266 results on '"Dzamko, Nicolas"'
Search Results
2. Novel tools to quantify total, phospho-Ser129 and aggregated alpha-synuclein in the mouse brain
3. Prediction of motor and non-motor Parkinson’s disease symptoms using serum lipidomics and machine learning: a 2-year study
4. A protective role of ABCA5 in response to elevated sphingomyelin levels in Parkinson’s disease
5. A potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
6. Evaluation of plasma levels of NFL, GFAP, UCHL1 and tau as Parkinson's disease biomarkers using multiplexed single molecule counting
7. A small molecule toll-like receptor antagonist rescues α-synuclein fibril pathology
8. Immune responses in the Parkinson's disease brain
9. Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain
10. Effect of LRRK2 protein and activity on stimulated cytokines in human monocytes and macrophages
11. Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation
12. Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α‑Synuclein Fibrils.
13. LRRK2 kinase inhibitors reduce alpha-synuclein in human neuronal cell lines with the G2019S mutation
14. Pathological manifestation of human endogenous retrovirus K in frontotemporal dementia
15. Autophagy activation promotes clearance of α-synuclein inclusions in fibril-seeded human neural cells
16. New Antibodies to Advance Glucocerebrosidase Research
17. Cytokine activity in Parkinson’s disease
18. Nigrostriatal pathology with reduced astrocytes in LRRK2 S910/S935 phosphorylation deficient knockin mice
19. Recent Developments in LRRK2-Targeted Therapy for Parkinson’s Disease
20. LRRK2 and the Immune System
21. Live cell in situ lysosomal GCase activity correlates to alpha-synuclein levels in human differentiated neurons with LRRK2 and GBA1 mutations
22. A blood-based marker of mitochondrial DNA damage in Parkinson’s disease
23. Parkinson’s progression prediction using machine learning and serum cytokines
24. A potential patient stratification biomarker for Parkinson's disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
25. Editorial: Updates on inflammation in Parkinson's disease
26. Multiple pathways of lipid dysregulation in amyotrophic lateral sclerosis
27. Toll-like receptor 2 is increased in neurons in Parkinson’s disease brain and may contribute to alpha-synuclein pathology
28. Reduced glucocerebrosidase activity in monocytes from patients with Parkinson’s disease
29. LRRK2 and Lipid Pathways: Implications for Parkinson’s Disease
30. Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones
31. Reduced LRRK2 in association with retromer dysfunction in post-mortem brain tissue from LRRK2 mutation carriers
32. LRRK2 levels and phosphorylation in Parkinsonʼs disease brain and cases with restricted Lewy bodies
33. WHOPPA Enables Parallel Assessment of Leucine-Rich Repeat Kinase 2 and Glucocerebrosidase Enzymatic Activity in Parkinson’s Disease Monocytes
34. Lipid pathway dysfunction is prevalent in patients with Parkinson’s disease
35. Sex-specific lipid dysregulation in the Abca7 knockout mouse brain
36. Additional file 1 of Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain
37. Increased Peripheral Inflammation in Asymptomatic Leucine-Rich Repeat Kinase 2 Mutation Carriers
38. Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity
39. AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance
40. Chemoselective Bioconjugation of Amyloidogenic Protein Antigens to PEGylated Microspheres Enables Detection of α-Synuclein Autoantibodies in Human Plasma
41. Multiple pathways of lipid dysregulation in amyotrophic lateral sclerosis.
42. DNA extraction from fresh-frozen and formalin-fixed, paraffinembedded human brain tissue
43. Comparison of Different Platform Immunoassays for the Measurement of Plasma Alpha-Synuclein in Parkinson’s Disease Patients
44. Evaluation of Strategies for Measuring Lysosomal Glucocerebrosidase Activity
45. Glucocerebrosidase Activity is Reduced in Cryopreserved Parkinson’s Disease Patient Monocytes and Inversely Correlates with Motor Severity
46. CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
47. Single‐Molecule Counting Coupled to Rapid Amplification Enables Detection of α‐Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease Patients
48. Unlocking the secrets of LRRK2 function with selective kinase inhibitors
49. Sex-specific lipid dysregulation in the Abca7 knockout mouse brain.
50. Cytokines and Gaucher Biomarkers in Glucocerebrosidase Carriers with and Without Parkinson Disease
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