169 results on '"Dutschman, Ginger E."'
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2. Identification of chemicals and their metabolites from PHY906, a Chinese medicine formulation, in the plasma of a patient treated with irinotecan and PHY906 using liquid chromatography/tandem mass spectrometry (LC/MS/MS)
3. Quantitation of Irinotecan and its two major metabolites using a liquid chromatography–electrospray ionization tandem mass spectrometric
4. Unique Spectrum of Activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against Herpesviruses in vitro and Its Mode of Action against Herpes Simplex Virus Type 1
5. Highly selective action of triphosphate metabolite of 4′-ethynyl D4T: A novel anti-HIV compound against HIV-1 RT
6. Analysis of deoxyribonucleotide pools in human cancer cell lines using a liquid chromatography coupled with tandem mass spectrometry technique
7. Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture
8. Tylophorine Analogs Allosterically Regulates Heat Shock Cognate Protein 70 And Inhibits Hepatitis C Virus Replication
9. Bifunctional inhibition of HIV-1 reverse transcriptase: A first step in designing a bifunctional triphosphate
10. Blocking HIV-1 entry by a gp120 surface binding inhibitor
11. Discovery of a synthetic dual inhibitor of HIV and HCV infection based on a tetrabutoxy-calix[4]arene scaffold
12. Synthesis of 4′-Ethynyl-2′-deoxy-4′-thioribonucleosides and Discovery of a Highly Potent and Less Toxic NRTI
13. Determinants of Individual Variation in Intracellular Accumulation of Anti-HIV Nucleoside Analog Metabolites
14. Reversal of TNP-470-Induced Endothelial Cell Growth Arrest by Guanine and Guanine Nucleosides
15. ChemInform Abstract: Synthesis and Biological Evaluation of L- and D-Configurations of 2′,3′-Dideoxy-4′-C-methyl-3′-oxacytidine Analogues.
16. ChemInform Abstract: Synthesis of Halogen-Substituted 3-Deazaadenosine and 3-Deazaguanosine Analogues as Potential Antitumor/Antiviral Agents.
17. A Novel Class of meso -Tetrakis-Porphyrin Derivatives Exhibits Potent Activities against Hepatitis C Virus Genotype 1b Replicons In Vitro
18. Impact of Novel Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutations P119S and T165A on 4′-Ethynylthymidine Analog Resistance Profile
19. Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture
20. Synthesis and Anti-HIV Activity of 4′-Substituted 4′-Thiothymidines: A New Entry Based on Nucleophilic Substitution of the 4′-Acetoxy Group
21. Mechanism of Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase by a Stavudine Analogue, 4′-Ethynyl Stavudine Triphosphate
22. Intracellular Metabolism and Persistence of the Anti-Human Immunodeficiency Virus Activity of 2′,3′-Didehydro-3′-Deoxy-4′-Ethynylthymidine, a Novel Thymidine Analog
23. Comparison of the Phosphorylation of 4′-Ethynyl 2′,3′-Dihydro-3′-Deoxythymidine with That of Other Anti-Human Immunodeficiency Virus Thymidine Analogs
24. 3'-Carbon-Substituted Pyrimidine Nucleosides Having a 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy Structure: Synthesis and Antiviral Evaluation
25. Synthesis and Biological Evaluation of 2′-3′-Didehydro-2′,3′-dideoxy-9-deazaguanosine, a Monophosphate Prodrug and Two Analogues, 2′,3′-Dideoxy-9-deazaguanosine and 2′,3′-Didehydro-2′,3′-dideoxy-9-deazainosine.
