating
- Author
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L. Pinard, Frédérique Marion, B. Lagrange, R. Flaminio, Pierre Mugnier, Laurent Giacobone, E. Pacaud, B. Mours, Christophe Michel, Romain Bonnand, Jerome Degallaix, Laboratoire des matériaux avancés (LMA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), and VIRGO
- Subjects
Physics ,[PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,Gravitational-wave observatory ,Physics and Astronomy (miscellaneous) ,010308 nuclear & particles physics ,business.industry ,Flatness (systems theory) ,Polishing ,engineering.material ,01 natural sciences ,LIGO ,[SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM] ,Surface coating ,Interferometry ,Optics ,Coating ,0103 physical sciences ,[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc] ,engineering ,Astronomical interferometer ,business ,010303 astronomy & astrophysics - Abstract
The Advanced Virgo gravitational wave detector aims at a sensitivity ten times better than the initial LIGO and Virgo detectors. This implies very stringent requirement on the optical losses in the interferometer arm cavities. In this paper we focus on the mirrors which form the interferometer arm cavities and that require a surface figure error to be well below one nanometre on a diameter of 150 mm. This 'sub-nanometric flatness' is not achievable by classical polishing on such a large diameter. Therefore we present the corrective coating technique which has been developed to reach this requirement. Its principle is to add a non-uniform thin film on top of the substrate in order to flatten its surface. In this paper we will introduce the Advanced Virgo requirements and present the basic principle of the corrective coating technique. Then we show the results obtained experimentally on an initial Virgo substrate. Finally we provide an evaluation of the round-trip losses in the Fabry-Perot arm cavities once the corrected surface is used.
- Published
- 2013
- Full Text
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7. Determination of 125I-labelled thyroxine glucuronide by reversed-phase high-performance liquid chromatography using on-line radiochemical detection to determine UDPglucuronosyltransferase activity
- Author
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V. de Sandro, E. Pacaud, Gérard Ducrotoy, D. Lurier, and Lysiane Richert
- Subjects
Detection limit ,Male ,Chromatography ,Radiochemistry ,Chemistry ,Glucuronidation ,Substrate (chemistry) ,Glucuronates ,Rats, Inbred Strains ,General Chemistry ,Thyroxine glucuronide ,High-performance liquid chromatography ,Highly sensitive ,Rats ,Iodine Radioisotopes ,Kinetics ,Thyroxine ,Microsome ,Microsomes, Liver ,Animals ,Hepatic microsome ,Glucuronosyltransferase ,Chromatography, High Pressure Liquid - Abstract
A convenient, fast and highly sensitive high-performance liquid chromatographic method, using on-line radiochemical detection, is described for the determination of [125I]thyroxine glucuronide. The method involves direct injection of the supernatant, a total analysis time of 30 min and a detection limit of 1 pmol. The results demonstrate that the method is suitable for the determination of UDPglucuronosyltransferase activity with thyroxine as substrate in native hepatic microsomes. The rate of thyroxine glucuronidation in microsomes from rats treated with Arodor 1254 was ten times higher than in control microsomes, indicating that with this method, increases of UDPglucuronosyltransferase thyroxine activities, often associated with hepatic induction process involved in thyroid hypertrophy, can be easily detected. This method could also be applied to all experimental biological systems that involve the separation and quantification of [125I]thyroxine and [125I]thyroxine glucuronide.
- Published
- 1991
8. Upper-limit on the Advanced Virgo output mode cleaner cavity length noise.
- Author
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R Bonnand, M Ducrot, R Gouaty, F Marion, A Masserot, B Mours, E Pacaud, L Rolland, and M Was
- Subjects
GRAVITATIONAL wave detectors ,OPTICAL resonators ,RADIO frequency ,PIEZOELECTRIC actuators ,THERMOELECTRIC cooling - Abstract
The Advanced Virgo detector uses two monolithic optical cavities at its output port to suppress higher order modes and radio frequency sidebands from the carrier light used for gravitational wave detection. These two cavities in series form the output mode cleaner. We present a measured upper limit on the length noise of these cavities that is consistent with the thermo-refractive noise prediction of at 15 Hz. The cavity length is controlled using Peltier cells and piezo-electric actuators to maintain resonance on the incoming light. A length lock precision of m is achieved. These two results are combined to demonstrate that the broadband length noise of the output mode cleaner in the 10–60 Hz band is at least a factor 10 below other expected noise sources in the Advanced Virgo detector design configuration. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
9. On the relationship between molecular mass and anticoagulant activity in a low molecular weight heparin (enoxaparin).
- Author
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Bendetowicz AV, Pacaud E, Béguin S, Uzan A, and Hemker HC
- Subjects
- Antithrombin III chemistry, Fluorescence, Heparin, Low-Molecular-Weight chemistry, Humans, Molecular Weight, Thrombin biosynthesis, Heparin, Low-Molecular-Weight pharmacology, Thrombin antagonists & inhibitors, Thromboplastin antagonists & inhibitors
- Abstract
A low molecular weight heparin (enoxaparin, mean molecular weight approximately 4,400) was separated by gel chromatography into eight different fractions with a narrow distribution around the following mean molecular weights: 1,800, 2,400, 2,900, 4,200, 6,200, 8,600, 9,800 and 11,000. We compared the influence of enoxaparin on the generation of thrombin in plasma to that of the eight fractions. We determined: a) the % of material with high affinity to antithrombin III (HAM) and the % of HAM above the critical chain length necessary to allow for thrombin inhibition (ACLM), b) the specific catalytic activity on the decay of endogenous thrombin, and c) the inhibition of over-all thrombin formation in the extrinsic and the intrinsic pathway. From b and c we calculated the inhibition of prothrombin conversion in these pathways. We found that a) there is a gradual decrease of the HAM fraction with decreasing molecular weight; b) the specific catalytic activity for the inactivation of thrombin does not vary significantly between the fractions when expressed in terms of ACLM; c) the potency to inhibit prothrombin conversion does not vary significantly between the fractions when expressed in terms of HAM.
- Published
- 1992
10. Determination of 125I-labelled thyroxine glucuronide by reversed-phase high-performance liquid chromatography using on-line radiochemical detection to determine UDPglucuronosyltransferase activity.
- Author
-
Ducrotoy G, Richert L, De Sandro V, Lurier D, and Pacaud E
- Subjects
- Animals, Chromatography, High Pressure Liquid methods, Iodine Radioisotopes, Kinetics, Male, Radiochemistry, Rats, Rats, Inbred Strains, Thyroxine metabolism, Glucuronates metabolism, Glucuronosyltransferase metabolism, Microsomes, Liver enzymology, Thyroxine analogs & derivatives
- Abstract
A convenient, fast and highly sensitive high-performance liquid chromatographic method, using on-line radiochemical detection, is described for the determination of [125I]thyroxine glucuronide. The method involves direct injection of the supernatant, a total analysis time of 30 min and a detection limit of 1 pmol. The results demonstrate that the method is suitable for the determination of UDPglucuronosyltransferase activity with thyroxine as substrate in native hepatic microsomes. The rate of thyroxine glucuronidation in microsomes from rats treated with Arodor 1254 was ten times higher than in control microsomes, indicating that with this method, increases of UDPglucuronosyltransferase thyroxine activities, often associated with hepatic induction process involved in thyroid hypertrophy, can be easily detected. This method could also be applied to all experimental biological systems that involve the separation and quantification of [125I]thyroxine and [125I]thyroxine glucuronide.
- Published
- 1991
- Full Text
- View/download PDF
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