Search

Your search keyword '"Dwyer, Robert"' showing total 345 results
Start Over Author "Dwyer, Robert"
345 results on '"Dwyer, Robert"'

3. Amplitude Parameters Are Predictive of Hearing Preservation in a Randomized Controlled Trial of Intracochlear Electrocochleography During Cochlear Implant Surgery.

Author

Harris, Michael S., Koka, Kanth, Thompson-Harvey, Adam, Harvey, Erin, Riggs, William J., Saleh, Shaza, Holder, Jordan T., Dwyer, Robert T., Prentiss, Sandra M., Lefler, Shannon M., Kozlowski, Kristin, Hiss, Meghan M., Ortmann, Amanda J., Nelson-Bakkum, Erin R., Büchner, Andreas, Salcher, Rolf, Harvey, Steven A., Hoffer, Michael E., Bohorquez, Jorge E., and Alzhrani, Farid

Published
2024
Full Text
View/download PDF

4. A Graph-Based Method for Optimal Active Electrode Selection in Cochlear Implants

Author

Bratu, Erin, Dwyer, Robert, Noble, Jack, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Martel, Anne L., editor, Abolmaesumi, Purang, editor, Stoyanov, Danail, editor, Mateus, Diana, editor, Zuluaga, Maria A., editor, Zhou, S. Kevin, editor, Racoceanu, Daniel, editor, and Joskowicz, Leo, editor

Published
2020
Full Text
View/download PDF

5. Inferring interaction partners from protein sequences

Author

Bitbol, Anne-Florence, Dwyer, Robert S., Colwell, Lucy J., and Wingreen, Ned S.

Subjects
Physics - Biological Physics, Quantitative Biology - Biomolecules
Abstract

Specific protein-protein interactions are crucial in the cell, both to ensure the formation and stability of multi-protein complexes, and to enable signal transduction in various pathways. Functional interactions between proteins result in coevolution between the interaction partners, causing their sequences to be correlated. Here we exploit these correlations to accurately identify which proteins are specific interaction partners from sequence data alone. Our general approach, which employs a pairwise maximum entropy model to infer couplings between residues, has been successfully used to predict the three-dimensional structures of proteins from sequences. Thus inspired, we introduce an iterative algorithm to predict specific interaction partners from two protein families whose members are known to interact. We first assess the algorithm's performance on histidine kinases and response regulators from bacterial two-component signaling systems. We obtain a striking 0.93 true positive fraction on our complete dataset without any a priori knowledge of interaction partners, and we uncover the origin of this success. We then apply the algorithm to proteins from ATP-binding cassette (ABC) transporter complexes, and obtain accurate predictions in these systems as well. Finally, we present two metrics that accurately distinguish interacting protein families from non-interacting ones, using only sequence data., Comment: 25 pages, 19 figures, published version

Published
2016
Full Text
View/download PDF

7. Can Electrocochleography Help Preserve Hearing After Cochlear Implantation With Full Electrode Insertion?

Author

Harris, Michael S., Koka, Kanth, Riggs, William J., Saleh, Shaza, Holder, Jourdan T., Dwyer, Robert T., Prentiss, Sandra, Lefler, Shannon, Kozlowski, Kristin, Hiss, Megan M., Ortmann, Amanda J., Nelson-Bakkum, Erin, Büchner, Andreas, Salcher, Rolf, Harvey, Steven A., Hoffer, Michael E., Bohorquez, Jorge E., Alzhrani, Farid, Alshihri, Rana, Fida, Almuhawas, Danner, Christopher J., Friedland, David R., Seidman, Michael D., Lenarz, Thomas, Telischi, Fred F., Labadie, Robert F., Buchman, Craig A., and Adunka, Oliver F.

