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2. New solar axion search using the CERN Axion Solar Telescope withHe4filling

Author

M. Arik, S. Aune, K. Barth, A. Belov, H. Bräuninger, J. Bremer, V. Burwitz, G. Cantatore, J. M. Carmona, S. A. Cetin, J. I. Collar, E. Da Riva, T. Dafni, M. Davenport, A. Dermenev, C. Eleftheriadis, N. Elias, G. Fanourakis, E. Ferrer-Ribas, J. Galán, J. A. García, A. Gardikiotis, J. G. Garza, E. N. Gazis, T. Geralis, E. Georgiopoulou, I. Giomataris, S. Gninenko, M. Gómez Marzoa, M. D. Hasinoff, D. H. H. Hoffmann, F. J. Iguaz, I. G. Irastorza, J. Jacoby, K. Jakovčić, M. Karuza, M. Kavuk, M. Krčmar, M. Kuster, B. Lakić, J. M. Laurent, A. Liolios, A. Ljubičić, G. Luzón, S. Neff, T. Niinikoski, A. Nordt, I. Ortega, T. Papaevangelou, M. J. Pivovaroff, G. Raffelt, A. Rodríguez, M. Rosu, J. Ruz, I. Savvidis, I. Shilon, S. K. Solanki, L. Stewart, A. Tomás, T. Vafeiadis, J. Villar, J. K. Vogel, S. C. Yildiz, and K. Zioutas

Published
2015
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3. Search for Solar Axions by the CERN Axion Solar Telescope withHe3Buffer Gas: Closing the Hot Dark Matter Gap

Author

M. Arik, S. Aune, K. Barth, A. Belov, S. Borghi, H. Bräuninger, G. Cantatore, J. M. Carmona, S. A. Cetin, J. I. Collar, E. Da Riva, T. Dafni, M. Davenport, C. Eleftheriadis, N. Elias, G. Fanourakis, E. Ferrer-Ribas, P. Friedrich, J. Galán, J. A. García, A. Gardikiotis, J. G. Garza, E. N. Gazis, T. Geralis, E. Georgiopoulou, I. Giomataris, S. Gninenko, H. Gómez, M. Gómez Marzoa, E. Gruber, T. Guthörl, R. Hartmann, S. Hauf, F. Haug, M. D. Hasinoff, D. H. H. Hoffmann, F. J. Iguaz, I. G. Irastorza, J. Jacoby, K. Jakovčić, M. Karuza, K. Königsmann, R. Kotthaus, M. Krčmar, M. Kuster, B. Lakić, P. M. Lang, J. M. Laurent, A. Liolios, A. Ljubičić, G. Luzón, S. Neff, T. Niinikoski, A. Nordt, T. Papaevangelou, M. J. Pivovaroff, G. Raffelt, H. Riege, A. Rodríguez, M. Rosu, J. Ruz, I. Savvidis, I. Shilon, P. S. Silva, S. K. Solanki, L. Stewart, A. Tomás, M. Tsagri, K. van Bibber, T. Vafeiadis, J. Villar, J. K. Vogel, S. C. Yildiz, and K. Zioutas

Published
2014
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4. An update on the Axion Helioscopes front: current activities at CAST and the IAXO project