26. Synthesis of (.+‐.)‐4′‐Ethynyl and 4′‐Cyano Carbocyclic Analogues of Stavudine (d4T).
27. Mechanism of Anti-Human Immunodeficiency Virus Activity of β- d -6-Cyclopropylamino-2′,3′-Didehydro-2′,3′-Dideoxyguanosine
28. Behavior of Thymidylate Kinase toward Monophosphate Metabolites and Its Role in the Metabolism of 1-(2′-Deoxy-2′-Fluoro-β- l -Arabinofuranosyl)-5-Methyluracil (Clevudine) and 2′,3′-Didehydro-2′,3′-Dideoxythymidine in Cells
29. A NEW APPROACH TO THE SYNTHESIS OF 4′-CARBON-SUBSTITUTED NUCLEOSIDES: DEVELOPMENT OF A HIGHLY ACTIVE ANTI-HIV AGENT 2′, 3′-DIDEHYDRO-3′-DEOXY-4′-ETHYNYLTHYMIDINE
30. Synthesis of (±)-4′-Ethynyl and 4′-Cyano Carbocyclic Analogues of Stavudine (d4T)
31. Synthesis and Biological Evaluation of 2′,3′-Didehydro-2′,3′-Dideoxy-9-Deazaguanosine, a Monophosphate Prodrug and Two Analogues, 2′,3′-Dideoxy-9-Deazaguanosine and 2′,3′-Didehydro-2′,3′-Dideoxy-9-Deazainosine
32. Synthesis and Anti‐HIV Activity of 4′‐Cyano‐2′,3′‐didehydro‐3′‐deoxythymidine
33. Synthesis and Antiviral Activity of Helioxanthin Analogues
34. Phosphorylation of Cytidine, Deoxycytidine, and Their Analog Monophosphates by Human UMP/CMP Kinase Is Differentially Regulated by ATP and Magnesium
35. Synergistic Antitumor Activity of Troxacitabine and Camptothecin in Selected Human Cancer Cell Lines
36. Novel 4′-Substituted Stavudine Analog with Improved Anti-Human Immunodeficiency Virus Activity and Decreased Cytotoxicity
37. Reverse Transcriptase Activity of Hepatitis B Virus (HBV) DNA Polymerase within Core Capsid: Interaction with Deoxynucleoside Triphosphates and Anti-HBV l-Deoxynucleoside Analog Triphosphates
38. Novel Role of 3-Phosphoglycerate Kinase, a Glycolytic Enzyme, in the Activation of L-Nucleoside Analogs, a New Class of Anticancer and Antiviral Agents
39. Assessment of the Effect of Phosphorylated Metabolites of Anti-Human Immunodeficiency Virus and Anti-Hepatitis B Virus Pyrimidine Analogs on the Behavior of Human Deoxycytidylate Deaminase
40. Synthesis and biological evaluation of l- and d-configurations of 2′,3′-dideoxy-4′-c-methyl-3′-oxacytidine analogues
41. ChemInform Abstract: Synthesis and Biological Evaluation of L- and D-Configuration 1,3-Dioxolane 5-Azacytosine and 6-Azathymine Nucleosides.
42. Anti-Epstein-Barr Virus (EBV) Activity of β- l -5-Iododioxolane Uracil Is Dependent on EBV Thymidine Kinase
43. Metabolism and Mode of Inhibition of Varicella-Zoster Virus byl-β-5-Bromovinyl-(2-hydroxymethyl)-(1,3-dioxolanyl)uracil Is Dependent on Viral Thymidine Kinase
44. ChemInform Abstract: Synthesis and Biological Evaluation of 1,3-Oxathiolane 5-Azapyrimidine, 6-Azapyrimidine, and Fluorosubstituted 3-Deazapyrimidine Nucleosides.
45. Synthesis and biological evaluation of l- and d-configuration 1,3-dioxolane 5-azacytosine and 6-azathymine nucleosides
46. Synthesis and Biological Evaluation of 1,3-Oxathiolane 5-Azapyrimidine, 6-Azapyrimidine, and Fluorosubstituted 3-Deazapyrimidine Nucleosides
47. ChemInform Abstract: Synthesis of 2′‐Methylene‐Substituted 5‐Azapyrimidine, 6‐Azapyrimidine, and 3‐Deazaguanine Nucleoside Analogues as Potential Antitumor/Antiviral Agents.
48. ChemInform Abstract: Synthesis and Comparative Evaluation of Two Antiviral Agents: β‐L‐Fd4C and β‐D‐Fd4C.
49. Synthesis and comparative evaluation of two antiviral agents: β-l-Fd4C and β-d-Fd4C
50. Synthesis and biological evaluation of a series of 2′-fluorinated-2′,3′-dideoxy-2′,3′-didehydro-(l)-nucleosides
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