Published
2022
Full Text
View/download PDF

11. Augmenting ESL Class Evaluations through Oral Journals.

Author

Dwyer, Robert

Abstract

An experiment using audiotaped student journals for course evaluation is described. Subjects were 200 native Cantonese-speaking technology students taking credit-bearing courses in English communication skills for building. One of the required tasks in the course was to indicate, in their oral journals, what they liked about an instructional module on communication skills for building purposes, and what they would do to improve it. The report summarizes the study and presents excerpts from both students' and teacher's comments on specific module activities, including: reading of newspaper and magazine articles on building-related topics; writing about both physical attributes and building processes in technical writing tasks; group oral work; oral journals; general oral activities; and listening quizzes. It is concluded that substantial information concerning curriculum strengths and weaknesses was derived from the students' oral journals, and that the method is useful for tapping student perceptions that might otherwise not be revealed. (MSE)

Published
1994

12. Redesigning an EAP Curriculum: Problems, Needs, Solutions and Teacher Development.

Author

Dwyer, Robert

Abstract

A Hong Kong college instructor in English for academic purposes (EAP) describes the process of revising an instructional module designed for students involved in the building trades. The three-step curriculum development process included (1) personal reflection and solicitation of student perceptions; (2) need analysis and development of a new module and detailed teaching plan; (3) reflection on and discussion of initial implementation of the revised module. The project arose from the discovery that a module designed for one program was being used in three new programs, all in related but different subspecialties: building services engineering; architecture; and surveying. The revised module features increased emphasis on student listening skills in English and on development of student confidence in speaking. It is concluded that while students perceive the new module as effective in meeting their language needs, it is still unclear as to whether it is meeting its objectives. A reflection on the professional development that occurred during the investigation concludes the paper. A glossary, syllabus, and student evaluation of teaching questionnaire are appended. Contains 24 references. (MSE)

Published
1993

14. CROS or hearing aid? Selecting the ideal solution for unilateral CI patients with limited aidable hearing in the contralateral ear.

Author

Lively, Sarah, Agrawal, Smita, Stewart, Matthew, Dwyer, Robert T., Strobel, Laura, Marcinkevich, Paula, Hetlinger, Chris, and Croce, Julia

Subjects
HEARING aids, COCHLEAR implants, SPEECH perception, EAR, SPEECH
Abstract

A hearing aid or a contralateral routing of signal device are options for unilateral cochlear implant listeners with limited hearing in the unimplanted ear; however, it is uncertain which device provides greater benefit beyond unilateral listening alone. Eighteen unilateral cochlear implant listeners participated in this prospective, within-participants, repeated measures study. Participants were tested with the cochlear implant alone, cochlear implant + hearing aid, and cochlear implant + contralateral routing of signal device configurations with a one-month take-home period between each in-person visit. Audiograms, speech perception in noise, and lateralization were evaluated. Subjective feedback was obtained via questionnaires. Marked improvement in speech in noise and non-implanted ear lateralization accuracy were observed with the addition of a contralateral hearing aid. There were no significant differences in speech recognition between listening configurations. However, the chronic device use questionnaires and the final device selection showed a clear preference for the hearing aid in spatial awareness and communication domains. Individuals with limited hearing in their unimplanted ears demonstrate significant improvement with the addition of a contralateral device. Subjective questionnaires somewhat contrast with clinic-based outcome measures, highlighting the delicate decision-making process involved in clinically advising one device or another to maximize communication benefits. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

19. Electrode array positioning after cochlear reimplantation from single manufacturer.

Author

Smetak, Miriam R., Fernando, Shanik J., O'Malley, Matthew R., Bennett, Marc L., Haynes, David S., Wootten, Christopher T., Virgin, Frank W., Dwyer, Robert T., Dawant, Benoit M., Noble, Jack H., and Labadie, Robert F.

Subjects
PATIENT positioning, REOPERATION, ELECTRODES, MANUFACTURING industries, COMPUTED tomography, COCHLEAR implants, DATABASES
Abstract

To investigate whether revision surgery with the same device results in a change in three key indicators of electrode positioning: scalar location, mean modiolar distance ( M ¯ ), and angular insertion depth (AID). Retrospective analysis of a cochlear implant database at a university-based tertiary medical center. Intra-operative CT scans were obtained after initial and revision implantation. Electrode array (EA) position was calculated using auto-segmentation techniques. Initial and revision scalar location, M ¯ , and AID were compared. Mean change in M ¯ for all ears was −0.07 mm (SD 0.24 mm; P = 0.16). The mean change in AID for all ears was −5° (SD 67°; P = 0.72). Three initial implantations with pre-curved EAs resulted in a translocation from Scala Tympani (ST) to Scala Vestibuli (SV). Two remained translocated after revision, while one was corrected when revised with a straight EA. An additional five translocations occurred after revision. In this study examining revision cochlear implantation from a single manufacturer, we demonstrated no significant change in key indicators of EA positioning, even when revising with a different style of electrode. However, the revision EA is not necessarily confined by the initial trajectory and there may be an increased risk of translocation. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