Author

Joachim Jacoby, J. I. Collar, H. Ten Kate, Fritz Caspers, Julia Vogel, J. Kaminski, H. Silva, Giovanni Cantatore, Benito Gimeno, S. C. Yildiz, M. Betz, Alexey Dudarev, Georg G. Raffelt, A. Belov, F.J. Iguaz, Rainer Kotthaus, Javier Redondo, F. Haug, K. Barth, G. Luzón, Klaus Kurt Desch, C. Eleftheriadis, S. Caspi, P. Brax, Georgios Fanourakis, W. C. Wester, Hector Gomez, J. M. Laurent, N. Breijnholt, I. Dratchnev, Toyokazu Sekiguchi, S. Neff, L. Stewart, Joerg Jaeckel, Amanda Weltman, Marin Karuza, C. Krieger, Pierre Sikivie, A. Tomás, S. Aune, C. Nones, Heinrich Bräuninger, Serkant Ali Cetin, M. Rosu, I. G. Irastorza, J. M. Carmona, Babette Döbrich, Krešimir Jakovčić, Steffen Hauf, Takashi Hiramatsu, Biljana Lakić, Milica Krčmar, Evangelos Gazis, M. Davenport, Dieter H. H. Hoffmann, T. Papaevangelou, J.A. Villar, A. V. Derbin, Ante Ljubičić, Dieter Horns, S. N. Gninenko, A. Diago, I. Ortega, S. Matsuki, E. Gruber, Sergey Troitsky, T. Dafni, J. G. Garza, I. Savvidis, Andreas Ringwald, A. Lindner, Jordi Isern, M. Arik, Javier Galan, Ken'ichi Saikawa, E. Georgiopoulou, T. Guthörl, Eduardo Guendelman, Adriane De Assis Lawisch Rodriguez, I. Shilon, D. Chelouche, S. Russenschuck, Kenichi Imai, V. N. Muratova, P. Vedrine, F.E. Christensen, T. O. Niinikoski, E. Ferrer-Ribas, F. T. Avignone, Charles J. Hailey, M. D. Hasinoff, Peter Friedrich, M. J. Pivovaroff, Konstantin Zioutas, Sami K. Solanki, Louis Walckiers, H. Riege, Pierre Brun, Konstantinos Kousouris, Markus Kuster, A. Dael, T. Geralis, Gianpaolo Carosi, J. A. Garcia, A. Gardikiotis, Yannis K. Semertzidis, Eric Armengaud, Raimo Hartmann, Theodoros Vafeiadis, J. Ruz, K. Königsmann, Masahiro Kawasaki, D. González-Díaz, I. Giomataris, K. van Bibber, Olivier Limousin, A.C. Jakobsen, A. Liolios, Dafni, T, Arik, M., Armengaud, E., Aune, S., Avignone, F. T., Barth, K., Belov, A., Betz, M., Bräuninger, H., Brax, P., Breijnholt, N., Brun, P., Cantatore, Giovanni, Carmona, J. M., Carosi, G. P., Caspers, F., Caspi, S., Cetin, S. A., Chelouche, D., Christensen, F. E., Collar, J. I., Dael, A., Davenport, M., Derbin, A. V., Desch, K., Diago, A., Döbrich, B., Dratchnev, I., Dudarev, A., Eleftheriadis, C., Fanourakis, G., Ferrer Ribas, E., Friedrich, P., Galán, J., García, J. A., Gardikiotis, A., Garza, J. G., Gazis, E. N., Georgiopoulou, E., Geralis, T., Gimeno, B., Giomataris, I., Gninenko, S., Gómez, H., González Díaz, D., Gruber, E., Guendelman, E., Guthörl, T., Hailey, C. J., Hartmann, R., Hauf, S., Haug, F., Hasinoff, M. D., Hiramatsu, T., Hoffmann, D. H. H., Horns, D., Iguaz, F. J., Irastorza, I. G., Isern, J., Imai, K., Jacoby, J., Jaeckel, J., Jakobsen, A. C., Jakovcić, K., Kaminski, J., Kawasaki, M., Karuza, M., Königsmann, K., Kotthaus, R., Krcmar, M., Kousouris, K., Krieger, C., Kuster, M., Lakić, B., Laurent, J. M., Limousin, O., Lindner, A., Liolios, A., Ljubicić, A., Luzón, G., Matsuki, S., Muratova, V. N., Neff, S., Niinikoski, T., Nones, C., Ortega, I., Papaevangelou, T., Pivovaroff, M. J., Raffelt, G., Redondo, J., Riege, H., Ringwald, A., Rodríguez, A., Rosu, M., Russenschuck, S., Ruz, J., Saikawa, K., Savvidis, I., Sekiguchi, T., Semertzidis, Y. K., Shilon, I., Sikivie, P., Silva, H., Solanki, S. K., Stewart, L., ten Kate, H. H. J., Tomas, A., Troitsky, S., Vafeiadis, T., van Bibber, K., Vedrine, P., Villar, J. A., Vogel, J. K., Walckiers, L., Weltman, A., Wester, W., Yildiz, S. C., Zioutas, K., Doğuş Üniversitesi, Fen Edebiyat Fakültesi, Fizik Bölümü, TR3959, Çetin, Serkant Ali, Arık, Metin, and Yıldız, Süleyman Cenk

Subjects
X-Ray Focusing Devices, X-ray detector, Particle physics, Nuclear and High Energy Physics, X-ray focusing device, Axions, Dark matter, Magnet Development, Micromegas detector, axions, dark matter, x-ray, detectors, micromegas detectors, x-ray focusing devices, magnet development, CAST, IAXO, 01 natural sciences, Axion, Primary (astronomy), Observatory, 0103 physical sciences, Dark Matter, X-Ray Detectors, 010306 general physics, Physics, Helioscope, Micromegas Detectors, 010308 nuclear & particles physics, Magnet development, Micromegas detectors, X-ray detectors, X-ray focusing devices, Orders of magnitude (time), Experimental methods, CERN Axion Solar Telescope
Abstract

