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The paper presents the results of anterior spine fusion in 250 patients with tuberculous spondylitis involving 2 to 8 vertebrae, by using free and non-free autologous bone grafts, carbonaceous implants, and revascularized transplants. Anterior spine fusion added to posterior spinal fixation with a CD-type metal construction. A tuberculous process in the spine was cured in 96.1% of cases; the spinal support capability recovery rate was 95.2% in the early postoperative period and in 93.5% in the late one.

The authors have developed an approach to cervicothoracic and upper thoracic spine for surgical treatment of patients with tuberculous spondylitis complicated by severe kyphotic deformity, which allows one to make the entire scope of reparative surgical intervention under visual guidance from the fifth cervical vertebra to the ninth thoracic one with the minimum traumaticity and preserved muscle integrity. This is performed through the periscapular triangle by diverting the scapula cranially without dissecting its fixing muscles, the musculus latissimus dorsa caudally. The third or fourth rib is resected in relation to the site of a pathological process.

Patterns of collagen metabolism were studied in 36 patients with hematogenic vertebral column osteomyelitis simultaneously with evaluation of C-reactive protein, haptoglobin and ceruloplasmin in blood and consideration of the clinico-morphological steps of the disease. Hyperhydroxyprolineuria proved to be a more informative evidence for inflammation in vertebral column as compared with the proteins of acute phase of inflammation importance of hydroxyproline measurement in biological fluids for evaluation of the osteomyelitis development was elevated as the inflammation activity decreased (which was estimated by content of the acute phase proteins).