24. Observational Study of Receptor Binding Domain Spike Antibody Responses to 3 SARS-CoV-2 Vaccinations in Noninfected Subjects: Parallel Neutralizing Antibody and Cardiac Troponin I and T Observations

Author

Apple, Fred S, primary, Bothwell, Bryan, additional, Koti, Jaya, additional, Bauer, Westley, additional, Dwyer, Robert, additional, Chen, Haode, additional, Wu, Heng, additional, Li, Pu, additional, Lindgren, Britanny, additional, Gottlieb, Sydney, additional, Okeson, Brynn, additional, and Schulz, Karen, additional

Published
2022
Full Text
View/download PDF

27. An Evaluation of the Effectiveness of a New Type of Preschool Compensatory Program: Environmental Academics.

Author

Dwyer, Robert C.

Abstract

A total of 160 five-year-old children from Head Start-eligible families were assigned to two treatments during a 6-month Head Start program. The experimental group received the Environmental Academics Program for one to one and a half hours per school day, and the ongoing Head Start program for the balance of the day. The control group received the ongoing Head Start program for the full day. The experimental group made significant gains over the control group on IQ and achievement measures. (Author/DB)

Published
1972

28. Student's Field Log for Grouping Animals, Working Paper. Second Revision.

Author

University City School District, MO. and Dwyer, Robert L.

Abstract

This field log for grouping animals is developed around a field experience at the zoo. The field guide is organized in three sections. Section one, for use before the field trip, develops the basic concept of classification. Section two, for use at the zoo, guides the students to make direct observations to classify the animals. Section three, for use after the field trip, leads the student to other aspects of classification. The log is designed for use by elementary school students. This work was prepared under an ESEA Title III contract. (BB)

Published
1968

30. From Marking to Feedback: Audiotaped Responses to Student Writing.

Author

Boswood, Tim and Dwyer, Robert H.

Abstract

Describes an action research project designed to experiment with alternative forms of feedback and to circumvent the less helpful aspects of written marking. As part of the project, four writing teachers formed an action research group to investigate the feasibility of offering audiotaped feedback in a systematic fashion to groups of students. (15 references) (CK)

Published
1996

33. Supporting Equity and Inclusion of Deaf and Hard-of-Hearing Individuals in Professional Organizations

Author

Huyck, Julia Jones, primary, Anbuhl, Kelsey L., additional, Buran, Brad N., additional, Adler, Henry J., additional, Atcherson, Samuel R., additional, Cakmak, Ozan, additional, Dwyer, Robert T., additional, Eddolls, Morgan, additional, El May, Fadhel, additional, Fraenzer, Juergen-Theodor, additional, Funkhouser, Rebekah, additional, Gagliardini, Mathilde, additional, Gallun, Frederick J., additional, Goldsworthy, Raymond L., additional, Gouin, Samir, additional, Heng, Joseph, additional, Hight, Ariel Edward, additional, Jawadi, Zina, additional, Kovacic, Damir, additional, Kumar, Rachit, additional, Kumar, Santosh, additional, Lim, Stacey R., additional, Mo, Chengeng, additional, Nolan, Lisa S., additional, Parbery-Clark, Alexandra, additional, Pisano, Dominic V., additional, Rao, Valluri R., additional, Raphael, Robert M., additional, Reiss, Lina A. J., additional, Spencer, Nathaniel J., additional, Tang, Stephen J., additional, Tejani, Viral D., additional, Tran, Emma D., additional, Valli, Mikaeel, additional, Watkins, Greg D., additional, Wayne, Rachel V., additional, Wheeler, Lindsey R., additional, White, Stephanie L., additional, Wong, Victor, additional, Yuk, M. Caroline, additional, Ratnanather, J. Tilak, additional, and Steyger, Peter S., additional

Published
2021
Full Text
View/download PDF

35. Observational Study of Receptor Binding Domain Spike Antibody Responses to 3 SARS-CoV-2 Vaccinations in Noninfected Subjects: Parallel Neutralizing Antibody and Cardiac Troponin I and T Observations .