Çetin, Serkant Ali (Dogus Author) -- Arık, Metin (Dogus Author) -- Yıldız, Süleyman Cenk (Dogus Author) Although they have not yet been detected, axions and axion-like particles (ALPs) continue to maintain the interest (even increasingly so) of the rare-event searches community as viable candidates for the Dark Matter of the Universe but also as a solution for several other puzzles of astrophysics. Their property of coupling to photons has inspired different experimental methods for their detection, one of which is the helioscope technique. The CERN Axion Solar Telescope (CAST) is the most sensitive helioscope built up to date and has recently published part of the latest data taken with the magnet bores gradually filled with He-3, probing the mass range up to 1.17 eV. The International AXion Observatory (IAXO) is being proposed as a facility where different axion studies can be performed, with the primary goal to study axions coming from the Sun. Designed to maximize sensitivity, it will improve the levels reached by CAST by almost 5 orders of magnitude in signal detection, that is more than one order of magnitude in terms of gay. Here we will summarize the most important aspects of the helioscopes, and focus mainly on IAXO, based on the recent papers [1, 2].

Published
2016
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5. The mysterious Sun: a source and a trap of exotica

Author

Konstantin Zioutas, Yannis K. Semertzidis, T. Dafni, T. Papaevangelou, M. Tsagri, Vassilis Anastassopoulos, and E. Georgiopoulou

Subjects
Trap (computing), Physics, History, Solar phenomena, Solar flare, Physics::Space Physics, Astrophysics::Solar and Stellar Astrophysics, Astronomy, Astrophysics::Earth and Planetary Astrophysics, Astrophysics, Computer Science Applications, Education
Abstract

A few solar phenomena are given whose origin remains rather mysterious. The claimed observations of anomalous nuclear decays suggest new experiments, whose design should be observationally driven, i.e., going beyond conventional thinking. Also, the non-observation of delayed solar radioactivity after few large flares makes this issue more puzzling, while the solar flare trigger is considered anyhow as one of the biggest solar mysteries.

Published
2011
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6. 728 Head Injuries in Childhood

Author

E. Michael, E. Karachanidi, M Papoula, T Syriopoulou, G Nikolaou, E. Fourlani, E Georgiopoulou, and E Kostopoulou

Subjects
Pediatrics, medicine.medical_specialty, business.industry, Head (linguistics), Pediatrics, Perinatology and Child Health, Head injury, Concussion, medicine, Soft tissue, medicine.disease, business
Abstract

Background and aims: We studied during 3 years (2007- 2009) 579 children, 1-14 years old (402 boys, 177 girls) who were administrated to Emergency Room of our Hospital because of head injury. Methods: The study‘; s children were classified according to sex, age (1-4 years old, 5-8 years old, 9-14 years old), trauma’s type, way and place of injury. Results: In 138 children (23.8%) were observed injuries of head's soft tissues, in 228 (39.4%) ruptured injuries, in 81 (14%) small injuries and hacks, in 5 (0.9%) injuries that caused concussion, in 85 (14.6%) traumatic brain injuries. Accidents were more often happened because of falls, at 83.4 % of children (at home at 29.4%, outdoors at 54.5% and at school at 16.1%), while 7.3% of incidents concerned car accidents. Increased injuries' frequency was mainly observed at children 1- 4 years old, at 56.1%, boys in majority. 52 children (9%) were hospitalized for further observation, while 1% was evacuated. Conclusions

Published
2010
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7. Search for Solar Axions by the CERN Axion Solar Telescope with He3 Buffer Gas: Closing the Hot Dark Matter Gap

Author

Arik, M., Aune, S., Barth, K., Belov, A., Borghi, S., Brauninger, H., Cantatore, Giovanni, Carmona, J. M., Cetin, S. A., Da Riva, J. I. Collar E., Dafni, T., Davenport, M., Eleftheriadis, C., Elias, N., Fanourakis, G., Ferrer Ribas, E., Friedrich, P., Galan, J., Garcia, J. A., Gardikiotis, A., Garza, J. G., Gazis, E. N., Geralis, T., Georgiopoulou, E., Giomataris, I., Gninenko, S., Gomez, H., Gomez Marzoa, M., Gruber, E., Guthorl, T., Hartmann, R., Hauf, S., Haug, F., Hasinoff, M. D., Hoffmann, D. H. H., Iguaz, F. J., Irastorza, I. G., Jacoby, J., Jakovcic, K., Karuza, M., Konigsmann, K., Kotthaus, R., Krcmar, M., Kuster, M., Lakic, B., Lang, P. M., Laurent, J. M., Liolios, A., Ljubicic, A., Lozza, V., Luzon, G., Neff, S., Niinikoski, T., Nordt, A., Papaevangelou, T., Pivovaroff, M. J., Raffelt, G., Riege, H., Rodriguez, A., Rosu, M., Ruz, J., Savvidis, I., Shilon, I., Silva, P. S., Solanki, S. K., Stewart, L., Tomas, A., Tsagri, M., van Bibber, K., Vafeiadis, T., Villar, J., Vogel, J. K., Yildiz, S. C., Zioutas, K., M., Arik, S., Aune, K., Barth, A., Belov, S., Borghi, H., Brauninger, Cantatore, Giovanni, J. M., Carmona, S. A., Cetin, J. I. Collar E., Da Riva, T., Dafni, M., Davenport, C., Eleftheriadi, N., Elia, G., Fanouraki, E., Ferrer Riba, P., Friedrich, J., Galan, J. A., Garcia, A., Gardikioti, J. G., Garza, E. N., Gazi, T., Gerali, E., Georgiopoulou, I., Giomatari, S., Gninenko, H., Gomez, M., Gomez Marzoa, E., Gruber, T., Guthorl, R., Hartmann, S., Hauf, F., Haug, M. D., Hasinoff, D. H. H., Hoffmann, F. J., Iguaz, I. G., Irastorza, J., Jacoby, K., Jakovcic, M., Karuza, K., Konigsmann, R., Kotthau, M., Krcmar, M., Kuster, B., Lakic, P. M., Lang, J. M., Laurent, A., Liolio, A., Ljubicic, V., Lozza, G., Luzon, S., Neff, T., Niinikoski, A., Nordt, T., Papaevangelou, M. J., Pivovaroff, G., Raffelt, H., Riege, A., Rodriguez, M., Rosu, J., Ruz, I., Savvidi, I., Shilon, P. S., Silva, S. K., Solanki, L., Stewart, A., Toma, M., Tsagri, K., van Bibber, T., Vafeiadi, J., Villar, J. K., Vogel, S. C., Yildiz, and K., Zioutas

Subjects
solar axions, dark matter, Photon detection, solar axion, Physics::Instrumentation and Detectors, Astrophysics::Solar and Stellar Astrophysics, Astrophysics::Earth and Planetary Astrophysics
Abstract

The CERN Axion Solar Telescope (CAST) has finished its search for solar axions with 3^He buffer gas, covering the search range 0.64 eV < m_a

Published
2014

8. Cyclodextrins as nanocarriers of hydrophobic silicon phthalocyanine dichloride for the enhancement of photodynamic therapy effect.

Author

Georgiopoulou E, Kavetsou E, Alexandratou E, Detsi A, and Politopoulos K

Abstract

In this study, silicon phthalocyanine dichloride (SiCl 2 Pc) was successfully encapsulated in β-cyclodextrin (β-CD) and hydroxy-propyl-β-cyclodextrin (HP-β-CD) using the kneading method. Dynamic Light Scattering (DLS) demonstrated complexes of various hydrodynamic diameters with moderate stability in aqueous solutions. Their structural characterization by Infrared Spectroscopy (FT- IR) indicated that a part of phthalocyanine is located inside the cyclodextrin cavity. Both photophysical and photochemical studies showed that phthalocyanine's encapsulation in cyclodextrins increased its aqueous solubility. The photodynamic studies against A431 cancer cell line indicated that the complexes are more effective than pure SiCl 2 Pc. Pure SiCl 2 Pc's photodynamic effect is characterized as dose-dependent, whereas both complexes presented a biphasic dose-response photodynamic effect. For the highest energy dose of 3.24 J/cm 2 , pure SiCl 2 Pc induced mild cell toxicity. SiCl 2 Pc-β-CD complex was the most promising photosensitizer, exhibiting the highest photodynamic effect when irradiated at 2.16 J/cm 2 ., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Published
2024
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9. Search for solar axions by the CERN axion solar telescope with 3He buffer gas: closing the hot dark matter gap.