Author

Apple, Fred S, Bothwell, Bryan, Koti, Jaya, Bauer, Westley, Dwyer, Robert, Chen, Haode, Wu, Heng, Li, Pu, Lindgren, Britanny, Gottlieb, Sydney, Okeson, Brynn, and Schulz, Karen

Subjects
TROPONIN I, ANTIBODY formation, MICROFILAMENT proteins, VACCINATION, SARS-CoV-2, SCIENTIFIC observation, COPEPTINS
Abstract

Background: Our goals were to demonstrate receptor binding domain spike 1 (RBD S1) protein antibody (Ab) kinetic responses to multiple vaccines over approximately 180 days, neutralizing Ab effectiveness, and high-sensitivity cardiac troponin I (hs-cTnI) and T (hs-cTnT) responses in postvaccinated, non-SARS-CoV-2–infected subjects. Methods: Blood specimens were collected pre- and postvaccinations from seronegative subjects. RDB S1 Abs were measured by the novel Qorvo Biotechnologies Omnia platform. Neutralizing Abs and hs-cTnI and hs-cTnT were measured on the ET Healthcare Pylon 3D. Results: Two-dose vaccines (Pfizer, Moderna) had peak RBD S1 Ab concentrations about 45 to 55 days after both doses and showed declines over the next 50 to 70 days. The Janssen vaccine showed lower RBD S1 Ab peak concentrations, continued to increase over time, and plateaued after 60 days. There was strong neutralizing Ab response post vaccinations, with only 3 specimens, shortly before and shortly after vaccination, not showing a response. Specimens showed no hs-cTnI (all < 3 ng/L) and hs-cTnT (all < 6 ng/L) increases or changes over time. Conclusions: We demonstrate in seronegative SARS-CoV-2 subjects that Pfizer and Moderna vaccinations provide strong, neutralizing RBD S1 Ab effectiveness, based on 2 different assays after 2 doses, with the Janssen single-dose vaccine showing a lower RBD S1 Ab response over 4 to 6 months. No myocardial injury was associated with the Pfizer postvaccination. The Qorvo Biotechnologies RBD S1 Ab assay measured on the Omnia platform has potential as a point-of-care platform. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

38. Chapter Letters

Author

Duncan, John, Dwyer, Robert, Hill, Jane, Liu, Robert K., Baltzell, James, and Olson, Robert E.

Published
1960

43. Toward Sustainable Environmental Quality: Priority Research Questions for Asia

Author

Leung, Kenneth M.Y., primary, Yeung, Katie W.Y., additional, You, Jing, additional, Choi, Kyungho, additional, Zhang, Xiaowei, additional, Smith, Ross, additional, Zhou, Guang‐Jie, additional, Yung, Mana M.N., additional, Arias‐Barreiro, Carlos, additional, An, Youn‐Joo, additional, Burket, S. Rebekah, additional, Dwyer, Robert, additional, Goodkin, Nathalie, additional, Hii, Yii Siang, additional, Hoang, Tham, additional, Humphrey, Chris, additional, Iwai, Chuleemas Boonthai, additional, Jeong, Seung‐Woo, additional, Juhel, Guillaume, additional, Karami, Ali, additional, Kyriazi‐Huber, Katerina, additional, Lee, Kuan‐Chun, additional, Lin, Bin‐Le, additional, Lu, Ben, additional, Martin, Patrick, additional, Nillos, Mae Grace, additional, Oginawati, Katharina, additional, Rathnayake, I.V.N., additional, Risjani, Yenny, additional, Shoeb, Mohammad, additional, Tan, Chin Hon, additional, Tsuchiya, Maria Claret, additional, Ankley, Gerald T., additional, Boxall, Alistair B.A., additional, Rudd, Murray A., additional, and Brooks, Bryan W., additional

Published
2020
Full Text
View/download PDF

47. Bioaccumulation

Author

Schlekat, Christian, primary, McGeer, James, additional, Blust, Ronny, additional, Borgmann, Uwe, additional, Brix, Kevin, additional, Bury, Nicolas, additional, Couillard, Yves, additional, Dwyer, Robert, additional, Luoma, Samuel, additional, Robertson, Steve, additional, Sappington, Keith, additional, Schoeters, Ilse, additional, and Sijm, Dick, additional

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results