Author

Arik M, Aune S, Barth K, Belov A, Borghi S, Bräuninger H, Cantatore G, Carmona JM, Cetin SA, Collar JI, Da Riva E, Dafni T, Davenport M, Eleftheriadis C, Elias N, Fanourakis G, Ferrer-Ribas E, Friedrich P, Galán J, García JA, Gardikiotis A, Garza JG, Gazis EN, Geralis T, Georgiopoulou E, Giomataris I, Gninenko S, Gómez H, Gómez Marzoa M, Gruber E, Guthörl T, Hartmann R, Hauf S, Haug F, Hasinoff MD, Hoffmann DH, Iguaz FJ, Irastorza IG, Jacoby J, Jakovčić K, Karuza M, Königsmann K, Kotthaus R, Krčmar M, Kuster M, Lakić B, Lang PM, Laurent JM, Liolios A, Ljubičić A, Luzón G, Neff S, Niinikoski T, Nordt A, Papaevangelou T, Pivovaroff MJ, Raffelt G, Riege H, Rodríguez A, Rosu M, Ruz J, Savvidis I, Shilon I, Silva PS, Solanki SK, Stewart L, Tomás A, Tsagri M, van Bibber K, Vafeiadis T, Villar J, Vogel JK, Yildiz SC, and Zioutas K

Abstract

The CERN Axion Solar Telescope has finished its search for solar axions with (3)He buffer gas, covering the search range 0.64 eV ≲ ma ≲ 1.17 eV. This closes the gap to the cosmological hot dark matter limit and actually overlaps with it. From the absence of excess x rays when the magnet was pointing to the Sun we set a typical upper limit on the axion-photon coupling of gaγ ≲ 3.3 × 10(-10)  GeV(-1) at 95% C.L., with the exact value depending on the pressure setting. Future direct solar axion searches will focus on increasing the sensitivity to smaller values of gaγ, for example by the currently discussed next generation helioscope International AXion Observatory.

Published
2014
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10. Autonomic effects of nebivolol versus atenolol in healthy subjects.

Author

Chiladakis JA, Georgiopoulou E, and Alexopoulos D

Subjects
Administration, Oral, Adult, Atenolol administration & dosage, Autonomic Nervous System physiology, Benzopyrans administration & dosage, Chronobiology Phenomena, Dose-Response Relationship, Drug, Electrocardiography, Ambulatory, Ethanolamines administration & dosage, Female, Heart Rate drug effects, Heart Rate physiology, Humans, Male, Nebivolol, Prospective Studies, Time Factors, Adrenergic beta-Antagonists pharmacokinetics, Atenolol pharmacokinetics, Autonomic Nervous System drug effects, Benzopyrans pharmacokinetics, Ethanolamines pharmacokinetics
Abstract

Purpose: Nitric oxide may stimulate sympathoinhibitory reflexes. Nebivolol is a beta(1) selective adrenergic receptor antagonist with ancillary vasodilating properties by modulating nitric oxide secretion. We investigated whether nebivolol affects autonomic function differently compared with atenolol, another selective beta(1)-blocker without vasorelaxant actions., Methods: Fourteen healthy volunteers (9 men, 5 women; 25 +/- 3.7 years) received single oral doses of 5 mg nebivolol, 50 mg atenolol, and 100 mg atenolol, each taken for a 2-week period. Heart rate variability (HRV) measurements in time- (SDNN; rMSSD; pNN50) and frequency-domain (low frequency-LF; high frequency-HF; LF/HF ratio) were used to study the autonomic effects of the three regimens on the same patients from serial 24-hour ECGs., Results: Both nebivolol and atenolol, the 50 mg dose as well as the 100 mg dose, produced similar decreases in heart rate compared with baseline throughout the 24-h period (from 82 +/- 9 beats/min to 72 +/- 7 beats/min, 69 +/- 9, and 68 +/- 8 beats/min, respectively, p < 0.001). Overall, the administration of each beta -blocker led to directionally similar increases in the HRV variables, which were most significant following 100 mg atenolol. Nebivolol and the 50 mg dose of atenolol produced similar increases in rMSSD and pNN50 during the entire 24-h period, and in HF power, particularly during the nighttime (p < 0.05). However, the coefficient of HF variance resulted in similar values after either beta -blocker regimen. The LF/HF ratio was most reduced throughout the 24-h period following 100 mg atenolol (p < 0.001), and to a similar extent decreased in the nighttime following nebivolol and atenolol 50 mg (p < 0.01)., Conclusions: Nebivolol 5 mg exerts similar effects on time and frequency domain indexes of HRV as 50 mg atenolol. Nebivolol attenuates sympathetic tone, but does not appear to promote vagal activity more than atenolol.

Published
2004
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